1
Adil E. Bharucha, M.D.
Adil E. Bharucha, M.D.
Personal Information
Nationality:
Professional Address:
Telephone:
Fax:
Email address:
Indian; US Permanent Resident
Division of Gastroenterology and Hepatology
Mayo Clinic
200 First Street S.W.
Rochester, MN 55905
507-538-5854
507-538-5820
bharucha.adil@mayo.edu
Present Academic Rank and Position
Consultant, Division of Gastroenterology and Hepatology, Mayo Foundation, Rochester, MN, 2001
Director, Motility Interest Group, 2010
Associate Director, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.)
Program
Professor of Medicine, Mayo Clinic College of Medicine, Rochester, MN, 2007
Education
College
Medical School
Residency (1)
Internship
Residency (2)
Fellowship
Jai Hind College, Bombay, India
Seth G.S. Medical College, Bombay, India (1981-1987)
M.B.B.S. Degree
King Edward VII Memorial Hospital, Bombay, India (1987-1990)
M.D. (Medicine)
Sinai Hospital, Detroit, MI (1990-1991)
Department of Internal Medicine, Mayo Clinic College of Medicine,
Rochester, MN (1991-1993).
Division of Gastroenterology, Mayo Clinic College of Medicine, Rochester, MN
(1993-1996).
Research Fellowship, Division of Gastroenterology, Mayo Clinic
College of Medicine, Rochester, MN (with Dr. Michael Camilleri,
1994-1995)
Board Certification(s)
Diplomate
1993
1995
2006
American Board of Internal Medicine
American Board of Gastroenterology
American Board of Gastroenterology- recertification
Medical Licensure(s)
State of Minnesota
1991 (License #35341)
Other Examinations/Licensures
Maharashtra Medical Council
F.M.G.
FLEX
1990
1989
1991
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Adil E. Bharucha, M.D.
Honors/Awards
Honors Prize (1971-1978), Cathedral and John Connon School, Bombay
Distinction in Anatomy, 1st M.B.B.S. Examination, 1982
Annual Competitive Examination in Medicine, King Edward VII Memorial Hospital, 1986
Finalist, Clinical Vignette Competition at Annual Meeting of American College of Physicians, Washington, DC, 1993
J. Arnold Bargen Award for Outstanding Achievement by a Gastroenterology Trainee,
Mayo Clinic, Rochester, MN, 1996
4th Annual Young Investigator Award, Clinical Research. Functional Brain Research Group, 1999
1st IFFGD Junior Investigator-Clinical Science Award, 2003
Janssen Award for Clinical Research in Digestive Sciences, 2005
Previous Professional Positions and Appointments
Senior Associate Consultant, Division of Gastroenterology and Hepatology, Mayo Foundation, Rochester, MN, 19962001
Assistant Professor of Medicine, College of Medicine, Mayo Clinic, Rochester, MN 1997-2002
Associate Professor of Medicine, College of Medicine, Mayo Clinic, Rochester, MN 2002-2007
Professional Memberships and Societies
American Gastroenterological Association
American Motility Society
Functional Brain-Gut Group
Multinational Working Team (Rome Committee) to Develop Criteria for Functional Gastrointestinal Disorders
American College of Gastroenterology
Minnesota Medical Association
Zumbro Valley Medical Society
Institutional Committees
Research Committee, Division of Gastroenterology and Hepatology
Radiation Safety Committee
Research Plan Task Force, Division of Gastroenterology and Hepatology
Teaching/Examining Membership in the Mayo Graduate Faculty in Clinical Research
Multidisciplinary Training Grant in Digestive Diseases, member of Executive
Committee DK 07198
Fellows Educational Curriculum Task Force, Division of Gastroenterology and Hepatology
Study Coordinator Job Evaluation Subcommittee
Executive Committee, Kogod Program on Aging
Education Committee, Advanced Female Pelvic Medicine and Reconstructive Surgery Fellowship
Finance Committee, Division of Gastroenterology and Hepatology
CTSA Predoctoral Programs Committee
1998 - 2004
2000 - 2002
2000
2001 - present
2001 - 2005
2001
2002 - 2004
2003 - present
2003 - 2006
2007 – present
2009 - present
Extramural Committees
Member/Chair, Abstract Selection Committee, American Gastroenterological Association
Clinical Testing Task Force on Sensory Testing, American Motility Society
Award Selection Committee, Functional Brain-Gut Research Group
Co-Chair Subcommittee on Functional Disorders of the Anus and Rectum,
Multinational Working Team (Rome Committee) to Develop Criteria
for Functional Gastrointestinal Disorders
Committee on Practice Parameters, American College of Gastroenterology
Committee on Clinical Neurophysiological Testing, International Continence Initiative
Organizer and Co-Chair, Live Interactive Motility Testing Session, American Motility Society
Counselor, Functional Brain-Gut Research Group
Editorial Board, American Journal of Gastroenterology
Research Awards Committee, American Gastroenterological Association
Council Member, American Motility Society
Editorial Board, Neurogastroenterology and Motility
1999 1999 - 2000
2000 - 2002
2002 - 2004
2002 - 2006
2002 - 2004
2004
2004 – 2006
2005 - 2009
2007 –
2008 –
2009 -
Adil E. Bharucha, M.D.
Educational Activities
Teaching activities
Clinicopathological Conference
1990
A 39 year old man with fever, skin rash and weight
Gastroenterology Grand Rounds
1993
The Role of CEA Screening in Colon Cancer
Biliary Sludge and Acute Pancreatitis
Vascular Diseases Involving the Liver
1994
Constipation: From the Bedside to Motility Lab to the Bench
1995
Mallory-Weiss Syndrome: Back to the Basics
Fiber for IBS: Panacea or Placebo
Mechanism of Effects of Hyperventilation on Colonic Motor and Sensory
Function
1996
Visceral Hyperalgesia in IBS: Passing Fancy or Here to Stay
GERD and ENT Symptoms: Is There an Association?
Adrenergic Modulation of Colonic Motor and Sensory Function
1998
Paradigms for Assessing Human Colonic Motor Function In Vivo
2000
Anorectal Manifestations of Female Pelvic Floor Disorders
2006
Case presentations
2006
Laryngitis and GERD
2008
Understanding Urgency in Fecal Incontinence
2008
“Physiological testing in colorectal disorders – Interesting Case Presentations”
2009
Gastrointestinal Dysmotilides
Meetings of the Motility Interest Group/Enteric Neurosciences Program
2001
Statistical Issues for the Basic Scientist
2003-2005
Review of Important Abstracts – DDW 2004
2004
Epidemiology of Fecal Incontinence
2008
An Integrated Perspective of Gastric Motor Functions
2009
Do Patients with Rapid Gastric Emptying have Gastric Motor Dysfunctions and
Metabolic Syndrome?
Physical Medicine and Rehabilitation Resident Conference
1999
Bowel Function in the Elderly
Core Curriculum Conferences to Internal Medicine Residents/GI Fellows, 1993-date
Medical Grand Rounds
2001
Novel Approaches to Exploring Pathophysiology of Pelvic Floor
Dysfunction
Division of Colon and Rectal Surgery
2002-7
Fecal Incontinence (I): Pathophysiology
Fecal Incontinence (II): Therapeutic Approaches (Non-surgical)
Mayo-Sponsored Courses
1998
Geriatric Update for the Primary Care Physician: Bowel Function in the
Elderly
1999
Mayo Gastroenterology and Hepatology Course, Kohala HA: Management of
Gastroparesis and Pseudo-obstruction
2001
Mayo Gastroenterology and Hepatology Course, Kohala HA: Management of
Gastroparesis and Pseudo-obstruction
2001
Gastroenterology Board Review Course, Rochester, MN – Constipation and
Diverticulosis, Pelvic Floor Dysfunction
2002
Gastroenterology Board Review Course – Constipation and
Diverticulosis, Pelvic Floor Dysfunction
2003
GIH Postgraduate Course: Disorders of Pelvic Floor Function
Gastroenterology Board Review Course – Constipation and
Diverticular Diseases
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Adil E. Bharucha, M.D.
2003
2004
2005
2006
2007
2008
th
24 Annual Mayo Clinic Practice of Internal Medicine, Rochester, MN,
“Help for the Patient with Fecal Incontinence”
Gastroenterology Board Review Course, Chicago Il – Constipation and
Disorders of the Pelvic Floor
Advances in Gastroenterology and Hepatology Course, Minneapolis, MN –
“What’s New in Constipation?” and “Dyspepsia, IBS, Constipation and
Dysmotility”
Gastroenterology and Hepatology 2005, Kohala, HA, Pelvic Floor Dysfunction
Biology of Aging Symposium Course: The Aging Gut
Gastroenterology Board Review Course, Chicago, Il.– Constipation and
Disorders of the Pelvic Floor
Gastroenterology Board Review Course, Chicago, Il. – Constipation and
Disorders of the Pelvic Floor
Gastroenterology and Hepatology Board Review, Chicago, Il.—Constipation
and Disorders of the pelvic floor
Mayo Clinic Gastroenterology and Hepatology 2007, Grand Bahama Island,
Bahamas, Invited Speaker – “Evacuation disorders: What you need to
know”
Gastroenterology and Hepatology Board Review, Chicago Il —Constipation and
Disorders of the pelvic floor
3rd Annual Pain Medicine Symposium, Marco Island, Fl. – Chronic Abdominal
Pain
Mayo Clinic GI and Hepatology 2008, Lake Buena Vista, FL, Invited Speaker –
“Constipation: Dealing with the refractory patient”
Mentorship
Name
Dr.Ngai-Moh Law
Year
1996-1997
Current position
Faculty Member, University of Singapore
Dr. Anita Undale
1999
Post-doctoral fellow, Division of Endocrinology,
Mayo Clinic Rochester
Dr. Somchai Leelakusolvong
1997-1999
Assistant Professor of Medicine, Mahidol
Univ., Siriraj Hospital, Bangkok, Thailand
Dr. Jean Fox
2000-2001
Consultant, Division of Gastroenterology
and Hepatology, Mayo Clinic, Rochester
Dr. Christopher Klingele
2001-2002
Consultant, Division of Obstetrics & Gynecology
Mayo Clinic, Rochester
Dr. Andrew Croak
2002-2003
Urogynecologist, Northwest Ohio Center for
Urogynecology and Women’s Health,
Maumee, Ohio
Dr. Ebenezer Babalola
2003-2004
Faculty, Department of Gynecology, William
Beaumont Hospital, Royal Oak, Michigan
Dr. Suzanne Skoog
2003-2004
Gastroenterologist, Scottsdale, Arizona
Dr. Christopher Andrews
2004-2005
Assistant Professor, Division of
Gastroenterology, University of Calgary Faculty of
Medicine, Calgary, Alberta
Dr. Roberta Blandon
2005-2008
Faculty, Gynecology and Pelvic Reconstructive
Surgery, University of Missouri, Kansas City, Mo.
