MARKET FOR PET RADIOPHAMACEUTICALS
AND PET IMAGING
TABLE OF CONTENTS
Section
1.0
2.0
Page
PET MARKET OVERVIEW
1
1.1
Changes in PET Reimbursement
3
1.2
National Oncologic PET Registry (NOPR)
5
1.3
Therapy Planning and Treatment Monitoring
6
1.4
PET Reimbursement for Alzheimer's Disease
7
1.5
Impact of PET-CT
8
1.6
Cardiology Applications of PET
9
1.7
Research in PET Tracers
10
1.8
Changes in Market Environment
12
1.9
Growth of Primary Applications for PET in Oncology
14
1.10
Overview of PET Scanner Sales
15
1.10.1 Impact of New Technology
17
1.10.2 Growth of Mobile PET
18
GROWTH IN PET PROCEDURE VOLUME
19
2.1
Expanded Reimbursement for PET
21
2.2
Distribution of PET Procedures
22
2.3
Oncology PET Procedures
24
2.4
Overlap Between PET and SPECT Imaging in Oncology
26
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TABLE OF CONTENTS
Section
Page
2.5
3.0
Experience with Targeted SPECT Agents for Oncology
27
2.4.2
Comparative Advantages of PET in Oncology
28
Clinical Requirements And Projections For PET
29
ANALYSIS OF THE FDG MARKET
30
3.1
Price Per Dose and Delivery Charges
31
3.2
Historic And Forecast Sales of FDG
32
3.2.1
Distribution of FDG Sales
34
3.2.2
Oncology Sales of FDG
35
3.2.3
Rubidium Sales for Cardiology PET
37
3.3
3.4
4.0
2.4.1
Analysis of FDG Suppliers
38
3.3.1
Economics of Producing and Delivering FDG Doses
38
3.3.2
Market Distribution of Commercial FDG Suppliers
41
3.3.2.1
PETNet Pharmaceuticals
41
3.3.2.2
Other Commercial Distributors Of FDG
43
Challenges In The Production and Distribution of FDG
46
MARKET FOR PET IMAGING EQUIPMENT
47
4.1
Market Overview
47
4.2
Product Focus of PET Manufacturers
55
4.2.1
Siemens Molecular Imaging
56
4.2.2
GE Medical Systems
58
4.2.3
Philips Medical Systems
60
4.2.4
Positron Corporation
62
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TABLE OF CONTENTS
Section
Page
4.3
4.4
5.0
6.0
7.0
US and Worldwide Distribution of PET Scanner Sales
63
4.3.1
Domestic Unit Sales of PET Scanners
64
4.3.2
Domestic Sales Volume Distribution
65
4.3.3
Worldwide Sales Distribution of PET scanners
66
Mobile PET Sales
67
4.4.1
Prospects for Mobile PET
68
4.4.2
Providers of Mobile PET
70
4.4.3
Reimbursement Issues and Factors Affecting Growth
72
US AND WORLDWIDE SALES FORECASTS FOR PET
74
5.1
US Sales Forecasts for PET Scanners
74
5.2
Combined PET-CT Systems
79
5.3
Sales of Mobile PET Systems
79
5.4
Worldwide Sales Forecast for PET Scanners
80
GROWTH OF US AND WORLDWIDE INSTALLED BASE
82
6.1
Growth of the Domestic installed Base
82
6.2
Growth of Installed Base of Mobile Scanners
82
6.3
Worldwide Installed Base of PET
85
6.4
Estimated PET Procedure Volume Based on Scanner Utilization
85
6.5
Comparison of PET and SPECT Installed Base
88
END-USER PROFILE
90
7.1
Overview of the User Environment
90
7.2
Organization of Nuclear Medicine Departments
91
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TABLE OF CONTENTS
Section
Page
7.2.1
Important Functional Differences with PET
92
7.2.2
Interaction of PET with Radiology
93
7.3
Allocation of Hospital Nuclear Medicine Equipment
94
7.4
Comparative Utilization Parameters
96
7.4.1
Distribution of Imaging Procedures
96
7.4.2
Relative Diagnostic Activity
98
7.4.3
