Tracy Walker, DVM The Healthy Horse Route 1 Box 115 Elkins, WV 26241 (304) 636-8363 Late Spring 2006 Vaccines Part 2 In the last newsletter we discussed the basic types of vaccine. Remember that all vaccines are not created equal and not all vaccines are appropriate for every horse. This month we will discuss vaccines available for specific diseases. Core Vaccines for Horses in West Virginia - These vaccines should be given to all horses regardless of environment or use. Keep in mind that this is list is specifically for horses in this area of West Virginia. Remember, mares should receive their annual vaccinations in the last 30 days of pregnancy. This maximizes the safety of the foal and the mare. Tetanus Toxoid Eastern & Western Encephalitis Influenza Rabies West Nile Virus Symptoms The bacteria that causes tetanus is found all over barnyards in mud and fecal matter. Horses are very sensitive to the toxin released by this bacteria. Most horses become infected via an open wound, although an incriminating wound is not always found. An affected horse will become paralyzed in a stiff position. In the early stages, this disease can be treated but most often it results in death. This disease is caused by a virus that is carried by mosquitos. Humans can also be infected by mosquitos. This disease will cause neurologic symptoms such as dementia, difficulty walking, and seizures. This disease can be treated but most often results in death. Horses that survive this disease often have permanent neurologic problems. This disease can cause moderate to severe respiratory disease which could predispose your horse to developing pneumonia. Interval * Annual Booster * Boosters are often given when a wound occurs. Safety & Effectiveness This vaccine is very effective. Reactions may occur but are very rare. * Annual Booster This booster is most effective when given in the Spring to maximize immunity during the mosquito season. Annual Booster with the killed vaccine. This vaccine is very effective. Reactions may occur but are very rare. An intranasal vaccine for flu is available. It is very effective but immunity does not last as long as the intramuscular vaccine. This intranasal vaccine is recommended for horses that are frequently stressed, traveling, shown and campaigned. This vaccine should be boostered every 3 months. The intranasal vaccine should not be used in pregnant mares. Every 3 months with the intranasal vaccine. This disease is caused by a virus that is carried by bats, raccoons, oppossums and fox (just to name a few). The disease is transferred most often by a bite or contact with saliva of an infected animal. In horses, this disease will cause neurologic symptoms such as depression, & coma. Aggressive behaviour may or may not occur. All animals infected with rabies will die from neurologic symptoms or are humanely euthanized due to the danger of human infection. This disease is caused by a virus that is carried by mosquitos. Early signs may include mild hindlimb lameness and facial twitching. Affected horses may have mild signs or progress to seizures and death. Annual Booster Annual Booster This booster is most effective when given in the Spring to maximize immunity during the mosquito season. This vaccine is very effective. I usually give the killed vaccine as a combination with the “4way”. The intranasal vaccine is superior in effectiveness to the intramuscular vaccine, but requires frequent boosters. This vaccine is very effective. Reactions may occur but are very rare. This vaccine is very effective. Horse Owner’s Workshop Saturday, May 6, 2005 9:00 AM at Camp Pioneer Barn/Riding Arena A morning of presentations on nutrition and horse health. Topics will include supplements and preventative care. I strongly encourage horse owners of all ages and experience to attend. Please RSVP to me at trwalker3@aol.com Non-Core Vaccines – These vaccines should be recommended on an individual case basis. Whether your horse should receive these vaccines, depends upon environment and use. For example, pregnant mares and show horses will frequently receive additional vaccinations. Symptoms Interval Effectiveness Rhinopneumonitis This disease is caused by a herpesvirus. EHV-1 is associated Pregnant mares should This vaccine is the most with abortion, neurologic disease, and respiratory disease. EHV- be boostered at 5,7, 9 & common culprit for 4 is generally restricted to respiratory infections. Horses are 11 months of gestation reactions that I have often infected with this at a young age and transiently shed it with a killed EHV-1 experienced. Some throughout life during periods of stress. This disease is vaccine. horses will get severe transmitted by aerosol and contact with tissue and placentas of localized swelling and aborted foals. Show horses and other muscle soreness at the horses that are in high vaccine site. It is There have been recent outbreaks of this neurologic form of this risk populations should important to note that the disease in race horses in Maryland and Kentucky. It is be vaccinated every 4- current EHV vaccines do interesting that these populations are among the most diligently 6 months with a killed not block infection, but vaccinated for this disease. This is prompting more research on EHV 1/4 or a modified rather decrease shedding the details of herpesvirus and how is lives in the body. There live EHV1. and potential infection of should be new vaccines and information surfacing in the next herdmates. None of the year. vaccines that are currently available are labeled to protect against the neurological disease. Potomac Horse This disease, occurring mostly from May to October, is caused Annual Booster This vaccine has Fever by a rickettsia that is found in certain streams and rivers. The This booster is most questionable life cycle of the infectious agent includes freshwater snails, a effective when given in effectiveness. It is not parasite within the snail, and flies along the riverbeds (including the Spring to maximize uncommon for vaccinated mayflies, dragonflies, caddisflies, and damselflies). Horses are immunity during the horses to develop disease. most likely infected from ingesting the adult flies or infected