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Adil E. Bharucha, M.D.
Dr. Karthik Ravi
2008-
Fellow, Gastroenterology, Mayo Clinic, Rochester
Thesis Advisory Committee Membership
2002
2002
2004
2006
Silvia Delgado-Aros, M.D. (CLRSH 8/01)
Heather Chial, M.D
Filippo Cremonini, M.D
Viola Andresen, M.D.
Mentorship Committee
2001
2002
2004
2006
Heather Chial, M.D., NIH Fellow, Division of Gastroenterology and Hepatology
Shiva Kumar, M.D., Fellow, Division of Gastroenterology and Hepatology
Shamina Dhillon, M.D., Fellow, Division of Gastroenterology and Hepatology
Kevin Ruff, M.D., Fellow in Gastrointestinal Motility, Division of Gastroenterology and Hepatology
Reviewer for Journals, Books, Abstracts, and Publications
American Journal of Gastroenterology
American Journal of Physiology
Digestive Diseases and Sciences
Gastroenterology
Gut
Journal of Applied Physiology
Journal of Physiology, London
Mayo Clinic 50 Head-to-Toe Health Tips (MC1597)
Mayo Clinic Health Letter
Mayo Clinic HealthQuest
“Mayo Clinic on Chronic Pain”
Mayo Clinic Women’s Healthsource
Mayo Foundation Network Sites on Constipation and Fecal Incontinence
Neurogastroenterology and Motility
Section of Patient Education: Lower GI Motility Tests booklet
Digestive Disease Week, 2004, 2005, 2007, 2008
International Foundation for Functional Gastrointestinal Disorders, Member Editorial Board, 2008
Presentations and National and International Meetings
All presentations are indicated with an asterisk in the abstract section of bibliography.
Invited Presentations and Visiting Lectureships (non-Mayo sponsored courses)
1995
1996
January 1997
February 1998
February 1999
April 1999
May 1999
April 2000
April 2000
May 2000
Tulane University Medical Center, New Orleans, LA, Invited Lecturer – “Adrenergic
Modulation of Colonic Motor and Sensory Function”
University of North Carolina, Chapel Hill, NC, Invited Lecturer- “Adrenergic Modulation
of Colonic Motor and Sensory Function”
Falk Symposium: Intestinal Week in the Black Forest, Germany, Invited Lecturer –
“Psychosensory modulation of colonic sensation in IBS”
American College of Gastroenterology Regional Postgraduate Course, Minneapolis, MN,
Moderator and Speaker – “Update on Motility Disorders”
American Motility Society Postgraduate Course, Philadelphia, PA, Invited Lecturer “Constipation”
Consensus Conference on Fecal Incontinence, University of Wisconsin-Madison Medical
School, Milwaukee, WI, Invited Lecturer – “Fecal Incontinence in Geriatric Patients”
Digestive Disease Week, American Motility Society Discussion Panel, Orlando, FL,
Invited Participant – “Clinical Motility and Sensory Testing”
IFFGD Third International Symposium on Motility Disorders, Milwaukee, WI, Invited
Lecturer - “Fecal Incontinence in Geriatric Patients”
Midwestern Section of the American Federation for Medical Research, Chicago, IL,
Invited Lecturer – “The Aging Gut; Central Society for Clinical Research”
101st Annual Meeting of the American Gastroenterological Association, San Diego, CA,
Invited Lecturer – “MR for Constipation and Incontinence”
Adil E. Bharucha, M.D.
July 2000
April 2001
September 2002
November 2002
November 2002
November 2002
April 2003
May 2003
November 2003
January 2004
March 2004
May 2004
June 2004
July 2004
September 2004
October 2004
November 2004
November 2004
April 2005
May 2005
May 2005
June 2005
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Second International Consensus Meeting on Barostat Procedures, Toulouse, France,
Invited Participant – “How should colonic tone and compliance be measured?”
1st Asian Pacific Postgrad Course, Asian Medical Center, Seoul, Korea, Invited Lecturer
– “Assessment of Colonic Motor Function” and “Defecography”
9th Symposium on Neurogastroenterology and GI Motility, University of Iowa, Iowa City,
IA, Invited Speaker – “Assessment of Colonic Motility by Barostat-Manometric
Studies in Humans”
Ninth Symposium on Gastrointestinal Motility, Maui, Hawaii, Invited participant –
“Clinical Approach and Prokinetics for Constipation” and “Video Presentation of
Barostat”
Symposium on Advancing the Treatment of Fecal and Urinary Incontinence Through
Research: Trial Design, Outcome Measures, and Research Priorities” Milwaukee,
WI, co-sponsored by NIH, Course Faculty - “Physiological Outcome Measures for
Fecal Incontinence,
NIH Meeting on Basic Science and Translational Research in Female Pelvic Floor
Disorders, Bethesda, MD, Invited participant – “Understanding Anorectal
Manifestations of Female Pelvic Floor Disorder”
IFFGD 5th International Symposium on Functional Gastrointestinal Disorders,
Milwaukee, WI, Invited lecturer – “Anorectal Disorders and Symptoms”
Digestive Disease Week, Orlando, FL, Invited lecturer – “Anorectal Manifestations of
Pelvic Floor Dysfunction: Pathophysiology and Management”
44th Annual Indian Society of Gastroenterology Conference 2003, Madras, India, Invited
Faculty – “Constipation – Pathogenesis & management of pelvic floor
dysfunction”
American Motility Society Postgraduate Course, Nashville, TN, Course Faculty “Assessment of Colorectal Function”, “Colonic/Anorectal Physiology and
Pathophysiology”, and “Colonic/Anorectal Physiology and Pathophysiology”
UKT International Symposium, Urinary and Faecal Incontinence: An Interdisciplinary
Approach, Tubingen, Germany, Invited Lecturer – “Faecal incontinence not related
to surgery”
American Gastroenterological Association, Postgraduate Course, New Orleans, LA,
Course Faculty - “Current Concepts and Controversies in Functional GI Disorders”
3rd International Continence Initiative, Monaco, France, Invited Member - Committee on
Clinical Neurophysiological Testing
University of Texas Medical Branch at Galveston, TX, Invited Lecturer – “Small and
Large Intestine: Best of DDW” and “Physiology and Pathophysiology of Colonic
Motor Functions: Recent Insights”
American Motility Society Meeting, Rochester, MN, Invited Faculty and Lecturer –
“Colonic and Anorectal Cases” and “Live-Interactive Motility Testing –
Assessment of Colonic Motility by Barostat-Manometric Assembly”
Annual Update in Gastroenterology, Cedars Sinai Medical Center, Monterey, CA, Invited
Lecturer - “Pathophysiology and Management of Chronic Constipation”
National GI Meeting, Asociacion Mexicana de Gastroenterologia, Acapulco, Mexico,
Invited Lecturer – “Approach to the patient with functional constipation”, “The
future on GI functional disorders”, “Current concepts on Functional Dyspepsia”,
and “Ask the expert of the Mayo Clinic”
Rome III Meeting, Rome, Italy, Invited Participant – “Working Teams Chair/Co-Chair
Meeting”
IFFGD 6th International Symposium on Functional GI Disorders, Milwaukee, WI, Invited
Speaker – “Anorectal Disorders - Panel discussion”
American Gastroenterological Association Digestive Disease Week, Chicago, IL, Invited
Chair – “Functional GI Disorders: Symptoms, Diagnosis, Epidemiology and
Validation”
American Gastroenterological Association Postgraduate Course, Chicago, IL, Invited
Speaker - “Fecal Incontinence”
Mayo Clinic’s Robert and Arlene Kogod Program on Aging: Biology of Aging
Symposium, Rochester, MN, Invited Speaker – “The Aging Gut”
Adil E. Bharucha, M.D.
September 2005
September 2005
November 2005
November 2005
February 2006
February 2006
April 2006
May 2006
June 2006
September 2006
November 2006
April 2007
May 2007
July 2007
December 2007
December 2007
January 2008
April 2008
April 2008
May 2008
September 2008
November 2008
January 2009
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Symposium on Anorectal Disorders, University of Milan, Italy, Invited Speaker - “Fecal
incontinence: pathophysiology and treatment”
14th Meeting of the American Motility Society and Postgraduate Course, Santa Monica,
CA, Course Faculty – “Colonic Constipation: Physiology, Diagnosis, and
Management”
46th Annual Conference of Indian Society of Gastroenterology, Visakhapatnam, India,
Invited Faculty – “New Insights and Future Trends in Gastroenterology, Digestive
Endoscopy, and Liver Diseases”
Current and Emerging Therapies in Gastrointestinal Motility and Functional GI disorders,
Mass General Hospital, Boston, MA, Invited Speaker - “Constipation”
American Motility Society Course on Gastrointestinal Motility in Clinical Practice, San
Diego, CA, Invited Speaker – “Evaluation and Utility of Colorectal Function
Tests”, “Fecal Incontinence: Evaluation and Treatment”, “Breath Testing for GI
Disorders”, and “Meet the Professor: New Insights in Gut Motility”
University of California San Diego, San Diego, CA, Visiting Professor, GI Grand Rounds
- “Pathophysiology and Management of Fecal Incontinence”
Update in Gastroenterology, Mayo Clinic Course Chicago, IL, Invited Speaker “Constipation with pelvic floor dysfunction”
AGA Digestive Disease Week, Los Angeles, CA, Invited Speaker – “New insights in gut
motility”
Brown University Medical School, Providence, RI, GI Grand Rounds Invited Lecturer “Anorectal Manifestations of Pelvic Floor Disorders”
Neurogastroenterology and Motility 2006 Joint International Meeting, Boston, MA,
Invited Chair – “Novel Approaches to Diagnosis”
New in Motility and Endoscopy, University Hospital, Berne, Switzerland, Invited Speaker
- Controversies in Gastroenterology: “Disorder of defecation: there are several
diagnostic tests, but what are the therapeutic consequences?
