Table of Contents Preface to the Second Edition Preface to the First Edition 1. Functions and Components of a Computer System THE STRUCTURE OF A COMPUTER SYSTEM THE CENTRAL PROCESSING UNIT Control Unit Arithmetic and Logic Unit HOW THE CPU WORKS Inside the Control Unit: Bus Interface Inside the Control Unit: Decode Unit Inside the Arithmetic and Logic Unit: Registers PERFORMANCE RATING OF THE CPU COMPUTER ARCHITECTURE Reduced Instruction Set Computers Parallel Processing Symmetric Multiprocessors Massive Parallel Computers THE FASCINATING WORLD OF MICROPROCESSOR MANUFACTURING THE FUTURE OF MICROPROCESSORS CONCLUSION 2. The Memory Unit WHAT IS CPU MEMORY? A Word on Bits and Bytes The Significance of Word Length MEMORY VARIETY Random Access Memory Read-Only Memory Cache Memory Buffer Memory Virtual Memory WHAT IS MEMORY MADE OF? Semiconductor Memory Core Memory Read-Only Memory Flash Memory Memory of the Future CONCLUSION 3. Mass Storage Devices MAGNETIC DISK STORAGE DEVICES Storage by the Gigabytes Safeguard the Stored Information Optimizing the Hard Disk Performance File Defragmentation Random Access Memory Disk Floppy Disks OPTICAL DISKS Read-Only Optical Disks Write-Once Read-Many Disks Erasable Optical Disks MAGNETIC TAPE DRIVES Table Cartridges THE FUTURE OF MASS STORAGE TECHNOLOGY Perpendicular Recording CONCLUSION 4. Input/Output Devices KEYBOARD TERMINALS MODEMS AND ACOUSTIC COUPLERS Acoustic Couplers Modems ANALOG-TO-DIGITAL CONVERTERS SCREEN-POINTING DEVICES Mouse, Trackball, and Joystick IMAGE DISPLAY MONITORS Monochrome Display Monitors Refresh Rate Color Monitors Shadow Mask and Aperture Grille Video Image Resolution Formation of Video Image FLAT-PANEL DISPLAYS Liquid Crystal Display Technology Color Flat-Panel Display Gas Plasma Display PRINTERS Daisy Wheel Printers Dot-Matrix Printers Laser Printers Dye Sublimation Printers Inkjet Printers CONCLUSION 5. An All-Digital Nuclear Medicine Department COMMUNICATION NETWORKS Types of Local-Area Networks Network Transmission Media METHODS OF DATA TRANSMISSION LOCAL-AREA NETWORK TOPOLOGY Star Network Ring Network Bus Network Communication protocol The Internet Internet Resources Picture Archiving and Communication Systems Image Display Digital Image Storage System Image Compression Problems with State-of-Art PACS Computers and Health Hazards CONCLUSION 6. Computer Software TYPES OF COMPUTER SOFTWARE OPERATING SYSTEM Graphical User Interface PROGRAMMING SOFTWARE Low-Level Computer Programming Languages Machine language Assembly language High-Level Computer Programming Languages FORTRAN COBOL PL/1 Pascal Ada BASIC C C++ and OOP Java HTML, Javascript, and the Web Implementation of a High-Level Language CONCLUSION 7. Image Acquisition Methods METHODS OF DATA ACQUISITION Frame Mode Acquisition Size of Acquisition Matrix Byte Mode Versus Word Mode Acquisition Dynamic Frame Mode Acquisition Multiple Gated and List Mode Acquisition CONCLUSIONS 8. Qualitative Image Analysis CONVOLUTION METHODS OF IMAGE ENHANCEMENT Image-Smoothing Filters Edge-Enhancement Filters FOURIER METHODS OF IMAGE ENHANCEMENT Fundamentals of Fourier Analysis Fourier Image Filters POINT PROCESSING OPERATIONS Background Subtraction Interpolated Background Subtraction Grayscales for Video Image Display Color Translation Table True Color Display Color Presentation of Radionuclide Images FRAME PROCESSING OPERATIONS Geometric Operations CONCLUSION 9. Basic Quantitative Image Analysis CREATING REGIONS OF INTEREST CURVE GENERATION AND ANALYSIS The Moving Average Method The Weighed Moving Average Method Curve Smoothing by Analytical Methods Miscellaneous Curve Manipulation Techniques CONCLUSION 10. Nuclear Cardiology METHODS OF DATA ACQUISITION List Mode Acquisition Multiple-Gated Acquisition Temporal Resolution Artifacts from Arrhythmia Buffered Gated-Beat Acquisition Artifacts from Delayed Gating Quantitative Analysis of Multiple-Gated Blood Pool Images Temporal Smoothing Frame Normalizations QUANTITATIVE DATA ANALYSES Left Ventricular Regions of Interest The Time–Activity Curve Functional Images Phase Analysis Presentation of Phase Analysis Results Amplitude Analysis FIRST-PASS CARDIAC STUDIES Data Acquisition Technique METHODS OF DATA REFORMATTING FOR FIRST-PASS STUDIES Reformatting of ECG-Gated List Mode Data Reformatting of Non-Electrocardiographically Gated List Mode Data Reformatting of Rapid Dynamic Frames Ventricular Function Evaluations Detection of Intracardiac Shunts CONCLUSION 11. Emission Computed Tomography SPECT INSTRUMENTATION: A SYSTEM DESCRIPTION The Computer System MATHEMATICS OF TRANSVERSE IMAGE RECONSTRUCTION The Simple Backprojection Method Filtered Backprojection Method What Is That Window Doing on the Ramp? Iterative Reconstruction Algorithms PHYSICAL FACTORS AFFECTING THE QUALITY OF SPECT IMAGES Linear Sampling Criteria Angular Sampling Criteria Photon Attenuation Correction Compton-Scattered Photons Noncircular Detection Motion Image Noise QUALITY ASSURANCE OF THE SPECT SYSTEM Camera Field Uniformity Center of Rotation Pixel Size Gated SPECT Three-Dimensional Image Reconstruction Multimodality Image Fusion CONCLUSION Appendices APPENDIX A: DIGITAL NUMBER SYSTEMS APPENDIX B: HOW ANALOG-TO-DIGITAL CONVERSION WORKS APPENDIX C: FOURIER TRANSFORM References