Introduction to Visual Agnosias How to Navigate this Tutorial Welcome to the Vision and Aging Lab’s tutorial on visual agnosias. There are several pages of information on Visual agnosias. To navigate to the next page, click the icon on the bottom of the page. To go back please click the back button on your server tab. Have fun exploring through the world if visual agnosias! Your feedback on this tutorial is important; so any questions can comments can be sent to Manpreet Rai or Dr. Donald Kline What are Visual Agnosias? Copyright 2004 by Manpreet Rai and Donald Kline, all rights reserved What are Visual Agnosias??? General Definition of Agnosia: Agnosia = “a” not + “gnosis” to know. Thus visual agnosia would therefore be the inability to know (recognize) something by looking at it (visually). History of Agnosias Although very rare, Agnosia has been around for quite some time. As early as 430 BC Thucydides said agnosia develops because of the plague. Hippocrates also mentioned symptoms of agnosias in his writings in “On Sacred Disease” Research in visual agnosias began in the field of experimental psychology when Monk observed dogs with brain lesions in 1877. Monk called agnosia “seelenblindsheit” Freud coined the term visual agnosia in 1891 as he used the term to make distinction between perception and recognition. Freud’s term is still used today, mostly as an impairment of visual form of visual object agnosias. In general it the inability to recognize or identify familiar objects or faces without having any primary visual field problems. The recognition problem is due to neurological problems in certain brain areas depending no the type of agnosia. It seems that most, if not all agnosias are acquired rather than congenital disorders in that most are caused by brain lesions due to trauma, ischaemia, tumor or carbon monoxide poisoning all of which effect higher order visual centers. Types of Agnosias Types of Agnosias Although there is no DSM-IV-TR official categorization of agnosias, the most common way of categorizations is to divide the agnosias into two main categories: the appreceptive agnosias, and associative agnosias. The Appreceptive Agnosias Appreceptive agnosias also known as visual space agnosias) is a condition in which a person has a failure of object recognition caused by impartment in the occiptotemporal vision areas with all elementary visual functions such as acuity, colour vision, and brightness discrimination still intact. Appreceptive agnosics have trouble recognizing, matching, or copying or discriminating between stimuli, since they cannot make out visual shapes. When patients do identify objects, they do so because they have made inferences about what the object might be using colour, size, texture, and reflective cues to piece together the whole object. They do not however use any shape information. Picture of coin and key chain. The patient would describe the coin as a key chain because of the contours of the trim of the coin. Appreceptive agnosias usually occur after recovery from cortical blindness caused by toxins (such as carbon monoxide poisoning). There are several subtypes of appreceptive agnosias. Please click on the subtype below obtain further information: Dorsal Simultanagnosia Visual hemi-neglect Ventral Simultanagnosia Associative Agnosia Associative agnosia is also known as visual object agnosia. This agnosia is a characterized by a variety of symptoms, but the main impairment is that of recognizing visually presented objects despite having intact visual perception of that object. There are three specific criteria to have a diagnosis of associative agnosia as presented by Farah1990). The three criteria are: 1) Difficulty recognizing a variety of visually presented objects (i.e. by naming or grouping objects together according to their semantic categories). 2) Normal recognition of a variety of objects be other senses such as touch, smell taste or when given a verbal description of it. 3) Intact elementary visual perception, enough to redraw an object an suggestively recognize it Thus from these criteria a patient may be able to replicate a drawing but still not recognize is. Thus associative agnosia is in many cases called recognition without meaning. Insert sample of what associative agnosias might draw, (with respect to object (i.e. perfect drawing, but can’t name what he/she just drew) Associative agnosia usually occurs due to brain damage ranging from the right posterior regions to the unilateral left posterior regions, and sometimes even both! There are several types of associative agnosias as well. Please click on the tabs below for further information. Prosopagnosia Colour Agnosia Treatments of Visual Agnosia Topographical agnosia Dorsal Simultanagnosia Simultanagnosia means an inability to recognize two things simultaneously. Patients with Dorsal Simultagnosia can identify some parts of an object and use that to make inferences of the whole object. Simultanagnosia was coined by Wolpert, and Luria made it more specific referring to it as a visual deficit in which only one object can be seen at a time, so an attentional problem is also a factor in this agnosia, since unattended objects are at seen at all. Doral Simultanagnosia patients cannot localize stimuli even when it is seen. It is due to damage in the bilateral parieto-occipital region of the brain. Dorsal simultanagnosia patients may be impaired in their reading and counting since theses activities involve seeing more than one thing at a time. Therefore, it may inhibit them from working in jobs that require such activities. Dorsal simultanagnosia patients also bump into objects that are close together, thus may act blind. Motion may further impair their ability to perceive objects. Thus a whole object may be perceived but not in the presence of another object, both are not perceived. Insert photo pf overlapping objects (i.e. hockey stick, hammer, flask, spoon etc). A patient with dorsal simultanagnosia will only say they see one of the items, and disregard the rest, even saying the other items do not even exist. Return to Appreceptive Agnosias page Ventral Simultanagnosia Like dorsal simultanagnosia, patients with this disorder can not identify more than on object, or objects with complex entities at a time. However, the brain region involved is the left inferior temporo-occipital regions. Ventral simultanagosics can see more than one object at a time (as seen in their ability to count scattered dots, and walk around without bumping into obstacles such as a couch and a table that are both in the same vicinity. However ventral simultanagnosic patients are mostly impaired in their ability to read, and describe complex pictures (Farah, 1990). These patients may be able to describe one aspect of a picture without having a clear understanding of the picture as a whole. Insert Picture of mountain scene, as a stimulus that patient cannot recognize the picture as a scene from the pyramids, since she fails to see the camel. Return to Apperceptive Agnosias page. Visual Hemi-Neglect Visual hemi neglect is the inability to perceive thing on a person’s left side in