1 PUBLICATIONS Peer reviewed articles 1. Ljung G, Norberg M, Hansson H, de la Torre, Egevad L, Busch C, Nilsson S: Transrectal ultrasonically guided core biopsies in the assessment of local cure of prostatic cancer after radical external beam radiotherapy. (Acta Oncol. 1995; 34:945-952) 2. Norberg M, Holmberg L, Busch C, Häggman M, Egevad L, Magnusson A: Multiple transrectal ultrasound guided biopsies for the detection of prostate cancer, determination of tumour volume, grade and seminal vesicle invasion. (Eur Radiol. 1996; 6:56-61) 3. Ljung G, Egevad L, Norberg M, de la Torre M, Holmberg L, Busch C, Nilsson S: Assessment of proliferation indicators in residual prostatic adenocarcinoma cells after radical external beam radiotherapy. (The Prostate. 1996; 29:303-310) 4. Ljung G, Egevad L, Norberg M, Holmberg L, Nilsson S, Busch C: Expression of p21 and mutant p53 gene products in residual prostatic tumor cells after radical radiotherapy. (Prostate. 1997; 32(2):99-105) 5. Ranefall P, Egevad L, Nordin B, Busch C, Bengtsson E: A new method for segmentation of colour images applied on immunohistochemically stained cells. (Analytical Cellular Pathology. 1997; 15:145-156) 6. Bjelfman C, Söderström T, Brekkan E, Norlén B-J, Egevad L, Unge T, Andersson S, Rane A: Differential gene expression of steroid 5a-reductase 2 in in core needle biopsies from malignant and benign prostatic tissue. (J Clin Endocrinol Metab. 1997; 82(7):2210-2214) 7. Norberg M, Egevad L, Holmberg L, Norlén B-J, Busch C: The sextant protocol for ultrasound-guided core biopsies of the prostate underestimates the presence of cancer. (Urology. 1997; 50:562-566) 8. Sundstrom C, Egevad L: More pathologists are needed in Sweden! Retirements may cause a real crisis. (Lakartidningen. 1997; 94(26-27):2443) 9. Loughlin M, Carlbom I, Busch C, Douglas T, Egevad L, Frimmel H, Norberg M, Sesterhenn I, Frogge J: Three-dimensional modeling of biopsy protocols for localized prostate cancer. (Computerized Medical Imaging and Graphics. 1998; 22 (3):229-238) 10. Egevad L, Norberg M, Mattson S, Norlén B J, Busch C: Estimation of prostate cancer volume by multiple core biopsies before radical prostatectomy. (Urology. 1998; 52(4):653-658) 11. Egevad L, Engström K, Busch C: A new method for handling radical prostatectomies enabling fresh tissue harvesting, whole mount sections and landmarks for alignment of sections. (Journal of Urologic Pathology. 1998; 9:17-28) 12. Busch C, Egevad L, Häggman M: Precancer of the prostate (Cancer Surveys Volume 32: In Precancer: Biology, importance and possible prevention. Precancer of the prostate. 1998, 149-179) 13. Egevad L, Frimmel H, Norberg M, Mattson S, Carlbom I, Bengtsson E, Busch C: Three-dimensional computer reconstruction of prostate cancer from radical prostatectomy specimens: Evaluation of the model by core biopsy simulation. (Urology. 1999; 53:192-198) 14. Nilsson BO, Egevad L, Jin M, Ronquist G, Busch C: Distribution of prostasomes in neoplastic epithelial prostate cells. (Prostate. 1999; 39:36-40) 15. Yang K, Lindblad P, Egevad L, Hemminki K: Novel somatic mutations in the VHL gene in Swedish archived sporadic renal cell carcinomas. (Cancer Letters.1999; 141(1-2):1-8) 16. Egevad L, Engström K, Mattson S, Wester K, Busch C: Heterogeneity of DNA ploidy in prostate cancer. (Journal of Urologic Pathology. 1999; 10:23-37) 17. Egevad L, Frimmel H, Mattson S, Bengtsson E, Busch C: Biopsy protocol stability in a three-dimensional model of prostate cancer: Changes in cancer yield after adjustment of biopsy positions. (Urology.1999; 54(5):862-868) 18. Frimmel H, Egevad L, Bengtsson E, Busch C: Modeling prostate cancer distributions. (Urology. 1999; 54(6):1028-1034) 19. Franck Lissbrant I, Stattin P, Wikström P, Damber J-E, Egevad L, Bergh A: Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival. (Int J Oncol.2000; 17(3):445-51) 20. Stattin P, Bylund A, Rinaldi S, Biessy C, Déchaud H, Stenman U-H, Egevad L, Riboli E, Hallmans G, Kaaks R: Plasma insulin-like growth factor-I, insulin-like growth factor-binding proteins, and prostate cancer risk: a prospective study. (J Natl Cancer Inst. 2000; 92(23):1910-7) 21. Söderström T, Bjelfman C, Brekkan E, Ask B, Egevad L, Norlén B J , Rane A: Messenger ribonucleic acid levels of steroid 5alpha-reductase 2 in human prostate predict the enzyme activity. (Clin Endocrinol Metab. 2001; 86(2):855858) 22. Egevad L: Reproducibility of Gleason grading of prostate cancer can be improved by the use of reference images. (Urology. 2001; 57 (2): 291-5) 2 23. Alaiya A, Roblick U, Egevad L, Carlsson A, Franzén B, Volz D, Huwendiek S, Linder S, Auer G: Polypeptide expression in prostate hyperplasia and prostate adenocarcinoma. (Analytical Cellular Pathology. 