Provided by:
Pathology and Laboratory Medicine
Grand Rounds
Academic Year 2014-2015
“Computational Pathology for Precision Cancer Diagnositcs”
June 8, 2015
12:00PM-1:00PM
Austrian Auditorium, CRB
Andrew H. Beck, M.D, Ph.D
Assistant Professor of Pathology, Harvard Medical School
Director of Biomedical Informatics, Cancer Research Institute, Beth Israel Deaconess Cancer
Center
Director of the Molecular Epidemiology Research Lab, Beth Israel Deaconess Medical Center
Target Audience
This program has been designed for departmental/institutional faculty, fellows and residents in the medical specialties
of anatomic pathology, neuropathology, laboratory medicine, and transfusion medicine.
Series Educational Objectives
After completing this activity, participants should be able to:
 Review biomedical research as it relates to the pathologic basis of disease
 Distinguish timely topics in modern science and medicine
 Discuss current thinking about topics in pathology and laboratory medicine
Session Educational Objectives
After completing this activity, participants should be able to:
 Review the central role of the pathologist and computational methods for precision cancer medicine
 Discuss the Importance of the integration of molecular and morphological data for guiding precision cancer
medicine
 Discuss case studies in Computational Pathology to: predict breast cancer patient survival, predict diagnosis
in pre-invasive breast neoplasia, and validate large-scale epithelial-stromal co-expression networks in breast
cancer.
Accreditation
The Perelman School of Medicine at the University of Pennsylvania is accredited by the Accreditation Council for
Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation of Credit
The Perelman School of Medicine at the University of Pennsylvania designates this live activity for a maximum of 1 AMA
PRA Category 1 Credit ™. Physicians should claim only the credit commensurate with the extent of their participation in
the activity.
Acknowledgement of Commercial Support*
NONE
For more information, please contact
Marla Knob
215-746-5772
Marla2@mail.med.upenn.edu
Check your CME online at www.penncmeonline.com
Disclosure of Relevant Financial Relationships and Unapproved Uses of Products
It is policy at the Perelman School of Medicine at the University of Pennsylvania for individuals who are in a position to
control the content of an educational activity to disclose to the learners all relevant financial relationships that they have
with any commercial interest that provides products or services that may be relevant to the content of this continuing
medical education activity. For this purpose we consider relationships of the person involved in the CME activity to
include financial relationships of a spouse or partner.
The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from
involvement in CME, but rather to ensure that Penn CME-certified activities promote quality and safety, are effective in
improving medical practice, are based on valid content, and are independent of control from commercial interests and
free of commercial bias. Peer review of all content was conducted for all faculty presentations whose disclosure
information provided to the Penn Office of CME was found to contain relationships that created a conflict of interest
relative to the topic of their presentation. In addition, all faculty were instructed to provide balanced, scientifically
rigorous and evidence-based presentations.
The staff in the Office of CME at the Perelman School of Medicine at the University of Pennsylvania, Mila Kostic,
Director of CME and the peer reviewer Zalman Agus, MD, Associate Dean for CME, have disclosed that they have
no relevant financial relationships with any commercial interests related to the content of this educational activity.
The following individuals have disclosed that they have no relevant financial relationships with any commercial interests
related to the content of this educational activity:
PLANNING COMMITTEE MEMBER NAME
TAKU KAMBAYASHI, MD, PHD
KATHLEEN MONTONE, MD
PRESENTER NAME
Andrew H. Beck, MD. PhD.
The following individuals have reported the listed relevant financial relationships with commercial interests related to
the content of this educational activity.
PLANNING COMMITTEE MEMBER NAME NAME OF COMMERCIAL INTEREST
RELATIONSHIP
WARREN PEAR, MD
PFIZER, AMGEN
STOCK HOLDINGS
ASTELLAS PHARMA
SPOUSE HONORARIUM
PRESENTER NAME
NAME OF COMMERCIAL INTEREST
RELATIONSHIP
Relevant Financial Relationships: Financial relationships are those relationships in which the individual benefits by receiving a salary,
royalty, intellectual property rights, consulting fee, honoraria, ownership interest (e.g., stocks, stock options or other ownership
interest, excluding diversified mutual funds), or other financial benefit. Financial benefits are usually associated with roles such as
employment, management position, independent contractor (including contracted research), consulting, speaking and teaching,
membership on advisory committees or review panels, board membership, and other activities from which remuneration is received
or expected
DISCLOSURE OF UNAPPROVED USES OF PRODUCTS
PRESENTER NAME
PRODUCT
INVESTIGATIONAL AND/OR OFF-LABEL USE