CURRICULUM VITAE
January 1, 2013
Name:
Duncan Charles Krause
Spouse:
Children:
Robin Reeves Krause
Kristen K. McMillan (06/01/82) (married)
Robert W. Krause (08/27/84) (married)
Birth date:
June 1, 1956
Mobile, Alabama
Present Address:
Department of Microbiology
019 Riverbend South Research Bldg.
University of Georgia
Athens, GA 30602
Phone: (706) 542-2671
FAX: (706) 542-3804
E-mail: dkrause@uga.edu
Academic Title:
Professor and Director, Faculty of Infectious Diseases
Department of Microbiology
Education:
1973-1975
1975-1978
1978-1982
Professional Experience:
2007-present
2000-2006
1996-present
1991-1996
1990-1993
1985-1991
1983-1985
1981-1982
1978-1980
La Grange College, La Grange, Georgia; Major: Biology
Auburn University, Auburn, Alabama
B. S. (summa cum laude) Microbiology; March 1978
University of North Carolina, Chapel Hill, North Carolina
Ph.D. Microbiology; December 1982; Major Professor: Joel B. Baseman
“Molecular Analysis of Mycoplasma pneumoniae Cytadsorption”
Director, Faculty of Infectious Diseases
Head, Department of Microbiology, University of Georgia
Professor, Department of Microbiology, University of Georgia
Associate Professor, Dept. of Microbiology, University of Georgia
Graduate Coordinator, Dept. of Microbiology, University of Georgia
Assistant Professor, Dept. of Microbiology, University of Georgia
Post-Doctoral Scientist, Dept. Microbiol. / Immunol., Univ. South
Alabama College of Medicine; with David Wood & Herbert Winkler
Research Assistant, Department of Microbiology, University of Texas
Health Science Center at San Antonio
Research Assistant, Department of Bacteriology and Immunology,
University of North Carolina at Chapel Hill
Publications:
*
Peer-reviewed
*
1. Krause, D. C., D. K. Leith, R. M. Wilson and J. B. Baseman. 1982. Identification of Mycoplasma
pneumoniae proteins associated with hemadsorption and virulence. Infect. Immun. 35:809-817.
PMID: 6802761
*
2. Krause, D. C. and J. B. Baseman. 1982. Mycoplasma pneumoniae proteins that selectively bind to
host cells. Infect. Immun. 37:382-386. PMID: 6809635
*
3. Baseman, J. B., R. M. Cole, D. C. Krause and D. K. Leith. 1982. Molecular basis for cytadsorption
of Mycoplasma pneumoniae. J. Bacteriol. 151:1514-1522. PMID: 6809731
*
4. Leith, D. K., E. J. Hansen, R. M. Wilson, D. C. Krause and J. B. Baseman. 1983. Hemadsorption
and virulence are separable properties of Mycoplasma pneumoniae. Infect. Immun. 39:844-850.
PMID: 6403462
*
5. Krause, D. C., D. K. Leith and J. B. Baseman. 1983. Reacquisition of specific proteins confers
virulence in Mycoplasma pneumoniae. Infect. Immun. 39:830-836. PMID: 6403461
*
6. Krause, D. C. and J. B. Baseman. 1983. Inhibition of Mycoplasma pneumoniae hemadsorption and
adherence to respiratory epithelium by antibodies to a membrane protein. Infect. Immun. 39:11801186. PMID: 6404820
7. Wood, D. O., R. S. Sikorski, W. H. Atkinson, D. C. Krause and H. H. Winkler. 1984. Cloning
Rickettsia prowazekii genes in Escherichia coli K12. In Microbiology 1984, D. Schlessinger, ed. pp.
301-304.
*
8. Krause, D. C., H. H. Winkler and D. O. Wood. 1985. Cosmid cloning Rickettsia prowazekii
antigens in Escherichia coli K12. Infect. Immun. 47:157-165. PMID: 2981194
*
9. Krause, D. C., H. H. Winkler and D. O. Wood. 1985. Cloning and expression of the Rickettsia
prowazekii ADP/ATP translocator in Escherichia coli. Proc. Natl. Acad. Sci. USA, 82:3015-3019.
PMID: 2986146
*
10. Wood, D. O., L. R. Williamson, H. H. Winkler, and D. C. Krause. 1987. Nucleotide sequence
analysis of the Rickettsia prowazekii citrate synthase gene. J. Bacteriol. 169:3564-3572. PMID:
3112124
*
11. Chen, Y.-Y. and D. C. Krause. 1988. Parasitism of hamster trachea epithelial cells by Mycoplasma
pneumoniae. Infect. Immun. 56:570-576. PMID: 2449398
*
12. Krause, D. C. and Y.-Y. Chen. 1988. Interaction of Mycoplasma pneumoniae with HeLa cells.
Infect. Immun. 56:2054-2059. PMID: 2456270
*
13. Williamson, L. R., G. V. Plano, H. H. Winkler, D. C. Krause and D. O. Wood. 1989. Nucleotide
sequence of the Rickettsia prowazekii ATP/ADP translocase-encoding gene. Gene 80:269-278.
PMID: 2555259
14. Krause, D. C. and Y.-Y. Chen. 1990. Oxidative stress response and Mycoplasma pneumoniae
toxicity for tracheal epithelium. In: Recent Advances in Mycoplasmology. Zbl. Bakteriol.
Mikrobiol. Hyg. Suppl. 20. G. Stanok, G. H. Cassell, J. G. Tully and R. F. Whitcomb, eds. Gustav
Fischer Verlag, New York, pp. 705-708.
15. Krause, D. C. 1990. Opal suppression and the expression of Mycoplasma pneumoniae genes in
Escherichia coli. In: Recent Advances in Mycoplasmology. Zbl. Bakteriol. Mikrobiol. Hyg. Suppl.
20. G. Stanok, G. H. Cassell, J. G. Tully and R. F. Whitcomb, eds. Gustav Fischer Verlag, New
York, pp. 204-209.
*
16. Krause, D. C., S. H. Kleven, and K. K. Lee. 1990. Cloning and expression in Escherichia coli of
Mycoplasma gallisepticum antigens recognized during infection in chickens. Avian Dis. 43:466-472.
PMID: 2142422
*
17. Stevens, M. K. and D. C. Krause. 1990. Disulfide-linked protein associated with Mycoplasma
pneumoniae cytadherence. Infect. Immun. 58:3430-3433. PMID: 2119345
*
18. Krause, D. C. and C. B. Mawn. 1990. Physical analysis and mapping of the Mycoplasma
pneumoniae chromosome. J. Bacteriol. 172:4790-4797. PMID: 2118502
*
19. Ogle, K. E. and D. C. Krause. 1991. Cloning and analysis of the gene encoding the cytadherence
phase-variable protein HMW3 from Mycoplasma pneumoniae. Gene 97:69-75. PMID: 1899847
*
20. Stevens, M. K. and D. C. Krause. 1991. Localization of the Mycoplasma pneumoniae
cytadherence-accessory proteins HMW1/4 in the cytoskeleton-like triton shell. J. Bacteriol.
173:1041-1050. PMID: 1899414
2
*
21. Krause, D. C. and K. K. Lee. 1991. Juxtaposition of the genes encoding Mycoplasma pneumoniae
cytadherence-accessory proteins HMW1 and HMW3. Gene. 107:83-89. PMID: 1743522
*
22. Ogle, K. F. and D. C. Krause. 1991. Peptide mapping/western immunoblot procedure for
identification of a truncated mycoplasma protein expressed in Escherichia coli. J. Microbiol.
Methods. 14:143-149.
