Publications Susin’s Team (2007-2014)
2014
AlQahtani A, Touitou V, Cassoux N, Aknin C, Merle-Beral H, Bodaghi B, LeHoang P. More than a masquerade syndrome:
atypical presentations of vitreoretinal lymphomas. Ocul Immunol Inflamm, 22(3):189-96.
Baliakas P, Iskas M, Gardiner A, Davis Z, Plevova K, Nguyen-Khac F, Malcikova J, Anagnostopoulos A, Glide S, Mould S,
Stepanovska K, Brejcha M, Belessi C, Davi F, Pospisilova S, Athanasiadou A, Stamatopoulos K, Oscier D. Chromosomal
translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic
data. Am J Hematol, 89(3):249-55.
Chapiro E, Antony-Debre I, Marchay N, Parizot C, Lesty C, Cung HA, Mathis S, Grelier A, Maloum K, Choquet S, Azgui Z,
Uzunov M, Leblond V, Merle-Beral H, Sutton L, Davi F, Nguyen-Khac F. Sex chromosome loss may reprent a diseaseassociated clonal population in chronic lymphocytic leukemia. Genes Chromosomes Cancer, 53(3):240-7.
Cosson A, Chapiro E, Belhouachi N, Cung HA, Keren B, Damm F, Algrin C, Lefebvre C, Fert-Ferrer S, Luquet I, Gachard N,
Mugneret F, Terre C, Collonge-Rame MA, Michaux L, Rafdord-Weiss I, Talmant P, Veronese L, Nadal N, Struski S, Barin C,
Helias C, Lafage M, Lippert E, Auger N, Eclache V, Roos-Weil D, Leblond V, Settegrana C, Maloum K, Davi F, Merle-Beral H,
Lesty C, Nguyen-Khac F; on behalf of the Groupe Francophone de Cytogénétique Hématologique. 14q deletions are
associated with trisomy 12, NOTCH1 mutations and unmutated IGHV genes in chronic lymphocytic leukemia and small
lymphocytic lymphoma. Genes Chromosomes Cancer, 53(8):657-66.
Damm F, Mylonas E, Cosson A, Yoshida K, Della Valle V, Mouly E, Diop M, Scourzic L, Shiraishi Y, Chiba K, Tanaka H, Miyano
S, Kikushige Y, Davi F, Lambert J, Gautheret D, Merle-Beral H, Sutton L, Dessen P, Solary E, Akashi K, Vainchenker W,
Mercher T, Droin N, Ogawa S, Nguyen-Khac F, Bernard OA. Acquired initiating mutations in early hematopoietic cells of CLL
patients. Cancer Discov, 4(9):1088-101.
Ferreira P, Villanueva R, Martinez-Julve M, Herguedas B, Marcuello C, Fernandez-Silva P, Cabon L, Hermoso JA, Lostao A,
Susin SA, and Medina M. Structural insights into the coenzyme mediated monomer-dimer transition of the pro-apoptotic
Apoptosis Inducing Factor. Biochemistry, 53(25):4204-15.
Gentien D, Kosmider O, Nguyen-Khac F, Albaud B, Rapinat A, Dumont AG, Damm F, Popova T, Marais R, Fontenay M,
Roman-Roman S, Bernard OA, Stern MH. A common alternative splicing signature is associated with SF3B1 mutations in
malignancies from different cell lineages. Leukemia, 28(6):1355-7.
Gendron N, Belhouachi N, Morel V, Azgui Z, Maloum K, Nguyen-Khac F, Cayuela JM, Davi F, Merle-Béral H, Chapiro E.
Chronic myeloid leukemia with variant e19a2 BCR-ABL1 fusion transcript: interest of the molecular identification at
diagnosis for minimal residual disease follow-up. Ann Biol Clin (Paris), 72(3):359-366.
Grelier A, Le Garff-Tavernier M, Nauwelaers F, Sarfati M, Merle-Beral H. Soluble CD23 measurement by CBA: a convenient
and reliable quantification method in chronic lymphocytic leukemia. Cytometry B Clin Cytom, 86(2):91-7.
Harrison CJ, Rowley JD, Van den Berghe H, Bernheim A, Martineau M, Gautier M, Le Coniat-Busson M, Romana S, Dastugue
N, Hagemeijer A, Jonveaux P, Nguyen-Khac F, Bernard OA. No chromosome arm unturned: in memory of Roland Berger
1934-2012. Leukemia, 28(2):464-9.
Le Garff-Tavernier M, Herbi L, de Romeuf C, Nguyen-Khac F, Davi F, Grelier A, Boudjoghra M, Maloum K, Choquet S, Urbain
R, Vieillard V, Merle-Béral H. Antibody-dependent cellular cytotoxicity of the optimized anti-CD20 monoclonal antibody
ublituximab on chronic lymphocytic leukemia cells with 17p deletion. Leukemia, 28(1):230-3.
1
Mahendra A, Gangadharan B, André S, Boudjoghra M, Davi F, Lecerf M, Planchais C, Kaveri SV, Lacroix-Desmazes S,
Dimitrov JD. Cryptic polyreactivity of IgG expressed by splenic marginal zone B-cell lymphoma. Mol Immunol, 60(1):54-61.
Nguyen-Khac F, Valle VD, Lopez RG, Ghysdael J, Bernard OA. Deregulation of AhR function by the human acute leukemia
TEL-ARNT fusion protein. Am J Hematol, 89(5):566-7.
Rosenquist R, Davi F, Ghia P. The microenvironment in lmphomas – Dissecting the complex crosstalk between tumor cells
and ‘by-stander’ cells. Semin Cancer Biol, 24:1-2.
Saleh R, Wedeh G, Herrmann H, Bibi S, Cerny-Reiterer S, Sadovnik I, Blatt K, Hadzijusufovic E, Jeanningros S, Blanc C,
Legarff-Tavernier M, Chapiro E, Nguyen-Khac F, Subra F, Bonnemye P, Dubreuil P, Desplat V, Merle-Béral H, Willmann M,
Rülicke T, Valent P, Arock M. A new human mast cell line expressing a functional IgE receptor converts to factorindependence and tumorigenicity by KIT D816V-transfection. Blood, 124(1):111-20.
