THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH POSITION DESCRIPTION POSITION TITLE: Postdoctoral Fellow DIVISION / DEPARTMENT: Infection & Immunity REPORTS TO: Professor Ivo Mueller POSITIONS REPORTING TO THIS ONE: DATE: 13 January 2014 PRIMARY OBJECTIVES: This position is based with the Division of Infection & Immunity but on fulltime secondment to the Vector Borne Disease Unit of the PNG Institute of Medical Research in Madang (PNGIMR), Papua New Guinea. In collaboration with overseas partners, the Mueller lab is conducting large-scale epidemiological and entomological studies to gain an in-depth understanding of transmission P. falciparum and P. vivax malaria in 3 non-Africa settings. The Entomologist /Vector Biologist will be responsible for the vector related research in Papua New Guinea. This will include the conduct of membrane feeding of P. vivax and P. falciparum infected blood samples to colony-reared mosquitoes to determine study the relationships between density and genetic complexity of gametocytes in a blood meal and its infectivity to the mosquito host. Molecular approaches will be required to identify the frequency of sexual recombination in the mosquito midgut in order to quantify potential genetics bottlenecks in the transmission process. In addition to direct project-related activities, the Entomologist /Vector Biologist will be expected to lead the small entomology/vector biology team at the PNGIMR and will be given the opportunity to develop his/her own research projects in collaboration with PNGIMR scientists. The position will thus require close collaboration with junior PNG scientists including the training and mentoring of PhD and MSc students in Papua New Guinea. KEY RELATIONSHIPS / INTERACTIONS: •Prof. Ivo Mueller, Lab Head, Infection & Immunity Unit •Dr Leanne Robinson, Head, Vector Borne Disease Unit, PNGIMR •Prof. Alan Cowman, Division Head, Infection & Immunity Unit •Prof. Peter Siba, Director, PNGIMR KEY CHALLENGES: Work independently and take on responsibility for study conduct Set up and supervise membrane feeding studies in a field setting Collaborate with scientist with variable levels of training and different cultural background Combine entomological and molecular technique FREEDOM TO ACT: • Conduct project related activities in accordance to protocol and instructions by project PIs • Supervise the activities of the PNG IMR entomology unit accordance to guidance by the IMR Head of Vector Borne Disease Unit KNOWLEDGE & EXPERIENCE REQUIREMENTS: •PhD in (medical) entomology or vector biology •Experience in vector transmission experiments •Familiarity with mosquito membrane feeding assays •Experience in mosquito colony maintenance •Experience in (basic) molecular biology •Interest in field-based research •Ability to work independently •Ability to work collaboratively with WEHI colleagues and overseas collaborators KEY ACCOUNTABILITIES KEY RESPONSIBILITIES MAJOR ACTIVITIES Project related research activities Assistance to PNG IMR entomology section OUTCOMES / PERFORMANCE MEASURES Conduct membrane feeding experiment on field samples Research is conducting in accordance with the protocol using colony reared mosquitoes and timelines of the project Molecular diagnosis and genotyping of P. falciparum and P. vivax transmission/ mosquito stages (ie gametocytes, oozysts & sporozoites) Maintenance of an Anopheline breeding colony at the PNGIMR. Coordinate the collection of clinical samples from symptomatic and asymptomatic Plasmodium spp. carrier with local field teams Assist the Head of Vector Borne Disease Unit at the PNGIMR with the management and supervision of the PNGIMR entomology unit in Madang Contribute to training in statistics for post-graduate students at PNG Institute of Medical Research The PNG IMR entomology units received adequate support to conduct its routine activities Junior PNG IMR scientists are trained and mentored KEY ACCOUNTABILITIES KEY RESPONSIBILITIES Occupational Health and Safety MAJOR ACTIVITIES Comply with Institute Health and Safety Policies and Procedures Take reasonable care of own safety and the safety of others around Use Personal Protective Equipment (PPE) and safety devices appropriately Report all hazards, incidents and injuries Attend training programs as documented in individual training needs matrices OUTCOMES / PERFORMANCE MEASURES Safe work practices followed PPE worn when required Attendance at training programs Effective implementation of required Controls Reduction in injuries