Biographical Sktch - UT Southwestern Medical Center at Dallas

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CURRICULUM VITAE
PERSONAL BACKGROUND:
Name:
Charles R. Rosenfeld, MD
Birth date and place of birth:
August 25, 1941
Atlanta, GA
Present address and telephone number:
4123 Shady Hill
Dallas, Texas 75229
(214) 357-5801
Marital Status:
Married - Ann Marie
3 sons (Evan, Scott, Jason)
EDUCATION BACKGROUND:
Emory University, Atlanta, Georgia - No degree
1959-1962
Emory University School of Medicine
Atlanta, GA - M.D.
1962-1966
POSTGRADUATE TRAINING:
Intern, Pediatrics
Yale-New Haven Medical Center
New Haven, CT
1966-1967
Resident, Pediatrics
Bronx Municipal Hospital Center and Albert Einstein
College of Medicine
Bronx, NY
1967-1969
Chief Resident, Pediatrics
Bronx Municipal Hospital & Albert Einstein College
of Medicine
Bronx, NY
1969-1970
Postdoctoral Fellow - Pediatric Pulmonary
Albert Einstein College of Medicine
Bronx, NY
1970-1971
Postdoctoral Fellow - Perinatal Medicine
University of Colorado Medical Center
Denver, CO
1971-1973
UNIVERSITY APPOINTMENTS:
Assistant Clinical Instructor in Pediatrics
Albert Einstein College of Medicine
Bronx, NY
2/17/2016
1969-1970
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Clinical Instructor in Pediatrics
Director of Pediatric Extended Home Care Unit
Albert Einstein College of Medicine
Bronx, NY
1970-1971
Assistant Professor of Pediatrics and OB/GYN
UT Southwestern Medical School
Dallas, Texas
1973-1977
Associate Professor of Pediatrics and OB/GYN
UT Southwestern Medical School
Dallas, Texas
1977-1981
Director, Training Program, Neonatal-Perinatal Medicine
Department of Pediatrics
UT Southwestern Medical Center
Dallas, Texas
1978-2007
Director, Division of Neonatal-Perinatal Medicine
Department of Pediatrics
UT Southwestern Medical Center
Dallas, Texas
1980-2008
Professor of Pediatrics and OB/GYN
UT Southwestern Medical Center
Dallas, Texas
1981-present
Assistant Professor of Anesthesiology
and Pain Management
1995-present
Faculty, Graduate Program in Integrative Biology
1996-present
Coordinator for Subspecialty Training
Department of Pediatrics
2007-present
HOSPITAL APPOINTMENTS:
Medical Director of Nurseries
Parkland Memorial Hospital, Dallas, Texas
1973-2006
Active Attending
Parkland Memorial Hospital, Dallas, Texas
1973-present
Active Attending
Children's Medical Center, Dallas, Texas
1973-present
Director of Neonatology
Children’s Medical Center, Dallas, Texas
1990-2006
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Consulting Staff – Pediatrics
St. Paul Hospital, Dallas, Texas
1973-present
Interim Medical Director, NNICU
Parkland Memorial Hospital, Dallas, TX
2000-2009
HONORS
Stipes Scholar, Emory University
1961
Alpha Kappa Alpha National Honorary in Sociology
Emory University
1962
Human Embryology and Development Study Section
of the National Institutes of Health
1978-1982
Perinatal Research Society
1981-present
Sigma Xi
1983-present
Ad Hoc Member, Various Study Sections of the NIH
1984-present
Ad Hoc Reviewer - Pediatric Research, Am J Physiol.,
Neuroendocrinology, Endocrinology, J Clin Endocrinol
Metab., Am J Obstet Gynecol, J Clin Invest, Science, Circ. Res.,
Cardiovas. Res., Biol Neonate, Arch Dis Childhood, Pediatrics,
J. Perinatology, J. Pediatrics, J. Appl. Physiol, Pediat Nephrology.
1984-present
Associate Editor Early Human Development
1986-present
Magness R.R., Brown C.E.L., Gant N.F., and Rosenfeld C.R. (Mentor). In vitro prostacyclin (PGI2) production by
uterine arteries from normotensive (NORM) and hypertensive pregnant women: Effects of angiotensin II (AII) and
saralasin (SAR). Society for Gynecologic Investigation, March 16-19, 1988 (Presented). President's Poster Award.
International Scientific and Program Committee, 8th & 9th
World Congress on Hypertension in Pregnancy,
Buenos Aires, Argentina and Sydney, Australia
November 8-12, 1992
March 13-15, 1994
Program Committee, Annual Meeting of the Society
for Gynecologic Investigation
1990-1992
NIH Reviewers Reserve
1992-present
Cox B.E., Ipson M.A., Kamm K.E., Shaul P.W., Horning K.M., and Rosenfeld CR (Mentor): Angiotensin II (AII)
myometrial smooth muscle receptors (MSMR) change subtype during ovine pregnancy. FASEB, Anaheim, CA,
April 1992. Dupont Merck Pharmaceutical Research Travel Award.
Ad Hoc Reviewer - Medical Research Council of Canada, CIHR
1992-2006
George L. MacGregor Professorship of Pediatrics
1993-present
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Associate Editor, (Journal of the Society for
Gynecologic Investigation) J Reproductive
Sciences
1993-2005
2005- present
Chern J, Rosenfeld C.R. (Mentor), and Kamm K.E. Smooth muscle (SM) myosin heavy chain isoforms (MHCI)
and protein in male fetal-neonatal sheep are developmentally regulated. The Southern Society for Pediatric
Research, New Orleans, LA, February 3-5, 1994. (Presented) Finalist for Young Investigator Award.
Sixteenth Edition of Men of Achievement
1994
Ad Hoc Reviewer - March of Dimes Birth Defects Foundation
1995
Cox B.E., Word R.A., Williams C.E., and Rosenfeld C.R. (Mentor). Alterations of myometrial and uterine artery
angiotensin II receptor subtype expression and function during human pregnancy. Southern Society for Pediatric
Research, New Orleans, LA, February 2-4, 1995. (Presented) Basic Scientist Young Investigator Award.
Editorial Board, American Journal of Physiology:
Regulatory, Integrative and Comparative Physiology
1996-1999
Texas Hall of Fame
1996
The Best Doctors in America: Central Region
1996-1997, 2001-2004, 2007-2008
Who's Who in Medicine and Health Care (1st Edition)
1996-present (reselected 2006 – 2007)
Kaiser JR, Cox B.E., and Rosenfeld C.R. (Mentor). In fetal sheep angiotensin II (ANG II)-induced increases in
mean arterial pressure (MAP) are mediated through umbilical artery (UA) AT1 receptors. Southern Society for
Pediatric Research, New Orleans, LA, January 31 - February 2, 1996. (Presented) Finalist Basic Scientist Young
Investigator Award.
Arens YHJM, Rosenfeld C.R. (Mentor), Jabbar W, and Kamm K.E. Comparison of expression of contractile
proteins and myosin heavy chain isoforms (MHCI) in ovine aorta (Ao) and bladder from early fetal through late
neonatal periods. Southern Society for Pediatric Research, New Orleans, LA, January 31 - February 2, 1997.
(Presented) Basic Scientist Young Investigator Award.
Salhab W, Shaul P.W., Cox B.E., and Rosenfeld C.R. (Mentor). Nitric oxide synthase activity in ovine uterine
arteries is increased following acute estradiol-17 exposure. The Society for Gynecologic Investigation, San Diego,
CA, March 19-22, 1997 (Presented). Recipient of the President’s Presenter’s Award.
Ad Hoc Reviewer for The Wellcome Trust
1997-present
Higher Manpower Development Program Consultant, Ministry of Health, Singapore, October 20-November 1,
1998. Visited and lectured at all major government supported hospitals, and consulted on program development.
Best Doctors in Dallas, Dallas Magazine
1998, 2002 - 2005
Salhab WA, Shaul P.W., Cox B.E., Rosenfeld C.R. (Mentor). Acute and chronic estrogen treatment modulate
uterine artery type I and III nitric oxide synthases. Section on Perinatal Pediatrics, Annual Meeting of the
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Academy of Pediatrics, October 8-13, 1999. (Presented) Mead Johnson Young Investigator Award for Basic
Science.
Reviewer for Medical Research Council of Canada, “Initial Interdisciplinary Health Research Teams” Grants
Committee. January 1, 2000-December 31, 2000.
Nagar D, Rosenfeld C.R. (Mentor). Estrogen increases expression of the β1-subunits of the large conductance
calcium activated potassium channel in ovine uterine vascular and visceral smooth muscle. Southern Society for
Pediatric Research, February 13-15, 2004, New Orleans, LA. (Young Investigator Award for Basic Research)
Koch J., Hensley G., Ramaciotti C., and Rosenfeld C.R. (Mentor). A Prospective study characterizing ductus
arteriosus closure in inborn neonates <1000 G birth weight. Southern Society for Pediatric Research, February 25,
2005, New Orleans, LA. (Young Investigator Award for Clinical Research)
Founder’s Award for Research Improving the Health of Children, Southern Society for Pediatric Research,
February 25, 2005, New Orleans, LA.
Who’s Who in America
2005-present
Who’s Who in the World
2005-present
Fellow, Cardiovascular Section of American Physiological Society
March 2005
Best Doctors in America
2005-present
Canadian Institute of Health Research,
Clinical Investigation A Committee
December 12 – 13, 2005
Who’s Who in Science and Engineering
2006-present
Parkland Memorial Hospital, Legends Award for Outstanding Service
2007
Ennis BJ, Roy L, Rosenfeld CR (Mentor). Basal total and free cortisol measurements are unrelated to blood
pressure in the first postnatal week in neonates 28-32 weeks gestation. American Academy of Pediatrics 2007
National Conference and Exhibition, October, 2007. (Klaus Award presentation)
Who’s Who Among Executives and Professionals
2008-
Guide to America’s Top Pediatricians
2008-
Who's Who Among Executives and Professionals, "Honors Edition"
2008-2009
Student Teaching Award, Senior Acute Care Medicine, Class of 2008
2008
Duncan AF, Heyne RJ, Morgan JS, Ahmad N, Rosenfeld CR (Mentor). Systolic Blood Pressure (SBP) in Very-Low-BirthWeight Infants (VLBW) Exceeds A Reference Population in the First 3 Yr of Life. American Academy of Pediatrics
2009 National Conference and Exhibition, October 17, 2009. Klaus Award presentation
Referee for abstracts, Southern Society for Pediatric Research
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2009
NIH Special Emphasis Panel, Pregnancy, Reproductive Biology and
Development SRG 2010/01 ZRG1 EMNR-B
2009
Punjwani P, Rosenfeld CR, Ramaciotti C. Echocardiographic Prediction of Spontaneous Closure of the Ductus
Arteriosus in Neonates Less Than 30 Weeks of Gestation. Outstanding Poster Award, 1st Annual Senior Fellows’
Research Day, May 25, 2010, UT Southwestern Medical School, Dept. of Pediatrics and AAP Travel Award,
Section on Perinatal Pediatrics, October 1, 2010.
Canadian Institute of Health Research, Review Committee
Clinical Investigation A Committee
December 7 – 9, 2010
Co-moderator, Session on Maternal Physiology and Biology
March 18, 2011
Abstract Review Committee
Judge, New Investigator Poster Presentations
Annual Meeting, Society for Gynecologic Investigation, Miami Beach, FL
Judge, New Investigator Poster Presentations
Abstract Review Committee
Annual Meeting, Society for Gynecologic Investigation, San Diego, CA
March 22, 2012
Symposium Review Committee, Pediatric Academic Societies
Annual Meeting
April 28, 2012
Frankfurt J, Duncan A, Heyne R, Rosenfeld CR. Growth Patterns in Preterm Very-Low-Birth-Weight (PTVLBW) Infants at 1-3yrs Correlate with Elevated Serum Leptin. Pediatric Academic Societies’ 2012 Annual
Meeting, Boston, MA. April 27-May 1, 2012. (Oral presentation, chosen CTSA Child Health Research Fellow,
Travel Award)
“Top Doctors", as recognized by US News & World Report
May 2012
PROFESSIONAL ORGANIZATIONS:
Southwestern Gynecologic Assembly
1974-1980
American Academy of Pediatrics
Section on Perinatal Pediatrics
1976-present
Texas Perinatal Association (Founding member)
1976-2008
Society for Pediatric Research
1977-present
Society for Gynecologic Investigation
1978-present
The Endocrine Society
1979-present
American Thoracic Society
1980-1988
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Perinatal Research Society
1981-present
The American Pediatric Society
1983-present
American Association for the Advancement of Science
1983-present
American Physiological Society
1985-present
International Society for the Study
of Hypertension in Pregnancy
1985-2004
American Pediatric Program Directors
2008-present
American Heart Association
1999-present
LICENSURE:
Georgia 1966, New York 1970, California 1970, Texas 1973
CERTIFICATION:
Diplomate, American Board of Pediatrics
Diplomate, Sub-Board of Neonatal-Perinatal Medicine
July 1, 1971
November 15, 1975
MILITARY:
Lt. Commander, U.S. Navy, Discharged,
February, 1974
COMMITTEES:
Regional Medical Program of Texas, Inc.
Ad Hoc Advisory Committee for Perinatal Medicine
1974-1976
Task Force on Perinatal Health Care
Regional Health Planning Council of the North
Central Texas Council of Government
1974-1975
Board of Directors, Dallas Chapter of the American
Lung Association
1975-1982
Infection Control Committee
Parkland Memorial Hospital
1975-1983
Texas Perinatal Association, Steering Committee
1976-1978
State Advisory Board and Regional Representative
1976-1977
Texas Perinatal Association (Regional V)
1981-1983
Nutrition Advisory Committee
Dallas Public Health Department
1976-1982
Texas Area 5 Health Systems Agency, Inc.
