Inheritance 1- Variation 1- (G)State what is meant by “species” 2- (G) State the name of changes which can observed between members of a same species 3-(C) Explain what is meant by continuous and discontinuous variation. (G) Give examples of continuous and discontinuous variation How is discontinuous variation usually represented? How is continuous variation usually represented? Organisms who could interbreed to produce fertile offspring. These changes are known as “variation” Discontinuous: - clear-cut differences in features - can be put in distinct groups separated by “or” . E.g. Tongue rolling, handedness, blood groups, ear lobe types. → bar-chart. Continuous: - no distinct groups - gradual changes in features (range of values spanning from one extreme to another with most organisms in the middle). E.g. Height, weight. → histogram: bell shaped line graph can be drawn from histogram: normal distribution curve. Inheritance 2- What is inheritance? 1- (G) State from where organisms’ characteristics come from. Give examples for animals and plants. Some are inherited from our parents. Humans: Tongue rolling, eye colour, hair colour. Other animals: Fur colour, eye colour. Plants: Flower colour, leaf shape, seed shape. Remainder of our characteristics determined by our environment and life style (e.g. weight). 2- (G) State what genes are. 3- (G) State what controls a characteristic (e.g. type of ear lobe, blood group, height) 4- (C) State the name given to the different forms of a gene 5- (G) State how many matching sets of chromosomes are found in a body cell 6- (G) State from where the two forms of a genes come from 7- (G) State the meaning of homozygote (1) and heterozygote (2). Genes are parts of chromosomes Inherited characteristics are controlled by the two forms of a gene. Alleles Two Each parent contributes one of the two forms. (1) Organism with 2 identical alleles for one gene (2) Organism with 2 different alleles for one gene 1 8- (G) What sex cells called? 9- (G) State how many forms of a gene is carried by individual sex cell. 10- (G) State how many sets of chromosomes are found in a sex cell. 11- (G) State when this reduction from two sets to one set takes place. 12- (G) Describe how a complete set of chromosomes is achieved at fertilisation. Monohybrid cross 1- Explain what is meant by phenotype. (G) Identify examples of phenotypes of the same characteristic. Explain what is meant by genotype. 2- (G) Explain what true breeding is. 3- (G) Explain what a dominant allele is. 4- (G) Explain what a recessive phenotype is. Gametes. Male gamete: sperm cell, pollen grain in plants Female gamete: egg cell or ovum. One One set of chromosome During gamete formation Male gamete fuses with female gamete forming a zygote with 2 sets of chromosomes. Phenotype: the external expression of a feature controlled by one or more genes. Examples of phenotypes for the same characteristic: Hair colour: blond, brown, red Ability to roll tongue: roller, non-roller Seed shape: round, wrinkled Genotype: the two alleles of a gene carried by an organism. Often presented as a pair of alleles. Organism has identical alleles for a particular feature: it is a homozygous for this feature An allele which phenotype shows, i.e. a stronger allele. An allele which phenotype does not show when the other allele is dominant. 5- (G) Identify examples of truebreeding, dominant and recessive characteristics from the number and phenotypes of given crosses. See other resources 6- (C) Explain what is meant by a monohybrid cross. 7- (G) Identify using letters the successive generations of a cross. 8- (G) State what is the phenotype of the first generation of a monohybrid cross. 9- (C) Predict the proportion of the phenotypes of the second generation of a monohybrid cross. True-breeding parents for different phenotypes produce offspring. Parents: P First generation: F1 Second generation: F2 All F1 organisms have the same phenotype; They are said to be uniform. A ratio of 3:1 3 showing dominant phenotype. 1 showing recessive phenotype. 2 10- (C) Explain monohybrid crosses in terms of the genotype E.g. Pea plant height: T: tall Parent (P) TT F1 F1 cross F2 11- (C) Explain differences between observed and predicted figures in monohybrid crosses. 12- (G) State what determines the sex of a child. 13- (G) State the difference in chromosomes between boy and girls. 14- (G) Explain how the sex of a child is determined with reference to the X and Y chromosome. Tt X Tt T t TT Tt tt and t: dwarf X Tt T Tt t T t T TT Tt t Tt tt tt - random nature of fertilisation - death of embryo – death of seedlings Sex chromosomes: X and Y chromosomes Boy: one X and one Y chromosome Girl: two X chromosome The female gamete can only contribute with an X chromosome. Therefore, it is the gamete from the father (X or Y) which will determine the child’s sex. Inheritance 3- Genetics and society 1- (G&C) Describe two examples, one plant (1), one animal (2), of the enhancement of a characteristic through selective breeding. 3- (G) Describe an example of a human condition caused by a chromosome mutation e.g. Down’s syndrome. 4- (C) Give an example of a chromosome mutation advantageous to humans, in a plant or animal of economic importance. 5- (C) What is a mutagenic agent? Give an example. 6- (G) State what can be used to detect chromosome mutations (1) Crop yield per acre in cereals (2) Race horse, Milk yield, Bacon Weight Down’s Syndrome is a condition caused by one pair of chromosome which fails to separate during gamete formation. As the result, after fertilisation, the zygote has 3 copies of chromosomes 21. In bacteria: digest oil → used to clean oil spills. In a plant: agricultural wheat has more chromosomes than wild wheat. The mutated wheat has higher yield. A mutagenic agent or mutagen is a factor which can change the structure of a chromosome. Mutagens are for example: X-rays, ultra-violet, radiations from radioactive material. Amniocentesis: a sample is taken from the amniotic fluid. Cells allowed to divide and photographed. Chromosomes arranged in pairs and compared to other pictures to detect anomaly in chromosome number. 3 4