CARRICKVETS.ie JUNE 2013 NEWSLETTER Carrick Veterinary Centre, Unit 11, Steadfast Industrial estate, Carrickmacross, Co. Monaghan. THE COUGHING COW. IBR virus causes pneumonia in adult cattle mainly but it can affect cattle of all ages. It usually presents as a high temperature, the animal may be dull and empty. Sometimes you may see white snots in the nose and you may hear roughness in the upper airways. The virus effects the upper airways so don’t be concentrating on finding a blow. A word of warning about IBR, once cattle are infected they become carriers for life and in times of stress the virus can be shed from the carriers infecting others. One case of IBR can affect 7 other cattle in an outbreak. Vaccination reduces shedding dramatically and were vaccinated cattle are exposed to IBR virus they have pre-formed antibodies which will kill the virus minimising clinical signs of the disease and minimising formation of the carrier state. BVD is important and widespread in Irish herds. Approximately 1% of cattle are persistently infected with the disease. These cattle will shed virus 24/7. In a www.carrickvets.ie confined area this virus will spread up the shed causing immuno-suppression and allowing other viruses like IBR to be shed more easily. The principal virus involved with dairy herd pneumonia is IBR. As I said earlier if you have dull cows going back in their milk with high temperatures. Suspect IBR. If you have white snots and coughing suspect IBR. IBR theoretically causes inflammation of the ovaries and fallopian tubes of the cow’s reproductive tract leading to embryo loss. It is difficult to quantify this problem. We can now measure the level of exposure to IBR in the milking herd through a bulk milk sample test. You should request a BVD virus bulk sample test when you are doing it. Nasal swabs are useful as the technology has improved in the labs. Rispoval IBR live and bovilis IBR live vaccine are given every 6 months. The vaccine is due now if you used the vaccine in December. It is due in July if you used it in January. There have been a significant number of dairy herds in Ireland which are presented from mid-summer right through the autumn as coughing. The cows may have white snots in their noses and there may be a significant drop in milk yields associated with it. Many vets felt it was IBR virus but nasal swabs failed to prove it. The current thinking is that these herds have lungworm infections. It is felt that these herds have failed to obtain full immunity to lungworm due to overuse of worming during the first and second grazing seasons. The lessened immunity allows the larvae to develop in the lung. The cow attacks the larvae Tel:042 9661384 with white blood cells and antibodies leading to inflamed lungs. The cow is presented as coughing with white snots present. There may be a noticeable drop in milk yields particularly in younger herds. Dung samples will not diagnose this problem as there is sufficient immunity in the cow to prevent adult lungworms developing in the adult cow which produce the larvae in the dung. The current thinking is dose your calves well in the first grazing season and then aim to give them 2 doses in the second grazing season to allow immunity to develop. Ironically the treatment for the coughing cows is dosing. Traditionally eprinex was given in May/June now there are generics of eprinex available. We are stocking Robonex pour on. This product is licensed for dairy cows and has no milk withdrawal. Giving Robonex pour on to the milking herd in June makes economic sense. There is a slight lift in milk yield in the herd which is sustained over a period of time. Research has demonstrated a slight reduction in herd calving intervals. The improvements are more noticeable in younger herds. We have a great introductory offer on Robonex. Robonex is priced well and offers real value for our customers. Eprinex has been reduced in price lately due to the loss in patent. 5 litres of eprinex pour on can be bought for €420. www.carrickvets.ie RUSTY COATS IN COWS AND CALVES. Stand back and look at your cattle. If they have dull rusty coats and are slow to loose their winter coats consider stress, worms, copper deficiency and in calves coccidiosis. The principal stress cattle have endured is a long hard winter with poor nutrition. Stomach worms cause ill-thrift. Last year was extremely wet and there are cattle with greater fluke burdens about also. I recommend closivet pour –on or closamectin injection in the second grazing season when cattle are 10 weeks out on grass. Copper should be given orally in the bolus form if cattle are not being fed meal. Copper injections raise lumps. Two boluses are given to cattle over 350kg. Copper boluses are ideal for cattle during the second grazing season particularly if these cattle are being grazed without concentrates. All trace boluses provide copper, selenium, iodine and cobalt for 6 months. They are beneficial to suckler farmers during the breeding season were meal is not being fed. Dairy calves can have subclinical coccidiosis. They have dung stuck around their tails, rusty coats, their eyes may appear dull. These calves can respond well to baycox for coccidiosis. Farmers may have treated calves at 3 weeks for coccidiosis with baycox or veccoxan. Most of the time Tel:042 9661384 this works but calves may require a second dose of baycox 45 days after the first treatment and 30 days for veccoxan. DOSING ADVICE. Cydectin LA injection is ideal for young calves during the first grazing season. It kills lungworm and stomach worms for 120 days. Cydectin LA will suit farmers who have poor handling facilities on out-farms. Calves can be treated once now and that will cover them the whole grazing season. Cydectin