2001; 21(1):1-9) 24. Alaiya A, Oppermann M, Langridge J, Roblick U, Egevad L, Brändstedt S, Hellström M, Linder S, Bergman T, Jörnvall H, Auer G: Identification of proteins in human prostate tumor material by two-dimensional gel electrophoresis and mass spectrometry. (Cell Mol. Life Sciences. 2001; 58(2):307-11) 25. Ma X, Yang K, Lindblad P, Egevad L, Hemminki K: VHL gene alteration in renal cell carcinoma patients: Novel hotspot or founder mutation and linkage disequilibrium. (Oncogene. 2001; 20(38):5393-400) 26. Egevad L, Norlén B J , Norberg M: The value of multiple core biopsies for predicting the Gleason score of prostate cancer. (BJU Int. 2001; 88:716-721) 27. Andersson J, Ekman P, Egevad L, Hellström M: Relatively high risk of treatment failure after prostatectomy: Tumour grade, histopathological stage and the preoperative serum PSA level are key prognosticators. (Scand J Urol Nephrol. 2001; 35 (6):453-458) 28. Finnström N, Bjelfman C, Söderström T, Smith G, Egevad L, Norlén B-J, Wolf R, Rane A: Detection of cytochrome P450 mRNA transcripts in prostate samples by RT-PCR. (Eur J Clin Invest. 2001; 31(10): 880-6) 29. Frimmel H, Egevad L, Busch C, Bengtsson E: Automatic registration and error detection of multiple slices using landmarks. (Anal Cell Pathol. 2001; 23(3,4):159-165) 30. Hemminki K, Jiang Y, Ma X, Yang K, Egevad L, Lindblad P: Molecular epidemiology of VHL gene mutations in renal cell carcinoma patients: Relation to dietary and other factors. (Carcinogenesis. 2002; 23(5):809-815) 31. Egevad L, Granfors T, Karlberg L, Bergh A, Stattin P: Prognostic value of the Gleason score in prostate cancer. (BJU Int. 2002; 89(6):538-42) 32. Wikström P, Franck Lissbrant I, Stattin P, Egevad L, Bergh A: Endoglin (CD105) is expressed on immature blood vessels and is a marker for survival in prostate cancer. (Prostate. 2002; 51(4):268-75) 33. Häggarth L, Ekman P, Egevad L: A new core-biopsy instrument with an end-cut technique provides prostate biopsies with increased tissue yield. (BJU Int, 2002; 90(1):51-5) 34. Sahlén G, Egevad L, Ahlander A, Norlén BJ, Ronquist G, Nilsson BO: Ultrastructure of the secretion of prostasomes from benign and malignant epithelial cells in the prostate. (The Prostate. 2002; 53(3):192-9) 3 35. Egevad L, Granfors T, Karlberg L, Bergh A, Stattin P: Percent Gleason grade 4/5 as prognostic factor in prostate cancer diagnosed at transurethral resection. (J Urol. 2002; 168(2):509-13) 36. Glaessgen A, Hamberg H, Pihl C-G, Sundelin B, Nilsson B, Egevad L: Interobserver reproducibility of percent Gleason grade 4/5 in total prostatectomy specimens. (J Urol. 2002; 168(5):2006-2010) 37. Egevad L: Cytology of the central zone of the prostate (Diagnostic Cytopathology. 2003; 28(5):239-44) 38. Richardsen E, Ukkonen T, Bjørnsen T, Mortensen R, Egevad L, Busch C: Overexpression of IGBFB2 is a marker for malignant transformation in prostate cancer. (Virchows Arch. 2003; 442(4):329-35) 39. Shiao Y, Forsti A, Egevad L, Amderson LM, Lindblad P, Hemminki K: VHL down-regulation and differential localization as mechanisms in tumorigenesis. (Kidney Int. 2003; 64(5):1671-4.) 40. Glaessgen A, Hamberg H, Pihl C-G, Sundelin B, Nilsson B, Egevad L: Interobserver reproducibility of percent Gleason grade 4/5 in prostate biopsies. (J Urol. 2004; 171(2 Pt 1):664-7) 41. Key TJ, Allen N, Appleby P, Overvad K, Tjonneland A, Miller A, Boeing H, Karalis D, Psaltopoulou T, Berrino F, Palli D, Panico S, Tumino R, Vineis P, Bueno-De-Mesquita HB, Kiemeney L, Peeters PH, Martinez C, Dorronsoro M, Gonzalez CA, Chirlaque MD, Quiros JR, Ardanaz E, Berglund G, Egevad L, Hallmans G, Stattin P, Bingham S, Day N, Gann P, Kaaks R, Ferrari P, Riboli E: Fruits and vegetables and prostate cancer: No association among 1,104 cases in a prospective study of 130,544 men in the European Prospective Investigation into Cancer and Nutrition (EPIC). (Int J Cancer. 2004; 109(1):119-24) 42. Lapointe J, Li C, Higgins JP, Van De Rijn M, Bair E, Montgomery K, Ferrari M, Egevad L, Rayford W, Bergerheim U, Ekman P, DeMarzo AM, Tibshirani R, Botstein D, Brown PO, Brooks JD, Pollack JR.: Gene expression profiling identifies clinically relevant subtypes of prostate cancer. (Proc Natl Acad Sci U S A. 2004; 101(3):811-6) 43. See-Tong Pang, Xioalei Fang, Alexander Valdman, Gunnar Norstedt, Åke Pousette, Lars Egevad* and Peter Ekman* (*Egevad and Ekman contributed equally): Expression of Ezrin in Prostatic Intraepithelial Neoplasia. (Urology. 2004; 63(3):609-12) 44. Valdman A, Fang X, Pang S, Ekman P, Egevad L: Pim-1 expression in prostate cancer and prostatic intraepithelial neoplasia. (The Prostate 2004; 60:367-71) 45. Glaessgen A, Hamberg H, Pihl C-G, Sundelin B, Nilsson B, Egevad L: Interobserver reproducibility of modified Gleason score in radical prostatectomy specimens. (Virchows Arch. 2004; 445(1):17-21) 4 46. Pavlenko M, Roos AK, Lundqvist A, Palmborg A, Miller AM, Ozenci V, Bergman B, Egevad L, Hellstrom M, Kiessling R, Masucci G, Wersall P, Nilsson S, Pisa P: A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer. (Br J Cancer. 