1st LINK-AGE / ESAAM Conference
on
Longevity, Ageing and Its Diseases
EUROPEAN SOCIETY OF
PREVENTIVE, REGENERATIVE
AND ANTI-AGING MEDICINE
21 - 23 June 2007
in
Dessau, Germany
Venue: Federal Administration of Environment (Umweltbundesamt)
Wörlitzer Platz 1, 06844 Dessau
FINAL PROGRAMME
Thursday, June 21, 2007
09.30 - 11.00
General Assembly of ESAAM (European Society of Preventive,
Regenerative and Anti-Aging Medicine)
11.30 - 12.30
Registration
12.30 - 13.00
Opening Remarks
13.00 - 14.00
Keynote Lectures
Chairpersons:
Environment and aging
A. Troge
President, Federal Administration of Environment, Dessau, Germany
Aging and neurodegenerative disorders
J. Schröder
Director, Department of Psychological Aging Research, Institute of
Psychology, University of Heidelberg, Heidelberg, Germany
14.00 - 16.00
Neurodegeneration
Chairpersons:
Two cohort studies in England and Wales
C. Brayne on behalf of CC75C and MRC CFAS
Department of Public Health & Primary Care, University of Cambridge,
Cambridge, England
Mitochondrial function in neurodegenerative disorders
M. Baron, A.P. Kudin, W.S. Kunz
Department of Epileptology and Life & Brain Center, University of Bonn,
Bonn, Germany
Gene expression analysis of Alzheimer’s dementia
K. Vogel1, C.L. Master2, T. Dyrks3
1
Departments of Dermatology, Venereology, Allergology and Immunology,
Dessau Medical Center, Dessau, Germany; 2Department of Pathology,
University of Melbourne, Victoria 3010,Australia; 3Bayer Schering Pharma
AG, Molecular Imaging Research, Berlin, Germany
Association of neurodegenerative diseases with hormonal aging
E. Makrantonaki1,2, J. Adjaye3, R. Herwig3, B. Hermes2, T.C. Brink3, H.
Lehrach3, C.C. Zouboulis1,2
1
Departments of Dermatology, Venereology, Allergology and Immunology,
Dessau Medical Center, Dessau, Germany; 2Laboratory for Biogerontology,
Dermato-Pharmacology and Dermato-Endocrinology, Institute of Clinical
Pharmacology and Toxicology, Charité Universitaetsmedizin Berlin, Berlin,
Germany; 3Department of Vertebrate Genomics, Max Planck Institute for
Molecular Genetics, Berlin, Germany
Effect of methamphetamine on protein oxidation in rat brain
hippocampus
P. Melo, A. Magalhães, M.A. Tavares, P. Moradas-Ferreira
IBMC-Instituto de Biologia Molecular e Celular, Faculdade de Medicina,
ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do
Porto, Porto, Portugal
Redox regulation of heat shock protein expression in aging and
neurodegenerative disorders: Role of vitagenes
V. Calabrese, C. Cornelius, S. Calafato
Department. of Chemistry, University of Catania, Catania, Italy
16.00 - 16.30
Coffee break and discussion
16.30 - 18.00
Regenerative Medicine
Chairpersons:
