OLIVE VIEW - UCLA EDUCATION & RESEARCH INSTITUTE 2006 - 2007 Annual Report OLIVE VIEW-UCLA MEDICAL CENTER EDUCATION & RESEARCH INSTITUTE BOARD OF TRUSTEES 2006 - 2007 President and Chair: Andrew Wong, M.D. Medicine 2B182 Extension 3205 President-elect and Vice-Chair: Paul Schmit, M.D. Surgery 2B156 3194 Medical Director and Exec. Secretary: William Loos, M.D. Med Admin 2C138 3205 Treasurer: Paul Liu, M.D. Pathology 1A140 4033 Hospital Administration: Melinda Anderson / Gretchen McGinley Hospital Administration 2C155 3001 Service Chiefs: Rima Matevosian, M.D. - Anesthesiology 3A113 David Talan, M.D. - Emergency Medicine New Doctors Building Dennis Cope, M.D. - Medicine 2B172 Alan Shewmon, M.D. - Neurology Christine Holschneider, M.D. - OB-GYN (Acting) **Paul Liu, M.D. – Pathology, 1A140 Mohammad Malekzadeh, M.D. - Pediatrics 3A108 Santwant Sidhu, M.D., Primary Care & Comm. - North Annex Alex Kopelowicz, M.D. - Psychiatry 6D Ramesh Verma, M.D. - Radiology & Nuclear Med. 1A140 Jesse Thompson, M.D. - Surgery 2B156 4350 3110 3205 3242 3222 4033 3233 3630 3432 4078 3194 Director of Nursing: Marci Hamilton - Nursing 2C197 3156 Six Elected Members: Adel El-Bialy, M.D., Cardiology/Med Lester Jones, M.D., Surgery, 2B156 Leland Powell, M.D., Med 2B182 Maureen Simms, M.D., Pediatrics, 3A108 Robin Wachsner, M.D., Cardiology/Med Soma Wali, M.D., Med 2B182 (2006-2009) (2005-2008) (2004-2007) (2005-2008) (2006-2009) (2004-2007) 4289 3194 3205 3233 4289 3205 UCLA Medical Faculty Board Trustee - Inactive Past President Fredrick Abrahamian, D.O., Emer Med, North Annes 3110 ERI Administration: Denise Tritt 3434 July 1, 2006 Revised 04/01/07 TABLE OF CONTENTS Executive Summary Annual Audit Business Office Conferences Indirect Costs Institutional Review Board Personnel Research Awards Revenue Scientific Misconduct Appendices Board of Trustees - Treasurer’s Report ERI Committee Lists Overhead & Rate Data Sheet Page Page Page Page Page Page Page 1 2 2 2 3 4 4 Page 5 Page 9 Page 9 Page 10 EXECUTIVE SUMMARY The Olive View-UCLA Education & Research Institute, Inc. entered into a Medical Research Agreement with Los Angeles County in 1981, which allowed members of the ERI to conduct research and educational activities on the Olive View Medical Center’s premises. The Medical Research Agreement provides that ERI shall “...seek contracts, donations, and non-County funded grants to conduct medical research and medical education projects at Hospital and in area.” The ERI allows physicians and related health-care personnel to engage in medical research in two main areas: through federal and/or non-profit funded research and clinical trials. At the same time, the past few years have seen an increase in the level of CME funds administered through the ERI due to California Medical Association accreditation requirements. The ERI oversees all research conducted at Olive View-UCLA Medical Center and all ValleyCare sites. The purpose of the ERI is to stimulate professional and scientific contributions by the members of the medical staff and to provide facilities and personnel for the performance of medical research and education. The ERI is governed by the Board of Trustees which consist of officers, ex-officio members, department chairs and six elected members. The Officers of the ERI include Andrew Wong, M.D., President, Paul Schmit, M.D., President Elect, Paul Liu, M.D., Treasurer, and William Loos, M.D, Secretary, The Olive View-UCLA ERI’s Institutional Review Board (IRB) assures that all research is conducted in accordance with federal, state, and county rules and regulations. The IRB committee members complete training in human subjects and HIPAA regulations related to research as a requirement of committee membership. The ERI also obtains and negotiates grants and contracts with private, for-profit and government sponsors. Sponsored research, clinical trial contracts, and other grants continue to be administered through the ERI Business Office under the direction of the Business Manager. New clinical studies are negotiated with the Business Manager and outside legal counsel. Finances (including monthly reports to PI’s, quarterly reports to the Finance Committee, and the annual audit) continue to be managed by the Accountant. Funds managed by the ERI pay direct costs (including salary, benefits, equipment and supplies) and indirect costs. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 1 ANNUAL AUDIT The annual audit of the ERI was conducted in September 2006 by the firm of Kaplan, Lim and Brignoni. The final audit report stated that all financial statements were in order and that the ERI is in compliance with federal OMB Circular A-133. BUSINESS OFFICE The monthly dollar amount of payables decreased 18% from the previous fiscal year. It is noted that fiscal years 2004-2005 and 2005-2006 included unusually large, one-time payments which inflated the annual total. Compared to fiscal year 2003-2004, the monthly dollar amount of payables decreased slightly by 4%. Listed below is a comparison of the dollar amount of monthly payables since the 2003-2004 fiscal year. PAYABLES (BY MONTH) $85,220 2006 - 2007 $103,910 2005 - 2006 $128,826 2004 - 2005 $88,496 2003 - 2004 $0 $20,000 $40,000 $60,000 $80,000 $100,000 $120,000 $140,000 CONFERENCES The Department of Emergency Medicine sponsored three national conferences last year. All three conferences included lectures addressing topics in infectious disease, pediatrics, primary care, OB-Gyn, toxicology, and critical care for emergency physicians and other health care providers. Optional afternoon interactive ECG and emergency medicine board recertification courses were offered at all conferences. The first conference, entitled “19th Annual Olive View-UCLA National Conference on Advances in Emergency Medicine and Primary Care,” was held in Las Vegas, Nevada in April 2006. Approximately 200 people attended. The second conference, entitled “19th Annual Olive View-UCLA National Conference on Advances in Emergency Medicine and Primary Care,” was held in Coronado, California in July 2006. Approximately 250 people attended. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 2 The third conference, entitled “19th Annual Olive View-UCLA National Conference on Advances in Emergency Medicine and Primary Care,” was held in Boston, Massachusetts in October 2006. Approximately 200 people attended. INDIRECT COSTS The ERI’s indirect cost rates are as follows: Investigator Generated Protocols Industry Sponsored Clinical Trials Education/Service Programs Continuing Medical Education Gifts 21% MTDC 25% TDC 20% MTDC 15% TDC 5% Revenue The overhead rate was successfully negotiated with DHS. The approved established rate is 21%. The chart below shows the ERI's overhead revenue by type of funding source. The five categories of revenue are Federal/State/Local Contracts & Grants; Clinical Trials, For Profit Contracts & Grants, Various Research and Patient Service Funds. 2004-2005 2005-2006 2006-2007 Federal/State/Local C&G $135,894 $145,423 $174,241 Clinical Trials $82,872 $31,475 $58,687 For Profit C&G $51,305 $73,102 $50,404 Various Research $9,743 $17,302 $3,873 $522 $2,594 -$1,539 Patient Service Funds Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 3 INSTITUTIONAL REVIEW BOARD Institutional Review Board: In 2006-2007, the amount of new projects reviewed by the committee slightly decreased (1%). The number of renewals increased by 32% and deactivated projects decreased slightly by 8%. Below is a summary of activity for the past four years: New Projects Renewals Deactivated 2003 - 2004 2004 - 2005 2005 - 2006 2006 - 2007 37 34 34 34 31 28 33 41 26 35 50 19 All principal investigators and key personnel are required to receive human subject and HIPAA training regardless of funding source. Training is available through the ERI website. Tracking of training is maintained via ERI database. Compliance is assured through initial and reminder notification and holding IRB approval notices when necessary. In December 2006, the IRB Administrator (Denise Tritt) completed certification training through the National Association of IRB Managers. PERSONNEL At the end of the fiscal year, the ERI employed 109 employees - a slight decrease from the previous fiscal year of 113 employees. The number of ERI personnel working on projects was 106 and the number employed by administration was three. There were 10 full time employees and 96 part time employees. The average monthly payroll amount processed by the ERI was $89,492, an increase of 4%. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 4 Payroll (Monthly) $100,000 $90,000 $89,492 $80,000 $85,982 $70,000 $70,413 $60,000 $50,000 $72,333 $40,000 $30,000 $20,000 $10,000 $2003-2004 2004-2005 Olive View-UCLA Education & Research Institute 2005-2006 2006-2007 2006 – 2007 Annual Report Page 5 RESEARCH AWARDS Listed below are the following categories of research awards: Federal/State, ERI Seed Grants, Clinical Trials/For-Profit Awards. This does not include approved research that is sponsored by various research funds or has no sponsor. At the close of the fiscal year, there were 86 sponsored projects approved for research in the ERI. This represents an increase of 12% from last year’s total of 77. New Federal & State Awards “Progression and Health Impacts of Parkinson’s Disease Motor and Non-Motor Manifestations (Parkinson’s Disease quality of Life Project” – Funded by UCLA – NIH/NINDS - Charles Flippen, M.D., Neurology “Insulin Resistance Intervention after Stroke Trial (Yale University)” – Funded by Yale University – NIH/NINDS - Bruce Ovbiagele, M.D. Neurology “The Olive View Memory Disorders Program” – Funded by Unihealth Foundation - Jaime Fitten, M.D., Psychiatry and Sheldon Wolf, M.D., Neurology “Evaluating a Clinic-Based Program to Detect and Treat Depression Among Low-Income African American and Latino Patients” – Funded by Robert Wood Johnson Foundation - Lacey Wyatt, M.D., Ambulatory Medicine On-Going Federal & State Awards “Research to Stimulate Assessment of the Potential for the Point-of-Use (POU) and Point-of-Entry (POE) Filters to Promote Growth of Mycobacterium avium Complex (MAC) Organisms in Potable Water” - Funded by the Environmental Protection Agency (EPA) - Timothy Aronson, Department of Pathology “Rapid Identification of Key Pathogens in Wound Infections by Molecular Means” –– Robert Bennion, M.D., Surgery - Funded by Brentwood Biomedical Research Institute/Department of Defense. This project is in its third year. “Pilot Feasibility Study of Trigeminal TENS for Intractable Epilepsy” – Funded by Advanced Biologics – Christopher DeGiorgio, M.D., Neurology “Alzheimer’s Disease Research Center - Presentation of Alzheimer’s and Vascular Dementia in Hispanics and African Americans” - Jaime Fitten, M.D., Neurology - Funded by the State of California/UCLA. This project is in its ninth year. “Clinical Resource Management Disease Management Program – Phase I” – Jeff Guterman, M.D. Funded by California Health Care Foundation. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 6 “Consented High Performance Index/Retrieval Pathology” – Funded by UCLA/NIH - Paul Liu, M.D., Pathology “Early Recognition of Asymptomatic Left Ventricular Dysfunction in Minority Groups” – Funded by UCLA School of Nursing. Aurelia Macabasco-O’Connor, M.D., Nursing. The “National Neurological AIDS Bank” project under the direction of Dr. Glenn Mathisen is in its ninth year of funding. It is funded by the NIH NIAID/UCLA. “Management of Coccidioidomycosis Meningitis in the Post-Fluconazole Era” – Glenn Mathisen, M.D., Med “Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT)” – Funded by New England Research Institute – NIH/NHLBI - Sheba Meymandi, M.D., Medicine/Cardiology “Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers” – Funded by HyperMed NIH/NIDDK – Aksone Nouvong, DPM, Dept. of Surgery. “The Field Administration of Stroke Therapy-Mg Fast MAG” – Funded by UCLA/NIH – Vena Ricketts, M.D., Emer Med “Well-Integrated Screening and Evaluation for Women Across the Nation (WISEWOMAN) In California – Heart of the Family” – Funded by the Centers for Disease Control and the State of California - Satwant Sidhu, M.D., Ambulatory Medicine “The Perinatal Case Management Program” (also known as Project Dream - Developing Resources through Educational Assistance and Management). This project is a perinatal case management program for women who abuse alcohol and/or other drugs and who also are pregnant or have