PUBLICATIONS 2006 UAB Anesthesiology Department Peer-Reviewed Articles *Audu P, Nielsen VG, Armstead V, Powell G, Kim J, Kim L, Mehta M. The impact of tissue factor pathway inhibitor on coagulation kinetics determined by thrombelastography. Anesth Analg. 2006 Oct;103(4):841-5 *Boudreaux AM. Commentary on Liang BA. Special doctor's docket. Lethal injection: policy considerations for medicine. J Clin Anesth. 2006 Sep;18(6):466-70 *Chen L, Patel RP, Teng X, Bosworth CA, Lancaster JR Jr, Matalon S. Mechanisms of cystic fibrosis transmembrane conductance regulator activation by s-nitrosoglutathione. J Biol Chem. 2006 Apr 7;281(14):9190-9 *Crawford JH, Isbell TS, Huang Z, Shiva S, Chacko BK, Schechter AN, Darley-Usmar VM, Kerby JD, Lang JD Jr, Kraus D, Ho C, Gladwin MT, Patel RP. Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood. 2006 Jan 15;107(2):566-74 *Davis IC, Lazarowski ER, Hickman-Davis JM, Fortenberry JA, Chen FP, Zhao X, Sorscher E, Graves LM, Sullender WM, Matalon S. Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus. Am J Respir Crit Care Med. 2006 Mar 15;173(6):673-82 *Froelich MA, Burchfield DJ, Euliano TY, Caton D. A single dose of fentanyl and midazolam prior to Cesarean section have no adverse neonatal effects. Can J Anesth 53(1):79-85, January 2006 *Griguer CE, Oliva CR, Kelley EE, Giles GI, Lancaster JR Jr, Gillespie GY. Xanthine oxidase-dependent regulation of hypoxia-inducible factor in cancer cells. Cancer Res. 2006 Feb 15;66(4):2257-63 Guevara-Lopez U, Covarrubias-Gomez A, Gutierrez-Acar H, Aldrete JA, Lopez-Munoz FJ, Martinez-Benitez B. Chronic subarachnoid administration of 1-(4chlorobenzoyl)-5methoxy-2methyl-1H-indole-3 acetic acid (indomethacin): an evaluation of its neurotoxic effects in an animal model. Anesth Analg. 2006 Jul;103(1):99-102 *Hall NG, Liu Y, Hickman-Davis JM, Davis GC, Myles C, Andrews EJ, Matalon S, Lang Jr JD. Bactericidal Function of Alveolar Macrophages in Mechanically Ventilated Rabbits. Am J Respir Cell Mol Biol. 34(6): 719-726, June 2006 *Hickman-Davis JM, Davis IC. Transgenic mice. Paediatr Respir Rev. 2006 Mar;7(1):49-53 *Hickman-Davis JM, McNicholas-Bevensee C, Davis IC, Ma HP, Davis GC, Bosworth CA, Matalon S. Reactive species mediate inhibition of alveolar type II sodium transport during mycoplasma infection. Am J Respir Crit Care Med. 2006 Feb 1;173(3):334-44 *Ji HL, Su XF, Kedar S, Li J, Barbry P, Smith PR, Matalon S, Benos DJ. Delta-subunit confers novel biophysical features to alpha beta gammahuman epithelial sodium channel (ENaC) via a physical interaction. J Biol Chem. 2006 Mar 24;281(12):8233-41. Epub 2006 Jan 19 *Kelley EE, Hock T, Khoo NK, Richardson GR, Johnson KK, Powell PC, Giles GI, Agarwal A, Lancaster JR Jr, Tarpey MM. Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells. Free Radic Biol Med. 2006 Mar 15;40(6):952-9 *Kotamraju S, Matalon S, Matsunaga T, Shang T, Hickman-Davis JM, Kalyanaraman B. Upregulation of immunoproteasomes by nitric oxide: Potential antioxidative mechanism in endothelial cells. Free Radic Biol Med. 2006 Mar 15;40(6):1034-44. Epub 2005 Nov 17 Kwak YL, Jones KA, Warner DO, Perkins WJ. Prolonged relaxation consistent with persistent soluble guanylyl cyclase activation in canine pulmonary artery following brief treatment with nitric oxide donors. Life Sci. 2006 Oct 19;79(21):2001-9 *Lancaster JR Jr, Xie K. Tumors face NO problems? Cancer Res. 2006 Jul 1;66(13):6459-62 *Lancaster JR Jr. Nitroxidative, nitrosative, and nitrative stress: kinetic predictions of reactive nitrogen species chemistry under biological conditions. Chem Res Toxicol. 