PUBLICATIONS
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Rogers GB and Bruce KD Exploring the parallel development of microbial systems in cystic
fibrosis neonates – a commentary. Mbio (in press)
Wiriyachaiporn S, Howarth P, Bruce KD, Dailey LA Clinical evaluation of a rapid lateral flow
immunoassay for Staphylococcus aureus detection in respiratory samples Diagnostic
Microbiology and Infectious Disease (in press)
Rogers GB, Hoffman LR, Cutherbertson L, Wing P, Pope C, Hooftman D, Lilley AK, Carroll
MP, Bruce KD, van der Gast CJ. Towards unbiased bacterial community analysis in lower
respiratory infections. ISME J. (in press)
Chung J, Becq J, Fraser L, Schulz-Trieglaff O, Bond N, Foweraker J, Bruce K, Smith G, Welch
M (2012) Genomic variation among contemporary Pseudomonas aeruginosa isolates from
chronically-infected cystic fibrosis patients. Journal of Bacteriology 194:4857-4866.
Stressmann FA, Rogers GB, van der Gast CJ, Marsh P, Vermeer LS, Carroll MP, Hoffman LR,
Daniels TWV, Patel N, Forbes B, Bruce KD (2012) Long-term cultivation-independent
microbial diversity analysis demonstrates that bacterial communities infecting the cystic
fibrosis lung are stable and resilient. Thorax 67: 867-873 with an editorial by John LiPuma also
in the same issue.
Daniels TWV, Rogers GB, Stressmann FA, van der Gast CJ, Bruce KD, Jones G, Connett G,
Legg J, Carroll MP. Impact of antibiotic treatment for pulmonary exacerbations on bacterial
diversity in cystic fibrosis. Journal of Cystic Fibrosis (in press)
Fernandes ES, Liang L, Smillie SJ, Kaiser F, Purcell R, Rivett DW, Alam S, Howat S, Collins
H, Thompson SJ, Keeble JE, Riffo-Vasquez Y, Bruce KD, Brain SD (2012) TRPV1 deletion
enhances local inflammation and accelerates the onset of Systemic Inflammatory Response
Syndrome. Journal of Immunology 188: 5741-5751.
Payne MS, Goss KCW, Connett GJ, Legg JP, Bruce KD, Chalker V (2012) A quantitative
analysis of Ureaplasma urealyticum and Ureaplasma parvum compared with host immune
response in preterm neonates at risk of developing bronchopulmonary dysplasia. Journal of
Clinical Microbiology 50: 909- 914.
Rogers GB, Carroll MP, Bruce KD (2012) Enhancing the utility of existing antibiotics by
targeting bacterial behaviour? British Journal of Pharmacology 165: 845-85.
Stressmann, FA, Rogers GB, Marsh P, Lilley AK, Daniels TWV, Carroll MP, Hoffman LR,
Jones G, Allen CE, Patel N, Forbes B, Tuck A, Bruce KD (2011) Does bacterial density in
cystic fibrosis sputum increase prior to pulmonary exacerbation? Journal of Cystic Fibrosis 10:
357-365
Bruce KD, Rogers GB, Patel N (2011) Microbiological insights into respiratory infections and
the opportunities for inhaled therapy Journal of Drug Delivery Science and Technology 21:
301-309.
Stressmann FA, Rogers GB, Chan SW, Howarth PH, Harries PG, Bruce KD, Salib RJ (2011)
Characterization of bacterial community diversity in chronic rhinosinusitis infections using
novel culture-independent techniques. American Journal of Rhinology & Allergy 25:133-140
van der Gast CJ, Walker AW, Stressmann FA, Rogers GB, Scott P, Daniels TW, Carroll MP,
Parkhill J, Bruce KD (2011) Partitioning core and satellite taxa from within cystic fibrosis lung
bacterial communities ISME J 5: 780-791.