1979-1980
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Study Committee for the Perinatal Health
and Facilities Report of 1979
Committee of Delegates
University of Texas Health Science Center at Dallas
1979-1980
Chairman, Committee on Pediatric Lung Diseases
Dallas Chapter of the American Lung Association
1979-1982
Space Allocation Committee - Medical Services
Parkland Memorial Hospital
1979-1986
Grants Management Advisory Committee
UT Southwestern Medical School
1980-1981
Continuing Education Committee
UT Southwestern Medical School
1980-1984
Capital Budget Committee - Parkland Memorial Hospital
1980-1991
Upper Trinity Perinatal Association - Regional V
Vice President
1981-1982
Chairman, Health Professional Advisory Committee
National Foundation - March of Dimes, North Texas Chapter
1981-1984
Animal Resources Center Advisory Committee
UT Southwestern Medical School, Chairman (1987-1991)
Ad hoc member
1981-1991
Standardization Subcommittee
Medical Advisory Council, Parkland Memorial Hospital
1982-1983
Risk Management Committee
University of Texas Health Science Center at Dallas
1982-1983
Long Range Planning Committee
National Foundation - March of Dimes, North Texas Chapter
1982-1984
Treasurer, Board of Directors
A.W. Harris Faculty-Alumni Center
1982-1985
Promotions and Tenure Committee
UT Southwestern Medical School
1983-2004
Chairman, Institutional Review Board
for Animal Research
1985-1987
Academic Support Services Committee
1988-1991
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1991-2004
UT Southwestern Medical Center
Board of Directors, Dallas Aquatic Club
Secretary (1988-1991), Vice President (1991-1996)
1988-1996
Institutional Six Year Plan-Academic Support
Services and Administration & Business Affairs Committee
1991-present
Program Committee, Annual Meeting,
the Society for Gynecologic Investigation
1989-2008
Search Committee, Director of Animal Resources,
UT Southwestern Medical School
1995-1996
Performance Improvement Committee, Dallas County
Hospital District, Parkland Memorial Hospital
1995-2000
Chairman, Performance Improvement Committee
Nursery Services, Parkland Memorial Hospital
1998-present
Executive Committee, Section of Perinatal Pediatrics
American Academy of Pediatrics, District VII
2002-2008
Medical Advisory Council, Pediatric Representative
Parkland Memorial Hospital
2002-2009
Promotions Committee, Department of Pediatrics
2005-present
Imaging Strategy Committee
Parkland Memorial Hospital
2008-2009
Critical Care Committee
Parkland Memorial Hospital
2009-2010
Leadership Committee, WISH, Nursery Services
Parkland Memorial Hospital
2007- present
Training Program Directors’ Committee
Children’s Medical Center
2010- present
CONTRACTS AND GRANTS:
Principal Investigator, National Institutes of Health Grant No. HD08783 "Studies of Uteroplacental Circulation",
$158,708, 1974-1977.
Principal Investigator, National Institutes of Health Grant No. HD08783 "Studies of Uteroplacental Circulation",
$329,480, 1977-1981
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Co-investigator, National Institutes of Health Grant No. NIH-1-PO1-HD13912, "Fetal Lung Maturation:
Prevention of RDS", J.M. Johnston, P.I., $225,000, 1980-1985 (5% effort).
Principal Investigator, National Institutes of Health Grant No. HD08783 "Studies of Uteroplacental Circulation",
$613,567, 1981-1986.
Co-Investigator, "In Vitro Vascular Reactivity During Pregnancy and Preeclampsia". American Heart Association Texas Affiliate. $25,000/year, 1985-1986.
Co-Investigator, "In Vitro Vascular Reactivity During Pregnancy and Preeclampsia." American Heart Association Texas Affiliate. Competitive Renewal $27,500/year, 1986-1987.
Associate Director, Co-Principal Investigator (with Joseph B. Warshaw), NIH Training Grant No. 1-T32
HD07308-01, "Research in Developmental Medicine" $84,901, 1986-1991.
Principal Investigator, National Institutes of Health Grant No. HD20720-01, "Fetal Hormonal Adaptation to
Intrauterine Stress", $383,096, 1986-1989.
Co-Investigator, "In Vitro Vascular Reactivity During Pregnancy and Preeclampsia." American Heart Association
- Texas Affiliate. Competitive Renewal. $55,000 total award, 1987-1989.
Principal Investigator, Director, NIH Training Grant No. 1-T32-HD07308-02, "Research in Developmental
Medicine", 1987-1991.
Principal Investigator, National Institutes of Health Grant No. HD08783, "Studies of Uteroplacental Circulation",
$952,982, 1986-1992, $52,800, 12/91-11/92.
Principal Invest, Project 5, "Lung Development in Stressed Fetuses"; Project Director, Jack Johnston, PhD., NIH
Grant No. PO1-HD13912-09, "Fetal Lung Maturation: Prevention of RDS", $905,116, 1987-1993.
Co-investigator, National Institutes of Health Grant No. NIH-5-P50-HD11149, "Initiation of Human Labor:
Prevention of Prematurity", P.C. MacDonald, P.I.; Project VI "Regulation of Steroidogenesis and fetal adrenals
placenta during pregnancy and parturition, J.I. Mason, P.I., $ 816,907, 1988-1993.
Principal Investigator, National Institutes of Health Grant No. 5 RO1 HD08783-19, "Studies of Uteroplacental
Circulation", $1,050,215, 1992-1997.
Co-investigator, National Institutes of Health Grant No. NIH-5-P50-HD11149, "Initiation of Human Labor:
Prevention of Prematurity", P.C. MacDonald, P.I.; Project V "Regulation of Steroidogenesis and fetal adrenals
placenta during pregnancy and parturition, J.I. Mason, P.I., $ 634,096, 1993-1998.
Co-Investigator, NIH-R01-HL-49210-01, "Endothelium-Derived Vasodilators During Pregnancy", R.R.
Magness, PI; Total Annual Direct Costs $109,185; 1993-1997.
Principal Investigator, Neurex Pharmaceutical, “Studies of Fenoldopam, a DA2 Agonist, in Pregnancy; Total
award $69,379; 1998-2000.
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Principal Investigator, National Institutes of Health Grant No. 5 RO1 HD08783-24, "Studies of Uteroplacental
Circulation", $1,143,483, 1998-2004
Principal Investigator, Forest Pharmaceuticals, “Characterization of Ductus Arteriosus in Neonates <1000grams”,
Fellows Award Program to Shannon Brown, MD, $7,000, 2000-2002.
Principal Investigator, National Institutes of Health Grant No. 5 RO1 HD08783-28A1, "Studies of Uteroplacental
Circulation", $1,405,108, 2004-2009.
*Co-Investigator, Farmacon-IL, LLC - FCR-00-01/Ross CB88, AA Randomized, Double-Blind Study of Ibuprofen
L-Lysine Intravenous Solution in Premature Infants for the Early Treatment of PDA@, 2003-2004.
Principal Investigator, National Institutes of Health Grant No. 5 U10 HD040689-04, “Cooperative Multicenter
Neonatal Research Network”, $341,786; 2004-2006.
External Advisor. National Institutes of Health Grant No. 1 T32 HD046420-01, "Training in Developmental
Biology", Principal Investigator De-Ann M. Pillers, M.D., Ph.D., Department of Pediatrics, Oregon Health and
Science University, 2005 – 2009.
Mentor for Becky Ennis, M.D. (Postdoctoral Trainee). M. Klaus Award, Section on Perinatal Pediatrics,
American Academy of Pediatrics, Hormonal Regulation of Blood Pressure in Neonates <32 Weeks Gestational
Age. $5,000, 2004-2005.
Mentor for Andi Duncan, M.D. (Postdoctoral Trainee). M. Klaus Award, Section on Perinatal Pediatrics,
American Academy of Pediatrics, Effects of Very Low Birth Weight, Prematurity and Postnatal Growth on Blood
Pressure During the First 3 Years of Life. $5,000, 2007-2008.
Principal Investigator, National Institutes of Health Grant No. 5 RO1 HD008783-33A1, "Studies of
Uteroplacental Circulation", $1,962,500, 2009-2014.
Co-investigator, Mentor for Lena Chalak, MD and Debra Weinberger, MD, National Institutes of Health Grant 1KL2-RR024983, Clinical and Translational Science Award, 2007-2012
Mentor for Michel Mikhael, MD (Postdoctoral Trainee). Children’s Medical Center Foundation Award for “Perioperative assessment of the hypothalamic-pituitary-adrenal axis predicts postoperative morbidity in neonates
undergoing cardiac surgery,” $30,000, 2011-2012.
POSTGRADUATE EDUCATION
Director, "Postgraduate Course in High-Risk Pregnancy and Perinatal Medicine," Texas Medical Association, May
7, 1976.
Co-Director, "Southwestern Perinatal Nursing Seminar," The University of Texas Health Science Center at Dallas,
June 1-5, 1976.
Director, "Annual Southwestern Nursing Seminar," The University of Texas Health Science Center at Dallas,
1977-present.
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Director, "Seminar on Critical Evaluation of Fetal-Neonatal Care," Symposia Medicus, Park City, Utah, February
13-20, 1982.
Co-Director, "Clinical Issues in Perinatal Care," Contemporary Forums, Park City, Utah, February 5-12, 1983.
Co-Director, "Perinatal Dilemmas," Contemporary Forums, Park City, Utah, February 25 - March 3, 1984.
Co-Director, "Clinical Dilemmas in Perinatal Medicine," Contemporary Forums, New York City, New York,
October 11 - October 14, 1984.
Co-Director, "Perinatal Dilemmas," Contemporary Forums, Park City, Utah, February 9-16, 1985.
Co-Director, South Central Conference for Perinatal Research, Austin, TX. Mead Johnson Nutritionals, Oct 19952007.
Co-Chairman, Symposium on “The Renin-Angiotensin System and Development”, Experimental Biology 2003,
The American Physiological Society: Endocrinology and Metabolism Section, San Diego, CA, April 13, 2003.
Co-Director, AAP District VII Leadership Development Seminar, Dallas TX, October 19-20, 2007
Coordinator for Subspecialty Training, Department of Pediatrics, 2007-present
CONSULTATIONS:
Review of Neonatal Facilities, Department of Health, Singapore, October 30-November 1, 1998.
Review, Division of Neonatal Medicine, Department of Pediatrics, University of Oklahoma School of Medicine;
September, 2000.
5 year review, CMRI Reba McIntire Chair in Neonatal Medicine. University of Oklahoma School of Medicine,
Department of Pediatrics, December 14-16, 2006.
Review, Division of Neonatal Medicine, Department of Pediatrics, University of Arkansas School of Medicine;
April, 2006.
INVITED TALKS:
"Renin Angiotensin System," International Symposium on Uterine and Placental Blood Flow, Chicago, IL, March
24, 1980.
"Uterine Blood Flow and Placental Transport," Clinical Nutrition and Early Development branch of the Center for
Research for Mothers and Children, National Institute of Child Health and Human Development, "Workshop on
Intrauterine Growth Retardation," Bethesda, MD, July 17-20, 1983.
"The Ewe: A model for cardiovascular changes in pregnancy," American Association for Laboratory Animal
Science, San Antonio, TX, November 10, 1983.
"Arginine Vasopressin in Fetal Adaptation," Symposium on Perinatal Endocrinology, University of Maryland
Medical School, Baltimore, MD, June 17, 1985.
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"Development of Vascular Refractoriness in Pregnancy," Visiting Professor, Department of Reproductive
Medicine, University of California at San Diego, February 20, 1986.
"Alterations in the Uterine Vascular Bed During Ovine Pregnancy," 17th Annual Meeting of the Perinatal
Research Society, Carefree, AZ, September 29, 1986.
Visiting Professor, Department of Obstetrics/Gynecology and Pediatrics, Southern Illinois University School of
Medicine, November 5-6, 1986.
"Maternal Cardiovascular Adaptation to Pregnancy," Division of Vascular Medicine and Atherosclerosis, Dept. of
Medicine, Brigham and Women's Hospital, Harvard Medical School, December 11-12, 1986.
Visiting Professor, Department of Pediatrics, Washington University School of Medicine, January 22-23, 1987.
Gordon Conference on Angiotensin II, "Developmental Aspects of the Renin-Angiotensin System"
Santa Barbara, CA, February, 1987.
Visiting Professor, Department of Pediatrics, Loyola University Stritch School of Medicine, November 3-4, 1987.
"Arginine Vasopressin in Various Aspects of Fetal Adaptation," 11th Japanese Perinatal ME Conference,
Matsuyama, Japan, July 23, 1988.
Rosenfeld, CR: "Fetal Lung Development." Videotape for American Association for Respiratory Care, 1988.
Visiting Professor, Department of Physiology, Dartmouth School of Medicine, Hanover, VT, October 4-5, 1988.
"Amniotic Fluid and the Fetus," Symposium on the Newborn Kidney, Royal Postgraduate Medical School,
Institute of Obstetrics and Gynecology, London, England, December 9, 1988.
Visiting Professor, Departments of Pediatrics and Physiology, "Neuroendocrine Aspects of Fetal Adaptation" and
"AVP and CRF, Which is the CRF?" Bowman Gray School of Medicine, Wake Forest University, Winston Salem,
NC, January 24-26, 1989.
Visiting Professor, South Australian and Australian Perinatal Society, Adelaide, Australia, September 22-October
9, 1989.
Guest Lecturer, New Zealand and Perinatal Society, Auckland, Australia, October 11-12, 1989.
"Vasopressin in the fetus and neonate," Symposium on Neonatal Hypertension, American Heart Association and
National Institutes of Health, Bethesda, MD, October 17-18, 1989.
Visiting Professor, McGill University, Departments of Pediatrics and Obstetrics/Gynecology; "Endocrine Control
of Uteroplacental Blood Flow." September 26-27, 1991. Montreal, Quebec.
Visiting Professor, University of Montreal, Department of Pediatrics and Obstetrics/ Gynecology; "The Role of
Angiotensin II in Fetoplacental and Uteroplacental Blood Flow." October 2, 1991, Montreal, Quebec.
Chairman, Postgraduate Seminar on Cardiovascular Changes in Pregnancy, 64th Scientific Sessions, American
Heart Association, November 11-14, 1991, Anaheim, California
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Nelson Foundation Professorship, Departments of Physiology and Reproductive Animal Sciences, University of
Missouri School of Medicine, "Mechanisms for refractoriness to ANG II during ovine pregnancy. April 20-21,
1992, Columbia, Missouri.
Visiting Professor, Department of Pediatrics, University of Missouri School of Medicine, "The use of the white
blood cell count in the diagnosis of neonatal infection and alterations associated with maternal hypertension",
April 21, 1992, Columbia, MO.
Serono Foundation Symposia, "Vascular aspects of the renin-angiotensin system in the fetus", July 6-7, 1992,
Paris, France.
Parke-Davis Symposium, Biochemical properties and physiological roles of the AT2 receptor, "Modification of
angiotensin II receptor subtypes during ovine pregnancy and the puerperium." July 10-11, 1992, Ypsilanti, MI.
Gordon Research Conference on Angiotensin II, "Vascular and uterine angiotensin II receptor subtypes in
pregnancy" February 8-12, 1993, Oxnard, CA.
Special Lecturer, 14th Japan Society for the Study of Toxemia in Pregnancy, "Vascular angiotensin II receptors
during pregnancy and their role in cell function," September 3, 1993, Matsuyama, Japan.
Visiting Professor, Dept. of Obstetrics and Gynecology, School of Medicine, Ehime University, "The mechanisms
controlling uteroplacental blood flow in pregnancy," September 4, 1993, Kumamoto, Japan.
Chairman and Speaker, Symposium on Control of the Uteroplacental Circulation, Presentation: "Growth and
Development of the Uteroplacental Vascular Bed During Pregnancy," The 9th Congress of the International
Society for the Study of Hypertension in Pregnancy, March 16-19, 1994, Sydney, Australia.
Symposium on Angiotensin Receptor Subtypes and Their Pharmacology, "Developmental and Reproductive specs
of the Angiotensin II Receptor," The International Congress of Pharmacology, July 24-29, 1994, Montreal,
Canada.
