Supplementary References

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Supplementary References:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
WormBase WS130. (2003).
Duerr, J. S., Gaskin, J. & Rand, J. B. Identified neurons in C. elegans coexpress
vesicular transporters for acetylcholine and monoamines. Am J Physiol Cell
Physiol 280, C1616-22 (2001).
Alfonso, A., Grundahl, K., Duerr, J. S., Han, H. P. & Rand, J. B. The
Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine
transporter. Science 261, 617-9 (1993).
Song, H. et al. Expression of a putative vesicular acetylcholine transporter
facilitates quantal transmitter packaging. Neuron 18, 815-26 (1997).
Nehrke, K. A reduction in intestinal cell pHi due to loss of the Caenorhabditis
elegans Na+/H+ exchanger NHX-2 increases life span. J Biol Chem 278, 4465766 (2003).
McKay, S. J. et al. Gene expression profiling of cells, tissues, and developmental
stages of the nematode C. elegans. Cold Spring Harb Symp Quant Biol 68, 159-69
(2003).
Jun, K. et al. Ablation of P/Q-type Ca(2+) channel currents, altered synaptic
transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit. Proc
Natl Acad Sci U S A 96, 15245-50 (1999).
Catterall, W. A. Structure and regulation of voltage-gated Ca2+ channels. Annu
Rev Cell Dev Biol 16, 521-55 (2000).
Maryon, E. B., Coronado, R. & Anderson, P. unc-68 encodes a ryanodine receptor
involved in regulating C. elegans body-wall muscle contraction. J Cell Biol 134,
885-93 (1996).
Galante, M. & Marty, A. Presynaptic ryanodine-sensitive calcium stores
contribute to evoked neurotransmitter release at the basket cell-Purkinje cell
synapse. J Neurosci 23, 11229-34 (2003).
Mathews, E. A. et al. Critical residues of the Caenorhabditis elegans unc-2
voltage-gated calcium channel that affect behavioral and physiological properties.
J Neurosci 23, 6537-45 (2003).
Schafer, W. R., Sanchez, B. M. & Kenyon, C. J. Genes affecting sensitivity to
serotonin in Caenorhabditis elegans. Genetics 143, 1219-30 (1996).
Berger, A. J., Hart, A. C. & Kaplan, J. M. G alphas-induced neurodegeneration in
Caenorhabditis elegans. J Neurosci 18, 2871-80 (1998).
Frerking, M. & Nicoll, R. A. Synaptic kainate receptors. Curr Opin Neurobiol 10,
342-51 (2000).
Bessou, C., Giugia, J. B., Franks, C. J., Holden-Dye, L. & Segalat, L. Mutations
in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and
suggest a link with cholinergic transmission. Neurogenetics 2, 61-72 (1998).
Banks, G. B., Fuhrer, C., Adams, M. E. & Froehner, S. C. The postsynaptic
submembrane machinery at the neuromuscular junction: requirement for rapsyn
and the utrophin/dystrophin-associated complex. J Neurocytol 32, 709-26 (2003).
Lin, X., Qadota, H., Moerman, D. G. & Williams, B. D. C. elegans PAT6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in
vivo. Curr Biol 13, 922-32 (2003).
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
Olski, T. M., Noegel, A. A. & Korenbaum, E. Parvin, a 42 kDa focal adhesion
protein, related to the alpha-actinin superfamily. J Cell Sci 114, 525-38 (2001).
Fuhrmann, J. C. et al. Gephyrin interacts with Dynein light chains 1 and 2,
components of motor protein complexes. J Neurosci 22, 5393-402 (2002).
Featherstone, D. E., Davis, W. S., Dubreuil, R. R. & Broadie, K. Drosophila
alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release. J
Neurosci 21, 4215-24 (2001).
Furukawa, K. et al. The actin-severing protein gelsolin modulates calcium
channel and NMDA receptor activities and vulnerability to excitotoxicity in
hippocampal neurons. J Neurosci 17, 8178-86 (1997).
Star, E. N., Kwiatkowski, D. J. & Murthy, V. N. Rapid turnover of actin in
dendritic spines and its regulation by activity. Nat Neurosci 5, 239-46 (2002).
Dityatev, A. et al. Polysialylated neural cell adhesion molecule promotes
remodeling and formation of hippocampal synapses. J Neurosci 24, 9372-82
(2004).
