2013 第四届国际神经科技大会会议日程 Theme: A New Era in Cancer Research and Therapy Time: May 23-25, 2013 Venue: Hilton Xi'an, China Opening Ceremony & Keynote Forum Time: 09:40-12:10, May 23, 2013 (Thursday) Place: Yan Huang Hall, 2nd Floor, Hilton Xi'an Moderator Dr. Xiaoyan Jiang, Senior Scientist, Associate Professor, BC Cancer Research Centre, University of British Columbia, Canada 09:40-10:10 Title: Personalized Cancer Medicine: Conceptual, Organizational and Financial Challenges Dr. Alexander Maximiliaan Eggermont, Professor and Director, Institute Gustave Roussy, France 10:10-10:40 Title: Changing Landscape in Clinical Oncology Phase 1: Can We More Efficiently Translate Our Growing Biological Understanding of Cancer into Relevant Novel Treatments? Dr. Bruno Osterwalder, Senior Vice President, Senior Strategic Advisor Oncology, Merck Serono Darmstadt, Switzerland 10:40-11:10 Title: New Drugs Developed in China for NSCLC in Recent Years Dr. Yan Sun, Member of Chinese Academy of Engineering; Director, National GCP Center for Anticancer Agents, Cancer Hospital/Institute, CAMS &PUMC, China 11:10-11:40 Title: Cancer Targeting Gene-Viro-Therapy (CTGVT) Dr. Xin-Yuan Liu, Member of Chinese Academy of Sciences, Institute of Biochemistry and Cell Biology; Professor, College of Life Science, Zhejiang Sci-Tech University, China 11:40-12:10 Title: Viral Cancer Vaccines and Tumor Associated Antigens (TAA) in Immunotherapy, Preventive and Curative Dr. Giulio Tarro, President, Foundation De Beaumont Bonelli, Sbarro Health Research Organization, Adjunct Professor, Temple University, USA Chapter 1: Cancer Related Policy and Public Health Stream 101: Cancer Related Policy and Public Health Time: 13:30-16:15, May 23, 2013 (Thursday) Place: Xian Yang Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair Dr. Bo Hang, Staff Scientist, Life Sciences Division, Lawrence Berkeley National Laboratory, USA Dr. Jennifer E Gallagher, Reader in Oral Health Services Research; Honorary Consultant in Dental Public Health, King's College London Dental Institute At Guy's, St Thomas's and King's College Hospitals, UK 13:30-13:55 Title: A Targeted Approach to Raising Awareness of the Early Signs of Cancer Amongst, African, Asian, African Caribbean, Irish and Chinese Communities Living in England Dr. Paula Lloyd Knight, Associate Director, National Cancer Action Team, UK 13:55-14:20 Title: Thirdhand Smoke (THS) Causes DNA Damage in Human Cells Dr. Bo Hang, Staff Scientist, Life Sciences Division, Lawrence Berkeley National Laboratory, USA 14:20-14:45 Title: Maternal Passive Smoking during Pregnancy and Neonatal Health Dr. Artur Wdowiak, Head of Laboratory of Diagnostic Procedures, Medical University in Lublin, Poland 14:45-15:10 Title: Cancer: A Time Bomb for Indonesia Dr. Hasbullah Thabrany, Chairman, Center for Health Economics and Policy Studies, Universitas Indonesia, Indonesia 15:10-15:25 Coffee Break 15:25-15:50 Title: The Public Health Aspects of Tobacco Control Revisited Dr. Jennifer E Gallagher, Reader in Oral Health Services Research; Honorary Consultant in Dental Public Health, King's College London Dental InstituteAt Guy's, St Thomas's and King's College Hospitals, UK 15:50-16:15 Title: The Impact of Pesticide Exposure on Breast Cancer Incidence: Evidence from Costa Rica Dr. Carolina Santamaria-Ulloa, Professor, Universidad de Costa Rica, Costa Rica Chapter 2: Cancer Epidemiology and Prevention Stream 201: Cancer Genetics, Epidemiology, Biostatistics and Prevention Time: 13:30-17:05, May 23, 2013 (Thursday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair 13:30-13:55 Dr. Karan P. Singh, Professor, Department of Medicine, University of Alabama at Birmingham, USA Title: An Innovative Model for Predicting Outcome in Cancer Patients Dr. Karan P. Singh, Professor, Department of Medicine, University of Alabama at Birmingham, USA 13:55-14:20 Title: Association of CD44 Polymorphisms with Early Onset of Breast Cancer Dr. Juhua Zhou, Professor, Institute for Tumor Immunology, Ludong University School of Life Sciences, China 14:20-14:45 Title: Esophageal Adenocarcinomas: Do Phytoestrogens Play a Role? Dr. Yunxia Lu, Associate Professor, Karolinska Institute, Sweden 14:45-15:10 Title: An Aberrant Hypermethylated Gene in NPC Dr. Hsin-Pai Li, Assistant Professor, Chang Gung University, Taiwan 15:10-15:25 Coffee Break 15:25-15:50 Title: Cutaneous Adult T-Cell Leukemia/Lymphoma (ATLL) Dr. Masahiro Amano, Associate Professor, Department of Dermatology, University of Miyazaki, Japan 15:50-16:15 Title: Evolution of a Transmissible Cancer: The Genetics and Epigenetics of the Tasmanian Devil Facial Tumour Disease Dr. Beata Ujvari, Postdoctoral Fellow, Faculty of Veterinary Science, University of Sydney, Australia 16:15-16:40 Title: Increased Incidence of Merkel Cell Carcinoma among Younger Statin Users Dr. Helka Tuulia Sahi, Researcher, Department of Pathology, Department of Plastic and Reconstructive Surgery, Helsinki University, Finland 16:40-17:05 Title: A Human Tumor Genome Project: From Sequence to Structure, Function and Possibly Drug Targets Dr. Jun Chen, Director, Tianjin Lung Cancer Institute, Tianjin Medical University General Hospital, China Stream 202: Cancer Screening, Monitoring, and Counseling for High-Risk Populations Time:13:30-15:10, May 24, 2013 (Friday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair Dr. Gian Dorta, Professor, CHUV, University Hospital Lausanne, Switzerland Dr. Eleanor O’Sullivan, Chair of Mouth Head and Neck Cancer Awareness Ireland, University College Cork, Ireland 13:30-13:55 Title: The Use of a Blood Based Pre-cancer, Non-pathological Risk Factor to Improve Compliance, Early Stage Detection Yield and Reduce Mortality and Health Costs of Colorectal Cancer Dr. Dayan Goodenowe, President and CEO, Phenomenome Discoveries Inc., Canada 13:55-14:20 Title: A New Blood-based Test for Colorectal Cancer Screening Dr. Gian Dorta, Professor, CHUV, University Hospital Lausanne, Switzerland 14:20-14:45 Title: Risk Adapted Screening in Bladder Cancer with the Internet Based Assessment Tool RiskCheck Bladder Cancer Dr. Gerson Ludecke, Senior Staff Urologist and Medical-Oncologist, UKGM Giessen, University Clinic, Germany 14:45-15:10 Title: A Novel Cancer Screening Indices Based on Plasma Free Amino Acid Profiles Dr. Minoru Yamakado, Special Adviser, Center for Multiphasic Health Testing and Services, Mitsui Memorial Hospital, Japan 15:10-15:25 Coffee Break Stream 203: Tobacco and Cancers Time: 15:25-17:30, May 24, 2013 (Friday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair Dr. Yuan-Soon Ho, Professor, Chairman, Translational Cancer Research Center, Graduate Institute of Biomedical Technology, Taipei Medical University, Taiwan Co-Chair 15:25-15:50 Dr. Patrizia Russo, Senior Researcher, IRCCS "San RaffaelePisana", Italy Title: Tea Polyphenols against Smoking-induced Worse-effects in Human Diseases through Inhibition of 9-nicotinic Receptor Expression Dr. Yuan-Soon Ho, Professor, Chairman, Translational Cancer Research Center, Graduate Institute of Biomedical Technology, Taipei Medical University, Taiwan 15:50-16:15 Title: Nicotine Promotes Human Bronchial Epithelial Cells “HBEpC” Transformation Induced by Benzo[a]pyrene-7,8-diol-9,10-epoxide through a7-nicotinic Receptor Mediated Pathways Dr. Patrizia Russo, Senior Researcher, IRCCS "San RaffaelePisana", Italy 16:15-16:40 Title: Perspectives of Breast Cancer Etiology Dr. Hong-Hong Zhu, Assistant Professor, Western kentucky University, USA 16:40-17:05 Title: The Analysis of the Human Whole Saliva Proteome of Heavy Smokers for Potential Biomarkers for Tobacco Related Diseases Dr. Zubaidah Haji Abdul Rahim, Professor, Department of Oral Biology, Faculty of Dentistry, University of Malaya, Malaysia 17:05-17:30 Title: Tobacco and Lung Cancer Incidence among Males Dr. Padmavath Amma Jayalekshmi, Assistant Professor, Regional Cancer Center, India Chapter 3: Etiology of Cancer Stream 301: Cancer-related DNA Damage, Repair and Cell Cycle Time: 13:30-17:05, May 23, 2013 (Thursday) Place: Shen Mu Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair Dr. Xiao Xu, CEO, ACEA Biosciences Inc., USA Dr. Eileen McGowan, Senior Research Fellow, Translational Cancer Research, University of Technology Sydney, Australia 13:30-13:55 Title: New Approaches in Mechanistic Study of Cancer Metastasis Dr. Xiao Xu, CEO, ACEA Biosciences Inc., USA 13:55-14:20 Title: Cancers and the Concept of Cell Senescence Dr. Alvaro Macieira-Coelho, Director of Research, National Institute of Health and Medical Research (INSERM), France 14:20-14:45 Title: PET-guided High-dose IMRT with Self-respiratory Gating in the Treatment of Non-small Cell Lung Cancer Dr. Jidong Lian, Staff Radiation Oncologist, Credit Valley Hospital, Trillium Health Partners, Canada 14:45-15:10 Title: Evaluation of Cell Cycle Arrest in Estrogen Responsive Breast Cancer Cells Dr. Eileen McGowan, Senior Research Fellow, Translational Cancer Research, University of Technology Sydney, Australia 15:10-15:25 Coffee Break 15:25-15:50 Title: Coordinated Utilization of Glucose and Glutamine Is Critical for Cell Proliferation Dr. Nianli Sang, Associate Professor, Drexel University, USA 15:50-16:15 Title: Dicer, DNA Damage and Tumorigenesis Dr. Kaifu Tang, Professor, Chongqing Medical University, China 16:15-16:40 Title: Combretastatin Analogues and Their Metal Complexes: The Powerful Combination of DNA Targeting with Antimitotic Activity Dr. Bernhard Biersack, Visiting Professor of Chemistry, AbedaInamdar Senior College, University of Pune, India 16:40-17:05 Title: The Other Faces of the PIM-2 Oncogene - Cell Cycle Arrest, Activation of Apoptosis, and Involvement in the DNA Damage Response Dr. Jeremy Don, The Mina &Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Israel Stream 302: Oncogenes, Tumor Suppressors and Carcinogens Time: 13:30-17:30, May 24, 2013 (Friday) Place: Shen Mu Hall, 2nd Floor, Hilton Xi'an Chair Dr. Yanping Zhang, Professor, Department of Radiation Oncology and Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, USA Co-Chair 13:30-13:55 Dr. Gunnar Westin, Professor, Department of Surgical Sciences, Uppsala University, Sweden Title: The RP-Mdm2-p53 Pathway Links Nutrient Stress to Liver Lipid Metabolism, Obesity, and Cancer Dr. Yanping Zhang, Professor, Department of Radiation Oncology and Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, USA 13:55-14:20 Title: Hypermethylation of Tumor Suppressor Genes in Breast Cancer Dr. Yinhua Yu, Professor, Obstetrics and Gynecology Hospital of Fudan University, China 14:20-14:45 Title: Hypermethylated in Cancer 1 (HIC1), a Tumor Suppressor Gene Epigenetically Deregulated in Hyperparathyroid Tumors by Histone H3 Lysine Modification Dr. Gunnar Westin, Professor, Department of Surgical Sciences, Uppsala University, Sweden 14:45-15:10 Title: The Regulation of p53 Isoforms Dr. Geng Liu, Associate Professor, Soochow University, China 15:10-15:25 Coffee Break 15:25-15:50 Title: Two Single Nucleotide Polymorphisms in the Von Hippel-lindau (Vhl) Tumor Suppressor Gene in Taiwanese Population with or without Renal Cell Carcinoma Dr. Yen-Chein Lai, Assistant Professor, Chung Shan Medical University, Taiwan 15:50-16:15 Title: Tumor Suppressive Activity of Smad3 through Regulation of Mir-200 Members in Gastric Cancer Dr. Suntaek Hong, Associate Professor, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, South Korea 16:15-16:40 Title: FBXW7 Institutes the Very Last Failsafe Program Against Tumor Progression Right Prior to the Early Stages of Metastasis Dr. Ningning Li, Research Associate, University College London, UK 16:40-17:05 Title: Distinct Regulation of Tumor Suppressor Genes by the Transcription Factor E2F in Response to Growth Stimulation and Oncogenic Changes Dr. Kiyoshi Ohtani, Professor, Department of Bioscience, KwanseiGakuin University, Japan 17:05-17:30 Title: Role of CD44 in Antigen Presentation and Its Implication in Anti-tumor Immune Response Dr. Juhua Zhou, Distinguished Professor and (Taishan Scholar)Director, Institute for Tumor Immunology, Ludong University School of Life Sciences, China Stream 303: Tumor Angiogenesis Time: 08:30-09:45, May 25, 2013 (Saturday) Place: Shen Mu Hall, 2nd Floor, Hilton Xi'an Chair Dr. Emanuela Masini, Professor, Department of NEUROFARBA, Section of Pharmacology, University of Florence, School of Medicine, Italy 08:30-08:55 Title: Selective Inhibition of Carbonic Anhydrase Ix: Target Enzyme for Diagnosis and Therapy of Renal Carcinoma Dr. Emanuela Masini, Professor, Department of NEUROFARBA, Section of Pharmacology, University of Florence, School of Medicine, Italy 08:55-09:20 Title: The Anti-hepatocarcinogenic Effect of Mushroom Extract is Mediated by the Inhibition of VEGF-induced PI3K/AKT Signaling Pathway Dr. Peter Cheung, Professor, School of Life Sciences, The Chinese University of Hong Kong, China 09:20-09:45 Title: A T-cadherin: Role in Melanoma Growth, Angiogenesis and Stromal Cell Recruitment Dr. Kseniya Rubina, Faculty of Basic Medicine, M.V. Lomonosov Moscow State University, Russia Stream 304: Cancer/Tumor Metastasis, Adhesion, Migration, and Invasion Time: 13:30-16:15, May 25, 2013 (Saturday) Place: Shen Mu Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair Dr. Tao Liu, Group Leader, Children's Cancer Institute Australia for Medical Research, Australia Dr. Ronald Y Chin, Consultant Otolaryngologist, Head and Neck Surgeon, Lecturer, Nepean Hospital, The University of Sydney, Australia 13:30-13:55 Title: Multiple Steps of HLA-G in Ovarian Carcinoma Metastasis: alter NK Cytotoxicity and Induce MMP-15 Expression Dr. Wei Hua Yan, Professor, Medical Research Center, Taizhou Hospital of Zhejiang Provinve, China 13:55-14:20 Title: New Stochastic Models of Carcinogenesis for Human Cancer Involving Multiple Pathways Dr. Hong Zhou, Assistant Professor, Department of Mathematics and Statistics, Arkansas State University, USA 14:20-14:45 Title: The Histone Demethylase JMJD1A Promotes Neuroblasotma Cell Metastasis Through Modulating Gene Transcription Dr. Tao Liu, Group Leader, Children's Cancer Institute Australia for Medical Research(CCIA), Australia 14:45-15:10 Title: STAT3 is Involved in Esophageal Carcinogenesis through Regulation of Oct-1 Dr. Zhipeng Wang, Associate Professor, Fourth Military Medical University, China 15:10-15:25 Coffee Break 15:25-15:50 Title: MicroRNA-499-5p Promotes Cellular Invasion and Tumor Metastasis in Colorectal Cancer by Targeting FOXO4 Dr. Haifeng Jin, The Fourth Military Medical University, China 15:50-16:15 Title: Human Papillomavirus Genotyping in Ovarian Cancer Saudis Patients Dr. Mohamed M. Hafez, Associate Professor of Virology and Immunology, Department of Cancer Biology, National Cancer Institute, Egypt Chapter 4: Personalized Medicine and Translational Medicine Stream 401: Personalized Medicine and Translational Medicine Time: 13:30-17:05, May 23, 2013 (Thursday) Place: Yu Lin A Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair 13:30-13:55 Dr. Christian Ensinger, Professor, Institute of Pathology, Medical University of Innsbruck, Austria Dr. Lei L Chen, Retired Associate Professor of Medicine, MD Anderson Cancer Center, USA Title: Exploiting Antitumor Immunity to Overcome Relapse��Rational, Efficacy in Gastrointestinal Stromal Tumor Model, and Implications in Other Malignancies Dr. Lei L Chen, Retired Associate Professor of Medicine, MD Anderson Cancer Center, USA 13:55-14:20 Title: Changes in Pathological Investigations from Histopathology to Molecular Evaluations Concerning Personalized