2006 Sep;19(9):1160-74 *Mandabach MG, Wright AJ. The American society of Regional Anesthesia: a concise history of the original group--its birth, growth, and eventual dissolution. Reg Anesth Pain Med 31(1): 53-65, January-February 2006 *Mathru M, Pollard V, He G, Varma TK, Ahmad M, Prough DS. Left ventricular diastolic filling characteristics are not impaired but systolic performance was augmented in the early hours of experimental endotoxemia in humans. Shock 2006; 25(4): 338-343 *Mathru M, Solanki DR, Woodson LC, Funston JS, Ozkan O, Henkel SN, Wang D, Gore D, Prough DS. Splanchnic Oxygen Consumption Is Impaired during Severe Acute Normovolemic Anemia in Anesthetized Humans. Anesthesiology. 2006 Jul;105(1):37-44 *Matz PG, Mooore TA II, Wolff CL IV, Hadley MN. Cervical spinal kyphotic deformity: a comparative cohort study analyzing success of surgical correction. Spinal Surgery 2006; 20(2): 77-85 * Moore TA 2nd, Markert JM, Knowlton RC. Dexmedetomidine as rescue drug during awake craniotomy for cortical motor mapping and tumor resection. Anesth Analg. 2006 May;102(5):1556-8 *Nakayama T, Penheiter AR, Penheiter SG, Chini EN, Thompson M, Warner DO, Jones KA. Differential effects of volatile anesthetics on M3 muscarinic receptor coupling to the Galphaq heterotrimeric G protein. Anesthesiology. 2006 Aug;105(2):313-24 * Ness TJ, Randich A. Which spinal cutaneous nociceptive neurons are inhibited by intravenous lidocaine in the rat? Reg Anesth Pain Med 31: 248253, 2006 *Nielsen VG. Hemodilution modulates the time of onset and rate of fibrinolysis in human and rabbit plasma. J Heart Lung Transplant. 2006 Nov;25(11):1344-52. *Nielsen VG, Steenwyk BL, Gurley WQ. Contact activation prolongs clot lysis time in human plasma: role of thrombin-activatable fibrinolysis inhibitor and Factor XIII. J Heart Lung Transplant. 2006 Oct;25(10):1247-52 *Nielsen VG. Protamine enhances fibrinolysis by decreasing clot strength: role of tissue factor-initiated thrombin generation. Ann Thorac Surg 81: 1720-1727, 2006 *Nielsen VG. Effects of Hextend hemodilution on plasma coagualation kinetcs in the rabbit: role of factor XIII-mediated fibrin polymer crosslinking. J Surg Res 2006; 132: 17-22 *Nielsen VG. Effect of aprotinin on plasma coagulation kinetics determined by thromboelastography: role of Factor XI. Acta Anaesthesiol Scand 50: 168-172, 2006 *Nielsen VG, Steenwyk BL, Gurley WQ, Pereira SJ, Lell WA , Kirklin JK. Argatroban, bivalirudin, and lepirudin do not decrease clot propagation and strength as effectively as heparin-activated antithrombin in vitro. J Heart Lung Transplant. 2006 Jun;25(6):653-63 *Nielsen VG, Cohen BM, Cohen E. Elastic modulus-based thromboelastographic quantification of plasma clot fibrinolysis with progressive plasminogen activation. Blood Coagul Fibrin 17(1): 75-81, January 2006 *Randich A, Uzzell T, Cannon R, Ness TJ. Inflammation and enhanced nociceptive responses to bladder distension produced by intravesical zymosan in the rat. BMC Urol. 2006 Feb 9;6:2 *Randich A, Uzzell T, DeBerry JJ, Ness TJ. Neonatal urinary bladder inflammation produces adult bladder hypersensitivity. J Pain. 2006 Jul; 7(7):469-79 *Robbins MT, Uzzell TW, Aly S, Ness TJ. Characterization of thalamic neuronal responses to urinary bladder distention, including the effect of acute spinal lesions in the rat. J Pain. 2006 Mar;7(3):218-24 Book Chapters *Ness TJ. Visceral pain. In: Von Roenn JH, et al, eds. Current Diagnosis and Treatment of Pain. Lange Medical Books, 2006, pp 136-149 *Ness TJ. Visceral pain. In: de Leon-Casasola OA, ed. Cancer Pain: Pharmacologic, Interventional, and Palliative Approaches. Saunders, 2006, pp 85-94 Correspondence *Albin MS. Letter to the editor. Mayo Anesthesiology Alumni Newsletter 5(2): 14-15, May 2006 *Albin MS, Wills J, Schwend RM. Patent foramen ovale and unexplained stroke. NEJM 354(6): 1753, April 20, 2006 *Aldrete JA. American Board of Anesthesiology examination versus simulators. Anesth Analg 2006 November; 103(5): 1328 *Aldrete JA. W.T.G. Morton to hit the (Northwest) Highway? ASA Newsletter 2006 October; 70(10): 28 [letter] *Aldrete JA. The posterior epidural space is largest at the level of the disc. Anesth Analg 2006 September; 103(3): 781-782 *Defalque RJ. Does the bevel orientation of spinal needles matter? Acta Anaesthesiol Scand 50: 647-648, 2006 *Defalque RJ, Wright AJ. Edison's anesthetic. Anesthesiology 2006 November; 105(5): 1063 *Ho KY, Nagi PA, Gray L, Huh BK. An Alternative Approach to Ganglion Impar Neurolysis under Computed Tomography Guidance for Recurrent Vulva Cancer. Anesthesiology. 2006 Oct;105(4):861-2 Miscellaneous *Aldrete JA. Suspecting and diagnosing arachnoiditis. Practical Pain Management 6(1): 72-74, 76-78, 80-83, January-February 2006 *Aldrete JA, Guevara U. Epidural indomethacin alternative in adult onset diabetics. Practical Pain Management 6(2): 46-47, 51, March 2006 *Boudreaux AM. What’s in it for me? ASA Newsletter 2006 October; 70(10): 3, 9 *Boudreaux A. Volunteerism begins at home. ASA Newsletter 70(9): 22-23, September 2006 *Brockwell RC. The anesthesia machine: what's new besides the name? ASA Newsletter 70(5): 34-35, May 2006 *Chestnut DH, ed. Abram SE, Black S, Gravlee GP, Lee HT, Mathru M, Roizen MF, assoc. eds. Year Book of Anesthesiology and Pain Management 2006. Elsevier Mosby, 2006 *Defalque RJ. Review of Marie-Therese Cousin, L’Anesthesie-Reanimation en France. Des Origines a 1965. 2 vols. Paris: L’Harmattan Editions, 2005. Eur J Anaesthesiol 2006; 23: 718 *Defalque RJ. Causalgia: an unknown contribution. Bulletin of Anesthesia History 24(2): 26-28, April 2006 *Defalque RJ, Wright AJ. Quistorp and "Anaesthesia" in 1718. Bulletin of Anesthesia History 24(1): 5-8, January 2006 *Perrin LS, Froelich M. CON: The BIS monitor should NOT be required for Cesarean sections. SOAP Newsletter 2006 September pp 5-6 *Watson RD Jr, Wright AJ. Anesthesia as women's work: the historical role of the female anesthetist. Bulletin of Anesthesia History 24(2): 17, 20, April 2006 *Wright AJ. From the literature. Bull Anesth History 2006 October; 24(3): 4546 *Wright AJ. This month in anesthesia history. Bull Anesth History 2006 October; 24(3): 46-48 *Wright AJ. From the literature. Bulletin of Anesthesia History 24(2): 30-31, April 2006 *Wright AJ. From the literature. Bulletin of Anesthesia History 24(1): 12-13, January 2006 ASA2006 Abstracts A60 Blood Loss during Thoracolumbar Stabilization and Fusion Procedures Thomas A. Moore II, M.D., Charles L. Wolff III, M.D., Bassam Hadi, M.D., Mark N. Hadley, M.D. 1. Isovolemic hemodilution is a safe alternative to blood transfusion. 2. Intraoperative blood salvage is encouraged for trauma and degenerative disease involving four or more levels. A150 View: • Abstract The History of Anesthesia for Liver Transplantation J. Antonio Aldrete, M.D., M.S., Thomas E. Starzl, Ph.D., M.D. For the first 178 transplants anesthesia techniques were deviced to provide compatibility with diseased liver, anhepatic state and transplanted organ. Metabolic changes, extensive bleeding, hypothermia and anesthetic metabolism problems were found, measured and corrected. A158 View: • Abstract Balloons