Umemori, H., Linhoff, M. W., Ornitz, D. M. & Sanes, J. R. FGF22 and its close
relatives are presynaptic organizing molecules in the mammalian brain. Cell 118,
257-70 (2004).
Peng, H. B., Baker, L. P. & Chen, Q. Induction of synaptic development in
cultured muscle cells by basic fibroblast growth factor. Neuron 6, 237-46 (1991).
Crump, J. G., Zhen, M., Jin, Y. & Bargmann, C. I. The SAD-1 kinase regulates
presynaptic vesicle clustering and axon termination. Neuron 29, 115-29 (2001).
Kishi, M., Pan, Y. A., Crump, J. G. & Sanes, J. R. Mammalian SAD Kinases Are
Required for Neuronal Polarization. Science 307, 929-32 (2005).
Konietzko, U. et al. Pim kinase expression is induced by LTP stimulation and
required for the consolidation of enduring LTP. Embo J 18, 3359-69 (1999).
Chan, S. F. & Sucher, N. J. An NMDA receptor signaling complex with protein
phosphatase 2A. J Neurosci 21, 7985-92 (2001).
Raymond, C. R., Redman, S. J. & Crouch, M. F. The phosphoinositide 3-kinase
and p70 S6 kinase regulate long-term potentiation in hippocampal neurons.
Neuroscience 109, 531-6 (2002).
Parnas, D., Haghighi, A. P., Fetter, R. D., Kim, S. W. & Goodman, C. S.
Regulation of postsynaptic structure and protein localization by the Rho-type
guanine nucleotide exchange factor dPix. Neuron 32, 415-24 (2001).
Ferguson, S. S. Receptor tyrosine kinase transactivation: fine-tuning synaptic
transmission. Trends Neurosci 26, 119-22 (2003).
Moresco, E. M. & Koleske, A. J. Regulation of neuronal morphogenesis and
synaptic function by Abl family kinases. Curr Opin Neurobiol 13, 535-44 (2003).
Lackner, M. R., Nurrish, S. J. & Kaplan, J. M. Facilitation of synaptic
transmission by EGL-30 Gqalpha and EGL-8 PLCbeta: DAG binding to UNC-13
is required to stimulate acetylcholine release. Neuron 24, 335-46 (1999).
Aravamudan, B. & Broadie, K. Synaptic Drosophila UNC-13 is regulated by
antagonistic G-protein pathways via a proteasome-dependent degradation
mechanism. J Neurobiol 54, 417-38 (2003).
Ikeda, M. et al. PLC beta 4-independent Ca2+ rise via muscarinic receptors in the
mouse suprachiasmatic nucleus. Neuroreport 11, 907-12 (2000).
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
Hewes, R. S., Snowdeal, E. C., 3rd, Saitoe, M. & Taghert, P. H. Functional
redundancy of FMRFamide-related peptides at the Drosophila larval
neuromuscular junction. J Neurosci 18, 7138-51 (1998).
Lin, J. W. et al. Distinct molecular mechanisms and divergent endocytotic
pathways of AMPA receptor internalization. Nat Neurosci 3, 1282-90 (2000).
Man, H. Y. et al. Regulation of AMPA receptor-mediated synaptic transmission
by clathrin-dependent receptor internalization. Neuron 25, 649-62 (2000).
Jacob, T. C. & Kaplan, J. M. The EGL-21 carboxypeptidase E facilitates
acetylcholine release at Caenorhabditis elegans neuromuscular junctions. J
Neurosci 23, 2122-30 (2003).
Ann, K., Kowalchyk, J. A., Loyet, K. M. & Martin, T. F. Novel Ca2+-binding
protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis. J Biol
Chem 272, 19637-40 (1997).
Walent, J. H., Porter, B. W. & Martin, T. F. A novel 145 kd brain cytosolic
protein reconstitutes Ca(2+)-regulated secretion in permeable neuroendocrine
cells. Cell 70, 765-75 (1992).
Renden, R. et al. Drosophila CAPS is an essential gene that regulates dense-core
vesicle release and synaptic vesicle fusion. Neuron 31, 421-37 (2001).