Medicine in Cancer Treatment Dr. Christian Ensinger, Professor, Institute of Pathology, Medical University of Innsbruck, Austria 14:20-14:45 Title: Biobank and Its Application in Translational Medicine Dr. Hengjun Gao, Professor and Director, Biobank Brank Branch, China Medical Biotech Association, National Engineering Research Center, China 14:45-15:10 Title: Advanced High-Content Tissue Cytometry as an Essential Tool in Personalized Medicine Dr. Rupert C. Ecker, Chief Scientific Officer, Tissue Gnostics GmbH, Austria 15:10-15:25 Coffee Break 15:25-15:50 Title : Patient-derived First Generation TumourXenograft Model: A Promising Tool for Rapid Guidance of Chemotherapeutic Responsiveness in Patients with Pancreatic Cancer Dr. Aiqun Xue, Senior Research Fellow, Royal North Shore Hospital, Australia 15:50-16:15 Title: Plasmatic Levels of Angiogenetic and Immunosupressive Factors TGF Beta1, VEGF and Antitumor Cellular Immunity in Patients with Breast and Colon Cancer Dr. Eva Zavadova, Clinical Immunologist, Department of Oncology, General Teaching Hospital and 1st Faculty of Medicine, Charles University, Prague, Czech Republic 16:15-16:40 Title: Phytochemicals and Drug Resistance in Pancreatic Cancer Chemotherapy Dr. Yan Li, Senior Lecturer, Auckland University of Technology, New Zealand 16:40-17:05 Title: Thioredoxin-Dependent Cancer Prevention and Inflammatory Diseases Dr. Junji Yodoi, Professor, Kyoto University, Japan Chapter 5: Medical Research on Solid Tumors Stream 501: Breast Cancer Time: 16:15-17:55, May 23, 2013 (Thursday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair Dr. Shi Wei, Assistant Professor, University of Alabama at Birmingham, Medical Director, Immunohistochemistry Laboratory, UAB Hospital, USA 16:15-16:40 Title: What We Know about Primary Metastatic Breast Cancer – Pathological Characteristics and Outcome over a 10-year Period Dr. Jana Barinoff, Gynecological Oncologist, Kliniken Essen-Mitte, Germany 16:40-17:05 Title: Breast Cancer with Isolated Bone Metastatic Potential: A Different Animal? Dr. Shi Wei, Assistant Professor, University of Alabama at Birmingham, Medical Director, Immunohistochemistry Laboratory, UAB Hospital, USA 17:05-17:30 Title: Incorporation of Cost-effective Agents for the Prevention of Cancer Treatmentinduced Toxicities Dr. Biswa Mohan Biswal, Professor, School of Medical Sciences, University Science Malaysia, Malaysia 17:30-17:55 Title: Polysaccharide Suppresses Progression of Cancers via Inhibition of Transforming Growth Factor-β1 Receptors (TGFRs)-mediated Signals and Epithelial-to-mesenchymal Transition Dr. Hsien-Yeh Hsu, Professor, Yang-Ming University, Taiwan Stream 502: Colorectal Cancer, Colon, Rectal and Anal Cancer Management Time: 13:30-17:05, May 23, 2013 (Thursday) Place: Yu Huan Hall, 1st Floor, Hilton Xi'an Chair 13:30-13:55 Dr. Amale Laouar, Assistant Professor, Robert Wood Johnson Medical School-UMDNJ, USA Title: 2B4 is a Major Marker of Gut Immune Cells Induced and Maintained by the Intestinal Microbial Flora: Impact of the Intestinal Microbial Flora on Gut Immune Cells Dr. Amale Laouar, Assistant Professor, Robert Wood Johnson Medical School-UMDNJ, USA 13:55-14:20 Title: New Frontiers in Colorectal Cancer Surgery: The Rise of the Laparoscopist Mr. Adnan Alam, Consultant Colorectal Surgeon, Addenbrooke's Hospital, UK 14:20-14:45 Title: Effects of Abdominal Surgery on Postoperative Trunk Flexion Strength in Patients with Colorectal Cancer Ms. Irena Paiuk, Physical Therapist, The Stanley Steyer School of Health Professions, Department of Physical Therapy, Tel Aviv University, Israel 14:45-15:10 Title: Surgery of Colorectal Cancer in the Small Town of Komotini Dr. Christos Sotirios Simoglou, Surgical Clinic, Sismanogleio General Hospital, Greece 15:10-15:25 Coffee Break 15:25-15:50 Title: Perineal Approach for Resection of Carcinoma of Lower Third Rectum with Perineal Continent Colostomy Dr. Shantikumar Dhondiram Chivate, Sr.Surgeon, JeevanJyot Hospital Thane, India 15:50-16:15 Title: Tumor Specific Suppressor Bax Δ2 Family in MSI Tumors Dr. Jialing Xiang, Associate Professor, Illinois Institute of Technology, USA 16:15-16:40 Title: Pathogen-driven Colorectal Cancers: Time for a Treatment Paradigm Change? Dr. Bauyrzhan Aituov, Junior Researcher, Nazarbayev University, Kazakhstan 16:40-17:05 Title: Discovery of Novel Microtubule Polymerization and Depolymerization Inhibitor with Potent Antiproliferative and Antitumor Activity Dr. Lijuan Chen, Professor and Vice Director of State Key Laboratory of Biotherapy, Sichuan University, China Stream 503: Head, Neck, Nasopharyngeal, Oral Cavity Time: 08:30-11:40, May 24, 2013 (Friday) Place: Yu Huan Hall, 1st Floor, Hilton Xi'an Chair Co-Chair Dr. James Kevin Fortson, Chief, ENT Associates of South Atlanta, USA Dr. Ming-Liang He, Associate Professor, Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, The Chinese University of Hong Kong, China 08:30-08:55 Title: Head and Neck Cancer Screening in National and High-risk Populations in Ireland Dr. Eleanor O’Sullivan, Clinical Lecturer, Chair of Mouth Head & Neck Cancer Awareness Ireland, Cork University Dental Hospital, Ireland 08:55-09:20 Title: Study of the Lengh of Hospital Stay for Free Flap Reconstruction of Oral and Pharyngeal Cancer in the Context of the New French Casemix-based Funding and Comparison between Two Periods Dr. Angelique Girod, Medical Doctor, Institut Curie Comprehensive Cancer Center, France 09:20-09:45 Title: Nutritional Therapy for Patients with Head and Neck Cancer Dr. Jens Buentzel, Chair, Palliative Care Unit, SuedharzKlinikumNordhausen, Germany 09:45-10:10 Title: Carcinoma Involving the Sphenoid Sinus Dr. James Kevin Fortson, Chief, ENT Associates of South Atlanta, USA 10:10-10:25 Coffee Break 10:25-10:50 Title: MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2 Dr. Ming-Liang He, Associate Professor, Stanley Ho Center for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China 10:50-11:15 Title: The Expression and Prognostic Significance of Hepatoma-derived Growth Factor in Oral Cancer Dr. Yu-Wei Lin, Attending Physician, Chi Mei Medical Center, Taiwan 11:15-11:40 Title: Rare Tumours: Retropharyngeal and Laryngeal Synovial Cell Sarcomas Dr. Ronald Y Chin, Consultant Otolaryngologist, Head and Neck Surgeon, Lecturer, Nepean Hospital, The University of Sydney, Australia Stream 504: Esophagus and Lung Cancer Time: 13:30-15:10, May 24, 2013 (Friday) Place: Wan Da Hall, 1st Floor, Hilton Xi'an Chair Dr. Giulio Tarro, President, Foundation De Beaumont Bonelli, Sbarro Health Research Organization, Adjunct Professor, Temple University, USA 13:30-13:55 Title: An Introduction to My Approach Concerning the Fusion of Western and Traditional Chinese Medicine in Clinical and Basic Research of Cancer Dr. Chen-Yu Lee, Chief of YuSheng Chinese Medicine Clinic; Honorary Chairman of the ROC Chinese and Western Medicine Neurology Foundation; Honorary Ph.D. Advisor, LiaoNing University of Traditional Chinese Medicine, Taiwan 13:55-14:20 Title: Human Corin and Tumor Liberated Protein (TLP) in NSCL Cancer: Homology or Different Isoforms in the Sequence at the Cell Surface Dr. Giulio Tarro, President, Foundation De Beaumont Bonelli, Sbarro Health Research Organization, Adjunct Professor, Temple University, USA 14:20-14:45 Title: The Relation between Lymoh Node Metastasis and Recurrent Sites in Esophageal Carcinoma after Surgery Dr. Jiancheng Li, Director, Department of Radiation Oncology, Fujian Provincial Cancer Hospital, China 14:45-15:10 Title: FulvestrantIncreasesGefitinib Sensitivity in Non-Small Cell Lung Cancer Cells by Upregulating Let-7c Expression Dr. Hua Shen, Department of Oncology, First Affiliated Hospital of Nanjing Medical University, China 15:10-15:25 Coffee Break Stream 