Te Raa GD, Malčiková J, Mraz M, Trbusek M, Le Garff-Tavernier M, Merle-Béral H, Greil R, Merkel O, Pospíšilová S, Lin K,
Pettitt AR, Stankovic T, van Oers MH, Eldering E, Stilgenbauer S, Zenz T, Kater AP; European Research Initiative on CLL
(ERIC). Assessment of TP53 functionality in chronic lymphocytic leukaemia by different assays; an ERIC-wide approach. Br J
Haematol. 2014 Jun 30. doi: 10.1111/bjh.13006.
Touitou V, Bodaghi B, Thepot S, Chapiro E, Nguyen-Khac F, Charlotte F, LeHoang P, Maloum K. When the eye gives it all:
diagnosis of relapsing acute myeloblastic leukemia with anterior chamber tap of a chronic hypopyon. Am J Hematol.,
89(8):858-9.
2013
Baliakas P, Iskas M, Gardiner A, Davis Z, Plevova K, Nguyen-Khac F, Malcikova J, Anagnostopoulos A, Glide S, Mould S,
Stepanovska K, Brejcha M, Belessi C, Davi F, Pospisilova S, Athanasiadou A, Stamatopoulos K, Oscier D. Chromosomal
translocations and karyotype complexity in cll: A systematic reappraisal of classic cytogenetic data. Am J Hematol.,
89(3):249-55.
Cabon L, Martinez-Torres AC, and Susin SA. La mort cellulaire programmée ne manque pas de vocabulaire. Médecine et
Sciences. 29:1117-24.
Couronné L, Scourzic L, Pilati C, Della Valle V, Duffourd Y, Solary E, Vainchenker W, Merlio JP, Beylot-Barry M, Damm F,
Stern MH, Gaulard P, Lamant L, Delabesse E, Merle-Beral H, Nguyen-Khac F, Fontenay M, Tilly H, Bastard C, Zucman-Rossi J,
Bernard OA, Mercher T. STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a
mouse bone marrow transplantation model. Haematologica. 98(11):1748-52.
Chapiro E, Radford-Weiss I, Cung HA, Dastugue N, Nadal N, Taviaux S, Barin C, Struski S, Talmant P, Vandenberghe P,
Mozziconacci MJ, Tigaud I, Lefebvre C, Penther D, Bastard C, Lippert E, Mugneret F, Romana S, Bernard OA, Harrison CJ,
Russell LJ, Nguyen-Khac F; Groupe Francophone de Cytogénétique Hématologique. Chromosomal translocations involving
the IGH@ locus in B-cell precursor acute lymphoblastic leukemia: 29 new cases and a review of the literature. Cancer
Genet. 206(5):162-73.
Ferreira P, Villanueva R, Cabon L, Susín SA, Medina M. The oxido-reductase activity of the apoptosis inducing factor: a
promising pharmacological tool? Curr Pharm Des. 19(14):2628-36.
Fisson S, Ouakrim H, Touitou V, Baudet S, Ben Abdelwahed R, Donnou S, Miloudi A, Galand C, Bodaghi B, Lehoang P,
Brissard M, Le Garff-Tavernier M, Fridman WH, Sautès-Fridman C, Cassoux N, Merle-Béral H. Cytokine profile in human
eyes: contribution of a new cytokine combination for differential diagnosis between intraocular lymphoma or uveitis. PLoS
ONE. 8(2):e52385.
2
Guy J, Antony-Debré I, Benayoun E, Arnoux I, Fossat C, Le Garff-Tavernier M, Raimbault A, Imbert M, Maynadié M,
Lacombe F, Béné MC, Wagner-Ballon O; GEIL (Groupe d'Etude Immunologique des Leucémies). Flow cytometry thresholds
of myeloperoxidase detection to discriminate between acute lymphoblastic or myeloblastic leukaemia. Br J Haematol.
161(4):551-5.
Leblond V, Johnson S, Chevret S, Copplestone A, Rule S, Tournilhac O, Seymour JF, Patmore RD, Wright D, Morel P, Dilhuydy
MS, Willoughby S, Dartigeas C, Malphettes M, Royer B, Ewings M, Pratt G, Lejeune J, Nguyen-Khac F, Choquet S, Owen RG.
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström
macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma. J Clin Oncol. 31(3):301-7.
Neven B, Mamessier E, Bruneau J, Kaltenbach S, Kotlarz D, Suarez F, Masliah-Planchon J, Billot K, Canioni D, Frange P,
Radford-Weiss I, Asnafi V, Murugan D, Bole C, Nitschke P, Goulet O, Casanova JL, Blanche S, Picard C, Hermine O, RieuxLaucat F, Brousse N, Davi F, Baud V, Klein C, Nadel B, Ruemmele F, Fischer A. A Mendelian predisposition to B-cell
lymphoma caused by IL-10R deficiency. Blood. 122(23):3713-22.
Nguyen-Khac F, Lambert J, Chapiro E, Grelier A, Mould S, Barin C, Daudignon A, Gachard N, Struski S, Henry C, Penther D,
Mossafa H, Andrieux J, Eclache V, Bilhou-Nabera C, Luquet I, Terre C, Baranger L, Mugneret F, Chiesa J, Mozziconacci MJ,
Callet-Bauchu E, Veronese L, Blons H, Owen R, Lejeune J, Chevret S, Merle-Beral H, Leblondon V; Groupe Français d'Etude
de la Leucémie Lymphoïde Chronique et Maladie de Waldenström (GFCLL/MW); Groupe Ouest-Est d’étude des Leucémie
Aiguës et Autres Maladies du Sang (GOELAMS); Groupe d’Etude des Lymphomes de l’Adulte (GELA). Chromosomal
aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia.
Haematologica. 98(4):649-54.
Rosenquist R, Davi F, Stamatopoulos K. Antigens in lymphoma development-Current knowledge and future directions.
Semin Cancer Biol. 23(6):397-8.
Strefford JC, Sutton LA, Baliakas P, Agathangelidis A, Malčíková J, Plevova K, Scarfó L, Davis Z, Stalika E, Cortese D, Cahill N,
Pedersen LB, di Celle PF, Tzenou T, Geisler C, Panagiotidis P, Langerak AW, Chiorazzi N, Pospisilova S, Oscier D, Davi F,
Belessi C, Mansouri L, Ghia P, Stamatopoulos K, Rosenquist R. Distinct patterns of novel gene mutations in poor-prognostic
stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2. Leukemia. 27(11):2196-9.