spatial orientation due to right parietal lobe damage. Tests such as block drawings, or drawings or designs or incomplete pictures is a sign that a patient can clearly make out the right side, but completely ignore the left side. Insert picture of a drawing that a hemineglect patient may complete (neglecting the left side) Return to Apperceptive Agnosias page Colour Agnosias In colour agnosias visual perception of colour vision, and brightness discrimination is still intact. Nevertheless, there is a severe impairment in the ability to name and distinguish between colours. Colour agnosics usually have lesions in their left occitpotemporal regions of the brain. A test to check colour agnosia may be a combination of giving names to colours, or showing a patient an incorrectly coloured object. If the patient identifies it as incorrect they may have colour agnosia. Thus a blue banana may seem perfectly normal to a colour agnosics. It is important to note however that these patients are not colour blind, slice they perform well on colour tests such as arranging hues, and passing the Ishihara plate test. A small number of colour agnosics may suffer from achromatopsia as well. Insert picture of blue banana, orange apple, and some other discolored object. Agnosics patients will identify these objects as normal. Return to Associative Agnosia Page Topographical Agnosia Topographical agnosia patients are unable to use visual cues to direct to go in a particular direction. This happens because they are unable to recognize the objects around them, which makes this agnosia fall under the associative category of agnosias. Topographical agnosia patients therefore may not be able to navigate efficiently around their own bedroom. It is important to not however that these patients have excellent topographical memory so can describe the layout of their house, or even their workplace. Topographic agnosia is due to right posterior cingulate lesions in the brain. Return to Associative Agnosias Page Prosopagnosia Prosopagnosia is probably the most well known associative agnosias being the inability to recognize faces, despite having adequate vision and intelligence. Bodmer first coined the term prosopagnosia in 1947, although cases were first reports as early as 1844. In 1962 Hecan formally defined prosopagnosia as “a failure to recognize people known to the patient on the basis of visual perception of their faces” (Lanids, 1991). This definition is still sued today, but has expanded somewhat in that it no longer limited just to faces. Prosopagnosia can also be used as a way of classifying impairments in recognizing specific types of animals (such as a bird watcher being unable to recognize specific species of birds). Sometimes a patient with prosopagnosia can recognize an expression on a face, but still cannot recognize the face as a whole. Other times a person may be able to recognize a face by recognizing the person’s voice, or identifying contours of a loved ones face. Other features such as a mole that the patient remembers may be the cue they use to recognize a person’s face. For prosopagnosia patients there is always a lesion in the right inferior-medial temporo-occipital area, however cases with bilateral lesions have been reported as well. Seven out of 14 patients with unilateral posterior artery stroke in the acute stage had prosopagnosia as well. A great example of a prosopagnosia is with Mr. P in Sacks’ study the man who mistook his wife for a hat. He could only recognize his wife by her voice, and could only recognize pictures of his family and friends through specific no-facial features, (such as military clothes that his army brother may be wearing, or a persons chipped tooth so that of his good friend bob for instance). Return to Associative Agnosias page Treatment of Visual Agnosias As one can see from the previous pages, the different visual agnosias can be very debilitating for a person, as it may hinder their day to day functioning, and even be traumatic for the people around the patient with agnosia, such as family and friends. However, since brain lesions cause all of the agnosias, there is no treatment since it is not impossible to ‘unlesion’ areas of the brain. Patients however do go on living with a decent lifestyle as there are several ways in which to cope with agnosias. To being with agnosia patients can still use cues to identify and recognize objects. Thus other senses come to be very important for agnosia patients. Take Mr. P for example, he can still carry on with his love of teaching of music, since he still has all his hearing senses in tact, thus the agnosia may hinder his ability to recognize faces, and objects, but he can still teach music. Furthermore, since agnosia patients have lost the ability to do something that they could once do very quickly, such as identify a key chain as a key chain and not anything else, making them slow down and spend some more time examining an object may help them better identify it rather than their quick glance over and reply. This slowing down when visualizing objects may take some time, but it can be seen as a rehabilitation process, in which some recognition may be slowly learned again. Again all the other taste, smell, touch, and hearing are important in this task as well. Furthermore, a patient with agnosia may benefit greatly from consistency, such as having his/her shirt and pants in the same place every morning, and having furniture in similar places all the time. Since agnosia patients have intact memory, they can fund their way around without fully recognizing an object but still get around in their job. For patients who have lost their ability to write, such is the case with appreceptive agnosics, a strategy called visual tracing may slowly help gain back some writing skills. Here patients practice tracing letters with their fingers then make eye movements to track their finger. Soon they practice writing with the finger traces, thereby learning how to write just by using eye movements that mimic the finger traces. Although there are ways of coping with having agnosias, a person must still go through a major lifestyle change. For instance they most likely are depended on someone sled to help them with getting around and about and even simple things like eating cereal with a spoon rather than a knife. Also some patients are not as lucky as Mr. P, and may have to leave their jobs if they cannot recognize their workplace, and the things around it. Mist difficult however may be the prosopagnosia where family member and friends seem like strangers. This is difficult for both the patient as well as the family members as well, since having a loved one not recognize you can be very heartbreaking. The best way to cope with this is just have patience with the agnosics. The patient can sue facials cues such as birthmarks, and moles to recognize their loved one, or they can use the sound of the loved ones voice as well to recognize them. So there are no treatments for agnosia, the best way to deal with it is to adjust your lifestyle to compensate for the lack of visual competence. More information on Visual Agnosias