505: Prostate Cancer Time: 15:25-17:30, May 24, 2013 (Friday) Place: Wan Da Hall, 1st Floor, Hilton Xi'an Chair 15:25-15:50 Dr. Patricia Tai, Professor, University Saskatchewan, Allan Blair Cancer Center, Canada Title: The Management of Prostate Cancer with Very High PSA (Prostatic Specific Antigen) Dr. Patricia Tai, Professor, University Saskatchewan, Allan Blair Cancer Center, Canada 15:50-16:15 Title: Racial Differences in the Receipt of Definitive Treatment for Clinically Localized Prostate Cancer Dr. Willie Underwood, Associate Professor, Roswell Park Cancer Institute, USA 16:15-16:40 Title: Contemporary Management of Castration Resistant Prostate Cancer (CRPC) Dr. Hüseyin Engin, Head of the Department of Internal Medicine and Medical Oncology, BülentEcevit University Cancer Center, Turkey 16:40-17:05 Title: Prostate Cancer: Long Term Results of Combined Modality Treatment with No Hormonal Use Dr. Ariel Lederman, Radiosurgery New York, USA 17:05-17:30 Title: Hit by Waves-living with Local Advanced or Localized Prostate Cancer Treated with Endocrine Therapy or under Active Surveillance Dr. Kenneth Asplund, Professor, University of Tromsö, Norway Stream 506: Ureter, Bladder, Genitourinary and Testis Cancers Time: 13:30-14:20, May 24, 2013 (Friday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair 13:30-13:55 Dr. Alastair Thomson, Consultant Clinical Oncologist, Royal Cornwall Hospital, UK Title: Developments in Radiotherapy for the Treatment of Bladder Cancer Dr. Alastair Thomson, Consultant Clinical Oncologist, Royal Cornwall Hospital, UK 13:55-14:20 Title: Urinary Thrombomodulin is Down Regulated in Schistosomiasis Associated Bladder Cancer Dr. Ayman Mohamed Metwally, Assistant Professor, College of Applied Medical Science, Misr University for Science and Technology, Egypt Stream 507: Kidney Cancer, Renal Cell Cancer and Adrenal Cancers Time: 14:20-15:35, May 24, 2013 (Friday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair Dr. Yili Yang, Staff Scientist, National Cancer Institute at Frederick, USA 14:20-14:45 Title: Renal Cell Carcinoma with Secondary Hemophagocytic Syndrome Dr. Tze-Wah Kao, Assistant Professor, National Taiwan University Hospital, Taiwan 14:45-15:10 Title: Allergen Removed Rhus Verniciflua Stokes Extract (aRVS) as a Potential Option for Treatment of Metastatic Renal Cell Carcinoma (mRCC) Dr. Sookyung Lee, Associate Professor, Kyung Hee University Hospital, Korea 15:10-15:35 Title: Exploring the Mechanisms of Wilms' Tumor Development in Animal Models Dr. Yili Yang, Staff Scientist, Cancer and Developmental Biology Laboratory, National Institutes of Health, USA Stream 508: Brain Cancer Time: 08:30-10:10, May 25, 2013 (Saturday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair 08:30-08:55 Dr. Michael Repacholi, Visiting Professor, University of Rome "La Sapienza", Italy Title: Does Mobile Phone Use Cause Head Cancers? Dr. Michael Repacholi, Visiting Professor, University of Rome "La Sapienza", Italy 08:55-09:20 Title: Cytoplasmic Expression of HspB11 Correlates with the Clinical Grade of Brain Tumors Dr. Ferenc Gallyas, Professor, University of Pecs Medical School, Hungary 09:20-09:45 Title: Proliposomes: A Promising Formulation Approach of Liposomes for the Treatment of Brain Tumour Dr. Abdelbary Elhissi, Head of Drug Delivery Division, Institute of Nanotechnology and Bioengineering, University of Central Lancashire, UK 09:45-10:10 Title: Isolated Intracranial Rosai-dorfman Disease Mimicking Meningioma in a Child: A Case Report and Review of the Literature Dr. Naman Basant Bagdi, Consultant Interventional Radiologist, India 10:10-10:25 Coffee Break Stream 509: Overian, Cervical, Vulva, Vagina, Uterine Malignancies and Endometrial Cancers Time: 10:25-12:05, May 25, 2013 (Saturday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair 10:25-10:50 Dr. Juergen Engel, President and CEO, AEternaZentaris Inc., Canada Title: A Role for Estrogen Receptor Beta in Endometrial Cancer? Dr. Philippa TK Saunders, Professor, MRC Centre for Reproductive Health, The University of Edinburgh, UK 10:50-11:15 Title: AEZS-108 / 125 – A New Targeting Approach for Breast and Gynaecological Cancers Dr. Juergen Engel, President and CEO, AEternaZentaris Inc., Canada 11:15-11:40 Title: The Use of Hemi-V-Y Fasciocutaneous Advancement Flaps for Reconstruction of the Vulva after Radical Surgery Dr. Max A. Clark, Associate Professor, Wright State University School of Medicine, USA 11:40-12:05 Title: The Primary Study Of Molecular Classification Of Human Endometrial Cancer Dr. JianLiu Wang, Professor and Vice Chairman,Department of Obstetrics and Gynecology, Peking University People's Hospital, China Chapter 6: Diagnosis and Prognosis of Cancers Stream 601: Diagnosis and Prognosis of Cancers Time: 13:30-17:55, May 23, 2013 (Thursday) Place: Zhao Jun Hall, 1st Floor, Hilton Xi'an Chair Co-Chair Dr. Beiyun Chen, Associate Professor, Department of Pathology and Laboratory, Mayo Clinic, USA Dr. Simona Gurzu, Associate Professor, Department of Pathology, University of Medicine and Pharmacy of TarguMures, Romania 13:30-13:55 Title: Depleted Blood Levels of GTA-446 as a Sensitive Biomarker of Colorectal Cancer Dr. Dayan Goodenowe, President and CEO, Phenomenome Discoveries Inc., Canada 13:55-14:20 Title: Circulating Tumor Cells in Breast Cancer Dr. Beiyun Chen, Associate Professor, Mayo Clinic, USA 14:20-14:45 Title: CTCs&CSCs: Does These Rare Events Keep All the Necessary Information about the Appearance of Metastasis and Pleomorphic of the Disease? Evidence and Facts after Multiple Form Analysis Dr. Ioannis Papasotiriou, Medical Director, R.G.C.C.-Research Genetic Cancer Centre Ltd, Greece 14:45-15:10 Title: Detection of a-Fetoprotein and Glypican-3 mRNAs in the Peripheral Blood of Hepatocellular Carcinoma Patients by Using Multiple FQ-RT-PCR Dr. Qingfang He, Associate Chief Technician, Zhejiang Provincial Center for Disease Prevention and Control, China 15:10-15:25 Coffee Break 15:25-15:50 Title: Diagnosis and Treatment of Multiple Myeloma and AL Amyloidosis with Focus on Improvement of Renal Lesion Dr. Kenshi Suzuki, Director of Department of Hematology, Japanese Red Cross Medical Center, Japan 15:50-16:15 Title: Febrile Complications after Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Intra-pulmonary Mass Lesions of Lung Cancer Dr. Kazuyoshi Imaizumi, Professor, Division of Respiratory Medicine and Clinical Allergy, Department of Internal Medicine, Fujita Health University, Japan 16:15-16:40 Title: Platform Evaluation in Isolation of Circulating Tumor Cells in Lung Cancer Patients Dr. Dimple Chudasama, Thoracic Research Associate, Royal Brompton & Harefield NHS Trust, UK 16:40-17:05 Title: Histogenesis of Kaposi Sarcoma - A Challenging Issue Dr. Simona Gurzu, Associate Professor, Department of Pathology, University of Medicine and Pharmacy of TarguMures, Romania 17:05-17:30 Title: Plasmablastic Lymphoma of Oral Cavity - Microscopic to Molecular Magnitude with Review of Cases Dr. Neeta Bagul, Professor, Dr. D. Y. Patil Dental College and Hospital, India 17:30-17:55 Title: Tio2 Nanomaterials for Biosensing Applications of Anticancer Drugs and Cancer Cells Dr. Jingjie Cui, Associate Professor, College of Life Information Science & Instrument Engineering, Hangzhou Dianzi University, China Chapter 7: Cancer Nursing and Integrative Medicine Stream 701: Oncology Nursing Time: 13:30-16:15, May 23, 2013 (Thursday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair Dr. Margaret I Fitch, Head of Oncology Nursing and Director, Odette Cancer Center, Sunnybrook Health Sciences Centre, Canada Co-Chair 13:30-13:55 Dr. Tamis C. Besse, University Hospital Nijmegen, The Netherlands Title: Medical Oncologist Attitudes and Practice in Cancer Pain Management: A