Department of Clinical Immunology Wroclaw Medical University ul. Chałubińskiego 5, 50-368 Wrocław tel.: 71 784 17 40, faks: 71 784 04 17 e-mail: agnieszka.czerniawska@umed.wroc.pl Head: prof. dr hab. Marek Jutel IMMUNOLOGY Course information AY 2014/2015 Educational results for a student: Knows the basics of the immune system development and functioning, in particular mechanisms of specific and nonspecific humoral and cellular immune response. Describes the development and the role of individual components of the immune system. Clarifies the regulation of the immune response. Characterizes the specific and non-specific mechanisms of humoral and cellular immunity. Describes the major histocompatibility complex. Explains the role and mechanism of action of the major histocompatibility complex. Knows the types of hypersensitivity reactions, immune deficiencies as well as basics of the immune modulation. Characterizes various types of hypersensitivity reactions and explains the pathomechanisms of diseases of hypersensitivity. Describes the pathogenesis of primary and secondary immunodeficiencies. Explains the mechanisms of immunomodulation. Knows the issues of the neoplasm immunity. Characterizes by basic concepts of tumor immunology. Describes the genetic background of the transplant donor and recipient selection as well as the basics of the transplant immunity. Describes the basic concepts of transplant immunology and explains the basis for the selection of the donor and recipient. Knows the basic directions of the therapy development, in particular the cell therapy, gene therapy and targeted therapy in different diseases. Clarifies the regulation of the immune response in allergic diseases, autoimmune and proliferative diseases of the immune system. Characterizes different forms of immunotherapy. Applies the antigen-antibody reactions in current modifications and tests for the diagnostics of infectious, allergic, autoimmune, hematology and neoplastic diseases. Selects appropriate diagnostic methods for the detection of immunodeficiency, allergic diseases, autoimmune and proliferative diseases of the immune system. Relates the tissue and organ damage to the clinical symptoms of the disease, anamnesis and laboratory tests. Differentiate symptoms of immunocompromise. Correctly interprets the results of diagnostic studies evaluating the immune system. Analyses the processes of reaction, defense and adaptation as well as disturbances of the regulation in response to an etiologic factor. Properly analyzes clinical cases concerning disturbances in the immune system. 1 Department of Clinical Immunology Wroclaw Medical University ul. Chałubińskiego 5, 50-368 Wrocław tel.: 71 784 17 40, faks: 71 784 04 17 e-mail: agnieszka.czerniawska@umed.wroc.pl Head: prof. dr hab. Marek Jutel IMMUNOLOGY Course information AY 2014/2015 The Immunology course schedule Spring semester Lectures Classes Seminars hours 20 44 6 meetings 11 12 2 Total 70 11 + 14 Primary and secondary sources 1. Immunology, 8th Edition, Elsevier, 2013 Authors: David Male, Jonathan Brostoff, David Roth & Ivan Roitt 2. K. Abbas, A. H. Lichtman, S. Pillai : „Cellular and Molecular Immunology”, 6th Edition, Elsevier, 2012. 3. Peakman M., Vergani D.: “Basic and Clinical Immunology”. Second edition. Elsevier – Churchill Livingstone, 2009 ****************************************************************** 4. K. Abbas, A. H. Lichtman, S. Pillai : „Basic Immunology. Functions and disorders of the immune system”. Elsevier Saunders, 2011. 5. Allergy: European Journal of Allergy and Clinical Immunology. Wiley Blackwell 6. Journal of Allergy and Clinical Immunology. Elsevier. 7. Nature Reviews. Immunology. Nature New York, London Conditions for completing the course: Correct oral answers during classes, properly done practical exercises, credited partial colloquia, credited oral presentation during the seminar entitle to take the final credit colloquium. The student gained knowledge is verified with the final credit colloquium note a test of 30 questions with single choice option; threshold for credit - over 60% of correct answers. Positive completion of all forms of activities as well as the final colloquium enables the approach to the theory final exam: a written test, 60 questions with single choice option. Person responsible for the course: Prof. Marek Jutel, MD Person supervising the didactic issues for English Division students: Katarzyna Solarewicz-Madejek, MD, PhD e-mail: katarzyna.solarewicz-madejek@umed.wroc.pl Tel. +48717841742 2