Unit 2: Genetic Processes Lesson 7: Incomplete Dominance and Codominance Complete Dominance: Complete Dominance: a situation where an allele will determine the phenotype, regardless of the presence of another allele. Ex: PP – purple Pp – purple pp – white Mendel’s work with what he called “typical plants” (homozygous dominant) and “atypical plants” (homozygous recessive) allowed him to see complete dominance and refute the idea of why traits of parents did not blend in the offspring. Yet, blended inheritance is common in nature. In snapdragons, one of the genes that that controls flower colour (C) has one allele for red flowers (CR) and another allele for white flowers (CW). The homozygous plant (CRCR) produces red pigment flowers, and the homozygous plant (CWCW) produces white pigment flowers; however, the heterozygous plant (CRCW) produces both the red and white pigment making pink flowers. The heterozygous phenotype is a blending of the two homozygous phenotypes and known as incomplete dominance. Incomplete Dominance: Incomplete Dominance: a situation where neither allele dominates the other and both have an influence on the individual; results in partial expression of both traits Codominance: Codominance: a situation where both alleles are expressed fully to produce offspring with a third phenotype. Ex: With shorthorn cattle, when a red bull is crossed with a white cow, it will produce a roan calf. Roan calves have intermingled pure white and pure red hair. ABO Blood Types – Codominance and Dominance: Human blood type is both a codominant and dominant genetic trait. There are four possible blood types and different alleles. If you have the allele IA, you will have the antigen A present on your red blood cells. If you have the allele IB, you will have the antigen B present on your red blood cells. If you have the allele i, you will have no antigens present on your red blood cells. If you have blood type blood type A, it means you have the antigen A on your red blood cells (erythrocytes) and you have the Anti-B antibodies in your blood plasma. The antibodies will produce an immune response against antigen B. Alternatively, blood type B will produce an immune response against blood types containing the A antigen. It is because of this reason, that you must be careful when doing blood transfusions. PHENOTYPE GENOTYPE Blood Group A Blood Group AB IAIA IAi IBIB IBi IAIB Blood Group O ii Blood Group B Which type is the universal donor? Which type is the universal recipient? ABLE TO RECEIVE BLOOD FROM: Type A or O ABLE TO GIVE BLOOD TO: Type A or AB Type B or O Type B or AB Type AB, A, B, or O Type AB Type O Type A, B, AB or O The I is used to represent immunoglobin which the protein on the surface of the RBC. Homework Questions: 1. Explain in your own words the meaning of dominance, codominance, and incomplete dominance. 2. In some chickens, the gene for feather colour is controlled by codominance. The allele for black is FB and the allele for white is Fw. The heterozygous phenotype is known as erminette. a) What is the genotype for black chickens? b) What is the genotype for white chickens? c) What is the genotype for erminette chickens? d) If two erminette chickens are crossed, what is the probability that they would have a black chick? A white chick? 3. A geneticist notes that crossing a round radish with a long radish produces oval radishes. When oval radishes were crossed with oval radishes, the F2 generation had these phenotypes: 100 long, 200 oval, and 100 round radishes. Use symbols to explain the results obtained for the F1 and F2 generations. 4. How would Mendel’s conclusions have differed if he had worked with plants whose alleles were incomplete dominant? 5. Thalassemia is an inherited anemic disorder in humans. Individuals can exhibit major anemia, minor anemia, or neither. Assume only one gene is involved with two alleles in the inheritance of this condition. What type of inheritance is thalassemia governed by? What are the corresponding gentoypes to the three scenarios? 6. List the possible genotypes for an individual with type A blood. 7. Suppose a father of blood type A and a mother of blood type B have a child of type O. What are the possible blood types of the mother and father? 8. Suppose a father of blood type B and a mother of blood type O have a child of type O. What are the chances that their next child will be blood type O? Type B? Type A? Type AB? 9. Why is blood type inheritance an example of both codominace and complete dominance? 10. Another characteristic of human blood is the presence of absence of a blood protein called the Rh factor. People with the protein are Rh+ and those without it are Rh-. Use the Internet and other resources to answer the following questions: a) What are the genotypes of individuals who are Rh- and Rh+? Is this an example of complete dominance, incomplete dominance, or codominace? b) How can the Rh blood type of two parents be of concern during a pregnancy?how can possible harmful complications be avoided? SOLUTIONS: