cv_nes_3-2013

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CURRICULUM VITAE
NABIL EL-SHERIF, M.D.
Personal:
Address:
160 East 65th Street, Apt.26C, New York, N.Y. 10021
Martial Status:
Citizenship:
Tel/Fax:
E-mail:
Married, four children
U.S.A
(718) 630-3740, (718) 270-4106
nelsherif@aol.com
EDUCATION:
Faculty of Medicine, Cairo University, Cairo, Egypt, 1953-1959
M.B., B.Ch., December 1959
POST GRADUATE DEGREES:
Diploma of Internal Medicine, Cairo University, 1962
Diploma of Cardiovascular Diseases, Cairo University, 1963
Doctor of Medicine Thesis: "Comparative Study of Orthogonal and
Scalar Electrocardiology", Cairo University, 1965
Doctor of Medicine Degree in Internal Medicine, Subspecialty:
Cardiovascular Diseases, Cairo University, 1965
CERTIFICATION:
Diplomate of the American Board of Internal Medicine, 1975.
Diplomate of the American Board of Cardiovascular Disease, 1975
Diplomate of the American Board of Clinical Cardiac Electrophysiology, 1995
(Recertified 2005)
HOSPITAL and UNIVERSITY AFFILIATIONS:
Visiting Professor
Chief, Cardiology Division
Associate Vice Chairman
for Research
Director of Electrophysiology Program
Chief, Cardiology Division
Attending Physician
Professor
University of Chicago, EP Program
1990-January 1991
Veterans Administration Medical Center
October, 1978 - present
SUNY, Health Science Center at
Brooklyn, March 1986 - 2005
SUNY Health Science Center at
Brooklyn, March 1986- 2005
SUNY, Downstate Medical Center
Feb. 1984 - March 1986
Kings County Hospital, 1984- present
Department of Medicine, SUNY, Downstate
Medical Center, October 1978 - present
2
Professor
Associate Professor
Associate Professor
Assistant Professor
Director, Coronary Care Unit
Research Associate
Fellow in Cardiology
Assistant Professor
Lecturer in Cardiology
Staff Cardiologist and
Assistant Director of
Hemodynamic Laboratory
Clinical Demonstrator
Visiting Registrar
Resident
Intern
Department of Physiology, Graduate
School, SUNY, Downstate Medical Center
1983 - present
Department of Physiology, Graduate
School, SUNY Downstate Medical Center,
1979 - 1983
Department of Medicine, University of
Miami School of Medicine, June 1976 October 1978
Department of Medicine, University of
Miami School of Medicine, July 1974 May 1976
Veterans Administration Hospital, Miami,
Florida July 1974 - October 1978
Department of Cardiology, Mount Sinai
Medical Center, Miami Beach, Florida,
July 1973 - June 1974
Department of Cardiology, Mount Sinai
Medical Center, Miami Beach, Florida,
July 1972 - June 1973.
Cardiology Department, Faculty of
Medicine, Cairo University, 1972 - 1974
Cardiology Department , Faculty of
Medicine, Cairo University, 1967 - 1972
Cardiology Department , Cairo
University Hospital 1963 - 1972.
Cardiology Department , Faculty of
Medicine, Cairo University, 1963 - 1967
Cardiology Department , Hammersmith
Hospital, London, 1963 - 1964
Department of Medicine, Cairo University
Hospital, 1961 - 1963
Cairo University Hospital, 1960 - 1961
SOCIETY MEMBERSHIP:
American Association for the Advancement of Science
American College of Cardiology
American College of Chest Physician
American College of Physicians
American Federation for Clinical Research
American Heart Association
American Physiological Society
Cardiac Electrophysiology Society
Council on Basic Science, American Heart Association
National Association of VA Cardiologists
National Association of VA Physicians
National Electrophysiology Group
New York Academy of Science
New York Heart Association Electrophysiology Group
North American Society of Pacing and Electrophysiology
Sigma Xi Society, SUNY/HSC at Brooklyn Chapter
Albanian Society of Cardiology, Honary Member
3
OTHER ASSIGNMENTS:
Editorial Board,
1) Journal, American College of Cardiology, 1983 - 1987;
2) Journal of Electrophysiology, 1987-1989.
3) American Journal of Non-Invasive Cardiology 1989-present.
4) Journal of Cardiovascular Electrophysiology,1990-present.
5) PACE, 1990-present
6) New Trends in Arrhythmias , 1991-present
7) Journal of Cardiovascular Pharmacology and Therapeutics, 1995-present
8) Journal of Interventional Cardiac Electrophysiology, 1996-present
9) The Egyptian Heart Journal, 1998-present
10) Mediterranean Journal of Pacing and Electrophysiology (Co-Editor) 1998-present
11) The Open Pacing, Electrophysiology & Therapy Journal, 2008-present
12) Heart Rhythm Journal, 2008-present
Consultant, National Heart, Lung and Blood Institutes, 1974 - 1976
Reviewer,
American Journal of Cardiology, American Heart Journal, Circulation, Circulation Research, Chest,
European Journal of Cardiology, Pace, Science, American Journal of Physiology, etc..
Director,
Annual Electrocardiography Course, Greater Miami Heart Association, 1974 - 1978.
Director,
Course on "Cardiac arrhythmias in acute myocardial infarction",
American Heart Association, Miami Beach, 1977
Cardiovascular Program Specialist,
VA Central Office, Research Program 1981 - 1984
Acting ACOS/Research and Development,
BVAMC, Brooklyn, N.Y.,1984-1986.
Chairman, Research and Development Committee,
1994
VAMC, Brooklyn, N.Y., 1980-1982, 1984 - 1988, 1991-
Director, International Symposium on High Resolution EKG, Late Potentials and Noninvasive
Electrophysiology”, Nice, France, June 1990: June 1992; June 1994, June 1996.
Co-Director: International Symposium on “Management of Cardiac Arrhythmias”. Lille, France, Nov.
1995.
Co-Director: International Symposium on “Atrial Flutter and Fibrillation. From Basics to Clinical Application”.
Heidelberg, Germany, Oct. 1996
Director: International Symposium on “Recent Advances in Diagnosis and Management of Cardiac
Arrhythmias”.
Cairo , Egypt, Feb. 1997.
Co-Director: International Cardiovascular Symposium Beijing, P.B. China, Oct, 1998.
Director: International Symposium on Signal Averaged EKD and Late Potentials, CardioStim , 1990, 1992, 1994,
1996, 1998, Nice, France.
Director: International Symposium on Signal Averaged EKD and Late Potentials, and Noninvasive
Electrophysiology, Cardiostim, 2000, 2002, 2004, Nice, France
4
Ph.D. Thesis Completed in the Cardiovascular Research Laboratory
1. Robert H. Zeiler: “The Electrophysiologic and Contractile Responses of Canine Atrial Tissue to
Adrenocorticotropin: Adrenergic and Cholinergic Systems: (Ph.D. in Physiology, 1981).
2. Mark Restivo: “A Model of Reentrant Ventricular Activation” (Ph.D. in Biomedical Engineering, 1987).
3. Raphael Henkin: “The Signal Averaged Electrocardiogram: Spectrotemporal Mapping” (Ph.D. in
Biomedical Engineering, 1990).
4. Maha Hegazy: “Experimental Models of Atrial Flutter” (Ph.D. in Physiology, 1995).
5. Edward Benjamin Caref: “Computer-Based Techniques for Cardiac Mapping and Electrogram Analysis “
(Ph.D. in Biomedical Engineering, 1996).
6. Boyu Huang: “Alterations in Sarcolemmal Ion Channel Expression in Post Infarction Remodeled Heart”
(Ph.D. Physiology, 1998).
7. Gamal Abdallah Ali: “Risk Stratification of Sudden Death Following Myocardial Infarction” (Ph.D.
Physiology, Canal Suez University, 1998) ..
8. Magda Helal Mohammed: “Risk Stratification of Patients for serious arrhythmic events after myocardial
infarction by combinatorial non-invasive algorithm.” (PhD, Physiology, Alexandria University,1999)
9. Lili Deng: “ Post-Infarction signal transduction pathways as targets for novel therapeutic interventions”,
PhD in Molecular biology, 2004, SUNY Downstate Medical Center.
PREVIOUS AND CURRENT TRAINEES IN THE CARDIOVASCULAR RESEARCH LABORATORY OF DR. N. EL-SHERIF
Funding Source
Current Position
Name
Period
Training
William B, Gough, PhD
Rahul Mehra, PhD
Robert Zeiler, PhD
Mohamed Boutjdir, PhD
Mark Restivo, PhD
Hua Yang, PhD
Bulant Zaim, MD
Mashid Assadi, MD
Raphael Henkin, PhD
Wolfgang Schoels, MD
1979-81
1980-84
1981-85
1987-89
1982-87
1988-90
1988-91
1988-91
1986-92
1990-92
Post-doc
Post-doc
Doc thesis*
Post-doc
Doc thesis*
Post-doc
Post-doc
Post-doc
Doc thesis*
Post-doc
Dayi Qin, PhD
Nidal Isber, MD
Alberico Sorgato, MD
Ghazwan Butrous, MD
Gjin Ndrepepa, MD
Alaa Abdelmeguid, MD
Zhi Hao Zhang, PhD
Shu Zhang, MD
Maha Hegazy, MD, PhD
Edward Ben Caref, PhD
Bekir Cebeci, MD
Masaomi Chinushi, MD
Boyu Huang, PhD
Gamal Al-Attar, MD
1990-92
1992-94
1993
1994-95
1994-95
1993-95
1993-95
1995-96
1994-96
1992-97
1996-97
1996-98
1995-98
1996-98
Post-doc
Post-doc
Post-doc
Post-doc
Post-doc
Post-doc
Post-doc
Post-doc
Doc thesis*
Doc thesis*
Post-doc
Post-doc
Doc thesis*
Doc thesis*
NIH, Merit
NIH, Merit
NIH, Merit
NIH, Merit
NIH, Merit
NIH
NIH
NIH
NIH
Deutsche Herz
Gesellschaft
NIH
NIH
Italian Gov’t grant
NIH, Merit
Fulbright Grant
Merit
Merit
Proctor & Gamble
Egyptian gov’t.
NIH, Merit
Turkish gov’t
Medtronic Intn’l
SUNY HSC@B
Egyptian gov’t
Director, Applied Commun. Parsippany, NJ
Senior Scientist, Medtronic, Minneapolis, MN
Senior Scientist, Ayerst Wyeth, NJ
Cardiovascular Physiologist, BVAMC
Research Scientist, BVAMC
Biomed Eng, Henry Ford Hospital, Detroit, MI
Cardiac Electrophysiologist, Washington DC
Cardiology Consultant, Roosevelt Hospital, NY
Director, R&D, DelMar Avionics, Irvine, CA
Director, EP Program, Univ. of Heidelburg,
Germany
Assist’ Prof of Physiology, SUNY, Bklyn, NY
Assist’ Prof of Medicine, Columbia Univ. NY
Asst. Prof., Brescia, Italy
Director, Clin. Res., Pfizer, England
Cardiologist, Univ of Tirana, Albania
Attending Card, Henry Ford Hos, Detroit, MI
Res. Scientist, Wyeth-Ayerst Princeton, NJ
Director of EP, Univ. of Beijing, China
Asst. Prof Physiol, Alexandria Univ, Egypt
Asst Res Prof, SUNYHSC
Electrophysiology, Gulhama Academy, Turkey
Asst. Prof., Niigata, Japan
Research Assoc., BVAMC
Asst. Prof, Suez Canal Univ., Egypt
5
Magda Helal Mohamad
Madhavi Gidh-Jain, PhD
Keiji Yamamoto, PhD
Ai Hongbin, M.D.
1997-1999 Doc thesis*
1995-97 Post-doc
1999-2000 Post-doc
1999-2000 R.Scientist
Egyptian gov’t
Merit
Takeda Ind grant
China schlrshpCouncl
Asst. Prof, Assiut University, Egypt
Research Scientist, Wyeth-Ayerst, NJ
Research Scientist-Takeda Chem Ind, Japan
Professor,Biology Dept,Shandong Univ.PRC
* indicates PhD thesis completed in Dr. El-Sherif’s research laboratories; does not include CCEP trainees
Hala El-Adawi,
PhD
Steven Smith,
PhD
Tamara Baynham,
PhD
Anthony
tramontano, MD
Vikram
Lakireddy, MD
Gil Bub, PhD
Denny Himel,
PhD
Praja Lakireddy,
MD
Sajin Pilai, MD
20002002
20002002
20022003
20022004
20032005
20042007
20072011
20112013
2013-
Post-doc
Research
associate
Research
associate
Researc associate
Research Fellow
Cardipovascular
Physiologist
Cardiovascular
Phyiologist
Clinical/Research
fellow
Clinical/Research
fellow
VACOREAP
VACOREAP
VACOREAP
VACOREAP
SUNY/DS
Center for Molecular
Biology,Alexandia,Egypt
Research Associate-SUNY
Downstae Medical Center
Guidant Corp, Minneapolis, Mn
Cardiology fellow, SUNY/DS
2004-2006
VACOREAP
Vaco REAP,
MERIT
VA funds
VA funds
MAJOR RESEARCH FUNDING SUPPORT:
A. Federal Grants:
1.
Research Associate, NIH-HLBI Contract 72-2972-M (1973-1974) Total funds $50,000.00
2.
NIH-HLBI RO1HL 18139, 1975-1980 - "Mechanism of ischemic rhythm disorders." (Co-investigatorPrincipal investigator: Benjamin J. Scherlag, Ph.D.) Total Funds $350,100.00
3.
VA Cooperative Study - "Aspirin Therapy and Unstable Angina", 1976-1978, (Principal Investigator)
Total Funds $76,956.00
4.
VA Merit Grant - "Conduction Disorder in Myocardial Infarction", (Principal Investigator) 1976-1979.
Total Funds $70,400.00
5.
VA Merit Grant - "Antiarrhythmic and Autonomic drugs in ischemic reentrant rhythms", 1979-1982,
(Principal Investigator) Total funds $136,000.00
6.
VA Merit Grant - "Electrophysiology and Pharmacology of Ischemia- Related Ventricular Rhythms",
1982-1986, (Principal Investigator) Total Funds $373,000.00
7.
VA Merit Grant - "Study of Diastolic Activity on the Body Surface in Ischemic heart Disease", 19821985, (Principal Investigator) Total funds $86,000.00
8.
VA Merit Grant - "Electrograms of the Sinus Node and other Cardiac Pacemakers", 1982-1985, (Coprincipal Investigator) Total Funds $90,000.00
6
9.
NIH-HLBI-RO1 HL31341: "A low noise electrocardiogram in ventricular arrhythmias." December 1983 November 1986. (Principal Investigator) Total Funds $177,641.
10.
VA Merit Grant "Electrophysiology of Triggered Rhythms Post-Infarction in canine Heart" 1985-1988
(Co-Principal Investigator) Total Funds $188,000.
11.
VA Merit Grant "Effects of Amphiphiles on the Contractility of Cultured Cardiac Myocytes" 1986-1989
(Co-Principal Investigator) Total Funds $88,000.
12.
VA Merit Grant "Correlation of Activation and Refractory Patterns of Reentrant Excitation" 1986-1991
(Principal Investigator) Total Funds $600,000.
13.
NIH-HLB1-RO1 HL 36680: Activation Patterns of Reentrant Rhythms. July 1986-June 1991 (Principal
Investigator) Total Funds $608,223.
14.
NIH-HLB1-HC-85-20: "Cardiac Arrhythmia Treatment Study" - Clinical Center. August 14, 1986 December 31, 1992. (Principal Investigator) Total Funds $1,112,000.
15.
NIH-HLBI-R01 HL 31341: "A low noise electrocardiogram in ventricular arrhythmias." (Renewal)
December 1986-November 1989 (Principal Investigator) Total Funds $270,000.
16.
NIH-HLBI-HC-91-:
"Multicenter Unsustained Tachycardia Trial" (MUSTT)
(Pricipal Investigator, participating Center) Total funds $317,000.
17.
VA Merit grant: "Electrophysiology of circus movement atrial flutter."
(Principal Investigator). Total funds $610,000.
18.
VA Merit Grant: "A model of propagation and electrical activity in reentrant circuits". April 1991 - March
1994. (Co-Principal Investigator)
Total funds $450,000.
19.
VACO-Cooperative Study: " Warfarin and aspirin in secondary prevention." August 1992-June 1998,
(Principal Investigator, partcipating center). Total funds $310,000.
20.
VA Merit Grant: "Adrenergic regulation of cardiac calcium channels". April 1994 - March 1997 (CoPrincipal Investigator) Total funds $275,800.
21.
American Heart Association: Grant-in-Aid: “IgG from mothers whose children have congenital heart
block inhibit voltage-gated cardiac calcium channels” 1996-1999 (Co-PI) Total funds $120,000.
22.
NIH-HLB1-R0156650: “Cellular mechanisms of auto immune associated congenital heart block” 19962000 (Co-PI): Total funds $840,000.
23.
VA Merit Grant: “Optical Mapping of early afterdepolarization in the long QT Syndrome” 1996-1998.
(Co-PI): Total funds $300,000.
24.
VA Merit Grant: Molecular and electrophysiological basis of post-infarction remodeling” 1996-2003.
Principal Investigator. Total funds $450,000.
25.
VACO-Cooperative study #399: “The affects of anti-arrhythmic therapy on maintaining stability of sinus
rhythm in atrial fibrillation” (Principarl Investigator, participating center) 1998-2003, Total funds
$150,000.
10/1/1991 - 9/30/1996
Oct. 1991 - Sept. 1996
7
26.
VACO-REAP: “Cardiac Remodeling and Arrhythmogenesis” Principal Investigator 2000-2005$3,417,000.
27.
NIH-HLBI-RO1-074869. Calcium Kinetics& Arhythmias in hypertrophy+Ischemia. Principal
Investigator, 2004-2009. Total direct funds :1,250,000. Pending
28.
NIH-Centers of Excellence-Resource-Related Research Grants, R24. PI-Research Core.
2004-2007. Total direct funds: $ 825,000
29.
VA MERIT grant: “Altered Calcium kinetics and arrhythmogenesis in ischemia/reperfusion”. Principal
Investigator. 2004-2009. Total funds $800,000.
B.
Non-Federal Grants:
1.
"Lopressor Intervention Trial." Ciba-Geigy, 1979-1982, (Principal Investigator) Total Funds $151,400.00
2.
"Comparison Between Tined Porous and Tined Standard Endocardial pacing Leads." 1979-1981,
(Principal Investigator) Pacesetter, Total Funds $11,000.00
3.
"Value of Endocardial Electrograms in Early Detection of Pacemaker Failure." 1981-1982, Medtronics,
Inc. Total Funds $5,000.00
4.
"Cardiovascular effects of Amoxapine." 1982-1983, (Principal Investigator) American Cyanamid
Company, Total Funds $25,000.00
5.
"Labetalol and Hydrochlorothiazide Trial in Moderate to Moderately Severe Essential Hypertension."
1982-1983, (Principal Investigator) Schering Corp. Total Funds $56,000.00
6.
"Labetalol vs Prazosin: Comparative Hemodynamics of Blood Pressure and Pulse at Rest and Exercise."
1983-1984, (Principal Investigator) Schering Corp. Total Funds $64,000.00
7.
"Indecainide (LY135837) in patients with ventricular arrhythmias." 1983-1986, (Principal Investigator)
Lily Research Laboratories. Total Funds $350,000.
8.
"Double-blind placebo-controlled multi-center trial of Ibopamine in patients with congestive heart
failure." 1985-1988 (Principal Investigator) Smith, Kline and French Laboratories. Total Funds $99,000.
9.
"The safety and effifacy of SCH33844 versus Coptril in mild to moderate essential hypertension." 19851987 (Principal Investigator) Schering Corp. Total Funds $85,000.
10.
"Vasotec (Enalapril Maleate) in patients with uncomplicated mild to moderate essential hypertension."
1986-1987 (Principal Investigator) Merk, Sharpe and Dohme, Total Funds $25,000.
11.
"Prognostic value of rhythms in heart rate and blood pressure in patients with coronary artery disease."
1987-1989, (Co-Principal Investigator). American Health Assistance Foundation, Total Funds $45,000.
12.
"The safety and efficacy of labetalol versus Metyldopa in mild to moderate essential hypertension in
blacks." 1988-1990 (Principal Investigator) Schering Corp. Total Funds $69,000.