Visiting Professor, Departments of Perinatal Biology and Pediatrics, Lomo Linda University School of Medicine,
Lomo Linda, CA "Neonatal neutrophil values: Developmental and perinatal regulation" and "Mechanisms
controlling uteroplacental blood flow during pregnancy," May 25-27, 1995.
Speaker, ASPET colloquium "Effects of Gonadal Steroids on Vascular Function" in Conjunction with
Experimental Biology '96, "Estradiol modulates ovine uterine blood flow and systemic vascular resistance," April
17-18, 1996, Washington, DC.
Speaker, International Perinatal Collegium, “Differential Maturation of Umbilical and Peripheral Artery Smooth
Muscle in Fetal Sheep,” July 18-22, 1997, Mont Tremblant Quebec, Canada.
Speaker, FASEB Summer Research Conference, “Perinatal Regulation of the Cardiovascular System,” August 1722, 1997, Copper Mountain, CO.
Visiting Professor, Department of Physiology, University of Florida, “Mechanisms responsible for systemic and
uterine responses to angiotensin II in pregnancy,” November 17, 1997, Gainesville, FL.
Speaker, Annual Symposium on Fetal Physiology “Mechanisms Regulating Angiotensin II Responsiveness by the
Uteroplacental and Systemic Circulations.” Annual Meeting of the Society for Gynecologic Investigation, March
10, 1998, Atlanta, GA.
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Visiting Professor, University of Utah School of Medicine, “Neutrophilic Parameters in the Diagnosis of Neonatal
Infection”, “Pulmonary Artery Smooth Muscle: Ontogenic Changes and the Effects of Pulmonary Hypertension,”
March 30-31, 1998, Salt Lake City, UT.
Speaker, Symposium in Honor of Giacomo Meschia, MD, Depts of Physiology and Pediatrics, University of
Colorado School of Medicine, “Mechanism of Estrogen-Induced Changes in Uterine Blood Flow,” June 11, 1998,
Denver, CO.
Invited Speaker, 2nd Annual Scientific Meeting of Obstetrics and Gynecology, “Mechanisms Modifying
Uteroplacental Blood Flow and Their Effects on the Fetus,” “Evidence-based Ethics and the Care of the Preterm
Infant,” “Attenuated Uteroplacental Responses to Angiotensin II and Pregnancy-Induced Hypertension.” KK
Women’s and Children’s Hospital, October 30-November 1, 1998, Singapore.
Speaker, Symposium on Nongenomic Effects of the Gonadal Steroids on Vascular Function: “Mechanisms
Mediating Estrogen-Induced Increases in Ovine Uterine and Uteroplacental Blood Flow.” Experimental Biology
99, April 17-21, 1999, Washington, DC.
Speaker, Respiratory Care Lecture Series 2000: “Meconium Aspiration Syndrome.” Parkland Health and Hospital
System, May 5, 2000, Dallas, TX.
Speaker, Neonatal Course for Senior Paediatricians, The Lesley Cooper Memorial Lecture: “Patent Ductus
Arteriosus: An Old Problem with New Delimmas.” Imperial College School of Medicine, November 27 December 1, 2000, London, England.
Speaker, “The development and maturation of pulmonary artery smooth muscle and its role in the development of
pulmonary hypertension.” GROW Research Institute for Growth & Development, Maastricht University, January
25, 2001, Maastricht.
Speaker, Annual Neonatal Education Program, “Diagnosis of Neonatal Infection: Use of the Peripheral blood
count.” University Hospital Maastricht, Division of Neonatology, January 26, 2001, Maastricht.
Speaker, “The Role of Animals in Biomedical Investigation: Understanding Pregnancy and Uteroplacental Blood
Flow.” Southern Methodist University, Department of Biological Sciences and Maguire Center for Ethics and
Public Responsibility, October 23, 2001, Dallas, TX.
Speaker, “Patent Ductus Arteriosus: Mechanisms of Closure and Non-closure in Term and Preterm Neonates.”
Grand Rounds, University of Texas Southwestern Medical Center at Dallas, February 13, 2002, Dallas TX.
Speaker, “Angiotensin II and Fetal Vascular Function.” 6th Symposium International de Néphrologie Périnatale,
June 21-22, 2002, Bandol, France.
Speaker, “Uterine Blood Flow Measurements and Control.” 9th Annual South Central Conference on Perinatal
Research, October 8-10, 2002, Austin, TX.
Speaker, “Ontogeny of Angiotensin Receptor Expression During Ovine Development,” Symposium on The ReninAngiotensin System and Development, Co-Chairman, Experimental Biology 2003, April 13, 2003, San Diego,
CA.
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Speaker, “The Renin-angiotensin System in The Newborn Sheep,” International Colloquium on Perinatal
Medicine, June 28-July 2, 2003, Tours, France.
Speaker, “Fetal Growth Restriction: Pathogenesis and Outcome,” The Fetus & Newborn: State-of-the-Art Care,
September 22-24, 2003, New Orleans, LA.
Speaker, “Mechanisms for Failure of Ductal Closure in Very Preterm Neonates,” The Fetus & Newborn: State-ofthe-Art Care, September 22-24, 2003, New Orleans, LA.
Speaker, “Ontogeny of Angiotensin II Receptors in Vascular Smooth muscle: Relationship to Pressure Regulation
in the Fetus and Neonate,” “Control of the Uteroplacental Circulation and Fetal Growth.” 63rd Perinatal &
Developmental Medicine Symposium, “Fetal Origins of Adult Disease,” November 20-23, 2003, Marco Island,
FL.
Visiting Professor, Department of Pediatrics, Division Neonatal Medicine, University of Illinois School of
Medicine at Chicago; “Pathogenesis of PDA in VLBW neonates” and “The Role of the Renin-Angiotensin System
in Vascular Smooth Muscle During Development”, September 9-10, 2004.
Founders Award, Southern Society for Pediatric Research. “Blood pressure regulation in the fetus and neonate:
Development of the renin-angiotensin system.” New Orleans, LA, February 25, 2005.
Visiting Professor, Oregon Neonatal Seminar Series, Oregon Health Science Center; "Vascular smooth muscle
development and the effects of fetal growth restriction;” Pediatric Grand Rounds, "Patent ductus arteriosus in
extremely-low-birth-weight neonates: Natural history and development," June 8 – 10, 2005.
UIC Specialty Review in Neonatology/Perinatology. “Physiology and Management of Blood Pressure in the
Newborn.” Chicago, IL August 22-26, 2005
Visiting Professor, Emory University School of Medicine; “Pediatric Grand Rounds: “Understanding Blood
Pressure Regulation and Management in the Neonate;” Perinatal Research Conference: “Fetal Growth and Wellbeing: Mechanisms Modulating Uteroplacental Blood Flow in Pregnancy.” February 15-16, 2006.
Invited Speaker, Network of GA Neonatologists: “Patent Ductus Arteriosus in Extremely-Low-Birth-Weight
Neonates: Physiology, Pathology and Treatment,” Atlanta, GA, February 15, 2006.
Billy F. Andrews Lectureship in Pediatrics: Department of Pediatrics, University of Louisville School of Medicine.
“Patent Ductus Arteriosus in Neonates <1000 gm: Physiology, Pathology and Treatment.” Louisville, KY,
October 20, 2006.
International Conference on Meconium Aspiration Syndrome and Meconium-induced Injury. “Molecular Basis of
Meconium-induced Lung Injury.” Chicago, IL, March 23-24, 2007.
UT Southwestern Obesity Alliance, Weekly Seminar Series on Nutrition, Metabolism and Obesity. "Insulin
Resistance in Hispanic Large For Gestational Age Neonates at Birth” Dallas, TX, December 13, 2007.
UT Southwestern, Department of Internal Medicine, Hypertension Grand Rounds. "Impact of fetal-neonatal
programming on adult diseases-Effects of fetal growth and preterm birth.” Dallas, TX, May 30, 2008.
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Visiting Professor, Departments of Obstetrics/Gynecology and Pediatrics, University of Western Ontario, London,
Ontario, Canada. OB/GYN Grand Rounds: “Abnormal Fetal Growth and Preterm Birth May Predict Future
Childhood and Adult Risk for Disease.” Canadian Health Research Institute Lecture: “Vascular Development in
the Fetus and Neonate and the Effects of Fetal Growth Restriction.” October 28-30, 2008.
Speaker, Clinical Advances in Pediatrics Symposium, Children’s Mercy Hospital in Kansas City, MO. “Diagnosis
of Infection in the Newborn: Use of the Lab and Cultures,” “Implications of Fetal Growth and Preterm Delivery on
Childhood and Adult Diseases,” and “Triage and Care of the Late-Preterm Neonate: Experience in a Large
Hospital.” Nov 21, 2008.
Visiting Professor, Division of Neonatal Medicine, University of Missouri at Kansas City Medical School and
Children’s Mercy Hospital. Division Conference: Understanding Mechanisms Regulating Uteroplacental Blood
Flow in Pregnancy: How did I get here?” November 20, 2008.
Visiting Professor, Departments of Obstetrics/Gynecology and Neonatal Medicine, University of Tennessee
School of Medicine. OB/GYN Grand Rounds: “Mechanisms Modulating Uterine Vascular Sensitivity to
Norepinephrine and Angiotensin II in Human Uterine Arteries”; Neonatal Grand Rounds: “Diagnosis of Neonatal
Infection: Revisiting the Manroe et al Neutrophil Values. November 8, 2011.
TRAINEES:
Medical Students:
Richard Rivera
UT Southwestern Medical School
Summer, 1977
G. Marc Jackson
UT Southwestern Medical School
Summer, 1983
Charles A. Iliya
UT Southwestern Medical School
Studies of uteroplacental blood flow.
Summer, 1984
Starling Corbett
UT Southwestern Medical School
Summer, 1990
Studies of neonatal intracranial hemorrhage.
Yvonne Arens
Rijksuniversiteit Limburg,
Maastricht, The Netherlands
Studies of smooth muscle development.
Jennifer Chern
UT Southwestern Medical School
Summer, 1993
Studies of vascular smooth muscle maturation.
René Chapados
Sarnoff Fellow, Univ. of Chicago
1993 - 1994
School of Medicine
Pulmonary vascular smooth muscle development.
Desiree van den Bongard
Rijksuniversiteit Limburg,
Fall, 1995
Maastricht, The Netherlands
Studies of vascular smooth muscle maturation.
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Fall, 1992
Liedeke van der Steeg
Rijksuniversiteit Limburg,
Fall, 1995
Maastricht, The Netherlands
Studies of vascular smooth muscle maturation.
Senthil Sankaralingam
University of Hawaii School of Medicine
Summer, 1999
Society of Pediatric Res Summer Fellow
Effects of estrogen on smooth muscle proteins.
Shilpa Miniyar
UT Southwestern Medical School
Folashade Afolabi
UT Southwestern Medical School
2003-2007
Neutrophilic values in the diagnosis of nosocomial infection.
Renaud Viellevoye
University of Liege
Belgium
May – June 2004
Laura R. Ley
UT Southwestern Medical School
Summer, 2005
Jules Bergmann
UT Southwestern Medical School
Summer, 2010
Maternal weight gain, LGA and childhood obesity.
Summer, 2002
49th Annual Medical Student Research Forum Poster Award
Helena Wojciechowski
UT Southwestern Medical School
Summer, 2011
Early pregnancy nutrient restriction and uteroplacental
Expression of BKCa
Neonatal-Perinatal Fellows:
Barbara L. Manroe, MD
UT Southwestern Medical School
Assistant Professor, UT Southwestern
Private practice
1975 – 1978
1978 - 1981
1981
Jaime A. Furzan, MD
Univ. of Carabobo, Venezuela
Univ. of Carabobo, Venezuela
1978 - 1980
1980
S. Wiriyathian, MD
Maimonides Medical Center
Private Practice, Lubbock, TX
1980 - 1983
(w/John Porter, PhD)
Daniel J. Faucher, MD
University of Montreal
1983 - 1985
(w/John Porter, PhD)
1985-1987
1987 - present
Assistant Professor, UT Southwestern
Associate Professor, McGill University
David J. Annibale, MD
University of North Carolina
Presently at Medical Univ. of S. Carolina
Director, Division Neonatal Medicine
1987 - 1990
(w/Kris Kamm, PhD)
Larry A. Wallin, MD
University of Utah
Private Practice
1987 - 1990
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Hasu R. Mackanjee, MD
Hospital for Sick Children
University of Toronto
St. Joseph's Health Center
London, Ontario, Canada
Private Practice, South Africa
1987 - 1989
(w/Phil Shaul, MD)
1989-1991
Blair E. Cox, MD
Creighton Univ. Medical Center
Associate Professor, UT Southwestern
Med School
1990 - 1993
(w/Phil Shaul, MD)
1994 - Died 2005
Merle A. Ipson, MD
UT Southwestern Medical School
1991-1994
(w/Kris Kamm, PhD)
1994-present
Professor, Texas Tech Medical School,
El Paso, TX
Jeffrey Kaiser, MD
Mt. Sinai Med Center, New York
1994 - 1997
Associate Professor, University of Arkansas
1997 - 2011
Medical Center, Little Rock, AR
Professor, Baylor College of Medicine
2012 –
Texas Children’s Hospital, Director Clinical Research
Walid Salhab, MD
Le Bonheur Children's Hospital
Assistant Professor, UT Southwestern
Medical School
Private Practice
1995 - 1998
(w/Phil Shaul, MD)
1998 – 2007
2007-
Sangkae Chamnanvanakij,
MD
Chulalongkorn University
Bangkok, Thailand
Director of NICU, Bangkok Thailand
1996-1999
(w/Kris Kamm, PhD)
1999 - present
Sithembiso Velaphi, MB
University of the Witwatersrand
1998-2001
Johannesburg, South Africa
Associate Professor, University of Witwatersrand 2008 - present
Director, Neonatal Medicine, Chris Hana Hospital
Head, Department of Paediatrics, Chris Hani
Baragwanath Academic Hospital
Shannon Brown, MD
Children’s Medical Center of Dallas
Private Practice, Orlando, FL
1999-2002
Deepa Nagar, MD
Medical Branch University of Texas
Private Practice
2001-2004
Mesfin Woldesenbet, MD
Harlem Hospital Center, New York
Addis Ababa University, Addis Ababa,
Ethiopia
Assistant Professor, University of
Texas Health Science Center at Houston,
Division of Neonatal-Perinatal Medicine
2002 – 2005
(w/ Jeffery Perman, M.B.)
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2005-2006
Private Practice
2006
Becky Ennis, MD
Children’s Medical Center of Dallas
Michigan State University Medical School
Assistant Professor, UT Southwestern Medical
School, Dept of Pediatrics, Division of
Neonatal-Perinatal Medicine
2003 – 2006
2006 – 2008
2008 - present
Hlwelekazi Bomela, MB
University of Witwatersrand
Senior Consultant NICU, Steve Biko
Academic Hospital
Pretoria, S. Africa
2003 - 2006
2007- present
Andi Duncan, M.D.
