19th INTERNATIONAL SYMPOSIUM ON THE AUTONOMIC NERVOUS SYSTEM Kauai Marriott Resort & Beach Club Kauai, Hawaii October 29-November 1, 2008 Final Program WEDNESDAY, OCTOBER 29, 2008 7:30 AM-2:00 PM Satellite Symposium 5:00-7:00 PM Registration/Welcome Reception & Special Poster Session 7:00-7:15 PM Welcome - Dr. Italo Biaggioni Advances in Pathophysiology Chairs: Horacio Kaufmann & Irwin Schatz 7:15-7:30 PM Hypotension and cognitive impairment in the elderly IJ Schatz, K Masaki, G Fujikami, R Chen, D Laurin, R Abbott, G Ross, H Petrovitch, L White, P Blanchette, L Launer Honolulu, HI, USA 7:30-7:45 PM SDS/MSA Research Award Prospective differentiation of multiple system atrophy from Parkinson’s disease A Lipp, P Sandroni, JE Ahlskog, RD Fealey, TL Gehrking, SD Weigand, DM Sletten, JA Gehrking, KK Nickander, W Singer, DM Maraganore, GK Wenning, CM Shults, PA Low Rochester, MN, USA 7:45-8:00 PM CCHS: Distribution of PHOX2B mutations in a large cohort DE Weese-Mayer, CM Rand, DA Loghmanee, L Zhou, AS Kenny, LJ Jennings, EM Berry-Kravis Chicago, IL, USA 8:00-8:15 PM Neuronal source of plasma dopamine DS Goldstein, C Holmes Bethesda, MD, USA 8:15-8:30 PM Time course of changes in vasomotor sympathetic activity during normal human pregnancy 8:30-8:45 PM Q Fu, TB VanGundy, S Shibata, DL Creson, BD Levine Dallas, TX, USA Genetic markers for autonomic dysfunction in healthy children of Andean highlanders L Huicho, C Qualls, G Xing, M Rivera-Ch, JL Gamboa, A Verma, O Appenzeller Albuquerque, NM, USA THURSDAY, OCTOBER 30, 2008 7:30-8:00 AM Breakfast 8:00-8:45 AM Plenary Lecture Autonomic Clocks and Circadian Rhythms Dr. Andries Kalsbeek The Netherlands Autonomic Control of Blood Pressure in Normotensive and Hypertensive States Chairs: Mark Chapleau & Wouter Wieling 8:45-9:00 AM pH sensitive ion channels contribute to carotid body hypersensitivity in spontaneously hypertensive rats ZY Tan, Y Lu, CA Whiteis, MW Chapleau, FM Abboud Iowa City, IA, USA 9:00-9:15 AM AAS Travel Fellowship Award Spinophilin and blood pressure regulation AC da Costa-Goncalves, J Tank, R Plehm, A Diedrich, M Todiras, M Gollasch, M Wellner, M Bader, J Jordan, FC Luft, V Gross Berlin, Germany 9:15-9:30 AM Muscle sympathetic nerve activity during mental stress: responders vs. nonresponders JR Carter, CA Ray Houghton, MI, USA 9:30-9:45 AM FMS Penaz-Wesseling Travel Fellowship Award Enhancement of vestibular ocular counter-roll with subthreshold stochastic resonance galvanic stimulation MC Geraghty, BM Deegan, SJ Wood, JM Serrador Boston, MA, USA 9:45-10:00 AM Respiratory modulation and baroreflex control of heart rate after eight days in space B Verheyden, J Liu, AE Aubert Leuven, Belgium 10:00-10:15 AM Lack of evidence for nitric oxide deficiency contributing to hypertension in humans A Gamboa, LE Okamoto, A Diedrich, C Shibao, G Farley, SY Paranjape, D Robertson, I Biaggioni Nashville, TN, USA 10:15-10:30 AM Autonomic regulation of circulation profile in patients with severe left ventricle of heart myocardial hypertrophy depending on the blood pressure level TA Lubimtseva, OV Mamontov, AO Conrady, OM Moiseeva, EV Shlyakhto St. Petersburg, Russia 10:30-10:45 AM Coffee Break Advances in Autonomic Evaluation Chairs: Phillip Low & Max Hilz 10:45-11:00 AM Tonic inhibitory influence of cerebellar cortex on the 10-Hz rhythm in sympathetic nerve discharge GL Gebber, SM Barman East Lansing, MI, USA 11:00-11:15 AM Spectral