13.
"Circadian anti-ischemia program." 1988-1989 (Principal Investigator) Pfizer Inc., Total Funds $20,000.
8
14.
"A multi-center dose range study comparing the efficacy and safety of ethmozine, encainide and placebo
using a double blind parallel randomized design." 1988-1992 (Principal Investigator) Dupont Nemours &
Co.,Inc. Total Funds $109,289.
15.
"Eight week double-blind comparison of amlodipine, diltiazem, and placebo."Oct. 1990 -Sept. 19
(Principal Investigator).National Medical Research Corporation.Total funds $16,000.
16.
"Prospective randomized controlled study of the efficacy of oral milrinone vs. placebo in congestive heart
failure." Mar. 1989 - Sept. 1991 (Principal Investigator). Sterling Winthrop Research Institute. Total
funds $58,284.
17.
"Cholesterol and recurrent events (CARE) study." 1990 - 1996. (Participating center PI). Brigham and
Womens Hospital. Total funds $120,000.
18.
"A randomized, open label, dose response study of BM 06.22 (r-PA) relative to Alteplase on coronary
artery patency and safety in patients with myocardial infarction."
1991 - 1992. Boehringer Mannheim
Pharm. Total funds $108,000.
19.
"Double blind parallel study comparing the antianginal activity of three doses of modified transdermal
nitroglycerin and placebo in patients with coronary artery disease". 1992-1993, Schering Plough Research.
Total funds $83,000.
20.
"Electrophysiologic effects of NE-10064" 1994-1995. Procter & Gamble Pharmaceuticals. Total funds
$375,000.
21.
“An open label dose range finding study of multiple oral doses of NE-10064 to determine safety and
antiarrhythmic efficacy” 1994-1995. Proctor & Gamble Pharmaceuticals. Total funds $275,000.
22.
“T-wave alternans. A multicenter study”., 1996-2000. Cambridge heart Inc. Total funds $75,000.
23.
“Mode Selection trial in sinus mode dysfunction-(MOST)”: Multicenter study. Mount Sinai Medical
Center 1997-2000, Total funds $50,000.
24.
“Sudden Cardiac Death in Heart Failure (SCD-HfT)”: NIH, 1997-2000, Total funds $100,000.
Honors:
*Magistral Lecture: Reentrant Arrhythmias: Basic mechanisms and clinical considerations. The 10th
International Symposium on Pogress in Clinical Pacing. Rome, December 3-6, 2002.
*Outstanding Achievement Award: The European Cardiac Arhythmia Society (ECAS). Marseille,
France, June 3-5, 2007.
* 2010 Pioneer of Cardiac Pacing and Electrophysiology, Heart Rhythm society, Denver, 2010
9
N. EL-SHERIF, M.D.
PUBLISHED ORIGINAL REFEREED ARTICLES:
1.
El-Ramly, Z.M., El-Sherif, A., El-Sherif, N., Sallam, F. and Sorour,A.H. Comparative study of the ECG
patterns in chronic core pulmonale.Bull. Egypt. Soc. Cardiol. 5:37-52, 1965.
2.
El-Sherif, N., El-Ramly, Z.M., Sorour, A.H. Sallam, F.A. The orthogonal electrocardiogram Bull. Egypt
Soc. Cardiol 6:63-80, 1966.
3.
Sorour, AH., El-Sherif, N., El-Ramly, Z.M. and Sallam, F.A. The corrected orthogonal electrocardiogram
in normal subjects (Frank lead system). Bull. Egypt. Soc. Cardiol 6:81-102, 1966.
4.
El-Sherif, N., El-Ramly, Z.M. El-Mallah, S., Sorour A.H. Total anomalous pulmonary venous drainage
into the left innominate vein. J. Egypt. Med. Assn. 51:275-289, 1968.
5.
El-Sherif, N., El-Ramly, Z.M., Sorour, A.H. Idiopathic dilatation of the pulmonary artery. J. Egypt. Med.
Assn. 51:509-527, 1968.
6.
El-Sherif, N., El-Ramly, Z.M., Sorour, A.H. Primary pulmonary hypertension. J. Egypt. Med Assn.
51614-637, 1968.
7.
El-Sherif, N., El-Mallah, S., El-Ramly, Z.M., Sorour, A.H. The acquired Lutembacher's syndrome, a cause
for "silent mitral stenosis". J. Egypt. Med. Assn. 51:723-736, 1968.
8.
El-Sherif, N., Atrial parasystole in a case of A-V block. Bull. Egypt. Soc. Cardiol. 8:47-51, 1968.
9.
El-Sherif, N. Silent myocardial infarction in mirror image dextrocardia. J. Egypt. Med. Assn. 52:692-695,
1969.
10.
El-Sherif, N., Saad, Y., El-Ramly, Z.M., Sorour, A.H. Unusual features in constrictive pericarditis "the
effect of uneven constriction". J. Egypt. Med. Assn. 52:903-921, 1969.
11.
El-Sherif, N., El-Ramly, Z.M., Sorour, A.H. Oesophageal electrocardiography in the study of cardiac
arrhythmias. Brit. Heart J. 31:414-425, 1969.
12.
El-Sherif, N. Supraventricular tachycardia with A-V block Brit. Heart J. 32:46-56, 1970.
13.
El-Sherif, N., Shahwan, L., Sorour, A.H. The effect of acute thermal stress on general and pulmonary
hemodynamics in the cardiac patient. Amer. Heart J 79:305-313, 1970.
14.
El-Sherif, N. The RSR pattern in left surface leads in ventricular aneurysm. Brit. Heart J. 32:440-448,
1970.
15.
El-Sherif, N. Rheumatic tricuspid stenosis. A hemodynamic correlation. Brit. Heart J. 33:16-31, 1971.
16.
El-Sherif, N. A-V junctional versus left atrial rhythm. Brit. Heart J. 633:358-366, 1971.
17.
El-Sherif, N. Intraventricular trifascicular block. Observations on the conduction disturbance in the
bundle branch system. Brit. Heart J. 33:626-628, 1971.
18.
El-Sherif, N. Tachycardia-dependent versus bradycardia-dependent intermittent bundle branch block.
Brit. Heart J. 34:167-176, 1972.
10
19.
El-Sherif, El-Ramly, Z.M. External left atrial pulse tracing in extreme left atrial dilation. Amer. Heart J.
84:387-394, 1972.
20.
El-Sherif, N. Paroxysmal atrial flutter and fibrillation. Induction by carotid sinus compression and
prevention by atropine. Brit. Heart J. 37:1024-1028, 1972.
21.
El-Sherif, N. A suggested mechanism for Mobitz type II block based on concealed atrial reciprocation.
J. Electrocardiography 5 (4) 401-406, 1972.
22.
El-Sherif, N. Intermittent trifascicular block. Different mechanisms of conduction disturbances in bundle
branches. Amer. J. Cardiol. 31:71-77, 1973.
23.
El-Sherif, N., Saad, Y., El-Ramly, Z.M. Evaluation de la conduction ventriculoauriculaire dans un
rhythme ventriculaire induit au hasard. Acta Cardiologia 28:379-391, 1973.
24.
El-Sherif, N., Mascarenhas, G., Zaron, S., Samet, P. Ventricular parasystolic rhythm masquerading as
bilateral bundle branch block. J. Electrocardiography 6 (2):171-174, 1973.
25.
El-Sherif, N. Observations on atrio-sinus conduction: Single, repetitive and complete atrio-sinus block,
atrio-sinus concealed and Wenckebach conduction. J. Electrocardiol. 6(2):113-124, 1973.
26.
Lazzara, R., El-Sherif, N., Scherlag, B.J. Electrophysiological properties of canine Purkinje cells in oneday-old myocardial infarction. Circ. Res. 33:722-734, 1973.
27.
El-Sherif, N. Tachycardia and bradycardia-dependent bundle branch block after acute myocardial
ischemia. Brit. Heart J. 36:291-301, 1974.
28.
El-Sherif, N., Scherlag, B.J., Lazzara, R., Samet, P. The pathophysiology of tachycardia and bradycardiadependent block in the canine proximal His-Purkinje system following acute myocardial ischemia. Amer.
J. Cardiol. 33:529-540, 1974.
29.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Conduction disorders in
the canine proximal His-Purkinje
system following acute myocardial ischemia. I. The pathophysiology of intra-His bundle block.
Circulation 49:837-847, 1974.
30.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Conduction disorders in the canine proximal His-Purkinje
system following acute myocardial ischemia. II. The pathophysiology of bilateral bundle branch block.
Circulation 49:848-857, 1974.
31.
El-Sherif, N. The mechanism of supraventricular tachycardia. Ectopic (parasystolic) focus versus re-entry.
J Electrocardiol. 7(2):169-178, 1974
32.
Scherlag, B.J., El-Sherif, N., Lazzara, R. An experimental model for the study of Mobitz type II and
paroxysmal A-V block. Amer. J. Cardiol 34:309-317, 1974.
33.
Lazzara, R., El-Sherif, N., Scherlag, B.J. Early and late effects of coronary occlusion on Purkinje fibers.
Circ. Res. 35:391-399, 1974.
34.
Hope, R.R., Williams, D.O., El-Sherif, N., Lazzara, R., Scherlag, B.J. The efficacy of antiarrthymic agents
during acute myocardial ischemia and the role of heart rate. Circulation 50:507-514, 1974.
35.
Scherlag, B.J. El-Sherif, N., Hope, R.R., Lazzara, R.: Characterization and localization of ventricular
arrhythmias due to myocardial ischemia and infarction. Circ. Res. 35:372-383, 1974.
11
36.
El-Sherif, N., Scherlag, B.J. Lazzara, R.R., Williams, D.O., Samet, P. The pathophysiology of
tachycardia-dependent paroxysmal A-V block after acute myocardial infarction. Experimental and clinical
observations. Circ. 50:515-528, 1974.
37.
Badran, A., El-Sherif, N., Fouad, F., Sorour, A.H. On the rehabilitation of rheumatic heart cases: A three
year study. J. Egypt. Public Health Assn. 49:69-82, 1974.
38.
Williams, D.O., Scherlag, B.J., Hope, R.R., El-Sherif, N., Lazzara, R. The pathophysiology of malignant
ventricular arrhythmias during acute myocardial ischemia. Circulation 50:1163-1172, 1974.
39.
Gann, D., Balachandran, P., El-Sherif, N., Samet, P. The prognostic significance of acute versus chronic
bundle branch block in acute
myocardial infarction. Chest 67:298-303, 1974.
40.
El-Sherif, N., Samad, A., Mascarhenas, E., Gann, D., Schoenfeld, C., Samet, P. Acute myocardial
infarction in the elderly. Influence of the coronary care unit on mortality. Chest 66:541-544, 1974.
41.
El-Sherif, N., Scherlag, B.J., Lazzara, R. The pathophysiology of second degree atrioventricular block.
A unified hypothesis. Amer. J. Cardiol. 35(3) 421-434, 1975.
42.
El-Sherif, N., Samet, P. Multiform ectopic rhythm. Evidence for multiple parasystolic activity. Circulation
51:492-505, 1975.
43.
Lazzara, R., El-Sherif, N., Scherlag, B.J. Disorders of cellular electrophysiology produced by ischemia of
the canine His bundle. Circ. Res. 36:444-454, 1975.
44.
Berbari, E.J., Lazzara, R., El-Sherif, N., Scherlag, B.J. Extracardiac recordings of His-Purkinje activity
during conduction disorders and junctional rhythms. Circulation 51:802-810, 1975.
45.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Electrode catheter recordings during malignant ventricular
arrhythmia following experimental acute myocardial ischemia. Evidence for reentry due to local
conduction delay and block in ischemia myocardium. Circulation 51:1003-1014, 1975.
46.
Aranda, J.M., Befeler, B., Lazzara, R., El-Sherif, N. The clinical spectrum of mitral valve prolapse. Bull.
Puerto Rico Medical Assn. 67:113-123, 1975.
47.
El-Sherif, N., Myerburg, R.J., Scherlag, B.J., Befeler, B., Aranda, J., Castellanos, A., Lazzara, R.
Electrocadiographic antecedents of primary ventricular fibrillation. Value of R-on-T phenomenon in
myocardial infarction. Brit. Heart J. 38:415-422, 1976.
48.
Williams, D.O., Scherlag, B.J., Hope, R.R., El-Sherif, N., Lazzara, R., Samet, P. Selective and nonselective His bundle pacing. Cardiovasc. Res. 10:91-100, 1976.
49.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Bradycardia-dependent conduction disorders. (Editorial) J.
Electrocardiol 9(1):1-4, 1976.
50.
Aranda, J.M., Befeler, B., Castellanos, A., El-Sherif, N. His bundle recordings. Their contribution to the
understanding of human electrophysiology. Heart and Lung 5(6):907-918, 1976.
51.
Aranda, J.M., Befeler, B., Lazzara, R., El-Sherif, N., Castellanos, A. Mitral valve prolapse: Recent
concepts and observations. Amer. J. Med. 60:997-1004, 1976.
52.
Lazzara, B., El-Sherif, N., Befeler, B., Scherlag, B.J. Regional refractoriness within the ventricular
conduction system - an evaluation of the "gate" hypothesis. Circ. Res. 39(2):254-262, 1976.
12
53.
Berbari, E.J., Scherlag, B.J., El-Sherif, N., Befeler, B., Aranda, J.M., Lazzara, R. The His-Purkinje
electrocardiogram in man. An initial assessment of its uses and limitations. Circulation 54(2): 219-224,
1976.
54.
El-Sherif, N., Befeler, B., Aranda, J.M., Castellanos, A., Lazzara, R. Reentry due to manifest and
concealed His bundle ectopic systoles. Circulation 53(5):902-908, 1976.
55.
El-Sherif, N., Scherlag, B.J., Lazzara, R. An appraisal of second degree and paroxysmal atrioventricular
block. European J. Cardiology 4/2:117-130, 1976.
56.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Second degree atrioventricular block in the His-Purkinje system
following acute myocardial infarction. Clinical observations on its evloution. Chest 71:615-623, 1977.
57.
Hope, R.R., Scherlag, B.J., El-Sherif, N., Lazzara, R. Hierarchy of ventricular pacemakers. Circ. Res.
39(6):883-888, 1976.
58.
Befeler, B., Aranda, J.M., Embi, A., Mullin, F.S., El-Sherif, N., Lazzara, R.L. Coronary artery aneurysms.
Study of their etiology, clinical course, and effect on left ventricular function and prognosis. Am. J. Med.
62:597-607, 1977.
59.
Aranda, J.M., Befeler, B., Thurer, R., Vargas, A., El-Sherif, N., Lazzara R. Long-term clinical and
hemodynamic studies after ventricular aneurysmectomy and aorto-coronary bypass. J. Thorac.
Cardiovas. Surgery 73:772-779, 1977.
60.
Hope, R.R., Scherlag, B.J., El-Sherif, N., Lazzara, R. R/T phenomenon: A time for re-appraisal. Aust. &
N.Z. J. Med. 7:109-110, 1977.
61.
El-Sherif, N., Scherlag, B.J., Lazzara, R., Hope, R.R. Reentrant ventricular arrhythmias in the late
myocardial infarction period. 1. Conduction characteristics in the infarction zone. Circulation 55:686702, 1977.
62.
El-Sherif, N., Hope, R.R., Scherlag, B.J., Lazzara, R. Reentrant ventricular arrhythmias in the late
myocardial infarction period. 2. Patterns of initiation and termination of reentry. Circulation 55: 702-719,
1977.
63.
El-Sherif, N., Lazzara, R., Hope, R.R., Scherlag, B.J. Reentrant ventricular arrhythmias in the late
myocardial infarction period. 3. Manifest and concealed extrasystolic gruping. Circulation 56: 225-234,
1977.
64.
El-Sherif, N., Sherlag, B.J., Lazzara, R., Hope, R.R. Reentrant ventricular arrhythmias in the late
myocardial infarction period. 4. Mechanisms of action of lidocoaine. Circulation 56:395-402, 1977.
65.
Hope, R.R. Scherlag, B.J. El-Sherif, N., Lazzara, R. Continuous concealed ventricular arrhythmias. Am.
J. Cardiol. 40:733-738, 1977.
66.
El-Sherif, N., Lazzara, R. Reentrant ventricular arrhythmias in late myocardial infarction period.
Mechanism of action of diphenlhydantoin.
Circulation 57:465-472, 1978.
67.
El-Sherif, N., Amat-Y-Leon, F., Schonfield, C., Scherlag, B.J, Rosen, K., Lazzara, R., Wyndham, C.
Normalization of bundle branch block patterns by distal His bundle pacing. Clinical and experimental
evidence of longitudinal dissociation in the pathologic His bundle. Circulation 57:473-483, 1978.
5.
13
68.
Lazzara, R., El-Sherif, N., Hope, R.R., Scherlag, B.J. Ventricular arrhythmias and electrophysiologic
consequences of ischemia and infarction. Circ Res 42:740-749, 1978.
69.
El-Sherif, N., Aranda, J., Befeler, B., Lazzara, R. Atypical Wenckebach periodicity simulating Mobitz II
A-V block.
Brit. Heart J. 40:1376-1383, 1978.
70.
Mendoza, I., Scherlag, B.J., El-Sherif, N., Lazzara, R., Hope, R. Lesiones del haz de His. Correlacion
clinica y experimental. Archivos Del Instituto De Cardiologia De Mexico 50:132-140, 1978.
71.
Lazzara, R., El-Sherif, N., Hope, R., Scherlag, B.J. The effects of lidocainine on hypoxic and ischemic
cardiac cells. Am. J. Cardiol. 41:872-879, 1978.
72.
Hope, R.R., Scherlag, B.J., El-Sherif, N., Lazzara, R. Ventricular arrhythmias in healing myocardial
infarction. J. Thorac. Cardiovsc. Surg. 75:458-466, 1978.
73.
Richter, S., Aranda, F.A., Vargas, A., El-Sherif, N., Befeler, B. Functional significance of
electrocardiographic changes after left ventricular aneurysmectomy. J. Electrocardiol. ll(3):247-252, 1978.
74.
El-Sherif, N. Reentrant ventricular arrhythmias in the late myocardial infarction period. 6. Role of the
autonomic system. Circulation 58: 103-110, 1978.
75.
Waxman, H.L., Lazzara, R., El-Sherif, N. Apparent malfunction of demand pacemakers due to spurious
potentials generated by contact between two endocardial electrodes. Pace 1:531-534, 1978.
76.
Scherlag, B.J., Lazzara, R., Hope, R.R., El-Sherif, N. The significance of dissociation of conduction in
the canine His bundle. Electrophysiologic studies in vivo and in vitro. J Electrocardiol. ll(4):343-354,
1978.
77.
El-Sherif, N., Lazzara, R.:Reentrant ventricular arrhythmias in the late myocardial infarction period.7:
Effect of verapamil and D-600 and role of the "slow channel". Circulation 60:605-615, 1979
78.
Waxman, H.J., Lazzara, R., Castellanos, A., El-Sherif, N. Ventricular pacing from the middle cardiac vein
mimiking supraventricular morphology. Pace 2:203-207, 1979.
79.
Kang, P.S., Gomes, J.A.C., El-Sherif, N.: Ventricular tachycardia
(RSR pattern) in Vl. Chest 77: 666-668, 1980.
80.
Kelen, G., Bloomfield, D.A. Hardage, M. Gomes, J.A.C., Khan, R., Gopalaswamy, C., El-Sherif, N.:
A clinical evaluation of an improved Holter monitoring technique for artificial pacemaker function. Pace
3:192-197, 1980.
81.
Khan, R., Amaram, S., Gomes, J.A.C., Kelen, G., Lynfield, J., El-Sherif, N.:
Myocardial infarction
following acute aortic dissection.
Catheterization and Cardiovascular Diagnosis 6:180-184, 1980.
82.
Gomes, J.A.C., Kang, P.S., Kelen, G., Khan, R., El-Sherif, N.: Simultaneous antegrade fast-slow AV
nodal pathway.
Conduction following procainamide. Am J. Cardiology 46:667-684, 1980.
83.
Gomes, J.A.C., Kang, P.S., Matheson, M., El-Sherif, N.: Coexistence of sick sinus rhythm and atrial
flutter-fibrillation. Circulation 63:80-86, 1981.
84.
