Nor-Cal EMS Policy & Procedure Manual BLS PROTOCOLS MODULE 1003 – EMT Optional Scope Drug Formulary INTRODUCTION TO DRUG FORMULARY 1. Communications Failure: In the event that a field provider is unable to establish or maintain voice contact and reasonably determines that a delay in treatment may jeopardize patient outcome, the provider may initiate any of the medications for which they have been trained and approved to use by Nor-Cal EMS. The only exception to this is when there is a Base Hospital Physician Order (BHPO) required. Medications/procedures requiring a BHPO shall not be performed during communications failure. Refer to the Communications Failure policy, in Miscellaneous Policies Module. 2. Drug Allergy (hypersensitivity): If the patient has a known allergy to any medication listed in this formulary, it is considered a contraindication for administration. 3. Scope of Practice: Only those providers which are accredited as an “EMT-OS” on duty for a provider with an EMT-OS provider agreement shall utilize the medications and skills listed in this policy. EPINEPHRINE Indications: Allergic reactions, anaphylaxis, asthma. Adult dose: Epinephrine 1:1000, 0.3 mg May repeat every five (5) minutes twice for a total of three (3) doses. Pediatric dose: Based on patient weight: as follows: a. If patient weight is less than 15 kg, consult base hospital physician for medication dosage. b. If patient weight is between 15 and 30 kg, give epinephrine 1:2000, 0.15 mg IM via auto-injector. i. May repeat every five (5) minutes twice 2 for a total of three (3) doses. ii. If patient has received a self-administered dose, may repeat once for a total of three (3) doses. c. If patient weight is greater than 30 kg give epinephrine 1:1000, 0.3 mg IM via auto-injector. i. May repeat every five (5) minutes twice 2 for a total of three (3) doses. ii. If patient has received a self-administered dose, may repeat once for a total of three (3) doses. Route of Administration: IM via auto-injector Trade Name: Adrenalin Classification: Endogenous catecholamine, sympathomimetic Actions: Epinephrine contains both alpha and beta adrenergic properties. It is because of these properties, epinephrine will increase heart rate, increase peripheral vascular resistance (PVR), increase blood pressure, and automaticity of the heart. It is a positive chronotropic and inotropic medication, as well as a potent bronchodilator. Contraindications: Tachyarrhythmias. No contraindications if the patient is in cardiac arrest or anaphylactic shock. Relative Contraindications: Severe hypertension, known coronary artery disease, patients greater than 50 years of age. Side Effects: Palpitations, anxiousness, headache, tachyarrhythmias, hypertension, and vomiting. Special Considerations: Epinephrine is slightly light sensitive, keep out of direct sunlight. Originated: January 1, 2006 Last Revision: August 28, 2012 Page: 1 of 3 BLS PROTOCOLS MODULE EMT Optional Scope Drug Formulary #1003 NALOXONE Indications: Known or suspected narcotic-induced respiratory depression or apnea. Dosage: Adult dose: 2 mg IM or IN. May repeat as needed for a maximum dose of 6 mg. NOTE: If no response after 6 mg has been administered, narcotic-induced toxicity should be questioned. Pediatric dose: 0.1 mg/kg IM or IN, maximum dose 2 mg. May repeat once. Consult Base Hospital Physician for order and dosage recommendation for infants less than 8 kg. Route of Administration: IM or Intra-nasal, (IN) Generic Name: Naloxone HCL Classification: Narcotic (opiate) antagonist Actions: Specific antidote for narcotic agents. Contraindications: Hypersensitivity and/or allergy. Do not give patient naloxone after the King Airway device has been inserted. Side Effects: May precipitate acute opiod withdrawal syndrome; may cause cardiac arrhythmias, vomiting, hypertension and severe agitation. Special Considerations: Consult base hospital before using with patients who take opioid medication routinely. Naloxone may have a shorter half-life than the narcotic and the patient may need repeat dosing. Large doses may be required to reverse the effects of Darvon and Darvocet. Patient may become combative, prepare to restrain as needed. PRALIDOXIME CHLORIDE: Indications: Nerve Agent Exposure and exposures to organophosphate compounds that produce signs and symptoms, of the pneumonic “SLUDGEM.” Dosage: One auto-injector, may repeat as needed up to a maximum of three (3) injections. Pediatric dosage: 50mg/kg/dose, maximum dose 2000 mg. Route of Administration: IM via Auto-injector Trade Name: 2-Pam CL, Protopam Chloride, Duodote Classification: oxime Actions: Reactivates cholinesterase that has been inactivated by a Nerve Agent/Organophosphate. Contraindications: Treatment is NOT TO BE GIVEN PROPHYLACTICALLY. Special Considerations: 1. Auto-injectors may be used on EMS personnel if they become exposed and have signs and symptoms of nerve agent exposure. 2. It is important that the auto-injectors are given into a large muscle area, preferable anterior thigh. 3. Accidental injections into the hand WILL NOT deliver an effective dose of the antidote. Originated: January 1, 2006 Last Revision: August 28, 2012 Page: 2 of 3 BLS PROTOCOLS MODULE EMT Optional Scope Drug Formulary #1003 ATROPINE: Indications: Nerve Agent Exposure and exposures to organophosphate compounds that produce signs and symptoms of the pneumonic “SLUDGEM.”. Dosage: May repeat atropine to dry pulmonary secretions to decrease respiratory distress. Pediatric dose: 0.05 mg/kg/dose, maximum dose 2 mg. Route of Administration: IM via auto-injector Trade Name: Duodote, prepackaged kit Classification: Parasympatholytic, anticholinergic Actions: In organophosphate poisoning, atropine competes for post synaptic receptors at neuromuscular and neuroglandular junctions which block the action of the poison. Contraindications: None when used for life-threatening emergencies. Relative contraindications: Hypertension, tachycardia. Side Effects: Pupil dilation, dry mouth, blurred vision, tachycardia arrhythmias. Toxic Effects: May produce an anticholinergic toxicity in extreme dosages. The pneumonic for anticholinergic toxicity is: Hot - as a Hare; Blind - as a bat; Dry - as a bone; Red - as a beet; Mad – as a hatter. Originated: January 1, 2006 Last Revision: August 28, 2012 Page: 3 of 3