analyses of cardiovascular control in spinal cord injured rats and humans VE Claydon, JA Inskip, LM Ramer, MS Ramer, AV Krassioukov Vancouver, BC, Canada 11:15-11:30 AM Evaluation of a novel non model driven assessment of cardiac autonomic activity: response to combined graded orthostatic and heat stress R Schondorf, J Benoit, M Genoulaz, MJ Lafitte Montreal, QC, Canada 11:30-11:45 AM CO2-NO axis: a novel pathway in mediating cerebrovascular vasodilatation M Masoud, H Saher, B Brenner, A Roguin, G Jacob Haifa, Israel 11:45-12:00 PM 12:00-12:15 PM 12:15-12:30 PM 12:30-2:00 PM Translating cardiac neuroimaging to clinical practice: a novel approach to neurogenic orthostatic hypotension DS Goldstein, Y Sharabi Bethesda, MD, USA The use of real-time ultrasonography in microneurography TB Curry, MJ Joyner, N Charkoudian Rochester, MN, USA Quantifying sweat gland innervation – a comparison of two novel unbiased methods CH Gibbons, BMW Illigens, R Freeman Boston, MA, USA Lunch & Poster Session I DAVID H. P. STREETEN SESSION 2:00-2:45 PM Streeten Lecture Catecholamines 101 Dr. David Goldstein Bethesda, MD, USA 2:45-3:00 PM Streeten Travel Fellowship Award The balancing act between sympathetic nerve activity and cardiac output: differences between young men and women EC Hart, N Charkoudian, BG Wallin, TB Curry, JH Eisenach, MJ Joyner Rochester, MN, USA FRIDAY, OCTOBER 31, 2008 7:00-8:30 AM Breakfast & Poster Session II 8:30-9:15 AM Plenary Lecture Pathogenesis and treatment development in transgenic mouse models of multiple system atrophy and a-synuclein accumulation Dr. Eliezer Masliah San Diego, CA, USA Diabetes and Autonomic Impairment Chairs: Felicia Axelrod & Roy Freeman 9:15-9:30 AM Sympathetic and parasympathetic outflow imbalance is involved in blood pressure increase in db/db mice AC Costa-Goncalves, J Tank, J Jordan, A Diedrich, R Plehm, FC Luft, V Gross Berlin, Germany 9:30-9:45 AM Insulin neuritis: can excessive glucose control impair autonomic function? CH Gibbons, R Freeman Boston, MA, USA 9:45-10:00 AM Anatomical and functional changes in baroreceptor afferent, central and efferent components of the baroreflex circuitry in type 1 diabetic mice (OVE26) Z Cheng, M Lin, L Li, C Huang, H Gu, B Yan Orlando, FL, USA 10:00-10:15 AM Attenuated baroreflex function in response to antecedent hypoglycemia – does this play a role in the mortality associated with rigorous control of diabetes? I Bonyhay, G Adler, E Waring, H Failing, R Freeman Boston, MA, USA 10:15-10:30 AM Loss of coupling between cerebral blood flow and blood pressure in diabetic autonomic neuropathy SJ Yeh, CC Chiu, BY Liau Taichung, Taiwan 10:30-10:45 AM Coffee Break Orthostatic Tolerance, Syncope and POTS Chairs: Giris Jacob & Maria Hopman 10:45-11:00 AM Head-up tilt induced vasoconstriction is preserved in dopamine-β-hydroxylase deficiency JT Groothuis, J Deinum, JWM Lenders, MTE Hopman Nijmegen, The Netherlands 11:00-11:15 AM A steep fall in cardiac output is the main determinant of hypotension during drug free and nitroglycerine induced orthostatic vasovagal syncope B Verheyden, J Liu, N van Dijk, BE Westerhof, T Reybrouck, AE Aubert, W Wieling Amsterdam, The Netherlands 11:15-11:30 AM Inadequate cutaneous vasoconstriction in the heat stressed human at the onset of syncopal symptoms during an orthostatic challenge CG Crandall, M Shibasaki Dallas, TX, USA 11:30-11:45 AM Role of the cholinergic system in