El-Sherif, N., Smith, R.A., Evans, K.: Canine ventricular arrhythmias
in the late myocardial infarction
period. 8. Epicardial mapping of reentrant circuits. Circulation Res. 49:255-265, 1981.
with classic triphasic morphology
14
85.
Gomes, J.A.C., Kang, P.S., Khan, R., Kelen, G., El-Sherif, N.: Repetitive ventricular response. Its
incidence, inducibility, reproducibility, mechanism and significance. Brit Heart J 46:152-159, 1981.
86.
Kang, P.S., Gomes, J.A.C., Kelen,G., El-Sherif, N.: Role of autonomic regulatory mechanisms in
sinoatrial conduction and sinus node automaticity in sick sinus syndrome. Circulation 64:833-841, 1981.
87.
Gomes, J.A.C., Kang, P.S., El-Sherif, N.: The Effects of digitalis on the human sick sinus node after
pharmacologic autonomic blockade. Am. J. Cardiol. 48:783-788, 1981.
88.
Kang, P.S., Gomes, J.A.C., El-Sherif, N. Procainamide in the induction and perpetuation of ventricular
tachycardia in man.
Pace 5:311-322, 1982.
89.
Kang, P.S., Gomes, J.A.C., El-Sherif, N. Differential effects of functional autonomic blockade on the
variables of sinus nodal automaticity in sick sinus syndrome. Am. J. Cardiol. 49:273-282, 1982.
90.
Mehra, R., Kelen, G.J., Zeiler, R.H., Zehiran, D., Fried, P., Gomes, J.A.C., El-Sherif, N.: Non-invasive
His Bundle electrogram: Value of three vector lead recordings. Am. J. Cardiol. 49:344-348, 1982.
91.
Gough, W.B., Zeiler, R.H., Barreca, P., El-Sherif, N.: Hypotensive action of commercial intravenous
amiodarone and polysorbate 80 in dogs. J. Cardiovasc. Pharmacology 4:375-380, 1982.
92.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.H.: Ventricular activation patterns of spontaneous and
induced ventricular rhythms in canine one-day-old myocardial infarction. Evidence for focal and reentrant
mechanisms. Circ. res. 51:152-166, 1982.
93.
Gomes, J.A.C. Kang, P.S., Mehra, R., El-Sherif, N. The sinus node electrogram in patients with and
without sick sinus syndrome: Techniques, correlation between directly measured and indirectly estimated
sinus-atrial conduction time. Circulation 66:864-873, 1982.
94.
Zeiler, R.H., Srand, F.L., El-Sherif, N. Electrophysiology and Contractile responses of canine atrial tissue
to adrenocorticotropin. Peptides, 3:815-822, 1982.
95.
Mehra, R., El-Sherif, N.: Signal averaging of electrocardiographic potentials: A review. Acupuncture and
Electro-Therapeutics Res., Int. J. 7:133-155, 1982.
96.
Mehra, R., Zeiler, R.H., Gough, W.B. El-Sherif, N.: Reentrant ventricular arrhythmias in the late
myocardial infarction period. 9. Electrophysiological-anatomical correlation of reentrant circuits.
Circulation, 67(1) 11-24, 1983.
97.
El-Sherif, N., Mehra, R., Gomes, J.A.C., Kelen, G.: Appraisal of a low noise electrocardiogram. J. Amer.
Coll. Cardiol. (2) 456-67, 1983.
98.
Feit, A., Korostoff, S., El-Sherif, N. Chagas' disease masquerading as coronary artery disease. Arch. Int.
Med. 134:144-145, 1983.
99.
Hariman, R.J., Gomes, J.A.C., El-Sherif, N. Catecholamine-dependent AV nodal reentrant tachycardia.
Circulation 67:681-686, 1983.
100.
Chowdry, I.H., Hariman, R.J., Gomes, J.A.C., El-Sherif, N. Transient digitoxic double tachycardia. Chest,
Vol. 83, p.686-687, 1983.
101.
Reddy, C.V.R.,, Khan, R., Feit, A., Gordon, D., El-Sherif, N.: Catheter Separation during coronary
angiography. J. Cath. and Cardiovas. Diag. 9(4):417-419, 1983.
15
102.
Lorenz, J, Khan, R., Reddy, C.V.R., Hoover, E., Hsu, H.K., El-Sherif, N.:
shunt following valve replacement. Chest. 83:922-925, 1983.
Aortico-right ventricular
103.
El-Sherif, N., Gough, W.B., Zeiler, R.H., Mehra, R.: Triggered ventricular rhythms in 1-day-old
myocardial infarction in the dog. Cir. Res. Vol. 52 (5), pp 566-579, 1983.
104.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.H.: Reentrant ventricular arrhythmias in the late
myocardial infarction period. Interruption of reentrant circuits by cryothermal techniques. Circulation 68
(3) 644-656, 1983.
105.
Reddy, C.V.R., Kiok, J.p., Khan, R.G., El-Sherif, N.: Repolarization alternans associated with alcoholism
and hypomagnesemia. Amer J Cardiol 53:390-391,1984.
106.
Gomes, J.A.C, Kang, P.S., Hariman, R., Lyons, J. El-Sherif, N.: Electrophysiologic effects and
mechanism of termination of supraventricular tachycarida by intravenous amiodrone. Am Heart Journal.
Vol 107 (2) 214-221, 1984.
107.
Hariman, R.J., Gomes, J.A.C., Kang, P.S., El-Sherif, N.: Effects of intravenous amiodrone in patients
with inducible repetitive ventricular tachycardia. Am Heart Journal. 107:1109-1117, 1984.
108.
Gough, W.B., Zeiler, R.H., El-Sherif, N.: Effects of diltiazem on triggered activity in canine one-day-old
infarction. Cardiovasc Res 18:339-343, 1984.
109.
Gough, W.B., Zeiler, R.H., El-Sherif, N.: Effects of nifedipine on triggered activity in one-day-old
infarction in dog. Am J of Cardiol. 53:303-306, 1984.
110.
Hariman, R.J., Gomes, J.A.C., El-Sherif,N.: Recording of diastolic slope with catheters during junctional
rhythm in humans. Circulation 69: (3) 485-491, 1984.
111.
Pasquariello, J.L., Hariman, R.J., Feit, A., Gomes, J.A.C., El-Sherif, N.: Recurrent pulmonary
embolization following implantation of transvenous pacemaker. PACE Vol 7 (V), 790-793, 1984.
112.
Feit, A., Khan, R., Reddy, C.V.R., Chowdry, I, Blanche, C., Piccone, V., El-Sherif, N.: Coronary artery
dissection secondary to coronary angiography. Cath. and Cardiovas. Diag. 10:177-181, 1984.
113.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.H.: Reentrant ventricular arrhythmias in the late
infarction period. Burst pacing versus multiple premature stimulation. J. Amer Coll Cardiol 4(2): 295-304,
1984.
114.
Feit, A., Khan, R., El-Sherif, N., Reddy, C.V.R.: The Non random occurrence of single vessel coronary
artery disease. Amer. J. of Med. 77:683, 1984.
115.
Gomes, J.A.C., Hariman, R.J., Kang, P., Chowdry, I., Lyons, J., El-Sherif, N.: Programmed cardiac
stimulation in patients with high grade ectopy. Electrophysiologic findings and prognosis for survival.
Circulation 70:43-51, 1984.
116.
Zeiler, R.H., Gough, W.B., El-Sherif, N.: Electrophysiologic Effects of Propafenone on Canine Ischemic
Cardiac Cells. Am. J. Cardiol 54: 424-429, 1984.
117.
Bishara, N., Hariman, R.J., Gomes, J.A.C., El-Sherif, N.: Asynchronized direct-current electrical energy
causing acceleration of ventricular tachycardia. Critical Care Medicine 12:1001, 1984.
16
118.
Feit, A., Reddy, C.V.R., Khan, R., Meilman, H., El-Sherif, N.: The changed learning curve for
percutaneous transluminal coronary angioplasty: Implications for the future treatment of coronary artery
disease. Am J Med. 78:438-442, 1985.
119.
Feit, A., Holtzman, R., Cohen, M., El-Sherif, N.: The effect of Labetalol on exercise tolerance and double
product in mild to moderate essential hypertension.
Am J Med. 78:937-941, 1985.
120.
Hariman, R.S., Zeiler, R.H., Gough, W.B., El-Sherif, N.: Enhancement of triggered activity in ischemic
Purkinje fibers by ouabain. A mechanism of increased suceptibility to digitalis toxicity in myocardial
infarction. J Am Coll Cardiol 5:672, 1985.
121.
El-Sherif, N., Gomes, J.A.C., Restivo, M., Mehra, R.: Late potentials and arrhythmogensis. PACE 8: 440462, 1985.
122.
El-Sherif, N., Gough, W.B., Zeiler, R.H., Hariman, R.: Reentrant ventricular arrhythmias in the late
myocardial infarction period. 12. Spontaneous versus induced reentry and intramural versus epicardial
circuits. J Am Coll Cardiol. 6: 124-132, 1985.
123.
Feit, A., Sedlis, S., Khan, R., Reddy, C.V.R., El-Sherif, N.: The radiographic appearance of arterial sheath
kinking. Cath. & Cardiovasc. Diag. 11:283-285, 1985.
124.
Gomes, J.A., Mehra, R., Barreca, P., El-Sherif, N., Hariman, R., Holtzman, R.:Quantitave analysis of the
high-frequency components of the signal-averaged QRS complex in patients with acute myocardial
infarction: A prospective study. Circulation 72:105-111, 1985.
125.
Gough, W.B., Mehra, R., Restivo, M., Zeiler, R.H., El-Sherif, N.: Reentrant ventricular arrhythmias in the
late myocardial infarction period. 13. Correlation of activation and refractory maps. Circ Res. 57:432-442,
1985.
126.
Hariman, R.J., Pasquariello, J.L., Gomes J.A.C., Holtzman, R., El-Sherif, N.: Autonomic Dependence of
Ventricular-Atrial Conduction. Am J Cardiol. 56:285-291, 1985.
127.
Hoover, E.L., Hsu, H.K, Diaz, C., Khan, R., Reddy, C.V.R., Gross, A.M., Webb, H., El-Sherif, N.,
Griepp, R.B.: Surgical management of synchronous cornary artery disease and multiple aortic stenosis: A
case report with brief review of the literature. Texas Heart Institute Journal 12:187-193, 1985.
128.
Sedlis, S.P., Macina, A., Khan, R.G., El-Sherif, N.: Left main coronary artery spasm following
precutaneous transluminal coronary angioplasty. Cath. & Cardiovas. Diag. 12 (3):162, 1986.
129.
Craelius, W., Restivo, M., Assadi, M., El-Sherif, N.: Criteria for Optimal Averaging of Cardiac Signals.
IEEE Trans Biomed Eng. 33: 957-966, 1986.
130.
Craelius, W., Chen, V., Restivo, M., El-Sherif, N.: Rhythm Analysis of Arterial Blood Pressure. IEEE
Trans Biomed Eng 33:1166-1172, 1986.
131.
The Solu-Medrol AMI studies group: Methyl prednisolone as an intervention following myocardial
infarction. J Int Med Res 14 (Suppl 1):1-10, 1986.
132.
El-Sherif, N., Mehra, R., Restivo, M., Kelen, G.: A low noise P-wave discriminating electrocardiogram in
the diagnosis of complex cardiac arrhythmias. Am J Cardiol 59:173-175, 1986.
133.
Lopressor Intervention Trial Research Group: The Loperessor Intervention Trial: Multicenter study of
Metoprolol in survivors of acute myocardial infarction. Eur Heart J 8:1056-64,1987.
17
134.
El-Sherif, N., Gough, W.B., Restivo, M.: Reentrant ventricular tachycardia in the late myocardial
infarction period. 14. Mechanisms of resetting, entrainment, acceleration or termination of reentrant
tacycardia by programmmed electrical stimulation. PACE 10:341-371, 1987.
135.
Craelius, W., Restivo, M., El-Sherif, N.: Signal Processing Options for Ischemic Cardiac Potentials. J
Electrocardiology, 20 (Supplemental issue):119-124, 1987.
136.
Macina, G., Turitto, G., Stavens, C., Fontaine, J., Hariman, R., Ursell, S., El-Sherif, N.:
Antiarrhythmic effects of oral, indecainide in patients with ventricular tachyarrhythmias. Clin Cardiol
10:357-361, 1987.
137.
Kelen, G., Henkin, R., Fontaine, J., El-Sherif, N.: Effects of analyzed signal duration and phase on the
results of Fast Fourier Transform Analysis of the surface electrocardiogram in subjects with and without
late potentials. Am J Cardiol.60:1282-1289, 1987.
138.
Evans GT Jr, Scheinman MM, Zipes DP,Benditt D, Breithardt G, Camm AJ, El-Sherif N, Fisher J,
Fontaine G, Levy S, Prystowsky E, Josephson M, Morady F, Ruskin J. The Percutaneous Cardiac
Mapping and Ablation Registry: summary of results. PACE 1987;10:1395-1399.
Bekheit, S., Turitto, G., Fontaine, J., El-Sherif, N.: Initiation of ventricular fibrillation by supraventricular
beats in patients with acute myocardial infarction. Brit Heart J. 59:190-195, 1988.
139.
140.
Sedlis ST, Cohen KH, Sequeira JM, El-Sherif N: Preservation of left ventricular function in patients with
total occlusion of the left anterior descending coronary artery and wide caliber distal vessels filling by
collateral vasculature. Catheterization & Cardiovascular Diagnosis 15:139-142, 1988.
141.
Gough, W.B., Hu, D., El-Sherif, N,: Effects of clofilium on ischemic subendocardial Purkinje fibers one
day post-infarction. J Am Coll Cardiol. 11:431-437, 1988.
142.
Turitto, G., El-Sherif, N.: Alternans of ST segment in variant angina: Incidence, time course and relation
to ventricular arrhythmias during ambulatory electrocardiographic recording. Chest. 93:587-591, 1988.
143.
Restivo, M., Gough, W.B., El-Sherif, N.: Reentrant ventricular arrhythmias in the late myocardial
infarction period: Prevention of reentry by dual stimulation during basic rhythm. Circulation 77: 429-444,
1988.
144.
Turitto, G., Fontaine, J.M., Ursell, S.N., Caref, E.B., Henkin, R., El-Sherif, N.: Value of the signal
averaged electrocardiogram as a predictor of the results of programmed stimulation in non-sustained
ventricular tachycardia. Amer J Cardiol. 61:1272-1278, 1988
145.
Turitto, G., Caref, E.B., Macina, G., Fontaine J.M., Ursell, S.N., El-Sherif, N.: Time course of ventricular
arrhythmias and the signal averaged electrocardiogram in the post-infarction period: A prospective study
of correlation. Brit Heart J. 60: 17-22, 1988.
146.
Evans GR, Scheinman MM, Zipes DP, Benditt D, Breithardt G, Camm AJ, El-Sherif N, Fisher J, Fontaine
G, Levy S, Prystowsky E, Josephson M, Morady F, Ruskin J: The percutaneous cardiac mapping and
ablation registry: Final summary of results. PACE 11:1621, 1988.
147.
El-Sherif, N., Zeiler, R.H., Craelius, W., Gough, W.B., Henkin, R.,: QTU prolongation and polymorphic
ventricular tachyarrythmias due to bradycardia-dependent early afterdepolarizations. Circ Res. 63:286 305, 1988.
148.
Craelius, W., Chen, V., El-Sherif, N.: Stretch activated ion channels in ventricular myocytes. Bioscience
Reports 8(5):407-414, 1988.
18
149.
Fontaine, JM, Alma-Perri, C, El-Sherif, N.: DDD Pacemaker pseudo malfunction during supraventricular
tacycardia.
Pace 11:1380-1385, 1988.
150.
Sedlis SP, Sequeira JM, Ahumada GC, El-Sherif N: Effects of lysophosphatidylcholine on cultured heart
cells: Correlation of rate of uptake and accumulation with cell injury.
J Lab Clin Med. 112:745-54,
1988.
151.
Hariman RJ, Dayi H, Beckman KJ, Gomes JAC, Bauman JL, El-Sherif N: Cryothermal mapping of the
sinus node in dogs: a simple method of localizing dominant and latent pacemakers. Cardiovasc
Res.23:231-238, 1989.
152.
Gough WB, El-Sherif N: The differential response of normal and ischaemic Purkinje fibers to clofilium,
d-sotalol and bretylium. Cardiovasc Res. 23:554-559, 1989.
153.
El-Sherif N, Bekheit S, Henkin R: Quinidine induced long QTU and Torsade de Pointes. Role of
bradycardia-dependent early afterdepolarizations. J Amer Coll Cardiol. 14:252-257, 1989.
154.
Kelen G, Henkin R, Lannon M, Bloomfield D, El-Sherif N:Correlation between the signal-averaged
electrocardiogram from Holter tapes and from real-time recordings. Am J Cardiol. 63:1321-1325, 1989.
155.
Caref EB, Turitto G, Ibrahim B, Henkin R, EL-Sherif N: Role of bandpass filters in optimizing the value
of the signal averaged electrocardiogram as a predictor of the results of programmed stimulation. Am J
Cardiol. 64:16-26, 1989.
156.
El-Sherif N, Ursell SN, Bekheit S, Fontaine J, Turitto G, Henkin R, Caref EB:
Prognostic significance
of the signal averaged electrocardiogram depends on the time of recording in the post-infarction period.
Am Heart J. 118:256-264, 1989.
157.
Craelius W, El-Sherif N, Palant CP: Stretch activated channels in mesangial cells. Biochem Biophys Res
Comm. 159:516-521, 1989.
158.
The Cardiac Arrhythmia Suppression Trial (CAST) Investigators: Preliminary report: Effect of encainide
and flecainide on mortality in randomized trial of arrhythmia suppression after myocardial infarction. New
Engl J Med 321:406-412, 1989.
159.
Gough WB, El-Sherif N: Dependence of delayed afterdepolarizations on diastolic potentials in ischemic
Purkinje fibers.
Am J Physiol. 257:H770-H777, 1989.
160.
Bekheit S, Tangella M, El-Sakr A, Rasheed Q, Craelius W, El-Sherif N: Use of heart rate spectral analysis
to study the effects of calcium channel blockers on sympathetic activity after myocardial infarction. Am
Heart J 119:79-85, 1990.
161.
Turitto G, Fontaine JM, Ursell S, Caref EB, Bekheit S, El-Sherif N: Risk stratification and management of
patients with organic heart disease and non-sustained ventricular tachycardia:Role of programmed
stimulation, left ventricular ejection fraction and the signal averaged electrocardiogram. Am J Med. 88:135N-1-41N, 1990.
162.
Henkin R, Caref EB, Kelen GJ, El-Sherif N: The signal averaged electrocardiogram: A comparative
analysis of commercial devices. J Electrocardiol. 22 (Suppl 1) 19-24, 1990.
163.
Boutjdir M, El-Sherif, Gough WB:The effects of caffeine and ryanodine on delayed afterdepolarizations
and sustained rhythmic activity in one day old infarction in the dog. Circulation 81:1393-1400, 1990.
19
164.
Restivo M, Craelius W, Gough WB, El-Sherif N: A logical state model of reentrant ventricular
activation.
IEEE Trans Biomed Eng 37(4):344-353, 1990.
165.
Habbab M, El-Sherif N: Drug-induced Torsade de Pointes. Role of early afterdepolarizations and
dispersion of repolarization. Am J Med. 89:241-246, 1990.
166.
Assadi M, Restivo M, Gough WB, El-Sherif N: Reentrant ventricular arrhythmias in the late myocardial
infarction period. Correlation of activation patterns of sinus and reentrant ventricular tachycardia. Am
Heart J 119:1014-1024, 1990.
167.
Bekheit S, Restivo M, Boutjdir M, Henkin R, Gooyandeh K, Assadi M, Khatib S, Gough WB, El-Sherif
N: Effects of Glyburide on ischemia-induced changes in extracellular potassium and local myocardial
activation. A potential new approach to the management of ischemia-induced malignant ventricular
arrhythmias. Am Heart J 119:1025-1033, 1990.
168.
Caref EB, Goldberg N, Mendelson L, Hanley O, Okereka R, Stein R, El-Sherif N: Effects of exercise on
the signal averaged electrocardiogram in patients with coronary artery disease. Am J Cardiol 66:54-58,
1990.
169.
