BIOGRAPHICAL SKETCH NAME POSITION TITLE Pan, Hua Research Instructor in Medicine EDUCATION/TRAINING INSTITUTION AND LOCATION DEGREE (if applicable) Huazhong University of Science and Technology Huazhong University of Science and Technology Case Western Reserve University Washington University in St. Louis B.E. Master of Medicine M.S. Ph.D. YEAR(s) 1997 2000 2004 2007 FIELD OF STUDY Biomedical Engineering Biomedicine Biomedical Engineering Biomedical Engineering A. Positions and Honors. Positions and Employment 1997-2001 Instructor, Huazhong University of Science and Technology, China 2007-2010 Postdoctoral research associate, Washington University School of Medicine, St. Louis, MO 2011Research Instructor in Medicine, Washington University School of Medicine, St. Louis, MO Other Experiences 2002-2004 Mentor for Professional Development for International Graduate Teaching Assistants 2010 Mentor for the 2010 Young Scientist Summer Focus Research Program 2010 Judge for Opportunities in Genomics Research Undergraduate Scholars Program Professional Memberships 2010 – Current American Heart Association (AHA) 2003/04/07/09 Biophysical Society 2009 – Current The American Society for Cell Biology (ASCB) 2010 – Current The American Society for Pharmacology and Experimental Therapeutics (ASPET) Honors 1995-1996 2001-2004 Outstanding student awards Whitaker Fellow Trainee B. Selected peer-reviewed publications. Deng CX, Sieling F, Pan H, Cui J. Ultrasound induced cell-membrane porosity. Ultrasound Med. Biol 2004; 30:519-526 Pan H, Zhou Y, Izadnegahdar O, Cui J, Deng CX. Study of sonoporation dynamics affected by ultrasound duty cycle. Ultrasound Med Biol 2005; 31:849-856. Silva JR, Pan H, Wu D, Nekouzadeh A, Decker KF, Cui J, Baker NA, Sept D, Rudy Y, A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential. Proc Natl Acad Sci USA. 2009 Jul 7;106(27):11102-6. Hood JL, Pan H, Lanza GM, Wickline SA. Paracrine induction of endothelium by tumor exosomes. Lab Invest. 2009 Nov; 89(11):1317-28. Pan H, Myerson JW, Ivashyna O, Soman NR, Marsh JN, Hood JL, Lanza GM, Schlesinger PH, Wickline SA. Lipid membrane editing with peptide cargo linkers in cells and synthetic nanostructures. FASEB J. 2010 Aug;24(8):2928-37. (Cover article) Wu D., Pan H, Delaloye K, Cui J. KCNE1 remodels the voltage sensor of KV7.1 to modulate channel function. Biophys. J. 2010 Dec 1;99(11):3599-608. Pan H, Ivashyna O, Sinha B, Lanza GM, Ratner L, Schlesinger PH, Wickline SA. Post-formulation Peptide Drug Loading of Nanostructures for Metered Control of NF-κB Signaling. Biomaterials. 2011 Jan;32(1):231-238. Pan H, Soman NR, Schlesinger PH, Lanza GM, Wickline SA. Cytolytic Peptide Nanoparticles (“NanoBees”) for cancer therapy. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011 Jan 10. C. Patent Peptide Linker For Drug Delivery and/or Site-Specific Targeting: Hua Pan et al (WO 2009/151788A2) D. Research Support Ongoing Research Support Pilot Grant St. Louis Institute of Nanomedicine 01/01/2010-12/31/2010; Total Award $36,000 Development of nanoparticle multiplexing strategy for rapid clinic translation. Principal Investigator: Hua Pan