orthostatic intolerance and cerebral blood flow response to orthostatic challenge JM Serrador, EF Waring, R Freeman Boston, MA, USA 11:45-12:00 PM Diminished diurnal variations of blood pressure in postural tachycardia syndrome K Sato, I Biaggioni, SR Raj, D Robertson, A Diedrich Nashville, TN, USA 12:00-12:15 PM Low dose propranolol is effective at decreasing orthostatic tachycardia and improves symptoms in postural tachycardia syndrome (POTS) SR Raj, I Biaggioni, BK Black, PA Harris, SY Paranjape, M Ramirez, D Robertson Nashville, TN, USA 12:15-12:30 PM One month of non-selective beta-adrenergic blockade treatment normalizes vasomotor sympathetic activity without improving symptoms during upright tilt in the postural orthostatic tachycardia syndrome Q Fu, S Shibata, TB VanGundy, DL Creson, BD Levine Dallas, TX, USA SATURDAY, NOVEMBER 1, 2008 7:00-8:30 AM Breakfast & Poster Session III Skin and Peripheral Autonomic Function Chairs: Craig Crandall & Julian Stewart 8:30-8:45 AM The cutaneous architecture of autonomic nerve fiber innervation CH Gibbons, N Wang, R Freeman Boston, MA, USA 8:45-9:00 AM Intradermal angiotensin-II administration attenuates the local cutaneous vasodilator heating response JM Stewart, I Taneja, N Raghunath, D Clarke, MS Medow Valhalla, NY, USA 9:00-9:15 AM Intradermal norepinephrine administration attenuates the local cutaneous vasodilator heating response MS Medow, I Taneja, N Raghunath, JM Stewart Valhalla, NY, USA 9:15-9:30 AM A dynamic analysis of sudomotor function in a human model of small fiber neuropathy CH Gibbons, BMW Illigens, R Freeman Boston, MA, USA 9:30-9:45 AM Quantitative sudomotor axon reflex test (QSART) in HIV-infected patients with antiretroviral therapy (ART)-associated neuropathy 9:45-10:15 AM 10:15-10:30 AM M Boger, T Hulgan, A Peltier Nashville, TN, USA Business Meeting Coffee Break Novel Approaches to Treatment Chairs: David Robertson & Michael Joyner 10:30-10:45 AM Enhancement of CGRP receptor signaling: a novel approach to improving autonomic regulation in normal and hypertensive states R Sabharwal, Z Zhang, HM Stauss, FM Abboud, AF Russo, MW Chapleau Iowa City, IA, USA 10:45-11:00 AM Tilt training increases the vasoconstrictor reserve in patients with neurally mediated syncope evoked by head-up tilt testing B Verheyden, H Ector, AE Aubert, T Reybrouck Leuven, Belgium 11:00-11:15 AM The effect of nitroglycerine and desmopressin on blood pressure, nocturnal polyuria and morning orthostatic tolerance in the hypertension of autonomic failure LE Okamoto, A Gamboa, C Shibao, BK Black, SR Raj, D Robertson, I Biaggioni Nashville, TN, USA 11:15-11:30 AM Acute sympathetic vasomotor tone reduction with electrical carotid sinus stimulation in patients with refractory hypertension K Heusser, J Tank, A Diedrich, S Engeli, J Menne, S Eckert, CGJ Sweep, N Krueger, G Franke, G Stoffels, FC Luft, J Jordan Hannover, Germany 11:30-11:45 AM Ongoing clinical trials of droxidopa. An interim update H Kaufmann, C Mathias, R Freeman, P Low, D Robertson and the Droxidopa Study Group New York, NY, USA 11:45-7:00 PM Free Time 7:00-10:00 PM Presidential Dinner SPECIAL POSTER SESSION – Cardiac Sympathetic Neuroimaging Wednesday, October 29, 2008 5:00-7:00 PM Poster #S1 Differential diagnostic value of normal uptake but increased 123I-MIBG washout in Parkinsonism Y Uchiyama, M Momose, C Kondo, K Kusakabe, M Iwata, S Uchiyama Tokyo, Japan Poster #S2 