Restivo M, Gough WB, El-Sherif N: Ventricular arrhythmias in the sub-acute myocardial infarction
period: High resolution activation and refractory patterns of reentrant rhythms. Circ Res 66:1310-1327.
1990.
170.
Schoels W, Gough WB, El-Sherif N: Circus movement atrial flutter in the canine sterile pericarditis
model: Activation patterns during initiation, termination and sustained reentry in vivo. Circ Res 67:35-50,
1990.
171.
Amitzur G, El-Sherif N, Gough WB: Electrophysiological effects of a chemical defibrillatory agent:
Dibenzepin. J Cardiovasc Res. 24:781-785, 1990.
172.
El-Sherif N, Gough WB, Restivo M: Reentrant ventricular arrhythmias in the late myocardial infarction
period. The mechanism by which a short-long-short cardiac sequence facilitates the induction of reentry.
Circulation. 83:268-278, 1991.
173.
Fontaine JM, Rao R, Henkin R, Suneja R, Ursell SN, El-Sherif N: A study of the influence of left bundle
branch block on the signal averaged electrocardiogram: A qualitative and quantitative analysis. Am
Heart J. 121:494-508, 1991.
174.
Turitto G, Caref EB, Zanchi E, Menghini F, Kelen G, El-Sherif N: Spontaneous myocardial ischemia and
the signal-averaged electrocardiogram. Am J Cardiol 67:676-680, 1991.
175.
Kelen G, Henkin R, Starr A-M, Caref EB, Bloomfield D, El-Sherif N: A spectral turbulence analysis
technique for improved predictive accuracy for induced sustained monomorphic ventricular tachycardia.
Am J Cardiol 67:965-975, 1991.
176.
Schoels W, Restivo M, Caref EB, Gough WB, El-Sherif N: Circus movement atrial flutter in the canine
sterile pericarditis model: Activation patterns during entrainment and termination of single loop reentry in
vivo. Circulation 85:1716-1730, 1991.
177.
Boutjdir M, El-Sherif N: Alpha1-adreno receptor regulation of delayed afterdepolarizations and triggered
activity in subendocardial Purkinje fibers surviving 1 day of myocardial infarction. J Mol Cell Cardiol
23:83-90. 1991.
20
178.
Schoels W, Yang H, Gough WB, El-Sherif N: Circus movement atrial flutter in the sterile pericarditis
model: Differential effects of procainamide on the components of the reentrant pathway. Circ Res
68:1117-1126, 1991.
179.
Boutjdir M, El-Sherif N: Pharmacological evaluation of early afterdepolarizations induced by sea
anemone toxin (ATXII) in dog heart. Cardiovasc Res. 25:815-819,1991.
180.
Feit A, Cohen M, Dimino L, El-Sherif N, Holtzman R, Ram CVS, Gaffney D, Heller JA, Kaplan N : The
effects of labetalol and prazosin on excercise haemodynamics in hypertensive patients. J Human
Hypertension 5:39-43,1991.
181.
Capone RJ, Pawitan Y, El-Sherif N, Geraci TS, Handshaw K, Morganroth J, Schlant R, Waldo A: Events
in the Cardiac Arrhythmia Suppression Trial: Baseline predictors of mortality in placebo patients. J Am
Coll Cardiol 18:1434-1438, 1991.
182.
El-Sherif N, Fozzard HA, Hanck DA: Dose-dependent modulation of the cardiac sodium channel by the
sea anemone toxin ATXII. Circ Res. 70:285-301,1992.
183.
Habbab MA, El-Sherif N: TU alternans, long QTU, and torsade de pointes . Clinical and experimental
observations. Pace 15: 915-931, 1992.
184.
Habbab MA, El-Sherif N : Recordings from the slow zone of reentry during burst pacing versus
programmmed premature stimulation for the initiation of reentrant ventricular tachycardia in patients with
coronary artery disease. Am J Cardiol 70:211-217,1992.
185
The Cardiac Arrhythmias Suppression Trial II Investigaters: Effect of the antiarrhythmic agent moricizine
on survival after myocardial infarction. N Eng J Med 327:227-233,1992.
186.
Butrous G,Gough WB, Restivo M, Yang H, El-Sherif N: Adrenergic effects on reentrant ventricular
rhythms in subacute myocardial infarction. Circulation 86:247-254, 1992.
187.
Boutjdir M, Restivo M, Wei Y, El-Sherif N: Alpha 1-adrenergic inhibition of calcium current stimulated
through -adrenoceptors in cardiac myocytes. Pflugers Arch 421:397-399, 1992.
188.
Boutjdir M. Morgenstern D, Wei Y, Restivo M, El-Sherif N, Siddiqui MAQ: Changes in sacrolemmal
proteins in subacute myocardial infarction in the dog. Cell & Mol Biol. 38(6):571-585, 1992.
189.
Schoels W, Kuebler W, Yang H, Gough WB, El-Sherif N: A unified functional/anatomic substrate for
circus movement atrial flutter: Activation and refractory patterns in the canine right atrial enlargement
model. J Am Coll Cardiol 21:73-84, 1993.
190.
Bekheit S, Isber N, Jani H, Butrous G, Boutjdir M, El-Sherif N: Improvement of ischemia-induced
electrophysiological abnormalities by glucose-insulin infusion. J Am Coll Cardiol 22:1214-1222, 1993.
191.
Isber N. Restivo M, Gough WB, Yang H, El-Sherif N: Circus movement atrial flutter in the canine sterile
pericarditis model. Cryothermal termination from the epicardial site of the slow zone of the reentrant
circuit. Circulation 87:1649-1660, 1993
192.
Schoels W, Offner B, Brachmann J, Kuebler W, El-Sherif N: Circus movement atrial flutter in the sterile
pericarditis model. Relation of characteristics of the surface electrogram and conduction properties of the
reentrant pathway. J Am Coll Cardiol 23:799-808,1994.
193.
Turitto G, Ahuja R, Bekheit S, Caref EB, Ibrahim B, El-Sherif N: Incidence and prediction of induced
ventricular tachyarrhythmias in idiopathic dilated cardiomyopathy. Am J Cardiol 73:770-773,1994.
21
194.
Denes P, El-Sherif N, Katz R, Capone R, Carlson M, Mitchell LB, Ledingham R for the Cardiac
Arrhythmia Suppression Trial (CAST) SAECG Substudy Investigators: Prognostic significance of signal
averaged electrocardiogram after thrombolytic therapy and/or angioplasty during acute myocardial
infarction. Am J Cardiol In press.
195.
Yang H, El-Sherif N, Isber N, Restivo M: A logical state model of circus movement atrial flutter, role of
anatomic obstracles, anisotropic conduction and slow conduction zones on induction, sustenance, and
overdrive paced modulation of reentrant circuits. IEEE Trans Biomed Eng.41:537-548,1994.
196.
Masrani K, Cowley C, Bekheit S, El-Sherif N: Recurrent syncope for over a decade due to idiopathic
ventricular fibrillation. Chest. 106:1601-1603, 1994.
197.
Boutjdir M, Restivo M, Wei Y, Stergiopolis K, El-Sherif N: Early afterdepolarization formation in cardiac
myocytes: Analysis of phase plane patterns, action potential, and membrane currents. J Cardiovas
Electroph 5:609-620, 1994.
198.
Turitto G, Ahuja RK, Caref EB, El-Sherif N: Risk stratification for arrhythmic events in patients with
nonischemic dilated cardiomyopathy and nonsustained ventricular tachycardia: Role of programmed
ventricular stimulation and the signal averaged electrocardiogram. J Am Coll Cardiol 24: ,1994.
199.
Turitto G, Rao S, Caref EB, El-Sherif N: Time and frequency domain analysis of the signal averaged
electrocardiogram in patients with ventricular tachycardia and ischemic versus nonischemic dilated
cardiomyopathy. J Electrocardiol. 27 (Suppl) 213-218, 1994.
200.
Ahuja RK, Turitto G, Ibrahim BB, Baref EB, El-Sherif N: Combined time-domain and spectral turbulence
analysis of the signal averaged electrocardiogram improves its predictive accuracy in post-infarction
patients. J Electrocardiol. 27 (Suppl) 202-206, 1994.
201.
Zhang Z-H, Boutjdir M, El-Sherif N: Ketanserin inhibits depolarization-activated outward potassium
current in rat ventricular myocytes. Circ Res. 75:711-721, 1994.
202.
El-Sherif N, Denes P, Katz R, Capone R, Mitchell B, Carlson M, Reynolds-Haertle R: Definition of the
best prediction criteria of the time-domain signal-averaged electrocardiogram for serious arrhythmic
events in the postinfarction period. J Am Coll Cardiol 25:908-914, 1995.
203.
Restivo M, Yin H, Caref EB, Patel AI, Ndrepepa G, Aviatable MJ, Assadi MA, Isber N, El-Sherif N:
Rentrant arrhythmias in the substrate infarction period. The proarrhythmic effect of flecainide acetate on
functional reentrant circuits. Circulation 91:1236-1246, 1995.
204.
Ndrepepa G, Caref EB, Yin H, El-Sherif N, Restivo M: Activation time determination by high resolution
unipolar and bipolar extracellular electrograms in the canine heart. J Cardiovas Electrophys.6:174-188,
1995.
205.
Vasquez R, Caref EB, TorresF, Reina M, Ortega F, El-Sherif N: Short-term reproducibility of time
domain, spectral temporal mapping, and spectral turbulance analysis of the signal-averaged
electrocariogram in normal subjects and patients with acute myocardial infarction. Am Heart J 130: 10111019, 1995.
206.
Boutjdir M, Assadi M, El-Sherif N: Electrophysiologic affects of cocaine on endocardial Purkinje fibers
surviving 1-day of myocardial infarction. J. Cardiovasc Electrophysiol 6: 729-736, 1995.
22
207.
Gidhi Jain M, Huang B, Japin P, Battula V, El-Sherif N: Re-emergence of the fetal patern of L-type
calcium current gene expression in non-infarcted myocardium during left ventricular remodeling.Biochem
Biophys Res Comm. 216:829-897, 1995.
208.
El-Sherif N, Yin H, Restivo M, Caref EB: Elecrophysiologic mechanisms of spontaneous termination of
sustained reentrant monomorphic ventricular tachycardia in the canine post-infarction heart. Circulation.
93:1567-1578, 1996.
209.
Turitto G, Mansoor S, Rao S, Caref EB, El-Sherif N: A comparative analysis of commercial software for
signal averaged electrocardiography. Annals Noninvasive Electrocardiography, 1:147-150, 1996.
``
210.
Chen L, El-Sherif N, Boutjdir M: 1 adrenergic activation inhibits -adrenergic stimulated unitary
calcium current in cardiac ventricular myocytes. Cir. Res. 79:184-193, 1996
211.
Qin D, Zhang Z-H, Caref EB, Boutjdir M, Jain P, El-Sherif N: Cellular and ionic basis of arrhythmias in
post-infarcton remodeled ventricular myocardium. Circ. Res, 79:461-473, 1996.
212.
El-Sherif N, Caref EB, Yin H, Restivo M: The electrophysiological mechanism of ventricular
tachyarrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns.
Circ Res 79:474-492, 1996
213.
Restivo M, Hegazy M, Caref EB, Avitable MJ, Assadi MA, El-Hamami M, Yin H, Piracha M, Brooks
RR, El-Sherif N: Effects of azimilide dihydrochloride on circus movement atrial flutter in the canine
sterile percarditis model. J. Cardiovasc Electrophysiol. 612-624, 1996.
214.
Gidh-Jain M, Huang B, Jain P, El-Sherif N: Differential expression of voltage-gated potassium channel
genes in left ventricular remodeled myocardium following experimental myocardial infarction.Cir. Res.
79: 669-675, 1996.
215.
Zhang Z H, Johnson J A, El-Sherif N, Mochy-Rosen D, Boutjdir M: C2 region-derived peptides of B
protein kinase C regulate cardiac calcium channels. Circ Res. 80: 750-9, 1997
216.
Yin h, El-Sherif N, Caref EB, Ndrepapa G, Levin R, Isber N, Stergiopolis K, Assadi MA, Gough WB,
Restivo M: Action of lidocaine on reentrant ventricular rhythms in the subacute myocardial infarction
period in dogs. Am J Physiol. 272: H299-H309, 1997.
217.
Boutjdir M, Chen L, Zhang Z H, Tseng C E, DiDonato F, Rashbaum W, Morris W, El-Sherif N, Buyon
JP: Arrhythmogenicity of IgG and anti-52KDSSA/Ro affinity purified antibodies from mothers of
children with congenital heart block. Circ Res 80:354-362, 1997.
218.
Estes NA 3rd, Michaud G, Zipes D, El-Sherif N, Venditti FJ, Rosenbaum DS, Albrecht P, Wang PJ,
Cohen RS: Electrial alternans during rest and exercise as predictors of vulnerability to ventricular
arrhythmias. Am J Cardiol, 80:1314-8, 1997.
219.
El-Sherif N, Chinushi M, Caref EB, Restivo M: Electrophysiological mechanism of the characteristic
electrocardiographic morphology of torsade de pointes tacharrhythmias in the long-QT syndrome: detailed
analysis of ventricular tridimensional activation patterns. Circulation 96: 4392-9, 1997.
220.
Turitto G, Abordo MG, Mandawat MK, Togay VS, El-Sherif N: Radiofrequency ablation for cardiac
arrhythmias causing postcardiac injury syndrome. Am J Cardiol, 81: 369-70, 1998.
23
221.
Turitto G, El-Sherif N: Risk stratification for recurrent tacharrhythmias in patients with paroxysmal atrial
fibrillation and flutter: role of signal averaged electrocardiogram and echocardiography. Pacing Clin for
Electrophysiol, 21: 197-201, 1998.
222.
Gidh-Jain M, Huang B, Jain P, Gick G, El-Sherif N: Alterations in cardiac gene expression during
ventricular remodeling following experimental myocardial infarction. J Mol Cell Cardiol, 30:627-37,
1998.
223.
Mandawat MK, Turitto G, El-Sherif N: Catheter entrapment in the mitral valve apparatus requiring
surgical removal: an unusual complication of radiofrequency ablation. Pacing Clin for Electrophysiol, 21:
772-3, 1998.
224.
Vazquez R, Caref EB, Torres F, Reina M, Huet J, Guerro JA, El-Sherif N: Comparison of the new
acceleration spectrum analysis with other time-and frequency-domain analyses of the signal-averaged
electrocardiogram. Eur Heart J,19: 628-37, 1998.
225.
Boutjdir M, Chen L, Zhang Z-H, Tseng C-E, El-Sherif N, Buyon JP: Serum and immunoglobulin G from
the mother of a child with congenital heart block induce conduction abnormalities and inhibit L-type
calcium channels in a rat heart model. Pediatr Res, 4: 11-9, 1998.
226.
Chinushi M, Restivo M, Caref EB, El-Sherif N: Electrphysiological basis of arrhythmogenicity of QT/T
alternans in the long-QT syndrome: tridimensional analysis of the kinetics of cardiac repolarization. Circ
Res, 83: 614-28, 1998.
227.
Vazquez R, Caref EB, Torres F, Reina M, Espina A, El-Sherif N: Improved diagnostic value of combined
time and frequency domain analysis of the signal-averaged electrogram after myocardial infarction. J Am
Coll Cardiol, 33: 385-94, 1999.
228.
El-Sherif N, Turitto G: The long QT syndrome and Torsade De Pointes. Pacing Clin Electrophysiol, 22:
91-110, 1999.
229.
Chen L, El-Sherif N, Boutjdir M: Unitary Current Analysis of L-type Ca2+ Channels in Human Fetal
Ventricular Myocytes. J. Cardiovasc. Electrophysiol, 10:560-568, 1999.
230.
Mazel JA, El-Sherif N, Bouyon, Boutjdir M: Conduction Abnormalities in a Murine Model for the
Clinical Syndrome of Congenital Heart Block. Circulation, 99: 1914-18, 1999.
231.
El-Sherif N, Caref EB, Chinushi M, Restivo M: Mechanism of arrhythmogenecity of the short-long
cardiac sequence that precedes ventricular tachyarrhythmias in the long QT syndrome. J Am Coll Cardiol,
33: 1415-23, 1999.
232.
Huang B, Wang S, Qin D, Bourjdir M, El-Sherif N: Diminished basal phosphorylation level of
phospholamban in the post-infarction remodeled rat ventricle. Role of -adrenergic pathway, GI protein,
Phosphodiesterase, and phosphatases. Circ Res 85:848-855, 1999.
233.
Qu Y, Ghatpande A, El-Sherif N, Boutjdir M: Gene expression of Naa/Ca2+ exchange during development
in human heart. Cardiovas Res 45: 866-873, 2000.
234.
Huang B, Qin D, Deng L, Boutjdir M, El-Sherif N: Reexpression of T-type Ca2+channel gene and current
in post-infarction remodeled rat left ventricle. Cardiovase Res 46:442-449, 2000.
24
235.
Vazquez R, Caref EB, Torres F, Reina M, Guerrero JA, El-Sherif N: Reproducibility of time-domain and
three different frequency-domain techniques for the analysis of the signal-averaged electrocardiogram. J
Electrocardiol 33:99-105, 2000.
236.
Huang B, Qin D, El-Sherif N: Early down-regulation of K+ channel genes and currents in the post
infarction heart. J Cardiovasc Electrophysiol 11:1252-1261, 2000.
237.
Gold MR, Bloomfield DM, Anderson KP, El-Sherif N, wilbur DJ, Groh WJ, Estes M, Kauffman ES,
Greenberg ML, Rosenbaum DS. A comparison of T-wave alternans, signal averaged electrocardiography,
and programmed ventricular stimulation for arrhythmia risk stratification. J Am Coll cardiol, 36:22482253, 2000
238.
Huang B, El-Sherif T, Gidh-Jain M, Qin D, El-Sherif N: Alterations of sodium channel dinetics and gene
expression in the postinfarction remodeled myocardium. J Cardiovasc Electrophysiol 12:218-225, 2001
, 2001.
239.
Chinushi M, Caref EB, Restivo M, Noll G. Aizawa Y, El-Sherif N: Cycle-length associated modulation of
the regional dispersion of ventricular repolarization in a canine model of long QT syndrome. Pace,
24:1247-1257, 2001.
240.
Qin D, huang B, Deng L, El-Adawi H, ganguly K, Sowers JR, El-Sherif N. Downregulation of K+
channel genes expression in tyoe I diabetic cardiomyopathy. Biochem Biophys Res comm 283:549553,2001.
241.
Turitto G, El-Attar G, Helal M, Pedalino R, El-Sherif N: Optimal heart rate cutoff criteria for
determination of exercise induced T-wave alternans. J. Nonivas Electrocardiol. 6(2:123-128,2001.
242.
Deng L, Huang B, Qin D, Ganguly K, El-Sherif N. Calcineurin inhibition ameliorates structural,
contractile, and electrophysiologic consequences of post-infarction remodeling. J Cardiovas Electrophys
2001; 12:1055-1061.
243.
Huang B, Qin D, El-Sherif N. Spatial alterations of Kv channels expressions and K+ currents in post-MI
remodeled rat heart. Cardiovas Res 2001; 52:246-254.
244.
Restivo M, Hegazy M, El-Hamami M, Yin H, Caref EB, Assadi MA, Brooks RR, El-Sherif N. Efficacy
of azimilide and dofetilide in the dog right atrial enlargement model of atrial flutter. J Cardiovasc
Electrophysiol 2001; 12:1018-1024.
245.
Kozhevnikov DO, Yamamoto K, Robotis D, El-Sherif N. Electrophysiological mechanism of enhanced
susceptibility of hypertrophied heart to acquired torsade de pointes arrhythmias. Tridimensional mapping
of activation and recovery patterns. Circulation 2002; 105:1128-1134.
246.
Castillo R, Pedalino RP, El-Sherif N, Turitto G, Efavirenz. Associated QT prolongation and torsade de
pointes arrhythmia. Ann Pharmacotherapy 2002; 36:1006-1008.
247.
Alakhras M, Baldari D, El-Sherif N, Turitto G. Location and clinical implications of high degree atrio
ventricular block during dipyridamole infusion. Ann Noninvas Electrocard 2002; 7:174-176.
248.
Turitto G, Mirandi AP, Pedalino R, Uretsky S, El-Sherif N. Short term reproducibility of T-wave
alternans measurement. J. Cardiovasc Electrophysiol 2002; 13: - (July 2002).