Sutton LA, Agathangelidis A, Belessi C, Darzentas N, Davi F, Ghia P, Rosenquist R, Stamatopoulos K. Antigen selection in Bcell lymphomas-Tracing the evidence. Semin Cancer Biol. 23(6):399-409.
Te Raa GD, Malcikova J, Pospisilova S, Trbusek M, Mraz M, Le Garff-Tavernier M, Merle-Béral H, Lin K, Pettitt AR, Merkel O,
Stankovic T, van Oers MH, Eldering E, Stilgenbauer S, Zenz T, Kater AP; European Research Initiative on CLL (ERIC). Overview
of available p53 function tests in relation to TP53 and ATM gene alterations and chemoresistance in chronic lymphocytic
leukemia. Leuk Lymphoma. 54(8):1849-53.
Véronèse L, Tournilhac O, Callanan M, Prie N, Kwiatkowski F, Combes P, Chauvet M, Davi F, Gouas L, Verrelle P, Guièze R,
Vago P, Bay JO, Tchirkov A. Telomeres and chromosomal instability in chronic lymphocytic leukemia. Leukemia. 27(2):4903.
2012
Agathangelidis A, Darzentas N, Hadzidimitriou A, Brochet X, Murray F, Yan XJ, Davis Z, van Gastel-Mol EJ, Tresoldi C, Chu CC,
Cahill N, Giudicelli V, Tichy B, Pedersen LB, Foroni L, Bonello L, Janus A, Smedby K, Anagnostopoulos A, Merle-Beral H,
Laoutaris N, Juliusson G, di Celle PF, Pospisilova S, Jurlander J, Geisler C, Tsaftaris A, Lefranc MP, Langerak AW, Oscier DG,
Chiorazzi N, Belessi C, Davi F, Rosenquist R, Ghia P, Stamatopoulos K. Stereotyped B-cell receptors in one third of chronic
lymphocytic leukemia: towards a molecular classification with implications for targeted therapeutic interventions.
Blood. 119(19):4467-75.
3
Baritaud M, Cabon L, Delavallée L, Galan-Malo P, Gilles M-E, Brunelle-Navas MN, and Susin SA. AIF-mediated caspaseindependent necroptosis requires ATM and DNA-PK-induced Ser139 histone H2AX phosphorylation. Cell Death & Disease,
3:e390.
Cabon L, Galan-Malo P, Bouharrour A, Delavallée L, Brunelle-Navas MN, Lorenzo HK, Gross A, and Susin SA. BID regulates
AIF-mediated caspase-independent necroptosis by promoting BAX activation. Cell Death & Differentiation. 19(2):245-56.
Dagklis A, Ponzoni M, Govi S, Cangi MG, Pasini E, Charlotte F, Vino A, Doglioni C, Davi F, Lossos IS, Ntountas I, Papadaki T,
Dolcetti R, Ferreri AJ, Stamatopoulos K, Ghia P. Immunoglobulin gene repertoire in ocular adnexal lymphomas: hints on the
nature of the antigenic stimulation. Leukemia. 26(4):814-21.
Damm F, Nguyen-Khac F, Fontenay M, Bernard OA. Spliceosome and other novel mutations in chronic lymphocytic
leukemia, and myeloid malignancies. Leukemia. 26(9):2027-31.
Damm F, Nguyen-Khac F, Kosmider O, Fontenay M, Bernard OA. [Mutations in genes involved in splicing in human
malignancies]. Med Sci (Paris). 28(5):449-53.
Langerak AW, Groenen PJ, Brüggemann M, Beldjord K, Bellan C, Bonello L, Boone E, Carter GI, Catherwood M, Davi F,
Delfau-Larue MH, Diss T, Evans PA, Gameiro P, Garcia Sanz R, Gonzalez D, Grand D, Håkansson A, Hummel M, Liu H,
Lombardia L, Macintyre EA, Milner BJ, Montes-Moreno S, Schuuring E, Spaargaren M, Hodges E, van Dongen JJ.
EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected
lymphoproliferations. Leukemia. 26(10):2159-71.
Leblond V, Johnson S, Chevret S, Copplestone A, Rule S, Tournilhac O, Seymour JF, Patmore RD, Wright D, Morel P, Dilhuydy
MS, Willoughby S, Dartigeas C, Malphettes M, Royer B, Ewings M, Pratt G, Lejeune J, Nguyen-Khac F, Choquet S, Owen RG.
Results of a Randomized Trial of Chlorambucil Versus Fludarabine for Patients With Untreated Waldenstrom
Macroglobulinemia, Marginal Zone Lymphoma, or Lymphoplasmacytic Lymphoma. J Clin Oncol. 31(3):301-7.
Nadal N, Chapiro E, Flandrin-Gresta P, Thouvenin S, Vasselon C, Beldjord K, Fenneteau O, Bernard OA, Campos L, NguyenKhac F. LHX2 deregulation by juxtaposition with the IGH locus in a pediatric case of chronic myeloid leukemia in B-cell
lymphoid blast crisis. Leuk Res. 36(9):e195-8.
Perrot A, Pionneau C, Azar N, Baillou C, Lemoine FM, Leblond V, Merle-Béral H, Béné MC, Herbrecht R, Bahram S, Vallat L.
Waldenström's macroglobulinemia harbors a unique proteome where Ku70 is severely underexpressed as compared with
other B-lymphoproliferative disorders. Blood Cancer J. 2:e88.
Puissegur MP, Eichner R, Quelen C, Coyaud E, Mari B, Lebrigand K, Broccardo C, Nguyen-Khac F, Bousquet M, Brousset P. Bcell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b
in progenitor B-cells. Leukemia. 26(10):2224-32.
Thieblemont C, Davi F, Noguera ME, Brière J, Bertoni F, Zucca E, Traverse-Glehen A, Felman P, Berger F, Salles G, Coiffier B.
Splenic marginal zone lymphoma: current knowledge and future directions. Oncology (Williston Park). 26(2):194-202.
Touitou V, Fenollar F, Cassoux N, Merle-Beral H, Lehoang P, Amoura Z, Drancourt M, Bodaghi B. Ocular Whipple's Disease:
Therapeutic Strategy and Long-Term Follow-Up. Ophthalmology. 119(7): 1465-69.