*
23. Stevens, M. K. and D. C. Krause. 1992. Mycoplasma pneumoniae cytadherence phase-variable
protein HMW3 is a component of the attachment organelle. J. Bacteriol. 174:4265-4274. PMID:
1624421
*
24. Ogle, K. F., K. K. Lee and D. C. Krause. 1992. Nucleotide sequence analysis reveals novel features
of the phase-variable cytadherence accessory protein HMW3 of Mycoplasma pneumoniae. Infect.
Immun. 60:1633-1641. PMID: 1548085
*
25. Hedreyda, C. T., K. K. Lee and D. C. Krause. 1993. Transformation of Mycoplasma pneumoniae
with Tn4001 by electroporation. Plasmid 30:170-175. PMID: 8234492
*
26. Dirksen, L. B., K. Krebes and D. C. Krause. 1994. Phosphorylation of cytadherence-accessory
proteins in Mycoplasma pneumoniae. J. Bacteriol. 176:7499-7505. PMID: 8002573
*
27. Norman, A. F., R. Regnery, P. Jameson, C. Greene and D. C. Krause. 1995. Differentiation of
Bartonella isolates at the species level by PCR-restriction fragment length polymorphism in the
citrate synthase gene. J. Clin. Microbiol. 33:1797-1803. PMID: 7545181
*
28. Hedreyda, C. T. and D. C. Krause. 1995. Identification of a possible cytadherence regulatory locus
in Mycoplasma pneumoniae. Infect. Immun. 63:3479-3483. PMID: 7642280
*
29. Krebes, K. A., L. B. Dirksen and D. C. Krause. 1995. Phosphorylation of Mycoplasma pneumoniae
cytadherence-accessory proteins in cell extracts. J. Bacteriol. 177:4571-4574. PMID: 7635846
*
30. Hahn, T.-W., K. A. Krebes and D. C. Krause. 1996. Expression in Mycoplasma pneumoniae of the
recombinant gene encoding the cytadherence-associated protein HMW1 and identification of HMW4
as a product. Molec. Microbiol. 19:1085-1093. PMID: 8830265
*
31. Dirksen, L. B., T. Proft, H. Hilbert, H. Plagens, R. Herrmann and D. C. Krause. 1996. Sequence
analysis and characterization of the hmw gene cluster of Mycoplasma pneumoniae. Gene. 171:19-25.
PMID: 8675025
*
32. Krause, D. C. 1996. Mycoplasma pneumoniae cytadherence: unraveling the tie that binds. Molec.
Microbiol. 20:247-253. PMID: 8733224
*
33. Krause, D. C., T. Proft, C. T. Hedreyda, H. Hilbert, H. Plagens and R. Herrmann. 1997. Transposon
mutagenesis reinforces the correlation between Mycoplasma pneumoniae cytoskeletal protein HMW2
and cytadherence. J. Bacteriol. 179:2668-2677. PMID: 9098066
*
34. Popham, P., T. -W. Hahn, K. Krebes and D. C. Krause. 1997. Loss of HMW1 and HMW3 in
noncytadhering mutants of Mycoplasma pneumoniae occurs post-translationally. Proc. Natl. Acad.
Sci. USA 94:13979-13984. PMID: 9391138
*
35. Hahn, T.-W., M.J. Willby and D.C. Krause. 1998. HMW1 is required for cytadhesin P1 trafficking
to the attachment organelle in Mycoplasma pneumoniae. J. Bacteriol. 180:1270-1276. PMID:
9495768
*
36. Krause, D.C. 1998. Mycoplasma pneumoniae cytadherence: organization and assembly of the
attachment organelle. Trends in Microbiol. 6:15-18. PMID: 9481818
*
37. Mehock, J,R., C.E. Greene, F.C. Gherardini, T.-W. Hahn, and D.C. Krause. 1998. Bartonella
henselae invasion of feline erythrocytes in vitro. Infect. Immun.66:3462-3466. PMID: 9632625
*
38. Romero-Arroyo, C.E., J.Jordan, S.J. Peacock, M.J. Willby, M.A. Farmer, and D. C. Krause. 1999.
Mycoplasma pneumoniae protein P30 is required for cytadherence and associated with proper cell
development. J. Bacteriol.181:1079-1087. PMID:9973332
*
39. Hahn, T.-W., E.A. Mothershed, R.H. Waldo, III, and D.C. Krause. 1999. Construction and analysis
of a modified Tn4001 conferring chloramphenicol resistance in Mycoplasma pneumoniae. Plasmid.
41: 120-124. PMID: 10087215
3
*
40. Fisseha, M., H.W.H. Göhlmann, R. Herrmann, and D.C. Krause. 1999. Identification and
complementation of frameshift mutations associated with loss of cytadherence in Mycoplasma
pneumoniae. J. Bacteriol. 181: 4404-4410. PMID: 10400600
*
41. Waldo, R.H., P.L. Popham, C.E. Romero-Arroyo, E.A. Mothershed, K.K.. Lee, and D.C. Krause.
1999. Transcriptional analysis of the hmw gene cluster of Mycoplasma pneumoniae. J. Bacteriol.
181: 4978-4985. PMID: 10438770
*
42. Krause, D.C. and M.F. Balish. 2001. Structure, function and assembly of the terminal organelle of
Mycoplasma pneumoniae. FEMS Microbiol. Lett. 198: 1-7. PMID: 11325545
*
43. Balish, M.F., T.-W. Hahn, P.L. Popham, and D.C. Krause. 2001. Stability of M. pneumoniae
cytadherence-accessory protein HMW1 correlates with its association with the triton shell. J.
Bacteriol. 183: 3680-3688. PMID: 11371532
*
44. Jordan, J.L., K.M. Berry, M.F. Balish, and D.C. Krause. 2001. Stability and subcellular localization
of cytadherence-associated protein P65 in Mycoplasma pneumoniae. J. Bacteriol. 183: 7387-7391.
PMID: 11717298
*
45. Willby, M.J. and D.C. Krause. 2002. Characterization of a Mycoplasma pneumoniae hmw3 mutant:
implications for attachment organelle assembly. J. Bacteriol. 184:3061-3068. PMID: 12003948
*
46. Balish, M.F., R.A. Santurri, A.M. Ricci, K.K. Lee, and D.C. Krause. 2003. Localization of
Mycoplasma pneumoniae cytadherence-associated protein HMW2 by fusion with green fluorescent
protein: Implications for attachment organelle structure. Molec. Microbiol. 47:49-60. PMID:
12492853
*
47. Balish,M.F., S.M. Ross, M. Fisseha, and D.C. Krause. 2003. Deletion analysis identifies key
functional domains of the cytadherence-associated protein HMW2 of Mycoplasma pneumoniae. Mol.
Microbiol. 50: 1507-1516. PMID: 14651634
*
48. Chenoweth, M.R., G.A. Somerville, D.C. Krause, K.L. O’Reilly, and F.C. Gherardini. 2004.
Growth characteristics of Bartonella henselae in a novel liquid medium: primary isolation, growthphase dependent phage induction, and metabolic studies. Appl. Environ. Microbiol. 70:656-663.
PMID: 14766538
*
49. Krause, D.C. and M.F. Balish. 2004. Cellular engineering in a minimal microbe: structure and
assembly of the terminal organelle of Mycoplasma pneumoniae. Mol. Microbiol. 51:917-24. PMID:
14763969
*
50. Chenoweth, M.R., C.E. Greene, D.C. Krause, and F.C. Gherardini. 2004. Predominant outer
membrane antigens of Bartonella henselae. Infect. Immun. 72:3097-3105. PMID: 15155610
*
51. Willby, M.J., M.F. Balish, S.M. Ross, K.K. Lee, J.L. Jordan, and D.C. Krause. 2004. HMW1 is
Required for Stability and Localization of HMW2 to the Attachment Organelle of Mycoplasma
pneumoniae J. Bacteriol. 186:8221-8228. PMID: 15576770
*
52. Waldo, R.H. III, J.L. Jordan, and D.C. Krause. 2005. Identification and complementation of a
mutation associated with loss of Mycoplasma pneumoniae virulence-specific proteins B and C. J.