Junkes C, Harvey RD, Bruce KD, Doelling R, Bagheri M, Dathe M (2011) Cyclic
antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner
membranes in activity and the mode of action. European Biophysics Journal with Biophysics
Letters 40: 515- 528
Rogers GB, Hoffman LR, Johnson MW, Mayer-Hamblett N, Schwarze J, Carroll MP, Bruce
KD (2011) Using bacterial biomarkers to identify early indicators of cystic fibrosis pulmonary
exacerbation onset. Expert Review of Molecular Diagnostics 11: 197-206
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Stressmann FA, Rogers GB, Klem ER, Lilley AK, Wolfgang MC, Donaldson SH, Daniels T,
Carroll MP, Boucher RC, Bruce KD (2011) Analysis of the bacterial communities present in the
lungs of cystic fibrosis patients from American and British centers. Journal of Clinical
Microbiology 49:281-291.
Rogers GB, Marsh P, Stressmann AF, Allen CE, Daniels TV, Carroll MP, Bruce KD (2010)
The exclusion of dead bacterial cells is essential for accurate molecular analysis of clinical
samples. Clinical Microbiology and Infection 16:1656-1658.
Rogers GB, Bruce KD. Next-generation sequencing in the analysis of human microbiota:
essential considerations for clinical application. Molecular Diagnostics and Therapy 14:34350.
Slater FR, Bruce KD, Ellis RJ, Lilley AK, Turner SL (2010) Determining the effects of a
spatially heterogeneous selection pressure on bacterial population structure at the submillimetre scale. Microbial Ecology 60:873-84.
Rogers GB, Hoffman LR, Whiteley M, Daniels TW, Carroll MP, Bruce KD (2010) Revealing
the dynamics of polymicrobial infections. Trends in Microbiology 18:357-64.
Rogers GB, Fine D, Walker AW, Daniels TW, Carroll MP, Hoffman LR, Bruce KD (2010)
Insights obtained by contrasting the microbiota of the human lung and gut. Gut Microbes 1:8593.
Rogers GB, Russell LE, Preston PG, Marsh P, Collins JE, Saunders J, Sutton J, Fine D, Bruce
KD, Wright M (2010) Characterisation of bacteria in ascites--reporting the potential of cultureindependent, molecular analysis. European Journal of Clinical Microbiology and Infectious
Diseases. 29:533-41.
Rogers GB, Stressmann FA, Walker AW, Carroll MP, Bruce KD (2010) Lung infections in
cystic fibrosis: deriving clinical insight from microbial complexity. Expert Reviews of
Molecular Diagnostics 10:187-96.
Stressmann FA, Connett GJ, Goss K, Kollamparambil TG, Patel M, Payne MS, Puddy V, Legg
J, Bruce KD, Rogers GB (2010) Using culture-independent tools to characterise the bacteria
in endo-tracheal aspirates from pre-term infants at risk of BPD Journal of Perinatal Medicine.
38:333-7.
Spasenovski T, Carroll MP, Lilley AK, Bruce KD (2010) Modelling the bacterial communities
associated with cystic fibrosis lung infections European Journal of Clinical Microbiology and
Infectious Diseases 29:319-28.
Rogers GB, Skelton SP, Serisier D, van der Gast CJ, Bruce KD (2010) Determining CF lung
microbiology: a comparison of spontaneous and serially induced sputum samples using TRFLP profiling. Journal of Clinical Microbiology 48:78-86.
Payne MS, Goss KC, Connett GJ, Kollamparambil T, Legg JP, Thwaites R, Ashton M,
PuddyV, Bruce KD (2010) Molecular microbiological characterization of pre-term neonates at
risk of Bronchopulmonary Dysplasia Pediatric Research 67:412-8.
Johnson MW, Rogers GB, Bruce KD, Lilley AK, von Herbay A, Forbes A, Ciclitira PJ,
Nicholls RJ. (2009) Bacterial community diversity in cultures derived from healthy and
inflamed ileal pouches after restorative proctocolectomy. Inflammatory Bowel Disease
15:1803-1811.
Rogers GB, Carroll MP, Bruce KD (2009) Studying bacterial infections through cultureindependent approaches. Journal of Medical Microbiology 58:1401-18.