Tsakou E, Agathagelidis A, Boudjoghra M, Raff T, Dagklis A, Chatzouli M, Smilevska T, Bourikas G, Merle-Beral H,
Manioudaki-Kavallieratou E, Anagnostopoulos A, Brüggemann M, Davi F, Stamatopoulos K, Belessi C. Partial versus
productive immunoglobulin heavy locus rearrangements in chronic lymphocytic leukemia: implications for B-cell receptor
stereotypy. Mol Med. 18(1):138-45.
4
Van VQ, Raymond M, Baba N, Rubio M, Wakahara K, Susin SA, Sarfati M. CD47high Expression on CD4 Effectors Identifies
Functional Long-Lived Memory T Cell Progenitors. J Immunol. 188(9):4249-55.
Van VQ, Baba N, Wakahara K, Rubio M, Pancini B, Richard C, Soucy G, Franchimont D, Fortin G, Martinez-Torres AC, Cabon
L, Susin SA, and Sarfati M. CD47Low status on CD4 effectors is necessary for the contraction/resolution of the immune
response in humans and mice. PLoS One, 7(8):e41972.
2011
Billot K, Soeur J, Chereau F, Arrouss I, Merle-Béral H, Huang ME, Mazier D, Baud V, Rebollo A. Deregulation of Aiolos
expression in chronic lymphocytic leukemia is associated with epigenetic modifications. Blood. 117(6):1917-27.
Brugat T, Nguyen-Khac F, Merle-Béral H, Delic J. Concomitant telomere shortening, acquisition of multiple chromosomal
aberrations and in vitro resistance to apoptosis in a single case of progressive CLL. Leuk Res. 35(5):e37-40.
Delavallée L, Cabon L, Galán-Malo P, Lorenzo HK, Susin SA. AIF-mediated caspase-independent necroptosis: a new chance
for targeted therapeutics. IUBMB Life. 63(4):221-32.
Duhoux FP, Ameye G, Lambot V, Herens C, Lambert F, Raynaud S, Wlodarska I, Michaux L, Roche-Lestienne C, Labis E,
Taviaux S, Chapiro E, Nguyen-Khac F, Struski S, Dobbelstein S, Dastugue N, Lippert E, Speleman F, Van Roy N, De Weer A,
Rack K, Talmant P, Richebourg S, Mugneret F, Tigaud I, Mozziconacci MJ, Laibe S, Nadal N, Terré C, Libouton JM,
Decottignies A, Vikkula M, Poirel HA; Groupe Francophone de Cytogénétique Hématologique (GFCH); Belgian Cytogenetic
Group for Hematology and Oncology (BCG-HO). Refinement of 1p36 alterations not involving PRDM16 in myeloid and
lymphoid malignancies. PLoS One. 6(10):e26311.
Eguia B, Bachmeyer C, Charlotte F, Cabannes-Hamy A, Loustau V, Senet P, Davi F, Francès C. Kimura disease with necrosis of
the limbs and mononeuritis multiplex. Clin Exp Dermatol. 36(3):329-31.
Grassin-Delyle S, Buenestado A, Vallat L, Naline E, Marx S, Decocq J, Debré P, Bernard OA, Advenier C, Devillier P, MerleBéral H. Expression and proliferative effect of hemokinin-1 in human B-cells. Peptides. 32(5):1027-34.
Hadzidimitriou A, Agathangelidis A, Darzentas N, Murray F, Delfau-Larue MH, Pedersen LB, Lopez AN, Dagklis A, Rombout P,
Beldjord K, Kolstad A, Dreyling MH, Anagnostopoulos A, Tsaftaris A, Mavragani-Tsipidou P, Rosenwald A, Ponzoni M,
Groenen P, Ghia P, Sander B, Papadaki T, Campo E, Geisler C, Rosenquist R, Davi F, Pott C, Stamatopoulos K. Is there a role
for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases. Blood. 118(11):3088-95.
Kostareli E, Gounari M, Janus A, Murray F, Brochet X, Giudicelli V, Pospisilova S, Oscier D, Foroni L, di Celle PF, Tichy B,
Pedersen LB, Jurlander J, Ponzoni M, Kouvatsi A, Anagnostopoulos A, Thompson K, Darzentas N, Lefranc MP, Belessi C,
Rosenquist R, Davi F, Ghia P, Stamatopoulos K. Antigen receptor stereotypy across B-cell lymphoproliferations: the case of
IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity. Leukemia. 26(5):1127-31.
Langerak AW, Davi F, Ghia P, Hadzidimitriou A, Murray F, Potter KN, Rosenquist R, Stamatopoulos K, Belessi C; European
Research Initiative on CLL (ERIC). Immunoglobulin sequence analysis and prognostication in CLL: guidelines from the ERIC
review board for reliable interpretation of problematic cases. Leukemia. 25(6):979-84.
Le Garff-Tavernier M, Decocq J, de Romeuf C, Parizot C, Dutertre CA, Chapiro E, Davi F, Debré P, Prost JF, Teillaud JL,
Merle-Beral H, Vieillard V. Analysis of CD16+CD56dim NK cells from CLL patients: evidence supporting a therapeutic
strategy with optimized anti-CD20 monoclonal antibodies. Leukemia. 25(1):101-9.
5
Nguyen-Khac F, Chapiro E, Lesty C, Grelier A, Luquet I, Radford-Weiss I, Lefebvre C, Fert-Ferrer S, Callet-Bauchu E, Lippert E,
Raggueneau V, Michaux L, Barin C, Collonge-Rame MA, Mugneret F, Eclache V, Taviaux S, Dastugue N, Richebourg S, Struski
S, Talmant P, Baranger L, Gachard N, Gervais C, Quilichini B, Settegrana C, Maloum K, Davi F, Merle-Béral H. Specific
chromosomal IG translocations have different prognoses in chronic lymphocytic leukemia. Am J Blood Res. 1(1):13-21.
Perrot A, Pionneau C, Nadaud S, Davi F, Leblond V, Jacob F, Merle-Béral H, Herbrecht R, Béné MC, Gribben JG, Bahram S,
Vallat L. A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia. Blood. 118(4):e115.