Relative Procedure Volume
98
7.4.4
Imaging Activity Index
7.5
101
In-Hospital Hot Lab Versus Commercial Pharmacies
103
7.5.1
Unit-Dose Packaging
104
7.5.2
Pricing Practices
104
7.5.3
Other Services
105
7.5.4
Issues of Board Certification
106
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MARKET FOR PET RADIOPHAMACEUTICALS
AND PET IMAGING
LIST OF EXHIBITS
Exhibit
Page
1
HISTORIC AND FORECAST PET PROCEDURE VOLUME FOR
CARDIOLOGY, NEUROLOGY AND ONCOLOGY BY PROCEDURE
TYPE FROM 2002-2012
23
2
HISTORIC AND FORECAST PET PROCEDURE VOLUME IN ONCOLOGY
BY TYPE OF DISEASE FROM 2003-2012
25
3
HISTORIC AND FORECAST SALES OF FDG DOSES FOR CARDIOLOGY,
NEUROLOGY AND ONCOLOGY BY PROCEDURE TYPE
FROM 2002-2012
33
4
HISTORIC AND FORECAST SALES OF FDG FOR ONCOLOGY
APPLICATIONS BY DISEASE TYPE FROM 2002-2012
36
5
HISTORIC AND FORECAST SALES OF RUBIDIUM DOSES FOR
CADIOLOGY PET PERFUSION STUDIES FROM 2002-2012
39
6
2006 DISTRIBUTION OF COMMERCIAL FDG SUPPLIERS IN THE U.S.,
NUMBER OF END-USERS, ANNUAL DOSES SOLD AND SALES VOLUME
42
7
U.S. SALES OF PET SCANNERS FROM 2002-2005, MANUFACTURER’S
UNIT SALES AND MARKET SHARE
48
8
U.S. SALES OF PET SCANNERS FROM 2002-2005, MANUFACTURER'S
SALES DOLLAR VOLUME AND MARKET SHARE
49
9
WORLDWIDE SALES OF PET SCANNERS FROM 2002-2005,
MANUFACTURER’S UNIT SALES AND MARKET SHARE
50
10
WORLDWIDE SALES OF PET SCANNERS FROM 2002-2005,
MANUFACTURER’S SALES DOLLAR VOLUME AND MARKET SHARE
51
11
U.S. SALES OF MOBILE PET SCANNERS FROM 2002-2005,
MANUFACTURER’S UNIT SALES AND MARKET SHARE
52
12
U.S. SALES OF MOBILE PET SCANNERS FROM 2002-2005,
MANUFACTURER’S SALES DOLLAR VOLUME AND MARKET SHARE
53
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LIST OF EXHIBITS
Exhibit
Page
13
DISTRIBUTION OF MOBILE PET UNITS AMONG MOBILE PET
PROVIDERS, UNITS PURCHASED BY EACH MOBILE PET
COMPANY FROM 2000-2005
71
14
HISTORIC AND FORECAST U.S. UNIT SALES AND SALES DOLLAR
VOLUME OF PET SCANNERS FROM 2002-2012
75
15
HISTORIC AND FORECAST U.S. SALES OF MOBILE PET SCANNERS,
MANUFACTURER’S UNIT SHIPMENTS AND SALES VOLUME
FROM 2002-2012
76
16
HISTORIC AND FORECAST WORLDWIDE UNIT SALES AND SALES
DOLLAR VOLUME OF PET SCANNERS FROM 2002-2012
77
17
GROWTH OF U.S. INSTALLED BASE OF PET SCANNERS AND
CAMERA-BASED PET SYSTEMS FROM 2002-2012
83
18
GROWTH OF MOBILE PET INSTALLED BASE IN THE U.S
. FROM 2002-2012
84
19
GROWTH OF WORLDWIDE INSTALLED BASE OF PET SCANNERS AND
CAMERA-BASED PET SYSTEMS FROM 2002-2012
86
20
ESTIMATED PROCEDURE VOLUME BASED ON SCANNER
UTILIZATION IN 2005
87
21
2005 NUCLEAR CAMERA SHIPMENTS, INSTALLED BASE AND
REPLACEMENT RATES FOR NEW AND REFURBISHED CAMERAS IN
HOSPITALS AND IMAGING CLINICS
89
22
COMPARATIVE ALLOCATION OF DIAGNOSTIC FACILITIES
BY HOSPITAL BED SIZE IN 2005
95
23
COMPARATIVE UTILIZATION PARAMETERS FOR DIFFERENT IMAGING
MODALITIES IN 2005
97
24
DISTRIBUTION OF HOSPITAL DIAGNOSTIC IMAGING PROCEDURES
IN THE U.S. BY HOSPITAL BED SIZE IN 2005
99
25
RELATIVE PROCEDURE VOLUME AMONG DIFFERENT IMAGING
MODALITIES, PERCENTAGE RELATIONSHIP BY HOSPITAL BED SIZE
IN 2005
100
26
RELATIVE ACTIVITY INDEX AMONG DIFFERENT IMAGING MODALITIES, 102
PROCEDURES PER BED PER YEAR BY HOSPITAL BED SIZE IN 2005
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