1 Dr Nicoletta Charolidi Using Pioglitazone to Identify New Targets for Aneurysm Treatment - The Role of EGR1 in an Experimental Murine Model of Aortic Aneurysm 2 Dr Jennifer Stott Obligatory role of G-protein beta gamma subunits in Kv7 channel activity 3 Mr Phil Adds BONE UP ON BONES: Ancestry investigation with CRANID software 4 Miss Lu Wang Neuronal Lineage Determination of Postnatal Murine Neural Crest Stem Cells 5 Dr Christian Lambert Fine Grain Cortical Segmentation using Multiparametric Maps at 3T 6 Ms Annette Archie–Acheampong High Resolution Tractography Based Parcellation of the Human Insula in vivo 7 Ms Gloria Onwuneme Hippocampal Sub-regions Revealed Using Metaanalytic Connectivity Modeling 8 Mr Henry Simon Parcellation of the Human Thalamus in vivo using Anomalous Diffusion 9 Mr James Forrester Axonal Properties of the Corpus Callosum Characterised using Anomalous Diffusion 10 Dr Jose Antonio ARAGON-MARTIN British EL patients with novel ADAMTSL4 mutations: 2 homozygotes, 1 compound heterozygote & 1 compound heterozygote involving a splice site 11 Miss Zahra Parvar The role of gene Lin28 in the onset of puberty 12 Prof David Strachan UK BiLEVE, the first genetic study in UK Biobank, identifies novel regions associated with airway obstruction using a custom genome-wide array in 50,000 individuals 13 Miss Sabrina Waheed Bilateral hypoplasia of the femoral artery – a cadaveric case report 14 Miss Eva Zeestraten Longitudinal white matter changes in small vessel disease and cognition: a prospective study 15 Miss Bina Ram Will moving into social and affordable housing in East Village increase family physical activity levels? Evaluation of a natural experiment 16 Miss Mohani-Preet K Bajaj Patients diagnosed with COPD, who exacerbate, have greater cognitive impairment than those with worsening heart failure 17 Mr Raymond Smith The Impact of Volunteer Mentoring on Carers of People with Dementia 18 Dr Alison Kent PCV13 immunogenicity in premature infants: A comparison of 3 different primary schedules. 19 Miss Rosemary Lane Angiogenesis in Prostate Cancer 20 Dr Nidhi Sofat Patient Reported Pain By the Paindetect Questionnaire Reveals Multimodal Elements to Pain Perception in Rheumatoid Arthritis 21 Miss Natasha Clarke Screening for evidence of mild semantic impairment as a marker of underlying TDP43 neuropathology in autoimmune conditions 22 Miss Venezia Souceradjou FBN1 NEGATIVE MUTATION PATIENTS, WHAT DO YOU DO NEXT? 23 Miss Noreen Nguru The Balancing Act: Distress and Coping in Adult Intensive Care Staff 24 Ms Kayleigh Kew Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease 25 Mrs Kinga Stanczak-Mrozek Transfer of antimicrobial resistance genes between clinical MRSA by endogenous prophages 1 26 Miss Jarama Clucas The Role of Radixin in Prostate Cancer Progression 27 Miss Heather Jeffery Further investigation into KIF11 mutations causing MCLMR 28 Mr Daniel George STRUCTURAL AND FUNCTIONAL CONSEQUENCES OF ADDITIVE ANGIOGENIC STIMULI IN RAT HINDLIMB SKELETAL MUSCLE 29 Dr Vanessa Ho Mechanisms of GPR55-mediated relaxation in mouse mesenteric arteries 30 Dr Vanessa Ho Effects of perivascular fat on endothelium-dependent relaxation in young healthy rats 31 Prof Deborah Baines Glucose and lactate concentrations in ASL are modified by hyperglycaemia 32 Ms Odel Soren Enhancement of antibiotic activity against multi-drug resistant Gram-negative bacteria using novel antimicrobial peptide Novicidin as part of combination therapy 33 MISS JENNIFER SHALLOP To investigate the combination of antimicrobial peptides with existing antibiotics against multi-drug resistant clinical isolates of gram negative bacteria. 34 Mr Harry Pritchard Functional interplay of CFTR and TMEM16A channels in mesenteric artery smooth muscle. 35 Mr Christopher Huggins Elevating plasma high-density lipoproteins (HDLs) reduce experimental abdominal aortic aneurysm (AAA) – investigating the therapeutic potential 36 Miss Caroline Moussa Synergistic effect of novel compounds HT0121567 and HT013018 combined with antibiotics against Gram-negative and Gram-positive pathogenic bacteria 37 Ms Elisavet Fotiou Novel mutations in PIEZO1 can cause Hennekam Syndrome 38 Dr Nuha Alrayes Truncating mutation in intracellular phospholipase A1 gene (DDHD2) in hereditary spastic paraplegia with intellectual disability (SPG54). 