Zito, K., Knott, G., Shepherd, G. M., Shenolikar, S. & Svoboda, K. Induction of
spine growth and synapse formation by regulation of the spine actin cytoskeleton.
Neuron 44, 321-34 (2004).
Pellis-van Berkel, W. et al. Requirement of the Caenorhabditis elegans RapGEF
pxf-1 and rap-1 for epithelial integrity. Mol Biol Cell 16, 106-16 (2005).
Manabe, T. et al. Regulation of long-term potentiation by H-Ras through NMDA
receptor phosphorylation. J Neurosci 20, 2504-11 (2000).
Schade, M. A., Reynolds, N. K., Dollins, C. M. & Miller, K. G. Mutations That
Rescue the Paralysis of Caenorhabditis elegans ric-8 (Synembryn) Mutants
Activate the G{alpha}s Pathway and Define a Third Major Branch of the
Synaptic Signaling Network. Genetics 169, 631-49 (2005).
Reynolds, N. K., Schade, M. A. & Miller, K. G. Convergent, RIC-8-Dependent
G{alpha} Signaling Pathways in the Caenorhabditis elegans Synaptic Signaling
Network. Genetics 169, 651-70 (2005).
Renden, R. B. & Broadie, K. Mutation and activation of Galpha s similarly alters
pre- and postsynaptic mechanisms modulating neurotransmission. J Neurophysiol
89, 2620-38 (2003).
Roberts, A. J. et al. Mice lacking 5-HT receptors show specific impairments in
contextual learning. Eur J Neurosci 19, 1913-22 (2004).
Koelle, M. R. & Horvitz, H. R. EGL-10 regulates G protein signaling in the C.
elegans nervous system and shares a conserved domain with many mammalian
proteins. Cell 84, 115-25 (1996).
Jia, K., Chen, D. & Riddle, D. L. The TOR pathway interacts with the insulin
signaling pathway to regulate C. elegans larval development, metabolism and life
span. Development 131, 3897-906 (2004).
Fritz, J. L. & VanBerkum, M. F. Regulation of rho family GTPases is required to
prevent axons from crossing the midline. Dev Biol 252, 46-58 (2002).
54.
55.
56.
57.
58.
59.
60.
61.
62.
63.
64.
65.
66.
67.
68.
69.
70.
71.
72.
Tian, X. et al. Developmentally regulated role for Ras-GRFs in coupling NMDA
glutamate receptors to Ras, Erk and CREB. Embo J 23, 1567-75 (2004).
Lonart, G. et al. Phosphorylation of RIM1alpha by PKA triggers presynaptic
long-term potentiation at cerebellar parallel fiber synapses. Cell 115, 49-60
(2003).
Horikawa, H. P., Kneussel, M., El Far, O. & Betz, H. Interaction of synaptophysin
with the AP-1 adaptor protein gamma-adaptin. Mol Cell Neurosci 21, 454-62
(2002).
Charych, E. I. et al. The brefeldin A-inhibited GDP/GTP exchange factor 2, a
protein involved in vesicular trafficking, interacts with the beta subunits of the
GABA receptors. J Neurochem 90, 173-89 (2004).
Gengyo-Ando, K. et al. The C. elegans unc-18 gene encodes a protein expressed
in motor neurons. Neuron 11, 703-11 (1993).
Weimer, R. M. et al. Defects in synaptic vesicle docking in unc-18 mutants. Nat
Neurosci 6, 1023-30 (2003).
Pevsner, J., Hsu, S. C. & Scheller, R. H. n-Sec1: a neural-specific syntaxinbinding protein. Proc Natl Acad Sci U S A 91, 1445-9 (1994).
Hata, Y., Slaughter, C. A. & Sudhof, T. C. Synaptic vesicle fusion complex
contains unc-18 homologue bound to syntaxin. Nature 366, 347-51 (1993).
Kohn, R. E. et al. Expression of multiple UNC-13 proteins in the Caenorhabditis
elegans nervous system. Mol Biol Cell 11, 3441-52 (2000).
Richmond, J. E., Davis, W. S. & Jorgensen, E. M. UNC-13 is required for
synaptic vesicle fusion in C. elegans. Nat Neurosci 2, 959-64 (1999).
Betz, A. et al. Functional interaction of the active zone proteins Munc13-1 and
RIM1 in synaptic vesicle priming. Neuron 30, 183-96 (2001).