Bacteriol. 187:747-751. PMID:15629945
*
53. Hasselbring, B.M., J.L. Jordan, and D.C. Krause. 2005. Mutant analysis reveals specific
requirement for protein P30 in Mycoplasma pneumoniae gliding motility. J. Bacteriol. 187:62816289. PMID: 16159760
*
54. Waldo, R.H. III and D.C. Krause. 2006. Synthesis, stability, and function of cytadhesin P1 and
accessory protein B/C complex of Mycoplasma pneumoniae. J. Bacteriol. 188: 569-575. PMID:
16385047
*
55. Hasselbring, B.M., C.A. Page, E. S. Sheppard, and D.C. Krause. 2006. Transposon mutagenesis
identifies genes associated with Mycoplasma pneumoniae gliding motility. J. Bacteriol. 188: 63356345. PMID:16923901
56. Balish, M.F. and D.C. Krause. 2006. Mycoplasmas: a distinct cytoskeleton for wall-less bacteria J.
Mol. Microbiol. Biotechnol. 11:244-255. PMID: 16983199
*
57. Hasselbring, B.M., J.L. Jordan, R.W. Krause, and D.C. Krause. 2006. Terminal organelle
4
development in the cell wall-less bacterium Mycoplasma pneumoniae. Proc. Natl. Acad. Sci. USA.
103: 16478-16483. PMID: 17062751
*
58. Krunkosky, T.M., J.L. Jordan, E. Chambers, and D.C. Krause. 2007. Air-liquid interface culture
system: a model to study interactions of Mycoplasma pneumoniae and differentiated human airway
epithelial cells. Microbial Pathog. 42:98-103. PMID: 17261358
*
59. Jordan, J.L., H-Y. Chang, M.F. Balish, L.S. Holt, S.R. Bose, B.M. Hasselbring, R.H. Waldo III, T.M.
Krunkosky, and D.C. Krause. 2007. Protein P200 is dispensable for Mycoplasma pneumoniae
hemadsorption but not gliding motility or colonization of differentiated bronchial epithelium. Infect.
Immun. 75:518-522. PMID: 17043103
*
60. Hasselbring, B.M., C.A. Page, E. S. Sheppard, and D.C. Krause. 2007. Transposon mutagenesis
identifies genes associated with Mycoplasma pneumoniae gliding motility. J. Bacteriol. 189:1179.
Erratum for ref. 56.
*
61. Hasselbring, B.M. and D.C. Krause. 2007. Cytoskeletal protein P41 is required to anchor the terminal
organelle of the wall-less prokaryote Mycoplasma pneumoniae. Mol. Microbiol. 63: 44-53. PMID:
17163973
This work was the cover story and a featured article for invited commentary by another
scientist in the field.
*
62. Hasselbring, B.M. and D.C. Krause. 2007. Proteins P24 and P41 Function in the Regulation of
Terminal Organelle Development and Gliding Motility in Mycoplasma pneumoniae. J. Bacteriol.
189:7442-7449. PMID: 17693502
*
63. Kraft, M., K.B. Adler, J.L. Ingram, A.L. Crews, T.P. Atkinson, C.B. Cairns, D.C. Krause, and H.W.
Chu. 2008. Mycoplasma pneumoniae increases MUC5AC in airway epithelial cells preferentially in
asthma. Eur. Resp. J. 31:43-46. PMID: 18166592
*
64. Driskell, J.D., S. Shanmukh, Y.-J. Liu, S. Hennigan, L. Jones, Y.-P. Zhao, R.A. Dluhy, D.C. Krause,
and R.A. Tripp. 2008. Infectious agent detection with SERS-active silver nanorod arrays prepared by
oblique angle deposition. IEEE Sensors J.8:863-870.
*
65. Cloward, J.M. and D.C. Krause. 2009. Mycoplasma pneumoniae J-domain protein required for
terminal organelle function. Molec. Microbiol. 71: 1296-1307. PMID: 19183275
*
66. Bose, S.R., M.F. Balish, and D.C. Krause. 2009. Mycoplasma pneumoniae cytoskeletal protein
HMW2 and the architecture of the terminal organelle. J. Bacteriol. 191:6741-6748. PMID: 19717588
*
67. Hennigan, S.L., J.D. Driskell, R.A. Dluhy, Y. Zhao, R.A. Tripp, K.B. Waites, and D.C. Krause. 2010.
Detection of Mycoplasma pneumoniae in simulated and true clinical throat swab specimens by
Nanorod Array-Surface-Enhanced Raman Spectroscopy. PLoS One. 5(10):e13633.
http://dx.plos.org/10.1371/journal.pone.0013633. PMID: 21049032
*
68. Cloward, J.M. and D.C. Krause. 2010. Functional domain analysis of the Mycoplasma pneumoniae
co-chaperone TopJ. Molec. Microbiol. 77:158-169. PMID: 20487283
*
69. Lai, J.-F., C.L. Zindl, L.B. Duffy, T.P. Atkinson, Y.W. Jung, N. Van Rooijen, K.B. Waites, D.C.
Krause, and David D. Chaplin. 2010. Critical role of macrophages and their activation via MyD88NFκB signaling in lung innate immunity to Mycoplasma pneumoniae. PLoS ONE 5(12): e14417.
doi:10.1371/journal.pone.0014417 PMID: 21203444
*
70. Chang, H.-Y., J.L. Jordan, and D.C. Krause. 2011. Domain analysis of protein P30 in Mycoplasma
pneumoniae cytadherence and gliding motility. J. Bacteriol. 193:1726-1733. PMID: 21257768
*
71. Cloward, J.M. and D.C. Krause. 2011. Loss of co-chaperone TopJ impacts adhesin P1 presentation
and terminal organelle maturation in Mycoplasma pneumoniae. Molec. Microbiol. 81:528-539.
PMID: 21631602
*
72. Chang, H.-Y. and D.C. Krause. 2011. Processing is required for a fully functional protein P30 in
Mycoplasma pneumoniae cytadherence. J. Bacteriol. 193:5841-5846. PMID: 21821772
*
73. Hennigan, S.L., J.D. Driskell, N. Ferguson-Noel, R.A. Dluhy, Y. Zhao, R.A. Tripp, and D.C. Krause.
2012. Detection and differentiation of avian mycoplasmas by surface-enhanced Raman spectroscopy
5
based on silver nanorod array.Appl. Env. Microbiol. 78:1930-1935. PMID:22210215
74. Szczepanek, S.M., S. Majumder, E.S. Sheppard, X. Liao, D. Rood, E.R. Tulman, S. Wyand, D.C.
Krause, L.K. Silbart, and S.J. Geary. 2012. Vaccination of BALB/c mice with avirulent
Mycoplasma pneumoniae P30 mutants results in disease exacerbation upon challenge with a virulent
strain. Infect. Immun. 80:1007-1014. PMID:22252865
*
75. Hasselbring, B.M., E.S. Sheppard, and D.C. Krause. 2012. P65 Truncation impacts P30 dynamics
during Mycoplasma pneumoniae gliding motility. J. Bacteriol. 194:3000-3007. PMID:22544269.
*
76. Page, C.A. and D.C. Krause. 2013. Gliding motility in Mycoplasma pneumoniae correlates with
reversible phosphorylation of terminal organelle proteins. Submitted.
