HEMATOLOGY/ONCOLOGY ROTATION DESCRIPTION ROTATION TITLE: Inpatient Hematology/Oncology SITE DESCRIPTION KKUH 25 B and 34 A are heme/onc unit. Patients are primarily admitted for complications of treatment or disease progression, and small percentages are admitted for inpatient elective chemotherapy. We also provide inpatient end-of-life care as needed. The Oncology service includes patients with solid cancers, primarily lung, breast, esophageal, head & neck, bladder, pancreatic, and lymphomas. The Hematology service includes patients with acute or chronic leukemias, high-grade lymphomas, multiple myeloma, sickle cell disease, ITP, and TTP. Clinical pharmacy services are comprehensive, but focus most on pharmacokinetics, pain/nausea/other symptom management, discharge counseling, and chemotherapy counseling ROTATION PRECEPTOR Lamya Alnaim, PharmD ROTATION OBJECTIVES KNOWLEDGE OF DISEASE STATES In addition to the general core rotation objectives, the student will be able to Describe the symptomatology, physical findings, pathophysiology, diagnostic procedures, laboratory tests, primary and alternative pharmacotherapies, and non-pharmacological treatments for the following medical illnesses according to patients encountered in the rotation: a. b. c. d. e. f. g. h. i. j. k. l. m. Acute lymphocytic leukemia Acute nonlymphocytic leukemia Chronic myelogenous (granulocytic) leukemia Chronic lymphocytic leukemia Malignant lymphomas (Hodgkin's and non-Hodgkin's) Breast cancer Lung cancer Squamous head and neck cancer Gastrointestinal cancers 1) Gastric 2) Pancreatic 3) Hepatocellular 4) Colorectal Prostate/testicular cancer Uterine/ovarian cancer Renal/bladder cancer CNS neoplasms 1 KNOWLEDGE OF OTHER TREATMENT CONSIDERATIONS a. Differentiate the approach to cancer therapy relative to the ultimate goal: 1) Curative 2) Palliative 3) Cytoreductive 4) Adjuvant b. State the rationale for the use of combination chemotherapy in the treatment of neoplastic disease c. Describe the criteria for staging malignancies and the role of tumor markers in the diagnosis and treatment of malignant disease d. Describe the significance and treatment/prevention of the following complications observed in the cancer patient: 1) Infections (bacterial, fungal, viral) 2) Pain 3) Hyperuricemia 4) Nausea and emesis 5) Electrolyte imbalances 6) Stomatitis 7) Nutritional deficiencies ROTATION RESPONSIBILITIES: • Provide comprehensive clinical pharmacy services to patients on the hematology or oncology service. • Provide education to physicians, nurses, and health care providers about appropriate drug therapy. • Design and recommend appropriate dosage regimens for drug therapy based upon pharmacokinetics, therapeutic index, and patient-specific parameters. • Develop and initiate alternative treatment plans should the initial regimen fail to produce the desired effect or prove toxic. • Select and recommend appropriate therapeutic endpoints for attaining safe, effective, and cost efficient pharmacologic outcomes. • Retrieve, evaluate, and apply the medical literature as a means of providing patient-specific drug information to health care providers and patients. • Document your activities in a patient specific record as appropriate for therapeutic drug monitoring, nutrition, pharmacotherapy consults, and discharge counseling. All policies outlined in the Student Rotation Manual provided by the King Saud College of Pharmacy must be followed while on the rotation ACTIVITIES: Refer to the Student Rotation Manual Expected hours • 8 AM to 12 PM As patient care requires, the above listed times may vary. 2 Required meetings •Daily session with preceptor • Weekly session with Group Required readings As assigned by the preceptor. Activities for Oncology Rotation Each day you are expected to 1- Quick review of all patients in the service for drug therapy problem and recommend interventions. -Patients will be divided between the 3 students. -patients are identified by consultant name (Dr. Diab, Dr. Huda OR AbdualKareem, Prof. Momen, and Dr. Amer OR Aleem) 2- Be prepared to discuss these problem and interventions Each students will be required to hand in 2 full case workup in the form provided with continued follow up through out the rotation Each week there will be a reading topic to be discussed from the handouts 3