Nirit Lev M

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CURICULUM VITAE
Name:
NIRIT LEV, M.D.
Identification No.
024538738
Faculty
Sackler School of Medicine, Tel Aviv
University, Israel
Home Address
124/8 Uziel St., Ramat Gan, Israel
Tel:
03-5717625, 052-4373986
E-mail:
lev.nirit@gmail.com
Date of Birth
25/1/1970, Israel
Marital Status
Married + 2
Zahal Military service:
Intelligence, 1988-1990
A. Education:
2004-present
PhD in Neuroscience, Felsenstein Medical Research Center,
Sackler School of Medicine, Tel Aviv University, Israel
Supervisors: Prof. Eldad Melamed and Dr. Daniel Offen.
PhD thesis: “Molecular and biochemical mechanisms in the
pathogenesis of Parkinson’s disease”
1998-2004
Residency in Neurology, Rabin Medical Center, Campus
Beilinson, Petah-Tikva, Israel
2002
Laboratory of Neuroscience, FMRC, Sackler School of
Medicine, Tel-Aviv University (Advisor: Dr Daniel Offen)
1998
Laboratory of Neuroscience, Weizman Institute of Science
(Advisor: Prof. Z Vogel)
1990- 1997
Bachelor of Medicine and M.D., Sackler School of Medicine,
Tel Aviv University, Israel
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M.D. Thesis: “The prognostic significance of chest CT findings
1997
during diagnosis of Hodgkin disease” (Advisors: Dr. S Apter,
Prof. Ben Basat)
B. Academic and clinical experience:
2004-present Ph.D. in Neuroscience, Sackler School of Medicine, Tel-Aviv
University, Israel.
2004
Specialist Diploma in Neurology
2004
Instructor of Neurology, Sackler School of Medicine, Tel Aviv
University
1998-2004
Residency in the Department of Neurology, Rabin medical center,
Campus Beilinson, Petah-Tiqva, Israel.
2000-2004
Tutor of medical students in the clerkship of Neurology, Rabin
Medical center, Campus Beilinson, Petah-Tiqva, Israel.
1992-1996
Instructor and tutor of pre-clinical courses, New York program,
Sackler School of Medicine, Tel Aviv University, Israel.
1992
Anatomy instructor, Sackler School of Medicine, Tel Aviv University,
Israel.
C. Academic awards:
1987- Award for excellence for high school achievements
1989- Award for excellence during the military service, Intelligence, Zahal
1991- Dean award for outstanding academic achievements, Sackler School of
Medicine, Tel Aviv University
2
1991- The Anatomy award for excellence, Sackler School of Medicine, Tel Aviv
University
1992- Rector award for high academic achievements, Tel Aviv University
1993- The “Kneset” (the Israeli parliament) award for outstanding academic
achievements
1994- Dean award for high academic achievements, Sackler School of Medicine, Tel
Aviv University
1995- Dean award for high academic achievements, first of class for pre-clinical
studies, Sackler School of Medicine, Tel Aviv University
1996- Dean award for high academic achievements, Sackler School of Medicine, Tel
Aviv University
1997- Dean award for outstanding academic achievements, first of her class in the
medical school, Sackler School of Medicine, Tel Aviv University
1998- Doctor of Medicine (M.D.) diploma, Suma Cum Laude
2000- Outstanding resident award, Rabin Medical Center, Campus Beilinson, PetahTikva, Israel
2003- Excellence in the Neurological Internship Exam
2004- The young investigator award – The 20th annual meeting of the Israel
society of oxigen toxicity and free radical research, 12 December 2004.
D. Social activities:
1980-1987
Guide and active in the “Scouts”
1985-1986
Volunteer in “Magen David Adom”
1991-1992
“Education for health”, voluntary work with underprivileged youth
1992-1996
Volunteer in the “International Education Foundation” (ISEF)
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1996- Henri Glasberg award for voluntary work in the community, Tel Aviv
University
E. Membership in professional societies:
1999- present Israel Neurological association
2005-present Israel Society for Neuroscience
F. Active participation in scientific meetings:
1. The Annual Israel Neurologic Association Meeting, Tel Aviv, Israel,
June 1999.
2. The Annual Israel Neurologic Association Meeting, Tel Aviv, Israel,
November 1999.
3. The Annual Israel Neurologic Association Meeting, Zichron Yaakov,
Israel, November 2000.
4. European Neurological Society, Paris, France, April 2001.
5. 10th Congress of the International Headache Society and the American
Association for the study of Headache Scientific Meeting, New York,
USA, June 2001.
6. The Annual Israel Neurologic Association Meeting, Israel, November
2001.
7. The 7th International Congress of Parkinson’s Disease and Movement
Disorders, Miami, USA, November 2002.
8. The Annual Israel Neurologic Association Meeting, Israel, November
2002.
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9. Israel Society for Neuroscience 11th Annual Meeting and INMHA of
Canada/ISFN Joint Symposium, Eilat, Israel, December 2002.