249.
El-Adawi H, Deng L, Tramontano A, Smith S, Mascareno E, Ganguly K, Castillo R, El-Sherif N. The
functional role of the JAK-STAT pathway in post-infarction remodeling. Cardiovas Res 2003;58:126-135.
25
250.
Chinushi M, Kozhevnikov D, Caref EB, Restivo M, El-Sherif N. Mechanism of discordant T-wave
alternans in the invivo heart. J Cardiovasc Electrophysiol 2003;14:632-638.
251.
Tramontano AF, Muniyapa R,Black AD, Blenda MC, Cohen I, Deng L, Sowers JR, Cutaia MV, El-Sherif
N. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent
pathway. Biochem biophys Res Comm 2003; 308:990-994.
252.
El-Sherif N, Turitto G. Risk stratification and management of sudden cardiac death: A new paradigm. J
Cardiovasc Electrophysiol 2003; 14:1113-1
253.
Restivo M, Caref EB, Kozhevnikov DO, El-Sherif N. Spatial dispersion of repolarization is a key factor in
the arrhythmogenicity of long QT syndrome. J Cardiovasc Electrophysiol. 2004; 15:323-331.
254.
Tramontano AF, O’Leary J, Black AD, Muniyappa R, Cutaia MV, El-Sherif N. Statin decreases
endothelial particle release from human coronary artery endothelial cells: implication for the Rho-kinase
pathway. Biochem Biophys Res Commun 2004;320:34
255.
Bub G, El-Sherif. Monolayer cell culture as model systems for studying paroxysmal atrial fibrillation. J
Electrocardiol 2004;37Suppl:44-46.
256.
Lakireddy V, Baweja P, Sayed A, Bub G, Boutjdir M, El-Sherif N. Contrasting effects of ischemia on the
kinetics of membrane voltage and intracellular calcium transient underlie electrical alternans. Am J
Physiol Heart Cir Physiol 2005; 288: H400-H407.
257.
Qu Y, Baroudi G, Yue Y, El-Sherif N, Boutjdir M. Localization and modulation of alpha1D (Cav1.3) Ltype Ca channel by protein kinase A. Am J Physiol Heart Cir Physiol 2005;288(5):H2123-H2130.
258.
Lakireddy V, Bub G, Baweja P, Syed A, Boutjdir M, El-Sherif N. The kinetics of spontaneous calcium
oscillations and arrhythmogenesis in the in vivo heart during ischemia/reperfusion. Heart Rhythm
2006;3:58-66.
259.
Turitto G, Haq S, Benson D, El-Sherif N. Torsade de pointes: an electrophysiological effect of cardiac
resynchronization? Pacing Clin Electrophysiol 2006;29(5):520-22.
260. Turitto G, El-Sherif N. Cardiac resynchronization therapy: a review of proarrhythmic and antiarrythmic
mechanisms. Pacing Clin Electrophysiol 2007; 30(1):115-122.
261.
Turitto G, Onura A, Saponiere C, El-Sherif N. Prolonged transient atrial electrical silence following
termination of atrial tachyarrhythmia. Pacing and Clinical Electrophysiology 2007; 30:1311-1315.
262. Caref BE, Boutjdir M, Himel, HD, El-Sherif N. Role of subendocardial Purkinje network in triggering
torsade de pointes arrhythmia in experimental long QT syndrome. Europace 2008;10(10):1218-1223.
263. Mancarella S, Yue Y, Karnabi E, El-Sherif N, Boutjdir M. Impaired Ca2+ homeostasis is associated with
atrial fibrillation in the alpha 1D L-tyope Ca2+ channel KO mouse. Am J Physiol Heart Circ Physiol.
2008;295(5):H2017-H2024.
26
264. Turitto G, Akhrass P, Leonardo M, Saponiere C, Sette A, El-Sherif N. Atrial flutter with spontaneous 1:1
atrioventricular conduction in adults: an uncommon but frequently missed cause for syncope/presyncope.
Pacing Clin Electrophysiol 2009;32(1):82-90.
265. Kozhevnikov D, Caref EB, El-Sherif N. Mechanisms of enhanced arrythmogenecity of regional ischemia in
the hypertrophied heart. Heart Rhythm 2009;6(4):522-527.
266. El-Sherif N, Pedalino R, Himel H 4th. Role of pharmacotherapy in cardiac ion channelopathies. Curr Vasc
Pharmacol 2009;7(3):358-366.
267. Fleischmann KE, Orav EJ, Lamas GA, Mangione CM, Schron EB, Lee KL, Goldman L; Most investigators.
Atrial fibrillation and quality of life after pacemaker implantation for sick sinus syndrome: data from the
Mode Selection Trial (MOST). Am Heart J2008;158(1):78-83.
268. Himel D IV, Bub G, Yuankun Y, El-Sherif N. Early voltage/calcium uncoupling predestinates the duration
of ventricular tachyarrhythmias during ischemia/reperfusion. Heart rhythm 2009; 6(9):1359-1365.
269. Deng L, Boutjdir M. Tramontano A, Pincus MR, El-Sherif N. A peptide from a ras effector-domain blocks
ras-dependent cardiac hypertophy in myocytes. Ann Clin&Lab Sci 2009;39:351-360.
270. El-Sherif N, Jalife J. Paroxysmal atrioventricular block: are phase 3 and phase 4 block mechanisms or
misnomers. Heart rhythm 2009;6(10):1514-1521.
271. Giada F, Biffi A, Cannon DS, Cappato A, Corrado D, Delise P, Drezner JA, El-Sherif N, Estes M 3rd,
Furlanello F, Heidbucher H, Inama G, Lindsay BD, Maron MS, Mont L, Olshansky B, Pelliccia A, Thiene
G, Viskin S, Zeppilli P, Natale A, Raviele A,. Sports and arrhythmias: A report of the International
Workshop Venice Arrhyuthmias 2009. Eur J Cardiovas Prev Rehabil 2010;17(5):607-12.
272. El-Sherif N, Khan A, Savarese J, Turiyyo G. Pathophysiology, risk stratification, and management of sudden
cardiac death in coronary artery disease. Cardiol J. 2010;17(1): 4-10.
273. Ameem A, Dharawat A, Khan A, El-Sherif N. The varied presentation of His bundle extrasystoles. The great
electrocardiographic masquerader. Pacing Clin Electrophysiol , 34(6):e56-9, 2010.
274. Khan A, Ameen A, Maraj I, Turitto G, El-Sherif N. A his bundle extrasystole can both induce and reverse
2:1 atrioventricular block. J Interv Card Electrophysiol 32(2):121-3, 2011.
275. Caref EB, Ndrepepa G, Turitto G, Restivo M, El-Sherif N. Improved activation time assignment of unipolar
electrograms from ischemic canine epicardium. Pacing Clin Electrophysiol, 34(9):1105-15, 20112011.
276. El-Sherif N, Turitto G. Electrolyte disorders and arrhythmogenesis. Cardiol J 18(3):233-45, 2011.
277. Verrier RL, Klingenheben T, Malik M, El-Sherif N, Exner DV, Honloser SH, Ikeda T, Martinez JP, Naryan
SM, Nieminen T, Rosenbaum DS. Microvolt T-wave alternans. Physiological basis, methods of measurement,
and clinical utility-consensus guideline by International Society of Holter and Noninvasive Electrocardiology. J
Am Coll Cardiol, 58(13):1309-24, 2011.
278. Verrier RL, Klingenheben T, Malik M, El-Sherif N, Exner DV, Honloser SH, Ikeda T, Martinez JP, Naryan
SM, Nieminen T, Rosenbaum DS. Microvolt T-wave alternans testing has a role in arrhythmia risk stratification.
J Am Coll Cardiol, 59(17):1572-3, 2012.
279. Himel HD, Bub G, Lakireddy P, El-Sherif N. Optical mapping of arrhythmias in the cardiomyocyte
monolayer. Heart Rhythm. 9:2077-82, 2012.
27
280. Restivo M, Kozhevnikov DO, Qu Y, Rosen D-M, El-Sherif N, Boutjdir M. Activation of ePKC reduces
perfusion arrhythmias and improve recovery from ischemia: optical mapping of activation patterns in the isolated
Guinea-pig heart. Biochem biophys Res Comm 426(2):237-41,2012.
281. Himel HD, Gary A, Noble PJ, Wadgoanker R, Savarese J, Liu N, Bub G, El-Sherif N. Electronic
suppression of early afterdepolarizations in the neonatal rat ventricular myocyte monolayer. J Physiol
591.21:5357-64, 2013.
28
N. EL-SHERIF, M.D.
BOOKS
1.
CARDIAC PACING. Editors, P. Samet and N. El-Sherif, 1980, Grune & Stratton.
2.
THE PATHOPHYSIOLOGY and PHARMACOTHERAPY of MYOCARDIAL INFARCTION. Editors,
N. El-Sherif, and C.V.R. Reddy, 1986. Academic Press.
3.
CARDIAC PACING AND ELECTROPHYSIOLOGY. Editors, N. El-Sherif and P. Samet, 1991, W.B.
Saunders.
4.
HIGH RESOLUTION ELECTROCARDIOGRAPHY. Editors, N. El-Sherif and G. Turitto, 1991. Futura
Publishing Co.
5.
HIGH RESOLUTION ELECTROCARDIOGRAPHY, 1994 Update. Editors, N. El-Sherif and G.Turitto,
Moduzzi Editore, Bologna, Italy, 1994.
6.
PRACTICAL TREATMENT OF CARDIAC ARRHYTHMIAS. Editors, N.El-Sherif and J. LeKieffre,
Futura Publishing Co. Armonk, NY 1997
7.
ATRIAL FLUTTER AND FIBRILLATION, FROM BASIC TO CLINICAL APPLICATIONS. Editors,
N. Saoudi, W. Schoels, and N. El-Sherif, Futura Publishing Co., Armonk, NY 1998.
29
N. El-Sherif, M.D.
BOOK CHAPTERS, REVIEW ARTICLES
1.
El-Sherif, N., Comparative study of orthogonal and scalar electrocardiography. M.D. Thesis . Faculty of
Medicine, Cairo University, 1965.
2.
Sorour, A.H., El-Sherif, N., Shahwan, L. The effect of heat on pulmonary circulation. Proceedings of the
Fifth International Congress of Cardiology, 1970, pp 132-150.
3.
Berbari, E.J., Lazzara, R., El-Sherif, N., Scherlag B.J.: Signal averaging applications in cardiac
electrophysiology. Proc. San Diego Biomedical Symposium, 1975, pp 395-402.
4.
Myerburg, R.J., El-Sherif, N.: Electrocardiographic diagnosis of sinus rhythm variations and sino-atrial
block.
In: Advances in Electrocardiography. R.C. Schlant and J.W. Hurst, Editors. Grune and
Stratton, 1976 pp 59-70.
5.
Scherlag, B.J., Hope, R.R., Williams, D.O., El-Sherif, N., Lazzara, R.: Mechanisms of ectopic rhythm
formation due to myocardial ischemic effects of heart rate and ventricular beats. IN: Workshop on the
specific conduction system of the heart. Editors, H. Wellens, K. Lie, R. Durrer, Amsterdam, 1976 pp 633649.
6.
El-Sherif, N.: Tachycardia and bradycardia dependent conduction disorders. In: "Self-Assessment in
Clinical Cardiology". Editor, M.S. Gordon, Year Book Medical Publishers, Inc., 1976, pp 100-103.
7.
El-Sherif, N., Scherlag, B.J., Lazzara, R.: Pathophysiology of second degree and paraoxysmal
atrioventricular block in acute myocardial infarction. IN: Pathophysiology and Therapeuctics of
Myocardial Ischemia. Editors, A.M. Lefler, G.J. Kelliher, M.S. Rovetto, Spectrum Publications, 1977,
pp 49-79.
8.
El-Sherif, N., Javier, R., Gann, F., Waxman, H., Samet, P.: Pacemaker electrocardiography.
In:
Cardiac Pacing. Editors, P. Samet and N. El-Sherif, Grune and Stratton, 1980, pp 149-206.
9.
El-Sherif, N.: Electrophysiologic basis of programmed electrical stimulation of the heart in the study and
treatment of ventricular tachycardia. In: Cardiac Pacing. Editors, P. Samet and N. El-Sherif, Grune and
Stratton, 1980, pp 295-316.
10.
El-Sherif, N., Gann, D., Samet, P.: Pathophysiology of atrioventricular and bundle branch blocks in acute
myocardial infarction. In: Cardiac Pacing. Editors, P. Samet and N. El-Sherif, Grune and Stratton, 1980,
pp 409-438.
11.
Gomes, J.A.C., El-Sherif, N.: His bundle recordings. Contributions to clinical electrophysiology. In:
Cardiac Pacing. Editors, P. Samet and N. El-Sherif, Grune and Stratton, 1980, pp 375-407.
12.
Gann, D., El-Sherif, N., Samet, P.: Indication for cardiac pacing. In: Cardiac Pacing.
and El-Sherif, Grune and Stratton, 1980, pp 207-228.
13.
Gann, D., El-Sherif, N., Samet, P.:
role of electrophysiologic studies.
Stratton, 1980, pp 505-528.
14.
El-Sherif, N: The ventricular premature complex. Mechanisms and Significance. In: Diagnosis and
Management of Difficult Arrhythmias. W.J. Mandel, Editor, J.B. Lippincott Co., pp 288-320, 1980.
Editors, P. Samet
Prognostic value of the HV interval in conduction disorders: The
In: Cardiac Pacing. Editors, P. Samet and N. El-Sherif, Grune and
30
15.
El-Sherif, N., Gomes, J.A.C., Kelen, G.J., Khan, R.G., Kang, P.S., Zeiler, R.H.: Electrophysiology of
reentrant ventricular arrhythmias in the late myocardial infarction period. In: Medical and Surgical
Management of Tachyarrhythmias. Editors, W. Bricks, F. Loogen, H.D. Schulte, and L.Seipel.
Springer-Verlag, 1980, pp 2-23.
16.
El-Sherif, N., Gomes, J.A.C., Kelen, G.J., Khan, R.G., Kang, P.S., Zeiler, R.H.: Electrophysiological,
Biochemical and pharmacological Aspects of Reentrant Ventricular Arrhythmias in the Late Myocardial
Infarction Period. In: Sudden Death.
Editors, H.E. Kulbertus, H.J.J. Wellens, 1980, pp 104-133.
17.
El-Sherif, N.: Arrhythmias in acute myocardial infarction. In: Harrison's Principles of Internal
Medicine - Patient Management Problems: Pre-Test Self Assessment and Review. McGraw-Hill
Book Co., 1980, pp 91-95.
18.
Gomes, J.A.C., El-Sherif, N.: Management of tachyarrhythmias in acute myocardial infarction. Practical
Cardiology 7:73-84, 1981.
19.
Gomes, J.A.C., El-Sherif, N.: Recognition of antiarrhythmic drug Toxicity in acute myocardial infarction.
Practical Cardiology Vol 9 (1) 61-71, 1983.
20.
El-Sherif, N.: Effects of reversible cooling on reentrant tachycardia in canine infarction.
the VII World Symposium on Cardiac Pacing. pp 173-181, 1983.
21.
Mehra, R. Restivo, M.S., El-Sherif, N.: Electromyographic noise reduction for high resolution
electrocardiography. IEEE Proceedings on Frontiers of Engineering and Computing in Health Care, 1983,
pp 248-253.
22.
Gomes, J.A.C., El-Sherif, N.: Atrioventricular block-mechanism, clinical presentation, and Therapy.
Med. Clin. North America, 68 (4):955, 1984.
23.
Hariman, R.J., El-Sherif, N.: Atrial tachycardia, clinical diagnosis and therapy. Practical Cardiology.
Arrhythmia Clinic 1/3:37:38, 1984.
24.
El-Sherif, N.: The low noise (high resolution) electrocardiogram. (Editorial) International J. Cardiol. 6,
1984, pp 185-188.
25.
El-Sherif, N.: The Figure of 8 model of reentrant excitation in the canine post-infarction heart. Cardiac
Electrophysiology and Arrhythmias, Eds. D. Zipes and J. Jalife, Grune and Stratton, 1985, pp 363-378.
26.
Craelius, W., Restivo, M., El-Sherif, N.: Computer stimulation of ventricular tachycardia. IEEE
Proceedings on Frontiers of Engineering and Computing in Health Care. 1985. Vol. 1:451-455.
27.
Craelius, W., Restivo, M., Henkin, R., Caref, E., El-Sherif, N.: High resolution ECG amplifier for signal
averaging. IEEE Proceedings on Frontiers of Engineering and Computing in Health Care. Vol II: 860-863,
1985.
28.
El-Sherif, N.: Electrophysiolgy of ventricular arrhythmias in myocardial infarction. In: Pathophysiology
and Pharmacotherapy of Myocardial Infarction. Eds. N. El-Sherif and C.V.R. Reddy, Academic Press, Inc.
1986, pp 187-240.
29.
Reddy, C.V.R., El-Sherif, N.: Pump failure and role of vasopressors in acute myocardial infarction. In:
Pathophysiology and Pharmacotherapy of Myocardial Infarction. Eds. N. El-Sherif and C.V.R. Reddy,
Academic Press, Inc. 1986, pp 85-117.
Proceedings of
31
30.
El-Sherif, N.: The ventricular premature complex: Mechanism and significance - An Update. In: Cardiac
Arrhythmias. Their Mechanisms, Diagnosis and Management. Ed. J. Mandel, J.B. Lippincott Co. 1987,
pp 288-319.
31.
Fontaine, J., Turitto, G., El-Sherif, N.: Prognostic siginificance of ambulatory electrocardiographic
recording, programmed electrical stimulation and signal averaged electrocardiogram in patients with
complex ventricular arrhythmias. J Electrophysiol, 1:204-216, 1987.
32.
Craelius, W., Restivo, M., El-Sherif, N.: Averaging of the ECG for late potentials: Possibilites and
limitations. Proc. 13th Ann Northeast; Bioengr Confr, pp 60-62, 1987.
33.
Evans GT Jr., Scheinman, MM., Zipes, DP., Benditt,D., Camm, AJ., El-Sherif, N., Fisher, J., Fontaine G.,
German L., Hartzler, G., Josephson, M., Morady, F., Ruskin, J.: Catheter ablation for control of cardiac
arrhythmias: A report of the percutaneous cardiac mapping and ablation registry. In: Nonpharmacolgical
Therapy of Tachyarrhythmias. G. Breithardt, M. Borgrafe, D.P. Zipes (Eds). Futura Publishing Co., 1987
pp. 243-255.
34.
El-Sherif, N.: Mechanisms of resetting, entrainment, acceleration or termination of reentrant ventricular
tachycardia by programmed electrical stimulation. In: Non-Pharmacolgic Therapy of Tachyarrhythmias.
Ed. Breithart, Borgrafe and Zipes, Futura Publishing Co., 1987, pp 325-344.
35.
El-Sherif, N., Turitto, G., Fontaine, J.M.: Risk stratification of patients with complex ventricular
arrhythmias. Value of ambulatory electrocardiographic recording, programmed electrical stimulation and
the signal averaged electrocardiogram. Herz . 13(3):204 - 214, 1988.
36.
Turitto, G., El-Sherif.: Role of the signal averaged electrocardiogram and electrophysiologic study in the
management of patients with non-sustained ventricular tachycardia. New Trends in Arrhythmias. 5:431 435, 1988.
37.
El-Sherif, N., Turitto, G., Fontaine, JM.: Risk stratification of patients with complex ventricular
arrhythmias. Value of ambulatory electrocardiographic recording, programmed electrical stimulation and
the signal averaged electrocardiogram. Emirates Medical J.6: 118 - 127, 1988.
38.
El-Sherif, N: Long QTU and Torsades de Pointes due to bradycardia- dependent early
afterdepolarizations. Arrhythmia Clinic. 5:32-41, 1988
39.
El-Sherif, N.: Reentry Revisited. Pace. 11:1358 - 68, 1988.
40.
El-Sherif, N., Gough, W.B., Restivo, M., Craelius, W., Henkin, R.: Electrophysiological basis of
ventricular late potentials. In: Progress in Clinical Pacing. M. Santini, M. Pistolese, A. Alliegro (Eds),
Excerpta Medica, 1988,pp 209-223.