Summer season. However, there are no larvae in water sources or contaminated grazing areas next to specific adverse effects streams. Affected horses are severely depressed and develop Additional Booster from giving this vaccine. endotoxemia and profuse diarrhea. Many horses will die This is recommended regardless of treatment. However, some horses will survive with in July on farms that early diagnosis and aggressive treatment. have had confirmed cases of Potomac Horse Fever. Strangles This disease causes severe upper respiratory disease especially in Vaccination is The intranasal vaccine is young horses. Affected horses will have mild to profuse creamy generally only very effective but not nasal drainage and enlarged abscesses under the jaw and recommended in an without side effects. The throatlatch. Abscesses may spontaneously rupture and drain. It outbreak or if your intranasal vaccine is a is extremely contagious to other horses. Many horses will be horse is traveling to an modified live virus and infected and recover without major complications. However, area with a know should not be used in some horses will develop life threatening complications problem. Boosters pregnant mares. A severe including internal abscesses. should be given every potentially deadly six months. vascular complication of Vaccines are available as a modified live intranasal vaccine and purpura hemorhagica can a killed intramuscular vaccine. The IM vaccine can be occur. Severe localized given to mares 30 days swelling and pain has prior to foaling. been associated with the IM vaccine. Venezualan This is similar to the WEE & EEE included in the core vaccines. * Annual Booster This vaccine is very Encephalitis This occurs in Central and South America. An outbreak This booster is most effective. Reactions may occurrec most recently in Southern Mexico in 1993. However, effective when given in occur but are very rare. Venezualan encephalitis has not been diagnosed in the US for the Spring to maximize over 20 years. This vaccine is only recommended for horses immunity during the along states bordering Mexico. I do not routinely vaccinate for mosquito season. this disease. It is only recommended for those horses traveling to Texas and the Southwest for showing and training. There are many other vaccines available on the market for diseases such as botulism, rotavirus, anthrax and equine viral arteritis. Most of these are used on broodmare farms. In addition, vaccines are often sold in a combination as a “4-way”. Remember, that not all “4-way” vaccines protect against the same diseases. The standard 4-way vaccine that I use includes WEE, EEE, tetanus and flu. And, just because a vaccine is sold as a “5-way” or “7-way” etc. does not mean that it is the best vaccine for your horse. Vaccines and recommendations are constantly changing as new diseases emerge and we learn more about existing diseases. I am constantly updating my recommendations as new information becomes available. I am happy to customize a vaccine protocol for your horse’s specific needs. Internet Rumors & Recalls……..Sorting out the truth. The internet is a easily accessible resource for an unlimited amount of information. However, you must carefully consider the source, author and sponsor of any given website. I wanted to clarify a few of the recent rumors that several of you have asked me about. 1. Bimectin, a generic Ivermectin paste from Country Supply, killed a barn full of horses out West. False. This did not happen and represents the epitome of internet rumor. The story varies from a ranch to an Andalusian barn. The original email surfaced in October 2005. The lot number in question (5J019) was tested by the company and no contaminants, impurities or inconsistencies with the labeled dose and concentration were found. This product is an FDA approved product, which means that it has been tested and approved for safety and effectiveness. True reactions to the product would be immediately reported to the FDA and information disseminated appropriately. For more information you can read the press releases from the manufacturer at www.bimeda.com. Still doubting…..ask Sonya Penson. She just dewormed 13 horses with Bimectin with no ill effects. 2. West Nile Vaccine caused abortions in mares. False This rumor originated from a poorly researched article published in the Denver newspaper. The article claimed that an owner vaccinated his horses with West Nile Vaccine and they all aborted. This was a big discussion at the national equine vet conference this past December. No official reports of vaccine reactions were ever filed with the company or the FDA and all claims from the Denver article remain unsubstantiated. This vaccine is not yet labeled for use in pregnant mares but studies have shown no detrimental effects when used on pregnant mares. Regardless, no pregnant mare should ever be vaccinated in the first 60 days of pregnancy. Just as in people, this is a very fragile period for the fetus. During the first 60 days of pregnancy, even stress such as a fever or simple cold can cause abortion. 3. Diamond Pet Food is contaminated and will cause liver failure and death in dogs. True Sadly, this is true. I was first notified of this recall in early December. Several batches of dog food from this manufacturer were contaminated with aflatoxin. This toxin causes irreversible liver damage in dogs which eventually progresses to death. Food from contaminated batches was known to be delivered to many states on the East coast, including West Virginia. The manufacturer has been very aggressive in its attempt to notify the public of this hazard. Information has been circulated through television, national news, local news, veterinary organizations and retailers. For more information on this recall and the exact brand names of food involved, go to the recall website at www.diamondpetrecall.net. If you believe that your dog has eaten this food, blood tests can confirm whether or not there has been damage to the liver. Rest assured that in the event of a legitimate product recall, I will post information on the website (www.alleghenyequine.com) and in this newsletter. Tracy Walker, DVM Route 1 Box 115 Elkins, WV 26241