123I-meta-iodobenzylguanidine scintigraphy is a useful diagnostic tool to differentiate early phase of Lewy body disease from other movement disorders T Takeda, S Uchiyama Tokyo, Japan Poster #S3 123I-MIBG scintigraphy in PSP, CBD and IPD M Yoshita, D Noto, K Takahashi, M Yamada Poster #S4 Poster #S5 Poster #S6 Poster #S7 Poster #S8 Poster #S9 Poster #S10 Poster #S11 Poster #S12 Poster #S13 Kanazawa, Japan Myocardial sympathetic degeneration correlates with olfactory function in Parkinson’s disease M Iijima, M Osawa, M Momose, M Suzuki, S Uchiyama Tokyo, Japan MIBG myocardial scintigraphy in the diagnosis of dementia J Nunomura, M Nishie, A Arai, Y Miki, M Baba Aomori, Japan 123I-metaiodobenzylguanidine myocardial scintigraphy and susceptibility weightedimaging of the substantia nigra in patients with PD T Maeda, K Nagata, H Toyoshima, T Kinoshita Akita, Japan Longitudinal observation of MIBG myocardial scintigraphy in patients with multiple system atrophy H Nagayama, M Ueda, M Hamamoto, K Tsukamoto, Y Katayama Tokyo, Japan Preclinical investigation of 11C-phenethylguanidines as radiotracers for quantifying cardiac sympathetic nerve density with PET DM Raffel, Y-W Jung, G Gu, RA Koeppe, P Sherman, C Quesada Ann Arbor, MI, USA PET measurement of cardiac and nigrostriatal denervation in parkinsonian syndromes DM Raffel, RA Koeppe, R Little, C-N Wang, S Liu, L Junck, M Heumann, S Gilman Ann Arbor, MI, USA Importance of renal function of cardiac iodine-123 metaiodobenzylguanidine scintigraphy for predicting prognosis of heart disease patients T Furuhashi, M Moroi, H Hase, T Kunimasa, R Nakazato, H Fukuda, K Sugi Tokyo, Japan Marked reduction of cardiac 123I-MIBG uptake in REM sleep behavior disorder compared with Parkinson’s disease K Kashihara, T Imamura, M Ohno, S Kawada Okayama, Japan Evaluation of Parkinson’s disease and related disorders using cardiac MIBG scintigraphy K Marumoto, K Ichikawa, R Yamada, H Kikuchi, M Nakashita, K Matsumoto, Y Kageyama Hyogo, Japan Translating cardiac neuroimaging to clinical practice: a novel approach to neurogenic orthostatic hypotension DS Goldstein, Y Sharabi Bethesda, MD, USA POSTER SESSION I Thursday, October 30, 2008 12:30-2:00 PM Advances in Autonomic Physiology Chairs: Fetnat Fouad-Tarazi & Qi Fu Poster #1 Alpha adrenergic contribution to the resting autonomic support of arterial blood pressure in healthy men versus women AP Dutoit, JA Schmitt, EC Hart, N Charkoudian, BG Wallin, TB Curry, JH Eisenach, MJ Joyner Rochester, MN, USA Poster #2 Influences of gender on the interaction between sympathetic nerve traffic and central adiposity J Tank, K Heusser, A Diedrich, D Hering, FC Luft, A Busjahn, K Narkiewicz, J Jordan Hannover, Germany Poster #3 Nitric oxide tonically modulates heart rate in humans A Gamboa, LE Okamoto, A Diedrich, B Black, SR Raj, D Robertson, I Biaggioni Nashville, TN, USA Poster #4 Effects of atrial natriuretic factor on renal sympathetic nerve activity in anaesthetized rats APM Yusof, S Farah Wahida, MY Nurul Hasnida Penang, Malaysia Poster #5 Cardiovagal and cardiac sympathetic contributions to respiratory sinus arrhythmia R Schondorf, J Benoit, M Genoulaz, M Lafitte Montreal, QC, Canada Poster #6 Progesterone alters Schwann cell growth in culture KA Pollard, T Chelimsky, LN Berti-Mattera Cleveland, OH, USA Poster #7 The pressor effect of water: mechanism and location of action. J McHugh, NR Keller, M Appalsamy, A