Aravamudan, B., Fergestad, T., Davis, W. S., Rodesch, C. K. & Broadie, K.
Drosophila UNC-13 is essential for synaptic transmission. Nat Neurosci 2, 965-71
(1999).
Zhen, M. & Jin, Y. The liprin protein SYD-2 regulates the differentiation of
presynaptic termini in C. elegans. Nature 401, 371-5 (1999).
Wyszynski, M. et al. Interaction between GRIP and liprin-alpha/SYD2 is required
for AMPA receptor targeting. Neuron 34, 39-52 (2002).
de Hoop, M. J. et al. The involvement of the small GTP-binding protein Rab5a in
neuronal endocytosis. Neuron 13, 11-22 (1994).
Staunton, J., Ganetzky, B. & Nonet, M. L. Rabphilin potentiates soluble Nethylmaleimide sensitive factor attachment protein receptor function
independently of rab3. J Neurosci 21, 9255-64 (2001).
Shirataki, H. et al. Rabphilin-3A, a putative target protein for smg p25A/rab3A
p25 small GTP-binding protein related to synaptotagmin. Mol Cell Biol 13, 20618 (1993).
Ostermeier, C. & Brunger, A. T. Structural basis of Rab effector specificity:
crystal structure of the small G protein Rab3A complexed with the effector
domain of rabphilin-3A. Cell 96, 363-74 (1999).
Nonet, M. L. et al. Caenorhabditis elegans rab-3 mutant synapses exhibit impaired
function and are partially depleted of vesicles. J Neurosci 17, 8061-73 (1997).
73.
74.
75.
76.
77.
78.
79.
80.
81.
82.
83.
84.
85.
86.
87.
88.
89.
90.
91.
Sudhof, T. C. The synaptic vesicle cycle: a cascade of protein-protein
interactions. Nature 375, 645-53 (1995).
Iwasaki, K. & Toyonaga, R. The Rab3 GDP/GTP exchange factor homolog AEX3 has a dual function in synaptic transmission. Embo J 19, 4806-16 (2000).
Chetkovich, D. M. et al. Postsynaptic targeting of alternative postsynaptic
density-95 isoforms by distinct mechanisms. J Neurosci 22, 6415-25 (2002).
Nonet, M. L. Visualization of synaptic specializations in live C. elegans with
synaptic vesicle protein-GFP fusions. J Neurosci Methods 89, 33-40 (1999).
Nonet, M. L., Saifee, O., Zhao, H., Rand, J. B. & Wei, L. Synaptic transmission
deficits in Caenorhabditis elegans synaptobrevin mutants. J Neurosci 18, 70-80
(1998).
Miller, K. G. et al. A genetic selection for Caenorhabditis elegans synaptic
transmission mutants. Proc Natl Acad Sci U S A 93, 12593-8 (1996).
Fergestad, T. & Broadie, K. Interaction of stoned and synaptotagmin in synaptic
vesicle endocytosis. J Neurosci 21, 1218-27 (2001).
Koushika, S. P. et al. A post-docking role for active zone protein Rim. Nat
Neurosci 4, 997-1005 (2001).
Wang, Y., Okamoto, M., Schmitz, F., Hofmann, K. & Sudhof, T. C. Rim is a
putative Rab3 effector in regulating synaptic-vesicle fusion. Nature 388, 593-8
(1997).
Rosahl, T. W. et al. Essential functions of synapsins I and II in synaptic vesicle
regulation. Nature 375, 488-93 (1995).
Turner, K. M., Burgoyne, R. D. & Morgan, A. Protein phosphorylation and the
regulation of synaptic membrane traffic. Trends Neurosci 22, 459-64 (1999).
Iwasaki, K., Staunton, J., Saifee, O., Nonet, M. & Thomas, J. H. aex-3 encodes a
novel regulator of presynaptic activity in C. elegans. Neuron 18, 613-22 (1997).
Tanaka, M. et al. Role of Rab3 GDP/GTP exchange protein in synaptic vesicle
trafficking at the mouse neuromuscular junction. Mol Biol Cell 12, 1421-30
(2001).
Zhao, Y., Hegde, A. N. & Martin, K. C. The ubiquitin proteasome system
functions as an inhibitory constraint on synaptic strengthening. Curr Biol 13, 88798 (2003).
