Introduction to Anatomy and Physiology Lecture An Overview of Anatomy Anatomy - The study of the structure of the human body ana- = apart; -tomy = to cut Subdivisions: Gross vs Microscopic Systemic vs Regional Developmental vs Functional Physiology - The study of body function An Overview of Anatomy Branches of anatomy: Gross (macroscopic) vs Microscopic Gross Anatomy – visible with little or no visual aid Surface anatomy – without dissection and with little, or no, visual aid Microscopic Anatomy – can only be seen through extreme magnification Histology – the study of tissues Cytology – the study of cells Regional vs Systemic Regional Anatomy – anatomical structures in a region The blood and lymphatic vessels of the lower leg Systemic Anatomy – anatomical structures of an organ system Alimentary canal: oral cavity pharynx esophagus stomach duodenum jejunum ileum cecum ascending colon transverse colon descending colon sigmoid colon rectum Hierarchical Organization of Structure Levels of organization of the body: >> Chemical >> Cellular >> Tissue >> Organ >> System >> Organism 1 Chemical Level – atomic & molecular level CHNOPS (or SPONCH) Four most common elements: carbon, hydrogen, oxygen, and nitrogen Six essential elements: carbon, hydrogen, nitrogen, oxygen, phosphorus, sulfur (CHNOPS) plus potassium and calcium = 99% of human body mass Molecules: H2O, carbohydrates, proteins, fats, and nucleic acids All of these molecules are organic (except water because it does not contain carbon) Cellular - Smallest living unit of the body A cell is the basic unit of both structure and function in a living being, smallest unit capable of carrying out the processes associated with life. Examples: Hepatocytes (liver cells) Adipocytes (fat cells) Leukocytes (immune cells) Keratinocytes (skin cells) Chondrocytes (cartilage cells) Erythrocytes (red blood cells) More Examples of Body Cells: 2 Tissue - A group of cells performing a common function A tissue is a group of cells & the materials surrounding them that have a common function or provide a similar service for the body. There are 4 primary tissue types in the human body: epithelial, connective, muscle, and nervous Organ – Two or more tissue types Two or more types of basic tissues organized together to perform a particular function or functions Example: Stomach Inside of stomach lined with epithelial tissue Wall of stomach contains smooth muscle tissue Nervous tissue in stomach controls muscle contraction and gland secretion Connective tissue proper binds all the above tissues together 3 System – Groups of organs Groups of organs that perform related functions and interact to accomplish a common activity essential to survival of the whole body. Sometimes an organ is part of more than one system. There are eleven human body systems. They do not act in isolation from one another Organism – A living entity Various body systems structurally and functionally linked together as an entity separate from the external world. One living individual. Systemic Anatomy - The Integumentary System - Forms external body covering, protects deeper tissues from injury, synthesizes vitamin D, site of cutaneous receptors (pain, pressure, etc.) and sweat and oil glands - The Skeletal System - Protects and supports body organs, provides a framework for muscles, blood cells formed within bones, stores minerals - The Muscular System - Allows manipulation of environment, locomotion, facial expression, maintains posture, produces heat - The Nervous System - Fast-acting control system, responds to internal and external changes - The Endocrine System - Glands secrete hormones that regulate growth, reproduction, and metabolism - The Cardiovascular System - Blood vessels transport blood, carries oxygen and carbon dioxide, also carries nutrients and wastes, heart pumps blood through blood vessels - The Lymphatic System - Picks up fluid leaked from blood vessels, disposes of debris in the lymphatic system, houses white blood cells (lymphocytes), mounts attack against foreign substances in the body 4 - The Respiratory System - Keeps blood supplied with oxygen, removes carbon dioxide, gas exchange occurs through walls of air sacs in the lungs - The Digestive System - Breaks down food into absorbable units, indigestible foodstuffs eliminated as feces - The Urinary System - Eliminates nitrogenous wastes, regulates water, electrolyte, and acid-base balance - Reproductive System - Overall function is to produce offspring, testes produce sperm and male sex hormones, ovaries produce eggs and female sex hormones, mammary glands produce milk Gross Anatomy Anatomical position – a common visual reference point Person stands erect with feet together and eyes forward Palms face anteriorly with the thumbs pointed away from the body Regional Terminology - Regional terms name the specific body areas. o Axial region – the main axis of the body (head, trunk) o Appendicular region – the limbs (arms, legs) - Use the figures and your textbook to define the following regions: o Oral – o Lumbar – o Orbital – o Pubic – o Occipital – o Inguinal – o Cervical – o Gluteal – o Thoracic – o Femoral – o Axillary – o Patellar – o Brachial – o Popliteal – o Antecubital – o Sural – o Antebrachial – o Calcaneal – o Abdominal – o Digital – 5 6 Directional Terminology Orientation and Directional terminology Refers to the body in anatomical position Standardized terms of directions are paired Be able to define: Superior Inferior Anterior Posterior Ventral Dorsal Medial Lateral Proximal Distal Superficial Deep Ipsilateral Contralateral 7 Orientation and Directional Terms 8 Body Planes Coronal (frontal) plane - Lies vertically and divides the body into anterior and posterior parts Sagittal plane – Lies vertically and divides the body into left and right divisions; may or may not be symmetrical Midsagittal (median) plane – A specific sagittal plane that directly on the midline and divides body into symmetrical left and right divisions Parasagittal (non-median) plane – Any sagittal plane other than the midsagittal plane that divides the body into non-symmetrical left and right divisions Transverse (horizontal) plane - runs horizontally and divides body into superior and inferior parts Body Cavities Dorsal body cavity Cranial cavity Brain Vertebral cavity Spinal cord Ventral body cavity Thoracic cavity Two pleural cavities Left pleural cavity Right pleural cavity Mediastinum contains the heart surrounded by the pericardial sac Abdominopelvic cavity Abdominal cavity contains the liver, stomach, kidneys, and other organs Pelvic cavity: contains the bladder, some reproductive organs, and rectum 9 Serous Cavities and Membranes Serous cavities – the slit-like space within a body cavity lined by serous membranes There are three enclosed serous cavities with no openings to the external surface of the body Pericardial cavity surrounds the heart Pleural cavity surrounds the lung Peritoneal cavity surrounds abdominopelvic viscera The serous membrane (serosa) that lines the cavities is either parietal or visceral A parietal serosa covers the wall of the cavity (parietal = wall) A visceral serosa covers the organs within the cavity (visceral = organs) Serous Cavities and Membranes The pericardial cavity surrounds the heart Serous membranes Parietal pericardium Visceral pericardium 10 Serous Cavities and Membranes Pleural cavities surround the lungs Serous membranes Parietal pleura Visceral pleura Peritoneal cavity surrounds abdominopelvic viscera Serous membranes Parietal peritoneum Visceral peritoneum Other Body Cavities Oral cavity – lined with mucous membrane Nasal cavity – lined with mucous membrane Orbital cavities - house the eyeballs Middle ear cavities - house the tiny ear ossicles Synovial cavities – also known as joint cavities 11 Abdominal Regions Abdominal regions divide the abdomen into nine regions Abdominal Quadrants Abdominal quadrants divide the abdomen into four quadrants Right upper and left upper quadrants Right lower and left lower quadrants 12