Bioprospecting: governance, science, and the politics of plant collecting Cori Hayden University of Cambridge and UC Berkeley This paper charts the controversial trajectory of 'bioprospecting', or benefit-sharing agreements between pharmaceutical companies, public sector universities, and rural and indigenous communities, and it explores the implications of these agreements for the analytical project of science studies. I will discuss the pharmacological and political/regulatory dimensions of the advent of benefitsharing, with a particular emphasis on the UN Convention on Biological Diversity and contravening trade accords such as NAFTA/TLC. I will then discuss a few particular agreements in Mexico to show how scientific collecting practices themselves are transformed by the new and contested mandate of benefit-sharing, just as particular investigators' research practices prove to be crucial political sites for shaping these transnational collaborations. In this context, routine decisions about which plants to collect, or what kingdom to scan for potential value, become laced with the explosive question of who shall ‘come with’ these plants (ie, be considered a beneficiary), and on what basis. The paper argues that the rise and fall of such arrangements in Mexico and internationally marks out a distinctive challenge for the social studies of science, in particular for our understandings of how political and social relations are literally being written into bio-artifacts, and back out of them again, with enormous consequence for questions of rights, sovereignty, and the conduct of Mexican science.