2004; 91(4):688-94) 47. Lind AJ, Wikstrom P, Granfors T, Egevad L, Stattin P, Bergh A: Angiopoietin 2 expression is related to histological grade, vascular density, metastases, and outcome in prostate cancer. (Prostate. 2005; 62(4):394-9) 48. Roos AK, Pavlenko M, Charo J, Egevad L, Pisa P.: Induction of PSA-specific CTLs and anti-tumor immunity by a genetic prostate cancer vaccine. (Prostate. 2005; 62(3):217-23) 49. Egevad L, Allsbrook WC Jr, Epstein JI: Current practice of Gleason grading among genitourinary pathologists. (Hum Pathol. 2005; 36(1):5-9) 50. Ozenci V, Miller AM, Palmborg A, Egevad L, Jaremko GA, Kalkner KM, Pisa P.: Presence and specificity of tumor associated lymphocytes from ascites fluid in prostate cancer. (Prostate. 2005; 65(1):20-6) 51. Lexander H, Franzen B, Hirschberg D, Becker S, Hellstrom M, Bergman T, Jornvall H, Auer G, Egevad L.: Differential protein expression of normal anatomical zones of the prostate. (Proteomics. 2005; 5(10):2570-6) 52. Srigley JR, Amin M, Boccon-Gibod L, Egevad L, Epstein JI, Humphrey PA, Mikuz G, Newling D, Nilsson S, Sakr W, Wheeler TM, Montironi R: Prognostic and predictive factors in prostate cancer: historical perspectives and recent international consensus initiatives. (Scand J Urol Nephrol Suppl. 2005 May; (216):8-19) 53. Amin M, Boccon-Gibod L, Egevad L, Epstein JI, Humphrey PA, Mikuz G, Newling D, Nilsson S, Sakr W, Srigley JR, Wheeler TM, Montironi R. Prognostic and predictive factors and reporting of prostate carcinoma in prostate needle biopsy specimens. (Scand J Urol Nephrol Suppl. 2005 May;(216):20-33) 54. Epstein JI, Amin M, Boccon-Gibod L, Egevad L, Humphrey PA, Mikuz G, Newling D, Nilsson S, Sakr W, Srigley JR, Wheeler TM, Montironi R: Prognostic factors and reporting of prostate carcinoma in radical prostatectomy and pelvic lymphadenectomy specimens. (Scand J Urol Nephrol Suppl. 2005 May;(216):34-63) 55. Epstein JI, Allsbrook WC Jr, Amin MB, Egevad L; and the ISUP Grading Committee: The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. (Am J Surg Pathol. 2005; 29(9):1228-1242) 56. Josefsson A, Wikström P, Egevad L, Granfors T, Karlberg L, Stattin P, Bergh A: Non-aggressive Gleason score 6 prostate tumors can be identified by tumor size and vascular density. (Eur Urol. 2005; 48(4):577-83) 5 6 57. Valdman A, Fang X, Pang S, Nilsson B, Ekman P, Egevad L: Ezrin expression in prostate cancer and benign prostatic tissue. (Eur Urol. 2005; 48(5):852-7) 58. Häggarth L, Busch C , Norberg M, Norlén B J, Egevad L: Prediction of large prostate cancer volume by multiple core biopsies. (Scand J Urol Nephrol. 2005; 39(5):380-386) 59. Häggarth L, Auer G, Busch C , Norberg M, Häggman M, Egevad L: The significance of tumor heterogeneity for prediction of DNA ploidy of prostate cancer. (Scand J Urol Nephrol. 2005; 39(5):387-92) 60. Lexander H, Franzén B, Hellström B, Auer G, Jörnvall H, Egevad L: Proteomic analysis of protein expression in prostate cancer. (Anal Quant Cytol Histol. 2005; 27(5):263-72) 61. Fang X, Liu Z, Fan Y, Zheng C, Nilson S, Egevad L, Ekman P, Xu D: Switch to full-length of XAF1 mRNA expression in prostate cancer cells by the DNA methylation inhibitor. (Int J Cancer. 2006; 118(10):2485-9) 62. Egevad L, Allsbrook WC Jr, Epstein JI: Current practice of diagnosis and reporting of prostatatic intraepithelial neoplasia and glandular atypia among genitourinary pathologists. (Mod Pathol. 2006; 19(2):180-5) 63. Epstein JI, Allsbrook WC Jr, Amin MB, Egevad L: Update on the Gleason Grading System for prostate cancer: Results of an International Consensus Conference of Urologic Pathologists. (Adv Anat Pathol. 2006; 13(1):57-59) 64. Valdman A, Jonmarker S, Ekman P, Egevad L: Cytological features of prostatic intraepithelial neoplasia. (Diagn Cytopathol. 2006; 34(5):317-22) 65. Egevad L, Allsbrook WC Jr, Epstein JI: Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists. (Hum Pathol. 2006; 37(3):292-7) 66. Lexander H, Hellman U, Palmberg C, Auer G, Hellstrom M, Franzen B, Jornvall H, Egevad L: Evaluation of two sample preparation methods for prostate proteome analysis. (Proteomics. 2006; 6(13):3918-25) 67. Culp WD, Neal R, Massey R, Egevad L, Pisa P, Garland D: Proteomic analysis of tumor establishment and growth in the B16-F10 mouse melanoma model. (J Proteome Res. 2006; 5(6):1332-43) 68. Lexander H, Palmberg C, Hellman U, Auer G, Hellström M, Franzén B, Jörnvall H, Egevad L: Correlation of protein expression, Gleason score and DNA ploidy in prostate cancer. (Proteomics. 2006; 6(15):4370-80) 69. Jonmarker S, Valdman A, Lindberg A, Hellström M, Egevad L: Tissueshrinkage after fixation with formalin injection of prostatectomy specimens. (Virchows Archiv. 