Diedrich, J Jordan, SR Raj, D Robertson Nashville, TN, USA Poster #8 Heart rate variability during the Valsalva maneuver partially explains ethnic differences in blood pressure in a rural population in Hawaii A Grandinetti, DC Chow, D Sletten, P Low Honolulu, HI, USA Poster #9 ACE genotype is associated with prolonged QTc in individuals with decreased heart rate variability during paced breathing A Grandinetti, DC Chow, D Sletten, P Low Honolulu, HI, USA Advances in Laboratory Evaluation Chair: André Diedrich Poster #10 Reduced heart-rate variability during the Valsalva maneuver is associated with decreased FEV1 and FVC A Grandinetti, DC Chow, R Hoshide, E Fernandez, J Orr, B Brooks, EK Tam Honolulu, HI, USA Poster #11 Heart rate variability during autonomic blockade AB Mehlsen, J Mehlsen Copenhagen, Denmark Poster #12 Use of wavelet analysis of heart rate variability in the differentiation of normal and emphysema subjects while at rest and during exercise MN Bartels, AM Petrock, SS Reisman, RH Rockland, JA Downey, RE DeMeersman New York, NY, USA Poster #13 Analysis of cardiopulmonary dynamics using wavelet analysis methods MN Bartels, AM Petrock, SS Reisman, RH Rockland, JA Downey, RE DeMeersman New York, NY, USA Poster #14 Oral leak size influences hemodynamic responses to the Valsalva maneuver R Khurana, D Mittal, A MacArthur, NH Dubin Baltimore, MD, USA Advances in Pathophysiology Chairs: Vera Novak & Thomas Chelimsky Poster #15 Heart rate variability in adults exposed to different levels of volcanic air pollution D Chow, A Grandinetti, E Fernandez, J Orr, B Brooks, A Sutton, T Elias, R Hoshide, E Tam Honolulu, HI, USA Poster #16 Up-regulation of hemeoxygenase 1 in an animal model of takotsubo cardiomyopathy T Ueyama, Y Tsuruo, K Yoshida, H Kimura Wakayama, Japan Poster #17 Poster #18 Poster #19 Poster #20 Poster #21 Poster #22 Poster #23 Poster #24 Poster #25 Poster #26 Markers of disease in familial dysautonomia; is there a phenotype in carriers? G Gold-von Simson, M Leyne, J Mull, LM Rolnitzky, JD Goldberg, D Berlin, H Kaufmann, FB Axelrod, SA Slaugenhaupt New York, NY, USA Glucose homeostasis in younger patients with neurogenic orthostatic hypotension JL Gilden, S Ubhayakar, K Bhesaniya, S Cherian, J Downs, J McAfee, S Tucker, T Valika, R Lakhani North Chicago, IL, USA Autonomic testing in patients with interstitial cystitis E Heller, K McNeeley, CA Buffington, T Chelimsky Cleveland, OH, USA Co-morbid autonomic disorders in interstitial cystitis E Heller, K McNeeley, A Alshekhlee, G Chelimsky, T Chelimsky Cleveland, OH, USA Validation of a survey of self-reported symptoms for the screening and diagnosis of complex regional pain syndrome JD Miles, T Chelimsky Cleveland, OH, USA Demographics and comorbidities of patients with complex regional pain syndrome JD Miles, A Alshekhlee, T Chelimsky Cleveland, OH, USA Autonomic dysfunction in Allgrove syndrome RW Shields, Jr Cleveland, OH, USA On-admission autonomic nervous cardiac tone predicts the success of myocardial reperfusion in acute ST elevation myocardial infarction R Dragu, D Adam, M Kapeliovich, H Hammerman, G Jacob Haifa, Israel Microinjection of NMDA in the RVLM produces an enhanced increase in RSNA in rats with heart failure KP Patel, X Liu, H Zheng Omaha, NE, USA Prevalence of OH in a nursing home and rehabilitation population before and after initiation of a standardized treatment protocol SL Mader, D