41.
Turitto, G., Fontaine, J.M., Shanta N.V., Caref, E.B., Henkin, R., El-Sherif, N.: The signal averaged
electrocardiogram as a predictor of the results of programmed stimulation.
Cardiology Review Board.
6:46-53, 1989.
42.
El-Sherif, N., Restivo, M., Craelius, W., Henkin, R., Kelen, G., Fontaine, J., Ursell, S., Turitto, G.: High
resolution electrocardiography. Basic and Clinical aspects. In: Electrocardiography and Cardiac Drug
Therapy. V. Hombach, H.H. Hilger and H.L. Kennedy (Eds): Kluwer Academic, Publishers. 1989; pp.
172-203.
43.
El-Sherif, N.: Electrophysiologic mechanisms in Electrical therapy of ventricular tachycardia. In:
Electrical Therapy for Cardiac Arrhythmias. S. Sakensa and N. Goldschlager (Eds). W.B. Saunders & Co.
1990, pp 395-410.
32
44.
Ursell, S., El-Sherif, N.: Electrocardiography of single-chamber pacemakers. In: Electrical Therapy of
Cardiac Arrhythmias. S. Saksena and N. Goldschlager (Eds), W.B. Saunders & Co. 1990, pp 205-224.
45.
El-Sherif, N., Gough, W.B.: Bradycardia-dependent early afterdepolarizations and triggered activity. A
mechanism for the arrhythmogenic effect of some drugs. In: Clinical Aspects of Ventricular
Repolarization. G.S. Butrous. P.J. Schwartz (Eds), Ferrand Press. London 1990, pp 279-288.
46.
El-Sherif N, Craelius W, Boutjdir M, Gough WB: Early after- depolarizations and arrhythmogenesis. J
Cardiovasc Electrophysiology 1:145-160, 1990.
47.
El-Sherif N, Restivo M, Gough WB: Principles of reentry learned from ventricular tachycardia models.
In: Atrial arrhythmias. Current Concepts and Management. P. Touboul, A.L. Waldo (Eds). Mosby
Yearbook, 1990, pp. 93-111.
48.
El-Sherif, N., Restivo, M, Gough, W.B.: Reentrant ventricular rhythms in the three-to-five day old canine
post-infarction heart. In: Electrophysiology amd Pharmacology of the Heart. K.H. Dangman, D.S. Miura
(Eds). Marcel Dekker, Inc., New York, 1991, pp. 331-350.
49.
El-Sherif, N., Turitto, G.: Risk stratification for sudden death in patients with complex ventricular
arrhythmias. Value of Electrophysiologic testing and the signal-averaged electrocardiogram. In: The
Prevention of Sudden Death. J.B. Kostis, M. Sanders (Eds) Wiley-Liss, Inc., New York 1990, pp 109-138.
50.
El-Sherif N, Gough WB, Restivo M, Boutjdir M: Electrophysiology of ventricular arrhythmias in
myocardial ischemia and infarction. In: Cardiac Pacing and Electrophysiology. N. El-Sherif, P. Samet
(Eds) W.B. Saunders. 1990, pp. 18-56.
51.
Ursell S, Habbab M, El-Sherif N: Atrioventricular and intraventricular conduction disorders. Clinical
Aspects. In: Cardiac Pacing and Electrophysiology. N. El-Sherif, P. Samet (Eds) W.B. Saunders. 1990,
pp. 140-169.
52.
Turitto, G., El-Sherif, N.: Complex ventricular arrhythmias and nonsustained ventricular tachycardia:
Risk stratification and management. In: Cardiac Pacing and Electrophysiology. N. El-Sherif, P. Samet
(Eds) W.B. Saunders. 1990, pp. 217-232.
53.
El-Sherif N, Restivo M, Craelius W, Mehra R, Henkin R, Caref EB, Kelen G: The high resolution
electrocardiogram. Technical and basic aspects. In: Cardiac Pacing and Electrophysiology.
N. ElSherif, P. Samet (Eds) W.B. Saunders. 1990, pp. 349-371.
54.
Fontaine J, Ursell S, El-Sherif N: Electrocardiography of single chamber pacemakers. In: Cardiac
Pacing and Electrophysiology. N. El-Sherif, P. Samet (Eds) W.B. Saunders. 1990, pp. 568-598.
55.
Restivo M, Gough WB,El-Sherif N: Antitachycardia pacing; Electrophysiologic mechanisms. In:
Cardiac Pacing and Electrophysiology. N. El-Sherif, P. Samet (Eds) W.B. Saunders. 1990, pp. 685-705.
56.
El-Sherif N, Ibrahim BB: Significance of electrophysiologic study and the signal averaged
electrocardiogram for risk stratification in the post-infarction period. In: Progress in Clinical Pacing.
M. Santini, M, Pistolese, A. Alliegro (Eds) Excerpta Medica, 1990, pp 13-24.
57.
El-Sherif N, Gough WB, Restivo M, Craelius W, Henkin R, Caref EB:
ventricular late potentials. Pace 13:2140-2147, 1990.
58.
Turitto G, El-Sherif N: The signal averaged electrocardiogram and programmed stimulation in patients
with complex ventricular arrhythmias.
Pace 13:2156-2159, 1990.
Electrophysiological basis of
33
59.
El-Sherif N: Early afterdepolarizations and arrhythmogenesis. Experimental and Clinical Aspects. Arch
Mal Coeur Vass. 84:227-234, 1991.
60.
Craelius W, Restivo M, El-Sherif N: Techniques for processing of cardiac signals; Fiducial formula for
fidelity. In: High Resolution Electrocardiography.N. El-Sherif, G. Turitto (Eds). Futura Publ. Co.
1992,pp 21-49.
61.
Caref EB, El-Sherif N: Role of bandpass filters for time domain analysis of the signal averaged ECG. In:
High Resolution Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura Publ. Co. 1992, pp 67-103.
62.
Henkin R, Caref EB, Kelen G, El-Sherif N: Comparative analysis of commercial devices. In: High
Resolution Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura Publ. Co. 1992,pp 173-185.
63.
El-Sherif N, Mehra R: Beat-to-beat recordings of a high resolution ECG. Technical and clinical aspects.
In: High Resolution Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura Publ. Co. 1992,pp 189210.
64.
El-Sherif N, Restivo M, Gough WB, Caref EB, Craelius W: Electrophysiologic correlates of late
potentials. In: High Resolution Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura Publ. Co.
1992,pp 279-298.
65.
El-Sherif N, Bekheit S, Turitto G, Fontaine J, Ursell SN, Caref EB: Late potentials in the post-infarction
period. Role in risk stratification strategies. In: High Resolution Electrocardiography.
N. El-Sherif,
G. Turitto (Eds). Futura Publ. Co. 1992,pp 427-446.
66.
Turitto G, Caref EB, El-Sherif N: Late potentials and acute ischemic syndromes. In: High Resolution
Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura Publ. Co. 1992,pp 447-469.
67.
Turitto G,Fontaine J, Ursell S, Bekheit S, El-Sherif N: Late potentials in patients with non-sustained
ventricular tachycardia. In: High Resolution Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura
Publ. Co. 1992,pp 473-494.
68.
Fontaine JM, Turitto G, El-Sherif N: Bundle branch block and the signal averaged ECG. In: High
Resolution Electrocardiography. N. El-Sherif, G. Turitto (Eds). Futura Publ. Co. 1992,pp 533-567.
69.
Kelen G, Henkin R, Caref EB, Bloomfield D, El-Sherif N: Spectral turbulence analysis and inducibility
of ventricular tachycardia. In: High Resolution Electrocardiography.
N. El-Sherif, G. Turitto (Eds).
Futura Publ. Co. 1992,pp 655-681.
70.
El-Sherif N: Vetricular arrhythmias in subacute myocardial infarction. In: Cardiac Electrophysiology and
Arrhythmias. C. Fisch, B. Surawicz (Eds) Elsevier, North-Holland. 1991,pp 79-95.
71.
El-Sherif N: Electrophysiologic mechanisms of ventricular arrhythmias. In: Int J Card Imaging. 7: 141150,1991.
72.
Breithardt G, Cain ME, El-Sherif N, Flowers N, Hombach V, Janse M, Simson MB, Steinbeck G:
Standards for analysis of ventricular late potentials using high resolution or signal-averaged
electrocardiography. Circulation, J Am Coll Cardiol 17:999-1006,1991, Eur Heart J 12:473-480, 1991.
73.
Schoels W, El-Sherif N: Interaction of pacing interventions with ventricular and supraventricular
tachycardias. In: Interventional Electrophysiology. B Luderitz, S Saksena (Eds.), Futura Publishing Co.,
1991, pp 153-170.
34
74.
El-Sherif N: Experimental models of reentry, antiarrhythmic, and proarrhythmic actions of drugs.
Complexities galore! Circulation 84:1871-1875, 1991.
75.
El-Sherif N: Long QTU and torsade de pointes. Role of early afterdepolarizations. In: Current Practice of
Cardiology. A. Oto (Ed), Futura Media Service, Inc., 1991, pp. 341-356.75.
76.
El-Sherif N: Significance of the signal averaged electrocardiogram for risk startification in the
postinfarction period. In: Current Practice of Cardiology, A. Oto (Ed), Futura Media Service, Inc., 1991,
pp. 357-370.
77.
El-Sherif N, Turitto G: Complex Ventricular Arrhythmias. Their Mechanisms, Diagnosis and
Management. In: Cardiac Arrhythmias. W. Mandel (Ed), J.B. Lippincott Co., In press.
78.
Habbab M, El-Sherif N: Electrcardiographic changes and complicating arrhythmias in valvular heart
disease. In: Valvular Heart Disease. M Al- Zaibag and CMG Duran (Eds), Marcel Dekker, Inc. 1994,
pp 449-477.
79.
El-Sherif N: Early afterdepolarizations and arrhythmogenesis. Cardio. March 1992, pp 56-69.
80.
El-Sherif N: Electrophysiologic mechanisms of ventricular arrhythmias. In: Biomagnetism. Clinical
Aspects. M. Hoke, S.N. Erne, Y. C. Okada, and G. L. Romani (Eds) Excerpta Medica Amersterdas, 1992,
pp. 429-438.
81.
El-Sherif N: Early afterdepolarizations and arrhythmogenesis. New trends in arrhythmias. VIII No.
1/2:333-338, 1992.
82.
El-Sherif N, Turitto G: Risk stratification of patients with non-sustained ventricular tachycardia. In:
Progress in Clinical Pacing. M. Santini, M. Pistolese, A. Alliegro (Eds). Futura Publish Co. 1992, pp.333342.
83.
El-Sherif N: Clinical significance of polymorphic ventricular tachycardia induced by programmed
stimulation (Editorial). J Am Coll Cardiol. 21:99-101, 1993.
84.
El-Sherif N, Boutjdir M, Gough WB, Restivo M: Pro-arrhythmic consequences of pharmacologicallyinduced prolonged repolarization. Experimental considerations. In: Electropharmacologic Control of
Cardiac Arrhythmias: To delay conduction or to prolong refractoriness? Singh BN, Wellens HJJ,
Hiraoka M (Eds). Futura Publish Co.Inc., Mt. Kisco, NY 1993, pp 335-356.
85.
Schoels W, El-Sherif N: Mapping of atrial flutter in the sterile pericarditis model. In: Cardiac Mapping.
M. Shenasa, M. Borgreffe, G. Breithardt, (Eds), Futura Publish Co., Inc. Mount Kisco, NY 1993, pp. 281290.
86.
El-Sherif N, Gough W B, Restivo M: The figure eight model of reentrant excitation. In: Cardiac Mapping
M. Shenasa, M. Borgreffe, G. Breithardt, (Eds), Futura Publish Co., Inc. Mount Kisco, NY 1993, pp. 159182.
87.
El-Sherif N: The pro-arrhythmic mechanism of drugs that prolong repolarization. Role of early
afterdepolarizations. New Trends in Arrhythmias. 8(4):617-626, 1992.
88.
El-Sherif N: Electrophysiologic mechanisms of reentrant ventricular tachyarrhythmias. In: Signal
Averaged Electrocardiography. JAC Gomes (Ed). Kluwer Academic Publishers. pp. 29-46, 1993.
35
89.
Turitto G, Ahuja R, El-Sherif N: Role of the signal averaged ECG in patients without coronary artery
disease and nonsustained ventricular tachycardia. In: Signal Averaged Electrocardiography. JAC
Gomes (Ed). Kluwer Academic Publishers. pp 413-432,1993.
90.
El-Sherif N, Mehra R, Restivo M: Beat-to beat high-resolution electrocardiogram. Technical and clinical
aspects. Prog. Cardiovas. Dis. 35:407-415, 1993.
91.
El-Sherif N: Electrophysiologic basis of ventricular late potentials. Prog. Cardiovasc. Dis. 35:417-427,
1993.
92.
Turitto G, El-Sherif N: Potenziali tardivi ventricolari e tachicardia ventricolare non associata a
cardiopatia ischemica. Cardiostimolazione 1993:11:146-158.
93.
El-Sherif N, Boutjdir M: The autonomic nervous system and ventricular arrhythmias. New Trends in
Arrhythmias 9:169-175,1994.
94.
El-Sherif N, Jain P, Turitto G: Cardiac electrophysiology in the older population. Am J Geriatric
Cardiology. 3(3):55-62,1994.
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El-Sherif N: Optimizing the predictive value of the signal-averaged ECG for serious arrhythmic events in
the post-infarction period. In: Cardiac Pacing and Electrophysiology, AE Aubert, H Ector & R
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El-Sherif N, Jain P: Management of atrial fibrillation. J Saudi Heart Association. 7:5-11, 1995.
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Armonk, New York 1995, pp 3-16.
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El-Sherif N: The signal averaged EKG Complex: Technical and Clinical Aspects. In: Progress in Clinical
Pacing 1994, M. Santini (Ed): Futura Publ. Co, Inc., Armonk, New York 1995, pp 17-28.
102.
El-Sherif N, Turitto G, Jain P: Advances in the anatomy and physiology of AV nodal and AV pathways.
In: Interventional Electrophysiology, B. Luderitz and S. Saksena (Eds). Futura Publ. Co, Inc., 1995, pp.323.
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El-Sherif N: Arrhythmogenic substrate of ventricular tachyarrhythmias. Implications for management.
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69-87.
104.
El-Sherif N: High resolution electrocardiography. In: Non invasive Electrocardiology, A.J. Moss and S.
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El-Sherif N: High resolution (signal-averaged) electrocardiography. In: Japanese Heart, 1995. In press.
36
106.
El-Sherif N: T wave altenans. A marker of vulnerability to ventricular tachyarrhythmias. In: Cardiac
Arrhythmias 1995. (Ed.) A. Raviele. Springer 1996: 12-16.
107.
El-Sherif N, Turitto G, Caref EB: Nonsustained ventricular tachycardia in ischemic heart disease: risk
stratification and management strategies. In: Practical Management of Cardiac Arrhythmias, N. ElSherif and J. Lekieffre (eds), Futura Publishing Co, Inc, Armonk, NY 1997, pp. 41-55.
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Turitto G, El-Sherif N. Blocchiatrio-ventricolari e blocchi di branca. In: Manuale Pratico di
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Turitto G, El-Sherif N. Tachicardia e fibrillazione ventricolare. In: Manuale Pratico di Cardiologia.
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Turitto G, El-Sherif N. Fibrillazione e flutter atriale. In: Manuale Pratico di Cardiologia. A.Blasio (Ed),
Casa Editrice Scientifica Internazionale, Rome 1998, pp. 224-228.
111.
El. Sherif N, Turitto G: The need for powerfull risk stratification of sudden cardiac death in the era of
prophylactic ICD. In: Progress in Clinical Pacing 1998, M. Santini (Ed), Futura Medica Services, Inc.
Armonk, NY 1998, pp. 263-271.
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El-Sherif N: Mechanism of ventricular arrhythmias in ischemic heart disease. In: Cardiac Arrhythmias,
Pacing & Electrophysiology. The Expert View. P.E. Vardas (Ed), Kluwer Academic Pubs.,
Dordrecht/Boston/London, 1998, pp. 61-69.
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El-Sherif N: Experimental basis of drug action in atrial flutter and atrial fibrillation. In: Atrial flutter
and fibrillation. From Basic to Clinical Applications. N. Saoudi, W. Schoels, N. El-Sherif (Eds). Futura
Publ. Co., Inc. Armonk, NY 1998, pp. 193-213
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El-Sherif N: Advances in Cardiac Arrhythmias. From molecular biology to clinical management. G.
Italiano di Cardiologia 28 (Suppl I)270-273, 1998.
115.
Turitto G, Cebeci B, Clark LT, El-Sherif N: Non-invasive testing in athletes: Signal averaged ECG and
ambulatory recordings. In: R.A. Williams (ed): The Athlete and Heart Disease. Lippincott Williams &
Wilkins, Philadelphia, PA, 1999, pp. 183-195.
116.
El-Sherif N, Kozhevnikov DO, Turitto G: The contribution of disorders of cardiac repolarization to
arrhythmogenesis in the long QT syndrome. G Ital Cardiol 29; Suppl 5:157-163, 1999.
117.
El-Sherif N, Turitto G: T-wave alternans: Clinical and experimental observations. G Ital Cardiol 29;
Suppl 5:199-202, 1999.
118.
Turitto G, Ekl-Sherif N: The high resolution electrocardiogram: basic and clinical aspects. G Ital
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119.
El-Sherif N, Turitto G: In search of the optimal algorithm for risk stratification of sudden cardiac death
in the era of prophylactic ICD. G Ital Cardiol 29; Suppl 5:316-321.
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El-Sherif N, Huang B, Qin D: Cellular 2 molecular bases of arrhythmias in the postinfarction
remodeled ventricular myocardium. In: Cardiac Electrophysiology from cell to bedside. DP Zipes, J
Jalife (Eds), WB Saunders & Co., 1999, pp. 405-414.
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El-Sherif N, Turitto G: Torsades de Pointes. In: Cardiac Electrophysiology from cell to bedside. DP
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El-Sherif N, Caref EB: Disorders of cardiac repolarizaiton and arrhythmogenesis. In: Monaphasic
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El-Sherif N, Turitto G, Kozhevnikov DO, Restivo M: The electrophysiological mechanism of Torsade
de Pointes in the long QT syndrome. In: Dispersion of ventricular repolarization: State of the Art, SB
Olsson, S Yuan, JP Amlie (Eds), Futura Publ Co. Inc. Armonk, NY, 2000 pp. 175-198, 2000.
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Turitto G, El-Sherif N: Electrophysiologic Mechanisms of Polymorphic ventricular
tachycardia/Torsade de Pointes in the Presence of Normal or Long QT. In: Cardiac Arrhythmias 1999,
A. Raviele (Ed), Springer-Verlag Italia, Milan 2000, pp. 276-284.
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El-Sherif N. Turitto G: Risk Stratification for serious Arrhythmic Events in Post-Infarction patients. In:
Cardiac Arrhythmias 1999, A. Raviele (Ed), Springer-Verlag Italia, Milan 2000, pp. 351-360.
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Turitto G. El-Sherif N: Late Potential Recording and the Risk of Ventricular Arrhythmias. In: Cardiac
Arrhythmia: How to Improve the Reality in the Third Millenium? #. Adornato (Ed) Edizioni Luigi
Pozzi s.r.l. Rome 2000, pp. 141-150.
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El-Sherif N. Turitto G: Post-Infarction Remodeling. A target for Therapeutic Intervention. In: Cardiac
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Pozzi s.r.l. Rome 2000, pp. 398-409.
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Soliman SA, Robotis DA, El-Sherif N: Cost-effective Management of Ventricular Tachyarrhythmias in
the Post-Myocardial Infarction Patient. In: Progress in Clinical Pacing 2000, M. Santini (Ed),
Tipolitografia Fernando Begliomini, CEPI s.r.l. Rome 2000, pp. 244-260.
129.
El-Sherif N, Turitto G: In Search Of The Optimal Algorithm for Risk Stratification of Sudden Cardiac
Death in the Era of Prophylactic ICD. Mediterranean J Pacing & Electrophysiol 1:65-70, 1999.
130.
El-Sherif N, Turitto G. Atrial fibrillation. An overview of management strategies. In: trento Crdiologia
2001, M.Disertori (ed). Casa Editrice Scientifica Internazionale, Rome 2001, pp51-54.