10. The Annual Israel Neurologic Association Meeting, Israel, November
2003.
11. Israel Society for Neuroscience 13th Annual Meeting, Eilat, Israel,
November 2004.
12. The Annual Israel Neurologic Association Meeting, Tel Aviv, Israel,
December 2004.
13. The 20th annual meeting of the Israel society of oxigen toxicity and
free radical research, Jerusalem, Israel, December 2004.
14. ADPD 2005, Sorento Italy, March 2005.
15. Israel Society for Neuroscience 14th Annual Meeting, Eilat, Israel,
December 2005.
16. The Annual Israel Neurologic Association Meeting, Israel, Tel Aviv,
Israel, December 2005.
17. The 21th annual meeting of the Israel society of oxigen toxicity and
free radical research, Beer Sheva, Israel, January 2006.
18. The 58th annual meeting of the American Academy of Neurology, San
Diego, California, USA, April 2006.
G. Publications:
B.1. Original articles:
1. N Lev, S Maimon, ZH Rappaport, E Melamed, Spinal dural arteriovenous
fistulae – a diagnostic challenge. Isr Med Assoc J 2001;3(7):492-496.
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2. N Lev, Barhum Y, Melamed E, Offen D, Resistance of bax-deficient mice to
MOG-induced experimental autoimmune encephalomyelitis. Neuroscience
Lett 2004;359(3):139-42.
3. Y shoenfeld, S Lev, I blatt, M Blank M, J Font, P Von Landberg, N Lev, J
Zaech, R Cervera, JC Piette, ML Bertolaccini, GR Hughes, P Youinou et al.,
Features associated with epilepsy in the antiphospholipid syndrome. J
Rheumatol 2004;31(7):1344-8.
4. D Steiner, T Avidor-Reiss, E Schallmach, E Butovsky,N Lev, Z Vogel,
Regulation of adenylate cyclase type VIII splice variants by acute and chronic
Gi/o-coupled receptor activation. Biochem J. 2005;386(Pt 2):341-8.
5. D Shitrit, N Lev, Bar-Gil-Shitrit A, Kramer MR. Progressive multifocal
leukoencephalopathy in transplant recipients. Transpl Int. 2005;17(11):65865.
6. N Lev, S Lev, E Melamed, A Kuritzky, Heredity in menstrual migraine.
Cephalalgia (submitted)
7. N Lev, E Melamed, D Offen. Proteasomal inhibition hypersensitizes
differentiated neuroblastoma cells to oxidative damage. Neuroscience Lett
2006;399(1-2):27-32.
8. N Lev, D Ickowicz, Y Barhum, N Blondheim, E Melamed, D Offen.
Experimental encephalomyelitis induces changes in DJ-1: implications
for oxidative stress in Multiple Sclerosis. Antioxidants and Redox
Signaling 2006 (accepted).
B.2.Case reports:
1. N Lev, S Michowiz, E Inbar, CI Coire, S Pitlik, E Melamed,
Neurocysticercosis. Isr Med Assoc J 2002;4(1):65-66.
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2. D Shitrit, N Lev, SI Shiran, G Izbicki, D Sofer, E Melamed, MR
Kramer, Progressive multifocal leukoencephalopathy in a lung
transplanted patient. J Heart Lung Transplant 2003;22:946-950.
B.3. Reviews:
1. N Lev, S Maimon, E Melamed, E Inbar, Z Rappaport, Spinal dural
arteriovenous fistula. Harefua, 1999; 137(10):471-4.
2. N Lev, E Melamed, Sensory symptoms and pain in Parkinson disease.
Harefua, 2000; 138(4):324-6.
3. N Lev, E Melamed, Heredity in Parkinson’s disease: new findings. Isr Med
Assoc J 2001; 3(6):435-8.
4. N Lev, Melamed E, Neurological complications in Down’s syndrome.
Harefua 2002;141(9):820-823. (Hebrew)
5. R Djaldetti R, N Lev, E Melamed, Neuroprotection in progressive brain
disorders. Isr Med Assoc J 2003; 5(8): 576-80.
6. N Lev, E Melamed, D Offen, Apoptosis and Parkinson’s disease, Prog
Neuropsychopharmacol biol psychiatry, special topic: Apoptosis and Human
Neurodegenerative diseases, 2003; 27(2): 245-50.
7. N Lev, D Roncevic, D Ickwicz, E Melamed, D Offen. The role of DJ-1 in
Parkinson’s disease. J Mol Neurosc, 2006 (accepted).
B.4. Chapters in books:
1. N Lev, D Offen, E Melamed. Toxic causes of Parkinson’s disease.
Handbook of Neurology. In “Handbook of Clinical Neurology:
Parkinson's disease and related disorders”, edited by W. C. Koller and
E. Melamed 2006 (accepted).
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2. N Lev, Y Gilgun-Sherki, D Offen, E Melamed. Oxidative stress in
Multiple Sclerosis. The role of oxidative stress in the pathogenesis of
multiple sclerosis: Current state. In “Oxidative stress and neurological
disorders”, edited by Prof. G.A.Qureshi Elsevier books. To be publisged
in may 2006 (accepted).