Hickam, K Adams, K James, W Schutzer Portland, OR, USA POSTER SESSION II Friday, October 31, 2008 7:00-8:30 AM Orthostatic Tolerance and Syncope Chairs: Satish Raj & Benjamin Levine Poster #27 Role of head-up tilt and carotid massage in patients with unexplained syncope referred to an autonomic unit J Freitas, E Azevedo, R Santos, C Abreu-Lima, MJ Maciel Porto, Portugal Poster #28 Diagnostic value of co-morbid conditions in neurally mediated syncope (NMS) IT Jarjour, LK Jarjour Houston, TX, USA Poster #29 The hemodynamic pattern of the progressive orthostatic hypotension syndrome C Podoleanu, R Maggi, D Oddone, A Solano, P Donateo, F Croci, E Carasca, C Ginghina, M Brignole Targu Mures, Romania The validity of “empty heart syndrome” in the pathogenesis of neurocardiogenic syncope H Wang, C Kobzowicz, M Yerkey, R Christian, F Jaeger, F Fouad-Tarazi Cleveland, OH, USA Poster #31 Orthostatic syndromes are associated by sympathetic withdrawal as demonstrated by non-invasive autonomic monitoring RR Arora, J Colombo Chicago, IL, USA Poster #32 Orthostatic tolerance predictors in patients with recurrent syncope C Schroeder, J Tank, K Heusser, A Busjahn, A Diedrich, FC Luft, J Jordan Berlin, Germany Poster #33 Beta2-adrenoceptor mediated syncope during upright tilt in humans Q Fu, S Shibata, TB VanGundy, DL Creson, BD Levine Dallas, TX, USA Poster #34 Neuroendocrine changes during head-up tilt and syncope J Mehlsen, AM Lebech, A Kjaer Frederiksberg, Denmark Poster #35 Was Sir Thomas Lewis right? LJ Norcliffe-Kaufmann, MJ Tellez, A Voustianiouk, S Lenina, H Kaufmann New York, NY, USA Poster #36 FMS Penaz-Wesseling Travel Fellowship Award Initial orthostatic hypotension of the young is attenuated by static handgrip DA Clarke, I Taneja, MS Medow, JM Stewart Valhalla, NY, USA Poster #37 Effect of posture on the autonomic responses to an inspiratory apnea I Taneja, MS Medow, PJ Fadel, DA Clarke, JM Stewart Valhalla, NY, USA Postural Tachycardia Syndrome Chair: Jens Jordan Poster #38 Is postural tachycardia syndrome (POTS) associated with syncope? KJ McNeeley, A Ojha, E Heller, G Chelimsky, TC Chelimsky Cleveland, OH, USA Poster #39 Cardiac vagal control in POTS I Bonyhay, J Chang, R Freeman Boston, MA, USA Poster #40 Neurohormonal and autonomic behaviour after head-up tilt in postural tachycardia syndrome (POTS) patients J Freitas, R Santos, F Boomsma, MJ Maciel Porto, Portugal Poster #41 Inflammatory cytokines are increased in postural tachycardia syndrome LE Okamoto, A Gamboa, BK Black, G Farley, SR Raj, D Robertson, I Biaggioni Nashville, TN, USA Poster #42 Postural orthostatic tachycardia syndrome and general anesthesia: a series of 24 cases JA Rabbitts, AK Jacob, PA Low, TB Curry Rochester, MN, USA Poster #43 Exercise training but not beta-adrenergic blockade treatment improves the reninaldosterone response during prolonged orthostasis in the postural orthostatic tachycardia syndrome Q Fu, TB VanGundy, S Shibata, DL Creson, BD Levine Dallas, TX, USA Pediatric Autonomic Disorders Chair: Gisela Chelimsky Poster #44 Postural tachycardia syndrome and functional gastrointestinal disorders: a role for Poster #30 Poster #45 Poster #46 Poster #47 Poster #48 Poster #49 Poster #50 altered electrical activity of the stomach? S Safder, T Chelimsky, B Braunstein, E Heller, M O’Riordan, G Chelimsky Cleveland, OH, USA The role of autonomic testing in elucidating symptom mechanism and guiding