39 Dr Greg Mellor THE PREVALENCE OF THE EARLY REPOLARISATION PATTERN IN YOUNG ADULTS AND ITS RELATIONSHIP WITH PHYSICAL ACTIVITY. 40 Dr Greg Mellor The Early Repolarisation pattern is independent of structural athletic remodeling in a population of young active individuals 41 Mr Martin Ashby Targeting MRSA with short antimicrobial peptides 42 Mr Andrew Walker An exploration of physiotherapists’ current practice in the management of patients with vestibular disorders experiencing anxiety 43 Miss Catherine Spilling Evidence of widespread microstructural white matter damage to network links in the brains of COPD patients 44 Dr Jogitha Selvarajah mTORC2-mediated regulation of the DNA damage response 45 Dr Leonie Wong Whole Exome Sequencing in Sudden Infant Death Syndrome Identifies a High Proportion of Putative Pathogenic and Functionally Significant Rare Variants Related to Inherited Cardiac Conditions 46 Dr Nordine Helassa A novel fluorescent sensor protein for detecting changes in airway surface liquid glucose concentration 47 Dr Nordine Helassa Development of fast calmodulin-based genetically-encoded fluorescent calcium indicators 48 Mr Philip Goff Reversal of hypopigmentation in Hermansky-Pudlak syndrome models by MC1R signalling 49 Mr Harry Greenberg Calcium-Sensing Receptors induce nitirc oxide production and IKCa channel activation to induce endothelium-dependent vasorelaxations 2 50 Dr Guang Yang Longitudinal Study for Low-Grade Gliomas (LGG) Using Advanced Multimodal MRI 51 Miss Emma Mott A Quantitative Investigation into Contrast Enhancement Levels of Abdomino-Pelvic CT Images Using a Weight-Adapted Method of Contrast Media Administration 52 Mr Yui Wan Screening of the gene PRKG1 in a British cohort of thoracic aortic aneurysm and dissection (TAAD) patients. 53 Dr Kathy Scott The combination of ∆9-tetrahydrocannabinol (THC) and cannabidiol (CBD) enhances the anticancer effects of radiation in an orthotopic murine glioma model 54 Dr Wai Liu Supernatants of tumours treated with chemotherapy can be used to alter tumour growth and development in vivo 55 Miss Ekta Vasita Phosphodiesterase 5 (PDE5) as a potential therapeutic target in small arteries of aged human brain 56 Dr Charlotte Barker Feasibility of Developing a European Paediatric Antimicrobial Pharmacokinetic/Pharmacodynamic Network Utilizing Opportunistic Sampling Strategies 57 Dr. Samira Saadoun Neuromyelitis optica IgG causes placental inflammation and fetal death in mice 58 Ms Danielle Charles What's the Risk? Effectiveness of an Exercise on Referral Stratification System 59 Dr Katie Lane Chronic Kidney Disease Serum Inhibits Transcription of CYP3A4 in a Human Hepatocyte Model. 60 Dr Dev Katarey Intrapatient variability of tacrolimus blood concentrations - acute rejection or no connection? 61 Miss Lydia Krexi Sudden cardiac death with emotional stress in young population: the importance of specialist cardiac pathological examination. 62 Miss Lydia Krexi Mitral valve prolapse and sudden cardiac death. Is there a related genetic cardiomyopathy? 63 Dr Dimitra Krexi Pulmonary hypertensive vascular changes in lungs of patients with Sudden Unexpected Death. Emphasis on congenital heart disease, Eisenmenger syndrome, post operative deaths and death during pregnancy and post partum. 64 Mr Jaskaren Kohli Markers of senescence and immortalisation: assessing value in melanoma diagnosis 65 Dr Daniel Fowler Zoledronic acid-induced targeting of tumour-associated macrophages by γδ T cells 66 Mrs Cheryl Anderson Exercise facilities for neurologically disabled populations - Perceptions from the fitness industry 67 Dr Ramanan Sivakumaran Effect of Donepezil on Cerebral Blood Flow following Aneurysmal Subarachnoid Haemorrhage - 'DASH ' Trial 68 Mr Szymon Stelter Interaction of plant-derived anti-HIV monoclonal antibody with human receptors 69 Dr. Jian Shi Stimulation of store-operated canonical transient receptor potential 1 channels requires Gq-protein, phospholipase C, and stromal interaction molecule 1 in vascular smooth muscle 70 Dr Yanushi Wijeyeratne GENETIC MODIFIERS IN CARRIERS OF THE SCN5A E1784K MUTATION WITH VARIABLE PHENOTYPIC EXPRESSION - LONG QT3 / BRUGADA SYNDROME OVERLAP DISEASE 71 Mr Phil Carver An evaluation of the use of sensor technology in establishing aquatic routes to increased physical activity: A case experience from a knowledge transfer partnership (KTP) 72 Prof. Tom Carter ROLE OF THE CYTOSKELETON IN THE REGULATION OF WEIBEL-PALADE BODY EXOCYTOSIS 3 73 Mr Isaac Phang Injured Spinal Cord Pressure Evaluation (ISCoPE) study – expansion duroplasty reduces spinal cord pressure in acute spinal cord injury 74 Dr Jogitha Selvarajah Type II topoisomerases as targets for rational drug design 75 Mr Joe Fenn Effect of BCG on γδ T cells in a non-human primate model 76 Mr Andrew Gravett Chemotherapeutic agent gemcitabine may facilitate anti-tumour immune responses by augmenting tumour visibility 77 Miss Elwira Kaminska The immune-modulatory role of Apolipoprotein E 78 Dr Vivek Chhaya Have thiopurines altered the risk of colectomy in Ulcerative Colitis – A national UK based observational study 79 Mr Dario Pacitti Development of a reagent for the isolation of Exosomes 80 Miss Michelle Levene Preliminary quantitative data for the extracted cellular and Exosomal miRNA using column and phenol based methods. 81 Dr Suman Rice Unravelling the Preantral Follicle Genome: The First Comprehensive Gene Expression Profiling Of Human Preantral Follicles. 82 Dr Paris Ataliotis The GNB1L Interactome and WNT signaling in 22q11 Deletion Syndrome 83 Dr Rhys Hewett Differences in intestinal metaplasia in Barrett’s oesophagus patients in an ethnically diverse south London population 84 Ms Jennifer Smith Open Access at SGUL 85 Mr Sandeep Bahia Aneurysm-CaRe: A Pilot Randomised Controlled Trial of Cardiac Rehabilitation versus Standard Care after Aortic Aneurysm Repair 86 Dr Rajay Narain Preventing sudden cardiac death in the young: Results form a population-based screening program in the UK 87 Dr Kate Hawkins Investigating the signalling mechanisms underlying human induced pluripotent stem cell reprogramming 88 Miss Maryam Khan Evolution in action: Do bacteriophage mediate the emergence of novel multi-resistant CA-MRSA strains via exchange of antibiotic resistance genes? 89 MIss Emma Cousins A genetic investigation of familial yellow nail syndrome 90 Miss Ruth Benson Glial Fibrillary Acidic Protein as a biomarker for neurological injury after abdominal aortic aneurysm repair 91 Mr Owen Williams Microstructural Brain Change Characterised by Diffusion Segmentation (DSEG) is related to Cognitive Decline in Cerebral Small Vessel Disease 92 Miss Jiapreet Bharj A novel transcriptional regulatory pathway in cardiac and skeletal muscle. 93 Miss Emma Sparrow The contribution of granulysin expressed by γδ T cells in dendritic cell migration 94 Bram Prins Whole genome sequencing association analyses of ECG measures 95 Mr Matt Shephard Identifying Novel Protocols for the Differentiation of Pluripotent Stem Cells to Hepatocytes 96 MISS EVMORFIA PETROPOULOU Rare and common variation in SCN10A is associated with Brugada Syndrome 97 MISS EVMORFIA PETROPOULOU Coagulopathy in Necrotising Enterocolitis: Modulation of Gene Expression Microarrays Analysis to Study Gene Expression 4 98 Miss Lorna FitzPatrick Investigating the role of LIN28 and Nuclear factor kappa B (NFκB) throughout neural specification of human pluripotent stem cells. 99 Dr Daniel Osborn Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies 100 Dr Tarek Antonios Microvascular remodelling in preeclampsia: quantifying capillary rarefaction accurately and independently predicts preeclampsia. 101 Miss Rebecca Flynn Effects of Mycobacterium tuberculosis on host cell gene expression 102 Mr Azhar Ali Cardiac and Vascular Changes in Patients with Chronic Kidney Disease Before and After Kidney Transplantation: A Prospective Study 103 Mr Reza Maroofian Mutations in KPTN cause macrocephaly, neurodevelopmental delay, and seizures. 104 Dr Mustafa Ahemd Loss of PCLO function underlies pontocerebellar hypoplasia type III 105 Mr Rajendra Raghuraman DO SOUTH ASIANS HAVE MICROCIRCULATORY REMODELLING AT BIRTH? 106 Miss Laura James-Allan Regulation of trophoblast by decidual stromal cells in first trimester pregnancies with normal and impaired spiral artery remodelling. 107 Miss Rebecca Buckley Exploring the role of decidual macrophage activation in the first-trimester of human pregnancy 108 Mr Andrea Dell'Aquila Quantification of left ventricular trabeculations complexity using fractal analysis 109 Azhar Ali Cardiac and Vascular Changes in Patients with Chronic Kidney Disease Before and After Kidney Transplantation: A Prospective Study 5