Children’s Medical Center of Dallas
2005 – 2008
(w/ Roy Heyne, M.D.)
2008- present
Univ. of New Mexico School of Medicine
Division of Neonatal Medicine, Director of
Follow-up Program for LBW, Assistant Professor
Completed Masters of Science in Clinical Research Nov. 2011
Darryl Miao, M.D.
Children’s Medical Center of Dallas
Private Practice, Ft Worth, TX
2005 – 2008
2008
Leo Kahn, M.D.
Pennsylvania State Medical Center at Hershey
Under Served Provider, Louisiana
2006 - 2009
2009
Joshua Frankfurt, M.D.
Univ. of Miami School of Medicine
Private practice, Dallas
2009 – 2012
2012
Michel Mikhael, MD
Univ. of Cairo School of Medicine
2009 – 2012
Orange County Children’s Hospital
2012
Dept. of Pediatrics, Univ. California Irving School
Of Medicine
Ja’Near Anderson, MD
Meharry Medical School
2010-
Anson Tang, MD
UT Southwestern Medical School
2012-
Maternal-Fetal Medicine Fellows:
Richard J. Worley, MD
UT Southwestern Medical School
Assistant Professor, OB/GYN, UT Southwestern
Professor OB/GYN, Univ of Utah Med Center
Private practice
Oscar Andujo, MD
2/17/2016
Mexico
Assistant Professor of Obstetrics and Gyn
UT Southwestern Medical School
20
1976–1978
(w/ Norman Gant, MD)
1978 – 1980
1980 - ?
1978
1999-2011
Associate Prefessor
2011 – present
Chris Hernandez, MD
UT Southwestern Medical School
Private practice, Brownsville, TX
1982 - 1984
Lowell E. Davis, MD
UT Southwestern Medical School
Professor of Obstetrics and Gynecology,
Univ. of Oregon Health Sciences Center
1985 - 1986
1986 - present
Susan M. Ramin, MD
UT Southwestern Medical School
Assistant Professor, OB/GYN, UT Southwestern
Professor and Chairman, Obstetrics and
Gynecology, Director of Maternal Fetal Medicine
UT Houston Medical Center
1989 – 1990
1990 - 1995
1995 - present
Catalina Hutuna, MD
University of Medicine and Pharmacy
Iuliu Hatieganu, Romania
Presently, Private Practice Romania
Working on PhD
2005 - 2006
Doctoral and Postdoctoral Students:
Ronald R. Magness, PhD
Postdoctoral/Univ. of Iowa
Assistant Professor, UT Southwestern
Professor of Obstetrics and Gynecology
and Animal Sciences, Director of Perinatal
Research, Univ. of Wisconsin - Madison
1984 – 1986
1986 - 1995
1995 - present
Yvonne Arens, MD, PhD.
Doctoral Student, awarded January, 2001
Rijksuniversiteit Limburg, Maastricht,
The Netherlands; PhD awarded January, 2001
Assistant Professor, Medical Genetics,
Maastricht University
1995 - 1998
ZhenZhen Shan, MD, PhD
Research Fellow
Tongji Medical University
Wuhan, China
1997-1998
Katelyn Finch, BS
Doctoral student, UTSWMS
Deborah Clegg, PhD
2011 –
Caracus, Venezuela
1975 - 1976
Auckland, New Zealand
Univ of Auckland Medical School,
Dept of Medicine
1979 – 1982
Fellow, Endocrinology
2003 – 2006
Miscellaneous:
Georgio Gabriele, MD
Raymond P. Naden, MD
Jennifer Dyer, MD
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2003- present
1986 - 1992
UT Southwestern Medical Center
Assistant Professor, Ohio State
University Medical Center, Division of
Endocrinology
(w/Dana Hardin, MD)
Poonan Panjwani, M.D.
Fellow, Pediatric Cardiology
UT Southwestern Medical Center
Assistant Professor, UTSWMS, Division of
Cardiology
2007-2010
(w/ C. Ramaciotti, MD)
Debra Weinberger, M.D.
Masters Program, Clinical and Translational
2008-2010
Science Award
(w/ Emily Tobey, PhD, Callier)
UT Southwestern Medical Center
Assistant Professor, Dept Otolaryngology and
Pediatrics
Lina Chalak, M.D.
Masters Program, Clinical and Translational
Science Award
UT Southwestern Medical Center,
Assistant Professor, Dept of Pediatrics
K23 recipient, June 2012
2008 - 2011
(w/ Pablo Sanchez, M.D.)
Arlene Davis, M.D.
Assistant Professor, Division Neonatal-Perinatal
Faculty Mentor
2011-
Uzo Ukoha
UT-SUMR Summer Program
Duke University
2012
Department of Pediatrics
UT Southwestern Medical School
Resident in Pediatrics
1987
Adrian Gresores, MD
Department of Pediatrics
UT Southwestern Medical School
Resident in Pediatrics
1991
Josh Koch, MD
Department of Pediatrics
UT Southwestern Medical School
Chief Resident in Pediatrics
2002-2005
Darryl Miao, MD
Department of Pediatrics
UT Southwestern Medical School
Resident in Pediatrics
2003-2005
Pediatric Residents:
Cindy Strand, MD
Graduate School, Integrative Biology; Qualifying Exams:
Stephanie Pierce
May, 2000
Gwyndolen Harburg
July, 2001
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Melissa McCoy
September, 2004
Nathaniel Schaffer
May, 2010
Makito Sato
May, 2011
Visiting Scientists:
Shumpei Matsuura, MD
Kyoto Univ. School of Medicine
Vice Chairman, Dept. of OB/GYN
1979 - 1980
Alfredo J. Perales, MD
Department of OB/GYN
Valencia, Spain
1981
Bernard Spitz, MD
Department of OB/GYN
Leuven, Belgium
1986 - 1987
John T. France, PhD
Department of OB/GYN
Auckland, New Zealand
1985 - 1986
Toshihiro Yoshimura, MD
Department of OB/GYN
Kumamoto, Japan
1987 – 1990
Ana Mouzinho, MD
Lisbon, Portugal
1989 – 1992
Scholarship Oversight Committees :
Liaqay Khan, MD, Division of Neonatal-Perinatal Medicine
Studies of BKCa channels in the regulation of uterine blood flow
Mentor : CR Rosenfeld, MD
2006 – 2009
Laqietha Foster, MD, Division of Neonatal-Perinatal Medicine
Studies of SPA and P4 Receptors and the onset of Parturition
Mentor : Carole Mendelson, PhD
2006 – 2009
Amanda Blair, MD, Chinni Pokala, MD and Puja Gupta, MD
Division of Hematology-Oncology
Studies of iron overload in oncology patients, VEGFR and tumor
angiogensis, and risk for fungal infection in oncology patients
2008 – 2010
Mari Afanador, MD, Division of Neonatal-Perinatal Medicine
EphrinB2 modulates distal pulmonary structure and function
Mentor: Margart A. Schwarz, MD
2009 – 2011
CURRENT ACTIVITIES:
1.
Consultant to Director of the Postdoctoral Training Program in Neonatal-Perinatal Medicine.
2.
Laboratory Research
role of estrogen in ovine pregnancy, maternal and fetal aspects.
factors influencing the magnitude and distribution of uterine blood flow in pregnancy.
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-
factors influencing maternal cardiovascular adaptation during pregnancy.
fetal hormonal and cardiovascular responses to intrauterine stress.
ontogeny of angiotensin II receptors and receptor subtypes in the fetus and pregnancy.
ontogeny of smooth muscle proteins and myosin heavy chain isoforms in the fetus and pregnancy.
regulation of blood pressure during development
3.
Clinical Research
evaluation and diagnosis of neonatal infection.
mechanisms modulating closure of the ductus arteriosus.
mechanisms regulating blood pressure after birth
fetal growth and programming
4.
Education
Lecturer, Sophomore course: “Clinical Medicine: Principles and Practice” 1995 – 2010
Director, Fellows’ Physiology Course, Neonatal-Perinatal Medicine Training Program
Director, Pediatric Department, Core Curriculum for Fellows, 2000-2004, 2007Lecturer, HUMAN BIOLOGY AND DISEASE, graduate Program in Integrative Biology
Director, Division Research Conference and Journal Club
ABSTRACTS PRESENTED AND PUBLISHED: (Last 5 yrs)
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264.
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Rosenfeld, CR, Liu X, Nagar D. Increased Expression of the Regulatory β1-Subunit of LargeConductance K+ Channels (BKCa) in Uterine Artery Vascular Smooth Muscle (VSMUa) During Ovine
Pregnancy. Society for Gynecological Investigation, March 21 – 25, 2006. (Poster Presentation)
Rosenfeld CR, Liu X. Large-Conductance K+ Channels (BKCa) are Up-Regulated in Myometrium (MYO)
During Ovine Pregnancy and Decrease Soon After Delivery. Society for Gynecological Investigation.
March 21 – 25, 2006. (Poster Presentation)
Hutanu C, Cox BE, DeSpain K, Liu X-t, Rosenfeld, CR. Developmental Changes in Ovine Carotid
Artery (CA) Function, Morphology and Protein Contents. Pediatric Academic Societies’ 2006 Annual
Meeting. April 29 – May 2, 2006. (Poster Presentation)
Dyer JS, Hardin, DS, Rosenfeld, CR. The Development of Metabolic Syndrome in Large for Gestational
Age Infants. Pediatric Academic Societies’ 2006 Annual Meeting. April 29 – May 2, 2006. (Poster
Presentation)
Bomela H, Rosenfeld CR, Bober M, Salhab W. The Prevalence and Impact of Congenital Anomalies
(CA) on Neonatal Intensive Care (NICU). Pediatric Academic Societies’ 2006 Annual Meeting. April 29
– May 2, 2006. (Poster Presentation)
Hutanu C, Cox BE, DeSpain K, Liu X-t, Rosenfeld CR. Changes in Carotid Artery Smooth Muscle
Phenotype, Function, Protein Contents and Morphology during Ovine Development. Fetal and Neonatal
Physiological Society 2006 Annual Meeting. September 17 – 20, 2006. (Oral Presentation)
Rosenfeld CR, Roy TA. Large Conductance Ca2+-Dependent K+ Channels (BKCa) Contribute to
Attenuated Uterine Vascular Responses to -Stimulation in Pregnant Sheep. 53rd Annual Meeting of Soc
for Gynecologic Investigation, March 14-17, 2007. Reprod Sciences 14:110A, 2007. (Poster Presentation)
Rosenfeld C, DeSpain K, Liu XT. Human Uterine Arteries Express an Endothelium-Derived Contracting
Factor and Large-Conductance K+ Channels that Modulate Constrictor Responses, Basal Tone and
Nitroprusside-induced Relaxation. 53rd Annual Meeting of Soc for Gynecologic Investigation, March 1417, 2007. Reprod Sciences 14:110A, 2007. (Poster Presentation)
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267.
268.
269.
270.
271.
272.
273.
274.
275.
276.
277.
278.
279.
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Miao DC, Velaphi S, Roy T, Rosenfeld CR. The Mechanisms Regulating Blood Pressure in Conscious
Newborn Sheep: Arginine Vasopressin and Metabolic Clearance Rate (MCRAVP). Pediatric Academic
Societies’ 2007 Annual Meeting. May 5 -8, 2007. (Poster Presentation)
Ennis BJ, Rosenfeld CR. Total and Free Cortisol Values are Decreased in Preterm Neonates Exposed to
Antenatal Steroids (AS). Pediatric Academic Societies’ 2007 Annual Meeting. May 5 -8, 2007. (Poster
Presentation)
Ennis BJ, Rosenfeld CR. Basal Total and Free Cortisol Measurements are Unrelated to Blood Pressure
(BP) in the First Postnatal Week in Neonates 28-32 Weeks Gestation. Pediatric Academic Societies’ 2007
Annual Meeting. May 5 -8, 2007. (Oral Presentation)
Rosenfeld CR, Hutanu C, Cox BE, DeSpain K, Liu X-t. Changes in Carotid Artery Smooth Muscle
Phenotype, Function, Protein Contents and Morphology during Ovine Development. International
Perinatal Collegium, Stockholm, Sweden July 17-20, 2007. (Oral presentation)
Ennis BJ, Roy L, Rosenfeld CR. Basal total and free cortisol measurements are unrelated to blood
pressure in the first postnatal week in neonates 28-32 weeks gestation. American Academy of Pediatrics
2007 National Conference and Exhibition, October , 2007. Klaus Award presentation.
Rosenfeld CR, Roy T. Inhibition of Uterine Vascular Nitric Oxide Synthase (NOS) Minimally Alters
Basal Uteroplacental Blood Flow (UPBFb) in Ovine Pregnancy. 54th Annual Meeting of Soc for
Gynecologic Investigation, San Diego, CA; March 27-29, 2008. Reprod Sciences 15:216A, 2008. (Poster
Presentation)
Rosenfeld CR, Liu XT Uterine Artery Large Conductance Ca+2-dependent K+ Channels (BKCa) and
Signaling Pathways are Up-Regulated During Ovine Pregnancy. 54th Annual Meeting of Soc for
Gynecologic Investigation, San Diego, CA; March 27-29, 2008. Reprod Sciences 15:217A, 2008. (Poster
Presentation)
Duncan AF, Rosenfeld CR, Morgan JS, Ahmad N, and Heyne RJ. Systolic blood pressure in very-lowbirth-weight infants exceeds a reference population in the first 3 years of life. Pediatric Academic
Societies’ 2008 Annual Meeting, Honolulu, Hawaii. May 1-6, 2008. (Poster Symposium Presentation)
Miao DC, Roy T, and Rosenfeld CR. Vascular sensitivity to angiotensin II and α-stimulation increases
after the first month postnatal in conscious newborn sheep. Pediatric Academic Societies’ 2008 Annual
Meeting, Honolulu, Hawaii. May 1-6, 2008. (Poster Presentation)
Miao DC, DeSpain K, and Rosenfeld CR. Vascular reactivity in newborn sheep is vessel and agonist
dependent. Pediatric Academic Societies’ 2008 Annual Meeting, Honolulu, Hawaii. May 1-6, 2008.
