For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
Curriculum Vitae
Personal information
First name / Surname
Address(es)
INRA Val de Loire – Site 213 37380 NOUZILLY
Telephone
02 47 42 75 67
Mobile
06 37 08 70 69
E-mail
Nationality
Date of birth
Gender
Personal statement and
statement of intent
Education and training
Location and dates
Title of qualification awarded
Principal subjects/occupational skills
covered
Name of Institute
CV_AgSk/AgSk+_v.1
Guillaume Sallé
Guillaume.Salle@tours.inra.fr
French
4 September 1984
Male
After graduating as a veterinarian, I moved into research to investigate the genetic
basis of sheep resistance or susceptibility to parasitic nematodes. During this project I
used knowledge in parasitology and genetics combined with acquired skills in
bioinformatics to identify and investigate the functional properties of one genomic
region. Following this project, I am now involved in two research strands in the “war
against worms”, i.e. the development of integrated strategies for field application in
horses and small ruminants, and the mining of parasitic nematodes genomes to
unravel novel targets.
Over the first two years, I have been mostly dedicated to the first strand of research
for which I have developed a collaborative network for both sheep and horse topics
with prolific outputs (papers and granted projects). Now I would like to get more
involved in the second strand of research, i.e. nematode genome exploration. The
Sanger Institute has proven to be a reference institute in the field with many
reference genomes produced. I would like to ask for an Agreenskill grant for a stay at
the Sanger Institute, in J. Cotton’s lab. During this stay I would analyze some NextGeneration Sequencing data from parasitic nematodes (H. contortus and P. equorum)
while developing and strengthening a collaborative network between our team, the
Sanger Institute and Canadian research teams in McGill university (R. Beech) and
Calgary university (J. Gilleard).
Not only reinforcing my skills in bioinformatics and population genomics, this stay will
help building future projects for the detection of novel therapeutic targets.
Specify information regarding PhD and MSc
TOULOUSE, 2014
None
De novo RNAseq data assembly
Initiation to sequences alignment and phylogeny
INRA GenoToul
First Name – Last name – Date
[1]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
Location and dates
Title of qualification awarded
Principal subjects/occupational skills
covered
Name of Institute
Location and dates
Title of qualification awarded
Principal subjects/occupational skills
covered
TOULOUSE, 2009 – 2012
PhD (under the direction of P. Jacquiet and C. Moreno)
Detection and functional investigation of genomic regions affecting resistance to
parasitic nematodes in sheep
QTL detection analyses with SNP markers (Linkage analysis, GWAS)
Marker-assisted selection
Gene expression study (qPCR)
Parasitology
Institut National Polytechnique de Toulouse
LIEGE (BELGIUM), 2009
Summer Institute in Statistical Genetics
QTL detection methods
Micro-array data analysis
Name of Institute
Liège university
Location and dates
TOULOUSE, 2009
Title of qualification awarded
Principal subjects/occupational skills
covered
Name of Institute
Location and dates
Title of qualification awarded
Principal subjects/occupational skills
covered
Name of Institute
Location and dates
Title of qualification awarded
Principal subjects/occupational skills
covered
Name of Institute
Location and dates
CV_AgSk/AgSk+_v.1
Msc training
QTL detection for resistance to S. abortusovis in sheep
6-month training
under the direction of C. Moreno
Linkage analysis (microsatellite markers)
INRA
PARIS, 2008-2009
Msc in Animal Genetics and Breeding
Quantitative genetics, Population genetics, Genome structure
Agroparistech
EDINBURGH (UK)
2007
DVM Training
Genetic parameter estimation for resistance to parasitic nematodes in sheep
under the direction of S. Bishop
3-month training
EU Leonardo funded project
The Roslin Institute
TOULOUSE, 2004-2009 (MUNICH, 2007-2008)
First Name – Last name – Date
[2]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
Title of qualification awarded
Principal subjects/occupational skills
covered
Name of Institute
CV_AgSk/AgSk+_v.1
Doctor in Veterinary Medicine
Veterinary sciences
Ecole Nationale Vétérinaire de Toulouse
(Ludwig-Maximilians Universität München, 2007-2008)
First Name – Last name – Date
[3]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
Work experience
Location and dates
Occupation or position held
Main activities and responsibilities
Nouzilly FRANCE
2012 – to date
Research Engineer
Mining nematode genomes for novel therapeutic options
genetic architecture of ivermectin resistance in P. equorum)
Research on integrated management of gastro-intestinal nematodes in sheep and
horses
Dissecting the anthelmintic potential of nicotinic-derivative
containing plants
Development of innovative biomarkers of nematode infection
Mining the sheep genome for resistance genes to nematodes
Management of a parasitic nematode biological databank
Name of employer
INRA Animal Health division
Location and dates
Toulouse, FRANCE
2009 – 2012
Occupation or position held
Main activities and responsibilities
Name of employer
CV_AgSk/AgSk+_v.1
PhD candidate
Detection and functional investigation of genomic regions affecting resistance to
parasitic nematodes in sheep
QTL detection analyses with SNP markers (Linkage analysis, GWAS)
Marker-assisted selection
Gene expression study (qPCR)
Parasitology
INRA / Ecole Nationale Vétérinaire de Toulouse
First Name – Last name – Date
[4]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
Languages
Mother tongue(s)
Other language(s)
FRENCH
Understanding
Speaking
Writing
Listening
Reading
Spoken interaction
Spoken production
ENGLISH
C1
C1
C1
C1
C1
GERMAN
B2
B1
B2
B1
B1
European level (*)
Add more languages if relevant
(*) Common European Framework of Reference for Languages
http://europass.cedefop.europa.eu/en/resources/european-language-levels-cefr
Academic Record
Add as many lines as needed, delete fields which are not relevant to your profile
Publications
Accepted, in press and published articles / papers:
 The list of your publications must be
numbered, in chronological order with the
most recent first.
