IDEA SUBMISSION SU2C-FARRAH FAWCETT FOUNDATION INITIATIVE CALL FOR IDEAS AACR and The Farrah Fawcett Foundation call upon members of the cancer community to contribute their ideas to the groundbreaking SU2C-Farrah Fawcett Foundation Human Papillomavirus (HPV) Translational Research Team Grant. We invite submission of ideas for a multidisciplinary translational cancer research project that addresses critical problems in HPV-related cancers and that can deliver near-term patient benefit through investigation by a Team of two expert investigators. The selected grant will include a translational component, and have the potential for a significant impact for patients with HPV-related cancers. The proposal should include clear plans indicating how the work will be translated into the clinic and deliver near-term benefits to patients with HPV-related cancers. Examples of research areas of interest may include: new promising treatment modalities; molecular mechanisms by which HPV causes cancer to develop and metastasize; development of a new generation of targeted treatments; or, improved or novel methods of either diagnosing HPV-related cancers or monitoring the effects of treatment. This grant will provide $1 million over 3 years. The Team may be either inter- or intra-institutional, and both scientists on the Team must hold tenure-track academic appointments. The ideas should be based on perceived opportunities for success as well as highpriority areas with a critical need for rapid progress beyond current medical care. The collective ideas for Team translational research projects suggested by the cancer community will assist the SU2C-Farrah Fawcett Foundation Joint Scientific Advisory Committee (JSAC) in selecting the most promising ideas to be submitted as full research proposals. The Committee will select a SU2C-Farrah Fawcett Foundation Human Papillomavirus (HPV) Translational Research Team Grant from the invited proposals. *Please note that in this call for ideas the AACR is not accepting research proposals for grant funding. Rather, the AACR is inviting ideas to be submitted in a Letter of Intent for the SU2C-Farrah Fawcett Foundation Human Papillomavirus (HPV) Translational Research Team. A subset of ideas will be selected for submission of full research proposals for further consideration. The SU2C-Farrah Fawcett Foundation Human Papillomavirus (HPV) Translational Research Team will be awarded up to $1 million over the 3year term of the grant. IDEA SUBMISSION INSTRUCTIONS Letters of Intent must be submitted by 12:00 p.m. (Noon) ET on Wednesday, November 6, using the proposalCENTRAL website at https://proposalcentral.altum.com. GETTING STARTED IN proposalCENTRAL If you are a new user of proposalCENTRAL, follow the “REGISTER” link and complete the registration process. After you register, complete your Professional Profile (second tab from the left) before starting the application. If you are already registered with proposalCENTRAL, access the site and log in with your Username and password. If you have forgotten your password, click on the “Forgot your password?” link. Supply your e-mail address or your User ID in the space provided; your password will be sent to you by e-mail. To start a Letter of Intent, select the Grant Opportunities tab (gray tab furthest to the right). A list of grant mechanisms will be displayed. Filter the list by searching for American Association for Cancer Research. Search for the Program titled “SU2C-FFF HPV Translational Research Team Grant” and click the “Apply Now” link (second to last column) to create your Letter of Intent. 1 IDEA SUBMISSION SU2C-FARRAH FAWCETT FOUNDATION INITIATIVE Complete all fields in the Letter of Intent and the template that is provided. Upload all requested documents in portable document format (PDF). See the proposalCENTRAL FAQ section, https://proposalcentral.altum.com/FAQ/FrequentlyAskedQuestions.asp, for more information. If you have any difficulties registering, logging in, or creating your Letter of Intent, contact proposalCENTRAL Customer Support immediately: Phone: (800) 875-2562 or (703) 964-5840 E-mail: pcsupport@altum.com THE FOLLOWING INFORMATION IS REQUIRED TO SUBMIT A COMPLETE LETTER OF INTENT: Submissions must be no longer than two (2) pages and utilize no smaller than 11 point type (font) size. Submissions must include the following elements: Project Summary Statement – Briefly describe the idea for a multidisciplinary translational research project and provide justification for the suggestions with background information. Clinical Impact – Describe how forming an HPV translational research Team would result in more rapid advances in therapeutic interventions for HPV-related cancers and deliver near-term patient benefit. Provide a timeline– toward realizing the clinical impact. Approach – Describe the expertise needed to undertake the translational cancer research project. Key Literature References – References to publications supporting the suggestion may be included. ELIGIBILITY CRITERIA This grant will fund a multidisciplinary translational cancer research project that addresses critical problems in HPV-related cancers and that can deliver near-term patient benefit through investigation by a Team of two expert investigators. Neither members of the SU2C-Farrah Fawcett Foundation JSAC nor members of their individual laboratories are eligible for funding as part of the HPV Team. There are no citizenship or residency status restrictions. Please refer to the Program Guidelines for more details. Candidates with a question about the eligibility requirements are encouraged to contact the AACR’s Scientific Review and Grants Administration Department (SRGA) at SU2C@aacr.org prior to submitting the proposal. IDEA SUBMISSION DEADLINE Wednesday, November, 6, 2013 by 12:00 p.m. (noon) Eastern QUESTIONS? E-mail (preferred): Phone: SU2C@aacr.org (267) 765-1049 2 IDEA SUBMISSION SU2C-FARRAH FAWCETT FOUNDATION INITIATIVE I. IDEA SUBMITTER CONTACT INFORMATION Full Name: Last (Family) Degree: M.D. First (Given) Ph.D. M.D., Ph.D. Pharm.D. Middle Initial Other: Title/Position: Department: Institution: Mailing Address: City State/Province Postal Code Country: Telephone: Country code (City code) Telephone number E-mail: Assistant’s Name: Last (Family) First (Given) Middle Initial Assistant’s E-mail: PERMISSION STATEMENT: By submitting an idea for a SU2C-FFF HPV Translational Research Team Grant, the submitter is giving permission for the AACR to use the idea in any manner related to the SU2C-Farrah Fawcett Foundation initiative. However, this permission does not preclude the submitter from using the idea for other purposes. Please check this box to indicate that you have read and agree to the permission statement. 3 IDEA SUBMISSION SU2C-FARRAH FAWCETT FOUNDATION INITIATIVE II. IDEA SUBMISSION (LETTER OF INTENT) Must be no more than 2 pages in length (excluding references) Project Summary Statement – Briefly describe the idea for a multidisciplinary translational research project and provide justification for the suggestions with background information. Clinical Impact – Describe how forming an HPV translational research Team would result in more rapid advances in therapeutic interventions for HPV-related cancers and deliver near-term patient benefit. Provide a timeline– toward realizing the clinical impact. Approach – Describe the expertise needed to undertake the translational cancer research project Key Literature References – References to publications supporting the suggestion may be included. 4