Meiosis, Sex Cells, Sexual Reproduction Skeleton Notes Introduction: In higher organisms, plants and animals, individuals have two copies of every chromosome and are referred two as a Diploid (2n) “double set” individual. In humans the diploid #=46 (23 pairs). One set of each pair of chromosomes is inherited from the mother and the other set from the father. In sexual reproduction, the two partners produce gametes which are joined to produce an offspring. However, two problems must be solved in sexual reproduction. How does the joining of two reproductive cells (gametes) occur without doubling the amount of chromosomes? How can the chromosome number be reduced by half so that the number of chromosomes does not increase with each generation of reproduction? The answer- MEIOSIS. Objectives: Differentiate between Mitosis and Meiosis Model the events of meiosis, accentuating the major differences between Mitosis and Meiosis. Explain the importance of “Crossing Over” in the context of genetic variability. Notes Overview: Meiosis is a form of cell division in which there are ______successive cell divisions. In meiosis a _________ cell with ( ) or “double set” of chromosomes is reduced to four ___________ cells with ( ) or “single set” of chromosomes. In humans, the diploid number=______, the haploid number = ______ One chromosome represents 100’s of 1000’s of genes each gene is specific to an area on the DNA molecule Meiosis occurs in our germative cells which are regular body (diploid) cells that produce our ____________ The germative cell in females is the __________ which produces ______. The germative cell in males is the ___________ which produces _______. Why do We need Meiosis? The process of meiosis guarantees the chromosomal number remains stable from one generation to the next during __________ _______________. from mom from dad child too much muc h! Meiosis reduces genetic content by _________ __________ _____________________ ___________ ____________ _____________________ ______________________ Homologous Chromosomes: The 46 chromosomes are actually _________ pairs of chromosomes. The members of each pair are called ______________ because they are similar in genetic content. The chromosomes are equivalent and contain the same kinds of __________ arranged in the same order. They may have different versions of genes or “_____________” because they come from different parents. In contrast to Mitosis, in Meiosis homologous chromosomes _________ prior to cell division forming a grouping of four __________________ known as Tetrad During meiosis I ____________ __________ separate and therefore different _________ also separate During Meiosis II individual chromatids separate MEIOSIS During meiosis, three important things occur that did not occur in mitotis: 1. _______________ pair up forming _______________ pairs of chromosomes. Metaphase of Mitosis Metaphase of Meiosis I Chromosomes line up individually along the equatorial plane Chromosomes pair up prior to division forming Homologous pairs of chromosomes 2. Homologous chromosomes exchange genetic information in an event called ______________ _______________. PROPHASE I Crossing Over Occurs during _____________ of meiosis I This process generates __________ by reordering the _____________ of genes within homologous chromosomes The resulting chromatids have _______ that is unique or recombinant. A A B B C b C c D D E F a a d E F e f A A B b c C a a B b c b C c D D d E e f F d E F e d e f f The result of “Crossing-over” is ______________ DNA. DNA with unique genetic make-up from two different chromosomes. 3. The newly scrambled chromosomes separate and go into _____ different daughter cells so that each new cell contains only ______ chromatid of each pair of homologous chromosomes. Paired Homologous Chromosomes separate Meiosis I Meiosis II Diploid germ cell Sister chromatids separate Haploid gametes Mitosis vs. Meiosis Mitosis Meiosis Responsible for growth, repair, and division in primitive unicellular life forms. Occurs only in diploid cells and produces only haploid daughter cells. The nucleus divides twice producing four nuclei. Occurs in body cells and produces identical daughter cells having the diploid (2n) number of chromosomes. The daughter cells are clones (genetically identical) to the parent cell Each haploid chromosome is a new combination of old chromosomes because of crossing over The chromosomes replicate only once, so each nucleus contains half of the number of chromosomes (Haploid Chromosome). Stages of Meiosis: Prophase I Early Prophase: Describe Late Prophase: Describe Metaphase I Describe: Anaphase I Describe: Telophase I Describe: Cytokinesis: Meiosis II Daughter cell From Meiosis I Sister chromatids carry the same genes but may contain different versions Gene Homolog- (chromatid of a homologous chromosome) Meiosis II produces gametes with ___ copy of each chromosome called a ___________ and thus ____ copy of each gene. Describe: Metaphase II of Meiosis Describe: Anaphase II of Meiosis Describe: Telephase II of Meiosis Describe: Results of Meiosis and Cytokinesis Each of these four cells is called a _________________ The cells are _______________ because they contain half the genetic material as the parent cell. Each cell has _________ copy of each original ________________. Each chromosome has one ___________ or version of each gene There may be different combinations of ___________ for different genes depending the extent of ___________ ______________ that occurred in Prophase I of meiosis.