etiologic determination in a pediatric population D Sukul, G Chelimsky, A Alshekhlee, TC Chelimsky Cleveland, OH, USA Analysis of treatment outcomes in relation to autonomic testing results in a pediatric population D Sukul, TC Chelimsky, A Alshekhlee, G Chelimsky Cleveland, OH, USA The autonomic similarities between cyclic vomiting syndrome and migraine disorders S Madan, A Alshekhlee, E Heller, K McNeeley, TC Chelimsky, G Chelimsky Cleveland, OH, USA Sleep apnea induces deoxygenation in familial dysautonomia patients MJ Hilz, FB Axelrod, D Rapoport, I Ayappa, S Buechner, H Sczepanska, N Dimitrov, D Berlin, S Möller New York, NY, USA & Erlangen, Germany Non-psychiatric co-morbidities in pediatric functional gastrointestinal disorder: an area in need of exploration S Safder, E Heller, T Chelimsky, G Chelimsky Cleveland, OH, USA Pain can obscure autonomic dysfunction in acute, acquired small fiber neuropathy in children NL Kuntz, R Fealey Rochester, MN, USA POSTER SESSION III Saturday, November 1, 2008 7:00-8:30 AM Central and Peripheral Autonomic Disorders Chair: Peter Novak Poster #51 Loss of dopaminergic neurons in the ventral periaqueductal gray in autonomic synucleinopathies AM Schmeichel, GR Boone, P Sandroni, PA Low, JE Parisi, EE Benarroch Rochester, MN, USA Poster #52 Pupil reaction to olfactory stimuli in Parkinson’s patients and healthy controls C Schrezenmaier Schneider, T Ziemssen, J Lötsch, B Schuster, T Hummel Dresden, Germany Poster #53 Image analysis based detection of sweat in the thermoregulatory sweat test TE Prieto, WG Day, AC Barboi, SS Jaradeh Milwaukee, WI, USA Poster #54 Questionnaire based assessment of pelvic organ dysfunction in multiple system atrophy T Yamamoto, R Sakakibara, T Uchiyama, Z Liu, T Ito, Y Awa, T Yamanishi, T Hattori Chiba, Japan Poster #55 The diagnostic and therapeutic implication of cardiac MIBG scans in cases of clinically uncertain parkinsonian patients V Metta, B Corcoran, A Forbes, M Buxton-Thomas, KR Chaudhuri London, United Kingdom Poster #56 Time-frequency analysis of resting pupillary oscillations in small fiber neuropathy K Chémali, W Nowak, A HachoĊ, M Nakayama Cleveland, OH, USA Poster #57 Proximal leg fatigue as a manifestation of a neurogenic process with small fiber polyneuropathy predominance. Clinical, electrophysiological, autonomic testing and pathological data A Barboi, M Collins, S Jaradeh, T Prieto Milwaukee, WI, USA Poster #58 Coexistent autoimmune autonomic ganglionopathy and myasthenia gravis as a paraneoplastic syndrome in non-small cell lung cancer B Black, A Peltier, S Raj, K Smith, P Donofrio, D Robertson, I Biaggioni Nashville, TN, USA Poster #59 Parasympathetic heart rate reserve in autonomic failure patients J Tank, K Heusser, A Diedrich, FC Luft, J Jordan Hannover, Germany Poster #60 Association between orthostatic hypotension and supine hypertension in autonomic synucleinopathies MJ Tellez, LJ Norcliffe-Kaufmann, A Voustianiouk, S Lenina, H Kaufmann New York, NY, USA Poster #61 Supine hypertension is associated with elevated serum creatinine in patients with pure autonomic failure EM Garland, I Biaggioni, SR Raj, BK Black, D Robertson Nashville, TN, USA Poster #62 Spectral analysis of heart rate and blood pressure variability discriminates autonomic dysfunction associated with Parkinson’s disease and MSA-P S Duerr, J-P Ndayisaba, M Stampfer-Kountchev, R Granata, W Poewe, GK Wenning