and Medical Gases: The Collaboration of James Sadler and Thomas Beddoes Amos J. Wright, M.L.S. In the late eighteenth century, early ballooning and early research on the human inspiration of gases combined in the collaboration of James Sadler and Thomas Beddoes. This collaboration is one of the earliest examples of the medical-industrial research efforts so common today. View: • Abstract A345 ESI vs Paravertebral Reduced Steroids, Dipirona and Propoxyphene for Postlaminectomy Syndrome J. Antonio Aldrete, M.D., M.S., Uriah Guevara, M.D., O. L. Ceraso, M.D., H. J. Arenoso, M.D. Patients having post laminectomy syndrome were treated with ESI with MTP or a reduced dose of MTP, PPX and DPN, administered paravertebral, at L 4 -L 5 and L 5 -S 1 , bilateral. Both were effective, but morbidity was greater in patients receiving ESI. A407 View: • Abstract Mechanism(s) of Volatile Anesthetics (VA) Inhibition of Agonist-Promoted M3Gαq Nucleotide Exchange Tetsuzo Nakayama, M.D., Ph.D., Masao Hayashi, M.D., David O. Warner, M.D., Alan R. Penheiter, Ph.D., Keith A. Jones, M.D. Halothane is allosterically inhibiting the modulatory effect of nucleotide-free Gα on agonist-GPCR affinity. A411 View: • Abstract Role of Caveolae to Volatile Anesthetics (VA) Inhibition of Agonist-Promoted M3Gαq Nucleotide Exchange Tetsuzo Nakayama, M.D., Ph.D., Masao Hayashi, M.D., Alan R. Penheiter, Ph.D., David O. Warner, M.D., Anthony K. Jones, M.D. The effect of halothane on M 3 activation of Gα q nucleotide exchange is not due to effects on membrane interactions mediated by caveolin. A596 View: • Abstract The Effect of CPB on Outcome in Patients Undergoing Bilateral Lung Transplantation William A. Lell, M.D., Hunter J. Reynolds, D.O., David C. McGiffin, M.D., Quinton W. Gurley, M.D., Gilbert Ritchie, Ph.D. Patients with PH or PF and longer ischemic times are more likely to require CPB during BLT. CPB is associated with longer postop intubation but has no adverse effect on survival. A1329 View: • Abstract Can Anesthesiologists Identify Lumbar Discopathy in MRI's That Would Indicate ESI? J. Antonio Aldrete, M.D., M.S., Luis A. Vascello, M.D., Sean C. Sardam, B.S., B.A., M.C.S.E., Ramsis F. Ghaly, M.D., Frederika H. Montpetit. Of 86 ABA and PM certified MD's, 48 (55%) answered 5 or more (out of 10) questions correctly. Of 95 ABA certified MD's 20 (21%) did. PM certified MD's appeared to have better knowledge of MRI interpretation. View: • Abstract A1447 Title: Authors(s): Topic: Effects of Inhaled Nitric Oxide on Human Orthotopic Liver Transplantation Jack H. Crawford, M.D., Ph.D., Alvin B. Smith, M.D., Luc Frenette, M.D., Rakesh P. Patel, Ph.D., John D. Lang, M.D. EXPERIMENTAL CIRCULATION View Files: • HTML | Printable Version A1480 Intravenous Sevoflurane Administration in Pigs Connected to a Rebreathing Anesthetic System Pablo Otero, D.V.M., Lisa Tarragona, D.V.M., Alfredo Birger, M.D., Diana Quiroga, M.D., J. Antonio Aldrete, M.D., M.S. Intravenous infusion of sevoflurane (induction: 0.1 mL/kg/min; maintenance: 0.0065 mL/kg/min) to pigs produced stable alveolar concentrations (2.2 vol%) and an acceptable degree of central depression. A1626 View: • Abstract β-Barrel Protein Modified To Enhance Volatile Anesthetic Binding Joshua D. Spencer, M.S., John H. Streiff, Ph.D., Alan R. Penheiter, Ph.D., Keith A. Jones, M.D. Mutagenesis directed by molecular modeling was used to create a VA binding site within a fatty acid binding protein. The site was created within the fatty acid binding pocket, which did not change the binding properties of the protein. View: • Abstract