National Survey Dr. Brenda Breuer, Epidemiologist, Department of Pain Medicine & Palliative Care, Beth Israel Medical Center, USA 13:55-14:20 Title: Self-care Self-efficacy Effects on Patients' Quality of Life Dr. Elise Lev, Professor, Rutgers University, USA 14:20-14:45 Title: The Dutch National Guideline: Diagnosis and Treatment in Patients with Pain and Cancer Dr. Tamis C. Besse, Anesthesiologist, FIPP, University Medical Centre Nijmegen, The Netherlands 14:45-15:10 Title: Creating a Survivorship Program Dr. Margaret I Fitch, Head of Oncology Nursing and Director, Odette Cancer Center, Sunnybrook Health Sciences Centre, Canada 15:10-15:25 Coffee Break 15:25-15:50 Title: Acute Oncology Service: Improving Patient Care and Outcome Dr. Charlotte Thomson, Locum Consultant in Medical Oncology, Weston General Hospital, UK 15:50-16:15 Title: The Nutritional Status in Patients Undergoing Pancreatoduodenectomy Dr. Maria G Serna-Thome, Medical Nutrition Department, National Institute of Cancerología Av San Fernando, Mexico Stream 702: Integrative Medicine and Interventional Methods in Oncology Time: 13:30-17:30, May 25, 2013 (Saturday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair Dr. Gerry Bodeker, Professor, Columbia University; Oxford University, UK Co-Chair Dr. Yves Jean Bignon, Professor and Director, Department of Oncogenetics, Jean Perrin Center, France 13:30-13:55 Title: Roles of Melatonin Suppression and Circadian Disruption due to Light Pollution in Cancer Causation Dr. Russel J. Reiter, Professor, University of Texas Health Science Center, USA 13:55-14:20 Title: « PACThe » Programme for Accompagnying Breast Cancer Patients after Completion of Chemotherapy : Results of a Randomized Trial on 251 Patients Dr. Yves Jean Bignon, Professor and Director, Jean Perrin Comprehensive Cancer Center, France 14:20-14:45 Title: The Traditional Chinese Medicine to Anticancer Dr. Tao Chen, Professor, The Medical College of Three Gorges University, China 14:45-15:10 Title: Use of RFA to Control Hepatic Metastases from Neuroendocrine Malignancy Dr. Florencia Que, Associate Professor of Surgery, Mayo Clinic, USA 15:10-15:25 Coffee Break 15:25-15:50 Title: Integrative Oncology Meets Immunotherapy: New Prospects for Combination Therapy Dr. Gerry Bodeker, Professor, Columbia University; Oxford University, UK 15:50-16:15 Title: Quercetin Exerts Anti-melanoma Action and Inhibits STAT3 Signaling Dr. Zhiling Yu, Associate Professor, Director, Research and Development Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China 16:15-16:40 Title: Cancer Rehabilitation at the Mayo Clinic Dr. Kenley D. Schmidt, Assistant Professor, Mayo Clinic, USA 16:40-17:05 Title: Postoperative Critical Care of the Surgical Oncology Patient: Advances and Special Considerations Dr. Mark Sawyer, Assistant Professor of Surgery, Mayo Clinic, USA 17:05-17:30 Title: Information Wave of P53 Could be Used for the Anti-cancer Therapy Dr. Won H. Kim, Professor, Department of Biochemistry, Wonju College of Medicine, Yonsei University, Korea Chapter 8: Cancer Biomarkers Stream 801: Genomic, Proteomic and Transcriptomic-based Biomarkers in Cancer Time: 08:30-12:55, May 24, 2013 (Friday) Place: Yu Lin A Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair 08:30-08:55 Dr. Jianhua Luo, Professor, University of Pittsburgh School of Medicine, USA Dr. Peter Selby, Professor, University of Leeds, UK Title: Clinical Proteomics in Renal Cancer Dr. Peter Selby, Professor, University of Leeds, UK 08:55-09:20 Title: Genome Biomarkers of Prostate Cancer Dr. Jianhua Luo, Professor and Director, University of Pittsburgh School of Medicine, USA 09:20-09:45 Title: Proteins Differentially Expressed in Ovarian Surface Epithelial Cells Carrying a BRCA1 Mutation are Potential Biomarkers for Ovarian Cancer Dr. Guoxiong (Bob) Xu, Scientist and Director, Jinshan Hospital, Fudan University, China 09:45-10:10 Title: Determination of a Biomarker for Cervix Cancer Using Proteomics on Cervicovaginal Fluid Dr. Xaveer Van Ostade, Professor, Laboratory of Proteinscience, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Belgium 10:10-10:25 Coffee Break 10:25-10:50 Title: Secretory miRNA as Novel Cancer Biomarkers Dr. Jian Zhang, Associate Professor, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, China 10:50-11:15 Title: Collection, Preserving and Transporting of Blood Biomarker Dr. Xian Wu, Product Specialist, Becton Dickinson Medical Devices (Shanghai) Co Ltd. , China 11:15-11:40 Title: Apolipoprotein Biomarkers for Pancreatic Cancer Dr. Aiqun Xue, Senior Research Fellow, Royal North Shore Hospital, Australia 11:40-12:05 Title: The Role and Significance of Endothelial Progenitor Cells During Progression, Metastasis, and Recurrence of Hepatocellular Carcinoma Dr. De-cai Yu, Hepatobiliary Surgery, Nanjing University, China 12:05-12:30 Title: PPARγ Mediates the Effects of WIN55,212-2, an Synthetic Cannabinoid, on the Proliferation and Apoptosis of the BEL-7402 Hepatocarcinoma Cells Dr. Qing Zhao, Professor, Department of Biochemistry,Guangzhou Medical University, China 12:30-12:55 Title: HLA and Cancer: From Geno-susceptibility to Clinical Use Dr. Liya Ju, Special Representative for International Collaboration, China Relation of Gustave Roussy, France Stream 802: Comprehensive Gustave Roussy Cancer Center: Structural, Clinical and Research Projects Time: 08:30-10:50, May 25, 2013 (Saturday) Place: Yu Lin A Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair Dr. Alexander Maximiliaan Eggermont, Professor and Director, Institute Gustave Roussy, France Dr. Liya Ju, Special Representative for International Collaboration, China Relation of Gustave Roussy, France 08:30-08:55 Title: Institut Gustave Roussy and Ongoing Projects Dr. Alexander Maximiliaan Eggermont, Professor and Director, Institute Gustave Roussy, France 08:55-09:20 Title: Collaboration in Cancer Field between IGR and Chinese Cancer Hospitals Dr. Liya Ju, Special Representative for International Collaboration, China Relation of Gustave Roussy, France 09:20-09:45 Title: NanoOxaza, Pre-activated Oxazaphosphorines Prodrugs Designed for Drug Delivery Strategy with Wide Anticancer Activity Dr. Angelo Paci, Head of the Pharmacology and Drug Analysis Department, Institut Gustave Roussy, France 09:45-10:10 Title: The Relapse Risk after Autologous Transplantation in Patients with Newly Diagnosed Myeloma is Not Dependant of the Tumor Cell Load among Infused Cells and the Outcome is Not Improved by CD34+Cell Selection: Long Term Follow-up of an EBMT Phase III Randomized Study Dr. Jean-Henri Bourhis, Institut Gustave Roussy, France 10:10-10:25 Coffee Break 10:25-10:50 Title: Insights in Retroperitoneal Sarcomas: New Technical Considerations in Surgery from E-Surge, a Master Class in Sarcoma Surgery, and Presentation of an Ongoing International Trial from EORTC–STBSG Dr. Sylvie Bonvalot, Head of Visceral Surgery, Institute Gustave Roussy, France Stream 803: Cancers Biomarkers Time: 08:30-11:50, May 25, 2013 (Saturday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair Dr. Erwin Schleicher, Professor, University of Tuebingen, Germany Dr. Gerson Ludecke, Senior Staff Urologist and Medical-Oncologist, Department of Urology, UKGM Giessen, University Clinic, Germany 08:30-08:55 Title: Abnormal DNA Content in Cancer Detection and Prognosis Dr. Bojana Turic, President and CEO, Perceptronix Medical Inc ., Canada 08:55-09:20 Title: Ocurrence and Relevance of Maillard Products in Cancer Dr. Erwin Schleicher, Professor, Department of Internal Medicinal, Section Clinical Chemistry, University of Tubingen, Germany 09:20-09:45 Title: Split-course, High-dose Palliative Pelvic Radiotherapy for Locally Progressive Hormone-refractory Prostate Cancer Dr. Nirdosh Kumar Gogna, Professor, Princess