IFFGD 7th International Symposium on Functional Gastrointestinal Disorders,
Milwaukee, WI, Invited Speaker – “Diagnostic approaches for anorectal
conditions.”
AGA Digestive Disease Week, Washington DC, Invited Speaker – “Controversies in
constipation ”
American Gastroenterological Association Meeting, Los Angeles, CA, Invited Speaker –
“Focused Clinical Update: Review of Abstracts- Anorectum and Pelvic Floor” and
“Constipation: Which diagnostic tests in which patients?”
Association of Gastrointestinal Motility Disorders Digestive Motility Symposium,
Burlington, MA, Invited Speaker - “What you need to know about fecal
incontinence and difficult defecation.”
NIH State-of-the-Science Conference; National Institutes of Health; Washington DC,
Invited Speaker - “Pathophysiology of Fecal Incontinence: Prevention of Fecal and
Urinary Incontinence in Adults”
Gastrointestinal Microbiota and Advances in Previotic and Probiotic Research; National
Institutes of Health; Washington DC, Invited Speaker - “Elderly and Gut
Microbiota”.
Invited Lecturer - January 2008
GI Grand Rounds University of North Carolina,
Chapel Hill, NC, Invited Speaker - “Perspectives on identifying phenotypes in
lower gastrointestinal disorder”
Functional Brain and Gut Retreat, Los Angeles, CA, Invited Participant – Future of FBG
2008 Update in Hepatology and Gastroenterology, Chicago, IL, Invited Speaker –
“Constipation, and how to get bowels to move again”
AGA Digestive Disease Week, San Diego, CA, Invited Speaker – “Fecal incontinence –
New perspectives on early detection, current and future therapies”
Texas Society for Gastroenterology and Endoscopy, Austin, TX, Invited Speaker –
“Anorectal Disorders”
International Motility Society Meeting, Lucerne Switzerland, Invited Speaker –
“Pathophysiology and Management of Fecal Incontinence”
AGA/American Motility Society/NIH Symposium on Gastroparesis and Functional
Adil E. Bharucha, M.D.
April 2009
May 2009
August 2009
8
Dyspepsia, Invited Speaker – “Novel Imaging Approaches”
IFFGD 7th International Symposium on Functional Gastrointestinal Disorders,
Milwaukee, WI
Invited Speaker – Symposium on “Epidemiology of Fecal incontinence”
Digestive Diseases Week, Chicago, IL, Invited Speaker –
“New Treatments of Functional GI and Motility Disorders”
“Management of Fecal Incontinence” (Meet the Professor)
“Advances in Diagnostic Evaluation of Pelvic Floor Disorders”
Neurogastroenterology and Motility Joint Meeting, Chicago, IL, Invited Speaker
“Noninvasive Assessment of Gastric Function and Emptying: From Scintigraphy to
MRI”
Research Grants Awarded
1.
2.
3.
4.
5.
6.
7.
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9.
10.
11.
12.
13.
Effects of a Serotonin 5-HT4 Receptor Antagonist on Gastrointestinal Sensori-motor Functions in Healthy Subjects:
SKB Pharmaceuticals
CR 10 Award, Mayo Foundation: Assessment of Colonic Pressure-Volume Relationships in Healthy Volunteers
(1/98-1/99)
Clinical Research Award, American College of Gastroenterology: A Pilot Study of Pyridostigmine for Constipation
in Patients With an Autonomic Neuropathy (4/98)
CR-20 Award, Mayo Foundation: A Pilot Study of Pyridostigmine for Constipation in Patients With an Autonomic
Neuropathy (1/99-12/99)
Clinical Research Award, American College of Gastroenterology: Biomechanical Properties of the Human Colon
(2000)
RO1 HD38666, NIH: PI. Anorectal Manifestations of Female Pelvic Floor Disorders (4/1/00-3/31/05)
RO1 HD41129, NIH: PI. Epidemiology and Mechanisms of Fecal Incontinence (9/1/01-7/31/06); NCE from
7/1/06- 6/31/08
DK 68055-NIH: PI. Neurohumoral Regulation in Diabetic Enteropathy (10/1/04-9/30/09)
Pfizer: PI. Comparison of Specific and Nonspecific Antagonists on Gastrointestinal Transit in Healthy Subjects
(2006)
Pfizer: PI. Effect of Tolterodine, a Nonspecific Muscarinic Antagonist on Gastrointestinal Transit in Healthy
Subjects: Pfizer Inc. (2006)
Novartis Inc: PI. Efficacy of Tegaserod for Constipation due to Spinal Cord Injury (2006)
RO1 DK78924, NIH: PI. Pathophysiology of Anorectal Disorders (4/1/08-1/31/12)
Pfizer: PI. A Randomized, Double Blind, Placebo Cotrolled, Parallel Group, Multiple Dose Study To Investigate
The Effects Of 8 Mg Fesoterodine Sr Tablet And 10 Mg Solifenacin Tablet On Gastrointestinal Transit In
Healthy Female Subjects. (2009-2010)
Grant Reviewer
AGA Research Awards
Health Research Board, Ireland
Veterans Administration Merit Review
Wellcome Trust, UK
Whitaker Foundation
National Institutes of Health – Digestive Sciences SBIR proposals – 2006, 2007, 2008, 2009.
National Institutes of Health – Special Emphasis Panel/Scientific Review Group 2008, 2009
Patent Applications
Systems Devices and Methods for Assessment of Body Cavity Pressures - filed 7/29/09
Imaging Gastrointestinal Volumes and Motility - filed 6/28/10
Adil E. Bharucha, M.D.
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BIBLIOGRAPHY
Peer Reviewed Articles
1.
Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS. Prevalence of stroke in the Parsi
Community of Bombay. Stroke 1988;19(1):60-2.
2.
Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS. Case-control study of completed ischemic
stroke in the Parsis of Bombay: a population based study. Neurology 1988;38(3):490-2.
3.
Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS. Prevalence of epilepsy in the Parsi
Community of Bombay. Epilepsia 1988;29(2):111-15.
4.
Bharucha NE, Bharucha EP, Wadia NH, Singhal BS, Bharucha AE, Bhise AV, Kurtzke JF, Schoenberg BS.
Prevalence of multiple sclerosis in the Parsis of Bombay. Neurology 1988;38(5):727-29.
5.
Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS. Prevalence of essential tremor in the Parsi
Community of Bombay, India. Arch Neurol 1988;45(8):907-8. Erratum in: Arch Neurol 1990;47(1):11
6.
Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS. Prevalence of Parkinson's disease in the
Parsi Community of Bombay, India. Arch Neurol 1988;45(12):1321-3.
7.
Bharucha NE, Bharucha AE, Bharucha EP. Prevalence of peripheral neuropathy in the Parsi Community of
Bombay. Neurology 1991;41(8):1315-17.
8.
Bharucha NE, Bharucha EP, Bharucha AE. Febrile Seizures. Neuroepidemiology 1991;10(3):138-42.
9.
Bharucha AE, Camilleri M, Low PA, Zinsmeister AR. Autonomic dysfunction in gastrointestinal motility
disorders. Gut 1993;34(3):397-401.
10. LeWitt PA, Bharucha AE, Chitrit I, Takis C, Patel S, Schork MA, Pichurko B. Perceived exertion and muscle
efficiency in Parkinson's disease: L-Dopa effects. Clin Neuropharmacol 1994;17(5):454-59.
11. Bharucha AE, Camilleri M, Ford MJ, O'Connor MK, Hanson RB, Thomforde GM. Hyperventilation alters colonic
motor and sensory function: effects and mechanisms in humans. Gastroenterology 1996;111(2):368-77.
12. Bharucha AE, Tremaine WJ, Johnson CD, Batts KP. Ischemic proctosigmoiditis. Am J Gastroenterol
1996;91(11):2305-9.
13. Bharucha AE, Gostout CJ, Balm RA. Clinical and endoscopic risk factors in the Mallory-Weiss syndrome. Am J
Gastroenterol 1997;92(5):805-8.
14. Bharucha AE, Camilleri M, Zinsmeister AR, Hanson RB. Adrenergic modulation of human colonic motor and
sensory function. Am J Physiol Gastrointest Liver Physiol 1997;273(5 Pt 1):G997-1006.
15. Bharucha AE, Novak V, Camilleri M, Zinsmeister AR, Hanson RB, Low PA. 2-adrenergic modulation of colonic
tone during hyperventilation. Am J Physiol Gastrointest Liver Physiol 1997;273(5 Pt 1):G1135-40.
16. Norby SM, Bharucha AE, Larson MV, Temesgen Z. Acute pancreatitis associated with Cryptosporidium parvum
enteritis in an immunocompetent man. Clin Infect Dis 1998;27(1):223-4.
17. Tremaine WJ, Bharucha AE. Ischemic proctitis with and without colonic involvement. Gastroenterology
International 1998; 11(2): 87-91.
18. Angulo P, Bharucha AE, Jorgensen RA, DeSotel CK, Sandborn WJ, LaRusso NF, Lindor KD. Oral nicotine in
treatment of primary sclerosing cholangitis: a pilot study. Dig Dis Sci 1999;44(3):602-7.
Adil E. Bharucha, M.D.
10
19. Busse RF, Riederer SJ, Fletcher JG, Bharucha AE, Brandt KR. Interactive fast spin-echo imaging. Magn Reson
Med 2000;44(3):339-48.
20. Bharucha AE, Camilleri M, Haydock S, Ferber I, Burton D, Tompson D, Fitzpatrick K, Higgins R, Zinsmeister
AR. Effects of a serotonin 5-HT4 receptor antagonist SB-207266 on gastrointestinal motor and sensory function in
humans. Gut 2000;47(5):667-74.
21. Bharucha AE, Jorgensen R, Lichtman SN, LaRusso NF, Lindor KD. A pilot study of pentoxifylline for the
treatment of primary sclerosing cholangitis. Am J Gastroenterol 2000;95(9):2338-42.