(Poster Presentation)
Ramos FG, Roy L, Koch J, Hensley G, Rosenfeld CR, Ramaciotti. Echocardiographic predictors of
ductus arteriosus in extremely-low-birth-weight infants. Am Soc Echocardiography 2008 Annual Meeting,
Toronto, Canada, JASE, May 2008; 21(5): 518. (Oral Presentation)
Khan LH, Liu X, Magness RR, Rosenfeld CR. The cGMP-PKG-dependent pathway and large
conductance Ca2+-activated K+ channels (BKCa) are up-regulated in uterine artery smooth muscle during
the ovine ovarian cycle. Society for Gynecologic Investigation, 2009 Annual Meeting. Glasgow, Scotland,
March 16-25, 2009. (Oral presentation)
Rosenfeld CR, DeSpain K, Liu X. Uterine Artery Large Conductance Ca2+-Activated K+ channels (BKCa)
Contribute to Attenuated Adrenergic Responses and Nitric Oxide-Mediated Relaxation in the Last Twothirds of Ovine Pregnancy. Society for Gynecologic Investigation, 2009 Annual Meeting. Glasgow,
Scotland, March 16-25, 2009. (Poster presentation)
Duncan AF, Heyne RJ, Morgan JS, Ahmad N, Rosenfeld CR. Systolic Blood Pressure in Very-LowBirth-Weight Infants Exceeds A Reference Population in the First 3 Yr of Life. American Academy of
Pediatrics, 2009 National Conference and Exhibition, October 17, 2009. (Klaus Award oral presentation)
25
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281.
282.
283.
284.
285.
286.
287.
288.
289.
290.
291.
292.
293.
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Rosenfeld, CR, Liu X, DeSpain K. Mechanisms Modulating Angiotensin II Sensitivity in the
Uteroplacental Vascular Bed Throughout Ovine Pregnancy. Society for Gynecologic Investigation, 2010
Annual Meeting. Orlando, FL, March 23-26, 2010. (Poster presentation)
Punjwani P, Rosenfeld CR, Ramaciotti C. Echocardiographic Prediction of Spontaneous Closure of the
Ductus Arteriosus in Neonates Less Than 30 Weeks of Gestation. American Academy of Pediatrics,
Section on Perinatal Pediatrics, 2010 National Conference and Exhibition, October 2, 2010, San
Francisco, CA (Young Investigator Travel Award; Oral presentation)
Alasmi M, Afolabi F, Rosenfeld CR. Reassessing the Neutrophil Count in the Diagnosis of Nosocomial
Infection. 6th World Conf on Pediatric Critical Care, March 13-17, 2011, Sydney, Australia. (Oral
presentation)
Rosenfeld CR, Xiao-tie L, DeSpain, K. Mechanisms modulating reduced sensitivity to angiotensin II in
the uteroplacental vascular bed of pregnant women. Society for Gynecologic Investigation, 2011 Annual
Meeting. Miami Beach, FL, March 16-19, 2011. (Oral presentation)
Rosenfeld CR, Xiao-tie L, DeSpain, K. Uterine artery function and remodeling during human pregnancy.
Society for Gynecologic Investigation, 2011 Annual Meeting. Miami Beach, FL, March 16-19, 2011.
(Poster presentation)
Frankfurt J, Duncan A, Heyne R, DeSpain K, Rosenfeld CR. Studies of Renal Function and Systolic
Blood Pressure in Preterm Very-low-birth-weight Infants at 1-3yrs Chronologic Age. South Central
Perinatal Research Meeting, Austin, TX, September 2010 (Oral Presentation). Pediatric Academic
Societies’ 2011 Annual Meeting, Denver, CO. May 1-3, 2011. (Poster)
Bergmann J, Persaud D, Rosenfeld CR. Relationship Between Childhood Obesity, Maternal Weight Gain
in Pregnancy and Fetal Growth. Pediatric Academic Societies’ 2011 Annual Meeting, Denver, CO. May
1-3, 2011. (Poster)
Alasmi M, Shade F, Rosenfeld CR. Serial Neonatal Neutrophil Counts and the Diagnosis of Late Onset
Nosocomial Infection in the Neonatal ICU. Pediatric Academic Societies’ 2011 Annual Meeting, Denver,
CO. May 1-3, 2011. (Poster)
Thankavel PP, Rosenfeld CR, Ramaciotti C. Echocardiographic prediction of spontaneous closure of the
patent ductus arteriosus in neonates <30 wks gestational age. Pediatric Academic Societies’ 2011 Annual
Meeting, Denver, CO. May 1-3, 2011. (Poster)
Rosenfeld CR, Roy T. Differential Uterine and Systemic Sensitivity to BKCa and KV Channel Inhibition
After Estradiol-17β-Induced Uterine Vasodilation in Nonpregnant Ewes. Society for Gynecologic
Investigation, 2012 Annual Meeting. San Diego, CA, March 21-23, 2012. (Poster presentation)
Wojciechowsk H, Liu X-t, Ford SP, Rosenfeld CR. Early Pregnancy Maternal Nutrient Restriction (NR)
Does Not Alter Uterine Artery (UA) Expression of Large Conductance Ca+2-Dependent K+ Channels
(BKCa). Society for Gynecologic Investigation, 2012 Annual Meeting. San Diego, CA, March 21-23,
2012. (Poster presentation)
Frankfurt J, Duncan A, Heyne R, Rosenfeld CR. Growth Patterns in Preterm Very-Low-Birth-Weight
(PT-VLBW) Infants at 1-3yrs Correlate with Elevated Serum Leptin. Pediatric Academic Societies’ 2012
Annual Meeting, Boston, MA. April 27-May 1, 2012. (Oral presentation, CTSA Child Health Research
Fellow, Travel Award)
Rosenfeld CR, DeSpain K, Baum M. Modified Carotid Artery Function at 1yr in Male Offspring of
Protein Deprived Pregnant Rats. Pediatric Academic Societies’ 2012 Annual Meeting, Boston, MA. April
27-May 1, 2012. (Poster presentation)
Ennis B, DeSpain K, Rosenfeld CR. Arginine vasopressin levels are gestational age dependent in the first
week of life and unrelated to the rise in blood pressure in neonates 24-32 weeks gestational age. Pediatric
Academic Societies’ 2012 Annual Meeting, Boston, MA. April 27-May 1, 2012. (Poster presentation)
26
294.
Mikhael, M, Brown LS, Rosenfeld CR. Do 1979 neutrophil reference ranges accurately diagnose the
presence of early onset sepsis? American Academy of Pediatrics, Section on Perinatal Pediatrics, 2012
National Conference and Exhibition, October 20, 2012, New Orleans, LA (Poster presentation)
295.
PUBLICATIONS (Peer Reviewed):
1. Rosenfeld CR. Necrotizing enterocolitis. Bulletin of the New York Academy of Medicine 47:161-172,
1971.
2. Killam AP, Rosenfeld CR, Battaglia FC, Makowski EL, Meschia G. Effect of estrogens on the uterine
blood flow of oophorectomized ewes. Am J Obstet Gynecol 115:1045-1052, 1973.
3. Rosenfeld CR, Killam AP, Battaglia FC, Makowski EL, Meschia G. Effect of estradiol-17β on the
magnitude and distribution of uterine blood flow in nonpregnant, oophorectomized ewes. Pediatr Res
7:139-148, 1973.
4. Rosenfeld CR, Eichenwald HF. The L-S ratio: Its use in the prediction of respiratory maturity in infants.
JAMA 227:610-620, 1974.
5. Morris FH, Jr., Rosenfeld CR, Resnik R, Meschia G, Makowski EL, and Battaglia FC. Growth of uterine
oxygen and glucose uptakes during pregnancy in sheep. Gynecol Invest 5:230-241, 1974.
6. Rosenfeld CR, Morris FH, Jr., Makowski EL, Meschia G, and Battaglia FC. Circulatory changes in the
reproductive tissues of ewes during pregnancy. Gynecol Invest 5:252-268, 1974.
7. Rosenfeld CR, Barton MD, Meschia G. Effects of epinephrine on distribution of blood flow in the
pregnant ewe. Am J Obstet Gynecol 124:156-163, 1976.
8. Rosenfeld CR, Morriss FH, Jr., Battaglia FC, Makowski EL, Meschia G. Effects of estradiol-17β on blood
flow to reproductive and nonreproductive tissues in pregnant ewes. Am J Obstet Gynecol 124:618-629,
1976.
9. Duenhoelter JH, Santos-Ramos R, Rosenfeld CR, Coln CD. Prenatal diagnosis of gastrointestinal tract
obstruction. Obstet Gynecol 47:618-620, 1976.
10. Rosenfeld CR, West JA. Circulatory responses to systemic infusions of norepinephrine in the pregnant
ewe. Am J Obstet Gynecol 127:376-383, 1977.
11. Rosenfeld CR. Distribution of cardiac output in ovine pregnancy. Am J Physiol 232:H231-H235, 1977.
12. Rosenfeld CR. The estimation of gestational age: An important screening technique. Medical Record
News 48:54-60, 1977.
13. Gabriele G, Rosenfeld CR, Fixler DE, Wheeler JM. Continuous airway pressure breathing with the headbox in the newborn lamb: Effects on regional blood flows. Pediatrics 59:858-864, 1977.
14. Manroe BL, Rosenfeld CR, Weinberg AG, Browne R. The differential leukocyte count in the assessment
and outcome of early-onset neonatal group B streptococcal disease. J Pediatr 91:632-637, 1977.
15. Rosenfeld CR, Worley RJ, Gant NF, Jr. Uteroplacental blood flow and estrogen production following
dehydroisoandrosterone infusion. Obstet. Gynecol 50:304-307, 1977.
16. Schreiner RL, Hurwitz RA, Rosenfeld CR, Miller W. Atrial tachyarrhythmias associated with massive
edema in the newborn. J Perinat Med 6:274-279, 1978.
17. Rosenfeld CR, Worley RJ. The effect of systemic infusions of dehydroisoandrosterone on the distribution
of uterine blood flow in ovine pregnancy. Am J Obstet Gynecol 130:385-390, 1978.
18. Rosenfeld CR, Rivera R. Circulatory responses to systemic infusions of estrone and estradiol-17β in
nonpregnant, oophorectomized ewes. Am J Obstet Gynecol 132:442-448, 1978.
19. Sanchez AM, Mize SG, Jimenez JM, Manroe BL, Rosenfeld CR, Tyson JE. Systems approach to the
evaluation of maternal and neonatal care. Proceedings 12th Hawaii Int'l Conference on System Sciences,
Selected Papers in Medical Information Processing, Vol. III, pp. 140-151, 1979.
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20. Manroe BL, Weinberg AG, Rosenfeld CR, Browne R. The neonatal blood count in health and disease. I.
Reference values for neutrophilic cells. J Pediatr 95:89-98, 1979.
21. Rosenfeld CR, Coln CD, Duenhoelter JH. Fetal cervical teratoma as a cause of polyhydramnios.
Pediatrics 64:176-179, 1979.
22. Rosenfeld CR, Worley RJ, Milewich L, Gant NF, Jr., Parker CR, Jr. Ovine fetoplacental sulfoconjugation
and aromatization of dehydorepiandrosterone. Endocrinology 106:1971-1979, 1980.
23. Rosenfeld CR, Andujo O, Johnston JM, Jimenez JM. Phosphatidic acid phosphohydrolase and
phospholipids in tracheal and amniotic fluids during normal ovine pregnancy. Pediatr Res 14:891-893,
1980.
24. Rosenfeld CR. Response of reproductive and nonreproductive tissues to 17β-estradiol during ovine
puerperium. Am J Physiol 239:E333-E339, 1980.
25. Siegel JD, McCracken GH, Jr., Threlkeld N, Milvenan B, Rosenfeld CR. Single dose penicillin
prophylaxis against neonatal Group B streptococcal infections: A controlled trial in 18,738 newborn
infants. N Engl J Med 303:769-775, 1980.
26. Morris FH, Rosenfeld CR, Crandall SS, Adcock EW III. Effects of fasting on uterine blood flow and
substrate uptake in sheep. J Nutr 110:2433-2443, 1980.
27. Rosenfeld CR, Gant NF, Jr. The chronically instrumented ewe, a model for studying vascular reactivity to
angiotensin II in pregnancy. J Clin Invest 67:486-492, 1981.
28. Furzan JA, Gabriele G, Wheeler MJ, Fixler DE, Rosenfeld CR. Regional blood flows in newborn lambs
during endotracheal continuous airways pressure and continuous negative pressure breathing. Pediatr Res
15:874-878, 1981.
29. Matsuura S, Naden RP, Gant NF, Jr., Parker CR, Jr., Rosenfeld CR. Effect of volume expansion on the
pressor response to angiotensin II in pregnant ewes. Am J Physiol 240:H908-H913, 1981.
30. Naden RP, Rosenfeld CR. Effect of angiotensin II on uterine and systemic vasculature in pregnant sheep.
J Clin Invest 68:468-474, 1981.
31. Wiriyathian S, Kaojareren S, Rosenfeld CR. Dilantin toxicity in a preterm infant: persistent bradycardia
and lethargy. J Pediatr 100:146-149, 1982.
32. Rosenfeld CR, Jackson GM. Induction and inhibition of uterine vasodilation by catechol estrogen in
oophorectomized, nonpregnant ewes. Endocrinology 110:1333-1339, 1982.
33. DeVane GW, Naden RP, Porter JC, Rosenfeld CR. Mechanism of arginine vasopressin release in the
sheep fetus. Pediatr Res 16:504-507, 1982.
34. Siegel JD, McCracken GH, Jr., Threlkeld N, DePasse BM, Rosenfeld CR. Single-dose penicillin
prophylaxis of neonatal Group-B streptococcal disease. Conclusion of a 41 month controlled trial. Lancet
1:1426-1430, 1982.
35. Lasky RE, Tyson JE, Rosenfeld CR, Priest M, Kransinski D, Heartwell S, Gant NF. Principal component
factor analyses of the Bayley Scans of Infant Development for a sample of high-risk infants and their
controls. The Merrill-Palmer Quarterly 29:25-31, 1983.
36. Wiriyathian S, Porter JC, Naden RP, Rosenfeld CR. Cardiovascular effects and clearance of arginine
vasopressin in the fetal lamb. Am J Physiol 245:E24-E31, 1983.
37. Cunningham FG, Leveno KJ, DePalma RT, Roard M, Rosenfeld CR. Perioperative antimicrobials for
cesarean delivery: Before and after cord clamping? Obstet Gynecol 62:151-154, 1983.
38. Lasky RE, Tyson JE, Rosenfeld CR, Priest M, Krasinski D, Heartwell S, Gant N. Differences on Bayley's
infant behavior record for a sample of high-risk infants and their controls. Child Develop 54:1211-1216,
1983.
39. Engle WD, Arant BS, Jr., Wiriyathian S, Rosenfeld CR. Diuresis and respiratory distress syndrome:
Physiologic mechanisms and therapeutic implications. J Pediatr 102:912-917, 1983.
40. Nielsen HC, Wiriyathian S, Rosenfeld CR, Leveno K, Garriott JC. Chlorpromazine excretion by the
neonate following chronic in utero exposure. Pediatric Pharmacology 3:1-5, 1983.
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41. Matsuura S, Naden RP, Gant NF, Jr., Parker CR, Jr., Rosenfeld CR. Effect of hypertonic saline on
vascular responses to angiotensin II in pregnancy. Am J Obstet Gynecol 147:231-240, 1983.