Put N, Van Roosbroeck K, Konings P, Meeus P, Brusselmans C, Rack K, Gervais C, Nguyen-Khac F, Chapiro E, Radford-Weiss
I, Struski S, Dastugue N, Gachard N, Lefebvre C, Barin C, Eclache V, Fert-Ferrer S, Laibe S, Mozziconacci MJ, Quilichini B,
Poirel HA, Wlodarska I, Hagemeijer A, Moreau Y, Vandenberghe P, Michaux L; on behalf of the BCGHo and the GFCH.
Chronic lymphocytic leukemia and prolymphocytic leukemia with MYC translocations: a subgroup with an aggressive
disease course. Ann Hematol. 91(6):863-73.
Quivoron C, Couronné L, Della Valle V, Lopez CK, Plo I, Wagner-Ballon O, Do Cruzeiro M, Delhommeau F, Arnulf B, Stern MH,
Godley L, Opolon P, Tilly H, Solary E, Duffourd Y, Dessen P, Merle-Beral H, Nguyen-Khac F, Fontenay M, Vainchenker W,
Bastard C, Mercher T, Bernard OA. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a
récurrent évent during human lymphomagenesis. Cancer Cell, 20(1): 25-38.
Sutton L, Chevret S, Tournilhac O, Diviné M, Leblond V, Corront B, Leprêtre S, Eghbali H, Van Den Neste E, Michallet M,
Maloisel F, Bouabdallah K, Decaudin D, Berthou C, Brice P, Gonzalez H, Chapiro E, Radford-Weiss I, Leporrier N, Maloum K,
Nguyen-Khac F, Davi F, Lejeune J, Merle-Béral H, Leporrier M; Société Française de Greffe de Moelle et de Thérapie
Cellulaire (SFGM-TC) and Groupe Français d'étude de la Leucémie Lymphoïde Chronique (GFLLC). Autologous stem cell
transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter, randomized, controlled
trial from the SFGM-TC and GFLLC. Blood. 117(23):6109-19.
Thieblemont C, Davi F, Noguera ME, Brière J. Non-MALT marginal zone lymphoma. Curr Opin Hematol. 18(4):273-9.
Le Garff-Tavernier M, Blons H, Nguyen-Khac F, Pannetier M, Brissard M, Gueguen S, Jacob F, Ysebaert L, Susin SA, and
Merle-Béral H. Functional assessment of p53 in chronic lymphocytic leukemia. Blood Cancer J. 1: e5.
2010
Artus C, Boujrad H, Bouharrour A, Brunelle MN, Hoos S, Yuste VJ, Lenormand P, Rousselle JC, Namane A, England P,
Lorenzo HK, and Susin SA. AIF promotes chromatinolysis and caspase-independent programmed necrosis by interacting
with histone H2AX. EMBO Journal. 29:1585-99.
Baritaud M, Boujrad H, Lorenzo HK, Krantic S, Susin SA. Histone H2AX: The missing link in AIF-mediated caspaseindependent programmed necrosis. Cell Cycle. 9(16):3166-73.
Brugat T, Nguyen-Khac F, Grelier A, Merle-Béral H, Delic J. Telomere dysfunction-induced foci arise with the onset of
telomeric deletions and complex chromosomal aberrations in resistant chronic lymphocytic leukemia cells. Blood.
116(2):239-49.
Brugat T, Gault N, Baccelli I, Maës J, Roborel de Climens A, Nguyen-Khac F, Davi F, Merle-Béral H, Gilson E, Goodhardt M,
Delic J. Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells. Leukemia. 24(1):24651.
Chapiro E, Leporrier N, Radford-Weiss I, Bastard C, Mossafa H, Leroux D, Tigaud I, De Braekeleer M, Terré C, Brizard F,
Callet-Bauchu E, Struski S, Veronese L, Fert-Ferrer S, Taviaux S, Lesty C, Davi F, Merle-Béral H, Bernard OA, Sutton L,
6
Raynaud SD, Nguyen-Khac F. Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in
untreated chronic lymphocytic leukemia (CLL) at advanced stages. Leuk Res. 34(1):63-8.
Chapiro E, Russell L, Lainey E, Kaltenbach S, Ragu C, Della-Valle V, Hanssens K, Macintyre EA, Radford-Weiss I, Delabesse E,
Cavé H, Mercher T, Harrison CJ, Nguyen-Khac F, Dubreuil P, Bernard OA. Activating mutation in the TSLPR gene in B-cell
precursor lymphoblastic leukemia. Leukemia. 24(3):642-5.
Chapiro E, Russell LJ, Struski S, Cavé H, Radford-Weiss I, Valle VD, Lachenaud J, Brousset P, Bernard OA, Harrison CJ,
Nguyen-Khac F. A new recurrent translocation t(11;14)(q24;q32) involving IGH@ and miR-125b-1 in B-cell progenitor acute
lymphoblastic leukemia. Leukemia. 24(7):1362-4.
Couronné L, Lippert E, Andrieux J, Kosmider O, Radford-Weiss I, Penther D, Dastugue N, Mugneret F, Lafage M, Gachard N,
Nadal N, Bernard OA, Nguyen-Khac F. Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid
leukemias. Leukemia. 24(1):201-3.
Darzentas N, Hadzidimitriou A, Murray F, Hatzi K, Josefsson P, Laoutaris N, Moreno C, Anagnostopoulos A, Jurlander J,
Tsaftaris A, Chiorazzi N, Belessi C, Ghia P, Rosenquist R, Davi F, Stamatopoulos K. A different ontogenesis for chronic
lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence. Leukemia.
24(1):125-32.
Geri G, Terrier B, Semoun O, Saadoun D, Sène D, Charlotte F, Merle-Béral H, Musset L, Resche-Rigon M, Cacoub P.
Surrogate markers of B cell non-Hodgkin's lymphoma in patients with hepatitis C virus-related cryoglobulinaemia vasculitis.
Ann Rheum Dis. 69(12):2177-80.
Krantic S, Susin SA. Programmed necrosis: a “new” cell death outcome for injured neurons? Chapter 3 in "Acute Neuronal
Injury: The role of excitotoxic programmed cell death mechanisms", Eds. Fujikawa D.G., pp 35-66, Springer, New York,
Dordrecht, Heidelberg, London.