2006; 449(3): 297-301) 7 70. De Marzo AM, Platz EA, Epstein JI, Ali T, Billis A, Chan TY, Cheng L, Datta M, Egevad L, Ertoy-Baydar D, Farree X, Fine SW, Iczkowski KA, Ittmann M, Knudsen BS, Loda M, Lopez-Beltran A, Magi-Galluzzi C, Mikuz G, Montironi R, Pikarsky E, Pizov G, Rubin MA, Samaratunga H, Sebo T, Sesterhenn IA, Shah RB, Signoretti S, Simko J, Thomas G, Troncoso P, Tsuzuki TT, van Leenders GJ, Yang XJ, Zhou M, Figg WD, Hoque A, Lucia MS: A working group classification of focal prostate atrophy lesions. (Am J Surg Pathol. 2006;30(10):1281-91) 71. Eriksson F, Culp WD, Massey R, Egevad L, Garland D, Persson MA, Pisa P: Tumor specific phage particles promote tumor regression in a mouse melanoma model. (Cancer Immunol Immunother. 2007 May;56(5):677-87) 72. Hellström M, Lexander H, Franzén B, Egevad L: Proteomics in prostate cancer research. (Anal Quant Cytol Histol. 2007 Feb;29(1):32-40) 73. Glaessgen A, Busch C, Norberg M, Häggman M, Nilsson B, Egevad L: Prediction of percent Gleason Grade 4/5 by multiple core biopsies. (Scan J Urol Nephrol 2006;40(6):465-71) 74. Miller AM, Egevad L, Lundberg K, Özenci V, Banham AH, Hellström M, Pisa P: CD4+CD25high regulatory T cells are enriched in the peripheral blood and tumor tissue of patients with prostate cancer (J Immunol. 2006 Nov 15;177(10):7398-405) 75. Helpap B, Egevad L: The significance of modified Gleason grading of prostatic carcinoma in biopsy and radical prostatectomy specimens (Virchows Arch. 2006 Dec;449(6):622-7) 76. Helpap B, Egevad L:. Die Wertigkeit des 2005 modifizierten Gleason Grading in der urologischen Diagnostik von Prostatakarzinomen. (Urologe A. 2007 Jan;46(1):59-62) 77. Rydén L, Egevad L, Ekman P, Hellström M: Prevalence of prostate cancer at different levels of serum prostate-specific antigen (PSA) and different free: total PSA ratios in a consecutive series of men referred for prostate biopsies. (Scand J Urol Nephrol. 2007;41(4):302-7) 78. Egevad L, Ehrnström R, Håkansson U, Grabe M: Primary seminal vesicle carcinoma diagnosed at transurethral resection of the prostate. (Urology. 2007 Apr;69(4):778.e11-3.) 79. Travis RC, Key TJ, Allen NE, Appleby PN, Roddam AW, Rinaldi S, Egevad L, Gann PH, Rohrmann S, Linseisen J, Pischon T, Boeing H, Johnsen NF, Tjønneland A, Overvad K, Kiemeney L, Bueno-de-Mesquita HB, Bingham S, Khaw KT, Tumino R, Sieri S, Vineis P, Palli D, Quirós JR, Ardanaz E, Chirlaque MD, Larrañaga N, Gonzalez C, Sanchez MJ, Trichopoulou A, Bikou C, Trichopoulos D, Stattin P, Jenab M, Ferrari P, Slimani N, Riboli E, Kaaks R. Serum androgens and prostate cancer among 643 cases and 643 controls in the European Prospective Investigation into Cancer and Nutrition. (Int J Cancer. 2007 Sep 15;121(6):1331-8) 80. Allen NE, Key TJ, Appleby PN, Travis RC, Roddam AW, Rinaldi S, Egevad L, Rohrmann S, Linseisen J, Pischon T, Boeing H, Johnsen NF, Tjønneland A, Grønbaek H, Overvad K, Kiemeney L, Bueno-de-Mesquita HB, Bingham S, Khaw KT, Tumino R, Berrino F, Mattiello A, Sacerdote C, Palli D, Quirós JR, Ardanaz E, Navarro C, Larrañaga N, Gonzalez C, Sanchez MJ, Trichopoulou A, Travezea C, Trichopoulos D, Jenab M, Ferrari P, Riboli E, Kaaks R: Serum insulin-like growth factor (IGF)-I and IGF-binding protein-3 concentrations and prostate cancer risk: results from the European Prospective Investigation into Cancer and Nutrition. (Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1121-7) 81. Key TJ, Appleby PN, Allen NE, Travis RC, Roddam AW, Jenab M, Egevad L, Tjønneland A, Johnsen NF, Overvad K, Linseisen J, Rohrmann S, Boeing H, Pischon T, Psaltopoulou T, Trichopoulou A, Trichopoulos D, Palli D, Vineis P, Tumino R, Berrino F, Kiemeney L, Bueno-de-Mesquita HB, Quirós JR, González CA, Martinez C, Larrañaga N, Chirlaque MD, Ardanaz E, Stattin P, Hallmans G, Khaw KT, Bingham S, Slimani N, Ferrari P, Rinaldi S, Riboli E: Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study. (Am J Clin Nutr. 2007 Sep;86(3):672-81.) 82. Magnus Hellström, Sara Jonmarker, Janne Lehtiö, Gert Auer and Lars Egevad Proteomics in clinical prostate research (Proteomics Clin Appl, 2007;1:1058-65) 83. Algaba F, Mikuz G, Boccon-Gibod L, Trias I, Arce Y, Montironi R, Egevad L, Scarpelli M, Lopez-Beltran A. Pseudoneoplastic lesions of the testis and paratesticular structures.(Virchows Arch. 2007 Dec;451(6):987-97) 84. Braeckman J, Autier P, Garbar C, Marichal MP, Soviany C, Nir R, Nir D, Michielsen D, Bleiberg H, Egevad L, Emberton M: Computer-aided ultrasonography (HistoScanning): a novel technology for locating and characterizing prostate cancer. (BJU Int. 2008 Feb;101(3):293-8) 85. Johansson M, Appleby PN, Allen NE, Travis RC, Roddam AW, Egevad L, Jenab M, Rinaldi S, Kiemeney LA, Bueno-de-Mesquita HB, Vollset SE, Ueland PM, Sánchez MJ, Quirós JR, González CA, Larrañaga N, Chirlaque MD, Ardanaz E, Sieri S, Palli D, Vineis P, Tumino R, Linseisen J, Kaaks R, Boeing H, Pischon T, Psaltopoulou T, Trichopoulou A, Trichopoulos D, Khaw KT, Bingham S, Hallmans G, Riboli E, Stattin P, Key TJ: Circulating concentrations of folate and vitamin B12 in relation to prostate cancer risk: results from the European prospective investigation into cancer and nutrition study. (Cancer Epidemiol Biomarkers Prev. 2008 Feb;17(2):279-85.) 