Alexandra Hospital-Mater Centre, Australia 09:45-10:10 Title: Comparison of Urine Markers (UBC-rapid, NMP22 BladderChek, BTA-stat) in its Specificity influenced by Blood Dr. Gerson Ludecke, Senior Staff Urologist and Medical-Oncologist, Department of Urology, UKGM Giessen, University Clinic, Germany 10:10-10:25 Coffee Break 10:25-10:50 Title: Cerebrospinal Fluid Interleukin-10 is a Potentially Useful Biomarker in Immunocompetent Primary Central Nervous System Lymphoma (PCNSL) Dr. Takashi Sasayama, Assistant Professor, Department of Neurosurgery, Kobe University, Japan 10:50-11:15 Title: RP215 and GHR106 Monoclonal Antibodies as Drug Candidates for Cancer Immunotherapy Dr. Gregory Lee, Professor Emeritus, UBC Center for Reproductive Health, University of British Columbia, Canada 11:15-11:50 Title: Cancer and Metastatic Lymph Nodes Obtained by Endobronchial Ultrasound-guided Transbronchial Needle Aspiration of Carotid Body Tumors Dr. Takashi Anayama, Assistant Professor, Kochi University, Japan Chapter 9: Innovative Technologies in Cancer Research Stream 901: Animal Models and Mathematical Models Time: 08:30-10:35, May 24, 2013 (Friday) Place: Xian Yang Hall, 2nd Floor, Hilton Xi'an Chair Dr. Janne Koch, Facility Manager, Department of Experimental Medicine, Faculty of Health sciences, University of Copenhagen, Denmark 08:30-08:55 Title: The Cellular Cancer Resistance of the SR/CR Mouse Dr. Janne Koch, Facility Manager, Department of Experimental Medicine, Faculty of Health sciences, University of Copenhagen, Denmark 08:55-09:20 Title: Quantitative Radiobiological Model for Evaluating Radiotherapy Plans for Prostate Cancer Treatment Dr. Pradip Deb, Senior Lecturer, School of Medical Sciences, RMIT University, Australia 09:20-09:45 Title: Effects of Oral Administration of Fucoidan Extracted from Cladosiphonokamuranus on Tumor Growth and Survival Time in a Tumor-Bearing Mouse Model Dr. Yoshiharu Okamoto, Professor, Tottori University, Japan 09:45-10:10 Title: Genome-wide Screening of Genes and Genetic Pathways involved in Mouse Pancreatic Cancer Metastasis Using an Orthotopic Mouse Model Ms. Fang Cao, Department of Pathology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, China 10:10-10:35 Title: Trans-PET® — A Powerful Tool in Cancer Research Mr. Lu Wan, Product Specialist, Riverine Technology, China Stream 902: Cancer Stem Cells Time: 10:35-12:40, May 24, 2013 (Friday) Place: Xian Yang Hall, 2nd Floor, Hilton Xi'an Chair Dr. LuZhe Sun, Professor and Dielmann Endowed Chair in Oncology, Department of Cellular & Structural Biology, University of Texas Health Science Center at San Antonio, USA Co-Chair 10:35-11:00 Dr. Tao Ye, Professor, Hong Kong Polytechnic University, China Title: Novel Histone Demethylase LSD1 Inhibitors Selectively Targets Cancer Cells with Pluripotent Stem Cell Properties Dr. Tao Ye, Professor, Hong Kong Polytechnic University, China 11:00-11:25 Title: Mammary Stem Cell and Tumorigenesis Dr. LuZhe Sun, Professor and Dielmann Endowed Chair in Oncology, Department of Cellular & Structural Biology, University of Texas Health Science Center at San Antonio, USA 11:25-11:50 Title: Cancer Stemness: Activation of Stemness Genes in Lung Cancer Dr. Cheng-Wen Wu, Distinguished Chair, Professor, National Yang-Ming University, Taiwan 11:50-12:15 Title: Microenvironment of Cancer Stem Cells Dr. Yan Zhang, Professor, School of Life Sciences, Sun Yat-sen University, China 12:15-12:40 Title: A Small-Molecule Library Targeting AML Stem Cells Dr. Yue Chen, Professor, College of Pharmacy the State Key Laboratory of Medicinal Chemical Biology, Nankai University, China Stream 903: Innovative Technologies in Cancer Research Time: 08:30-10:35, May 25, 2013 (Saturday) Place: Xian Yang Hall, 2nd Floor, Hilton Xi'an Chair Dr. Yufeng Li, Associate Professor, Division of Preventive Medicine, Comprehensive Cancer Center, University of Alabama at Birmingham, USA 08:30-08:55 Title: ROC Analysis Can Improve the Correlation between Histological Grade and Oncotype-Dx Recurrence Risk in Breast Cancer Dr. Yufeng Li, Associate Professor, Division of Preventive Medicine, Comprehensive Cancer Center, University of Alabama at Birmingham, USA 08:55-09:20 Title: The Expression of Tumor Metastasis Suppressor Gene KAI1 and Matrix Metalloproteinase 2 in Breast Cancer Tissues Dr. Tong Zhang, Professor, Department of Oncology, Xinxiang Central Hospital, China 09:20-09:45 Title: Integrative Microarray Strategy for Screening and Evaluation of Compounds Modulating Erbb Receptor Activity in Cancer Cells Dr. Vehary Sakanyan, Professor, Nantes University &ProtNeteomix, France 09:45-10:10 Title: Realgar (REA) Nanoparticles: Physico-chemical Properties and Anticancer Effects Dr. Peter Balaz, Professor, Institute of Geotechnics, Slovak Academy of Sciences, Slovakia 10:10-10:35 Title: Nanotechnology in Liver Cancer Dr. Manfred George Krukemeyer, Lecturer of Surgery, Department of Radio-Oncology, Paracelsus-Hospital, Germany Chapter 10: Progress in Cancer Treatment Stream 1001: Progress in Cancer Treatment Time: 08:30-12:30, May 24, 2013 (Friday) Place: Yu Lin B Hall, 2nd Floor, Hilton Xi'an Chair Dr. Wenge Liu, Associate Research Professor, Department of Bioengineering, Duke University, USA 08:30-08:55 Title: Radiation Therapy for the Treatment of Prostate Cancer – Use of Various Modalities for Prostate Boost Dr. Anil K. Sharma, Clinical Professor, University of California, USA 08:55-09:20 Title: High Dose Rate Brachytherapy Boost for the Treatment of Cancer of the Prostate Dr. AM Nisar Syed, Professor, University of California, USA 09:20-09:45 Title: Injectable Seeds for Brachytherapy of Solid Tumor Using a Self-assembly Polypeptide Dr. Wenge Liu, Associate Research Professor, Department of Bioengineering, Duke University, USA 09:45-10:10 Title: Management of Advanced Gastric Cancer in Japan, the Difference between Other Countries Dr. Yasushi Tsuji, Director, KKR Sapporo Medical Center Tonan Hospital, Japan 10:10-10:25 Coffee Break 10:25-10:50 Title: Optimization of Adeno-associated Virus Vector for Cancer Gene Therapy Dr. Chengwen Li, Assistant Professor, UNC at Chapel Hill, USA 10:50-11:15 Title: Usefulness of a Double Dose Contrast Enhanced Magnetic Resonance Imaging for a Deliniation of Gross Tumor Volume in Stereotactic Radiotherapy for Metastatic Brain Tumors Dr. Takeo Takahashi, Professor, Department of Radiation Oncology, Saitama Medical Center, Saitama Medical University, Japan 11:15-11:40 Title: Improving Minimally Invasive Treatment of Rectal Cancer Through Robotic Assistance Dr. E. Ortiz Oshiro, Staff surgeon – Professor, Hospital Clínico San Carlos – Universidad Complutense, Spain 11:40-12:05 Title: Carbohydrate- A New Target of Immunotherapy for Ovarian Cancer Dr.Chih-Long Chang, Assistant Professor, Institute of Biomedical Science, Mackay Medical College, Taiwan 12:05-12:30 Title: Transfacial Approach to Skull Base Tumors Dr. Nicolas Avalos, Professor, Chilean Air Force Hospital, Chile Chapter 11: Anticancer Drug Discovery Stream 1101: New Targets, New Technologies for Anticancer Therapeutics (Part I) Time: 08:30-12:30, May 24, 2013 (Friday) Place: Zhao Jun Hall, 1st Floor, Hilton Xi'an Chair 08:30-08:55 Dr. Douglas D. Fang, Senior Director, WuXiApptec (Shanghai) Co., Ltd., China Title: Targeting Tumor Metabolism by Inhibition of Glyoxalases Dr. Gerd Birkenmeier, Professor, Medical Faculty, University of Leipzig, Germany 08:55-09:20 Title: Identification of Cancer Stem Cells Provides Novel Tumor Models for Drug Discovery Dr. Douglas D. Fang, Senior Director, WuXiApptec (Shanghai) Co., Ltd., China 09:20-09:45 Title: The History and Current Status of Global Anticancer Drugs Discovery and Development Dr. Charles Liu, Senior Vice President, Pharmaron, Inc., China 09:45-10:10 