42. Rosenfeld CR, Jackson GM. Estrogen-induced refractoriness to the pressor effects of infused angiotensin
II. Am J Obstet Gynecol 148:429-435, 1984.
43. Naden RP, Gant NF, Jr., Rosenfeld CR. The pressor response to angiotensin II: The role of peripheral and
cardiac responses in pregnant and nonpregnant sheep Am J Obstet Gynecol 148:450-457, 1984.
44. Lasky RE, Tyson JE, Rosenfeld CR, Gant NF. Maternal-infant interactions at one-year of age in a sample
of high-risk infants and their controls. Early Human Develop 9:145-152, 1984.
45. Laptook AR, Rosenfeld CR. Chloral hydrate toxicity in a preterm infant. Pediatric Pharmacology 4:161165, 1984.
46. Engle WD, Rosenfeld CR. Neutropenia in high-risk neonates. J Pediatr 105:982-986, 1984.
47. Weinberg AG, Rosenfeld CR, Manroe BL, Browne R. The neonatal blood count in health and disease. II.
Values for lymphocytes, monocytes, and eosinophils. J Pediatr 106:462-466, 1985.
48. Naden RP, Rosenfeld CR. The role of α-receptors in estrogen-induced vasodilation in nonpregnant sheep.
Am J Physiol 248:H339-H344, 1985.
49. Naden RP, Iliya CA, Arant BS, Jr., Gant NF, Jr., Rosenfeld CR. Hemodynamic effects of indomethacin in
chronically-instrumented pregnant sheep. Am J Obstet Gynecol 151:484-494, 1985.
50. Laptook AR, Rosenfeld CR. Cerebral vascular responses to tolazoline infusions in the newborn piglet.
Early Human Develop 11:81-90, 1985.
51. Naden RP, Coultrup S, Arant BS, Jr., Rosenfeld CR. Metabolic clearance of angiotensin II in pregnant
and nonpregnant sheep. Am J Physiol 249:E49-E55, 1985.
52. Resta S, Luby JP, Rosenfeld CR, Siegel JD. Isolation and propagation of a human enteric coronavirus.
Science 229:978-981, 1985.
53. Naden RP, Rosenfeld CR. Systemic and uterine responsiveness to angiotensin II and norepinephrine in
estrogen-treated nonpregnant sheep. Am J Obstet Gynecol 153:417-425, 1985.
54. Furzan JA, Reisch J, Tyson JE, Laird P, Rosenfeld CR. Risk factors for development of hemodynamically
significant patent ductus arteriosus among inborn low-birth-weight infants. Early Human Develop 12:3948, 1985.
55. Magness RR, Osei-Boaten K, Mitchell MD, Rosenfeld CR. In vitro prostacyclin production by ovine
uterine and systemic arteries: Effects of angiotensin II. J Clin Invest 76:2206-2212, 1985.
56. Wiriyathian S, Rosenfeld CR, Arant BS, Jr., Faucher DJ, Porter JC, Engle WD. Urinary arginine
vasopressin: Pattern of excretion in the neonatal period. Pediatr Res 20:103-108, 1986.
57. Perales AJ, Naden RP, Laptook, AR, Rosenfeld CR. Fetal responses to maternal infusions of angiotensin
II. Am J Obstet Gynecol 154:195-203, 1986.
58. Strickland DM, Guzick DS, Cox K, Gant NF, Rosenfeld CR. The relationship between abortion in the
first pregnancy and development of pregnancy-induced hypertension in the subsequent pregnancy. Am J
Obstet Gynecol 154:146-148, 1986.
59. Semmler CJ, Lasky RE, Maravilla A, Dowling S, Rosenfeld CR. Brainstem auditory evoked potentials in
very-low-birth-weight neonates with intracranial hemorrhage. Early Human Develop 14:9-17, 1986.
60. Leveno KJ, Cunningham FG, Nelson N, Roark M, Williams ML, Guzick D, Dowling S, Rosenfeld CR,
Buckley A. Selected versus universal electronic fetal monitoring: A randomized study of 34,995 women. N
Engl J Med 315:615-619, 1986.
61. Magness RR, Rosenfeld CR. Systemic and uterine responses to α-adrenergic stimulation in pregnant and
nonpregnant ewes. Am J Obstet Gynecol 155:897-904, 1986.
62. Lasky RE, Tyson JE, Rosenfeld CR, Priest M, Allen D, Krasinski D, Digiacomo M, Dowling S, Gant NF.
Disappointing follow-up findings for indigent high-risk newborns. Am J Dis Child 141:100-105, 1987.
63. Faucher DJ, Lowe TW, Magness RR, Laptook AR, Porter JC, Rosenfeld CR. Vasopressin and
catecholamine secretion during metabolic acidemia in the ovine fetus. Pediatr Res 21:38-43, 1987.
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64. John ME, Simpson ER, Carr BR, Magness RR, Rosenfeld CR, Waterman MR, Mason JI. Ontogeny of
adrenal hydroxylase: Evidence for cAMP-independent gene expression. Mol Cell Endocrinol 50:263-268,
1987.
65. Parker CR, Hankins GDV, Guzick DS, Rosenfeld CR, MacDonald PC. Ontogeny of unconjugated estriol
in fetal blood and the relation of estriol levels at birth to the development of respiratory distress system.
Pediatr Res 21:386-390, 1987.
66. Andujo O, Nielsen H, Rosenfeld CR, Snyder JM. Failure to detect a stimulatory effect of estradiol-17β on
ovine fetal lung maturation. Pediatr Res 22:145-149, 1987.
67. Guzick DS, Klein VR, Tyson JE, Lasky RE, Gant NF, Rosenfeld CR. Risk factors for the occurrence of
pregnancy-induced hypertension. Clin and Exper Hyperten in Preg B6 (2):281-297, 1987.
68. France JT, Mason JI, Magness RR, Murray BA, Rosenfeld CR. Ovine placental aromatase: Studies of
activity levels, kinetic characteristics and effects of aromatase inhibitors. J Steroid Biochemistry 28:155160, 1987.
69. Faucher DJ, Laptook AR, Parker CR, Porter JC, Rosenfeld CR. Increased fetal secretion of cortisol by
arginine vasopressin. Am J Physiol 254:R410-R416, 1988.
70. Tyson JE, Lasky RE, Rosenfeld CR, Dowling S, Gant N, Jr. An analysis of potential biases in the loss of
indigent infants to follow-up. Early Human Develop 16:13-25, 1988.
71. France JT, Magness RR, Murray BA, Rosenfeld CR, Mason JI. The regulation of ovine placental steroid
17 α-hydroxylase and aromatase by glucocorticoids. Mol Endocrinol 2:193-199, 1988.
72. Magness RR, Rosenfeld CR. Mechanisms for the attenuated pressor responses to α-agonists in ovine
pregnancy. Am J Obstet Gynecol 159:252-261, 1988.
73. Gilstrap LC, Leveno KJ, Cox CM, Burris JS, Mashburn M, Rosenfeld CR. Intrapartum treatment of acute
chorioamnionitis: Impact on neonatal sepsis. Am J Obstet Gynecol 159:579-583, 1988.
74. Spitz B, Magness RR, Cox SM, Brown CEL, Rosenfeld CR: "Low-Dose Aspirin": I. Effect on
angiotensin II pressor responses and blood prostaglandin concentrations in angiotensin II-sensitive pregnant
women. Am J Obstet Gynecol 159:1035-1043, 1988.
75. Snyder JM, Kwun JE, O'Brien JA, Rosenfeld CR, Odom MJ. The concentration of the 35-kDa surfactant
apoprotein amniotic fluid from normal and diabetic pregnancies. Pediatr Res 24:728-734, 1988.
76. Parker CR, Jr., Hauth JC, Hankins GDV, Leveno K, Rosenfeld CR, Porter JC, MacDonald PC: Endocrine
maturation and lung function in premature newborns of diabetic women. Am J Obstet Gynecol 160:657662, 1989.
77. Annibale DJ, Rosenfeld CR, Kamm KE. Alterations in vascular smooth muscle contractility during ovine
pregnancy. Am J Physiol 256:H1282-H1288, 1989.
78. Magness RR, Rosenfeld CR. Local and systemic estradiol-17β: Effects on uterine and systemic
vasodilation. Am J Physiol 256:E536-E542, 1989.
79. Mason JI, France JT, Magness RR, Murry BA, Rosenfeld CR. Ovine placental steroid 17α-hydroxylase/C17, 20-lyase, aromatase and sulfatase in dexamethasone-induced and natural parturition. J Endocrinol
122:351-359, 1989.
80. Rosenfeld CR, Naden RP. Uterine and non-uterine vascular responses to angiotensin II in ovine
pregnancy. Am J Physiol 257:H17-H24, 1989.
81. Little BB, Snell LM, Gilstrap LC, Gant NF, Rosenfeld CR. Alcohol abuse during pregnancy: Changes in
frequency in a large urban hospital. Obstet Gynecol 74:547-550, 1989.
82. Parker CR, Jr., MacDonald PC, Guzick DS, Porter JC, Rosenfeld CR, Hauth JC. Prolactin levels in
umbilical cord blood of human infants: Relation to gestational age, maternal complications and neonatal
lung function. Am J Obstet Gynecol 161:795-802, 1989.
83. Wallin LA, Fawcett CP, Rosenfeld CR. Oxytocin stimulates glucagon and insulin secretion in fetal and
neonatal sheep. Endocrinology 125:2289-2296, 1989.
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84. Tyson JE, Guzick D, Rosenfeld CR, Lasky R, Gant, NF, Jimenez J, Heartwell S. Prenatal care evaluation
and cohort analyses. Pediatrics 85:195-204, 1990.
85. Magness RR, Mitchell MD, Rosenfeld CR. Uteroplacental production of eicosanoids in ovine pregnancy.
Prostaglandins 39:75-88, 1990.
86. Rosenfeld CR, Laptook AR, Jaishree N. Limited effectiveness of triple dye in preventing colonization
with methicillin-resistant staphylococcus aureus in a special care nursery. Pediat Infect Dis 9:290-291,
1990.
87. Yoshimura T, Magness RR, Rosenfeld CR. Angiotensin II and α-agonist I. Responses of ovine
fetoplacental vasculature. Am J Physiol 259:H464-H472, 1990.
88. Yoshimura T, Magness RR, Rosenfeld CR. Angiotensin II and α-agonist II. Effects on ovine fetoplacental
prostaglandins. Am J Physiol 259:H473-H479, 1990.
89. Strand C, Laptook AR, Dowling S, Campbell N, Lasky RE, Wallin LA, Maravilla AM, Rosenfeld CR.
Changing pattern of periventricular intraventricular hemorrhage in inborn low-birth-weight infants. Early
Human Develop 23:117-128, 1990.
90. Wallin LA, Rosenfeld CR, Laptook AR, Maravilla AM, Strand C, Campbell N, Dowling S, Lasky RE.
Neonatal intracranial hemorrhage: Risk factor analysis in an inborn population. Early Human Develop
23:129-137, 1990.
91. Annibale DJ, Rosenfeld CR, Stull JT, Kamm KE. Protein content and myosin light chain phosphorylation
in uterine arteries during pregnancy. Am J Physiol 259:C484-C489, 1990.
92. Little BB, Snell LM, Rosenfeld CR, Gilstrap LC, Gant NF. Failure to recognize fetal alcohol syndrome in
newborn infants. Am J Dis Child 144:1142-1146, 1990.
93. Brown CEL, Gant NF, Cox K, Spitz B, Rosenfeld CR, Magness RR. Low-dose aspirin II. Relationship of
angiotensin II pressor responses, circulating eicosanoids and pregnancy outcome. Am J Obstet Gynecol
163:1853-1861, 1990.
94. Yoshimura T, Rosenfeld CR, Magness RR. Angiotensin II and α-agonist: III. In vitro fetal-maternal
placental prostaglandins. Am J Physiol 260:E8-E13, 1991.
95. Magness RR, Rosenfeld CR, Carr BR. Protein kinase C in uterine and systemic arteries during the ovarian
cycle and pregnancy. Am J Physiol 260:E464-E470, 1991.
96. Ramin SM, Porter JC, Gilstrap LC, Rosenfeld CR. Stress hormones and acid-base status of human fetuses
at delivery. J Clin Endocrinol Metab 73:182-186, 1991.
97. Faucher DJ, Laptook AR, Porter JC, Rosenfeld CR. Effects of acute hypercapnia on maternal and fetal
release of vasopressin and catecholamines. Pediatr Res 30:368-374, 1991.
98. Mackanjee HR, Shaul PW, Magness RR, Rosenfeld CR. Angiotensin II vascular smooth muscle receptors
are not downregulated during ovine pregnancy. Am J Obstet Gynecol 165:1641-1648, 1991.
99. Corbett SS, Rosenfeld CR, Laptook AR, Risser R, Maravilla AM, Dowling S, Lasky RE. Intraobserver
and interobserver reliability in the assessment of the cranial ultrasound in very-low-birth-weight infants.
Early Human Develop 27:9-17, 1991.
100. Mouzinho A, Rosenfeld CR, Risser R. Symptomatic patent ductus arteriosus in very-low-birth-weight
babies. Early Human Develop 27:65-77, 1991.
101. Anyebuno MA, Rosenfeld CR. Chloral hydrate toxicity in a term infant. Develop Pharmacol and
Therapeutics 17:116-120, 1991.
102. Snell LM, Little BB, Knoll LA, Johnston WL, Rosenfeld CR, Gant NF. Reliability of birth certificate
reporting of congenital anomalies. Am J Perinatology 9:219-222, 1992.
103. Magness RR, Rosenfeld CR, Faucher DJ, Mitchell MD. Uterine prostaglandin production during ovine
pregnancy: Effects of angiotensin II and indomethacin. Am J Physiol 263:H188-H197, 1992.
104. Mouzinho A, Rosenfeld CR, Sanchez P, Risser R. Effect of maternal hypertension on neonatal
neutropenia and risk of nosocomial infection. Pediatrics 90:430-435, 1992.
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105. Dollar ML, Mark MS, Yelderman ML, Quinn MD, McKown RC, Eberhart RC, Rosenfeld CR.
Evaluation of a continuous thermodilution cardiac output catheter. ASAIO Journal 38:M351-M356, 1992.
106. Rosenfeld CR, Samson WK, Roy TA, Faucher DJ, Magness RR. Vasoconstrictor-induced secretion of
atrial natriuretic peptide in fetal sheep. Am J Physiol 263:E526-E533, 1992.
107. Davis LE, Magness RR, Rosenfeld CR. Role of angiotensin II and α-adrenergic receptors during
estrogen-induced vasodilation in ewes. Am J Physiol 263:E837-E843, 1992.
108. Rosenfeld CR, Cox BE, Magness RR, Shaul PW. Ontogeny of angiotensin II vascular smooth muscle
receptors in ovine fetal aorta and placental and uterine arteries. Am J Obstet Gynecol 168:1562-92, 1993.