86. Helpap B, Egevad L: Correlation of Modified Gleason Grading With pT Stage of Prostatic Carcinoma After Radical Prostectomy (Anal Quant Cytol Histol. 2008 Feb;30(1):1-7) 8 87. S Rohrmann, J Linseisen, TJ Key, MK Jensen, K Overvad, N Føns Johnsen, A Tjønneland, R Kaaks, M Bergmann, C Weikert, A Naska, A Trichopoulou, D Trichopoulos, V Pala, HB Bueno-de-Mesquita, A Vrieling, CA González, N Larrañaga, C Navarro, G Hallmans, P Stattin, J Manjer, E Wirfält, L Egevad, P Ferrari, M Jenab, E Riboli: Alcohol consumption and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) (Cancer Epidemiol Biomarkers Prev., 2008; 17(5), 1282-7) 88. Helpap B, Egevad L: Correlation of modified Gleason grading of prostate carcinoma with age, serum prostate specific antigen and tumor extent in needle biopsy specimens (Anal Quant Cytol Histol. 2008 Jun;30(3):133-8) 89. Egevad L: Recent Trends in Gleason Grading of Prostate Cancer (I): Pattern Interpretation (Anal Quant Cytol Histol, 2008 Aug;30(4):190-8) 90. Egevad L: Recent Trends in Gleason Grading of Prostate Cancer (II): Prognosis, Reproducibility and Reporting (Anal Quant Cytol Histol, 2008 Oct;30(5):254-60) 91. Anca Reschner, Helena Harlin, Brett Laven, Fredrik Eriksson, Pavel Pisa, Lars Egevad Expression of immunomodulating genes in prostate cancer and benign prostatic tissue (Anal Quant Cytol Histol, 2009 Apr;31(2):74-82) 92. S Jonmarker, A Glaessgen, WD Culp, P Pisa, R Lewensohn, P Ekman, A Valdman, L Egevad: Expression of PDX-1 in prostatic carcinoma, PIN and benign prostatic tissue (APMIS. 2008 Jun;116(6):491-8) 93. L Egevad, F Algaba, DM Berney, L Boccon-Gibod, D Griffiths, A LopezBeltran, G Mikuz, M Varma, R Montironi: Handling and Reporting of Radical Prostatectomy Specimens in Europe; A Web-Based Survey by The European Network of Uropathology (ENUP) (Histopathology. 2008 Sep;53(3):333-9) 94. Egevad L, Castellanos E, Hellström M, Valdman A: Atypical stromal hyperplasia of the prostate (Scand J Urol Nephrol. 2008;42(5):484-7) 95. Axel Glaessgen, Sara Jonmarker, Anna Lindberg, Bo Nilsson, Rolf Lewensohn, Peter Ekman, Alexander Valdman, Lars Egevad: Heat shock proteins 27, 60 and 70 as prognostic markers of prostate cancer (APMIS, 2008 Oct;116(10):888-95) 96. AJ Evans, PC Henry, T Van der Kwast, D Tkachuk, K Watson, G Lockwood, NE Fleshner, C Cheung, E Belanger, M Amin, L Bocon-Gibod, DG Bostwick, L Egevad, JI Epstein, D Grignon, E Jones, R Montironi, M Moussa, JM Sweet, K Trypkov, T Wheeler, JR Srigley: Interobserver variability between expert urological pathologists for extra-prostatic extension and surgical margin status in radical prostatectomy specimens. (Am J Surg Pathol, 2008 Oct;32(10):150312) 97. M Latour, MB Amin, A Billis, L Egevad, D Grignon, PA Humphrey, VE Reuter, WA Sakr, JR Srigley, TM Wheeler, XJ Yang, JI Epstein: Grading of 9 Invasive Cribriform Carcinoma on Prostate Needle Biopsy: An Interobserver Study among Experts in Genitourinary Pathology (Am J Surg Pathol, 2008 Oct;32(10):1532-9) 98. L Egevad, F Algaba, DM Berney, L Boccon-Gibod, D Griffiths, A LopezBeltran, G Mikuz, M Varma, R Montironi; The ENUP Members: The European Network of Uropathology: A Novel Mechanism for Communication between Pathologists (Anal Quant Cytol Histol, 2009 Apr;31(2):90-5) 99. Rubio CA, Orrego A, Höög A, Porwitz A, Petersson F, Elmberger G, Glaessgen A, Eriksson E, Kanter L, Jaremko G, Egevad L, Laforga J, Liljefors M, Löfdahl B, Norman P, Larsson O, Wanat R, Wejde J, Zickert P, Björk J, Caini S, Palli D, Nesi G: Quantitative assessment of the subepithelial collagen band does not increase the accuracy of diagnosis of collagenous colitis (Am J Clin Pathol. 2008 Sep;130(3):375-81.) 100. Rosenblatt R, Valdman A, Cheng L, Lopez-Beltran A, Montironi R, Ekman P, Egevad L: Endothelin-1 expression in prostate cancer and high-grade PIN (Anal Quant Cytol Histol. 2009 Jun;31(3):137-42.) 101. Lopez-Beltran A, Kirkali Z, Cheng L, Egevad L, Regueiro JC, Montironi R: Targeted therapies and biological modifiers in urologic tumors, pathobiology and clinical implications. (Semin Diagn Pathol, 2008 Nov;25(4):232-44) 102. Egevad L, Håkansson U, Grabe M, Ehrnström R: Urachal signet-cell adenocarcinoma (Scand J Urol Nephrol. 