Le Garff-Tavernier M, Béziat V, Decocq J, Siguret V, Gandjbakhch F, Pautas E, Debré P, Merle-Beral H, Vieillard V. Human
NK cells display major phenotypic and functional changes over the life span. Aging Cell. 9(4):527-35.
Letestu R, Lévy V, Eclache V, Baran-Marszak F, Vaur D, Naguib D, Schischmanoff O, Katsahian S, Nguyen-Khac F, Davi F,
Merle-Béral H, Troussard X, Ajchenbaum-Cymbalista F. Prognosis of Binet stage A chronic lymphocytic leukemia patients:
the strength of routine parameters. Blood. 116(22):4588-90.
Lopez-Royuela N, Perez-Galan P, Galan-Malo P, Yuste VJ, Anel A, Susin SA, Naval J, Marzo I. Different contribution of BH3only proteins and caspases to doxorubicin-induced apoptosis in p53-deficient leukemia cells. Biochem Pharmacol.
79(12):1746-58.
Marincevic M, Cahill N, Gunnarsson R, Isaksson A, Mansouri M, Göransson H, Rasmussen M, Jansson M, Ryan F, Karlsson K,
Adami HO, Davi F, Jurlander J, Juliusson G, Stamatopoulos K, Rosenquist R. High-density screening reveals a different
spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 Bcell receptors. Haematologica. 95(9):1519-25.
Marincevic M, Mansouri M, Kanduri M, Isaksson A, Göransson H, Smedby KE, Jurlander J, Juliusson G, Davi F,
Stamatopoulos K, Rosenquist R. Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing
stereotyped IGHV4-34 B-cell receptors. Haematologica. 95(12):2072-9.
Marteau JB, Rigaud O, Brugat T, Gault N, Vallat L, Kruhoffer M, Orntoft TF, Nguyen-Khac F, Chevillard S, Merle-Beral H,
Delic J. Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in
an aggressive subset of chronic lymphocytic leukemia in males. BMC Med Genomics. 3:53.
7
Nguyen-Khac F. Cytogenetic markers in chronic lymphocytic leukemia. Ann Biol Clin (Paris). 68(3):273-6.
Nguyen-Khac F, Barin C, Chapiro E, Macintyre EA, Romana S, Bernard OA. Cyclin D3 deregulation by juxtaposition with IGH
locus in a t(6;14)(p21;q32)-positive T-cell acute lymphoblastic leukemia. Leuk Res. 34(1):e13-4.
Nguyen-Khac F, Lesty C, Eclache V, Couronné L, Kosmider O, Andrieux J, Collonge-Rame MA, Penther D, Lafage M, BilhouNabera C, Chapiro E, Mozziconacci MJ, Mugneret F, Gachard N, Nadal N, Lippert E, Struski S, Dastugue N, Cabrol C, Bernard
OA; Groupe Francophone de Cytogénétique Hématologique. Chromosomal abnormalities in transformed Ph-negative
myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2
mutations. Genes Chromosomes Cancer. 49(10):919-27.
Roos-Weil D, Nguyen S, Uzunov M, Bories D, Chapiro E, Nguyen-Khac F, Vernant JP, Dhédin N. Therapy-related
myelodysplastic syndrome after allogeneic BMT: successful treatment by donor lymphocyte infusions. Bone Marrow
Transplant. 45(9):1471-3.
2009
Barbier S, Chatre L, Bras M, Sancho P, Roué G, Virely C, Yuste VJ, Baudet S, Rubio M, Esquerda JE, Sarfati M, Merle-Béral H,
Susin SA. Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin
cytoskeleton. Haematologica. 94(4):507-17.
Cornet E, Lesesve JF, Mossafa H, Sébahoun G, Levy V, Davi F, Troussard X; Groupe Français d'Hématologie Cellulaire (GFHC).
Long-term follow-up of 111 patients with persistent polyclonal B-cell lymphocytosis with binucleated lymphocytes.
Leukemia. 23(2):419-22.
Fardeau C, Lee CP, Merle-Béral H, Cassoux N, Bodaghi B, Davi F, Lehoang P. Retinal fluorescein, indocyanine green
angiography, and optic coherence tomography in non-Hodgkin primary intraocular lymphoma. Am J Ophthalmol.
147(5):886-94, 894.
Hadzidimitriou A, Darzentas N, Murray F, Smilevska T, Arvaniti E, Tresoldi C, Tsaftaris A, Laoutaris N, Anagnostopoulos A,
Davi F, Ghia P, Rosenquist R, Stamatopoulos K, Belessi C. Evidence for the significant role of immunoglobulin light chains in
antigen recognition and selection in chronic lymphocytic leukemia. Blood. 113(2):403-11.
Maloum K, Settegrana C, Chapiro E, Cazin B, Leprêtre S, Delmer A, Leporrier M, Dreyfus B, Tournilhac O, Mahe B, NguyenKhac F, Lesty C, Davi F, Merle-Béral H. IGHV gene mutational status and LPL/ADAM29 gene expression as clinical outcome
predictors in CLL patients in remission following treatment with oral fludarabine plus cyclophosphamide. Ann
Hematol. 88(12):1215-21.
Merle-Béral H, Barbier S, Roué G, Bras M, Sarfati M, Susin SA. Caspase-independent type III PCD: a new means to modulate
cell death in chronic lymphocytic leukemia. Leukemia. 23(5):974-7.
Murati A, Gervais C, Carbuccia N, Finetti P, Cervera N, Adélaïde J, Struski S, Lippert E, Mugneret F, Tigaud I, Penther D,
Bastard C, Poppe B, Speleman F, Baranger L, Luquet I, Cornillet-Lefebvre P, Nadal N, Nguyen-Khac F, Pérot C, Olschwang S,
Bertucci F, Chaffanet M, Lessard M, Mozziconacci MJ, Birnbaum D; Groupe Francophone de Cytogénétique Hématologique.
Genome profiling of acute myelomonocytic leukemia: alteration of the MYB locus in MYST3-linked cases. Leukemia.
23(1):85-94.