109. Magness RR, Rosenfeld CR. Calcium modulation of endothelium-derived prostacyclin production in
ovine pregnancy. Endocrinology 132:2445-2452, 1993.
110. Hernandez C, Little BB, Dax JS, Gilstrap LC, Rosenfeld CR. Prediction of the severity of meconium
aspiration syndrome. Am J Obstet Gynecol 169:61-70, 1993.
111. Cox BE, Ipson MA, Shaul PW, Kamm KE, Rosenfeld CR. Myometrial angiotensin II receptor subtypes
change during ovine pregnancy. J Clin Invest 92:2240-2248, 1993.
112. Hoffman DR, Favor S, Uauy R, Rosenfeld CR, Magness RR. Distribution of unsaturated fatty acids in
phospholipids of arteries from nonpregnant, pregnant and fetal sheep. Prost Leuk & Essential Fatty Acids
49:907-914, 1993.
113. Magness RR, Parker CR, Rosenfeld CR. Systemic and uterine responses to chronic infusions of estradiol17β. Am J Physiol 265:E690-E698, 1993.
114. Mouzinho A, Rosenfeld CR, Sanchez PJ, and Risser R. Revised reference ranges for circulating
neutrophils in very-low-birth-weight neonates. Pediatrics 94:76-82, 1994.
115. Magness RR, Cox K, Rosenfeld CR, Gant NF. Angiotensin II metabolic clearance rate and pressor
responses in nonpregnant and pregnant women. Am J Obstet Gynecol 171:668-679, 1994.
116. Moya FR, Montes HF, Thomas VL, Mouzinho AM, Smith JF, Rosenfeld CR. Surfactant protein A and
saturated phosphatidylcholine in respiratory distress syndrome. Am J Resp and Crit Care Med 150:16721677, 1994.
117. Rosenfeld CR, Gresores A, Magness RR, Roy TA. Comparison of angiotensin II in fetal and pregnant
sheep. Metabolic clearance and vascular sensitivity. Am J Physiol 268:E237-E247, 1995.
118. Tyson JE, Kennedy KA, Broyles S, Rosenfeld CR. The small for gestational age infant: Accelerated or
delayed pulmonary maturity? Increased or decreased survival? Pediatrics 95:534-538, 1995.
119. Chern J, Kamm KE, Rosenfeld CR. Smooth muscle myosin heavy chain isoforms are developmentally
regulated in male fetal and neonatal sheep. Pediatr Res 38:697-703, 1995.
120. Cox BE, Word RA, Rosenfeld CR. Angiotensin II receptor characteristics and subtype expression in
uterine arteries and myometrium during pregnancy. J Clin Endocrinol Metab 81:49-58, 1996.
121. Magness RR, Rosenfeld CR, Hassan A, Shaul PW. Endothelial vasodilator production by uterine and
systemic arteries. I. Effects of ANG II on PGI2 and NO in pregnancy. Am J Physiol 270:H1914-H1923,
1996.
122. Cox BE, Rosenfeld CR, Kalinyak JE, Magness RR, Shaul PW. Tissue specific expression of vascular
smooth muscle angiotensin II receptor subtypes during ovine pregnancy. Am J Physiol 271: H212-H221,
1996.
123. Ipson MA, Rosenfeld CR, Magness RR, Kamm KE. Alterations in myometrial stress during ovine
pregnancy and the puerperium. Am J Physiol 271:R446-R454, 1996.
124. Turley SD, Burns DK, Rosenfeld CR, Dietschy JM. Brain does not utilize low density lipoproteincholesterol during fetal and neonatal development in the sheep. J Lipid Res 37: 1953-1961, 1996.
125. Rosenfeld CR, Cox BE, Roy T, Magness RR. Nitric oxide contributes to estrogen-induced vasodilation of
the ovine uterine circulation. J Clin Invest 98:2158-2166, 1996.
126. Engle WD, Rosenfeld CR, Mouzinho A, Risser A, Zeray F, Sanchez PJ. Circulating neutrophils in septic
preterm neonates: Comparison of two reference ranges. Pediatrics 99:1-6, 1997.
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127. Lantin-Hermoso RL, Rosenfeld CR, Yuhanna I, German Z, Chen Z, Shaul PW. Estrogen stimulates nitric
oxide synthase activity in ovine fetal pulmonary artery endothelium. Am J Physiol 273:L119-L126, 1997.
128. Kaiser JR, Cox BE, Roy TA, Rosenfeld CR. Differential development of umbilical and systemic arteries:
I. ANG II receptor subtype expression, Am J Physiol 274:R797-R807, 1998.
129. Arens Y, Chapados R, Cox BE, Kamm KE, Rosenfeld CR. Differential development of umbilical and
systemic arteries: II. Contractile proteins. Am J Physiol 274:R1815-1823, 1998.
130. Cox BE, Rosenfeld CR. Ontogeny of vascular angiotensin II receptor subtype expression in ovine
development. Pediatr Res 45:414-424, 1999.
131. Kaiser JR, Rosenfeld CR. A population-based study of congenital diaphragmatic hernia: Impact of
associated anomalies and ventilatory parameters on survival. J Pediat Surg 34:1196-1202, 1999.
132. Cox BE, Williams CE, Rosenfeld CR. Angiotensin II indirectly vasoconstricts the ovine uterine
circulation. Am J Physiol: Regulatory Integrative Comp Physiol 278:R337-R344, 2000.
133. Arens HJM, Rosenfeld CR, Kamm KE. Maturational differences between vascular and bladder smooth
muscles during ovine development. Am J Physiol: Regulatory Integrative Comp Physiol 278:R1305R1313, 2000.
134. Salhab WA, Shaul PW, Cox BE, Rosenfeld CR. Regulation of type I and type III nitric oxide synthases
by daily and acute estrogen exposure. Am J Physiol: Heart Circ Physiol 278:H2134-H2142, 2000.
135. Rosenfeld CR, White RE, Roy T, Cox BE. Calcium-activated potassium channels and nitric oxide coregulate estrogen-induced vasodilation. Am J Physiol: Heart Circ Physiol 279:H319-H328, 2000.
136. LeFlore JL, Engle WD, Rosenfeld CR. Determinants of blood pressure regulation and need for blood
pressure support in very low birth weight neonates. Early Human Develop 59:37-50, 2000.
137. Arens Y, Kamm KE, Rosenfeld CR. Maturation of ovine uterine smooth muscle during development and
the effects of parity. J Soc Gynecol Invest 7:284-90, 2000.
138. Rosenfeld CR, Cornfield DN, Roy T. Ca2+ -activated K+channels modulate basal and E2 -induced rises in
uterine blood flow in ovine pregnancy. Am J Physiol: Heart Circ Physiol 281:H22-H31, 2001.
139. Rosenfeld CR. Mechanisms regulating angiotensin II responsiveness by the uteroplacental circulation.
Am J Physiol Regulatory Integrative Comp Physiol 281:R1025-R1040, 2001.
140. Velaphi SC, Roy T, DeSpain K, Rosenfeld CR. Differential responses to systemic and local angiotensin II
infusions in postnatal sheep. Pediatr Res 52:33-341, 2002.
141. Rosenfeld CR, Roy T, Cox BE. Mechanisms modulating estrogen-induced uterine vasodilation. Vascular
Pharmacol 38:115-125, 2002.
142. Rosenfeld CR, Chen C, Roy T, Liu X. Estrogen selectively up-regulates eNOS and nNOS in reproductive
arteries by transcriptional mechanisms. J Soc Gynecol Invest 10:205-215, 2003
143. Cox BE, Roy TA, Rosenfeld CR. Angiotensin II mediates uterine vasoconstriction through α-stimulation.
Am J Physiol: Heart Circ Physiol 287: H126-H134, 2004
144. Jackson GL, Engle WD, Sendelbach DM, Vedro DA, Josey S, Vinson J, Bryant C, Hahn G, Rosenfeld
CR. Are complete blood cell counts useful in the evaluation of asymptomatic neonates exposed to
suspected chorioamnionitis? Pediatrics 113:1173-1180, 2004
145. Kaiser JR, Tilford JM, Simpson PM, Salhab WA, Rosenfeld CR. Hospital Survival of Very-Low BirthWeight Neonates from 1977 to 2000. J Perinatol 24:343-350, 2004.
146. Cox BE, Liu X, Fluharty SJ, Rosenfeld CR. Vessel specific regulation of angiotensin II receptor subtypes
during ovine development. Pediatr Res 57: 124-132, 2005.
147. Velaphi SC, Roy T, DeSpain K, Rosenfeld CR. Hemodynamic responses to systemic and hind limb
infusions of a-agonist and arginine vasopressin in conscious postnatal sheep. Pediatr Res 58:58-65, 2005.
148. Nagar D, Liu X-t, Rosenfeld CR. Estrogen regulates the β1-subunit of the BKCa channel in uterine
vascular smooth muscle. Am J Physiol: Heart Circ Physiol 289: H1417-H1427, 2005. PMID 15923308.
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149. Rosenfeld CR, Roy T, DeSpain K, Cox, BE. Large-conductance Ca2+-dependent K+ channels regulate
basal uteroplacental blood flow in ovine pregnancy. J Soc Gynecol Investig 12:402-408, 2005. PMID
15979352
150. Koch J, Hensley G, Roy L, Brown S. Ramaciotti C, Rosenfeld CR. Prevalence of Spontaneous Closure of
the Ductus Arteriosus in Neonates ≤1000 gm Birth Weight. Pediatrics 117:1113-1121, 2006.
151. Velaphi SC, DeSpain K, Roy T, Rosenfeld CR. The renin-angiotensin system in conscious newborn
sheep: metabolic clearance rate and activity. Pediatr Res, 61:681-686, 2007. P,ID 17426651
152. Hutanu C, Cox BE, Liu X-t, DeSpain K, Rosenfeld CR. Vascular development beginning in early ovine
gestation: carotid smooth muscle function, phenotype and biochemical markers. Am J Physiol Regulatory
Integrative Comp Physiol 293:323-333, 2007. PMID 17475675
153. Dyer JS, Rosenfeld CR, Rice J, Rice MS, Hardin DS. Insulin resistance in Hispanic large-for-gestationalage neonates at birth. J Clin Endocrinol Metab 92:3836-3843, 2007
154. Rosenfeld CR, Zagariya AM, Liu X-t, Willis B, Fluharty S, Vidyasagar D. Meconium increases type 1
angiotensin II receptor expression and alveolar cell death. Pediatr Res 63:251-256, 2008.
155. Woldesenbet M, Rosenfeld CR, Ramilo O, Johnson-Welch S, Perlman JM. Severe neonatal hypoxic
respiratory failure correlates with histologic chorioamnionitis and elevated concentrations of IL-6, IL-8 and
CRP. Arch Dis Child Fetal Neonatal Ed. 93:F413-F417, 2008 (Published online Jan 11, 2008).
156. Rosenfeld CR, Word RA, DeSpain K, Liu X-t. Large conductance Ca+2-activated K+ channels contribute
to vascular function in nonpregnant human uterine arteries. Reprod Sciences, 15:651-660, 2008. PMCID:
PMC2727998. PMID 18836130
157. Duncan AF, Rosenfeld CR, Morgan JS, Ahmad N, Heyne RJ. Inter-rater variability and effect of state on
blood pressure measurements in infants at 1-3 years of age. Pediatrics, 22(3):e590-594, 2008.
158. Miao DC, Velaphi SC, Roy T, DeSpain K, Rosenfeld CR. Metabolism and synthesis of arginine
vasopressin in conscious newborn sheep. Am J Physiol:Endocrinol Metab, 295(3):E672-677, 2008.
PMCID: PMC2536728. PMID 18612043.
159. Cole CR, Hansen NI, Higgins, Ziegler TR, Stoll BJ, for the Eunice Kennedy Shriver NICHD Neonatal
Research Network. Very low birth weight preterm infants with surgical short bowel syndrome: Incidence,
morbidity and mortality, and growth outcomes at 18 to 22 months. Pediatrics, 122(3):e573-82, 2008
(NICHD Network).
160. Morris BH, Oh W, Tyson JE, Stevenson DK, Phelps et al. Aggressive vs. conservative phototherapy for
infants with extremely low birth weight. N Engl J Med, 359:1885-1896, 2008 (NICHD Network).
161. Vohr BR, Tyson JE, Wright LL, Perritt RL, Poole WK. Maternal age, multiple births and extremely low
birth weight infants. J Pediatr, 154:498-503, 2009 (NICHD Network).
162. Rosenfeld CR, Liu X-t, DeSpain K. Pregnancy modifies the large conductance Ca2+-activated K+ channel
expression and cGMP-dependent signaling pathway in uterine vascular smooth muscle. Am J Physiol:
Heart Circ Physiol. 296: H1878-H1887, 2009. PMCID: PMC2716109. PMID 19470517
163. Bhandari V, Finer NN, Ehrenkranz RA, Saha S, Das A, Walsh MC, Engle WA, VanMeurs KP; Eunice
Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.
Synchronized nasal intermittent positive-pressure ventilation and neonatal outcomes. Pediatrics,
124(2):517-526, 2009 (NICHD Network).
164. Hintz SR, Bann CM, Ambalavanan N, Cotten CM, Das A, Higgins RD; Eunice Kennedy Shriver National
Institute of Child Health and Human Development Neonatal Research Network. Predicting time to hospital
discharge for extremely preterm infants. Pediatrics, 125(1):e146-54, 2010 (NICHD Network).
165. Oh W, Stevenson DK, Tyson JE, Morris BH, Ahlfors CE, Bender GJ, Wong RJ, Perritt R, Vohrs BR et al.
Influence of clinical status on the association between plasma total and unbound bilirubin and death or
adverse neurodevelopmental outcomes in extremely low birth weight infants. Acta Paediatrica, 99: 673678, 2010 (NICHD Network).
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166. D’Angio CT, Heyne RJ, O’Shea TM, Schelonka RL, Shankaran S, Duara S, Goldberg RN, Stoll BJ, Van
Meurs KP, et al. Heptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight,
premature infants. Pediatr Infect Dis J, 29:600-606, 2010 (NICHD Network).
167. SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network. Target
ranges of oxygen saturation in extremely preterm infants. NEJM, 362:1959-1969, 2010 (NICHD
Network).
168. SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network. Early CPAP
versus surfactant in extremely preterm infants. NEJM, 362:1970-1979, 2010 (NICHD Network).
169. Rich WD, Auten KJ, Gantz MG, Hale EC, Hensman AM, Newman NS, Finer NN and for the NICHD
Neonatal Research Network. Antenatal consent in the SUPPORT Trial: Challenges, costs and
representative enrollment. Pediatrics, 126: e215-e221, 2010 (NICHD Network).
170. Ramos FG, Rosenfeld CR, Roy L, Koch J, Ramaciotti C. Echocardiographic predictors of a symptomatic
patent ductus arteriosus in extremely-low-birth-weight neonates. J Perinatol, 30: 535-539, 2010.