22. Coulie B, Camilleri M, Bharucha AE, Sandborn WJ, Burton D. Colonic motility in chronic ulcerative
proctosigmoiditis and the effects of nicotine on colonic motility in patients and healthy subjects. Aliment Pharmacol
Ther 2001;15(5):653-63.
23. Salvioli B, Bharucha AE, Rath-Harvey D, Pemberton JH, Phillips SF. Rectal compliance, capacity, and rectoanal
sensation in fecal incontinence. Am J Gastroenterol 2001;96(7):2158-68.
24. Bharucha AE, Hubmayr RD, Ferber IJ, Zinsmeister AR. Viscoelastic properties of the human colon. Am J Physiol
Gastrointest Liver Physiol 2001;281(2):G459-66.
25. Law N-M, Bharucha AE, Undale AS, Zinsmeister AR. Cholinergic stimulation enhances colonic motor activity,
transit, and sensation in humans. Am J Physiol Gastrointest Liver Physiol 2001;281(5):G1228-37.
26. Prall RT, Bannon MP, Bharucha AE. Meckel’s diverticulum causing intestinal obstruction. Am J Gastroenterol
2001;96(12):3426-7.
27. Leelakusolvong S, Sarr MG, Miller SM, Phillips SF, Bharucha AE. Role of extrinsic innervation in modulating
nitrergic transmission in the canine ileocolonic region. Am J Physiol Gastrointest Liver Physiol 2002;283(1):G230-9.
28. Law N-M, Bharucha AE, Zinsmeister AR. Rectal and colonic distention-elicit viscerovisceral reflexes in humans.
Am J Physiol Gastrointest Liver Physiol 2002;283(2):G384-9.
29. Chiba T, Bharucha AE, Thomforde GM, Kost LJ, Phillips SF. Model of rapid gastrointestinal transit in dogs:
effects of muscarinic antagonists and a nitric oxide synthase inhibitor. Neurogastroenterol Motil 2002;14(5):535-41.
30. Fletcher JG, Busse RF, Riederer SJ, Hough D, Gluecker T, Harper CM, Bharucha AE. Magnetic resonance
imaging of anatomic and dynamic defects of the pelvic floor in defecatory disorders. Am J Gastroenterol
2003;98(2):399-411.
31. Leelakusolvong S, Bharucha AE, Sarr MG, Hammond PI, Brimijoin S, Phillips SF. Effect of extrinsic denervation
on muscarinic neurotransmission in the canine ileocolonic region. Neurogastroenterol Motil 2003;15(2):173-86.
32. Singer W, Opfer-Gehrking TL, McPhee BR, Hilz MJ, Bharucha AE, Low PA. Acetylcholinesterase inhibition: a
novel approach in the treatment of neurogenic orthostatic hypotension. J Neurol Neurosurg Psychiatry
2003;74(9):1294-8.
33. Chiba T, Sarr MG, Kendrick ML, Meile T, Zyromski NJ, Tanaka M, Kost LJ, Bharucha AE, Phillips SF:
Limitations of implantable, miniature ultrasonic transducers measure wall movement in the canine jejunum.J
Surg Res 2004;116(2):219-226.
34. Bharucha AE, Seide BM, Fox JC, Zinsmeister AR. Day-to-day reproducibility of anorectal sensorimotor
assessments in healthy subjects. Neurogastroenterol Motil 2004;16(2):241-50.
35. Bharucha AE, Locke G. Richard, Seide BM, Zinsmeister AR. A new questionnaire for constipation and faecal
incontinence. Aliment Pharmacol Ther 2004;20(3):355-64.
Adil E. Bharucha, M.D.
11
36. Bharucha AE, Dhamija S, Japp A, Seide B, Walters B, Stroetz R, Zinsmeister AR, Hubmayr RD. Contractile
response to colonic distention is influenced by oscillation frequency. Neurogastroenterol Motil 2005;17(1):64-75.
37. Bharucha AE, Fletcher JG, Harper CM, Hough D, Daube JR, Stevens C, Seide B, Riederer SJ, Zinsmeister AR.
Relationship between symptoms and disordered continence mechanisms in women with idiopathic fecal
incontinence. Gut 2005;54(4):546-55.
38. Bharucha AE, Fletcher JG, Seide B, Riederer SJ, Zinsmeister AR. Phenotypic variation in functional disorders of
defecation. Gastroenterology 2005;128(5):1199-210.
39. Bharucha AE, Zinsmeister AR, Locke GR, Seide BM, McKeon K, Schleck CD, Melton III LJ. Prevalence and
burden of fecal incontinence: a population-based study in women. Gastroenterology 2005;129(1):42-9.
40. Klingele CJ, Bharucha AE, Fletcher JG, Gebhart JG, Croak A, Riederer SG, Zinsmeister AR. Pelvic organ
prolapse in defecatory disorders. Obstet Gynecol 2005;106(2):315-20.
41. Bharucha AE, Locke GR, Zinsmeister AR, Seide BM, McKeon K, Schleck CD, Melton LJ III. Differences
between painless and painful constipation among community women. Am J Gastroenterol 2006;101(3):604-12.
42. Skoog, SM, Bharucha AE, Camilleri M, Burton D, Zinsmeister AR. Effects of an osmotically active agent on
colonic transit. Neurogastroenterol Motil 2006;18(4):300-6.
43. Camilleri M, Bharucha AE, Ueno R, Burton D, Thomforde GM, Baxter K, McKinzie S, Zinsmeister AR. Effect of
a selective chloride channel activator, lubiprostone, on gastrointestinal transit, gastric sensory and motor functions
in humans. Am J Physiol Gastrointest Liver Physiol 2006;290(5):G942-7.
44. Bharucha AE, Croak AJ, Gebhart JB, Berglund LJ, Seide BM, Zinsmeister AR, An Kai-Nan. Comparison of
rectoanal axial forces in health and functional defecatory disorders. Am J Physiol Gastrointest Liver Physiol
2006;290(6):G1164-69.
45. Bharucha, AE. Zinsmeister, AR. Locke, GR. Seide, BM. McKeon, K. Schleck, CD. Melton, LJ. Risk factors
for fecal incontinence: A population-based study in women. Am J Gastroenterol 2006; 101(6):1305-12.
46. Bharucha AE, Zinsmeister AR, Locke GR, Schleck CD, McKeon K, Melton LJ III. Symptoms and quality of life
in community women with fecal incontinence. Clin Gastroenterol Hepatol 2006;4(8):1004-9.
47. Gonenne J, Esfandyari T, Camilleri M, Burton DD, Stephens DA, Baxter KL, Zinsmeister AR, Bharucha AE.
Effect of female sex hormone supplementation and withdrawal on gastrointestinal and colonic transit in
postmenopausal women. Neurogastroenterol Motil 2006;18(10):911-8.
48. Fox JC, Fletcher JG, Zinsmeister AR, Seide B, Riederer SJ, Bharucha AE. Effect of aging on anorectal and pelvic
floor functions in females. Dis Colon Rectum 2006;49(11):1726-35; Erratumin in: Dis Colon Rectum 2007;
50(3):404.
49. Haider CR, Manduca A, Camp JJ, Fletcher JG, Robb RA, Bharucha AE. Geometric modeling, functional
parameter calculation, and visualization of the In-Vivo distended rectal wall. Proc. Of SPIE 2006;6143:D1-D11.
50. Andrews C, Bharucha AE, Seide B, Zinsmeister AR. Rectal sensorimotor dysfunctions in fecal incontinence. Am
J Physiol Gastrointest Liver Physiol 2007;292(1):G282-9.
51. Camilleri M, Andrews CN, Bharucha AE, Carlson PJ, Ferber I, Stephens D, Smyrk TC, Urrutia R, Aerssens J,
Thielemans L, Göhlmann H, Van Den Wyngaert I, Coulie B. Alterations in expression of p11 and SERT in mucosal
biopsy specimens of patients with irritable bowel syndrome. Gastroenterology 2007;132(1):17-25.
52. Andrews CN, Bharucha AE, Camilleri M, Low PA, Seide B, Burton D, Baxter K, Zinsmeister AR. Nitrergic
contribution to gastric relaxation induced by glucagon-like peptide-1 (GLP-1) in healthy adults. Am J Physiol
Gastrointest Liver Physiol 2007; 292(5):G1359-65.
Adil E. Bharucha, M.D.
12
53. Babalola EO, Bharucha AE, Schleck CD, Gebhart JB, Zinsmeister AR, Melton LJ. Decreasing utilization of
hysterectomy: a population-based study in Olmsted County, Minnesota, 1965-2002. Am J Obstet Gyncol 2007;
196(3):214.e1-7. NIHMSID: 65843
54. Melton JL III, Achenback SJ, Gebhart JB, Babalola EO, Atkinson EJ, Bharucha AE. Influence of hysterectomy on
long-term fracture risk. Fertil Steril 2007; 88(1):156-62. PMCID: PMC2032011
55. Andrews CN, Bharucha AE, Camilleri M, Low PA, Seide BM, Burton DD, Nickander KK, Baxter KL,
Zinsmeister AR. Effects of glucagon-like peptide-1 and sympathetic stimulation on gastric accommodation in
humans. Neurogastroenterol Motil 2007; 19(9):716-23. NIHMSID: 65845
56. Blandon RE, Bharucha AE, Melton LJ 3rd, Schleck CD, Babalola EO, Zinsmeister AR, Gebhart JB. Incidence of
pelvic floor repair after hysterectomy: A population-based cohort study. Am J Obstet Gynecol 2007;
197(6):664.e1-7. NIHMSID: 65846
57. Aerssens J, Camilleri M, Talloen W, Thielemans L, Gohlmann HW, Van Den Qyngaert I, Thielemans T, De Hoogt
R, Andrews CN, Bharucha AE, Carlson PJ, Busciglio I, Burton DD, Smyrk T, Urrutia R, Coulie B. Alterations in
mucosal immunity identified in the colon of patients with irritable bowel syndrome. Clin Gastroenterol Hepatol
2008; 6(2):194-205.