2009;43(1):88-91) 103. Rosenblatt R, Jonmarker S, Lewensohn R, Egevad L, Sherif A, Kälkner KM, Nilsson S, Valdman A, Ullén A: Current status of prognostic immunohistochemical markers for urothelial bladder cancer. (Tumour Biol. 2008;29(5):311-22) 104. Helpap B, Egevad L: Zur klinischen Insignifikanz des Prostatakarzinom. Gibt es morphologische Hinweise? (Urologe A. 2009 Feb;48(2):170-4) 105. R Suzuki, NE Allen, TJ Key, PN Appleby, A Tjønneland, N Føns Johnsen, MK Jensen, K Overvad, H Boeing, T Pischon, R Kaaks, S Rohrmann, A Trichopoulou, M Gesthimani, D Trichopoulos, HB Bueno-de-Mesquita, F van Duijnhoven, C Sacerdote, S Grioni, D Palli, R Tumino, E Ardanaz, J Ramón Quirós, N Larrañaga, MJ Sánchez, MJ Tormo, P Jakszyn, I Johansson, P Stattin, G Berglund, J Manjer, S Bingham, KT Khaw, L Egevad, P Ferrari, M Jenab, E Riboli: A prospective analysis of the association between dietary fiber intake and prostate cancer risk in EPIC (Int J Cancer. 2009 Jan 1;124(1):245-9) 106. Valdman A, Häggarth L, Cheng L, Lopez-Beltran A, Montironi R, Ekman P, Egevad L: Expression of redox pathway enzymes in human prostatic tissue (Anal Quant Cytol Histol, 2009, 31(6):367-) 107. Sui Chu Chung, Peter Hammarsten, Andreas Josefsson , Pär Stattin, Torwald Granfors, Lars Egevad, Anders Bergh, Christopher J. Fowler: A high 10 cannabinoid CB(1) receptor immunoreactivity is associated with disease severity and outcome in prostate cancer. (Eur J Cancer. 2009 Jan;45(1):174-82) 108. Helpap B, Egevad L: Modified Gleason Grading. An Updated Review (Histology and Histopathology, 2009 May;24(5):661-6.) 109. Compérat E, Egevad L, Camparo P, Roupret M, Vaessen C, Valdman A, Jonmarker S, Richard F, Capron F, Cussenot O, Charlotte F: Clinical significance of intratumoral CD8+ regulatory T Treg cells in prostate carcinoma (Anal Quant Cytol Histol, 2010;32(1):39–44) 110. Føns Johnsen N, Tjønneland A, Thomsen BLR, Christensen J, Loft S, Friedenreich C, Key T, Allen N, Lahmann PH, Overvad K, Kaaks R, Rohrmann S, Boing H, Misirli G, Trichopoulou A, Zilis D, Tumino R, Pala V, Bueno-deMesquita HB, Kiemeney LA, Gonzales C, María J, Manjer J, Wirfält E, Khaw KT, Wareham N, Boffetta P, Egevad L, Rinaldi S, Riboli E: Physical activity and risk of prostate cancer in the European Prospective - Investigation into Cancer and Nutrition (EPIC) cohort. (Int J Cancer. 2009 Feb 3. [Epub ahead of print]) 111. M Augsten, C Sundquist, E Olsson, C Stolz, P Tsagozis, T Levchenko, MJ Frederick, Å Borg, L Egevad, P Micke, A Östman: CXCL14 produced by cancer- associated fibroblasts is a multi-modal stimulator of prostate tumor growth (Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3414-9) 112. Egevad L, Montorsi F, Montironi R: Donald F. Gleason (1920-2008). (Eur Urol, 2009 Feb 5. [Epub ahead of print]) 113. FL Büchner, HB Bueno-de-Mesquita, MM Ros, E Kampman, L Egevad, K Overvad, O Raaschou-Nielsen, A Tjonneland, N Roswall, F Clavel-Chapelon, J Chang-Claude, R Kaaks, H Boeing, S Weikert, A Trichopoulou, F Berrino, P. Vineis, R Tumino, S Panico, A Vrieling, PHM Peeters, E Lund, IT Gram, C Martinez, CA Gonzalez, G Berglund, G Hallmans, B Ljungberg, TJ Key, AW Roddam, S Bingham, N Slimani, L.A.L.M Kiemeney, E Riboli: Consumption of vegetables and fruit and the risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition (Int J Cancer. 2009 Dec 1;125(11):264351) 114. John R. Srigley, Peter A. Humphrey, Mahul B. Amin, Sam S. Chang, Lars Egevad, Jonathan I. Epstein, David J. Grignon, James M. McKiernan, Rodolfo Montironi, Andrew A. Renshaw, Victor E. Reuter, Thomas M. Wheeler: Protocol for the Examination of Specimens From Patients With Carcinoma of the Prostate Gland (Archives of Pathology and Laboratory Medicine, 2009 Oct;133(10):1568-76) 115. Jonmarker Jaraj S, Camparo P, Boyle H, Germain F, Nilsson B, Petersson F, Egevad L. Intra- and interobserver reproducibility of interpretation of immunohistochemical stains of prostate cancer. (Virchows Arch. 2009 Sep 18) 11 116. Antonio Lopez-Beltran, Rodolfo Montironi, Lars Egevad, Maria T Caballero-Vargas, Marina Scarpelli, Ziya Kirkali, Liang Cheng: Genetic profiles in renal tumors. (Int J Urol. 2010 Jan;17(1):6-19. Epub 2009 Oct 13) 117. Hammarsten P, Karalija A, Josefsson A, Rudolfsson SH, Wikström P, Egevad L, Granfors T, Stattin P, Bergh A. Low levels of phosphorylated epidermal growth factor receptor in nonmalignant and malignant prostate tissue predict favorable outcome in prostate cancer patients. Clin Cancer Res. 2010 Feb 15;16(4):1245-55. Epub 2010 Feb 9 118. A-E Carsin, F J Drummond, A Black, P.J van Leeuwen, L Sharp, LJ Murray, D Connolly, L Egevad, M Boniol, P Autier, H Comber, A Gavin: Impact of PSA testing and prostatic biopsy on cancer incidence and mortality: comparative study between the Republic of Ireland and Northern Ireland. (Cancer Causes Control. 