*
Book Chapters:
1. Krause, D. C. and D. Taylor-Robinson. 1992. Mycoplasma which infect humans. In: Mycoplasmas:
Molecular Biology and Pathogenesis. (Maniloff, J., R. N. McElhaney, L. R. Finch, and J. B.
Baseman, eds). American Society for Microbiology, Washington, D.C. pp. 417-444.
2. Krause, D. C. and M. K. Stevens. 1995. Localization of antigens on mycoplasma cell surface and tip
structures. In: Molecular and Diagnostic Procedures in Mycoplasmology, Vol. I. (S. Razin and J. G.
Tully, eds). Academic Press, Inc., Orlando, FL, pp. 89-98.
3. Greene, C.E. and D.C. Krause. 2000. Bartonellosis. In: Emerging Infectious Diseases of Animals. (C.
Brown and C. Bolin, ed.). American Society for Microbiology, Washington, D.C.
4. Balish, M.F. and D.C.Krause. 2002. Cytoskeletal structure and function in Mycoplasma pneumoniae.
In: Molecular Biology and Pathogenicity of Mycoplasmas. (S. Razin and R. Herrmann, ed.).Kluwer
Academic / Plenum Publishers, New York, pp. 491-518.
5. Balish, M.F. and D.C. Krause. 2005. Mycoplasma attachment organelle and cell division; p. 189-237.
In: Mycoplasmas: Molecular biology, Pathogenicity, and strategies for control; A. Blanchard and G.
Browning, eds. Horizon Scientific Press, Norfolk, UK..
6. Krause, D.C., J.L. Jordan, H-Y. Chang, H.K. Park, and T.M. Krunkosky. 2007. Mycoplasma
pneumoniae attachment and colonization of the respiratory mucosa. In: Virulence Mechanisms of
Bacterial Pathogens, 4th Ed, Brogden, K.A., F.C. Minion, T.B. Stanton, Q. Zhang, L. Nolan, and M.
J. Wannemuehler, eds. ASM Press, Washington, D.C. pp 135-147.
7. Driskell, J.D., S. Shanmukh, Y. Liu, S. Chaney, S. Hennigan, L. Jones, D.C. Krause, R.A. Tripp, Y.-P.
Zhao, and R.A. Dluhy. 2008. Novel Nanoarray SERS Substrates Used for High Sensitivity Virus
Biosensing and Classification. Nanoscience and Nanotechnology for Chembio Defense; Ramanathan,
Ed.; ACS. In press.
Patents:
1. Patent No. 7,889,334 issued February 15, 2011. “Surface Enhanced Raman Spectroscopy (SERS)
Systems for the Detection of Bacteria and Methods of Use Thereof”. Inventors: R.A. Dluhy, J.
Driskell, S.M.L. Hennigan, D.C. Krause, R.A. Tripp, and Y. Zhao.
Abstracts:
1. Krause, D. C. and J. B. Baseman. Mycoplasma pneumoniae proteins that selectively bind to host
cells. Texas Branch, American Society for Microbiology. San Antonio, Texas. September, 1981.
2. Krause, D. C. and J. B. Baseman. Mycoplasma pneumoniae proteins that selectively bind to host
cells. 82nd annual meeting, American Society for Microbiology. Atlanta, Georgia. March, 1982.
3. Krause, D. C., H. H. Winkler and D. O. Wood. Cloning of Rickettsia prowazekii genes into
Escherichia coli. American Society for Rickettsiology, Airlie, Virginia. October 27-30, 1983.
6
4. Krause, D. C., H. H. Winkler and D. O. Wood. Expression of Rickettsia prowazekii Antigens in
Escherichia coli. 84th annual meeting, American Society for Microbiology. St. Louis, Missouri.
March, 1984.
5. Krause, D. C., H. H. Winkler and D. O. Wood. Cloning and expression of the Rickettsia prowazekii
ADP/ATP translocator in Escherichia coli. Eighth Annual Mid-Atlantic Regional Extrachromosomal
Genetic Elements Meeting. Virginia Beach, Virginia. October 12-14, 1984.
6. Krause, D. C., H. H. Winkler and D. O. Wood. Cloning and expression of the Rickettsia prowazekii
ADP/ATP translocator in Escherichia coli. American Society for Rickettsiology. Laguna Beach,
California. March 1-3, 1985.
7. Williamson, L. R., D. C. Krause and D. O. Wood. Sequencing the ADP/ATP translocase gene of
Rickettsia prowazekii. American Society for Rickettsiology. Williamsburg, Virginia. November,
1985.
8. Chen, Y.-Y. and D. C. Krause. Mycoplasma pneumoniae parasitism of host epithelial cells.
Southeastern Microbial Physiology and Genetics Conference. Maggie Valley, North Carolina.
October 23-25, 1987.
9. Faust, K. E., M. K. Stevens and D. C. Krause. Cloning and expression of Mycoplasma pneumoniae
cytadherence-associated protein HMW3 in Escherichia coli. 88th annual meeting of the American
Society for Microbiology. Miami Beach, Florida. May 8-13, 1988.
10. Stevens, M. K., K. E. Faust and D. C. Krause. Characterization of Mycoplasma pneumoniae
cytadsorption accessory proteins HMW1-4. 88th annual meeting of the American Society for
Microbiology. Miami Beach, Florida. May 8-13, 1988.
11. Krause, D. C. Opal suppression and the expression of Mycoplasma pneumoniae genes in
Escherichia coli. 7th Congress of the International Organization for Mycoplasmology. Baden,
Austria. June, 1988.
12. Krause, D. C. and Y.-Y. Chen. Oxidative stress response and Mycoplasma pneumoniae toxicity for
tracheal epithelium. 7th Congress of the International Organization for Mycoplasmology. Baden,
Austria. June, 1988.
13. Krause, D. C. and C. B. Mawn. Physical analysis and mapping of the Mycoplasma pneumoniae
chromosome. 89th annual meeting of the American Society for Microbiology. New Orleans,
Louisiana. May 14-18, 1989.
14. Stevens, M. K. and D. C. Krause. Analysis of the composition and structure of the cytoskeletonlike network of Mycoplasma pneumoniae. Southeastern Microbial Physiology and Genetics
Conference. Hendersonville, North Carolina. September 15-17, 1989.
15. Ogle, K. F. and D. C. Krause. Molecular characterization of the cytadherence phase-variable protein
HMW3 of Mycoplasma pneumoniae. Southeastern Microbial Physiology and Genetics Conference.
Hendersonville, North Carolina. September 15-17, 1989.
16. Ogle, K. F., K. K. Lee and D. C. Krause. Localization and restriction mapping of the hmw3 gene
from wild-type and cytadherence-variant Mycoplasma pneumoniae. 90th annual meeting of the
American Society for Microbiology. Anaheim, California. May 13-17, 1990.
17. Stevens, M. K. and D. C. Krause. Analysis of the composition and structure of the cytoskeleton-like
network of Mycoplasma pneumoniae. 90th annual meeting of the American Society for
Microbiology. Anaheim, California. May 13-17, 1990.
18. Krause, D. C., K. F. Ogle, M. K. Stevens and K. K. Lee. Genetic and biochemical analysis of
cytadherence phase variation in Mycoplasma pneumoniae. 8th Congress of the International
Organization for Mycoplasmology. July 8-12, 1990.
19. Krause, D. C. and K. K. Lee. Juxtaposition of the genes encoding Mycoplasma pneumoniae
cytadherence-accessory proteins HMW1 and HMW3. 91st annual meeting of the American Society
for Microbiology. Dallas, Texas. May 5-9, 1991.