LA will suit farmers that are time poor during the summer such as those that have off farm jobs, silage contractors, fragmented farms etc. Cydectin LA is given subcut behind the ear. The dosage is 1 ml per 100 kg. It costs around €2.75 per calf weighing 100kg. Cydectin pour on or injection can be given at 10 week intervals in the first grazing season. Dectomax has returned as Zearl. Zearl works for 8 weeks killing lungworm and stomach worms. Cattle in their second grazing season need only to be dosed twice. Closivet pour on or closamectin injection is ideal now for second grazers. It contains ivomec as well as a flukacide which kills 2 out of 3 stages of fluke. It also has a residual killing effect on fluke it leaves behind. All in all fluke burdens are dramatically reduced in these cattle before the year end allowing these second grazers to thrive better on grass. FACE BOOK. Carrick vet centre has set up a face book page. It can be accessed through our website carrickvets.ie. It will be updated regularly giving advice, special offers and commenting on special cases. You can ‘like’ the site and in that way you will be notified when the face book page has been updated. SCHMALLENBERG TALK. I attended a talk on Schmallenberg virus in Mullingar recently. A summary of the talk is as follows. Schmallenberg virus was first isolated in the German village of Schmallenberg sometime in 2011. The virus affects cattle and sheep. It affects cattle in an acute and chronic form. Cattle with the acute form of the disease are presented with high temperatures, scour, inapetance and reduced milk yields for 2-7 days. The chronic form is presented as deformed calves at birth with bent and stiff necks, swollen and stiff joints. The calves are presented in a flexed position and may be difficult to calf. The calves may be born alive but will need to be euthanized. Calves may also be born with brain abnormalities. Part of the brain can be missing leading to dummy calves which cannot suck. Sheep only have the chronic form of the disease with deformed lambs. The virus does not kill the adult cattle or sheep. The disease is spread by infected midges. The midge season is www.carrickvets.ie Tel:042 9661384 April to November. The disease has moved gradually over Europe westwards towards Ireland. Last year it reached Irish shores. It primarily hit the south and east coast of Ireland. It hit Louth significantly and was found in 13% of cattle sampled for the disease in Co. Monaghan. The disease was not found in Co. Cavan. The virus affects pregnant cows between 40 and 140 days leading to deformed calves. Although it hit Co. Louth the cows I believe were mainly past 140 days in calf when the infected midges hit. The infected midges produced infected pupa which hibernated over the winter. These infected pupae have produced many infected midges this year. These midges are currently biting our cattle and sheep. The disease causes sporadic disease with some farmers being hit worse than others. The infected midges will be hitting cattle in the vulnerable period of 40-140 days this year. Once a cow is bitten by an infected midge it will develop immunity against the disease. The disease is new so we do not know if the immunity is life long or not. There were only 13% of cattle possibly bitten by infected midges in Co. Monaghan last year so there is a lot of naïve cattle which if bitten between 40-140 days in calf this year could have deformed calves in the spring of 2014. There is a vaccine now available it should have been given before the breeding season started but it has only been introduced lately. Sheep need only one shot and the vaccine is effective 2-3 weeks after the first shot. Cattle require 2 shots one month apart. The vaccine is effective 2-3 weeks after the second shot. The vaccine is possibly too late for spring www.carrickvets.ie calving. It is suitable for sheep and autumn calving this year. It will have limited affects in spring calvers. The vaccine will have a limited affect shortly after the first shot. Will it be enough to stop the effects of Schmallenberg virus this season in spring calving is difficult to say. The vaccine was reported to cost €3.30 a shot on the night. The disease has been reported to cause 2-5% foetal abnormalities on farms last year. This figure cannot be trusted farmers with problems are not always reporting it. When they figure out they have schmallenberg they may just get on with it and some are afraid of people talking. A lot is not known about the disease. Why it hits one farm hard and leaves it’s neighbours ok is difficult to figure out. Bio-security doesn’t work midges don’t respect boundaries. I don’t believe fly repellants may be that effective. Although the fly repellent will kill the midge after it bites. I think the infected midge will have already infected the cow or sheep with the virus. The disease may lead to foetal absorption increasing the number of empty cows and ewes at the end of the season. We have calved cows with deformed calves and taken blood samples for serology. Samples have come back positive to schmallenberg virus this was in March 2013. Turnout for the Mullingar talk was poor. The organisers have held them all over the country. In towns on Tel:042 9661384 the south coast and east coast were Schmallenberg virus hit turnout was huge. I believe there is a lot of complacency in Co. Monaghan with regard to this disease. The vaccine is available. We can get it for you within 24 hours. The vaccine is out under special licence and work is being carried out on the vaccine to check how long it works, safety issues etc. In my opinion the vaccine is too late for next year spring calvers. www.carrickvets.ie Tel:042 9661384 Schmallenberg virus. Carrick