2010 Jun 1. [Epub ahead of print]) 119. Alexander Valdman, Sara Jonmarker Jaraj, Eva Compérat, Fréderic Charlotte, Morgan Roupret, Pavel Pisa, Lars Egevad: Distribution of Foxp3, CD4 and CD8 positive lymphocytic cells in benign and malignant prostate tissue (Apmis, 2010 May;118(5):360-5) 120. Sara Jonmarker Jaraj, Lars Egevad: Formalin Fixation and Immunoreactivity in Prostate Cancer and Benign Prostatic Tissue (Apmis, 2010 May;118(5):383-8) 121. Benny Holmström,, Erik Holmberg, Lars Egevad, Jan Adolfsson, JanErik Johansson, Jonas Hugosson, and Pär Stattin on behalf of the National Prostate Cancer Register (NPCR) of Sweden: Primary vs. Deferred Radical Prostatectomy in The National Prostate Cancer Register (NPCR) of Sweden (accepted, J Urol) 122. A Lopez-Beltran, F Algaba, DM Berney, L Boccon-Gibod, P Camparo, D Griffiths, , G Mikuz, R Montironi, M Varma, L Egevad; Handling and Reporting of Transurethral Resection Specimens of the Bladder in Europe: A Web-Based Survey by the European Network of Uropathology (ENUP) (Histopathology, 2011 Mar;58(4):579-585) 123. Gouas DA, Shi H, Hautefeuille AH, Ortiz-Cuaran SL, Legros PC, Szymanska KJ, Galy O, Egevad LA, Abedi-Ardekani B, Wiman KG, Hantz O, Caron de Fromentel C, Chemin IA, Hainaut PL: Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein. (Carcinogenesis. 2010 Aug;31(8):1475-82. Epub 2010 Jun 10) 124. F.L. Büchner, H.B. Bueno-de-Mesquita, M.M. Ros, E. Kampman, L. Egevad, K Overvad, A Tjønneland, N Roswall, F Clavel-Chapelon, M-C Boutron-Ruault, M Touillaud, R Kaaks J Chang-Claude, H Boeing, S Weikert, A Trichopoulou , A Naska , V Benetou , D Palli, S Sieri, P. Vineis, R Tumino, S Panico, FJB van Duijnhoven, PHM Peeters, CH van Gils, E Lund, I.T. Gram, M-J Sánchez , P Jakszyn, N Larrañaga, E Ardanaz, C Navarro, L Rodríguez, J 12 Manjer, R Ehrnström, G Hallmans, B Ljungberg, TJ Key , NE Allen , K-T Khaw, N Wareham, N Slimani, M Jenab, P Boffetta, L.A.L.M Kiemeney, E Riboli: Variety in vegetable and fruit consumption and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition (Int J Cancer, 2011 15;128(12):2971-9) 125. Stattin P, Holmberg E, Johansson JE, Holmberg L, Adolfsson J, Hugosson J; National Prostate Cancer Register (NPCR) of Sweden. Outcomes in localized prostate cancer: National Prostate Cancer Register of Sweden follow-up study. J Natl Cancer Inst. 2010 Jul 7;102(13):950-8. Epub 2010 Jun 18. 126. Johansson A, Rudolfsson S, Hammarsten P, Halin S, Pietras K, Jones J, Stattin P, Egevad L, Granfors T, Wikström P, Bergh A. Mast Cells Are Novel Independent Prognostic Markers in Prostate Cancer and Represent a Target for Therapy. Am J Pathol. 2010 Aug;177(2):1031-41. Epub 2010 Jul 8. 127. Lars Egevad , Alexander Valdman , N Peter Wiklund , Pascal Sève , Charles Dumontet: Beta Tubulin III Expression in Prostate Cancer (Scan J Urol Nephrol, 2010 Dec;44(6):371-7) 128. Lars Egevad, John R Srigley and Brett Delahunt: International Society of Urological Pathology (ISUP) consensus conference on handling and staging of radical prostatectomy specimens: rationale and organization (Mod Pathol 2011; 24: 1-5) 129. Hemamali Samaratunga, Rodolfo Montironi, Lawrence True, Jonathan Epstein, Peter Humphrey, Theo van der Kwast, Thomas Wheeler, Brett Delahunt, John Srigley, Lars Egevad, The ISUP prostate consensus group:International Society of Urological Pathologists (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working Group 1: Handling of The Specimen (Mod Pathol 2011; 24: 6-15) 130. Theo van der Kwast, Mahul Amin, Athanase Billis, Jonathan Epstein, David Griffiths, Peter Humphrey, Rodolfo Montironi, Thomas Wheeler, John Srigley, Lars Egevad, Brett Delahunt, The ISUP prostate consensus group:International Society of Urological Pathologists (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working Group 2: pT2 Tumors and Tumor Volume (Mod Pathol 2011; 24: 1625) 131. Cristina Magi-Galuzzi, Andrew Evans, Jonathan Epstein, Theo van der Kwast, Rodolfo Montironi, Thomas Wheeler, Brett Delahunt, John Srigley, Lars Egevad, Peter Humphrey, The ISUP prostate consensus group: International Society of Urological Pathologists (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working Group 3: Extraprostatic Extension and Microvessel Invasion (Mod Pathol 2011; 24: 2638) 132. Daniel Berney, Thomas Wheeler, David Grignon, Jonathan Epstein, David Griffiths, Peter Humphrey, Theo van der Kwast, Rodolfo Montironi, Brett 13 Delahunt, Lars Egevad, John Srigley, The ISUP prostate consensus group: International Society of Urological Pathologists (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working Group 4: Seminal Vesicles and Lymph Nodes (Mod Pathol 2011; 24: 39-47) 133. Puay Hoon Tan, Liang Cheng, Peter Humphrey, Theo van der Kwast, Rodolfo Montironi, Thomas Wheeler, Brett Delahunt, John Srigley, Lars Egevad, Jonathan Epstein, The ISUP prostate consensus group: International Society of Urological Pathologists (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working Group 5: Surgical Margins (Mod Pathol 2011; 24: 48-57) 134. Lina Thors, Anders Bergh, Emma Persson, Peter Hammarsten, Pär Stattin, Lars Egevad, Torvald Granfors, Christopher J. Fowler: Fatty acid amide hydrolase expression in prostate cancer: association with disease severity and outcome, cannabinoid receptor-1 expression and regulation by interleukin-4 (PLoS ONE, 2010 Aug 19;5(8)) 135. Sara Jonmarker Jaraj, Martin Augsten, Lars Häggarth, Kenneth Wester, Fredrik Pontén, Arne Östman, Lars Egevad: GAD1 is A Novel Prostate– Specific Tissue Biomarker (Scand J Urol Nephrol, 2011 Feb;45(1):39-45. Epub 2010 Nov 22.) 