7
20. Krause, D. C., K. F. Ogle and M. K. Stevens. Mycoplasma pneumoniae cytadherence: the tie that
binds is more than skin-deep. IOM Letters 2:58. 9th International Congress of the International
Organization for Mycoplasmology. Ames, Iowa. August 2-7, 1992.
21. Barsh, L. B. and D. C. Krause. Protein phosphorylation in Mycoplasma pneumoniae. IOM Letters
2:340. 9th International Congress of the International Organization for Mycoplasmology. Ames,
Iowa. August 2-7, 1992.
22. Hedreyda, C., K. K. Lee and D. Krause. Transformation of Mycoplasma pneumoniae with Tn4001
by electroporation. 93rd General Meeting of the American Society for Microbiology. Atlanta,
Georgia. May 16-20, 1993.
23. Fuqua-Norman, A., P. Jameson, C. Greene, D. C. Krause and R. Regnery. Differentiation of
Rochalimaea isolates at the species level by polymerase chain reaction-restriction fragment length
polymorphism. 11th Meeting of the American Society for Rickettsiology and Rickettsial Diseases.
St. Simons Island, Georgia. September 17-20, 1994.
24. Romero-Arroyo, C. and D. C. Krause. 1995. Genetic complementation of a Mycoplasma
pneumoniae cytadherence-negative variant lacking the putative adhesin P30. 95th General Meeting of
the American Society for Microbiology. Washington, D.C. May 21-25, 1995.
25. Hedreyda, C. T. and D. C. Krause. 1995. Identification of a possible regulatory locus for
cytadherence phase variation in Mycoplasma pneumoniae. 95th General Meeting of the American
Society for Microbiology. Washington, D.C. May 21-25, 1995.
26. Hahn, T.-W. and D. C. Krause. 1995. Use of a transposon delivery vector to study function and
regulation of cytadherence-accessory proteins in Mycoplasma pneumoniae. 95th General Meeting of
the American Society for Microbiology. Washington, D.C. May 21-25, 1995.
27. Popham, P. L., K. A. Krebes and D. C. Krause. 1996. Post-translational regulation of cytadherence
accessory proteins HMW1 and HMW3 in a cytadherence-deficient mutant of Mycoplasma
pneumoniae. 96th General Meeting of the American Society for Microbiology. New Orleans, LA.
May, 1996.
28. James, S. R., M. Farmer, and D. C. Krause. 1996. Visual and digital image analysis of wild type
and mutant Mycoplasma pneumoniae cell morphology. 11th International Congress of the
International Organization for Mycoplasmology. Orlando, FL. July 14-19, 1996.
29. Arnett, E. A., T.-W. Hahn and D. C. Krause. 1996. Chloramphenicol acetyltransferase as a
selectable marker and reporter in Mycoplasma pneumoniae. 11th International Congress of the
International Organization for Mycoplasmology. Orlando, FL. July 14-19, 1996.
30. Popham, P. L., C. E. Romero-Arroyo and D. C. Krause. 1996. Transcription analysis of the hmw
operon of Mycoplasma pneumoniae. 11th International Congress of the International Organization for
Mycoplasmology. Orlando, FL. July 14-19, 1996.
31. Hahn, T.-W., C. E. Romero-Arroyo, and D. C. Krause. 1997. Topological analysis of HMW1 and
evidence for its requirement in Mycoplasma pneumoniae cytadherence. 97th General Meeting of the
American Society for Microbiology. Miami Beach, FL. May, 1997.
32. Birkhead, K. and D. C. Krause. 1997. Immunolocalization and regulation of the surface protein P65
of Mycoplasma pneumoniae. 97th General Meeting of the American Society for Microbiology.
Miami Beach, FL. May, 1997.
33. Romero-Arroyo, C. E., S. R. James, M. Farmer and D. C. Krause. 1997. Does loss of the putative
cytadherence protein P30 confer a developmental defect in Mycoplasma pneumoniae? 97th General
Meeting of the American Society for Microbiology. Miami Beach, FL. May, 1997.
34. Mehock, J., C. Greene, F. Gherardini, and D. Krause. 1997. In vitro analysis of feline erythrocyte
invasion by Bartonella henselae. 13th Sesqui-annual Meeting of the American Society for
Rickettsiology. Seven Springs, PA. September, 1997.
35. Ricci, A. M. and D.C. Krause. 1998. Synthesis and detection of recombinant green fluorescent
protein in Mycoplasma pneumoniae. 98th General Meeting of the American Society for Microbiology.
Atlanta, GA. May, 1998.
8
36. Fisseha, M., P. Popham, K. Birkhead, and D.C. Krause. 1998. Exploring HMW1 and HMW2
function in Mycoplasma pneumoniae. 12th Congress of the International Organization for
Mycoplasmology. Sydney, Australia, July 22-28.
37. Willby, M.J. and D.C. Krause. 1999. Proteolytic targeting associated with the C-terminus of the
Mycoplasma pneumoniae cytadherence-accessory protein HMW1. 99th General Meeting of the
American Society for Microbiology. Chicago, IL. May 30-June 3.
38. Fisseha, M. and D.C. Krause. 1999. Functional analysis of the hmw2 gene products in Mycoplasma
pneumoniae. 99th General Meeting of the American Society for Microbiology. Chicago, IL. May 30June 3.
39. Balish, M.F. and D.C. Krause. 2000. Stabilization of Mycoplasma pneumoniae HMW1 protein by
interactions with the cytoskeleton and the cell surface. 100th General Meeting of the American
Society for Microbiology. Los Angeles, CA. May 21-25.
40. Willby, M.J. and D.C. Krause. 2000. Insertional inactivation of the hmw3 gene of Mycoplasma
pneumoniae. 13th Congress of the International Organization for Mycoplasmology. Fukuoka, Japan,
July 14-19.
41. Ross, S.M., M.F. Balish, M. Fisseha, and D.C. Krause. 2001. Expression of truncated HMW2 in
Mycoplasma pneumoniae results in sharply reduced levels of other cytadherence accessory proteins.
101st General Meeting of the American Society for Microbiology. Orlando, FL. May 20-24.
42. Jordan, J.L. and D.C. Krause. 2001. Mycoplasma pneumoniae cytadherence and gliding motility:
dual functions distinguishable for protein P30. 101st General Meeting of the American Society for
Microbiology. Orlando, FL. May 20-24.
43. Santurri, R.T. and D.C. Krause. 2001. Localization of HMW2 in Mycoplasma pneumoniae by
green fluorescent protein fusion. 101st General Meeting of the American Society for Microbiology.
Orlando, FL. May 20-24.
44. Chenoweth, M.R., C.E. Greene, D.C. Krause, and F.C. Gherardini. 2001. 101st General Meeting of
the American Society for Microbiology. Orlando, FL. May 20-24.
45. Balish, M.F., R.T. Santurri, K.K. Lee, and D.C. Krause. 2002. 14th Congress of the International
Organization for Mycoplasmology. Vienna, Austria, July 7-12.
46. Waldo, R.H. III, M.F. Balsih, M.J. Willby, S.M. Ross, and D.C. Krause. 2002. 14th Congress of the
International Organization for Mycoplasmology. Vienna, Austria, July 7-12.
47. Balish, M.F., J. Hegermann, G. Smith, J.T. Regula, R. Herrmann, C.A. Hutchison, III, and D.C.
Krause. 2003. FtsZ and a model for the evolution of cell division in the Mollicutes. 103rd General
Meeting of the American Society for Microbiology, Washington, DC May 18-22.
48. Ross, S.M., M.F. Balish, M. Fisseha, and D.C. Krause. 2003. Deletion analysis of Mycoplasma
pneumoniae Cytadherence-Associated Protein HMW2 suggests a role for the C-terminus in protein
bundling. 103rd General Meeting of the American Society for Microbiology, Washington, DC May
18-22.
