How similar are traits of offspring to those of their parents? Part A. Determining Parent Phenotypes Names: 1. Examine the models of 8 chromosomes on the chromosome sheet. Four of the chromosomes are from the Mother and four are from the Father. Chromosomes of equal length & color are to be considered homologs or homologous chromosomes. The "Mother" originally got her chromosomes from her parents (1 of each chromosome from her mom and 1 of each chromosome from her dad). The same is true for the "Father." 2. Use a pair of scissors to cut out the 8 chromosomes. OR (drag & drop) them into a new document. Manipulate the page sizes so you may toggle between pages on the same screen. 3. Make sure that the homologs are next to each other. For example with the mother, the 2 long pink chromosomes should be side by side, and the 2 short pink ones should be side by side. Do the same for the "Father's" blue chromosomes. 4. To determine the phenotypes, or physical characteristics, that are passed on, we need to look at homologous chromosomes to find the alleles that make up the genotype, or type of genes. 5. The letters written on each chromosome stand for alleles of the same gene. Examine Table 1 below. It shows what traits are represented by the letters. 6. Complete Table 2 for the phenotypes of both the mother and father. Describe the nine different phenotypes for each parent based on the alleles present on their chromosomes. Long chromosomes have the first 5 traits, short have the last 4 traits. TABLE 1 Allele F B G E R T H D C Phenotype six fingers black hair gap between front teeth free or detached earlobes Rh positive blood can roll tongue mid-digital hair skeleton of average height presence of Huntington’s disease Allele f b g e r t h d c Phenotype five fingers blonde hair no gap between front teeth attached earlobes Rh negative blood cannot roll tongue no mid-digital hair skeleton development- dwarfism absence of Huntington’s disease Part B: Determining Children's Phenotypes 1. Place the 4 Mother chromosomes face down on the right side of your desk. Or at the top of a new page. 2. Place the 4 Father chromosomes face down on the left side of your desk. Or at the bottom of a new page. 3. RANDOMLY pick 1 long chromosome from the father's pile and 1 long chromosome from the mother's pile. Then pick 1 short chromosome from each parent’s pile. This simulates chromosomes that are passed to the 1st child during fertilization. 4. Turn the chromosomes over. Read the allele combinations for the 1st child and decide which phenotypes they correspond to. Record the genotypes and phenotypes for the 1st child in table 2, labelled 1st child. 5. Repeat steps 1-4 two more times to simulate the chromosomes passed to a 2nd and 3rd child. 6. Draw a picture of your family. : o) and complete the questions and conclusions section on the answer sheet. Chromosome Sheet: Work Space to Drag and Drop Below...or work on a new page. Mother’s Chromosomes Father’s Chromosomes F f t t b b h h H H f G e eR b f g g B E Er g g e e R D c T h h d c t H g g e e r D C d c Lab Investigation Answer Sheet Name: for online submission: only submit this page with its answers. Table 2 Trait Father Mother phenotypes phenotypes 1st child genotype phenotype 2nd child genotype phenotype 3rd child genotype phenotype # of fingers (6/5) hair (black/blonde) gap in teeth (y/n) earlobes (free/attached) Rh type (+/-) tongue roll (y/n) mid-digit hair (y/n) height (norm/dwarf) Huntington’s (y/n) Questions: 1. In this simulation, how many chromosomes did each child receive from each parent? (**) 2. In humans, how many chromosomes would a child normally get from each parent? (**) 3. Explain how the element of chance enters into the inheritance of traits. (Hint: Mendelian Laws) (**) 4. Using data you generated for the 1st child, determine the number of physical characteristics inherited from only the father (**) or from only the mother (**). 5. Using data you generated for the 2nd child, determine the number of physical characteristics inherited from only the father (**), the mother only (**), and the number of traits in common with the 1st child (**). 6. Using data you generated for the 3rd child, determine the number of physical characteristics inherited from only the father (**), the mother only (**), the number of traits in common with the 1st child (**), and the number of traits in common with the 2nd child (**). Conclusion Essay: How similar are traits of each offspring to those of their parents and each other? In other words, compare and contrast each child to each other and to their parents. (**)