Rogers GB, Daniels TW, Tuck A, Carroll MP, Connett GJ, David GJ, Bruce KD (2009)
Studying bacteria in respiratory specimens by using conventional and molecular
microbiological approaches. BMC Pulmonary Medicine 9:14
Spasenovski T, Carroll MP, Payne MS, Bruce KD (2009) Molecular analysis of diversity
within the genus Pseudomonas in the lungs of cystic fibrosis patients. Diagnostic Microbiology
and Infectious Disease 63:261-7.
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Rogers GB, Stressmann FA, Koller G, Daniels T, Carroll MP, Bruce KD. (2008) Assessing the
diagnostic importance of nonviable bacterial cells in respiratory infections. Diagnostic
Microbiology and Infectious Disease 62:133-41.
Slater FR, Bruce KD, Ellis RJ, Lilley AK, Turner SL (2008) Heterogeneous selection in a
spatially structured environment affects fitness tradeoffs of plasmid carriage in pseudomonads.
Applied and Environmental Microbiology 74:3189-97.
Demirkan I, Williams HF, Dhawi A, Carter SD, Winstanley C, Bruce KD, Hart CA (2006)
Characterization of a spirochaete isolated from a case of bovine digital dermatitis. Journal of
Applied Microbiology 101:948-55.
Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Kehagia V, Connett GJ, Bruce KD
(2006) Use of 16S rRNA gene profiling by terminal restriction fragment length polymorphism
analysis to compare bacterial communities in sputum and mouthwash samples from patients
with cystic fibrosis. Journal of Clinical Microbiology 44:2601-4.
Green GL, Brostoff J, Hudspith B, Michael M, Mylonaki M, Rayment N, Staines N, Sanderson
J, Rampton DS, Bruce KD (2006) Molecular characterization of the bacteria adherent to human
colorectal mucosa. Journal of Applied Microbiology 100:460-9.
Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Kehagia V, Jones GR, Bruce KD (2005)
Bacterial activity in cystic fibrosis lung infections. Respiratory Research 6:49.
Rogers GB, Carroll MP, Connett GJ, Serisier DJ, Hockey PM, Kehagia V, Jones GR, Bruce
KD (2005). Bacterial community diversity in the CF lung. Pediatric Pulmonology 40, S28 pp
1-62.
Rogers GB, Carroll MP, Serisier DJ, Hockey PM, Jones G, Bruce KD (2004) Characterization
of bacterial community diversity in cystic fibrosis lung infections by use of 16S ribosomal
DNA terminal restriction fragment length polymorphism profiling. Journal of Clinical
Microbiology 42:5176-83.
Rogers GB, Hart CA, Mason JR, Hughes M, Walshaw MJ, Bruce KD (2003). Bacterial
diversity in cases of lung infection in cystic fibrosis patients: 16S ribosomal DNA (rDNA)
length heterogeneity PCR and 16S rDNA terminal restriction fragment length polymorphism
profiling. Journal of Clinical Microbiology 41:3548-58
Bruce KD, Hughes MR (2000) Terminal restriction fragment length polymorphism monitoring
of genes amplified directly from bacterial communities in soils and sediments. Molecular
Biotechnology 16:261-9.
Kandeler E, Tscherko D, Bruce KD, Stemmer M, Hobbs PJ, Bardgett RD, and Amelung W
(2000) Structure and function of the soil microbial community in microhabitats of a heavy
metal polluted soil. Biology and Fertility of Soils 32: 390-400.
Bruce KD, Jones TH, Bezemer TM, Thompson LJ, and Ritchie DA (2000) Effect of elevated
carbon dioxide levels on bacterial communities in model terrestrial ecosystems. Global Change
Biology 6: 427-434.
Holt RJ, Bruce KD, and Strike P (1999) Conservation of transposon structures in soil bacteria.
FEMS Microbiology Ecology 30: 25-37.
