____________________ ____________________ ____________________ ____________________ Intro to Genetics Quiz Select the correct answer. Record your answers in the box to the left. Answer Box 1. _______ 2. _______ 3. _______ 4. _______ 5. _______ 1. Heterozygous means ______. a. Information about heritable traits b. having a pair of identical (same) alleles on a gene c. crossing over results d. having a pair of non-identical alleles on a gene 2. Homozygous means_____. a. Information about heritable traits b. mixed/ different forms of a gene that are possible c. having a pair of identical (same) alleles on a gene d. Observable (expressed) Inherited traits e. having a pair of non-identical alleles on a gene 3. An allele is _______. a. Observable (expressed) Inherited traits b. unique/ different forms of a gene that are possible c. particular genes carried by an individual d. crossing over results e. having a pair of non-identical alleles on a gene 4. Genotype is _______. a. Observable (expressed, can physically see) Inherited traits b. mixed/ different forms of a gene that are possible c. particular genes carried by an individual d. crossing over results e. having a pair of non-identical alleles on a gene 5. Phenotype is ________. a. Observable (expressed, can physically see) Inherited traits b. mixed/ different forms of a gene c. particular genes carried by an individual d. crossing over results e. having a pair of non-identical alleles on a gene ____________________ ____________________ ____________________ ____________________ 6. A dominant allele _______. Answer Box a. is represented by a capital letter, such as “A” b. is represented by a lower case letter, such as “a” 6. _______ c. has the ability to mask other traits d. both a and c e. both b and c 7. _______ 8. _______ 9. _______ 10. _______ 11. _______ 12. _______ 13. _______ 14. _______ 7. A recessive allele ________. a. is represented by a capital letter, such as “A” b. is represented by a lower case letter, such as “a” c. has the ability to mask other traits d. both a and c e. both b and c 8. Hybrid offspring _______. a. is when offspring inherit a pair of identical alleles for a trait b. is when offspring inherit a pair of non-identical alleles for a trait. 9. Diffusion is ___________. a. use of energy to move materials b. division of nuclear materials c. movement of materials from high concentration to low concentration 10. Mitosis is ___________. a. use of energy to move materials b. division of nuclear materials c. movement of materials from high concentration to low concentration 11. Cellular respiration is _______________. a. production of food b. the process of breathing c. production of energy 12. Mitosis produces _____ identical cell(s). a. one b. two c. three d. four 13. DNA is not made up of ____________. a. water b. phosphate c. sugar d. nitrogen bases 14. Which nitrogen base bonds with cytosine? a. adenine b. guanine c. thymine d. cytosine ____________________ ____________________ ____________________ ____________________ Application Use the information for SpongeBob’s traits to write the phenotype for each item. Answer Box 15. _______ 16. _______ 15. Ll: __________________ 17. Ss: __________________ 17. _______ 18. rr: ____________________ and a black female produces three male kittens. What color are the kittens? How do you know? 19. Draw a picture of SpongeBob based on the traits identified above. (8pts) 18. _______ 20. _______ 20. Which cell illustrates prophase? 21. _______ 21. Which cell illustrates anaphase? 22. _______ 16. YY: __________________ ____________________ ____________________ ____________________ ____________________ THURSDAY, Feb. 9 (HealthDay News) -- Four new genes associated with type 2 diabetes have been identified by researchers, who also pinpointed six independent diabetes-associated genes at previously known locations on chromosomes. The results offer valuable insight into the genetic risk for type 2 diabetes in multiple ethnic groups and could help lead to new treatments, according to a journal news release. A number of environmental and genetic factors are associated with type 2 diabetes. "Together, known [type 2 diabetes] genetic versions explain only about 10 percent of the genetic variance, indicating that additional genetic factors are likely to contribute to disease risk," senior study co-author Dr. Brendan Keating, of The Children's Hospital of Philadelphia, said in the news release. "Further, previous studies have been based almost exclusively on individuals of European ancestry, and genetic contributors to [type 2 diabetes] are less well understood in non-European populations," he added. "An important first step towards understanding genetic risk across populations is to establish whether known [diabetes-associated] genes span ethnicities or are population-specific." Keating and an international team of colleagues analyzed 39 multiethnic studies on type 2 diabetes that included more than 17,000 people with diabetes and 70,000 people without the disease. "As a result of our large-scale genetic analysis, we uncovered previously unknown multiethnic genetic variations and confirmed that, together, known genetic risk factors influence [type 2 diabetes] risk in multiethnic populations, including African-Americans, Hispanics and Asians," senior co-author Richa Saxena, of Massachusetts General Hospital and Harvard Medical School. Saxena said that identifying new genes associated with type 2 diabetes in diverse ethnic groups could eventually guide strategies for developing treatments. 22. How many new genes associated with type 2 diabetes were found? a. one b. two c. three d. four 23. What makes this discovery so valuable? _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ _____________________________________________________________________________ ____________________ ____________________ ____________________ ____________________ ANSWERS 1. E. having a pair of non-identical alleles at a gene locus 2. C. having a pair of identical (same) alleles at a gene locus 3. B. unique/ different molecular forms of a gene that are possible at a given locus 4. C. particular genes carried by an individual 5. A. Observable (expressed, can physically see) Inherited traits 6. D. both a and c 7. B. is represented by a lower case letter, such as “a” 8. B. is when offspring of genetic crosses inherit a pair of non-identical alleles for a trait. 12. Ee x ee yields Geno- ½ Ee, ½ ee Pheno- ½ free, ½ attached ratio of 1:1 E e e Ee ee Ee ee 13. Ee x Ee yields Geno- ¼ EE, ½ Ee and ¼ ee Pheno- ¾ free, ¼ attached Ratio of 1:2:1 E e EE Ee Ee ee 14. e E e Each parent is homozygous for a trait. Geno- TT, tt ____________________ ____________________ ____________________ ____________________ 15. GGSs x Ggss yields Geno- ¼ GGSs, ¼ GGss, ¼ GgSs, ¼ Ggss Pheno- ½ Green, Short, ½ Green, Long GS Gs GS Gs Gs GGSs GGss GGSs GGss GGSs GGss GGSs GGss Gs GGSs GGss GGSs GGss gs GGSs GGss GGSs GGss gs 16. ggSS x GgSs yields Geno- ¼ GgSS, ¼ GgSs, ¼ ggss, ¼ ggSs Pheno- ½ green, short, ½ striped, short gS gS gS gS GS GgSS GgSS GgSS GgSS GgSs GgSs GgSs GgSs Gs ggSS ggSS ggSS ggSS gS ggSs ggSs ggSs ggSs gs 17. TNTL x TNTL yields Geno- ¼ TNTN, ½ TNTL, ¼ TLTL Pheno- ¼ no tail, ½ short tail, ¼ long tail N = no tail, L = long tail TN TL TNTN TNTL TNTL TLTL TN TL ____________________ ____________________ ____________________ ____________________ 18. The kittens are all black. The key to the problems is that all the kittens are male XY. Each has only one X chromosome, which were inherited from the mother. Since the mother is black, a trait produces by a recessive allele, any X chromosome from the mother must carry the allele for black coat color. That means the kittens would be XyY or black in color. 19. XCY x XNXC yields Geno- ¼ XCXN, ¼ XNY, ¼ XCXC, ¼ XCY Pheno- ¼ normal female, ¼ colorblind female ¼ normal male, ¼ colorblind male C = colorblind, N = normal, XX = female, XY = male XC Y XCXN XNY XCXC XC Y XN XC