 Publication details must be according to
standard systems of referencing e.g. Authors
(x, y, z...), year, title, journal, issue
n°/volume/page range).
 Please specify all contributing authors,
highlighting your name in bold and respecting
the authors’ order.
 Provide any other essential details that will
help reviewers fully assess your contribution to
the publication.
CV_AgSk/AgSk+_v.1
PAPERS
 C.Chylinski, J. Cortet, G. Sallé, P. Jacquiet, J. Cabaret, 2014. Storage of gastrointestinal
nematode infective larvae for species preservation and experimental infections.
Parasitol. Res., accepted.
 Hazard D, Moreno C, Foulquié D, Delval E, François D, Bouix J, Sallé G, Boissy A.,
2014. Identification of QTLs for behavioral reactivity to social separation and humans in
sheep using the OvineSNP50 BeadChip. BMC Genomics. 9;15:778. doi: 10.1186/14712164-15-778.
 Sallé G., Moreno C.R., Boitard, S., Ruesche, J., Tircazes-Sécula, A., Bouvier, F., Aletru,
M., Weisbecker, J-L, Prévot, F., Bergeaud, J-P, Trumel, C., Grisez, C., Liénard, E.,
Jacquiet, P., 2014. Functional investigation of a QTL affecting resistance to Haemonchus
contortus in sheep. Vet. Res., 17;45:68. doi: 10.1186/1297-9716-45-68.
 Assenza F, Elsen JM, Legarra A, Carré C, Sallé G, Robert-Granié C, Moreno CR., 2014.
Genetic parameters for growth and faecal worm egg count following Haemonchus
contortus experimental infestations using pedigree and molecular information. Genet Sel
Evol. 14;46:13. doi: 10.1186/1297-9686-46-13.
 Riggio V, Pong-Wong R, Sallé G, Usai MG, Casu S, Moreno CR, Matika O, Bishop SC.,
2014. A joint analysis to identify loci underlying variation in nematode resistance in three
European sheep populations. J Anim Breed Genet. 8. doi: 10.1111/jbg.12071.
 Baloche G, Legarra A, Sallé G, Larroque H, Astruc JM, Robert-Granié C, Barillet F.,2014.
Assessment of accuracy of genomic prediction for French Lacaune dairy sheep. J Dairy
Sci ;97(2):1107-16. doi: 10.3168/jds.2013-7135
 G. Sallé, P. Jacquiet, L. Gruner, J. Cortet, C. Sauvé, F. Prévot, C. Grisez, J. P. Bergeaud,
L. Schibler, A. Tircazes, D. Francois, C. Pery, F. Bouvier, J. C. Thouly, J. C. Brunel, A.
Legarra, J. M. Elsen, J. Bouix, R. Ruppand C. R. Moreno. 2012. A genome scan for QTL
affecting resistance to Haemonchus contortus in sheep. J Anim Sci., 90(13):4690-705.
doi: 10.2527/jas.2012-5121
 I. Lantier, C.R. Moreno, P. Berthon, G. Sallé, F. Pitel, L. Schibler, A.V. GautierBouchardon, R. Boivin, J.L. Weisbecker, D. François, J. Bouix, E.P. Cribiu, J.M.Elsen, F.
Lantier. Quantitative trait loci for resistance to infection in sheep using a live Salmonella
abortusovisvaccine. Animal genet. 2012 Oct;43(5):632-5. doi: 10.1111/j.13652052.2011.02291.x
CONGRESS ARTICLES
 G. Sallé, J. Cortet, F. Reigner, J. Cabaret, J. Pavie. Etude des coûts de maitrise des
endoparasites équins : enquête terrain et résultats d’expérience. Accepted for 41ème
journée de la recherche équine, Paris, 2015.
 C R Moreno, P Jacquiet, F Bouvier, J Cortet, A Blanchard-Letort, F Guégnard, D
Francois, Y Bourdillon, C Grisez, F Prevot, A Averadère, J Demars, J Sarry, A Stella, F
Woloszyn, K Canale-Tabet, J Cabaret, G Tosser-Klopp and G Sallé.Validation of QTL
affecting resistance to nematodes in sheep identified in a back-cross design in a pure
First Name – Last name – Date
[5]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
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breed population. World Congress of Genetics Applied to Livestock Production,
Vancouver, 2014
R. Rupp, I. Palhière, C. Maroteau, G. Balloche, G. Sallé , A. Tircazes, C. Moreno, G.
Foucras and G. Tosser-Klopp. Mapping QTL Controlling Milk Somatic Cell Counts in
Sheep and Goat Support the Polygenic Architecture of Mastitis Resistance. World
Congress of Genetics Applied to Livestock Production, Vancouver, 2014
S. Kornas, J. Cabaret, M. Skalska, Nowosad B., Wimel L., A. Ricard, G. Sallé. Etude
de la variabilité génétique de la sensibilité aux nématodes dans une population de pursang arabes Polonais et comparaison raciale en France. Accepté pour les 40e Journée
de la Recherche Equine, Paris, 2014
G. Sallé, M. Neveux, J. Cabaret. Enquête sur la gestion du parasitisme par les
vétérinaires équins en France. Accepté pour les 40e Journée de la Recherche Equine,
Paris, 2014
Riggio V., Pong-Wong R., Sallé G., Usai M.G., Casu S., Moreno C.R., Bishop, S.C.
Loci underlying genetic variation in nematode resistance in three sheep populations: a
joint analysis. 64th annual meeting of the European Association for Animal Production.
Nantes 2013
Sallé G., Moreno C.R., Boitard, S., Ruesche, J., Tircazes-Sécula, A., Bouvier, F.,
Aletru, M., Weisbecker, J-L, Prévot, F., Bergeaud, J-P, Trumel, C., Grisez, C., Liénard,
E., Jacquiet, P. Functional investigation of a QTL affecting resistance to Haemonchus
contortus in sheep. 64th annual meeting of the European Association for Animal
Production. Nantes 2013
Hazard D., Foulquié D., Delval E, François D., Sallé G., Moreno C, Boissy A.
Identification of QTL for behavioural reactivity in sheep using the ovineSNP50
beadchip. 63th annual meeting of the European Association for Animal Production.
Bratislava 2012.
G.Sallé, P.Jacquiet, L. Gruner, J. Cortet, C. Sauvé, F. Prévot, F. Bouvier, D.François,
C.Pery, J.Bouix, A.Legarra, R.Rupp and C.R.Moreno. Genomic Mapping of Resistance
to Haemonchus contortusUsing the High-density OvineSNP50 Beachchip. 23th
conference of theWorld Association for Advances in Veterinary Parasitology, Buenos
Aires, 2011.
G. Baloche, H. Larroque, J.M. Astruc, J.M. Babilliot, M.Y. Boscher, P. Boulenc, C.
Chantry-Darmon, C. De Boissieu, G. Frégeat, B. Giral-Viala, P. Guibert, G. Lagriffoul,
C. Moreno, P. Panis, C. Robert-Granié, G. Sallé, A. Legarra, F. Barillet. Work in
progress on genomic evaluation using GBLUP in French Lacaune dairy sheep
breed.62th annual meeting of the European Association for Animal Production.
Stavanger 2011.
R. Rupp, G. Sallé, F. Barillet, H. Larroque, C.R. Moreno. Genome-wide association
study of somatic cell counts in a grand-daughter design of French Lacaune AI rams.
62th annual meeting of the European Association for Animal Production. Stavanger
2011.
C.M.D. Bonnefont, G. Foucras , G. Sallé, S. Teyssèdre, C. Allain, MR. Aurel, D.
Bergonier, C.R. Moreno, R. Rupp. A case control study on genome-wide SNP-based
association mapping of mastitis in Lacaune sheep using the Illumina ovine SNP50
BeadChip. 62th annual meeting of the European Association for Animal Production.
Stavanger 2011.