children. Project DREAM provides families with support and referrals and services to outside agencies. Rochelle Tyler, M.D. is the Principal Investigator at Olive ViewUCLA Medical Center. The project is in its 12th and last year at Olive View. “Emergency Department Sentinel Network for Surveillance of Emerging Infections” - Under the direction of David Talan, M.D. and funded by the Centers for Disease Control (CDC). Subcontracts were again issued to ten separate sites throughout the United States. The project is in its 12th budget year at Olive View. “Appendicitis and Protein Markers of Appendicitis” – Funded by ProteinLogic, LTD – Jesse Thompson, M.D., Surgery ERI Seed Grants In September 2006 applications for Seed Grants were announced. The ERI awarded a record Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 7 number of seven seed grants this year, totaling $19,500 with funding beginning January 1, 2007. This year’s recipients are as follows: Jetotsna Grover, M.D., Dept. of OB/Gyn – “Outpatient versus Inpatient Use of Transcervical Foley Catheter for Cervical Ripening – Is There a Difference?” – Amount funded: $2,000. This study will study the effectiveness and safety of mechanical cervical ripening for induction of labor with a transcervical foley catheter. Timothy Jang, M.D., Dept. of Emergency Medicine – “Ultrasonographic, Non-Invasive Assessment of Central Venous Pressure in patients with Suspected Sepsis” – Amount funded: $2,000. The purpose of this study is to assess the accuracy of simple DEM sonography for assessing central venous pressure and intravascular volume status in patients with suspected sepsis. Melinda Maggard, M.D., Dept. of Surgery – “Using Quality Indicators to Improve the Care of Breast Cancer Patients” – Amount funded: $3,500. This study will use quality indicators to measure the quality of care delivered to breast cancer patients. Sheba Meymandi, M.D., Dept. of Medicine (Cardiology) – Incidence of Chagas disease in Immigrant Patients with Conduction Abnormalities on Electrocardiogram” – Amount funded: $2,000. This study proposes to enroll 400 individuals with RBBB, LAFB or LBBB on electrocardiogram to determine the incidence of Chagas disease. Aksone Nouvong, DPM, Dept. of Surgery – “Effects of Orthotics on Pregnancy-Related Changes in Foot Morphology” – Amount funded: $3,500. This study will evaluate 100 patients, 50 randomized to receive customized orthotics and 50 control patients. Three serial scanning foot measurements will be taken first at the onset of pregnancy, again late in the third trimester, and finally 2-6 weeks post partum. The data will allow the investigators to determine if foot size and shape is altered during pregnancy resulting in permanent mechanical changes, and if intervening with orthotics to support the arch through pregnancy can prevent arch collapse with subsequent reduced risk of developing midfoot osteoarthritis. Michael Rotblatt, M.D., Dept. of Medicine – “Hyperlipidemia Survey for Primary Care Providers” – Amount funded: $3,500. This study will administer a survey to primary care providers to determine if they are utilizing NCEP guideline steps and if not, the barriers for omitting these steps. Christopher Tarnay, M.D., Dept. of OB/Gyn – “Sexual Function and Anatomic Outcomes in Anterior Vaginal Reparative Surgery Using Dermal Xenograft; A Comparative Trial” – Amount Funded: $3,000. This study will look at the impact of graft augmentation in pelvic organ prolapse repair as it relates to sexual function and anatomic outcome. In addition to the above, there are 13 ongoing seed grants. Clinical Trials/For Profit Awards Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 8 During the past year, the ERI successfully negotiated six new clinical trials and for-profit awards. They are as follows: Fredrick Abrahamian, D.O., Emergency Medicine – “An Epidemiological Study to Evaluate the Seasonality of Respiratory Syncytial Virus-Associated Lower Respiratory Tract Infections (LRI) or Apnea in Infants in the Emergency Department (MI-MA133)” – Funded by MedImmune, Inc. Arthur Jeng, M.D., Medicine/Infectious Disease – “A Multicenter, Randomized, Double-Blind, Comparison