Innsbruck, Austria Poster #63 Treatment of multiple system atrophy using intravenous immunoglobulins – preliminary report P Novak, P Raven, BM White, A Williams, V Novak Worcester, MA, USA Poster #64 Autonomic dysfunction - who will provide the care? D Turner Collierville, TN, USA Autonomic Reflexes in Normotensive and Hypertensive States Chair: Chris Gibbons Poster #65 Role of the nucleus tractus solitarius in mediating cardiovascular and gastric responses evoked by auricular and body acupuncture stimulation SP Zhang, X Gao, B Zhu, Y Li Hong Kong, China Poster #66 Serotonin innervation of the nucleus tractus solitariius (NTS) augments sympathetic and ventilatory responses to hypoxia LH Kung, K Scrogin Maywood, IL, USA Poster #67 Cardiopulmonary reflexes influence on the circulation rapid regulation OV Mamontov, AN Kalinichenko, AO Conrady, EV Shlyakhto St. Petersburg, Russia Poster #68 A new noninvasive method to assess adrenergic baroreflex sensitivity W Singer, PA Low Rochester, MN, USA Poster #69 Paradoxical heart rate and muscle sympathetic activity modulation in a patient with isolated carotid baroreflex failure A Diedrich, K Sato, SR Raj, JL Netterville, I Biaggioni, D Robertson Nashville, TN, USA Poster #70 Neuroendocrinologic change in Creutzfeldt-Jakob disease H Kishida, S Koyano, Y Baba, Y Suzuki, Y Kuroiwa Yokohama, Japan Poster #71 Dysfunction of autonomic nervous system activity in schizophrenia Poster #72 Poster #73 Poster #74 Poster #75 Poster #76 Poster #77 Poster #78 Poster #79 Poster #80 I Kishida, M Fujibayashi, S Tanaka, C Ishii, N Ishii, T Kimura, T Moritani Kanagawa, Japan Diurnal variation of orthostatic blood pressure control after ischemic stroke L Desrochers, K Hu, M Selim, P Novak, L Lipsitz, P Zhao, V Novak Boston, MA, USA Hypertensive patients demonstrate low resting autonomic activity RR Arora, S Gosh Dastidar, J Colombo Chicago, IL, USA Age matched attenuation of autonomic activity in both branches in chronic hypertension RR Arora, S Gosh Dastidar, J Colombo Chicago, IL, USA Altered sympathetic and parasympathetic activity is associated in patients with chronic coronary artery disease RR Arora, S Gosh Dastidar, J Colombo Chicago, IL, USA Altered autonomic activity with atrial fibrillation as demonstrated by non-invasive autonomic monitoring S Nanavati, RJ Bulgarelli, J Vazquez-Tanus, S Gosh Dastidar, J Colombo, RR Arora Chicago, IL, USA Relationship between blood pressure, depression and anxiety. A step into the concept of psycobiotipo (mind-body relationship) LE Medina, J Ospina, MA Lemos, G Cuartas, D Aristizabal, J Calle, M Gutierrez, Y Torres Medellin, Colombia Medellin Heart Study. Study design and distribution by blood pressure, including hypotension LE Medina, D Aristizabal, J Gallo, J Ochoa, Y Torres, L Montoya, M Correa, R Restrepo, D Moreno, MP Correa, N Zapata, PA Gil, M Franco Medellin, Colombia Blood pressure characterization of essential hypotension and/or orthostatic hypotension LE Medina, W Uribe, J Marin, G Montero, B Astudillo, MA Restrepo, J Bernal, Y Torres, M Duque Medellin, Colombia Hemodynamics of fibromyalgia syndrome K Nagata, T Hasegawa Hamamatsu City, Japan This program is sponsored in part by unrestricted educational grants provided by the following. This support is gratefully acknowledged. Main Sponsor: Chelsea Therapeutics, Inc. Sponsors: Innovision, Inc. Award Sponsors: Finapres Medical Systems SDS/MSA Support Group