49. Howard, E., J.L. Jordan, and D.C. Krause. 2003. Functional analysis of a P30-GFP fusion in
Mycoplasma pneumoniae. 103rd General Meeting of the American Society for Microbiology,
Washington, DC May 18-22.
50. Jordan, J.L. and D.C. Krause. 2003. Deletion analysis for functional domains of Mycoplasma
pneumoniae cytadherence-associated protein P30. 103rd General Meeting of the American Society
for Microbiology, Washington, DC May 18-22.
51. Chenoweth, M.R., G.A. Somerville, D.C. Krause, and F.C. Gherardini. 2003. Growth
Characteristics of Bartonella henselae in Liquid Culture. 103rd General Meeting of the American
Society for Microbiology, Washington, DC May 18-22.
52. Jordan, J.L., M.F. Balish, L.S. Holt, S.M. Ross, and D.C. Krause. 2004. Mycoplasma pneumoniae
protein P200 is an attachment organelle protein required for wild-type gliding motility but not for
cytadherence. 104th General Meeting of the American Society for Microbiology, New Orleans, LA.
9
53. Balish, M.F., K.K. Lee, M.J. Willby, and D.C. Krause. 2004. Structure-function analysis of
Mycoplasma pneumoniae cytadherence-accessory protein HMW1 reveals distinct relationships with
P1 and HMW2. 104th General Meeting of the American Society for Microbiology, New Orleans, LA.
54. Waldo, R.H. III, J. Jordan, and D.C. Krause. 2004. Identification and Complementation of a
Mutation in the Gene Encoding Mycoplasma pneumoniae Virulence Specific Proteins B and C. 104th
General Meeting of the American Society for Microbiology, New Orleans, LA.
55. Hasselbring, B.M., J.L. Jordan, L. B. Sellers, and D.C. Krause. 2004. Characterization of Gliding
Motility in Mycoplasma pneumoniae by Micro-cinematography and Mutant Analysis. 104th General
Meeting of the American Society for Microbiology, New Orleans, LA.
56. Jordan, J.L., T. M. Krunkosky, and D.C. Krause. 2004. In vitro cytadherence and localization studies
of wild-type Mycoplasma pneumoniae using a fully differentiated normal human bronchial epithelium
model. 15th Congress of the International Organization for Mycoplasmology. Athens, GA, USA July
10-16.
57. Balish, M.F., K.K. Lee, M.J. Willby, S.M. Ross, and D.C. Krause. 2004. Identification of distinct
functional regions of Mycoplasma pneumoniae cytadherence-accessory protein HMW1 through
deletion analysis. 15th Congress of the International Organization for Mycoplasmology. Athens, GA,
USA July 10-16.
58. Hasselbring, B.M., J.L. Jordan, L.B. Sellers, E.S. Sheppard, and D.C. Krause.
2004.
Characterization of gliding motility in Mycoplasma pneumoniae by microcinematography and mutant
analysis. 15th Congress of the International Organization for Mycoplasmology. Athens, GA, USA
July 10-16.
59. Hasselbring, B.M., J. L. Jordan, R. W. Krause, E. S. Sheppard, and D.C. Krause. 2004.
Quantification and Characterization of Gliding Motility in Mycoplasma pneumoniae by
Microcinematography and Mutant Analysis. American Society for Cell Biology. Washington, DC,
December 5-8.
60. Hasselbring, B.M., E. S. Sheppard, and D.C. Krause. 2005. Loss of Mycoplasma pneumoniae
Proteins P65 and P41 by Transposon Mutagenesis Implicates Functional Roles in Cytadherence,
Gliding Motility, and Cell Morphology. 105th General Meeting of the American Society for
Microbiology, Atlanta, GA, June 2005.
61. Ross, S.M. and D.C. Krause. 2005. Analysis by Electron Microscopy of Electron-Dense Core
Formation in Mycoplasma pneumoniae. 105th General Meeting of the American Society for
Microbiology, Atlanta, GA, June 2005.
62. Hasselbring, B.M., C.A. Page, and D.C. Krause. 2005. Mutant Analysis of Mycoplasma pneumoniae
Gliding Motility. 105th General Meeting of the American Society for Microbiology, Atlanta, GA,
June 2005.
62. Chang, H.-Y. and D.C. Krause. 2006. Mutant Analysis Suggests Transmembrane Domain may be
Important in P30 Function in Mycoplasma pneumoniae. 106th General Meeting of the American
Society for Microbiology, Orlando, FL, May 2006.
63. Hasselbring, B. M., E. S. Sheppard, and D. C. Krause. 2006. Mycoplasma pneumoniae cytoskeletal
element P65 anchors adhesin P30 at the terminal organelle during cell gliding. 16th Congress of the
International Organization for Mycoplasmology. Cambridge, UK, July 9-14.
64. Hasselbring, B.M., J.L. Jordan, R.W. Krause, and D.C. Krause. 2006. Terminal organelle
development in Mycoplasma pneumoniae. 16th Congress of the International Organization for
Mycoplasmology. Cambridge, UK, July 9-14.
65. Hasselbring, B.M. and D.C. Krause. 2006. Mutant analysis establishes that gliding motility in
Mycoplasma pneumoniae is mediated exclusively by the terminal organelle. 16th Congress of the
International Organization for Mycoplasmology. Cambridge, UK, July 9-14.
66. Hasselbring, B.M. and D.C. Krause. 2007. Cell-independent gliding by the terminal organelle of the
wall-less prokaryote Mycoplasma pneumoniae. IX Bacterial Locomotion and Signal Transduction
Conference, Laughlin, NV, January 14-19.
10
67. Cloward, J. and D.C. Krause. 2007. Characterization of a Mycoplasma pneumoniae CytadherenceAssociated J-Domain Protein. 107th General Meeting of the American Society for Microbiology,
Toronto, Canada. May 21-25.
68. Hennigan, S.L., R. Dluhy, J. Driskell, Y.P. Zhao, S.H. Kleven, R.A. Tripp, and D.C. Krause. 2008.
Detection and differentiation of Mycoplasma pneumoniae and Mycoplasma gallisepticum strains by
nanorod array surface enhanced Rama spectroscopy. 17th Congress of the International Organization
for Mycoplasmology. Tianjin, China. July 6-11.
69. Chang, H.-Y. and D.C. Krause. 2008. Structure-function analysis reveals roles for P30 cytoplasmic
and C-terminal domains in Mycoplasma pneumoniae. 17th Congress of the International Organization
for Mycoplasmology. Tianjin, China. July 6-11.
70. Cloward, J. M. and D.C. Krause. 2008. A Mycoplasma pneumoniae J-domain protein required for
cell divisionand cytadherence. 17th Congress of the International Organization for Mycoplasmology.
Tianjin, China. July 6-11.
71. Page, C.A. and D.C. Krause. 2008. Gliding motility in Mycoplasma pneumoniae is dependent upon a
protein kinase/phosphatase pair. 17th Congress of the International Organization for Mycoplasmology.
Tianjin, China. July 6-11.
72. Cloward, J.M. and D.C. Krause. 2009. TopJ assists in coordinating terminal organelle formation and
cell division in Mycoplasma pneumoniae. 109th General Meeting of the American Society for
Microbiology, Philadelphia, PA. May 17-21.
73. Dluhy, R.A., J. D. Driskell, Y.-P. Zhao, P. Rota, R. Tripp, and D.C. Krause. 2009. Novel Nanorod
Array Substrates as a Platform for SERS-Based Biosensing of Infectious Disease. 238th American
Chemical Society National Meeting, Washington, DC, August 16-20.
74. Krause, D.C., J. Cloward, and B. M. Hasselbring. 2009. Terminal Organelle Form and Function in
Mycoplasma pneumoniae Gliding Motility. Symposium on Bacterial Cell Biology and pathogenesis,
Umeå, Sweden, June 2009.
75. Chang, H.-Y. and D.C. Krause. 2010. Post-translational processing is required for a fully
functional P30 in Mycoplasma pneumoniae. 110th General Meeting of the American Society for
Microbiology, San Diego, CA. May 23-27.
76. Chang, H.-Y. and D.C. Krause. 2010. Post-translational processing is required for a fully
functional P30 in Mycoplasma pneumoniae. 18th Congress of the International Organization for
Mycoplasmology. Chianciano Terme, Italy. July 11-16.
77. Hennigan, S.L., J. Driskell, Y. Zhao, R.A. Dluhy, R.A. Tripp, K.B. Waites and D.C. Krause. The
Detection of Mycoplasma pneumoniae clinical samples using a silver nanorod array biosensing
platform with surface-enhanced Raman spectroscopy. FACSS 2010 conference, Raleigh, NC,
October, 2010.
78. Page, C.A. and D.C. Krause. 2011. Mutant Analysis Reveals Correlation between Gliding Motility
and Protein Phosphorylation in Mycoplasma pneumoniae. XI Bacterial Locomotion and Signal
Transduction Conference, New Orleans, LA. January 16-21.
79. Cowart, K., S.L. Hennigan, Y. Zhao, R.A. Dluhy, R.A. Tripp, K.B. Waites and D.C. Krause. 2012.
Nanorod array-surface enhanced Raman spectroscopy as a highly sensitive and specific method for
the detection of Mycoplasma pneumoniae in a complex biochemical background. 4th Annual Georgia
Symposium on Nanotechnology and Infectious Diseases. April 2, 2012.
80. Cowart, K., S.L. Hennigan, Y. Zhao, R.A. Dluhy, R.A. Tripp, K.B. Waites and D.C. Krause. 2012.
Nanorod array-surface enhanced Raman spectroscopy as a highly sensitive and specific method for
the detection of Mycoplasma pneumoniae in a complex biochemical background. 19th Congress of the
International Organization for Mycoplasmology. Toulouse, France. July 2012.
81. Prince, O.A., T. Krunkosky, and D.C. Krause. Modeling human airway colonization by Mycoplasma
pneumoniae. 19th Congress of the International Organization for Mycoplasmology. Toulouse, France.
July 2012.
11
Invited Seminars (since 1985)
1. University of Georgia Parasitology Seminar Series; November 1985
2. University of Georgia Department of Medical Microbiology; February 1987
3. Emory University Department of Microbiology; September 1988
4. University of North Carolina Department of Microbiology and Immunology; October 1989
5. East Carolina University Department of Microbiology and Immunology; October 1990
6. Morehouse College School of Medicine; February 1991
7. Louisiana State University - Shreveport Dept of Microbiology and immunology; May 1991
8. University of Texas Health Science Ctr at San Antonio Dept of Microbiology, October 1992
9. Emory University Department of Microbiology; November 1994
10. American Society for Microbiology Divisional Lecturer; May 1996
11. Iowa State University VMRI; October 1997
12. University of Alabama at Birmingham Department of Comparative Medicine; February 1998
13. SE Branch, American Society for Microbiology; October 1998
14. University of Georgia Dept. of Biochem. and Molecular Biology Winter Symposium; April 1999
15. Society for General Microbiology, Leeds, England; September 1999
16. University of Florida; January 2000
17. NIH Rocky Mountain Laboratories; September 2000
18. University of Montana Department of Biology; September 2000
19. University of Texas Medical School; November 2000
20. University of Connecticut School of Medicine; January 2001
21. Georgia State University; March 2001
22. University of Vienna, Austria; October 2001
23. University of Georgia Department of Medical Microbiology; January 2002
24. University of South Alabama College of Medicine; February 2002
25. American Society for Microbiology, May 2002
26. University of Texas Health Science Center at San Antonio, October 2002
27. Auburn University, November 2002
28. Clayton State University, February 2003
29. Athens Regional Medical Center, February 2005
30. Society for General Microbiology, Keele, England; September 2005
31. University of Florida, November 2005
32. University of North Texas Health Science Center, December 2005
33. University of Georgia, June, 2006
34. 16th Congress of the International Organization for Mycoplasmology, Cambridge, UK, July 2006
35. 4th Internat. Symp. on Virulence Mechanisms of Bacterial Pathogens, Ames, IA, September 2006
36. University of Delaware, November 2007
37. Valdosta State University, February 2008
38. Gordon Conference on Acute Respiratory Infection; Ventura, CA, March, 2008
39. North Carolina State University, April, 2008
40. American Society for Microbiology 108th General Meeting, Boston, MA, June, 2008
41. Mycoplasma Techniques Workshop. July 6, 2008; Tianjin, PRC
42. Center for Drug Discovery; University of Georgia, November 2008
43. Symposium on Bacterial Cell Biology and Pathogenesis; Umeå, Sweden, June 2009
44. Mercer University College of Pharmacy and Health Sciences, December 2009
45. Ohio State University, October 2010
46. Nanoscale Science and Engineering Center, University of Georgia, November 2009
47. Cold Spring Harbor Conference on Molecular Pathogenesis and Host Response, September 2011
48. Wake Forest University, October 2011.
49. Clemson University, January 2012.
12
50.
51.
52.
53.
Emory University, March 2012.
University of Georgia Department of Infectious Diseases, March 2012.
19th Congress of International Organization for Mycoplasmology. Toulouse, France. July 2012.
University of North Carolina at Chapel Hill, May, 2013
Grant Awards:
Total Funding 1986-present: $8,447,701
Complete:
1. "Genetic Analysis of Mycoplasma pneumoniae Cell Adherence", University of Georgia Faculty
Research Grant; $5,000, December 1, 1985 - March 1, 1987.
2. "Mechanism of Mycoplasma pneumoniae Cytotoxicity for Respiratory Epithelium", the American
Lung Association, $34,763, July 15, 1986 - July 15, 1988.
3. "Cloning and Expression in E. coli of Mycoplasma gallisepticum Antigens Having
Diagnostic/Prophylactic Potential," University of Georgia Research Foundation, $28,940, November
1, 1987 - October 31, 1989. With S. H. Kleven, Co-P.I.
4. "Instrumentation for a Biological Sequence and Structure Computational Facility. National Science
Foundation, $277,931. May, 1988 - April, 1989. One of 48 contributors.
5. "Cytoskeletal Organization in the Prokaryote Mycoplasma pneumoniae", University of Georgia
Faculty Research Grant; $4,500, March 1, 1989 - May 1, 1990.
6. “A Genetic Approach to Mycoplasma pneumoniae Virulence"; The National Institutes of Health,
$68,580 (year 05), September 1, 1990 - August 31, 1995. Research Career Development Award.
7. "Protein Phosphorylation in Mycoplasma pneumoniae," The National Institutes of Health, $61,315
(year 04), January 1, 1993 - September 30, 1997.
8. “Vaccine Development for Cat Scratch Disease: Outer Membrane Proteins of Bartonella henselae”,
University of Georgia Program in Biological Resources and Biotechnology, $32,125 (year 01), July 1,
1996 - June 30, 1998.
9. "Molecular Cell Biology of Parasites and Vectors" (Training Grant), the National Institutes of Health,
$148,033 (year 09), September 1, 1987 - August 31, 1998, one of eighteen participants.
10. "Prokaryotic Diversity - An Organismal Approach," National Science Foundation, $364,897 (year
02), October 1, 1994 - September 30, 1999. Research Training Group; one of 23 faculty.