58. Bharucha AE, Seide B, Zinsmeister AR, Melton LJ III. Insights into normal and disordered bowel habits from
bowel diaries. Am J Gastroenterol 2008; 103(3):692-8. NIHMSID: 65848
59. Skoog SM, Bharucha AE, Zinsmeister AR. Comparison of breath testing with fructose and high fructose corn
syrups in health and IBS. Neurogastroenterol Motil 2008; 20(5):505-11. NIHMSID: 65849
60. Bharucha AE, Seide BM, Guan Z, Andrews CN, Zinsmeister AR. Effect of tolterodine on gastrointestinal
transit and bowel habits in healthy subjects. Neurogastroenterol Motil 2008; 20(6):643-8.
61. Bharucha AE, Skaar R, Andrews CN, Camilleri M, Philips S, Seide B, Burton D, Baxter K, Zinsmeister AR.
Relationship of Cytochrome P450 pharmacogenetics to the effects of Yohimbine on gastrointestinal transit and
catecholamines in healthy subjects. Neurogastro Motil 2008; 20: 891-899. NIHMSID: 65850
62. Bharucha AE, Seide B, Zinsmeister AR, Melton JL. Relation of bowel habits to fecal incontinence in women. Am
J Gastroenterol 2008;103(6):1470-5. NIHMSID: 65852
63. Bharucha AE, Low PA, Camilleri M, Burton D, Gehrking TL, Zinsmeister AR. Pilot study of pyridostigmine in
constipated patients with autonomic neuropathy. Clinical Autonomic Research 2008;18(4):194-202. NIHMSID:
65854
64. Bharucha AE, Charkoudian N, Andrews CN, Camilleri M, Sletten D, Zinsmeister AR, Low PA. Effects of
glucagon-like peptide-1 (GLP-1), Yohimbine, and Nitrergic modulation on sympathetic and parasympathetic
activity in humans. Am J of Physiol, Reg Integ Physiol. 2008;295(3):R874-80.
65. Babalola EO, Bharucha AE, Melton LJ 3rd, Schleck CD, Zinsmeister AR, Klingele CJ, Gebhart JB. Utilization of
surgical procedures for pelvic organ prolapse: a population-based study in Olmsted County, Minnesota, 1965-2002.
International Urogynecology Journal. 2008;19(9):1243-50.
66. Camilleri M, Bharucha AE, di Lorenzo C, Hasler WL, Prather CM, Rao SS, Wald A. American
Neurogastroenterology and Motility Society consensus statement on intraluminal measurement of
gastrointestinal and colonic motility in clinical practice. Neurogastroenterol Motil 2008; 20(12):1269-82.
67. Bharucha AE, Camilleri M, Forstrom L, Zinsmeister AR. Relationship between clinical features and gastric
emptying disturbances in diabetes mellitus. Clin Endocrinol (Oxf). 70(3):415-20, 2009 Mar.
Adil E. Bharucha, M.D.
13
68. Fidler JL, Bharucha AE, Camilleri M, Camp J, Burton D, Grimm R, Riederer SJ, Robb R, and Zinsmeister AR.
Application of Magnetic Resonance Imaging to Measure Fasting and Postprandial Volumes in Humans.
Neurogastroenterol Motil 2009;21(1):42-51.
69. Blandon RE, Bharucha AE, Melton LJ 3rd, Schleck CD, Babalola EO, Zinsmeister AR, Gebhart JB. Risk Factors
for Pelvic Floor Repair After Hysterectomy. Obstet Gynecol. 2009;113(3):601-8.
70. Sweetser S, Busciglio IA, Camilleri M, Bharucha AE, Szarka LA, Papathanasopoulos A, Burton DD, Eckert
DJ, Zinsmeister AR. Effect of a Chloride Channel Activator, Lubiprostone, on Colonic Sensory and Motor
Functions in Healthy Subjects. Am J Physiol Gastrointest Liver Physiol. 296(2):G295-301, 2009 Feb.
71. Savica R, Grossardt BR, Carlin JM, Bower JH, Ahlskog JE, Maraganore DM, Bharucha AE, Rocca WA.
Reduced bowel movements preceding Parkinson’s disease: a case-control study. Neurology 2009;73(21):17528.
72. Odunsi ST, Camilleri M, Bharucha AE, Papathanasopoulos A, Busciglio I, Burton D, Zinsmeister AR.
Reproducibility and Performance Characteristics of Colonic Compliance, Tone, and Sensory Tests in Healthy
Humans. Dig Dis Sci 2010;55(3):709-715.
73. Ravi K, Bharucha AE, Camilleri M, Rhoten D, Bakken, T, Zinsmeister A. Phenotypic Variation of Colonic
Motor Functions in Chronic Constipation. Gastroenterology 2010; 138(1):89-97
74. Bharucha AE, Kulkarni A, Moo Choi K, Camilleri M, Lempke M, Brunn GJ, Gibbons S, Zinsmeister AR,
Farrugia G. First-In-Human Study Demonstrating Pharmacological Activation of Heme Oxygenase-1 in
Humans. Clin Pharmacol Ther 2010;87(2):187-190.
75. Parkman HP, Camilleri M, Farrugia G, McCallum RW, Bharucha AE, Mayer EA, Tack JF, Spiller R, Horowitz
M, Vinik AI, Galligan JJ, Pasricha PJ, Kuo B, Szarka LA, Marciani L, Jones K, Parrish CR, Sandroni P, Abell
T, Ordog T, Hasler W, Koch KL, Sanders K, Norton NJ, Hamilton F. Gastroparesis and functional dyspepsia:
excerpts from the AGA/ANMS meeting. Neurogastroenterol Motil 2010 Feb; 22(2):113-33.
76. Deiteren A, Camilleri M, Bharucha AE, Burton D, McKinzie S, Rao AS, Zinsmeister AR. Performance
characteristics of scintigraphic colon transit measurement in health and irritable bowel syndrome and
relationship to bowel functions. Neurogastroenterol Motil 2010;22(4):415-23, e95.
77. Bharucha AE, Wald AM. Anorectal disorders. American Journal of Gastroenterology 2010; 105(4):786-94.
78. Bharucha AE, Ravi K, Zinsmeister AR. Effects of selective M3 and non-selective muscarinic receptor
antagonists on gastrointestinal transit and bowel habits in humans. American Journal of Physiology 2010; In
press.
79. Klingele CJ, Lightner DJ, Fletcher JG, Gebhart JB, Bharucha AE. Dysfunctional urinary voiding in women
with functional defecatory disorders. Neurogastroenterol Motil 2010 In press. NIHMSID: 214407.
80. Bharucha AE, Seide BM, Zinsmeister AR. Effect of clonidine on symptoms and anorectal sensorimotor
function in women with fecal incontinence. Alimentary Pharmacology and Therapeutics 2010 In press.
NIHMSID: 214323.
81. Bharucha AE, Zinsmeister AR, Schleck CD, Melton LJ 3rd. Bowel disturbances are the main risk factors for late
onset fecal incontinence: A population-based case-control study in women. Gastroenterology In press.
Book Chapters
1.
Bharucha AE and Lindor KD. Primary biliary cirrhosis, primary sclerosing cholangitis and other miscellaneous
cholangiopathies. In: Stein JH, ed. Internal Medicine. St Louis: Mosby; 1998:2199-2203.
Adil E. Bharucha, M.D.
14
2.
Bharucha AE and Camilleri M. Physiology of the colon. In: Zuidema GD, Yeo CJ, eds. Shackelford’s Surgery of
the Alimentary Tract: The Colon. 5th ed. Vol. IV. Philadelphia: W.B. Saunders Co.; 2002:29-39.
3.
Bharucha AE, Camilleri M. Gastrointestinal dysmotility and sphincter dysfunction. In: Noseworthy JH, ed.
Neurological Therapeutics: Principles and Practice. Vol. II. London: Martin Dunitz; 2003:2255-2266.
4.
Bharucha AE, Camilleri M. Common large intestinal disorders. In: Hazzard WR, et al. eds Principles of geriatric
medicine and gerontology. 5th ed. New York: McGraw-Hill Professional; 2003:641-653.
5.
Bharucha AE. Disorders of pelvic floor function. In: Hauser SC, ed. Mayo Clinic Gastroenterology and
Hepatology Board Review. Rochester: Mayo Clinic Scientific Press; 2004:231-5.
6.
Bharucha AE. Constipation. In: Hauser SC, ed. Mayo Clinic Gastroenterology and Hepatology Board Review.
Rochester: Mayo Clinic Scientific Press; 2004:223-9.
7.
Camilleri M, Bharucha AE. Overview of gastrointestinal dysfunction in diseases of central and peripheral nervous
system. In: Quigley EMM, Pfeiffer RF, eds. Neurogastroenterology-Gastrointestinal Dysfunction in Neurological
Disease. New York: Cambridge University Press; 2004:35-57.
8.
Bharucha AE. Anorectal Disorders. In: Spiller R, Grundy D, eds. Pathophysiology of the Enteric Nervous System:
A Basis for Understanding Functional Diseases. Oxford: Blackwell Publishing; 2004:161-175.
9.
Bharucha AE, Klingele CJ. Autonomic and somatic systems to the anorectum and pelvic floor. In: Dyck PJ,
Thomas PK, eds. Peripheral Neuropathy. 4th ed. Vol. 2. Philadelphia: Elsevier Saunders.; 2005:279-98.
10. Bharucha AE, Camilleri M. Management of gut dysmotility. In: Dyck PJ, Thomas PK, eds. Peripheral
Neuropathy. 4th ed. Vol. 2. Philadelphia: Elsevier Saunders; 2005:2683-706.
11. Vodusek DB, Amarenco G, Batra A, Benson T, Bharucha AE, Podnar S, Yang CC. Clinical Neurophysiology. In:
Abrams P, Cardozo L, Khoury S, Wein A, eds. Incontinence. Vol. 1. Paris: Health Publication, Ltd.; 2005:675-706.
12. Bharucha, AE. Wald, A. Enck, P. Rao, S. Functional anorectal disorders. Gastroenterology 2006; 130(5):15108. (Review)
13. Bharucha AE. Constipation and disorders of pelvic floor function. In: Hauser SC, ed. Mayo Clinic
Gastroenterology and Hepatology Board Review. 2d ed. Rochester: Mayo Clinic Scientific Press; 2006: 233-44.
14. Bharucha AE. Treatment of fecal incontinence. In: Wolfe MM et al, ed. Therapy of Digestive Disorders 2d ed.
Philadelphia: Elsevier Saunders; 2006:1031-6.
