Papers for presentations
Name of
students
Date of
presentation
Name of paper
Comments
A silent polymorphism in the MDR1 gene changes
substrate specificity; Kimchi-Sarfaty et al. (2007)
Science 315, 525-528
Lectures
1/2
Functional Specificity among Ribosomal Proteins
Regulates Gene Expression; Komili et al. (2007), Cell
131; 557-571
Lectures
1/2
Comment in:
Yeast Ribosomes: Variety is the Spice of Life; McIntosh
and Warner; same issue
RNA helicase A is necessary for translation of selected
mRNAs; Hartman et al. (2006) Nature struct & mol biol
13, 509-516
Lectures
1/2
Comment in:
A new model for translational regulation of specific
mRNAs; Tettwiler & Lasko (2006) TIBS 31, 607-610
Immature small ribosomal subunits can engage in
translation initiation in Saccharomyces cerevisiae;
Soudet et al. (2009) EMBO J., 1-13
Lectures
1/2
Structures of the Ribosome in Intermediate States of
Ratcheting; Zhang et al. (2009) Science 325, 1014-1017
Lectures
1/2
Impaired Control of IHRES-Mediated Translation in Xlinked Dyskeratosis Congenita; Yoon et al. (2006)
Science, 902-906
Lectures
3/4
4E-BP Extends Lifespan upon Dietary Restriction by
Enhancing Mitochondrial Activity in Drosophila: Zid et al
(2009) Cell 139, 149-160.
Lectures
3/4
4E-BP functions as a metabolic brake used under stress
conditions but not during normal growth; Teleman et al.
(2005) Genes & Development 19, 1844-1848
mTORC1-Mediated Cell Proliferation, But Not Cell
Growth, Controlled by the 4E-BPs; Dowling et al. (2010)
Science 328, 1172-1176
Lectures
3/4
Cap-Independent Translation Is Required for StarvationInduced Differentiation in Yeast; Gilbert et al (2007)
Science 317, 1224-1227.
Lectures
3/4
The pathway of hepatitis C virus mRNA recruitment to
the human ribosome; Fraser et al (2009) Nature Struct.
& Molec. Biol. 16, 397-404
Lectures
3/4
The 5’-7-Methylguanosine Cap on Eukaryotic mRNAS
Serves Both to Stimulate Canonical Translation
Lectures
3/4
Initiation and to Block an Alternative Pathway; Mitchell
et al. (2010) Molecular Cell 39, 950-962
The molecular basis for the regulation of the capbinding complex by the importins: Dias et al. (2009)
Nature 16, 930-937
Lectures
3/4
eIF5 has GDI activity necessary for translational control
by eIF2 phosphorylation; Jennings & Pavitt (2010)
Nature 465, 378-381
Lectures
3/4
L13a Blocks 48S Assembly: Role of a general Initiation
Factor in mRNA-Specific Translational Control; Kapasi
et al. (2007) Molecular Cell 25, 113-126
Lectures
3/4
Translation elongation factor 1A is essential for
regulation of the actin cytoskeleton and cell morphology;
Gross & Kinzy (2005) Nature structural & molecular
biology 12, 772-778
Lectures
5/6
Hypusine-containing protein eIF5A promotes translation
elongation; Saini et al. (2009) Nature 459, 118-121
Lectures
5/6
eIF5A Promotes Translation Elongation, Polysome
Disaasembly and Stress Granule Assembly; Li et al.
(2010) PloS One 5, e9942
The Crystal Structure of the Ribosome Bound to EF-Tu
and Aminoacyl-tRNA; Schmeing et al (2009) Science
326, 688-694
Lectures
5/6
The Structure of the Ribosome with Elongation Factor G
Trapped in the Posttranslocational State; Gao et al
(2009) Science 326, 694-699
Formation of the First Peptide Bond: The Structure of
EF-P Bound to the 70S ribosome; Blaha et el. (2009)
Science 325, 966-970
Lectures
5/6
Comment in:
Leaps in Translational Elongation; Liljas (2009) Science
326, 677-618
Exotoxin A-eEF2 complex structure indicates ADP
ribosylation by ribosome mimicry; Jorgensen et al.
(2005) Nature 436, 979-984
Lectures
5/6
Structural basis for translation termination on the 70S
ribosome: Laurberg et al. (2008) Nature 454, 852-857
Lectures
7/8
Yeast Uri1p promotes translation initiation and may
provide a link to cotranslational quality control: Deplazes
et al. (2009) EMBO J. 28, 1429-1441
Lectures
7/8
Mature ribosomes are selectively degraded upon
starvation by an autophagy pathway requiring the
Ubp3p/Bre5p ubiquitin protease; Kraft et al. (2008)
Lectures
7/8
Nature Cell Biology 10, 602-610
Comment in:
Starved cells eat ribosomes; Nakatogawa & Ohsumi
(2008) Nature Cell Biology 10, 505-507
Quality control by the ribosome following peptide bond
formation; Zaher & Green (2009) Nature 457, 161-166
Lectures
7/8
Co-translational mRNA decay in Saccharomyces
cerevisiae: Hu et al (2009) Nature 461, 225-229
Lectures
7/8
PTC124 targets genetic disorders caused by nonsense
mutations; Welch et al. (2007) nature 447, 87-93
Lectures
7/8
Transient ribosomal attenuation coordinates protein
synthesis and co-translational folding: Zhang et al
(2009) Nature Struct. & Molec. Biol. 16, 274-280
Lectures
7/8