Stem cell aging and regenerative medicine
G. Lepperdinger
Austrian Academy of Sciences, Institute for Biomedical Aging Research,
Innsbruck, Austria
Mesenchymal stem cell aging
R. Brunauer1, C. Fehrer1, G. Laschober1, S. Reitinger1, F. Kloss2, R.
Gaßner2, G. Lepperdinger1
1
Extracellular Matrix Research, Institute for Biomedical Aging Research,
Austrian Academy of Sciences, Innsbruck, Austria; 2Department of Oral
and Maxillofacial Surgery, Medical University Innsbruck, Austria
Proteomics, PET and early detection of prostate cancer
M. Klentze1, H. Mischnik2
1
Klentze-Institutes of Preventive and Anti-Aging Medicine, Munich,
Germany; 2Mosaiques Diagnostics and Therapeutics AG, Hannover,
Germany
Biological age-parameters as predictors for health and disease
A.S. Wolf, G. Wolf, F. Wolf
Christian-Lauritzen Institute, Ulm, Germany
The Italian model of anabiotic medicine: 4-steps program
sensibilisation-assessment-strategy-health management
F. Marotta1, D. Galimberti2, F. Padrini1, I. Marandola1, F. Fayet1-3 , A.
Lorenzetti1, P. Marandola1
1
G.A.I.A. Age-Management Foundation, Pavia, Italy; 2AMIA Italian
Association of Antiaging Medicine; 3School of Molecular & Microbial
Biosciences, Human Nutrition Department, University of Sydney, Australia
19.30 -22.30
Cultural programme
Romeo and Julia
Anhalt Theatre Dessau
Friday, June 22, 2007
09.00 - 10.00
Osteoporosis / Nuclear Receptors
Chairpersons:
The orphan nuclear receptor estrogen receptor-related receptor 
(ERR) is a regulator of bone mass
J.-M. Vanacker, C. Teyssier, O. Chassande
Institut de Génomique Fonctionnelle de Lyon, Lyon, France
Exo1 – A biomarker of hormonal aging?
B. Hermes1, E. Makrantonaki1,2, J. Adjaye3, C.C. Zouboulis1,2
1
Laboratory for Biogerontology, Dermato-Pharmacology and DermatoEndocrinology, Institute of Clinical Pharmacology and Toxicology, Charité
Universitaetsmedizin Berlin, Berlin, Germany; 2Departments of
Dermatology and Immunology, Dessau Medical Center, Dessau, Germany;
3
Department of Vertebrate Genomics, Max Planck Institute for Molecular
Genetics, Berlin, Germany
Stress-induced premature senescence (SIPS) and human ageing
O. Toussaint, F. Debacq-Chainiaux
Research Unit of Cellular Biology, Department of Biology, URBC,
University of Namur (FUNDP), Namur, Belgium
10.00 - 11.00
Vascular Ageing / Diabetes
Chairpersons:
Protein glycation: a protective mechanism against ischemia
reperfusion injury?
A. Simm, R. Scheubel, B. Schneider, R.-E. Silber, B. Bartling
Department of Cardiothoracic Surgery, Martin-Luther-University HalleWittenberg, Halle, Germany
Stree-induced senescence-related signaling in mammalian cells and
Caenorhabditis elegans
L.O. Klotz
Institut für umweltmedizinische Forschung (IUF), Heinrich-HeineUniversitaet Düsseldorf, Düsseldorf, Germany
Type 2 diabetes, telomeres and oxidative damage
D.A. Hughes1, M.J. Sampson2
1
Institute of Food Research, Norwich Research Park, Norwich, U.K.;
2
Norfolk & Norwich University Hospital NHS Trust, Norwich, U.K.
11.00 - 12.00
Coffee break and discussion
12.00 - 13.00
Keynote Lectures
Chairpersons:
Geropolis – the city of the aged
O. Akbar
Director, Foundation Bauhaus Dessau, Dessau, Germany
Preventive oncology
J. Huber
Director, Division of Gynaecologic Endocrinology, Department of
Gynaecology, University of Vienna, Vienna, Austria
13.00 - 15.00
Lunch
15.00 - 16.30
Nutrition and Ageing
Chairpersons:
Functional role for newly identified proteins in the mitochondria
J. Haendeler
Institut für umweltmedizinische Forschung (IUF), Heinrich-HeineUniversitaet Düsseldorf, Düsseldorf, Germany
Age-dependent and genotype-specific effects of zinc on gene
expression
D.J. Mazzatti1, M. Malavolta2, A.J. White3, R. Giacconi 2, L. Costarelli2, E.
Muti2, C. Cipriano2, E. Mocchegiani2, J.R. Powell1
1
Unilever Corporate Research, Sharnbrook, U.K.; 2Italian National
Research Centre on Ageing, Ancona, Italy; 3Unilever Measurement
Sciences, Sharnbrook, U.K.