15. Bharucha AE, Fletcher JG, Pemberton JF. Dynamic MRI and nuclear imaging. In: Wexner SD, Duthie GS, ed.
Constipation: etiology, Evaluation and Management. 2d ed. London: Springer; 2006:111-6.
16. Bharucha AE, Camilleri M. Gastrointestinal dysmotility and sphincter dysfunction. In: Noseworthy JH, ed.
Neurological Therapeutics: Principles and Practice. 2d ed. Abingdon: Informa Healthcare; 2006:2552-65.
17. Bharucha AE. Functional Anorectal Disorders. In: Drossman DA, ed. Rome III: The Functional Gastrointestinal
Disorders, 3d ed. McLean: Degnon Associates, Inc; 2006: 639-687.
18. Bharucha AE, Camilleri M. Physiology of the colon and its measurement. In: Pemberton JH, ed. Shackelford’s
Surgery of the Alimentary Tract. 6th ed. Vol. 4. The Colon, Philadelphia: Elsevier Saunders; 2007:1871-82.
19. Bharucha AE. Fecal incontinence. In: Talley NJ. Locke GR III. Saito YA, editors. GI Epidemiology. Malden:
Blackwell. 2007: 207-14.
20. Bharucha AE, Blandon RE. Anatomy and Physiology of Continence. In: Fecal Incontinence: Diagnosis and
Treatment. Ratto C and Doglietto GB, Eds. 2007:3-12.
Adil E. Bharucha, M.D.
15
21. Bharucha AE, Wald A. Anorectal diseases. In: Textbook of Gastroenterology, 5th ed . Yamada T, ed. Lippincott
Williams and Wilkins. 2008: 1717-44.
22. Camilleri M, Bharucha AE. Disturbances of gastrointestinal motility and the nervous system. In: Aminoff M, ed.
Neurology and General Medicine. 4th ed. Philadelphia: Elsevier, Inc. 2008: 293-310.
23. Bharucha AE, Wald A. Anorectal diseases. In: Atlas of Gastroenterology. 5th ed. Yamada T, ed. Oxford:
Lippincott Williams and Wilkins. 2008: 491-507.
24. Bharucha AE. Investigation of Fecal Incontinence. In: Imaging and Pelvic Floor Disorders 2nd ed. Taylor S, ed.
Heidelberg: Springer-Verlag. 2008: 229-244.
25. Fletcher JG, Bharucha AE, Siddiki S. Dynamic MR Imaging of the Pelvic Floor. In: Imaging Pelvic Floor
Disorders. Stoker J, Taylor S, DeLancey JOL, eds. Springer, 2008: 75-88.
26. Bharucha AE. Constipation and disorders of pelvic floor function In: Hauser SC. Pardi DS. Poterucha JJ, editor(s).
Mayo Clinic gastroenterology and hepatology board review 3rd edition. Rochester: Mayo Clinic Scientific Press;
2008. 257-70.
27. Bharucha AE. Irritable Bowel Syndrome. In: The Merck of Medical Information- Home Edition. 3rd Ed. Merck
Research Laboratories. In Press.
28. Bharucha AE. Irritable Bowel Syndrome. In: The Merck Manual of Diagnosis. 19th Ed. Merck Research
Laboratories. In Press.
29. Bharucha AE. Constipation in Adults. In: The Merck Manual of Patient Symptoms. Merck Research Laboratories.
In Press.
30. Bharucha AE. Diarrhea in Adults. In: The Merck Manual of Patient Symptoms. Merck Research Laboratories. In
Press.
31. Bharucha AE. Gas. In: The Merck Manual of Patient Symptoms. Merck Research Laboratories. In Press.
32. Ravi, K, Bharucha, AE. Anorectal testing. In: Talley N, Kane S, Wallace M, ed. Practical Gastroenterology
and Hepatology, Vol 2, Small and Large Intestine and Pancreas. _______: Wiley Blackwell; 2010: In Press.
33. Ravi, K, Bharucha, AE. Fecal Incontinence. In: Talley N, Kane S, Wallace M, ed. Practical Gastroenterology
and Hepatology, Vol 2, Small and Large Intestine and Pancreas. _______: Wiley Blackwell; 2010: In Press.
Editorials and Review Articles
1.
Camilleri M, Bharucha AE. Gastrointestinal dysfunction in neurologic disease. Semin Neurol 1996; 16(3):203-16.
(Review)
2.
Camilleri M, Saslow SB, Bharucha AE. Gastrointestinal Sensation: Mechanisms and relation to functional GI
disorders. Gastroenterol Clin North Am 1996; 25(1):247-58. (Review)
3.
Bharucha AE. Obstructed defecation - Don’t strain in vain! [Editorial] Am J Gastroenterol 1998;93(7):1019-20.
4.
Bharucha AE, Phillips SF. Colon and Anorectum: Megacolon: acute, toxic, and chronic. Cur Treat Opt
Gastroenterol 1999;2(6):517-23.
5.
Camilleri M, Lee JS, Viramontes B, Bharucha AE, Tangalos EG. Insights into the pathophysiology and
mechanisms of constipation, irritable bowel syndrome, and diverticulosis in older people. J Am Geriatr Soc
2000;48(9):1142-50. (Review)
6.
Bharucha AE, Phillips SF. Slow transit constipation. Gastroenterol Clin North Am 2001;30(1):77-95. (Review)
Adil E. Bharucha, M.D.
16
7.
Bharucha AE, Camilleri M. Functional abdominal pain in the elderly. In: Camilleri M, ed. Gastroenterol Clin
North Am 2001;30(2):517-529. (Review)
8.
Bharucha AE. Gastrointestinal motility: tests and problem-oriented approach. Gastroenterology
2001;120(4):1056-1058. (Review)
9.
Bharucha AE. Fecal Incontinence. Gastroenterology 2003;124(6):1672-85. (Review)
10. Bharucha AE. Innervation of the gastrointestinal tract. Gastroenterology 2003;125(6):1907-1908. (Review)
11. Skoog SM, Bharucha AE. Dietary fructose and gastrointestinal symptoms: a review. Am J Gastroenterol
2004;99(10):2046-50. (Review)
12. Bharucha AE. Treatment of severe and intractable constipation. Curr Treat Option Gastroenterol
2004;7(4):291-298; Rev Gastroenterol Mex 2004; 69 Suppl 3:89-94.
13. Bharucha AE. Outcome measures for fecal incontinence: anorectal structure and function. Gastroenterology
2004;126(1 Suppl 1):S90-S98. (Review)
14. Andrews, CN. Bharucha, AE. Review: good evidence supports polyethylene glycol and tegaserod for constipation.
ACP J Club 2005;143(2):47. (Review)
15. Andrews, CN. Bharucha, AE. The etiology, assessment, and treatment of fecal incontinence. Nat Clin Pract
Gastroenterol Hepatol 2005;2(11):516-25. (Review)
16. Bharucha AE. Update of tests of colon and rectal structure and function. J Clin Gastroenterol 2006; 40(2):96-103.
(Review)
17. Bharucha AE. Pelvic floor anatomy and function. Neurogastroenterol Motil 2006;18(7):507-19. (Review)
18. Bharucha AE. Dissecting esophageal sensori-motor functions: the fourth domain. [Editorial] Neurogastroenterol
Motil 2006;18(3):169-71.
19. Camilleri M, Bharucha AE. Drawing a blank in functional dyspepsia? [Editorial] Gastroenterology
2006;130(2):593-6.
20. Bharucha AE. Anorectal manometry and imaging are necessary in patients with fecal incontinence. [Editorial]
Am J Gastroenterol 2006;101(12):2679-81.
21. Bharucha AE. Pro: Anorectal testing is useful in fecal incontinence. Am J Gastroenterol 2006; 101(2): 2679-81.
(Debate)
22. Bharucha AE. Severe gastrointestinal motor disorders. Constipation. Best Pract Res Clin Gastroenterol 2007;
21(4):709-31.
23. Bharucha AE, Fletcher JG. Recent advances in assessing anorectal structure and functions. Gastroenterology
2007; 113:1069-74.
24. Bharucha AE. Functional and Chronic Anorectal and Pelvic Pain Disorders. In Gastroenterology Clinic of North
America. Elsevier.com. 2008: 687-696.
25. Bharucha AE. Lower Gastrointestinal Functions. Neurogastroenterol Motil 2008; 20 Suppl 1:103-13.
26. Bharucha AE. Methylnaltrexone reduced opioid-induced constipation in patients with terminal illness. Evidence
Based Medicine 2008; (in print). (Review)
Adil E. Bharucha, M.D.
17
27. Bharucha AE. Management of fecal incontinence. Gastroenterology and Hepatology 2008; 4(11):
28. Bharucha, AE. Review: PPI use in pregnancy was not associated with increased congenital malformations,
spontaneous abortion, or preterm delivery. ACP Journal Club. 2009; 151(5)JC5-14.
29. Samsom M, Bharucha AE, Gerich JE, Herrmann K, Limmer J, Linke R, Maggs D, Schirra J, Vella A, Worle HJ,
Goke B. Diabetes mellitus and gastric emptying: questions and issues in clinical practice. Diabetes/Metabolism
Research Reviews. 2009; 25(6):502-14. (Review)
30. Bharucha AE, Waldman SA. Taking a Lesson From Microbial Diarrheagenesis in the Management of Chronic
Constipation. Gastroenterology 2010 Jan 26. [Epub ahead of print]
31. Bharucha AE, Linden DR. Linaclotide - a secretagogue and antihyperalgesic agent - what next?
Neurogastroenterol Motil 2010 Mar; 22(3):227-31.
32. Whitehead WE, Bharucha AE. Diagnosis and Treatment of Pelvic Floor Disorders: What's New and What to
Do. Gastroenterology 2010; 138, (4): 1231-1235.
33. Bharucha AE. Incontinence: An underappreciated problem in obesity and bariatric surgery. Digestive Diseases
and Sciences 2010; In press.
Articles in Non-Peer Reviewed Publications
1.
Bharucha AE. How should muscle tone and compliance be measured? In: Syllabus for Consensus Meeting on
Barostat Procedures, July 1-2, 2000, Hotel Dieu St Jacques, Toulouse, France.
2.