Russell LJ, Capasso M, Vater I, Akasaka T, Bernard OA, Calasanz MJ, Chandrasekaran T, Chapiro E, Gesk S, Griffiths M,
Guttery DS, Haferlach C, Harder L, Heidenreich O, Irving J, Kearney L, Nguyen-Khac F, Machado L, Minto L, Majid A,
Moorman AV, Morrison H, Rand V, Strefford JC, Schwab C, Tönnies H, Dyer MJ, Siebert R, Harrison CJ. Deregulated
8
expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic
leukemia. Blood. 114(13):2688-98.
Véronèse L, Tournilhac O, Verrelle P, Davi F, Dighiero G, Chautard E, Veyrat-Masson R, Kwiatkowski F, Goumy C, Gouas L,
Bay JO, Vago P, Tchirkov A. Strong correlation between VEGF and MCL-1 mRNA expression levels in B-cell chronic
lymphocytic leukemia. Leuk Res. 33(12):1623-6.
2008
Berger R, Nguyen-Khac F. Chromosomal abnormalities and Waldenström macroglobulinemia. Pathol Biol (Paris). 56(6):4006.
Chapiro E, Radford-Weiss I, Bastard C, Luquet I, Lefebvre C, Callet-Bauchu E, Leroux D, Talmant P, Mozziconacci MJ,
Mugneret F, Struski S, Raynaud S, Andrieux J, Barin C, Jotterand M, Mossafa H, Ramond S, Terré C, Lippert E, Berger F,
Felman P, Merle-Béral H, Bernard OA, Davi F, Berger R, Nguyen-Khac F. The most frequent t(14;19)(q32;q13)-positive B-cell
malignancy corresponds to an aggressive subgroup of atypical chronic lymphocytic leukemia. Leukemia. 22(11):2123-7.
Davi F, Rosenquist R, Ghia P, Belessi C, Stamatopoulos K. Determination of IGHV gene mutational status in chronic
lymphocytic leukemia: bioinformatics advances meet clinical needs. Leukemia. 22(1):212-4.
Derbré S, Gil S, Taverna M, Boursier C, Nicolas V, Demey-Thomas E, Vinh J, Susin SA, Hocquemiller R, Poupon E. Highly
cytotoxic and neurotoxic acetogenins of the Annonaceae: new putative biological targets of squamocin detected by activitybased protein profiling. Bioorg Med Chem Lett. 18(21):5741-4.
de Romeuf C, Dutertre CA, Le Garff-Tavernier M, Fournier N, Gaucher C, Glacet A, Jorieux S, Bihoreau N, Behrens CK,
Béliard R, Vieillard V, Cazin B, Bourel D, Prost JF, Teillaud JL, Merle-Béral H. Chronic lymphocytic leukaemia cells are
efficiently killed by an anti-CD20 monoclonal antibody selected for improved engagement of FcgammaRIIIA/CD16. Br J
Haematol. 140(6):635-43.
Duhamel M, Arrouss I, Merle-Béral H, Rebollo A. The Aiolos transcription factor is up-regulated in chronic lymphocytic
leukemia. Blood. 111(6):3225-8.
Gervais C, Murati A, Helias C, Struski S, Eischen A, Lippert E, Tigaud I, Penther D, Bastard C, Mugneret F, Poppe B, Speleman
F, Talmant P, VanDen Akker J, Baranger L, Barin C, Luquet I, Nadal N, Nguyen-Khac F, Maarek O, Herens C, Sainty D, Flandrin
G, Birnbaum D, Mozziconacci MJ, Lessard M; Groupe Francophone de Cytogénétique Hématologique. Acute myeloid
leukaemia with 8p11 (MYST3) rearrangement: an integrated cytologic, cytogenetic and molecular study by the groupe
francophone de cytogénétique hématologique. Leukemia. 22(8):1567-75.
Murray F, Darzentas N, Hadzidimitriou A, Tobin G, Boudjogra M, Scielzo C, Laoutaris N, Karlsson K, Baran-Marzsak F,
Tsaftaris A, Moreno C, Anagnostopoulos A, Caligaris-Cappio F, Vaur D, Ouzounis C, Belessi C, Ghia P, Davi F, Rosenquist R,
Stamatopoulos K. Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia:
implications for the role of antigen selection in leukemogenesis. Blood. 111(3):1524-33.
Poncet D, Belleville A, t'kint de Roodenbeke C, Roborel de Climens A, Ben Simon E, Merle-Beral H, Callet-Bauchu E, Salles G,
Sabatier L, Delic J, Gilson E. Changes in the expression of telomere maintenance genes suggest global telomere dysfunction
in B-chronic lymphocytic leukemia. Blood. 111(4):2388-91.
Praz F, Le Page F, Vallat L, Davi F, Nguyen-Khac F, Maloum K, Delic J, Merle-Béral H. Absence of microsatellite instability in
human chronic lymphocytic leukaemia B cells. Leukemia. 22(1):186-9.
9
Su X, Della-Valle V, Delabesse E, Azgui Z, Berger R, Merle-Béral H, Bernard OA, Nguyen-Khac F. Transcriptional activation of
the cardiac homeobox gene CSX1/NKX2-5 in a B-cell chronic lymphoproliferative disorder. Haematologica. 93(7):1081-5.
Véronèse L, Tournilhac O, Verrelle P, Davi F, Dighiero G, Chautard E, Veyrat-Masson R, Kwiatkowski F, Goumy C, Vago P,
Travade P, Tchirkov A. Low MCL-1 mRNA expression correlates with prolonged survival in B-cell chronic lymphocytic
leukemia. Leukemia. 22(6):1291-3.
Viala K, Béhin A, Maisonobe T, Léger JM, Stojkovic T, Davi F, Leblond V, Bouche P. Neuropathy in lymphoma: a relationship
between the pattern of neuropathy, type of lymphoma and prognosis? J Neurol Neurosurg Psychiatry. 79(7):778-82.
Yuste VJ, Lorenzo HK, Susin SA. AIFM1 (apoptosis-inducing factor, mitochondrion-associated, 1). Atlas Genet Cytogenet
Oncol Haematol.2008;12(3):190-194.
2007
Akasaka T, Balasas T, Russell LJ, Sugimoto KJ, Majid A, Walewska R, Karran EL, Brown DG, Cain K, Harder L, Gesk S, MartinSubero JI, Atherton MG, Brüggemann M, Calasanz MJ, Davies T, Haas OA, Hagemeijer A, Kempski H, Lessard M, Lillington
DM, Moore S, Nguyen-Khac F, Radford-Weiss I, Schoch C, Struski S, Talley P, Welham MJ, Worley H, Strefford JC, Harrison
CJ, Siebert R, Dyer MJ. Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in
B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Blood. 109(8):3451-61.