Fatty acids are unspecific PPAR activators
S. Schagen1,2, R. Voegeli1, D. Imfeld1, T. Schreier1, L. Michalik 4, W.
Wahli4, C.C. Zouboulis3
1
Pentapharm, Research & Development, Basel, Switzerland; 2University of
Basel, Basel, Switzerland; 3Dessau Medical Center, Departments of
Dermatology, Venereology, Allergology and Immunology, Dessau,
Germany; 4Centre for Integrative Genomics, University Lausanne,
Switzerland
From genomics to clinical practice: The biotechnological platform
F. Marotta1, D. Galimberti2, F. Fayet1-3 , A. Lorenzetti1, P. Marandola1
1
G.A.I.A. Age-Management Foundation, Pavia, Italy; 2AMIA Italian
Association of Antiaging Medicine; 3School of Molecular & Microbial
Biosciences, Human Nutrition Department, University of Sydney, Australia
Food intolerance, chronic immune activation and aging
R.D. Deutsch
Alcat Europe, Berlin, Germany
19.00 -21.00
Social programme
A boat trip along the Elbe river
Saturday, June 23, 2007
09.00 - 11.00
Skin Ageing / Pharmacology
Chairpersons:
Large scale deletions of the mitochondrial DNA increase oxidative
stress and alter cellular function in fibroblasts
M. Majora, T. Maresh, P. Schröder, J. Krutmann
Institut für umweltmedizinische Forschung (IUF), Heinrich-HeineUniversitaet Düsseldorf, Düsseldorf, Germany
Infrared A radiation triggers retrograde mitochondrial signalling to
modulate gene expression
P. Schröder, C. Pohl, C. Marks, S. Bruhnke, C. Calles, J. Krutmann
Institut für umweltmedizinische Forschung (IUF), Heinrich-HeineUniversitaet Düsseldorf, Düsseldorf, Germany
In vitro effect of ultraviolet irradiation on isolated fibrillin microfibrils
R.E.B. Watson1, S.M. Reilly1,2, C.E.M. Griffiths1, N.K. Gibbs1, M.J. Sherratt2
1
Dermatological Sciences and 2Tissue Injury & Repair, Faculty of Medical &
Human Sciences, The University of Manchester, Manchester, U.K.
Differential expression of extracellular matrix molecules between
photo-exposed and photo-protected skin
T.G. Tzellos1, I. Klagas1, E. Papakonstantinou1, K. Vahtsevanos2, S.
Triaridis3, G. Koloutsos2, G. Karakiulakis1
1
Department of Pharmacology and 31st Academic Otorhinolaryngology
Department School of Medicine, Aristotle University,Thessaloniki, Greece;
2
Department of Oral and Maxillofacial Surgery, Theageneion Anticancer
Hospital, Thessaloniki, Greece
GRO-alpha: A potential marker for cancer and aging silenced by RNA
interference
S. Fimmel1, L. Devermann1, A. Hermann1, C.C. Zouboulis1,2
1
Research Group on Biogentology, Dermato-Pharmacology and DermatoEndocrinology, Institute of Clinical Pharmacology and Toxicolgy, Charité–
Universitaetsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany;
2
Departments of Dermatology, Venereology, Allergology and Immunology,
Dessau Medical Center, Dessau, Germany
Xenobiotics, aging and therapeutic strategies
F. Marotta1, D. Galimberti2, F. Fayet1-3 , A. Lorenzetti1, P. Marandola1
1
G.A.I.A. Age-Management Foundation, Pavia, Italy; 2AMIA Italian
Association of Antiaging Medicine; 3School of Molecular & Microbial
Biosciences, Human Nutrition Department, University of Sydney, Australia
11.00 - 12.00
Coffee break and discussion
12.00 - 13.00
Keynote lectures
Chairpersons:
RANK ligand and osteoprotegerin in skeletal and vascular ageing
L.C. Hofbauer
Division of Endocrinology, Diabetes, and Bone Diseases, Department of
Medicine, Technical University of drsden, Dresden, Germany
Healthy ageing; from mechanisms to practice
J.R. Powell
Unilever Corporate Research, Colworth Park, Sharnbrook, Beds, U.K.
http://www.aging-congress.de