11. “FtsZ and Mycoplasma pneumoniae Cell Division”, The National Institutes of Health, $39,232 (total
cost, year 03, April 1, 2000-March 31, 2003. NRSA to Mitchell Balish.
12. “15th Congress of the International Organization for Mycoplasmology” – The National Institutes of
Health Conference grant, 07/11/2004-07/16/2004; Role: PI / Conference chair; $12,000 direct costs
13. “15th Congress of the International Organization for Mycoplasmology” – U.S. Department of
Agriculture Conference grant, 07/11/2004-07/16/2004; Role: Co- PI (with Stan Kleven, Avian
Medicine); $10,000 direct costs
14. “16th Congress of the International Organization for Mycoplasmology” – The National Institutes of
Health Conference grant, 07/9/2006-07/14/2006; Role: PI; $10,000 direct costs
15. “17th Congress of the International Organization for Mycoplasmology” – The National Institutes of
Health Conference grant, 07/6/2008-07/11/2008; Role: PI; $10,000 direct costs
16. “Detection / Identification of Mycoplasmas in Poultry by Nanorod Array SERS”, VMES $15,000;
5%; July 1, 2007-May 31, 2008.
17. “18th Congress of the International Organization for Mycoplasmology” – The National Institutes of
Health Conference Grant, 07/11/2010-07/16/2010; Role: PI; $12,000 direct costs
18. "Genetic Analysis of Mycoplasma pneumoniae Cell Adherence", National Institutes of Health.
August 1986-May 2010.
19. “USDA-UGA Cooperative Agreement on Developing One Health Business Plan”; USDA. July 2011May 2012. $3000 direct costs
13
Active:
1. “Mycoplasma pneumoniae Gliding Motility”, The National Institutes of Health, $351,000 (year 06)
June 1, 2002-July 31, 2013.
2. “Mycoplasma pneumoniae Gliding Motility”, The National Institutes of Health, $91,712 (total costs)
July 1, 2010-May 31, 2013. Research Supplement to Support Diversity in Health-Related Research
3. “Nanotechnology-Based Detection of Mycoplasma pneumoniae”, The National Institutes of Health
(R21-AI096364); August 1, 2012 – July 31, 2014; $425,138 total costs
Pending:
1. “Mycoplasma pneumoniae Induces Mucus Hypersecretion in Asthma by Inactivating FoxA2”, The
National Institutes of Health, July 1, 2013 – June 30, 2015; $275,000 total direct costs (G. Lau, PI)
Honors and Professional Service Positions:
1. Co-Program Chair, 1988 SE Microb. Physiol. & Genetics Conference, Maggie Valley, NC
2. Program Chair, 1989 SE Microbial Physiol. & Genetics Conference, Hendersonville, NC.
3. Chair-elect, American Society for Microbiology Division D-General Med. Microbiol. 1989
4. Chair, American Society for Microbiology Division D - General Med. Microbiology, 1990
5. Organizer, Division Group I symposium, ASM General Meeting, Anaheim, CA, May, 1990
6. Research Career Development Award, National Institutes of Health, 1990-1995
7. Editorial Board, Journal of Microbiological Methods, 1990-1994
8. Member (ad hoc), NIH Study Section/AIDS and Related Research B, February, 1992
9. Member, International Organization for Mycoplasmology International Research Program on
Comparative Mycoplasmology (IRPCM), working team for human and nonhuman primate
mycoplasmas. 1993-2002
10. ASM - Baxter Diagnostics Microscan Young Investigator Award Selection Committee; 1992-1994
11. Member, American Society for Microbiology Division G nominating committee. 1994
12. Chair-elect, American Society for Microbiology Division G - Mycoplasmology, 1996-1997
13. Divisional Lecturer, American Society for Microbiology Division G, May, 1996
14. Chair, IRPCM Board, Human Mycoplasma Pathogenesis Team. 1996-2002
15. Chair, American Society for Microbiology Division G, 1997-1998
16. Board Member, IRPCM 1998-2002
17. International Organization for Mycoplasmology (IOM) Program Committee, 1996-1998
18. University of Georgia Creative Research Medal, 1999
19. Chair, Program Committee, IOM, 2000-2002
20. Board of Directors, IOM, 2000-2004
21. Meeting Chair, 15th Congress of the IOM, 2002-2004
22. Member (ad hoc), NIH Bacteriology and Mycology 2 Study Section; February 2001; June 2003
23. Member, External Advisory Review Committee, Berkeley Structural Genomics Center, University of
California at Berkeley; 2001-2004
24. Biomedical and Health Sciences Institute Spring Symposium 2004: “Emerging Infectious Diseases –
Threats to the Southeastern U.S.”, March 3-5, 2004, Savannah, GA; Co-organizer, Scientific Program
25. Member (ad hoc), NIH Bacterial Pathogenesis Study Section; March 2005; June 2005
26. Alternate Councilor / Councilor, American Society for Microbiology Division G, 2007-2011.
27. Instructor, Mycoplasma Techniques Workshop, Tianjin Medical Univ., Tianjin, China, July 6, 2008.
28. Member (full), NIH Bacterial Pathogenesis Study Section (beginning October 2009)
29. Fellow, American Association for the Advancement of Science (December 2009-present)
30. Member, UGA Center for Drug Discovery Executive Committee; June 2011-present
31. Faculty Mentor, UGA CURO Honors Scholar Program, September 2011 - present
14
Membership in Professional Societies:
American Society for Microbiology
International Organization for Mycoplasmology
American Association for the Advancement of Science
15
Teaching Experience:
Course
Term(s)
Role
Location
1. General Microbiology for Nursing
Students
Winter 1980
Laboratory Instructor
Univ. of North Carolina
2. Medical Microbiology for Medical Students
Fall 1984
Contributing Lecturer
Univ. of South Alabama
3. Cell Biology for Graduate Students
Spring 1985
Contributing Lecturer
Univ. of South Alabama
4. Pathogenic Microbiology (MIBO4220)
Fall 1985 - Winter 1996, 1997
Spring 1998, 1999, Fall 1999
Contributing Lecturer
Course Instructor
Univ. of Georgia
5. Introduction to Microbiology (MIBO3500)
Spring 1988
Fall 1990
Fall 1996-2000
Spring 2002-05
Fall 2005-07
Course Instructor
Univ. of Georgia
6. Immunology (MIB 410)
Winter 1986- Fall 1995
Course Instructor
Univ. of Georgia
7. Organismal Biology (BIO 303)
Spring 1987
Contributing Lecturer
Univ. of Georgia
8. Molecular Mechanisms of Microbial
Pathogenesis (MIB 815)
Spring 1987, 1990, 1993, 1996
Course Instructor
Univ. of Georgia
9. Independent study & Honors
>30 students
Instructor
Univ. of Georgia
10. Micro Health Care (MIB 250; MIBO2500)
Winter 1988, 1989, 1991
Fall 2008- 2012
Course Instructor
Univ. of Georgia
11. Adv. Microbial Metabolism (MIB 861)
Spring 1988- Spring 1991
Contributing Lecturer
Univ. of Georgia
12. Seminar in Microbiology (MIB 816)
Spring 1989
Course Instructor
Univ. of Georgia
13. Fundamentals of Microbiology (MIB 409)
Fall 1988
Contributing Lecturer
Univ. of Georgia
14. Adv. Microbial Diversity (MIB 862)
Fall 1992
Contributing Lecturer
Univ. of Georgia
15. Exp. Path. Bacteriol. & Immunol.
(MIB 423/623)
Spring 1994- 1996
Course Instructor
Univ. of Georgia
16. Freshman Seminar (FRES1010)
Fall 2002 - 2005
Course Instructor
Univ. of Georgia
16