136. Lars Häggarth, Christina Hägglöf, Sara Jonmarker Jaraj, Kenneth Wester, Fredrik Pontén, Arne Östman, Lars Egevad : Diagnostic Biomarkers of Prostate Cancer (Scand J Urol Nephrol, 2011 Feb;45(1):60-7. Epub 2010 Nov 1) 137. Carlos A Gonzalez , Leila - Lujan Barroso, Martine M Ros, H Bas Buenode-Mesquita, Nina Roswall, Anne M Tjonneland, Frederike L Buchner, Lars Egevad, Kim Overvad, Ole Raaschou-Nielsen, Francoise Clavel-Chapelon, Marie-Christine Boutron-Ruault, Marina S Touillaud, J Chang-Claude, Naomi E Allen, Lambertus A Kiemeney, Timothy J Key, Rudolf Kaaks, Heiner Boeing, Steffen Weikert, Antonia Trichopoulou, E Oikonomou, Dimosthenis Zylis, Domenico Palli, Franco Berrino, Paolo P Vineis, Rosario Tumino, Amalia Mattiello, Alina Vrieling, Petra H.M. Peeters, Christine L Parr, Inger Torhild Gram, Guri Skeie, Maria-Jose Sanchez, Nerea Larrañaga, Eva Ardanaz, Carmen Navarro, Laudina Rodriguez, David Ulmert, Roy Ehrnstrom, Göran Hallmans, Borje Ljungberg, Andrew Wilfred Roddam, Sheila A Bingham, Kay-Tee Khaw, Nadia Slimani, Paolo A Boffetta, Mazda Jenab, Traci Mouw, Dominique S Michaud, Elio Riboli: Red meat, dietary nitrosamines and heme iron and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) (Cancer Epidemiology, Biomarkers & Prevention) 138. Marcus Thomasson , Baofeng Wang, Peter Hammarsten, Anna Dahlman, Jenny Liao Persson, Andreas Josefsson, Pär Stattin, Torvald Granfors, Lars Egevad, Roger Henriksson, Anders Bergh, and Håkan Hedman LRIG and the liar paradox in prostate cancer: A study of the expression and clinical significance of LRIG1 in prostate cancer (Int J Cancer. 2011 Jun 15;128(12):2843-52) 14 139. Jakszyn P, González CA, Luján-Barroso L, Ros MM, Bueno-deMesquita HB, Roswall N, Tjønneland AM, Büchner FL, Egevad L, Overvad K, Raaschou-Nielsen O, Clavel-Chapelon F, Boutron-Ruault MC, Touillaud MS, Chang-Claude J, Allen NE, Kiemeney LA, Key TJ, Kaaks R, Boeing H, Weikert S, Trichopoulou A, Oikonomou E, Zylis D, Palli D, Berrino F, Vineis P, Tumino R, Mattiello A, Peeters PH, Parr CL, Gram IT, Skeie G, Sánchez MJ, Larrañaga N, Ardanaz E, Navarro C, Rodríguez L, Ulmert D, Ehrnström R, Hallmans G, Ljungberg B, Roddam AW, Bingham SA, Khaw KT, Slimani N, Boffetta PA, Jenab M, Mouw T, Michaud DS, Riboli E. Red meat, dietary nitrosamines, and heme iron and risk of bladder cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cancer Epidemiol Biomarkers Prev. 2011 Mar;20(3):555-9. Epub 2011 Jan 14. 140. Chargari C, Comperat E, Magné N, Védrine L, Houlgatte A, Egevad L, Camparo P. Prostate needle biopsy examination by means of virtual microscopy. 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Key elements in structured histopathology reporting of radical prostatectomy specimens. Pathology. 2011 Aug;43(5):410-9. 152. Josefsson A, Adamo H, Hammarsten P, Granfors T, Stattin P, Egevad L, Laurent AE, Wikström P, Bergh A. Prostate cancer increases hyaluronan in surrounding nonmalignant stroma, and this response is associated with tumor growth and an unfavorable outcome. Am J Pathol. 2011 Oct;179(4):1961-8. Epub 2011 Aug 18. 153. Talvitie H, Aström K, Larsson O, Ahlén J, Bergh A, Egevad L. Solitary fibrous tumor of the prostate: a report of two cases. Pathol Int. 2011 Sep;61(9):536-8. doi: 10.1111/j.1440-1827.2011.02696.x. Epub 2011 Aug 1. 154. Egevad L. Handling of radical prostatectomy specimens: total or partial embedding? Histopathology. 2011 Nov;59(5):1011-2; author reply 1012-3. 155. Liu W, Lindberg J, Sui G, Luo J, Egevad L, Li T, Xie C, Wan M, Kim ST, Wang Z, Turner AR, Zhang Z, Feng J, Yan Y, Sun J, Bova GS, Ewing CM, Yan G, Gielzak M, Cramer SD, Vessella RL, Zheng SL, Grönberg H, Isaacs WB, Xu J. Identification of novel CHD1-associated collaborative alterations of genomic structure and functional assessment of CHD1 in prostate cancer. Oncogene. 2011 Dec 5. [Epub ahead of print] 16 17 156. Algaba F, Delahunt B, Berney DM, Camparo P, Compérat E, Griffiths D, Kristiansen G, Lopez-Beltran A, Martignoni G, Moch H, Montironi R, Varma M, Egevad L. Handling and reporting of nephrectomy specimens for adult renal tumours: a survey by the European Network of Uropathology. J Clin Pathol. 2012 Feb;65(2):106-13. Epub 2011 Sep 30. 157. Liu W, Lindberg J, Sui G, Luo J, Egevad L, Li T, Xie C, Wan M, Kim ST, Wang Z, Turner AR, Zhang Z, Feng J, Yan Y, Sun J, Bova GS, Ewing CM, Yan G, Gielzak M, Cramer SD, Vessella RL, Zheng SL, Grönberg H, Isaacs WB, Xu J. 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