131.
Turitto G, el-Sherif N.QRS averaging. In: Noninvasive Electrocardiology in Clinical Practice,
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El-Sherif N, Turitto G, Kozhevnikov D, Restivo M. The electrophysiological mechanism of torsade de
pointes in the long QT syndrome. In: S.B. Olson, J. P. amlie, S. Yuan (eds): Dispersion of Ventricular
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El-Sherif N. Polymorphic ventricular tachycardia and torsade de pointes. Beyond etymolgy. J
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El-Sherif N. Mechanism of ventricular arrhythmias in the long QT syndrome: On hermeneutics. J
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135.
El-Sherif N, Turitto G, Pedalino RP, Robotis D, Togay V, Soliman S. T-wave alternans, a powerful
index for malignant ventricular arrhythmias. Fact or fiction? In: Cardiac Arrhythmias (2001), A
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Turitto G, Pedalino RP, Togay V, Soliman S, El-Sherif N. Left ventricular hypertrophy. Neglected
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137.
El-Sherif N, Turitto G, Pedalino R, Robotis D. T-wave alternans and arrhythmia risk stratification. J
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138.
Robotis D, Turitto G, El-Sherif N. Arrhythmias and electrolyte disorders. In: Electrophysiological
disorders of the heart, S Saksena, AJ Camm (eds), Harcourt Health Sciences Publishers, Philadelphia,
PA, 2002. In press.
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El-Sherif N, Caref EB, Restivo M. The figure-of-eight model of reentrant ventricular arrhythmias. In:
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Schoels W, El-Sherif N. Mapping of atrial flutter In: Cardiac Mapping, M Shenasa, M Borggrefe, G
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141.
El-Sherif N, Turitto G. Disorders of cardiac repolarization and arrhythmogenesis. In: Cardiac
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142.
Antzelevitch C, El-Sherif N, Rosenbaum D, Vos M. Cellular mechanisms underlying the long QT
syndrome. J Cardiovasc Electrophysiol. 2003;14:114-115.
143.
El-Sherif N, Turitto G. Anatomical substrate and electrophysiological mechanisms of malignant
ventricular arrhythmias. In: Non pharmacological treatment of sudden death. M Santini, Ed. Ariana
Editrice, Casalecchio, Italy 2003, pp. 41-72.
144.
Turitto G, El-Sherif N. What is the prognostic value of non-sustained ventricular tachycardia inpatients without severely depressed ejection fraction after myocardial infarction? In: Cardiac
Arrhythmias 2003, M Raviele (Ed), Springer Verlag, Milan Italy, 2003, pp 120-126.
145.
El-Sherif N, Turitto G. Drug-induced torsade de pointes. Role of genetic factors. In: Cardiac
Arrhythmias 2003, M Raviele (Ed) Springer Verlag, 2003, pp. 145-152.
146.
El-Sherif N. Management of sudden cardiac death in the new millennium. In: Cardiac arrhythmias. E
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*El-Sherif N. Electrical and structural remodeling in atrial fibrillation. Clinical and therapeutic
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Turitto G, El-Sherif N. Identification of patients with heart failure at high arrhythmic risk. In: Cardiac
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39
151.
El-Sherif N, Baroudi G. Atrial fibrillation. Molecular Biology has yet to impact management (
Editorial). J Cardiovasc Electrophysiol 2004;15:224-225.
152.
El-Sherif N, Turitto G. Sudden cardiac death: The new paradigm. J Saudi Heart Assocation
2005;17:85-92.
153.
El-Sherif N, Turitto G. Electrophysiologic effects of Carvedilol. Is carvedilol an antiarrhythmic agent?
Pacing Clin Electrophysiol 2005;28(9):985-90
154.
El-Sherif N, Turitto G. Proarrhythmic versus antiarrhythmic mechanisms of cardiac resynchronization
therapy. Folia Cardiol 2006;13:517-521.
155.
El-Sherif N. The challenge of management of electrical storm and out-of-hospital cardiac arrest.
Cardiology Journal 2007;144: 326-328.
156. El-Sherif N. The challenge of cardiac tridimensional mapping. HRJ 2007; 4(11):1437-1440.
157. Giada F, Barold SS, Biff A, De Piccoli B, Delise P, El-Sherif N, Gold MR, Gorenek B, Grubbi B, Inama
G, Kautzner J, Molina L, Olshansky B, Pelliccia A, Thiene G, Wellens H, Wolpert C, Zeppilli P, Raviele
A, Heidbuchel H. Sport and Arrhythmias: Summary of International Symposium. Eur J Cardiovasc Prev
Rehabil 2007;14:707-714.
158. El-Sherif N, Bub G, Lakireddy V. The kinetics of intracellular calcium and arrhythmogenesis in
ischemia/reperfusion. In: Cardiac Mapping, Third Edition, Eds: Shenasa M, Hindricks G, Borggrefe M,
Breithart G, Blackwell Publishing Ltd, Oxford 2008
159. Turitto G, Abdulla R, Bense D, El-Sherif N. Signal Averaged Electrocardiogram. In; Electrical Diseases
of the Heart. Genetics, Mechanisms, Treatmeny, Prevention; I.Gussac, C Antzelvich, Eds; SpringerVerlag, London 2008; 353-364.
160. H. D. Himel IV, J. Savarese, V. Lakireddy, and N. El-Sherif. Cardiac optical mapping in biomedicar research
Application of Photodiodes,” In:Integrated Circuits, Photodiodes, and Organic Field Effect Transistors, Nova
Publishers, Hauppauge, NY2009
160. El-Sherif N. Pathophysiology of ventriculae arrhythmias in myocardial infarction and sudden cardiac death.
In: Coronary Care Manual, Editor, PL Thompson, Elsevier Australia, 2011,pp 79-88.
161. Himel DH, Bub G, El-Sherif N. Ortical mapping of arrhythmias in cardiomyocyte monolayer culture. In:
Optical Mapping, 4th edition. Eds: M Shenasa, G Hindricks, M Borggrefe, G Breihart. Blackwell Publishing, pp
98-107, 2012.
162.El-Sherif N, Turitto G, boutjdir M, Pilai S, Otte B, Pedalino R. The electrophysiological basis of ECG
characteristics of Tosade de Pointes in the long QT syndrome. In: Cardiac Electrophysiology Clinics, Eds, M
Shenasa, E Gerstenfeld. 2014, Elsevier .
40
STRACTS
1.
El-Sherif, N., Scherlag, B.J., Samet, P. Analysis of second degree A-V block following acute myocardial
ischemia of the canine His-Purkinje system. Clin. res. 21:417, In press.
2.
El-Sherif, N., Scherlag, B.J., Lazzara, R., Schoenfeld, C., Samet, P. Tachycardia and bradycardia
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3.
Scherlag, B.J. El-Sherif, N., Lazzara, R. Experimental production of Mobitz type II A-V block in the His,
right and left bundle of the dog heart, Clin. Res. 21:448, 1973.
4.
Scherlag, B.J., El-Sherif, N., Samet, P. Pathophysiology of Intra-His bundle lesions due to myocardial
ischemia. Clin. Res. 21:448, 1973.
5.
Scherlag, B.J., El-Sherif, N., Abelleira, J.L. Technique for stable recordings from specific PurkinjeMuscle junctions in vivo. Fed. Proc. 32:418, 1973.
6.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Pathophysiology of intra-His bundle block following acute
myocardial ischemia in dogs. Circulation 48: (Suppl IV) 20, 1973.
7.
Rodriguez, J., El-Sherif, N. Scherlag, B.J. Lazzara, N. Delta waves and bilateral bundle branch block due
to dissociation in the pathologic His bundle. Circulation 48: (Suppl IV) 208, 1973.
8.
Scherlag, B.J., El-Sherif, N., Lazzara, R. Latent His bundle lesions: Limitations of the standard recording
techniques. Circulation 48: (Suppl IV) 102, 1973.
9.
Scherlag, B.J., El-Sherif, N., Rodriguez, J., Lazzara, R. A model for the study of Mobitz Type II and
paroxysmal A-V block. Circulation 48: (Suppl IV) 215, 1973.
10.
Lazzara, R., El-Sherif, N., Scherlag, B.J. The cellular basis of ischemic heart block and bundle branch
block. Circulation 48: (Suppl IV) 189, 1973.
11.
El-Sherif, N., Scherlag, B.J., Lazzara, R., Hope, R., Williams, D.O. The pathophysiology of bilateral
bundle branch block following acute myocardial ischemia in dogs. Clin. Res. 22:5A, 1974.
12.
Hope, R., Berbari, E.J., El-Sherif, N., Williams, D.O., Lazzara, R., Scherlag, B.J. The His bundle
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13.
Williams, D.O., Hope, R., El-Sherif, N., Lazzara, R., Scherlag, B.J., Characteristics of the malignant
ventricular premature beat. Clin. Res. 22:14A, 1974.
14.
Scherlag, B.J., El-Sherif, N, Lazzara, R. Bundle branch block due to His bundle lesions. Amer. J. Cardiol.
33:169, 1974.
15.
Lazzara, R, Scherlag, B.J., El-Sherif, N. Trans-membrane potentials in the His bundle after coronary
occlusion. Amer. J. Cardiol. 33:150, 1974.
16.
El-Sherif, N., Scherlag, B.J., Lazzara, R., Samet, P. The evolution of second degree block in the canine
proximal His-Purkinje system. Amer. J. Cardiol. 33:135, 1974.
17.
Scherlag, B.J., Lazzara, R., El-Sherif, N., Samet, P. Mechanisms of Wenckebach and Mobitz Type II
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41
18.
El-Sherif, N., Samad,A., Mascarenhas, E., Schoenfeld, C., Samet, P. Acute myocardial infarction in the
elderly. Influence of the coronary care unit on mortality. Clin. Res. 22:273A, 1974.
19.
El-Sherif, N. Supraventricular parasystolic rhythms. Clin. Res. 22:273A, 1974.
20.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Pathophysiology of second degree atrio-ventricular block.
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21.
El-Sherif, N., Scherlag, B.J., Lazzara, R. The pathophysiology of paroxysmal atrio-ventricular block after
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22.
Berbari, E.J., Scherlag, B.J., Williams, D.O., El-Sherif, N. Extracardiac recordings from the His-Purkinje
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23.
Hope, R.R., Scherlag, B.J., Williams, D.O., El-Sherif, N., Lazzara, R. The dual effect of non-vagal
induced bradycardia in acute myocardial ischemia. Circulation 50: (Suppl III) 99, 1974.
24.
Scherlag, B.J., Lazzara, R., El-Sherif, N. Simplified in vitro preparation from normal and abnormal dog
hearts. Circulation 50: (Suppl III) 203, 1974.
25.
Williams, D.O., Scherlag, B.J., Hope, R.R., El-Sherif, N., Lazzara, R. Pathophysiology of malignant
ventricular arrhythmias during acute myocardial ischemia. Circulation 50: Suppl III) 211, 1974.
26.
El-Sherif, N., Scherlag, B.J., Lazzara, R. The effect of combined ligation of the anterior septal artery and
the A-V nodal artery on the canine A-V conduction system. Circulation 50 (Suppl III) 171, 1974.
27.
El-Sherif, N., Samet, P. Multiform ventricular ectopic rhythm. Possible evidence for multiple parasystolic
activity. Circulation 50: (Suppl III) 223, 1974.
28.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Differential effects of atrial and ventricular pacing on the
induction of paraxysmal atrioventricular block in the canine ischemic His-Purkinje system. Clin. Res.
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29.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Electrode catheter recordings during malignant ventricular
arrhythmia following experimental acute myocardial ischemia. Evidence for reentry due to conduction
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30.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Experimental production of "Mobitz Type II" and paroxysmal
block in the A-V node. Clinic. Res. 23:181A, 1975.
31.
Lazzara, R., El-Sherif, N., Vallone, T., Scherlag, B.J. Conduction in depressed cardiac muscle. Circulation
51 #4 (Suppl II) 816, 1975.
32.
Lazzara, R., El-Sherif, N., Befeler, B., Scherlag, B.J. Lidocaine action on depressed cardiac cells.
Circulation 52 #4 (Suppl II) 331, 1975.
33.
Embi, A., Aranda, J., Scherlag, B.J., Befeler, B., El-Sherif, N., Lazzara, R. Induction of mitral valve
prolapse in the dog with one and two vessel stenosis. Circulation 52: (Suppl II) 178, 1975.
34.
El-Sherif, N., Myerburg, R.J. Befeler, B., Aranda, J., Castellanos, A., Lazzara, R. Electrocardiographic
characteristics of primary ventricular fibrillation. Value of the R-on-T phenomenon. Circulation 51 #4:
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42
35.
Befeler, B., Aranda, J.M., Wells, D.E., Machado, H., El-Sherif, N., Lazzara,R. Coronary artery aneurysms
in a population with ischemic heart disease. Circulation 51 #4 (Suppl II): 623, 1975.
36.
Scherlag, B.J., Vallone, T., El-Sherif, N., Lazzara, R. Functional tests of the bifascicular theory of the
canine left bundle branch. Circulation 51 #4 (Suppl II): 940, 1976.
37.
Befeler, B., Aranda, J.M., El-Sherif, N., Lazzara, R. Coronary artery dilatations. Their influence on left
ventricular function and prognosis. Amer. J. Cardiol. 37:120, 1976.
38.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Bradycardia-dependent conduction disorders. A clinical and
experimental correlation. Amer J Cardiol. 37:134, 1976.
39.
Berbari, E.J., Scherlag, B.J., El-Sherif, N., Befeler, B., Aranda, J.M., Lazzara, R. The His-Purkinje
electrogram in man. An initial assesment of its uses and limitations. Clin. Res. 24:420A, 1976.
40.
El-Sherif, N., Scherlag, B.J., Lazzara, R., Electrophysiological common denominator of paroxymal A-V
block. Clin. Res. 24 #3:471A, 1976.
41.
El-Sherif, N., Scherlag, B.J., Lazzara, R. Normalization of bundle branch block patterns by distal His
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42.
Berbari, E,J., Scherlag, B.J., El-Sherif, N., Lazzara, R. In vivo recordings from the area of the A-V node
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43.
Hope, R.R., Scherlag, B.J., El-Sherif, N., Lazzara, R. The Ashman phenomenon as a basis of malignant
ventricular arrhythmias during myocardial ischemia. Fed. Proc. 35:222, 1976.
44.
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45.
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46.
El-Sherif, N., Scherlag, B.J., Lazzara, R.,Hope, R.R. Critical analysis of ventricular reentry in the late
myocardial infarction period. Amer. J. Cardiol. 39#2, 1977.
47.
Scherlag, B.J., El-Sherif, N., Hope, R.R., Lazzara, R. Induction and release of complete block of sinus and
A-V nodal automaticity by D-600 and atrial pacing. Clin. Res. 25 #3:252A, 1977.
48.
Lazzara, R., El-Sherif, N. Effect of verapamil and D-600 on reentrant ventricular arrhythmias in the late
myocardial period. Cicrculation 56:III-128, 1977.
49.
El-Sherif, N.,Myorga-Cortes, A., Myerburg, R., Lazzara, R. Accelerated ventricular rhythms in acute
myocardial infarction and differential effect of lidocaine. Circulation 56:III-66, 1977.
50.
El-Sherif, N., Aranda, S., Befeler, B., Lazzara, R. Pseudo-Mobitz II A-V block. A variant of atypical
Wenckebach periodicity. Circulation 56:III-155, 1977.
51.
El-Sherif, N., Lazzara, R. Effect of neural impulses on ischemic reentrant ventricular arrhythmias.
Circulation 56:III-81, 1977.
52.
El-Sherif, N., Lazzara, R. Effect of lidocaine on acutely ischemic canine proximal His Purkinje system.
Circulation 56:III-159, 1977.
43
53.
El-Sherif, N., Lazzara, R. Effect of practalol on reentrant ventricular arrhythmias in the late myocardial
infarction period. The Physiologist 20 #4:25, 1977.
54.
El-Sherif, N., Aranda, J. Befeler, B., Lazzara, R. Variants of atypical Wenckebach periodicity. Chest
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55.
El-Sherif, N., Lazzara, R. Reappraisal of the mechanism of action of antiarrhythmic drugs on ischemic
reentrant ventricular arrhythmias. Am. J. Cardiol. 41:417, 1978.
56.
Smith, R.A., El-Sherif, N., Evans, K. Epicardial mapping of ventricular reentrant pathways in the late
myocardial infarction. Am. J. Cardiol. 41:427, 1978.
57.
El-Sherif, N., Lazzara, R. Mechanism of action of Ca blockers and role of the slow response in ischemiarelated reetrant ventricular arrhythmias. Circulation 58:II-66, 1978.
58.
Sung, R.J., Myerburg, R.J., El-Sherif, N., McAllister, R.G., Elser, B., Castellanos, A. Termination of
supraventricular tachycardia by verapamil in man: Correlation of plasma drug levels with Intracardiac
electrophysiologic studies. Circulation 58:II-177, 1978.
59.
El-Sherif, N., Gann, D., Sung, R.J. Initiation of ventricular fibrillation by supraventricular beats in patients
with acute myocardial infarction. Circulation 58:II-195, 1978.
60.
Rozanski, J.J., El-Sherif, N., Kleinfeld, M., Lazzara, R., Myerburg, R.J. ST segment alternans and
ventricular arrhythmias in Prinzmetal's angina. Circulation 58II-239, 1978.
61.
El-Sherif, N. Electrophysiologic basis of procainamide therapeutic and toxic effects on ischemia-related
reentrant ventricular arrhythmias. Am. J. Cardiol. 43:429, 1979.
62.
El-Sherif, N., Gomes, J.A.C., Kelen, G. Khan, R. Differential effect of isoprenaline in ventricular
parasytolic rhythm. Circulation 60:II-187, 1979.
63.
Rozanski, J.J., Myerburg, R.J., Castellanos, A., El-Sherif, N., Kleinfeld, M. T-G Segment (Baseline)
Alternans: A new ECG phenomen in Prinzmetal angina accompanying ST segment Alternans. Circulation
60:II-190, 1979.
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Gomes, J.A.C., Kang, P.S., Matheson, M., Kelen, G., El-Sherif, N. The repetitive ventricular response in
man: A prospective study of its incidence, inducibility, reproducibility and significance. Clinical Research
28, II-174A, 1980.
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Kang, P.S., Gomes, J., Kelen, G., Khan, R., El-Sherif, N. Simultaneous antegrade slow-fast AV nodal
pathway conduction following procainamide. Clinical Research 28, II-185A, 1980.
66.
Essesse, I., Gopalaswamy. C. El-Sherif, N. Cardiac Arrhythmias associated with doxorubicin
hydrochloride. Circulation 62(Suppl III)-182, 1980.
67.
El-Sherif, N., Zeiler, R., Gough, W. Effects of Catecholamines, Verapamil and tetrodotoxin on triggered
automaticity in canine ischemic Purkinje fibers. Circulation 62 (suppl III) - 281, 1980.
68.
Zeiler, R.H., Gough, W.B., Sung, R, El-Sherif, N. Electrophysiologic effects of propafenone on canine
ischemic cardiac cells. Am J Cardiology 47:483, 1981.
69.
El-Sherif, N., Gough, W.B., Zeiler, R.H., Mehra, R. Epicardial mapping of triggered automaticity in
canine ischemic Purkinje fibers. Am J Cardiology 47:489, 1981.
44
70.
El-Sherif, N., Wengerten, K., Kelen, G., Fine, E., Maayan, M. Correlation of left ventricular ejection
fraction by angiography. M-mode echocardiography and radionuclide imagening in clinical practice.
Proceeding of First International Symposium on Nuclear Cardiology. Tel Aviv, Israel, 1981, 205.
71.
Reddy, C.V.R., Gould, L., Khan, R., Singh, B.K., Zan, B., El-Sherif, N., VonBevern, J., Tomajko, D.
Reversed pulsus paradoxus. A new clinical observation. Chest 80:376, 1981.
72.
Kang, P., Gomes, J.A.C., Reddy, C.V.R., El-Sherif, N. Improved techniques of recording human sinus
node electrogram. Circulation 64:IV-67, 1981.
73.
Mehra, R., Zeiler, R.H., Gough, W.B., El-Sherif, N. Mechanism of repetitive ventricular responses
(RVRs): Reentry and dynamicity of arc of functional conduction block. Circulation 64:IV-172, 1981.