D.2. Presentations at scientific meetings and conferences:
1. N Lev, S Maimon, E Melamed, Spinal dural arteriovenous fistula – a
diagnostic challenge. The Annual Israel Neurologic Association Meeting,
Tel Aviv, Israel, June 1999.
2. N Lev, D Steiner, T Avidor-Reiss, M Bayewitch, I Nevo, Z Vogel, Effect
of acute and chronic Gi/o coupled receptor activation on the activity of
tree splice variants of adenylyl cyclase type VIII. The Annual Israel
Neurologic Association Meeting, Tel Aviv, Israel, November 1999.
3. N Lev, S Lev, A Kuritaky, E Melamed, Heredity in menstrual migraine.
The Annual Israel Neurologic Association Meeting, Zichron Yaakov,
Israel, November 2000.
4. N Lev, S Lev, E Melamed, A Kuritzky, Heredity in menstrual migraine.
European Neurological Society, Paris, France, April 2001.
5. N Lev, S Lev, E Melamed, A Kuritzky, Heredity in menstrual migraine.
10th Congress of the International Headache Society and the American
Association for the study of Headache Scientific Meeting, New York,
USA, June 2001.
6. S Lev, N Lev, M Blank, Y Shoenfeld on behalf of the “Euro-APS study
group” (20 European centers), Characteristics of epileptic patients in the
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antiphospholipid syndrome (APS), The Annual Israel Neurologic
Association Meeting, Israel, November 2001.
7. N Lev, E Melamed, R Djaldetti, The effect of yohimbine on falls in
patients with Parkinson’s disease and parkinsonian syndromes. The 7th
International Congress of Parkinson’s Disease and Movement Disorders,
Miami, USA, November 2002.
8. N Lev, Barhum Y, Melamed E, Offen D, Resistance of bax-deficient mice
to MOG-induced experimental autoimmune encephalomyelitis. The
Annual Israel Neurologic Association Meeting, Israel, November 2002.
9. N Lev, Y Barhum, E Melamed, D Offen. Resistance of bax-deficient mice
to MOG-induced experimental autoimmune encephalomyelitis. Israel
Society for Neuroscience 11th Annual Meeting and INMHA of
Canada/ISFN Joint Symposium, Eilat, Israel, December 2002.
10. N Lev, E Melamed, D Offen. The role of proteasomal inhibition and
oxidative stress in alpha-synuclein aggregates induction in dopaminergic
neuronal cell lines. Israel Society for Neuroscience 13th Annual Meeting,
Eilat, Israel, 28-30 November 2004.
11. N Lev, E Melamed, D Offen. The role of proteasomal inhibition and
oxidative stress in alpha-synuclein aggregates induction in dopaminergic
neuronal cell lines. The Annual Meeting of the Israel Neurology
Association, Tel Aviv, Israel, 30 Nov-1 December, 2004.
12. N Lev, E Melamed, D Offen. Lewy body like aggregates induction by
oxidative stress-an in vitro model for Parkinson’s disease. The 20th
Annual Meeting of the Israel Society for Oxygen Toxicity and Free
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Radical Research, Hebrew University, Jerusalem, Israel December 12,
2004.
13. N Lev, E Melamed, D Offen. Proteasomal inhibition hypersensitizes
differentiated neuroblastoma cells to oxidative damage. 7th International
Conference on Alzheimer’s and Parkinson’s Diseases: Insights, Progress
and Perspectives. Sorrento, Italy, March 9-13, 2005.
14. N Lev, E Melamed, D Offen. Proteasomal inhibition and oxidative stress
induces alpha-synuclein aggregates in dopaminergic neuronal cell lines.
The sixth research fair of the Sackler faculty of medicine, April 20, 2005.
15. D Ickwicz , N Lev, E Melamed, D Offen. Oxidative stress induces DJ-1
changes in dopaminergic cells. Israel Society for Neuroscience 14th
Annual Meeting, Eilat, Israel, December 11-14, 2005.
16. N Lev, D Ickowicz, D Offen, E Melamed. The association of DJ-1 and
oxidative stress in the pathogenesis of Parkinson’s disease. The Annual
Meeting of the Israel Neurology Association, Tel Aviv, Israel, December
20-21, 2005.
17. N Lev, D Ickowicz, D Offen, E Melamed.Oxidative stress induced
changes in DJ-1 and the pathogenesis of Parkinson's disease. The 21th
Annual Meeting of the Israel Society for Oxygen Toxicity and Free
Radical Research, Ben Gurion University, Beer Sheva, Israel, January 1,
2006.
18. N Lev, D Ickowicz, D Offen, E Melamed. The Association of DJ-1 and
Oxidative Stress in the Pathogenesis of Parkinson’s Disease. The 58th
American Academy of Neurology Annual Meeting, April 1-8, 2006, San
Diego, California, USA.
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