G.Sallé, P.Jacquiet, L. Gruner, J. Cortet, C. Sauvé, F. Prévot, F. Bouvier, D.François,
C.Pery, J.Bouix, A.Legarra, R.Rupp and C.R.Moreno. QTL detection for resistance to
Haemonchuscontortus in sheep: preliminary study using the OvineSNP50 beadchip.
World Congress of Genetics Applied to Livestock Productio., Leipzig, 2010.
OTHER ARTICLES
Sallé G, Moreno C.R. Apports de la génomique en élevage de petits ruminants. Le nouveau
praticien vétérinaire. Vol 4, n° 17. 2011
Submitted publications:
C.Chylinski, J. Cortet, G. Sallé, P. Jacquiet, J. Cabaret, 2014. Storage of gastrointestinal
CV_AgSk/AgSk+_v.1
First Name – Last name – Date
[6]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
nematode infective larvae for species preservation and experimental infections. Parasitol.
Res., accepted.
S. Kornas*, G. Sallé*, M. Skalska, I. David, A. Ricard, J. Cabaret. Estimation of genetic
parameters for the resistance to gastro-intestinal nematodes in thoroughbred Arabian
horses. Int. J. Para, 2nd revision. (*, both authors equally contributed to the manuscript)
Participation in open calls for proposals as
contributor or leader
-
CORE Organic grant call 2014 (ECOGRASS project, contributor)
Institut Carnot Santé Animale 2014 (GEMANEMA project, leader)
Marie-Curie 2014 (QuantMolPara project, contributor)
Institut Français du Cheval et de l’Equitation 2013 (VERMISEL project, leader)
French Région Centre 2013 (LUPINEMA project, leader)
Institut Carnot Santé Animale 2013 (PARASTRESS project, contributor)
Appel à projets France génomique 2013 (PARCYGEN project, leader)
ANIHWA grant call 2012 (happysheep&goat,contributor)
Graduate teaching as lecturer or training
coordinator
Training coordinator of Msc students :
- M. Michaud (M1 student, Université de Tours): in vitro assay for
anthelmintic resistance detection in cyasthotomins (2013)
- H. Février (M1 student, Université Rennes 1): in vitro study of lupine
seed extracts on nematodes (2013)
Awards and prizes, if any
C. Evrard (Ecole Nationale Vétérinaire Maisons-Alfort): sociological
approach of the anthelmintic use in French trotters breeders (2012)
Léopold Escande prize for PhD work, Toulouse University (2013)
Collaboration and Networking
Participation in collaborative projects
funded by competitive programmes
(specify if at leading position)
Leader of :
 LUPINEMA project (French Région Centre, 2012-2015): anthelmintic properties of
the lupinus spp. plant
 GEMANEMA project (Institut Carnot Santé Animale 2015-2018) : validation of a set
of SNPs for breeding nematode resistant sheep
 VERMISEL project (Institut Français du Cheval et de l’Equitation, 2014-2015) :
Targeted selective treatment in horses
Involved in :
 BIOVIPAR project (French Région Centre, 2012-2015) : sheep-nematode interaction
 EQUIPAR project (Institut Carnot Santé Animale & Institut Français du cheval et de
l’équitation 2012-2015) : Integrated management of parasitic nematodes in horses
Graduate teaching as lecturer or training
coordinator; PhD supervision
Took part to C. Collas’ thesis committee (2013) in collaboration with G. Fleurance
and B. Dumont (INRA UMRH, Clermont)
Training coordinator of Msc students :
-
Membership of professional bodies and
committees
S. Marschesseau (M2 student, Université Rennes 1) : behavioral
assessment of parasitic infection in horses ; in collaboration with
M. Hausberger (CNRS, Université Rennes 1)
Member of the Val de Loire ethics committee (from 2013 to date)
Research management, Technology transfer, and Communication
Other experience and skills relevant
to the application
CV_AgSk/AgSk+_v.1
First Name – Last name – Date
[7]
For administrative use only
APPLICATION ID:
RESEARCHER: Young / Independent
PROGRAMME: AgSk / AgSk+
Scientific References Add up to 3 references
Full name
Carole Moreno-Romieu
Position
Scientist, head of the small ruminants genetics and genomics team
Institution
INRA
Email address
Carole.Moreno@toulouse.inra.fr
Full name
Philippe Jacquiet
Position
Professor in veterinary parasitology
Institution
Ecole Nationale Vétérinaire de Toulouse
Email address
p.jacquiet@envt.fr
Full name
Stephen Bishop
Position
Professor, Group Leader and Chair of Animal Disease Genetics.
Institution
The Roslin Institute and R(D)SVS, University of Edinburgh
Email address
stephen.bishop@roslin.ed.ac.uk
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Heard from collaborators
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[8]