Veterinary Centre has diagnosed Schmallenberg locally. Diagnosis is based on a positive result from a blood elisa test and were there is a history of a deformed calf. An infected midge injects the virus into the host animal. If the cow is 20-80 days in calf, the virus affects the central nervous system leading to brain damage, many calves infected at this stage appear normal but are unable to suck. If the virus affects cows 80-160 Scooping and scanning. We are currently scooping and scanning spring calving herds prebreeding and during the early breeding period. We scoop cows to identify dirty cows. Tail paint the herd and return 25 days later and recheck the dirty cows and scan cows that have not removed the tail paint. We have a www.carrickvets.ie Tel:042 9661384 specific regime for treating ‘whites’, metritis, non-cycling cows, cystic cows and phantom cows. The aim of scooping, scanning and treatment is to maximise the number of clean and cycling cows at the start of the breeding season. All herds to some degree have a percentage of dirty and non-cycling cows at the start of the breeding season. Addressing these cows can have dramatic economic benefits for the herd. If you can reduce the calving interval of 100 cows by 5 days. It is worth €4,500 in positive cash flow. (100 cows x 5 days x 6 gallons x €1.50 a gallon). If you reduce the calving interval by a multiple of 5 days and reduce culling rate at the end of the year then you are making dramatic money. Teagasc advise a submission rate of 85% in the first 3 weeks of the breeding season. A pregnancy rate in the first 3 weeks of 55%. 100% of your cows should be submitted in the first 6 weeks of the breeding season and the overall conception rate of 75% aimed for in 6 weeks. Farmers in the past waited for cows to come into heat and then hoped for a good conception rate. It is better to actively promote a good submission rate by forcing problem cows to clean faster and cycle faster. Many times the conception rate to treated cows in the first 3 weeks can be disappointing but many of these cows go back in calf in the second cycle. WORMING STRATEGY. Worms require soil temperatures of +10 degrees celsius to www.carrickvets.ie become active on pastures. It is conceivable that cattle may not need to be dosed until 6 weeks after turnout due to the late spring. Pfizer has launched Cydectin L.A.. This injection is given at the back of the ear and will kill worms for 120 days. It may be beneficial to first grazers reared on out-farms. Norbrook has launched a generic of eprinex pour on. Robonex kills worms in dairy cows for 8 weeks and has no milk withdrawal. In the past dairy farmers have used eprinex in May. Due to the late spring June is more than adequate. Eprinex is still the qualified original. Generics such as eprizero and rabonex have different carriers than eprinex. Eprinex has the field work done whereas the generics have not. Dairy farmers tend to push thrive in first and second grazers so that they are fit for bulling at 2 years old. Many dairy farmers tend to overdose their calves in the first and second grazing season. This practice can prevent a strong immunity developing to lungworm in cattle. Consequently if adult cattle are exposed to lungworm their immune system is sensitised to the lungworm over-reacting flooding the lungs with antibody and white blood cells leading to the ‘coughing cow’ syndrome. There are a number of dairy farmers with a large number of dairy cows coughing in the summer. Many of these farmers think that it is an outbreak of IBR. Ironically the treatment is eprinex. Dairy farmers may need to take a simpler view to dosing. In the first grazing season they could dose with Tel:042 9661384 Ivomec Super at 3, 8 and 13 weeks after turnout. In the second grazing season give them two doses. Closamectin given at 8 weeks after turnout kills 2 stages out of 3 for fluke. Closamectin also has a residual killing effect therefore it still keeps killing and stunting fluke for weeks after it has been used. The overall effect is to reduce the fluke burden at the end of the year improving thrive throughout the grazing season. BAYCOX Coccidiosis is a disease of calves between 3 and 12 weeks of age. Clinical cases are presented with a blood scour and pining. Where one calf has coccidiosis you can be sure that there are many other comrade calves with sub-clinical disease. These calves are presented with dung caked to their tail region and slight ill-thrift. Calves with coccidiuosis tend to eat at bedding and lick walls. Monensin is an ionophore and promotes the population of bacteria which makes proprionic acid. Proprionic acid is the main driver of energy in dairy cows. Monensin makes best use of the feed that is available to dairy cows. We have data sheets for this product. I see kexxtone as a tool for high risk Holsteins such as first calf heifers, high yielding dairy cows, Holstein cows with a long dry period and cows with a previous history of metabolic disease. It could be used in 15% of the herd closing the energy gap which is naturally there in the first 75 days after calving and reducing energy deficits 3 weeks before calving. It is an exciting new idea. It has only been launched and may be used in autumn calving herds initially. Baycox reduces shedding of coccidia 50% longer than veccoxan. Baycox can be given to calves at 3 weeks of age but it is best given at the first signs of coccidiosis in calves. Baycox is given orally at 3ml per 10kg orally. INTRODUCING KEXXTONE. Elanco has launched a very interesting bolus called kexxtone. It consists of a drug that has been banned from Europe this last 30 years called monensin. Monensin familiar name to farmers was rumensin. www.carrickvets.ie Tel:042 9661384