Bharucha AE. Fecal incontinence. In: Internal Medicine Newsletter, Mayo Clinic, Vol. 23, No. 3, February
2001:13-17.
3.
Bharucha AE. Fiber Sources. Mayo Clinic Health Letter 2003;21(10). (Review)
4.
Bharucha AE. Summary of Clinical Research Activities – Incontinence. In: International Foundation for
Functional Gastrointestinal Disorders Newsletter, Digestive Health Matters, Vol. 13, No. 3, Fall 2004:14-15.
5.
Bharucha, AE. Pathophysiology of chronic constipation and IBS...includes discussion. Advanced Studies in
Medicine 2006 Feb;6(2A):S58-66, S101-3.
Adil E. Bharucha, M.D.
18
Abstracts
1.
Bharucha AE, Low PA, Zinsmeister AR, Camilleri M. Autonomic dysfunction in patients with neurological
disorders and idiopathic gastrointestinal motility disorders. [Abstract] Gastroenterology 1992;102:A425.
2.
Bharucha AE, Chitrit I, Patel S, Takis C, Pichurko B, LeWitt PA. Exercise physiology in Parkinson's disease:
fatigue and efficiency studies. [Abstract] Neurology 1992;42(Suppl 3):P309.
3.
Bharucha AE, Gostout CJ, Balm RK. Acute gastrointestinal bleeding due to a Mallory Weiss tear. [Abstract]
Gastrointestinal Endoscopy 1994;40(Suppl):72.
4.
Bharucha AE, Camilleri M, Low PA, Hanson RB, Thomforde GM, Ford MJ, Klee GC, O'Connor MK.
Mechanism of hyperventilation-induced changes in colonic tone in man. [Abstract] Gastroenterology
1995;108(Suppl):A570.
5.
Bharucha AE, Camilleri M, Zinsmeister A, Hanson RB. Adrenergic effects on sensation in the human colon:
evidence in favor of central 2 modulation. [Abstract] Gastroenterology 1995;110(4 Suppl):A633.
6.
Bharucha AE, Camilleri M, Zinsmeister A, Hanson RB. Adrenergic modulation of human colonic motor function:
potential therapeutic indications. [Abstract] Gastroenterology 1995;110(4 Suppl):A633.
7.
Bharucha AE, Camilleri M, Zinsmeister A, Hanson RB. 2-adrenergic modulation of human colonic compliance
analyzed by an exponential function. [Abstract a16] Dig Dis Sci 1996;41(9):1883.
8.
Bharucha AE, Novak V, Camilleri M, Hanson RB, Zinsmeister AR, Low PA. Power spectral analysis of
autonomic effects of hyperventilation in humans. [Abstract] Clinical Autonomic Research1996; 6:304.
9.
Bharucha AE, Camilleri M, Novak V, Zinsmeister AR Low PA. 2-adrenergic modulation of colonic tone during
hyperventilation. [Abstract] Gastroenterology 1997;112(4 Suppl):A699.
10. Bharucha AE, Camilleri M, Zinsmeister AR, Ford MJ. Psychosensory modulation of colonic sensation in IBS.
[Abstract] Gastroenterology 1997;112(4 Suppl):A699.
11. Bharucha AE, Jorgensen RA, Gores GJ, LaRusso NF, Plevy S, Lindor KD. A pilot study evaluating pentoxifylline
in the treatment of primary sclerosing cholangitis. [Abstract] Hepatology 1997;26(4 Part 2):402A.
12. Angulo P, Bharucha AE, Jorgensen RA, Sandborn WJ, LaRusso NF, Lindor KD. Oral nicotine in the treatment of
primary sclerosing cholangitis: A pilot study. [Abstract] Gastroenterology 1998;114(4 Part 2):A1204.
13. Lichtman SN, Bharucha AE, Jorgensen RA, Lindor KD. Evidence that the bacterial cell wall polymer
peptidoglycan-polysaccharide (PG-PS) plays a role in primary sclerosing cholangitis. [Abstract] Gastroenterology
1998;114(4 Part 2):A1290.
14. Law N-M, Bharucha AE, Camilleri M. Colonic motor function in chronic megacolon. [Abstract]
Neurogastroenterol Motil 1998;10:A92.
15. Bharucha AE, Ferber I, Camilleri M. Developing a modified noninvasive scintigraphic test to evaluate proximal
colonic transit in humans. [Abstract] Neurogastroenterol Motil 1998;10:A11.
16. Law N-M, Bharucha AE, Zinsmeister AR. Comparison of neostigmine and bethanechol effects on colonic motor
activity, compliance and sensation in healthy volunteers. [Abstract] Gastroenterology 1998;114:A3232.
17. Law N-M, Bharucha AE. Phasic rectal distention induces colonic relaxation in humans. [Abstract]
Gastroenterology 1998;114:A3232.
Adil E. Bharucha, M.D.
19
18. Coulie B, Camilleri M, Bharucha AE, Sandborn WJ, Tremaine WJ. Acute effects of nicotine on motor function
and compliance of the human descending colon. [Abstract] Dig Dis Sci 1998;43:1588.
19. Bharucha AE, Hubmayr RD, Ferber I, Zinsmeister AR. Colonic pressure-volume relationships in humans:
reproducibility and demonstration of hysteresis. [Abstract] Gastroenterology 1999;116(4 Part 2):A958.
20. Bharucha AE, Camilleri M, Ferber I, Zinsmeister AR. Effects of a serotonin (5-HT4) receptor antagonist on
gastrointestinal (GI) transit, colonic motor, and sensory function in health. [Abstract] Gastroenterology 1999; 116(4
Part 2):A958.
21. Coulie B, Bharucha AE, Burton D, Sandborn WJ, Camilleri M. Nicotine accelerates transit in the human colon:
exploring the motor actions and mediators. [Abstract] Gastroenterology 1999;116(4 Part 2):A978-9.
22. Leelakusolvong S, Bharucha AE, Sarr MG, Phillips SF. Muscarinic M1 receptor modulation of colonic motor
activity in intact and denervated canine colon. [Abstract] Gastroenterology 1999;116(4 Part 2):A1064.
23. Coulie B, Camilleri M, Bharucha AE, Sandborn WJ. A mechanistic study of colonic motor changes in chronic
ulcerative colitis and effects of nicotine. [Abstract] Neurogastreoenterol Motil 1999;11:P255.
24. Leelakusolvong S, Bharucha AE, Tanaka T, Sarr MG, Phillips SF. Effect of extrinsic denervation on nitrergic
neurotransmission in the canine colon. [Abstract] Neurogastroenterol Motil 1999;11:P272.
25. Leelakusolvong S, Bharucha AE, Sarr MG, Phillips SF. Effects of extrinsic denervation and nitrergic
neurotransmission on the canine ileocolonic junction. [Abstract] Neurogastroenterol Motil 1999;11:P272.
26. Bharucha AE, Hubmayr RD, Ferber I. Cholinergic modulation of human colonic pressure-volume relationships.
[Abstract] Gastroenterology 2000;118(4 Suppl 2 Part 1):AGA833.
27. Chiba T, Bharucha AE, Thomforde GM, Kost LJ, Phillips SF. Model of rapid gastrointestinal transit in dogs:
effects of muscarinic antagonists and a nitric oxide synthase inhibitor. [Abstract] Gastroenterology 2000;118(4
Supple Part 2):AGA1165.
28. Chiba T, Sarr MG, Bharucha AE, Kendrick ML, Tanaka T, Zyromski NJ, Phillips SF. Implantable ultrasonic
transducers measure canine jejunal wall motion in vivo. [Abstract] Gastroenterology 2000;118(4 Suppl 2 Part
1):A152.
29. Fox JC, Bharucha AE, Zinsmeister AR, Rhoten DL, Kammer PL. Diagnostic utility of colonic compliance
assessment in constipated patients. [Abstract] Gastroenterology 2001;120(5 Suppl 1):A753.
30. Bharucha AE, Law N-M, Undale AH, Ferber IA. Neostigmine but not bethanechol accelerates colonic transit in
healthy subjects. Neurogastroenterol Motil 2001;13(4):375.
31. Klingele CJ, Fletcher JG, Riederer SJ, Gebhart JB, Helwig PS, Zinsmeister AR, Bharucha AE. MR proctography:
a novel approach for imaging pelvic floor motion. [Abstract] Gastroenterology 2002;122 (Suppl):A449.
32. Fox JC, Rath-Harvey DM, Helwig PS, Zinsmeister AR, Bharucha AE. Anal sphincter pressures and rectal
compliance decline with aging in asymptomatic women. [Abstract] Gastroenterology 2002;122(Suppl):A69.
33. Fletcher JG, Klingele CJ, Gebhart JB, Helwig P, Riederer SJ, Bharucha AE. MR proctography for identifying
pelvic floor dysfunction in obstructed defecation. [Abstract] Gastroenterology 2002;122(Suppl):A447.
34. Bharucha AE, Hubmayr RD, Walters BJ, Stroetz RW. Novel approach to characterize impedance and
mechanotransduction in the human colon. [Abstract] Gastroenterology 2002;122(Suppl):A320.
35. Ramage JI Jr, Bharucha AE, Baron TH Sr. Percutaenous endoscope cecostomy for recurrent Olgilvie’s syndrome.
[Abstract 531] American J of Gastroenterology 2002;97:S175.
Adil E. Bharucha, M.D.
20
36. Fajardo N, Rhoten DL, Kammer PP, Reeves RK, Christopherson MW, Bharucha AE. Colonic motility after
supraconal chronic spinal cord injury. [Abstract] Gastroenterology 2003;124(4):A569.
37. Seide B, Fox JC, Croak AJ, Zinsmeister AR, Bharucha AE. Reproducibility of anorectal function tests. [Abstract]
Gastroenterology 2003;124(4):A685.
38. Japp A, Dhamija S, Bharucha AE, Walters BJ, Stroetz RW, Hubmayr RD, Zinsmeister AR. Colonic
mechanotransduction in humans is influenced by oscillation frequency. [Abstract] Gastroenterology
2003;124(4):A570.
39. Fletcher JG, Harper CM, Stevens JC, Daube JR, Christensen JA, Riederer SJ, Bharucha AE. Puborectalis
dysfunction in fecal incontinence. [Abstract] Gastroenterology 2003;124(4):A115.