171. Khan L, Rosenfeld CR, Liu X, Magness RR. Regulation of the cGMP-cPKG pathway and largeconductance Ca2+-activated K+ channels uterine arteries during the ovine ovarian cycle. Am J Physiol
Endocrin Metabol, 298: E222-E228, 2010. PMCID: PMC2822482. PMID 19920217
172. Ang JY, Lua JL, Asmar BI, Shankaran S, Heyne RJ, Schelonka RL, Das A, Li L, Jackson DM, Higgins
RD, D'Angio CT and for the NICHD Neonatal Research Network. Nasopharyngeal carriage of
Streptococcus pneumoniae in very low-birth-weight infants after administration of heptavalent
pneumococcal conjugate vaccine. Arch Pediatr Adolesc Med. Dec;164(12):1173-5, 2010 (NICHD
Network).
173. Boghossian NS, Hansen NI, Bell EF, Stoll BJ, Murray JC, Laptook AR, Shankaran S, Walsh MC, Das A,
Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development
Neonatal Research Network. Survival and morbidity outcomes for very low birth weight infants with Down
syndrome. Pediatrics. 126(6):1132-40, 2010 (NICHD Network).
174. Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, Hale EC, Newman NS, Schibler K,
Carlo WA, Kennedy KA, Poindexter BB, Finer NN, Ehrenkranz RA, Duara S, Sánchez PJ, O'Shea TM,
Goldberg RN, Van Meurs KP, Faix RG, Phelps DL, Frantz ID 3rd, Watterberg KL, Saha S, Das A, Higgins
RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal
Research Network. Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research
Network. Pediatrics. 126(3):443-56, 2010 (NICHD Network).
175. Duncan AF, Heyne RJ, Morgan JS, Ahmad N, Rosenfeld CR. Elevated blood pressure in very-low-birthweight infants in the first 3 years of life. Pediatr Nephrol, 26:1115-1121, 2011.
176. Shankaran S, Pappas A, McDonald SA, Laptook AR, Bara R, Ehrenkranz RA, Tyson JE, Goldberg R,
Donovan EF, Fanaroff AA, Das A, Poole WK, Walsh M, Higgins RD, Welsh C, Salhab W, Carlo WA,
Poindexter B, Stoll BJ, Guillet R, Finer NN, Stevenson DK, Bauer CR and for the NICHD Neonatal
Research Network. Predictive value of an early amplitude integrated electroencephalogram and neurologic
examination. Pediatrics. Jul;128(1):e112-20, 2011 (NICHD Network).
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177. Laughon MM, Langer JC, Bose CL, Smith PB, Ambalavanan N, Kennedy KA, Stoll BJ, Buchter S,
Laptook AR, Ehrenkranz RA, Cotten CM, Wilson-Costello DE, Shankaran S, Van Meurs KP, Davis AS,
Gantz MG, Finer NN, Yoder BA, Faix RG, Carlo WA, Schibler KR, Newman NS, Rich W, Das A,
Higgins RD, Walsh MC and for the NICHD Neonatal Research Network. Prediction of bronchopulmonary
dysplasia by postnatal age in extremely premature infants. Am J Respir Crit Care Med. Jun
15;183(12):1715-22, 2011 (NICHD Network).
178. Hintz SR, Kendrick DE, Wilson-Costello DE, Das A, Bell EF, Vohr BR, Higgins RD and for the NICHD
Neonatal Research Network. Early-childhood neurodevelopmental outcomes are not improving for infants
born at <25 weeks' gestational age. Pediatrics. Jan;127(1):62-70, 2011 (NICHD Network).
179. Ambalavanan N, Walsh M, Bobashev G, Das A, Levine B, Carlo WA, Higgins RD; NICHD Neonatal
Research Network. Intercenter differences in bronchopulmonary dysplasia or death among very low birth
weight infants. Pediatrics. Jan;127(1):e106-16, 2011 (NICHD Network).
180. Rosenfeld CR, DeSpain K, Xiao-tie L. Defining the differential sensitivity to norepinephrine and
angiotensin II in the ovine uterine vasculature. Am J Physiol Regul,Integrat,Compar Physiol. 302: R59R67, 2012. PMC Journal – In Process. PMID: 22031783
181. Rosenfeld CR, DeSpain K, Word RA, Liu X-t. Differential sensitivity to angiotensin II and
norepinephrine in human uterine arteries. J Clin Endocrinol Metab. 97: 138-147. PMC Journal – Indexed
for MedLine. PMID: 22031522
182. Thankavel PP, Rosenfeld CR, Ramaciotti C. Echocardiographic Prediction of Ductus Arteriosus Closure
in Neonates ≤30 Weeks of Gestation. J Perinatol, In press.
183. Eckman DM, Gupta R, Rosenfeld CR, Charles SM, Mertz H, Moore LG. Pregnancy increases
Myometrial artery pressure-induced constriction via NOS- or COX- independent mechanisms. Am J
Physiol-Regul,Integrat,Compar Physiol, In press.
184. Miao D, Roy T, Rosenfeld CR. Mechanisms contributing to blood pressure regulation and angiotensin IImediated pressor responses in conscious newborn sheep. Pediatr Res, in preparation.
185. Frankfurt JA, Duncan AF, Heyne RJ, Rosenfeld CR. Renal function and systolic blood pressure in verylow-birth-weight infants at 1-3 years of age. Pediatr Nephrol, (DOI) 10.1007/s00467-012-2265-y.
186. Rosenfeld CR and Roy T. Large Conductance Ca2+-Activated and Voltage-Activated K+ Channels
Contribute to the Maintenance of Uterine Vasodilation and Blood Pressure After Estrogen Treatment.
Endocrinology, submitted.
MANUSCRIPTS IN PREPARATION:
1. Rosenfeld CR, Ramacker F, Liu X-t. Regulation of smoothelin expression in myometrium and bladder
smooth muscle during development and pregnancy.
2. Rosenfeld CR, Ramacker F, Liu X-t. Differential expression of smoothelin in vascular and bladder smooth
muscle during development.
3. Brown S, Kamm KE, Liu X-t, Rosenfeld CR. Smooth muscle maturation in ovine ductus arteriosus.
4. Rosenfeld CR, Chen T, Liu X-t, Roy T. Expression and regulation of estrogen receptor subtypes in uterine
endothelium and vascular smooth muscle.
5. Rosenfeld CR, Liu X-t, McMillan C. Fetal growth restriction causes precocious alterations in vascular
angiotensin receptor subtype expression.
6. Bomela H, Rosenfeld CR. Prevalence and effects of neonates with congenital anomalies on neonatal care in
the ICU.
7. Ennis B, Christy L, Rosenfeld CR. Antenatal steroids down regulate postnatal adrenal function in neonates
<1500 gm birth weight.
8. Afolabi F, Salhab W, Ahmad N, Rosenfeld CR. Characterization of nosocomial infection and neutrophil
responses in the neonate. Pediatrics.
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TEXTBOOK CHAPTERS:
1. Rosenfeld CR and Fixler DE. Cardiovascular changes and heart disease in pregnancy. In: Clinical
Cardiology (3): The Science and Practice of Clinical Medicine. Willerson JT and Sanders CA, Editors.
Grune and Stratton, New York, 1976, pp. 477-482.
2. Rosenfeld CR. The renin-angiotensin system and regulation of uteroplacental blood flow. In: Uterine and
Placental Blood Flow. Moawad AH and Lindheimer MD, Editors. Masson Publishing Co., Inc., New
York, 1982, pp. 133-138.
3. Rosenfeld CR, Tyson JE, and Engle MD. Neonatology. Therapy in Pediatrics. Stroder J and Eichenwald
HF, Editors. The CV Mosby Co., St. Louis, 1985.
4. Rosenfeld CR, Metze H, Fricke G, and Laptook AR. Neonatology. In: Current Therapy in Pediatrics - 2.
Eichenwald HF and Stroder J, Editors. BC Decker Incorp. Philadelphia, 1989, Neonatal hypoglycemia pp.
38-40, Periventricular-intraventricular Hemorrhage pp. 46-49, Intrauterine growth retardation pp 50-54,
Infant of the drug addict pp. 54-56, Necrotizing enterocolitis pp. 59-62.
5. Magness RR and Rosenfeld CR. Eicosanoids and the regulation of uteroplacental hemodynamics. In:
Eicosanoids in Reproduction. MD Mitchell, Editor. CRC Press, Inc., Boca Raton, 1990, pp. 139-162.
6. Rosenfeld CR. Regulation of the Placental Circulation. In: Neonatal and Fetal Medicine - Physiology and
Pathophysiology. Polin RA and Fox W, Editors. WB Saunders Co., Philadelphia, 1992, Chapter 5, pp 5661.
7. Rosenfeld CR, et al. In: Pediatric Therapy - 3rd Edition. Eichenwald HF and Stroder J, Editors. MosbyYear Book, Inc., St. Louis, 1993. Part Two, Neonatology: Neonatal Hypoglycemia pp 28-30,
Periventricular-intraventricular Hemorrhage pp 37-40, Intrauterine Growth Retardation pp 41-44, Infant of
the Drug Addict pp 45-47, Necrotizing Enterocolitis, pp 51-53.
8. Magness RR and Rosenfeld CR. Maternal Cardiovascular Alterations during Pregnancy. In: Perinatal and
Pediatric Pathophysiology: A clinical Perspective. Gluckman PS and Heymann MA, Editors. Edward
Arnold Publisher, London, 1993, pp 532-540.
9. Rosenfeld CR. Regulation of the Placental Circulation. In: Fetal and Neonatal Physiology, 2nd Edition.
Polin RA and Fox WW, Editors. WB Saunders Co., Philadelphia, 1998, Chapter 6, pp70-77.
10. Rosenfeld CR, Regulation of the Placental Circulation, In: Fetal and Neonatal Physiology, 3rd Edition.
Polin RA, Fox WW, and Abman SH, Editors. W.B. Saunders Co., Philadelphia, 2004. Chapter 11, pp 97103.
11. Rosenfeld CR, Regulation of the Placental Circulation, In: Fetal and Neonatal Physiology, 4th Edition.
Polin RA, Fox WW, and Abman SH, Editors. W.B. Saunders Co., Philadelphia, 2004. Chapter 11. In
Press.
BOOKS:
1. The Uterine Circulation. Charles R. Rosenfeld, Editor. Perinatology Press. Ithaca, NY, 1989. Chapter VIII
pp 135-156, Chapter XII pp 208-238, and Chapter XIII, pp 239-271.
INVITED PAPERS:
1. Rosenfeld CR. Consideration of the uteroplacental circulation in intrauterine growth. Seminars in
Perinatology 8:42-51, 1984.
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2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
Rosenfeld CR, Porter JC. Arginine vasopressin in the developing fetus. In: Research in Perinatal
Medicine (IV). Perinatal Endocrinology. Albrecht E and Pepe GJ, Editors. Perinatology Press, Ithaca, NY,
pp 91-103, 1985.
Lawrence S, Rosenfeld CR. Fetal pulmonary development and abnormalities of amniotic fluid volume. In:
Seminars in Perinatal Medicine; Dynamics of Amniotic Fluid in Health and Disease, CR Rosenfeld, Guest
Editor. 10(2):142-153, 1986.
Rosenfeld CR. Hemodynamically significant patent ductus arteriosus in low-birth-weight infants: Fact or
fiction. In: Current Perinatology, Monohar Rathi, Editor. Springer-Verlag, New York, NY, pp 238-246,
1988.
Rosenfeld CR. Diagnosis of neonatal infection: Utilization of the absolute neutrophil count. In: Current
Perinatology, Monohar Rathi, Editor. Springer-Verlag, New York, NY, pp 146-156, 1988.
Lawrence S, Yomens E, Rosenfeld CR. Intrauterine growth retardation: Pediatric Aspects. In: Current
Therapy in Neonatal/Perinatal Medicine-2. NM Nelson, Editor. Decker Inc., Philadelphia, PA, pp 285288, 1990.
Magness RR, Rosenfeld CR. Eicosanoids and the regulation of uteroplacental hemodynamics. In:
Eicosanoids in Reproduction. Editor: MD Mitchell. CRC Uniscience Series, CRC Press, Inc., Boca Raton,
F, pp 139-167, 1990.
Gant NF, Spitz B, Magness RR, Cox SM, Rosenfeld CR, and Cox K. The pathophysiology of pregnancyinduced hypertension: Clues from low-dose aspirin therapy. In: The Journal of the Bellevue Obstetrical
and Gynecological Society. Editor: JR Snyder. The Bellevue Obstetrical and Gynecological Society, New
York, NY, pp 47-52, 1991.
Magness RR and Rosenfeld CR. Steroid Control of Blood Vessel Function. In: Steroid Hormones and
Uterine Bleeding, Alexander NJ and d'Arcangues C, Editors, American Association for the Advancement
of Science, Washington, DC, Chapter 10, pp 107-120, 1992.
Rosenfeld CR. Vascular aspects of the renin-angiotensin system in the fetus. In: Local Systems in
Reproduction. Serono Foundation Symposia, Magness, RR and Naftolin F (Eds), Raven Press, New York,
NY, pp 303-315, 1993.
Rosenfeld CR. Mechanisms controlling uteroplacental blood flow. Kumamoto District Journal of the
Japanese Obstetrical and Gynecological Society 38:9-16, 1994.
Rosenfeld CR. Blood pressure in low birth weight infants after dexamethasone. Commentary. Eur J
Pediatr 152:354-356, 1994.
Timmermans PBMWM, Inagami T, Saavedra JM, Ardaillou R, Rosenfeld CR, and Mendelsohn FAO.
Angiotensin receptor subtypes and their pharmacology. In: Pharmacological Sciences: Perspectives for
Research and Therapy in the Late 1990's. AC Cuello and B Collier, eds, Birkhauser Verlag, Basel,
Switzerland, pp 37-58, 1995.
Rosenfeld CR. The Dilemmas of Managed Care: How does it impact care of the high-risk pregnancy and
neonate? American Academy of Pediatrics, Perinatal Section Newsletter, 21:1-2, 1996.
Rosenfeld CR. Commentary: The Year Book of Pediatrics, Mosby - Year Book, Publisher, January 2002.
Dyer JS, Rosenfeld CR. Metabolic imprinting by prenatal, perinatal and postnatal overnutrition; A review.
In Early Life Origins of Adult Diseases. Ed. Hardy DB, Sem Reprod Med 29: 266-276, 2011.
Rosenfeld CR. Role of estrogen in the regulation of uterine blood flow. (Reproductive Sciences, In
preparation)
CASE REPORTS:
1. Kapadia V, Embers D, Wells E, Lemmler M, Rosenfeld CR. Prenatal Closure of the Ductus Arteriosus and
Maternal Ingestion of Anthocyanins. J Perinatol, 30:291-294, 2010.
2.
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LETTERS:
1.
Rosenfeld CR. Band neutrophil counts in neonates. J Pediatr 126:504-505, 1995.
Updated February 17, 2016
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39
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