Title: Novel Fluorescent Probes Reveal Subcellular Differences that Could Enhance Cancer-targeting Specificity and Sensitivity Dr. Ta-Chau Chang, Professor, Institute of Atomic and Molecular Sciences, Academia Sinica, Taiwan 10:10-10:25 Coffee Break 10:25-10:50 Title: Blocking Hypoxia-inducible Pathways Could Enhance the Efficacy of Therapies in Treating Hepatocellular Carcinoma Dr. Xue-Ying Sun, Professor, Harbin Medical University, China 10:50-11:15 Title: KIF14 as an Oncogene: A Target for Novel Therapeutics? Dr. Timothy W. Corson, Assistant Professor, Indiana University School of Medicine, USA 11:15-11:40 Title: Repression of Human Telomerase Reverse Transcriptase Using Artificial Zinc Finger Transcription Factors Dr. Won H. Kim, Professor, Department of Biochemistry, Wonju College of Medicine, Yonsei University, Korea 11:40-12:05 Title: Targeting HDL/Apolipoprotein A-II Nanoparticle for Theranostic Drug Delivery System for Pancreatic Cancer Dr. Sohel Julovi, Postdoctoral Research Associate, Cancer Surgery Group, Kolling Institute of Medical Research, Department of Surgery, Northern Clinical School, The University of Sydney, Australia 12:05-12:30 Title: The Introduction of HL-085-001: A Novel Potential Anti-Cancer Drug Dr. Hongqi Tian, College of Biotechnology, Tianjin University of Science and Technology, China Stream 1102: Cancer Targeting Gene-Viro-Therapy(CTGVT) Time: 13:30-17:55, May 24, 2013 (Friday) Place: Xian Yang Hall, 2nd Floor, Hilton Xi'an Chair Dr. Xin-Yuan Liu, Professor and Director, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Xin Yuan Institute of Medicine and Biotechnology, College of Life Science, Zhejiang Sci-Tech University, China 13:30-13:55 Title: The "Cancer Targeting Gene-Viro-Therapy" Strategy Dr. Xin-Yuan Liu, Professor and Director, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Xin Yuan Institute of Medicine and Biotechnology, College of Life Science, Zhejiang Sci-Tech University, China 13:55-14:20 Title: Cancer Target Therapy: From Cell Signaling to Clinical Practice Dr. Jiong Wu, Richard J. Roberts Institute of Biotechnology in China, China 14:20-14:45 Title: Gene-Viro-Therapy Targeting to Cancer Stem Cells Dr. Qijun Qian, Professor, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, China 14:45-15:10 Title: Targeting Leukemia Cells with Oncolytic Adenoviruses Expressing sCAR-ligands Dr. Gongchu Li, Associate Professor, Zhejiang Sci-Tech University, China 15:10-15:25 Coffee Break 15:25-15:50 Title: Potent Antitumor Activity of Oncolytic Adenovirus Expressing Beclin-1 Via Induction of Autophagic Cell Death in Leukemia Dr. Wenbin Qian, Professor, The First Affiliated Hospital, College of Medicine, Zhejiang University, China 15:50-16:10 Title: Targeting Cancer Therapy Based on Survivin Mutants and Recombinant Oncolytic Vaccinia Virus Vectors Dr. Hui Yan, Professor, Zhejiang Academy of Medical Sciences, China 16:10-16:35 Title: Antitumor Effect of an Oncolytic Adenovirus Delivering TSLC1 for Hepatocellular Carcinoma via Induction of Caspase Apoptotic Pathway and Inhibition of Wnt Signal Pathway Dr. Yigang Wang, Associate Professor, Xinyuan Institute of Medicine and Biotechnology, College of Life Science, Key Laboratory of Silkworm Bioreactor and Biological Medicine of Zhejiang province, Zhejiang Sci-Tech University, China 16:35-17:05 Title: Combined Therapy with Cytokine-induced Killer Cells and Oncolytic Adenovirus Expressing IL-12 Induce Enhanced Antitumor Activity Dr. Cheng Qian, Professor, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, China 17:05-17:30 Title: Possible Guideline for Managing Terminal Haemorrhage In Palliative Care Patients with Advanced Cancer Discharged Home at the End of Their Lives Dr. Edith Ubogagu, Specialist Registrar and Research Fellow in Palliative Medicine, Royal Marsden Hospital, UK 17:30-17:55 Title: Sensitivity of Cervical CarcinomaCells to Vesicular Stomatitis Virus- induced Oncolysis: Potential Role of Human Papilloma Virus Infection Dr. Jia-Hu Wang, Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Canada Stream 1103: New Targets, New Technologies for Anticancer Therapeutics (Part II) Time: 13:30-15:35, May 24, 2013 (Friday) Place: Zhao Jun Hall, 1st Floor, Hilton Xi'an Chair Dr. Xiaoyan Jiang, Senior Scientist, Associate Professor, BC Cancer Research Centre, University of British Columbia, Canada 13:30-13:55 Title: A Novel Approach to Target Treatment-Naïve Leukemic Stem Cells Dr. Xiaoyan Jiang, Senior Scientist and Associate Professor, British Colombia Cancer Agency and University of British Colombia, Canada 13:55-14:20 Title: The HECTD3 E3 Ubiquitin Ligase Suppresses Cisplatin-induced Apoptosis via Stabilizing MALT1 Dr. Ceshi Chen, Professor, Kunming Institute of Zoology, Chinese Academy of Science, China 14:20-14:45 Title: Targeting Sumo-specific Proteases Toward Discovery of New Anticancer Therapeutics Dr. Huchen Zhou, Professor, Shanghai Jiao Tong University, China 14:45-15:10 Title: Mitochondrial Targeting of Tocopheryl Succinate Enhances its Pro-apoptotic Efficacy: A New Paradigm of Efficient Anti-cancer Therapy Dr. Lanfeng Dong, Senior Research Fellow, Apoptosis Research Group, School of Medical Science, Griffith University, Australia 15:10-15:35 Title: Triptolide Functions as a Potent Angiogenesis Inhibitor Dr. Ming-Fang He, Associate Professor, NJUT Sino-America Institute of Translational Medicine, China Stream 1104: Targeting DNA Damage Response, DNA Repair, Mitosis and Apoptosis Time: 08:30-11:40, May 25, 2013 (Saturday) Place: Han Zhong Hall, 2nd Floor, Hilton Xi'an Chair 08:30-08:55 Dr. Bernd Kaina, Professor, Department of Toxicology, University Medical Center, Germany Title: A New AminothiolRadioprotector to Suppress Radiation DNA Damage and Cancer Dr. William Fahl, Professor, University of Wisconsin-Madison; Founder, Chairman and Chief Scientific Officer, ProCertusBioPharm, Inc., USA 08:55-09:20 Title: Reversal of Apoptosis in Cancer and Normal Cells – Possible Linked with Cancer Recurrent and Tumor Formation Dr. Ming Chiu Fung, Professor, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China 09:20-09:45 Title: Verticillin A Overcomes Apoptosis Resistance in Human Colon Carcinoma through DNA Methylation-Depend Dr. Fei-Yan Liu, Professor, Zhejiang University, China 09:45-10:10 Title: The O6-Alkylguanine Response in the Therapy of Glioma and Melanoma Dr. Bernd Kaina, Professor, Department of Toxicology, University Medical Center, Germany 10:10-10:25 Coffee Break 10:25-10:50 Title: Targeting Aurora Kinase in Cancer Therapy Dr. Quentin Qiang Liu, Professor and Director, Institute of Cancer Stem Cell, Dalian Medical University, China 10:50-11:15 Title: Role of PARP Inhibitors in the Regulation of Cell Death and Inflammatory Processes Dr. Bela Melegh, Professor, University of Pecs Medical School, Hungary 11:15-11:40 Title: Investigation of the Mechanisms of Synergy between Aurora Kinase A Inhibitor and Low Concentration Paclitaxel Dr. Yao Lin, Research Associate, Cancer Research UK Cambridge Institute, University of Cambridge, UK Stream 1105: Targeting Signaling Pathways and Signal Transduction Time: 13:30-15:10, May 25, 2013 (Saturday) Place: Yu Lin A Hall, 2nd Floor, Hilton Xi'an Chair Co-chair 13:30-13:55 Dr. Yi Charlie Chen, Professor, Natural Science Division, Alderson-Broaddus College, USA Dr. Shudong Zhu, Professor, Central South University, China Title: How to Select Indications for Targeted Therapies such as a MEK Inhibitor Based on Biological Understanding, Preclinical Models and Early Clinical Activity Signals for Rational Choices of Target Indications Dr. Bruno Osterwalder, Senior Vice President, Senior Strategic Advisor Oncology, Merck Serono Darmstadt, Switzerland 13:55-14:20 Title: Targeting HIF Signaling to Inhibit Tumor Angiogenesis by a Novel Bioactive Compound Chaetoglobosin K Dr. Yi Charlie Chen, Professor, Natural Science Division, Alderson-Broaddus College, USA 14:20-14:45 Title: PI3K Iinhibition Potentiates Bcl-2 Dependent Apoptosis in Renal Carcinoma Cells Dr. Shudong Zhu, Professor, Central South University, China 14:45-15:10 Title: Differential Protein Expression In Human Chronic MyelogenousLeukaemia Cell Line (K562) Following Exposure to 2-Methoxy-1,4-Naphthoquinone Isolated from Impatiens Balsamina Linn Dr. Anthony Ho Siong Hock, Senior Lecturer, School of Biosciences, Taylor’s University, UniversitiTunku Abdul Rahman, Malaysia 15:10-15:25 Coffee Break Stream 1106: Drug Design and Lead Optimization Time: 15:25-17:30, May 25, 2013 (Saturday) Place: Yu Lin A Hall, 2nd Floor, Hilton Xi'an Chair Dr. Jian-Hui Wu, Associate Professor, Departments of Oncology and Medicine, McGill University, Segal Cancer Centre-Lady Davis Institute, Sir Mortimer B.D.