Speese, S. D., Trotta, N., Rodesch, C. K., Aravamudan, B. & Broadie, K. The
ubiquitin proteasome system acutely regulates presynaptic protein turnover and
synaptic efficacy. Curr Biol 13, 899-910 (2003).
Liao, E. H., Hung, W., Abrams, B. & Zhen, M. An SCF-like ubiquitin ligase
complex that controls presynaptic differentiation. Nature 430, 345-50 (2004).
Juo, P. & Kaplan, J. M. The anaphase-promoting complex regulates the
abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans.
Curr Biol 14, 2057-62 (2004).
van Roessel, P., Elliott, D. A., Robinson, I. M., Prokop, A. & Brand, A. H.
Independent regulation of synaptic size and activity by the anaphase-promoting
complex. Cell 119, 707-18 (2004).
Nguyen, M., Alfonso, A., Johnson, C. D. & Rand, J. B. Caenorhabditis elegans
mutants resistant to inhibitors of acetylcholinesterase. Genetics 140, 527-35
(1995).
92.
93.
94.
95.
96.
97.
98.
99.
100.
101.
102.
103.
104.
105.
106.
107.
108.
Nonet, M. L. et al. UNC-11, a Caenorhabditis elegans AP180 homologue,
regulates the size and protein composition of synaptic vesicles. Mol Biol Cell 10,
2343-60 (1999).
Hosono, R. & Kamiya, Y. Additional genes which result in an elevation of
acetylcholine levels by mutations in Caenorhabditis elegans. Neurosci Lett 128,
243-4 (1991).
Rual, J. F. et al. Toward improving Caenorhabditis elegans phenome mapping
with an ORFeome-based RNAi library. Genome Res 14, 2162-8 (2004).
Fraser, A. G. et al. Functional genomic analysis of C. elegans chromosome I by
systematic RNA interference. Nature 408, 325-30 (2000).
Kamath, R. S. et al. Systematic functional analysis of the Caenorhabditis elegans
genome using RNAi. Nature 421, 231-7 (2003).
Brenner, S. The genetics of Caenorhabditis elegans. Genetics 77, 71-94 (1974).
Lackner, M. R., Nurrish, S. J. & Kaplan, J. M. Facilitation of synaptic
transmission by EGL-30 Gqalpha and EGL-8 PLCbeta: DAG binding to UNC-13
is required to stimulate acetylcholine release. Neuron 24, 335-46 (1999).
Kamath, R. S. et al. Systematic functional analysis of the Caenorhabditis elegans
genome using RNAi. Nature 421, 231-7 (2003).
Kamath, R. S. & Ahringer, J. Genome-wide RNAi screening in Caenorhabditis
elegans. Methods 30, 313-21 (2003).
Ihaka, R. Gentleman R: A Language for Data Analysis and Graphics. J Comput
Graph Stat 5, 299-314 (1996).
Ward, J. H. Hierarchical grouping to optimize an objective
function. Journal of the American Statistical Association 58, 236–244 (1963).
Nagai, T. et al. A variant of yellow fluorescent protein with fast and efficient
maturation for cell-biological applications. Nat Biotechnol 20, 87-90 (2002).
Colavita, A., Krishna, S., Zheng, H., Padgett, R. W. & Culotti, J. G. Pioneer axon
guidance by UNC-129, a C. elegans TGF-beta. Science 281, 706-9 (1998).
Hobert, O. et al. Regulation of interneuron function in the C. elegans
thermoregulatory pathway by the ttx-3 LIM homeobox gene. Neuron 19, 345-57
(1997).
Mello, C. C., Kramer, J. M., Stinchcomb, D. & Ambros, V. Efficient gene transfer
in C.elegans: extrachromosomal maintenance and integration of transforming
sequences. Embo J 10, 3959-70 (1991).
Alfonso, A., Grundahl, K., Duerr, J. S., Han, H. P. & Rand, J. B. The
Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine
transporter. Science 261, 617-9 (1993).
Burbea, M., Dreier, L., Dittman, J. S., Grunwald, M. E. & Kaplan, J. M. Ubiquitin
and AP180 regulate the abundance of GLR-1 glutamate receptors at postsynaptic
elements in C. elegans. Neuron 35, 107-20 (2002).
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