Jones TH, Thompson LJ, Lawton JH, Bezemer TM, Bardgett RD, Blackburn TM, Bruce KD,
Cannon PF, Hall GS, Hartley SE, Howson G, Jones CG, Kampichler C, Kandeler E, Ritchie
DA (1998) Impacts of rising atmospheric carbon dioxide on model terrestrial ecosystems.
Science 280:441-3.
Bruce KD (1997) Analysis of mer Gene Subclasses within Bacterial Communities in Soils and
Sediments Resolved by Fluorescent-PCR-Restriction Fragment Length Polymorphism
Profiling. Applied and Environmental Microbiology 63:4914-4919.
Osborn AM, Bruce KD, Strike P, Ritchie DA (1997) Distribution, diversity and evolution of
the bacterial mercury resistance (mer) operon. FEMS Microbiology Reviews 19:239-62.
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Viegas CA, Lilley AK, Bruce K, and Bailey MJ (1997) Description of a novel plasmid
replicative origin from a genetically distinct family of conjugative plasmids associated with
phytosphere microflora. FEMS Microbiology Letters 149: 121-127.
Holt RJ, Strike P, Bruce KD (1996) Phylogenetic analysis of tnpR genes in mercury resistant
soil bacteria: the relationship between DNA sequencing and RFLP typing approaches. FEMS
Microbiol Letters 144:95-102.
Pearson AJ, Bruce KD, Osborn AM, Ritchie DA, Strike P (1996) Distribution of class II
transposase and resolvase genes in soil bacteria and their association with mer genes. Applied
and Environmental Microbiology 62:2961-5.
Osborn AM, Bruce KD, Ritchie DA, Strike P (1996) The mercury resistance operon of the IncJ
plasmid pMERPH exhibits structural and regulatory divergence from other Gram-negative
mer operons. Microbiology. 142:337-45.
Safarnejad A, Collin HA, Bruce KD, and McNeilly T (1996) Characterization of alfalfa
(Medicago sativa L.) following in vitro selection for salt tolerance. Euphytica. 92: 55-61.
Osborn AM, Bruce KD, Strike P, and Ritchie DA (1995) Sequence conservation between
regulatory mercury resistance genes in bacteria from mercury polluted and pristine
environments. Systematic and Applied Microbiology 18: 1-6.
Bruce KD, Osborn AM, Pearson AJ, Strike P, Ritchie DA (1995) Genetic diversity within mer
genes directly amplified from communities of noncultivated soil and sediment bacteria.
Molecular Ecology 4:605-12.
Cash P, Argo E, Bruce KD (1995) Characterisation of Haemophilus influenzae proteins by
two-dimensional gel electrophoresis. Electrophoresis. 16:135-48.
Osborn AM, Bruce KD, Strike P, Ritchie DA (1993) Polymerase chain reaction-restriction
fragment length polymorphism analysis shows divergence among mer determinants from
gram-negative soil bacteria indistinguishable by DNA-DNA hybridization. Applied and
Environmental Microbiology 59:4024-30.
Bruce KD, Hiorns WD, Hobman JL, Osborn AM, Strike P, Ritchie DA (1992) Amplification
of DNA from native populations of soil bacteria by using the polymerase chain reaction.
Applied and Environmental Microbiology 58:3413-6.
Forbes KJ, Bruce KD, Ball A, Pennington TH (1992) Variation in length and sequence of porin
(ompP2) alleles of non-capsulate Haemophilus influenzae. Molecular Microbiology 6:2107-12.
Forbes KJ, Bruce KD, Jordens JZ, Ball A, Pennington TH (1991) Rapid methods in bacterial
DNA fingerprinting. Journal of General Microbiology. 137:2051-8.
Bruce KD, Pennington TH (1991) Clonal analysis of non-typable Haemophilus influenzae by
sodium dodecyl sulphate-polyacrylamide gel electrophoresis of whole cell polypeptides.
Journal of Medical Microbiology. 34:277-83
Bruce KD, Jordens JZ (1991) Characterization of noncapsulate Haemophilus influenzae by
whole-cell polypeptide profiles, restriction endonuclease analysis, and rRNA gene restriction
patterns. Journal of Clinical Microbiology 29:291-6.