MUSÉUM NATIONAL D’HISTOIRE NATURELLE
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
1st Meeting of the
Groupement de Recherche International
PhyGHA
Physiology and Genetics of Healthy Aging
Paris 12 November 2014
Auditorium Grand Galerie de l’Evolution –MNHN
36 rue Geoffroy Saint-Hilaire - 75005 Paris
PRELIMINARY PROGRAM
PRELIMINARY PROGRAM
10.00 - 10.10 Entrance to the Grand Galerie de l’Evolution – MNHN
Talk should be of 10 min followed by 2 min questions
10.10 -10.20 Introduction by Giovanni LEVI, CNRS France - Presentation of the PhyGHA
Groupement de Recherche International
10.20 - 10.32 Claudio FRANCESCHI, University of Bologna, Italy - General overview of
the aims and main results of the EU consortium GEHA - Genetics of Healthy Aging
10.32 - 10.45 Eline SLAGBOOM - General overview of the aims and main results of the EU
consortium IDEAL – Integrated research on Developmental Determinants of Aging and
Longevity
Session I – Recent results and views on genetic factors of healthy aging
10.45 – 10.57 Paolo GARAGNANI, University of Bologna, Italy - The three genetics of
ageing
10.57 -11.09 Bezrukov VLADYSLAV - Genetic and epigenetic markers of the age-related
pathology (Alzheimer, Parkinson disease and metabolic syndrome)
11.09 -11.21 Maria Antonietta STAZI - Atherosclerosis as aging tract: the role of twin
studies.
11.21 -11.33 Michel POULAIN and Anne HERM - Updating the survival of Belgian GEHA
siblings
11.33 – 11.45 Irene Maeve REA - Living Long and Ageing Well : Insights From GeHA
European Nonagenarian Siblings - Dr Maeve Rea and GeHA consortium
11.45 – 11.57 Jean-Marie ROBINE - 5-COOP: The 5-Country Oldest-Old Project
11.57 – 12.09 Lars BOLUND - Research in China on the Genetics of Healthy Aging
12.09 – 12.22 Lene CHRISTIANSEN - Danish studies of twins and the oldest-old
12.30 - 14.00 Lunch at the Mosque (near to the GGE) and free discussion
Session II –Views on the physiology of healthy aging
14.10 – 14.22 Efstathios GONOS - Proteasome activation as a novel anti-ageing strategy
14.22 -14.34 Stefano SALVIOLI, University of Bologna, Italy - Circulating mtDNA in
healthy aging: implications for inflammaging
14.34 – 14.46 Giuseppe PASSARINO - Mitochondria and Aging: An integrative view of
genetic and epigenetic components.
14.46 – 14.58 Laurent SACHS - Cross talk between thyroid hormone and glucocorticoid
during post-embryonnic development: implication for DNA methylation.
14.58 – 15.10 Jean-Francois RIOU - Telomere biology of grey mouse lemur during aging
15.10 – 15.22 Irene Maeve REA - Mitochondrial J haplogroup is associated with lower
blood pressure and anti-oxidant status: findings in octo/nonagenarians from the BELFAST
Study
15.22 – 15.34 Angelo PARINI - Senescence of cardiomyocytes and cardiac stroma cells:
impact on heart failure
15.35 – 16.00 Coffee break
16.00 – 16.12 Bertrand FRIGUET - The aged proteome - impact of protein oxidative
modifications and maintenance in cellular aging
16.12 – 16.24 Barbara DEMENEIX - Switchbox : Brain-body homeostasis and ageing
16.24 – 16.36 Christian NERI and Jean MARIANI - The DHU ( University-Hospital
Department) FAST: Fight Ageing and Stress
16.40 - 18.00 General discussion:
« New concepts on aging: where are we going from here? »
20.30 Dinner offered by PhyGHA