Boujrad H, Gubkina O, Robert N, Krantic S, Susin SA. AIF-mediated programmed necrosis: a highly regulated way to die. Cell
Cycle. 6(21):2612-9.
Bras M, Yuste VJ, Roué G, Barbier S, Sancho P, Virely C, Rubio M, Baudet S, Esquerda JE, Merle-Béral H, Sarfati M, Susin
SA. Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. Mol Cell Biol. 27(20):7073-88.
Brüggemann M, White H, Gaulard P, Garcia-Sanz R, Gameiro P, Oeschger S, Jasani B, Ott M, Delsol G, Orfao A, Tiemann M,
Herbst H, Langerak AW, Spaargaren M, Moreau E, Groenen PJ, Sambade C, Foroni L, Carter GI, Hummel M, Bastard C, Davi
F, Delfau-Larue MH, Kneba M, van Dongen JJ, Beldjord K, Molina TJ. Powerful strategy for polymerase chain reaction-based
clonality assessment in T-cell malignancies Report of the BIOMED-2 Concerted Action BHM4 CT98-3936. Leukemia.
21(2):215-21.
Cassoux N, Giron A, Bodaghi B, Tran TH, Baudet S, Davi F, Chan CC, Lehoang P, Merle-Béral H. IL-10 measurement in
aqueous humor for screening patients with suspicion of primary intraocular lymphoma. Invest Ophthalmol Vis Sci.
48(7):3253-9.
Ghia P, Belessi C, Daví F, Rosenquist R, Stamatopoulos K. Reply to 'Male preponderance in chronic lymphocytic leukemia
utilizing IGHV1-69.' When size of the sample matters. Leukemia. 21(12):2539-40.
Choquet S, Trappe R, Leblond V, Jäger U, Davi F, Oertel S. CHOP-21 for the treatment of post-transplant lymphoproliferative
disorders (PTLD) following solid organ transplantation. Haematologica. 92(2):273-4.
Evans PA, Pott Ch, Groenen PJ, Salles G, Davi F, Berger F, Garcia JF, van Krieken JH, Pals S, Kluin P, Schuuring E, Spaargaren
M, Boone E, González D, Martinez B, Villuendas R, Gameiro P, Diss TC, Mills K, Morgan GJ, Carter GI, Milner BJ, Pearson D,
Hummel M, Jung W, Ott M, Canioni D, Beldjord K, Bastard C, Delfau-Larue MH, van Dongen JJ, Molina TJ, Cabeçadas J.
Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets.
Report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia. 21(2):207-14.
10
Gary-Gouy H, Sainz-Perez A, Marteau JB, Marfaing-Koka A, Delic J, Merle-Beral H, Galanaud P, Dalloul A. Natural
phosphorylation of CD5 in chronic lymphocytic leukemia B cells and analysis of CD5-regulated genes in a B cell line suggest
a role for CD5 in malignant phenotype. J Immunol. 179(7):4335-44.
Ghia P, Stamatopoulos K, Belessi C, Moreno C, Stilgenbauer S, Stevenson F, Davi F, Rosenquist R; European Research
Initiative on CLL. ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia.
Leukemia. 21(1):1-3.
Le Garff-Tavernier M, Ticchioni M, Brissard M, Salmon C, Raynaud S, Davi F, Bernard A, Merle-Béral H, AjchenbaumCymbalista F, Letestu R. National standardization of ZAP-70 determination by flow cytometry: the French experience.
Cytometry B Clin Cytom. 72(2):103-8.
Lorenzo HK, Susin SA. Therapeutic potential of AIF-mediated caspase-independent programmed cell death. Drug Resist
Updat. 10(6):235-55.
Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, Susin SA. Sequential activation of
poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.
Mol Cell Biol. 27(13):4844-62.
Planelles L, Castillo-Gutiérrez S, Medema JP, Morales-Luque A, Merle-Béral H, Hahne M. APRIL but not BLyS serum levels
are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival. Haematologica. 92(9):1284-5.
Reix S, Mechawar N, Susin SA, Quirion R, Krantic S. Expression of cortical and hippocampal apoptosis-inducing factor (AIF)
in aging and alzheimer's disease. Neurobiol Aging. 28(3):351-6.
Stamatopoulos K, Belessi C, Moreno C, Boudjograh M, Guida G, Smilevska T, Belhoul L, Stella S, Stavroyianni N, Crespo M,
Hadzidimitriou A, Sutton L, Bosch F, Laoutaris N, Anagnostopoulos A, Montserrat E, Fassas A, Dighiero G, Caligaris-Cappio F,
Merle-Béral H, Ghia P, Davi F. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors:
Pathogenetic implications and clinical correlations. Blood. 109(1):259-70.
Ticchioni M, Essafi M, Jeandel PY, Davi F, Cassuto JP, Deckert M, Bernard A. Homeostatic chemokines increase survival of Bchronic lymphocytic leukemia cells through inactivation of transcription factor FOXO3a. Oncogene. 26(50):7081-91.
Touitou V, Daussy C, Bodaghi B, Camelo S, de Kozak Y, Lehoang P, Naud MC, Varin A, Thillaye-Goldenberg B, Merle-Béral H,
Fridman WH, Sautès-Fridman C, Fisson S. Impaired th1/tc1 cytokine production of tumor-infiltrating lymphocytes in a
model of primary intraocular B-cell lymphoma. Invest Ophthalmol Vis Sci. 48(7):3223-9.
van Krieken JH, Langerak AW, Macintyre EA, Kneba M, Hodges E, Sanz RG, Morgan GJ, Parreira A, Molina TJ, Cabeçadas J,
Gaulard P, Jasani B, Garcia JF, Ott M, Hannsmann ML, Berger F, Hummel M, Davi F, Brüggemann M, Lavender FL, Schuuring
E, Evans PA, White H, Salles G, Groenen PJ, Gameiro P, Pott Ch, Dongen JJ. Improved reliability of lymphoma diagnostics via
PCR-based clonality testing: report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia. 21(2):201-6.
11