-Jewish General Hospital, Canada 15:25-15:50 Title: Development of Anticancer Agents Targeting Tumor-specific Mutant Proteins Dr. Jian-Hui Wu, Associate Professor, Departments of Oncology and Medicine, McGill University, Segal Cancer Centre-Lady Davis Institute, Sir Mortimer B.D.-Jewish General Hospital, Canada 15:50-16:10 Title: Design and Synthesis of Indolin-2-one Derivatives as Multi-Kinase Inhibitors Dr. Ji-Wang Chern, Professor, School of Pharmacy, National Taiwan University, Taiwan 16:15-16:40 Title: Development of Novel Anti-angiogenic Agents as HIF-1a (HSP90) Inhibitor Dr. Young-Ger Suh, Professor, College of Pharmacy, Seoul National University, Korea 16:40-17:05 Title: The Quest for Antimetastatic Agents: From Natural Chalcones to Anti-invasive Lead Candidates Dr. Bart I. Roman, Postdoctoral Researcher, Department of Sustainable Organic Chemistry and Technology, Ghent University, Belgium 17:05-17:30 Title: Curcuminoids as Inhibitors of Thioredoxin Reductase: A Receptor based Pharmacophore and QSAR Study Dr. Durg Vijay Singh, Assistant Professor, Central University of Bihar Patna, India Chapter 12: Basic Sciences of Oncology Stream 1201: Tumor System Biology Time: 08:30-10:10, May 24, 2013 (Friday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair Co-Chair 08:30-08:55 Dr. Johannes Haybaeck, Professor, Medical University of Graz, Austria Dr. Monique Cadrin, Professor, University of Quebec at Trois-Rivieres, Canada Title: The Thigh Junction Protein Claudin1 Plays a Critical Role in Invasiveness Potential of ShRNA K8/18 Knockdown Epithelial Cancer Cells Dr. Monique Cadrin, Professor, University of Quebec at Trois-Rivieres, Canada 08:55-09:20 Title: New Concepts on the Understanding of Endometrial Stromal Sarcoma Dr. Johannes Haybaeck, Professor, Medical University of Graz, Austria 09:20-09:45 Title: Constraints of the Cancer Genome Architecture on Somatic Cancer Evolution - A New Systems Biology Approach of Cancer Progression Dr. Albert Rubben, Professor, Department of Dermatology, University Hospital RWTH Aachen, Germany 09:45-10:10 Title: The Novel Human Endogenous Retrovirus-related Gene, psitpte22-HERV, is Silenced by DNA Methylation in Cancers Dr. Qiaoyi Liang, Post-doctoral Fellow, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, CUHK Shenzhen Research Institute, Hong Kong,China 10:10-10:25 Coffee Break Stream 1202: Cancers Regulations and Tumor Immunology Time: 10:25-12:30, May 24, 2013 (Friday) Place: Yan An Hall, 2nd Floor, Hilton Xi'an Chair Dr. Danny N. Dhanasekaran, Professor, Samuel Noble Foundation Endowed Chair in Cancer Research, Deputy Director, Peggy and Charles Stephenson Cancer Center, University of Oklahoma, USA Co-Chair 10:25-10:50 Dr. Yanhua Chen, Associate Professor, East Carolina University, USA Title: Oncogenic Signaling by LPA in Ovarian Cancer Growth and Progression Dr. Danny N. Dhanasekaran, Professor, Samuel Noble Foundation Endowed Chair in Cancer Research, Deputy Director, Peggy and Charles Stephenson Cancer Center, University of Oklahoma, USA 10:50-11:15 Title: Cell Metabolism Revealed Dr. Denise Chen, Asia-Pacific Application Scientist, Seahorse Bioscience, USA 11:15-11:40 Title: Immunotherapy of Skin Cancer Dr. Stephen B. Tucker, Clinical Professor, University of Texas Health Science Center, USA 11:40-12:05 Title: Inhibition of Human Lung Cancer Cell Migration and Invasion by Claudin-7 through ERK/ MAPK Signaling Pathway Dr. Yanhua Chen, Associate Professor, Brody School of Medicine at East Carolina University, USA 12:05-12:30 Title: The Effect of MGN-3 Arabinoxylan on Innate Imunity Cells Dr. Jan Sedlak, Director, Cancer Research Institute, Slovak Academy of Sciences, Slovakia Stream 1203: Tumor Microenvironment Time: 10:25-12:05, May 25, 2013 (Saturday) Place: Shen Mu Hall, 2nd Floor, Hilton Xi'an Chair Dr. Raymond Bergan, Professor, Director of Experimental Therapeutics, Robert H. Lurie Cancer Center of Northwestern University, USA 10:25-10:50 Title: Therapeutically Targeting the Tumor- Microenvironment Interaction Dr. Raymond Bergan, Professor, Director of Experimental Therapeutics, Robert H. Lurie Cancer Center of Northwestern University, USA 10:50-11:15 Title: The Role and Contribution of the Endothelium to Formation of the Premetastatic Niche and to Organ Specific Metastasis Dr. Yaw-Chyn Lim, Assistant Professor, National University of Singapore, Singapore 11:15-11:40 Title: Molecular Mechanisms Regulating Expression and Function of Cancer-associated Carbonic Anhydrase IX Dr. Jaromir Pastorek, President, Institute of Virology, Slovak Academy of Sciences, Slovakia 11:40-12:05 Title: DACH1 Blocks Prostate Cancer Cell Growth and Interleukin-6 Signaling Dr. Kongming Wu, Associate Professor, Thomas Jefferson University, USA Chapter 13: Medical Research on Hematology & Oncology and Endocrine System Tumors Stream 1301: Medical Research on Hematology & Oncology and Endocrine System Tumors Time: 13:30-17:05, May 24, 2013 (Friday) Place: Yu Lin A Hall, 2nd Floor, Hilton Xi'an Chair Dr. Rajesh C Shrotriya, CEO, Chairman of the Board & President, Spectrum Pharmaceuticals, USA 13:30-13:55 Title: Pralatrexate, a Next Generation Anti-folate, and its Use in the Treatment of Peripheral T-cell Lymphoma and other Potential Indications Dr. Rajesh C Shrotriya, CEO, Chairman of the Board & President, Spectrum Pharmaceuticals, USA 13:55-14:20 Title: Clinical Achievements of the EORTC Lymphoma Group and Aspects of Future Group Strategy Dr. Paul Meijnders, Radiation Oncologist and Associate Professor, University of Antwerp, Belgium 14:20-14:45 Title: Hypofractionated Radiotherapy for Glioblastoma: Strategy for Poor-risk Patients or Hope for the Future? Dr. Mohan Hingorani, Consultant Clinical Oncologist, Castle Hill Hospital, UK 14:45-15:10 Title: Long-term Survival of GlioblastomaMultiforme Patients Treated with Tumor-treating Fields Dr. Aaron M. Rulseh, Radiologist, Na Homolce Hospital, Czech Republic 15:10-15:25 Coffee Break 15:25-15:50 Title: Prognostic Value of Cytomegalovirus in Patients with Glioblastoma and Clinical Implications Dr. Giuseppe Stragliotto, Director of Medical Neurooncology Unit, Karolinska University Hospital, Sweden 15:50-16:15 Title: A Comprehensive Study of TP53 Mutations in Chronic Lymphocytic Leukemia: Analysis of 1,287 Diagnostic and 1,148 Follow-up CLL Samples Dr. Sona Pekova, Head of Laboratory for Molecular Diagnostics, Chambon Inc., Czech Republic 16:15-16:40 Title: Microenvironment and Drug Response in Acute Lymphoblastic Leukemia Dr. Constantinos Demonacos, Lecturer and Principal Investigator, The University of Manchester, UK 16:40-17:05 Title: A Case of Synchronous Lung Adenocarcinoma and Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-associated Lymphoid Tissue (MALT) Type Dr. Chi Young Jung, Associate Professor, School of Medicine, Keimyung University, South Korea