Study of the Safety and Efficacy of a Once-Daily Dose of Tigecycline vs. Ertapenem for the Treatment of Foot Infections in Subject with Diabetes - 3074K5-319-WW” – Funded by Wyeth Research. Sheba Meymandi, M.D., Medicine/Cardiology – “A Double-blind, Randomized, PlaceboControlled, Multicenter Study to Assess the Efficacy and Safety of Darbepoetin alfa Treatment on Mortality and Morbidity in Heart Failure (HF) Subjects with Symptomatic Left Ventricular Systolic Dysfunction and Anemia (#20050222)” – Funded by Amgen. David Talan, M.D., Emergency Medicine – “Randomized, Double-Blind, Multicenter Study of Ceftobiprole Medocaril Versus Ceftriaxone with/without Linezolid in Treatment of Subjects Hospitalized with Community-Acquired Pneumonia” – Funded by Johnson & Johnson. David Talan, M.D., Emergency Medicine – “An Epidemiological Study to Evaluate a Multi-marker INdex for the Diagnosis of Sepsis in the Emergency DepartmenT (MINDSET) - Protocol Number BSTE-0501” – Funded by Biosite. Robin Wachsner, M.D., Medicine/Cardiology – “Lipid Treatment Assessment Project 2 (L-TAP2) NRA 5090005” – Funded by Pfizer, Inc. In addition to the above clinical trials, there are currently four new clinical trials in negotiation or pending final contract approval and 40 open clinical trials. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 9 REVENUE Included in the total revenue source is revenue earned from IRB review. The following chart shows ERI Revenue by funding source for 2006-2007: ERI Revenue by Source $748,326 $800,000 $629,337 $700,000 $600,000 $498,811 $500,000 $400,000 $320,572 $268,852 $300,000 $173,509 $168,725 $200,000 $100,000 $5,948 $Sta te/ Lo No n ca lG ov t Cli n ica l -Pr ofi tF Aw ard s nd Aw ard s Fo Stu die s rP rof Fe it C de ral on tr ac t& Gr an Va rio Re se arc h ts us Aw ard s Re se arc h Pa tie n tS erv i Mi sc .A ce F un ge nc ies ds Payment for services includes funds generated by personal services by investigators, i.e. expert testimony, and outside contracting. At the request of the principal investigator, monies are payable to the ERI and used for the individual investigator’s various research and or education purposes. Total revenue for the year was $2,814,081. Last year’s revenue was $2,849,687. SCIENTIFIC MISCONDUCT In February 2007 the ERI filed its annual report with the Office of Research Integrity/DHHS on possible research misconduct. No allegations were reported during the year. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 10 APPENDICES Board of Trustees - Treasurer’s Report ERI Committee Lists Overhead & Rate Data Sheet Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 11 OLIVE VIEW-UCLA EDUCATION & RESEARCH INSTITUTE BOARD OF TRUSTEES Treasurer’s Report RESEARCH FUNDS 2004-2005 2005-2006 2006-2007 (Revised) (Revised) (Preliminary) Previous Year Unexpended Funds $1,661,659 $1,118,567 $1,414,181 a Current Year Revenue Subtotal Revenue $1,819,308 $3,480,967 $2,502,027 $3,620,594 $2,539,370 b $3,953,551 Current Year Expenses $2,362,400 $2,206,413 $2,113,687 c TOTAL REVENUE LESS EXPENSE $1,118,567 $1,414,181 $1,839,864 Previous Year Unexpended Funds $477,772 $427,153 $416,851 d Current Year Revenue Expenses $317,696 $368,315 $311,764 $322,066 $320,573 e $323,622 f TOTAL REVENUE LESS EXPENSE $427,153 $416,851 $413,802 ADMINISTRATIVE FUNDS a - carry forward from previous year column b - revenue and expense report less admin and interdept transfers c - revenue and expense report less admin and interdept transfers d - carry forward from previous year column e - report for admin f - expense report for admin Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 12 OLIVE VIEW-MEDICAL CENTER EDUCATION AND RESEARCH INSTITUTE RESEARCH & EDUCATION OPERATIONS COMMITTEE 2006 - 2007 Location Extension President: Andrew Wong, M.D., Medicine 2B182 3205 President Elect: Paul Schmit, M.D., Surgery 2B156 3194 Treasurer/Fin.: Paul Liu, MD - Pathology 1A140 4033 Secretary: William Loos, MD, - Medical Admin 2C138 3025 Clinical Operations Committee (Inactive) Jesse Thompson, M.D. - Surgery 2B156 3194 Hospital Azar Kattan - Hospital Admin 2C155 3005 HSPC Anthony Shaw, M.D. - Surgery 2B156 3194 Ex-Officio: Invited Guests*: Fred Abrahamian, M.D., Emer Med North Annex Staff: Lisa E. Gipti, Accountant Denise Tritt, Business Manager ERI ERI 3434 3434 *Receives agenda only. Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 13 OLIVE VIEW-UCLA EDUCATION & RESEARCH INSTITUTE FINANCE COMMITTEE July 1, 2006 - June 30, 2007 Paul Liu, M.D., Chair Pathology 1A140 4534 Andrew Wong, M.D. Medicine 2B182 3205 Paul Schmit, M.D. Surgery 2B156 3194 William Loos, M.D. Medical Administration 2C138 3025 Lisa Gipti, Accountant ERI ERI 3434 Denise Tritt, Bus Mgr ERI ERI 3434 Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 14 OLIVE VIEW-UCLA EDUCATION & RESEARCH INSTITUTE HUMAN SUBJECT PROTECTION COMMITTEE - FWA 00000495 2006-2007 (April 20, 2007) Member Anthony Shaw, M.D. Department Chair Address Extension One South Orange Grove, #9 Pasadena, CA 91105 (626) 796-8588 Vern Campbell, M.Div., Chaplain/Community Mbr 1D142 3080 Arthur Jeng, M.D. Medicine 2B182 3205 Azar Kattan Hospital Administration 2C155 3005 Yvette Kemhadjian, R.N. Medical Administration 2C138 3026 Greg Moran, M.D. Emergency Medicine North Annex 3113 Trudy Olins, R.N. Nursing 2C197 3168 Rita Oregon, M.D. OB/GYN 2B163 3222 Bruce Ovbiagele, M.D. Neurology North Annex 3104 Alan Shewmon, M.D. Neurology 2C136 3104 Jeanne Wallace, M.D. Medicine 2B182 (818) 313-0551 Terry Wolfe, Ph.D. Community Member 1503 Wildwood Drive Los Angeles, CA 90041 (323) 258-4675 Andrew Wong, M.D. Medicine/Rheumatology 2B182 (818) 313-1021 Staff Research Admin Office 3434 1D102 6D129 1C101 4076 3343 3069 3A108 3233 North Annex 3242 2C199 3167 3A108 3180 Staff Denise Tritt, CIM Expert Consultants (As Needed) Gail Hansen, M.D. Radiology Albert-Jan Kettenis, M.D. Psychiatry M. Salahi, M.S., M.B.A./ Pharmacy G. Yamamoto (Consultant but receives entire packet) Maureen Simms Chair, Bioethics Cte. (Consultant but receives entire packet) Alternate Committee Members Christopher DeGiorgio, M.D. Neurology (for Alan Shewmon, M.D.) Marcie Hamilton, R.N. Nursing (for Kathleen Battersby, R.N.) Maureen Simms, M.D. Pediatrics (for C.Ewing) Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 15 Olive View-UCLA Education & Research Institute OVERHEAD & RATE DATA SHEET EFFECTIVE JANUARY 1, 2006 Federal TAX I.D. NO. 95-2249539 OVERHEAD RATES: Sponsored Research: Investigator Generated Protocols* Industry Sponsored Clinical Trials Education/Service Programs 21.0%** Modified Total Direct Cost*** 25.0% Total Direct Cost 20.0% Modified Total Direct Cost Continuing Medical Education (CME) Patient Service Funds Gifts 15.0% 15.0% 5.0% EMPLOYEE FRINGE BENEFITS: (including taxes) Total Direct Cost Total Revenue Revenue 26% for > 75% effort 13% for < 75% effort PER DIEM AND MILEAGE: The ERI uses per diem & mileage rates used by the State of California. The daily per diem rate will be used when itemized expenses are not claimed or receipts are not available. With or without receipts, the maximum per diem, including meals, is $46. Per diem is claimed for trips of 21 hours or more. In- & Out-of State Daily Per Diem Lodging Mileage $46.00 actual cost (for locations > 50 miles from OVMC or home-whichever is closer) 44.5 cents per mile (effective 1/1/06) BUSINESS MEALS: Business meals include recruitment and other situations that promote the research and education activities of the ERI. Business meals applies only to those funds and projects that allow for such expenses. When reimbursement is requested, a statement of the purpose of the meeting with a list of those attending and receipts are required. Alcoholic beverages are not reimbursable. Reimbursement is made to an ERI member or employee. The maximum reimbursable meal expenditure (including tax and 15% tip) for each person is as follows. Charges for facility rental (if applicable) is not included. Breakfast Lunch Dinner $ 10.00 18.00 40.00 * Submitted to e.g., Public Health Service, American Cancer Society ** 22.1% is the rate established with DHHS. The actual rate charged is currently 21%. *** excludes cost of equipment, patient care and annual subcontract costs in excess of $25,000 Olive View-UCLA Education & Research Institute 2006 – 2007 Annual Report Page 16