40. Fajardo NR, Bharucha AE, Rhoten DL, Kammer PP, Zinsmeister AR. Colonic motor dysfunction in pelvic floor
dysfunction. [Abstract] Neurogastroenterol Motil 2003;15(2):211.
41. Cremonini F, Camilleri M, Bharucha AE. Balloon expulsion test in chronic constipation: performance versus
defecography and manometry. [Abstract 6] Neurogastroenterol Motil 2003;15(2):210.
42. Oxentenko AS, Alexander GI, Bharucha AE. Hodgkin’s lymphoma presenting with hearing loss, paresthesias,
and intestinal pseudo-obstuction. [Abstract] Am J Gastroenterol 2003;98(9Suppl):5158-59.
43. Fajardo NR, Croak AJ, Seide BM, Berglund LJ, An K-N, Gebhart JB, Zinsmeister AR, Bharucha AE. Recto-anal
forces during squeeze, expulsion and valsalva maneuver. [Abstract] Gastroenterology 2004;126(4):A86.
44. Seide B, Locke GR III, Schleck C, Zinsmeister A, Bharucha AE. A new questionnaire for fecal incontinence
and constipation (FICA). [Abstract] Gastroenterology 2004;126(4):A365.
45. Skoog S, Simonson J, Arora A, Diehl N, Harmsen WS, Locke GR III, Longstreth G, Romero Y, Thistle J,
Zinsmeister A, Bharucha AE. Post-cholecystectomy diarrhea: a prospective study of incidence. [Abstract]
Gastroenterology 2004;126(4):A370.
46. Bharucha AE, Locke GR, McKeon K, Seide B, Schhleck C, Zinsmeister AR, Melton LJ III. Prevalence and
Impact of Fecal Incontinence in Women. [Abstract] Gastroenterology 2004;126(4):A378.
47. Klingele CJ, Lightner DJ, Gebhart JB, Bharucha AE. Prevalence of voiding dysfunction in patients with
obstructed defecation. [Abstract 28] J Pelvic Med Surg 2004;10(Suppl 1):S11-2.
48. Bharucha AE, Locke GR, McKeon K, Seide BM, Schleck C, Zinsmeister A, Joseph L. Multiple risk factos for
fecal incontinence in a community. [Abstract 42] Neurogastroenterol Motil 2004; 16(5):660.
49. Skoog SM, Bharucha AE, Camilleri M, Burton D, Seide B, Zinsmeister AR. Assessment of ascending colonic
volume by SPECT scintigraphy in humans. [Abstract] Gastroenterology 2005;128:A276.
50. Seide BM, Berglund LJ, An K-N, Zinsmeister AR, Bharucha AE. Day-to-day reproducibility of recto-anal
forces during squeeze, expulsion, and valsalva maneuver. [Abstract] Gastroenterology 2005;128:A269.
51. Bharucha AE, Locke GR III, McKeon K, Seide B, Schleck C, Zinsmeister AR, Melton LJ III. Differences
between painless versus painful constipation. [Abstract] Gastroenterology 2005;128:A264.
52. Andrews CN, Seide BM, Zinsmeister AR, Bharucha AE. Effect of distention rate on rectal sensory thresholds
in health and fecal incontinence. [Abstract] Gastroenterology 2005;128:A264.
53. Andrews CN, Bharucha AE, Camilleri M, Burton D, Baxter K, Seide BM, Zinsmeister AR. Glucagon-like
peptide (GLP-1) and gastric volume – effects and mechanisms. [Abstract 43] Neurogastroenterol Motil
2005;17(4):615.
Adil E. Bharucha, M.D.
21
54. Camilleri M, Bharucha AE, Panas RM, Gargano M, Perentesis G, Burton D, Thomforde GM, Baxter K,
Mckinzie S, Zinsmeister AR. Effect of a chloride channel activator, lubiprostone, on gastrointestinal transit, gastric
sensory, and motor functions in humans. [Abstract 88] Neurogastroenterol Motil 2005;17(4):629.
55. Daube J, Traue J, Litchy W, Mowzoon N, Bharucha AE. Anal sphincter motor unit potential (MUP)
differences between sides, and between rest and voluntary contraction in normal subjects [Abstract P06.109].
Neurology 2006;66(5 Suppl 2):A358-9.
56. Traue J, Daube JR, Litchy WJ, Mowzoon N, Enck P, Bharucha AE. Validation of a novel surface EMG probe
for assessing anal sphincter innervation. [Abstract] Gastroenterology 2006;130:A727.
57. Seide BM, Klingele CJ, Gebhart JB, Zinsmeister AR, Bharucha AE. Effect of hysterectomy on anorectal
functions - a prospective study. [Abstract] Gastroenterology 2006;130:A727.
58. Andrews CN, Bharucha AE, Camilleri M, Seide BM, Baxter KM, Burton DB, Zinsmeister AR. Effect of
yohimbine on gastrointestinal transit and symptoms in healthy subjects. [Abstract] Gastroenterology
2006;130:A290.
59. Andrews CN, Seide BM, Zinsmeister AR, Bharucha AE. Comparison of rectal contractile responses during
inflation, sustained distention, and deflation in health and fecal incontinence. [Abstract] Gastroenterology
2006;130:A728.
60. Bharucha AE, Andrews C, Seide BM, Baxter K, Guan Z, Zinsmeister AR. Effect of a non-specific muscarinic
antagonist, tolterodine, on gastrointestinal and colonic transit in humans: a randomized, controlled study.
[Abstract 76] Neurogastroenterol Motil 2006;18(8):689.
61. Andrews CN, Camilleri M, Bharucha AE, Carlson PJ, Ferber IA, Stephens DA, Aerssens J, Thielemans L,
Gohlmann H, Van Den Wyngaert I, Boulie B. Alterations in expression of p11 (S100A 10) in mucosal biopsies
of patients with irritable bowel syndrome. [Abstract 73] Neurogastroenterol Motil 2006;18(8):688.
62. Babalola EO, Bharucha AE, Zinsmeister AR, Melton LJ III, Gebhart JB. Epidemiology of hysterectomy in
Olmsted County, MN, 1965-2002: a population-based study. [Abstract 73] J Pelvic Med Surg 2006;12(2):113.
63. Bharucha AE, Camilleri M, Forstrom L, Stapleton RF, Zinsmeister AR. Predicting abnormal gastric emptying in
diabetes mellitus. [Abstract] Neurogastroenterol Motil 2007;19(5):423.
64. Bharucha AE, Fidler J, Camilleri M, Camp J, Stapleton R, Burton D, Robb R, Riederer SJ. Comparison of gastric
volumes measured by MRI and SPECT. [Abstract] Neurogastroenterol Motil 2007; May 19(5): 421-2.
65. Aerssens J, Camilleri, Talloen W, Thielemans L, Gohlmann H, Van den wyngaert I, Thielemans T, Andrews CN,
Bharucha AE, Carlson P, Busciglio I, Burton D, Smyrk T, Urrutia R, Coulie B. Molecular signatures for altered
muscosal immunity in colon in irritable bowel syndrome. [Abstract S2166} Gastroenterology 2007; 132(4):A331.
66. Skoog S, Bharucha AE, Zinsmeister AR. Comparison of breath testing with fructose and high fructose corn syrups
in health and IBS. [Abstract M1113] Gastroenterology 2007; 132(4):A364.
67. Bharucha AE, Seide B, Zinsmeister AR. A prospective assessment of anorectal functions and symptoms one
year after a simple hysterectomy. [Abstract T1947] Gastroenterology 2007; 132(4); A589.
68. Seide B, Bharucha AE, Zinsmeister, Melton JL. Comparison of bowel habits characterized by bowel diaries
versus questionnaires in health and fecal incontinence. [Abstract W1194] Gastroenterology 2007; 132(4):A680.
69. Bharucha AE, Seide B, Zinsmeister, Melton JL. Which factors predispose to incontinent bowel movements in
women with fecal incontinence. [Abstract 111]. Gastroenterology 2007; 132(4);A21.
70. Ravi K, Bharucha AE, Camilleri M, Rhoten D, Zinsmeister. Relationship between colonic motor functions and
transit in constipation. [Abstract] Gastroenterology 2008; 134(4);A677.
Adil E. Bharucha, M.D.
22
71. Bharucha AE, Fidler JL, Camp J, Camilleri M, Robb R, Riederer S, Zinsmeister AR. Comparison of Gastric
Volumes and Emptying in Functional Dyspepsia. [Abstract] Gastroenterology 2009; 136 (Suppl 1):W2064.
72. Ravi K, Rath-Harvey D, Zinsmeister AR, Bharucha AE. Do Rectoanal Pressures Predict Rectal Balloon
Expulsion in Chronic Constipation? [Abstract] Gastroenterology 2009;136:A101.
73. Bharucha AE, Seide B, Zinsmeister AR. Effect of clonidine on symptoms and anorectal functions in fecal
incontinence (FI) – a pilot study. [Abstract 92] Neurogastroenterology Motility 2009; Suppl 21:32.
74. Ravi K, Rath Harvey D, Seide B, Kulkarni A, Bharucha AE. Fecal incontinence (FI) is underrecognized in
clinical practice. [Abstract 120] Neurogastroenterol Motil 2009; Suppl 21:40.
75. Eaton J, Thapa P, Zinsmeister A, Choung RS, Bharucha A, Locke G. The incidence rate of clinically diagnosed
dyssynergic defecation in the community. Am J Gastroenterol 2009 Oct; 104(Suppl 3):1305.
76. Bharucha AE, Fletcher JG, Melton LJ, Zinsmeister AR. Pelvic Floor Injury and Dysfunctions in Fecal
Incontinence (FI): A Population-Based Case-Control Study. Gastroenterology 2010; 138 (5): S-30
77. Bharucha AE, Manduca A, Fidler JL, Lake D, Edwards P, Robb RA, Grimm R, Zinsmeister AR, Riederer SJ.
Gastric Motor Disturbances in Functional Dyspepsia with Rapid Gastric Emptying. Gastroenterology
2010; 138 (5): S-458.
78. Bharucha AE, Melton LJ, Schleck C, Zinsmeister AR. A Population-Based Case-Control Study of Fecal
Incontinence (FI). Gastroenterology 2010; 138(5): S-99.