Mark R. Vossler, M.D. F.A.C.C.
Eastside Cardiology Associates
12333 NE 130th Lane Suite 320
Kirkland, WA 98034
EDUCATION:
University of Rochester B.S. Biochemistry cum laude 5/85
University of Rochester School of Medicine M.D. 5/89
University of Vermont Resident in Internal Medicine 7/89-6/92
Oregon Health Sciences University Fellow in Cardiology 7/93-7/98
RESEARCH:
University of Rochester Department of Biophysics, Research Assistant 6/83-8/85.
Mentor: Ian Macara, Ph.D. Project: purification and kinetic characterization of
phosphotidyl inositol and tyrosine kinases
Radiation Effects Research Foundation, Hiroshima, Japan. Department of Cell
Biology, Student Fellow 6/86-8/86.
Mentor: Mitoshi Akiyama, M.D., Ph.D. Project: Development of immunoassays for
tumor related antigens.
Research,
growth
Studies
failure
CLINICAL:
Oregon Health Sciences University, Vollum Institute for Advanced Biomedical
Postdoctoral Fellow 7/94-6/97
Mentor: Philip Stork, M.D. Project: Studies of interaction between hormonal and
factor signal transduction cascades in the regulation of cell growth and differentiation.
Oregon Health Sciences University, Division of Cardiology 7/98-2/02 Projects: 1)
of factors regulating differentiation of muscle tissue. 2) Risk factors for renal
insufficiency following cardiac transplantation. 3) Clinical Trials in chronic heart
and transplantation.
University of Vermont/Given Health Care, Department of Internal
Instructor in Medicine/Attending Physician. 7/92-6/93.
Medicine,
Oregon Health Sciences University Department of Medicine Division of Cardiology.
Assistant Professor 7/98-1/02. Clinical Assistant Professor 2/02-present.
Eastside Cardiology Associates, Kirkland Washington: Cardiologist. 3/02-Present
Evergreen Hospital Medical Center Chronic Heart Failure Program: Medical Director
4/02 –Present.
PROFESSIONAL
SOCIETIES:
American College of Cardiology: Fellow. American College of Physicians: Member
American Medical Association. Washington State Medical Society. King County
Medical Society.
.
CLINICAL FOCUS: Chronic Heart Failure, Cardiomyopathy, Echocardiography, Nuclear Cardiology,
Diagnostic Heart Catheterization, Cardiac Biopsy.
BOARD
CERTIFICATION:
Internal Medicine September 1992.
Cardiology November1998
LICENSE:
Washington:
Oregon: MD19117
HONORS:
Elizabeth Arthur Science Award 1981.
Rochester Plan Early Selection for Medical School 1983.
cum laude University of Rochester 1985.
Charles Odoroff Summer Research Fellowship 1986.
Cardiovascular Signalling Training Grant O.H.S.U. 1995-1996.
Outstanding Abstract Award Western Society for Clinical Investigation 1996
Mentored Clinical Investigator Award, NIH 1998
Grant-in-Aid National American Heart Association 2000
MANUSCRIPTS:
Articles:
management
Vossler, M.R. , Ni, H., Toy, W., Hershberger, R., Preoperative Renal Function Predicts
Development Of Chronic Renal Insufficiency Following Orthotopic Heart
Transplantation. J Heart Lung Transplant, 2002, in press.
Hershberger RE, Ni H, Nauman DJ, Burgess D, Toy W, Wise K, Dutton D, Crispell K,
Vossler M, Everett J.
Prospective evaluation of an outpatient heart failure
program. J Card Fail. 2001(1):64-74.
Vossler, M. R.; Yao, H.; York, R.D.; Pan, M.G.; Rim, C.S.; Stork, P. J. S., cAMP
activates MAP kinase and Elk-1 through B-Raf and Rap 1-dependent pathway . Cell
1997 89, 73-82.
Vossler, M. R.; Kron, J., Impact of asthma therapy on cardiovascular disorders in the
elderly. Immunology and Allergy Clinics of North America. 1997, 17, 627-644.
Kohno, N.; Kyoizumi, S.; Tanabe, M.; Oyama, T.; Vossler, M.; Yamakido, M.;
Akiyama, M., Detection of a circulating tumor-associated antigen with a murine
monoclonal antibody LISA-101, selected by reversed indirect enzyme linked
immunosorbent assay. Cancer Research 1989, 49, 3412-3419.
Vossler, M. R.; Strausser, B. T.; Zaricznyj, C.; Coco, A.; Macara, I. G.,Tyrosyl and
phosphotidyl inositol kinases of human erythrocyte membranes. J. Cell.
Biochem. 1987, 33, 225-235.
Abstracts:
Vossler, M.R.,, Thayer, M.J., Inhibition of muscle differentiation by the cell cycle
regulatory kinases, ATR and Chk-1. FASEB symposium on Muscle Differentiation and
Development. 2000.
Vossler, M.R., Degnin, C., Thayer, M.J., The cell cycle regulatory kinase, Chk-1 inhibits
the transcriptional activity of MyoD. Cold Spring Harbor Symposium on
Transcriptional Regulation. 1999.
Vossler, M.R.; Ni, H; Toy, W; Crispell, K.A.; Hershberger, R.E.; Preoperative renal
function predicts development of chronic renal insufficiency following orthotopic
heart transplantation. American Society of Transplant Physicians 1998.
Silberbach, G.M.; Gornec, T.A., Vossler, M.; Stork, P.J.S.; Hershberger, R.E.; Roberts,
Vossler, M.R., Yao, H., York, R.D., Rim, C.R., Stork, P. J. S., The mechanism of
activation of MAP kinase by cAMP in Neuroendocrine cells, The Endocrine Society.
1996.
Vossler, M.R., Stork, P. J. S., The mechanism of activation of MAP kinase by cAMP
American Federation for Clinical Research/Western Society for Clinical Investigation.
1996.
Klein, R.F., Vossler, M.R., Carlos, A.S., Stork, P.J.S, Ethanol Inhibits MAP Kinase in
Osteoblasts, Research Society on Alcoholism. 1996.
Vossler, M.R.; Florio, T.; Huang, H.; Hershberger, R.E.; Stork, P.J.S., Sustained
Activation of MAP Kinase by cAMP is Associated with Growth Inhibition in
Pituitary Cells., The Endocrine Society. 1995.