74.
El-Sherif, N., Gough, W.B., Zeiler, R.H., Mehra, R. Different mechanism for spontaneous and induced
ventricular rhtyhms in 24-hour-old myocardial infarction in the dog. Circulation 64:IV-218, 1981.
75.
Mehra, R., Kelen, G., El-Sherif, N. Non-invasive beat to beat recording of diastolic and His-Purkije
potentials in man. Circulation 64:I-239, 1981.
76.
Gough, W.B., Zeiler, R.H., El-Sherif, N., The antiarrhythmic action of nifedipine on triggered activity in
one-day-old ischemic endocardium. Circulation 64:IV-274, 1981.
77.
Gomes, J.A.C., Kang, P., Behl, A., Lyons, J., El-Sherif, N. Intravenous amiodarone. A potent and
effective drug for atrioventricular nodal reentrant paroxysmal tachycardia. Circulation 64:IV-317, 1981.
78.
Zeiler, R.H., Strand, F.L., El-Sherif, N. Canine left atrial tissue specifically binds adrenocortricotropic
hormone. Am J Cardiol 49:1037, 1981.
79.
Gough, W.B., Zeiler, R.H., El-Sherif, N., Effect of calcium and calcium antagonists on triggered activity
in one-day-old canine ischemic endocardium. Am J Cardiol 49:914, 1982.
80.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.H. Mechanism of reentrant rhythm induced by bursts of
rapid ventricular stimulation in the ischemic canine heart. Am J Cardiol 49:934, 1982.
81.
Hariman, R.J., Zeiler, R.H., Gough, W.B.,El-Sherif, N. The effect of ouabain on triggered activity in oneday-old canine infarction. Circulation 66:II-77, 1982.
82.
Zeiler, R.H., Gough, W.B., El-Sherif, N. Role of Ca2+ and Na+ on afterdepolarizations in canine
ischemic Purkinje fibers. Circulation 66:II-78, 1982.
83.
Gough, W.B., Zeiler, R.H., El-Sherif, N. Basis for reduced transmembrane potentials associated with
triggered activity in ischemic subendocardial Purkinje fibers. Circulation 66:II-156, 1982.
84.
El-Sherif, N., Gough, W.B., Zeiler, R.H., Mehra, R. Ventricular rhythms in one-day-old canine infarction
are due to triggered activity. Circulation 66:II-357, 1982.
85.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.H. Termination of reentrant circuits in canine infarction
by cryothermal techniques. Circulation 66:II-358, 1982.
86.
El-Sherif, N. Appraisal of a low noise electrocardiographic system for the diagnosis of cardiac
arrhythmias. Proceedings of IX World Congress of Cardiology, Moscow, 1982, 255.
45
87.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R. Ventricular activation patterns of pleomorphic
ventricular tachycardias that terminate spontaneously or degenerate into ventricular fibrillation. J Am Coll
Cardiol 2:621, 1983.
88.
Gomes, J.A.C., Chowdhry, I., Hariman, R.J., El-Sherif, N. New application of direct sinus node recording
in man: Assessment of sinus node recovery time. J Am Collo Cardiol 2:635, 1983.
89.
Gough, W.B., Zeiler, R.H., El-Sherif, N. Effects of diltiazem on triggered activity in one-day-old
ischemic endocardium of the dog. J Am Coll Cardiol 2:692, 1983.
90.
El-Sherif, N., Mehra, R., Gomes, J.A.C., Hariman, R. A low noise filtered electrocardiogram in the
diagnosis of complex cardiac arrhythmias. J Am Coll Cardiol (2) 705, 1983.
91.
Hariman, R.J., Gough, W.B.,Gomes, J.A.C., El-Sherif, N. Recording of diastolic slope in a canine model
of automatic and unifocal ventricular tachycardia. J Am Coll Cardiol (2):731, 1983.
92.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R. Effects of reversible cooling on reentrant tachycardias in
canine infarction. PACE 6 (3-II): 5, 1983.
93.
Gomes, J.A.C., Chowdry, I., Hariman, R., El-Sherif, N. New method of assessing sinus node recovery
time in man. PACE 6 (3-II): 118, 1983.
94.
Mehra, R., Hoover, E.L., Alma, C., El-Sherif, N. Spectral analysis of noninvasively recorded unipolar
ventricular and electromyographic potentials. PACE 6 (3-II): 54, 1983.
95.
Mehra, Hoover, E.L., Alma, C., El-Sherif, N. Noninvasive clinical
pacemaker sensing. PACE 6 (3-II): 113, 1983.
96.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.: Effects of reversible cooling on reentrant tachycardias
in canine infarction. Physiologist 26:A91, 1983.
97.
Mehra, R., Restivo, M., El-Sherif, N. Electrographic noise reduction for high resoltion
electrocardiography. IEEE Transactions of Biomedical Engineering Vol BVE-30#8:516, 1983.
98.
Mehra, R., Landman, D., Fried, P., El-Sherif, N. New Electrode for Recording Low Level Surface
Electrocardiographic Potentials. Proceeding of AAMI, 18th Annual Meeting 1983, p 83.
99.
Gough, W.B., Zeiler, R.H., El-Sherif, N. Effects of caffeine on triggered activity in one-day-old ischemic
endocardium of the dog. Circulation 68 (4): III-20, 1983.
100.
Reddy, C.V.R., Khan, R.G., Feit, A., Chowdry, I.H., El-Sherif, N. Effects of cigarette smoking on
coronary hemodynamics in coronary artery disease. Circulation 68 (4): III-165, 1983.
101.
Gomes, J.A.C., Mehra, R., Hariman, R., Barreca, P., El-Sherif, N. A prospective study of the high
frequency-components of the terminal portion of the QRS in acute myocardial infarction. Circulation 68
(4): III-172, 1983.
102.
Mehra, R., Gough, W.B., Zeiler, R., El-Sherif, N. Dual ventricular stimulation for prevention of reentrant
ventricular arrhythmias. J Am Coll Cardiol 3 (2):472, 1984.
103.
El-Sherif, N., Gough, W.B., Mehra, R., Zeiler, R.H., Restivo, M. The effect of differential shortening of
refractoriness in successive short cardiac cycles on the initiation and termination of reentry in the ischemic
canine heart. J Amer Coll Cardiol 3 (2):477, 1984.
measurement of paramters affecting
46
104.
Gough, W.B., Zeiler, R.H., El-Sherif, N. Dependence of triggered activity on diastolic potentials in oneday-old ischemic Purkinje fibers. J Amer Coll Cardiol 3 (2):477, 1984.
105.
Hariman, R.J., Holtzman, R., Gough, W.B., Mehra, R., Gomes, J.A.C., El-Sherif, N. In vivo
demonstration of delayed afterdepolrization as a cause of ventricular rhythms in one day old infarction. J
Amer Coll Cardiol 3(2):478, 1984.
106.
Hariman, R.J., Mehra, R., Gough, W.B., Holtzman, R., Gomes, J.A.C.,El-Sherif, N. Localization of the
sinus node: Comparison of cryothermal techniques with electrical mapping. J Amer Coll Cardiol 3
(2):495, 1984.
107.
Pasquariello, J.L., Hariman, R.J., Gomes, J.A.C., Barreca, P., El-Sherif, N. Autonomic depedence of
ventriculo-atrial conduction. J Amer Coll Cardiol 3 (2):517, 1984.
108.
Mehra, R., Gough, W.B., Zeiler, R., El-Sherif, N. Mechanisms of lidocaine action on reentrant ventricular
rhythms in the canine iscemic heart. J Amer Coll Cardiol 3 (2):542, 1984.
109.
El-Sherif, N., Mehra, R., Gough, W.B., Zeiler, R.H., Burst pacing versus multiple premature stimulation
in the induction of reentry. J Amer coll Cardiol 3 (2):587, 1984.
110.
Gomes, J.A.C., Hariman, R., El-Sherif, N., Lyons, J., Barreca, P. A prospective study of programmed
cardiac stimulation in patients with high grade ectopy. Electrophysiologic findings and prognosis for
survival. J Amer Coll Cardiol 3 (20:610, 1984.
111.
Reddy, C.V.R., Khan, R., Feit, A., El-Sherif, N. Effects of renografin on hemodynamics and resting
pulmonary gas exchange. Clinical Research 32 (2):199A, 1984.
112.
Khan, R.G., Reddy, C.V.R., Lorenz, J., El-Sherif, N. Spontaneous global myocardial ischemia during
angina - a marker of left main cornary artery stenosis. Clinical Research 32 (2):179A, 1984.
113.
Restivo, M.A., Li, J., Welkowitz, W., El-Sherif, N. Extracellular potential fields at sites of conduction
block. ACEMB, 1984, p.
114.
El-Sherif, N., Gough, W.B., Hariman, R., Zeiler, R.H., Restivo, M., Kowtha, V.: Mechanisms of
termination or acceleration of reentrant tachycardia by burst pacing. Circulation 70:II-91, 1984.
115.
Zeiler, R.H., Tobiasz, C.,Henkin, R., Gough, W.B., El-Sherif, N,: The effects of ischemia on intracellular
potassium activity and membrane potential in canine epicardial tissue. Circulation 70:II-225, 1984.
116.
El-Sherif, N., Gough, W.B., Hariman, R., Zeiler, R., Restivo, M., Kowtha, V.: Role of site of stimulation
for termination of reentrant ventricular tachycardia. Circulation 70:II-346, 1984.
117.
El-Sherif, N., Gough, W.B., Zeiler, R.H., Craelius, W., Restivo, M. Role of nonuniform refractory
distribution versus anisotrpoic anatomic properties in the initiation of reentrant excitation in the canine
post infarction heart. J Amer Coll Cardiol 5 (2):390, 1985.
118.
Restivo, M., Gough, W.B., Kowtha, V., El-Sherif, N. Mechanism by which dual paing prevents reentrant
ventricular arrhythmias. J Amer Coll Cardiol 5 (2):394, 1985.
119.
Hariman, R.J., Holtzman, R., Restivo, M., El-Sherif, N. Accuracy of pace mapping for localization of
ventricular ectopic focus. Evaluation by electrical and cryothermal mapping. J Amer Coll Cardiol 5
(2):411, 1985.
47
120.
Holtzman, R., Hariman, R.J., El-Sherif, N. Electrograms from the sinus node pacemaker recorded with a
suction electrode. Comparison with unipolar electrogram. J Amer Coll Cardiol 5 (2):467, 1985.
121.
Shanta N., Krasnow, N., El-Sherif, N.: Comparative role of sympathetic and parasympathetic system on
ventricular vulnerability to fibrillation. Clinical Research 33 (2): 227A, 1985.
122.
El-Sherif, Gough, W.B., Restivo, M., Kowtha, V. The mechanism by which abrupt changes in cycle
length facilitates the induction of reentrant rhythms. Circulation 72:III-279, 1985.
123.
Restivo, M., El-Sherif, N., Kelen, G.J., Henkin, R., Craelius, W., Gough, W.B. Correlation of late
potentials on the body surface and ventricular activation maps of reentrant circuits in the post infarction
dog heart. Circulation 72:III-3, 1985.
124.
Gough, W.B., Dayi, H., El-Sherif, N., Differential sensitivity of ischemic endocardium to clofilium
produces arrhythmias. Circulation 72:III-224, 1985.
125.
El-Sherif, N., Gough, W.B., Restivo, M. The mechanism for "Entrainment" and termination of reentrant
ventricular tachycardia by overdrive pacing. J Amer coll Cardiol. 7 (2):40, 1986.
126.
Restivo, M., Henkin, R., Craelius, W., Gough, W.B., El-Sherif, N. Are regions of delayed activation
during basic rhythm the responsible arrhythmogenic substrate for reentry? J Amer Coll Cardiol. 7 (2):85,
1986.
127.
Craelius, W., Chen, V., Zeiler, R.H., El-Sherif, N. In vivo recording of early afterdepolarizations
preceding Torsades de Pointes. J Amer Coll Cardiol. 7 (2):124, 1986.
128.
Kelen, G.J., Henkin, R., Restivo, M., Zeiler, R.H., Caref, E.B., El-Sherif, N. Signal averaging of high gain
Holter EKG recordings - validation of a new technique for detection of after-potentials. J Amer Coll
Cardiol. 7 (2): 104, 1986.
129.
Gough, W.B., Restivo, M., Kowtha, V,J., Assadi, M.A., El-Sherif, N. the dependence of reentry on the
site of stimulation in the ischemic canine ventricle. J Amer Coll Cardiol. 7 (2):166, 1986.
130.
Turitto, G., El-Sherif, N., Ursell, S., Stavens, C., Fontaine, J., Kelen, G., Caref, B., Henkin, R.
Comparison of programmed electrical stimulation and the signal averaged electrocardiogram in patients
with non-sustained ventricular tachycardia. Clinical Research 34 (2):349A, 1986.
131.
Clark, L.T., Crandall, D.L., Goldstein, B.M., Cervoni, P., El-Sherif, N. Effects of ethanol on blood
pressure, cardiac output and vascular resistances in wistar rats. Clinical Research 34 (2):476A, 1986.
132.
El-Sherif, N. Gough, W.B., Restivo, M. Mechanisms of "Entrainment" acceleration or termination of
reentrant ventricular tachycardia by programmed electrical stimulation. PACE 9(2):281, 1986.
133.
Craelius, W., Chen, V., El-Sherif, N. An improved floating microelectrode technique for recording
transmembrane potentials in vivo. PACE 9(2): 297, 1986.
134.
Fontaine, J.M., Zeiler, R.H., Henkin, R., El-Sherif, N. Simultaneous monophasic action potential
recording and regional endocardial refractory period determination using a new dual purpose contact
electrode catheter. PACE 9(2):278, 1986.
135.
Feit, A., Cohen, M., Holtzman, R., Dimino, L., El-Sherif,N. Comparative effects of Labetalol and
prazosin during exercise in hypertensive patients. Chest 89 (6) Suppl 494S, 1986.
48
136.
Sedlis, S.P., Sequeira, J.H., El-Sherif, N.: Uptake of lysophosphatides by cardiac myocytes. The
Physiologist 29(4):167, 1986.
137.
Clark, L.T., Crandall, D.L., Goldstein, B.M., Cervoni, P., El-Sherif, N.,: Hemodynamic mechanisms of
ethanol induced hypertension in the Wistar rat. Circulation 74 (Supp II):425, 1986.
138.
Gough, W.B., El-Sherif, N.: The differential response of ischemic endocardium to type III
antiarrhythmics: Early afterdepolarizations. Circulation 74:II-253, 1986.
139.
Turitto, G., Macina, G., Caref, E., Mittleman, R., Henkin, R., El-Sherif, N.:Lack of correlation between
Holter recording and signal averaged electrocardiogram in the post-infarction period. Circulation 74 (Supp
II): 402, 1986.
140.
Henkin, R., Kelen, G.J., El-Sherif, N.: Correlation between late potentials and frequency (FFT) analysis of
signal averaged ECG's - Importance of analyzed segment duration. Circulation 74 (Supp II):181, 1986.
141.
Turitto, G., Fontaine, J., Macina, G., Caref, E., Ursell, S., Stavens, C., El-Sherif, N.: Signal averaged ECG
predicts the inducibility of sustained ventricular tachycardia in patients with spontaneous nonsustained
tachycardia. J Am Coll Cardiol 7(2):151A, 1987.
142.
Restivo, M, Gough, W.B., El-Sherif, N.: Correlation of abrupt changes in refractoriness and functional
conduction block by high resolution electrode recordings in the post infarcted canine heart. J Amer Coll
Cardiol 9:91A, 1987.
143.
El-Sherif, N., Gough, W.B., Restivo, M.: Recovery of ischemic epicardium correlated with normalization
of refractoriness and failure to induce reentry in canine post-infarction heart. J Amer Coll Cardiol
9:253A, 1987.
144.
Zeiler, R.H., Sequeria, J.M., Henkin, R., Sedlis, S.P., El-Sherif, N.: Lysophosphatidyl choline: Putative
agent for maintained triggered activity in ischemic cardiac Purkinje fibers. J Amer Coll Cardiol
9(2):252A, 1987.
145.
Clark, L.T., Maw, M., Feldman, J., Niarchos, A., El-Sherif, N.: Predictor of mortality from acute
myocardial infarction in patients with low socioeconomic status. Clin. Res. 35:268A, 1987
146.
Clark, L.T., E.L., Cradndall, D.L., Cervoni, P., Haynes, S., El-Sherif, N.,: Atrial natiuretic peptide and
prostaglandin responses to alchol induced hypertension. Clin Res 35:440A, 1987.
147.
Turitto, G., Caref, E., Fontaine, J., Henkin, R., Ursell, S., El-Sherif, N.: Can the outcome of programmed
stimulation in patients with non-sustained ventricular tachycardia be predicted by non-invasive data?
Clinical Res. 35 (2):330A, 1987.
148.
El-Sherif, N.: High resolution electrocardiography. Basic and clinical aspects. Proceedings of the Fourth
International Symposium on Non-Invasive Cardiovascular Diagnosis and Therapy. Cologne, germany,
May 1987.
149.
Kelen, G.J., Henkin, R., Howard, M., Ferraro, C., El-Sherif, N,: Serial signal averages from Holter tapes
may reveal intermittent or changing late potentials. PACE 10:450:1987.
150.
Fontaine, J., Henkin, R, Howard, M., Turitto, G., Ursell, S., El-Sherif, N.: new signal averaging criteria
for determining the presence of late potentials in patients with left bundle branch block. PACE 10:451,
1987.
49
151.
Turitto, G., Fontaine, J., Ursell, S., Caref, El-Sherif, N.: Preditors of sustained ventricular tachyarrhythmia
inducibility in patients with spontaneous non-sustained ventricular tachycardia. PACE 10:448, 1987.
152.
Fontaine, J., Henkin, R., Howard, M., Turitto, G., Ursell, S., El-Sherif, N.: Establishing criteria for the
presence of late potentials in patients with left bundle branch block. PACE 10:675, 1987.
153.
Assadi, M., El-Sherif, N., Restivo, M., Gough, W.B., Wu, K.M., Williams, C., Prolonged sinus activation
time as a marker for sustained ventricular tachycardia. Proceedings of the International Symposium on
Cardiovascular Medicine and Surgery, Beijing, China, June 1987,p.62
154.
Assadi, M., El-Sherif, N., Clark, L. Wu, K.M.: Double blind comparison of the effect of captopril and
enalapril on the serum uric acid in mild to moderate hypertension. Chest 92(2):1405, 1987.
155.
Turitto, G., Fontaine, J., Caref, E., Benhuri, M., Howard, M., Ibrahim, B., El-Sherif, N.: Low risk of
sudden cardiac death in patients with non-sustained ventricular tachycardia and normal signal averaged
electrocardiogram. Circulation 76:IV-32, 1987.
156.
Restivo, M., Gough, W.B., Wu, K.M., El-Sherif, N.: Effect of anistropy and refractoriness in a functional
model of reentry. Circulation 76:IV-113, 1987.
157.
Restivo, M., Gough, W.B., Wu, K.M., Williams, C., El-Sherif, N.: Role of abrupt changes in
refractoriness and fiber orientation in the formation of functional conduction block. Circulation 76:IV241, 1987.
158.
Sedlis, S.P., Sequeria, J.M., Craelius, W., Henkin, R., Ahumada, G.G., El-Sherif, N.: Sustained
impairment in contractility of cardiac myocytes after accumulation of lysophosphatidyl choline.
Circulation 76:IV-332, 1987.
159.
El-Sherif, N., Zeiler, R., Craelius, W., Henkin, R., Gough, W.: Bradycardia-dependent QTU prolongation
and Torsades de Pointes due to early depolarizations. Circulation 76:IV-429, 1987.
160.
Craelius, W., Chen V KH., El-Sherif, N.: Sodium current modifications by anthopleurin-A and their role
in early afterdepolarizations. J Am Coll Cardiol II(2):253A, 1988.
161.
El-Sherif, N., Zeiler, R H., Craelius W., Gough, W.B., Henkin, R.: 2:1 block of an early
afterdepolarization as a mechanism for TU alternans. J Amer Coll Cardiol II(2): 254A, 1988.
162.
Assadi, M., El-Sherif, N., Gough, W.B.: Differential prolongation of ventricular refractoriness with time
in the post-infarction canine heart. Clinical Research, 36:259A, 1988.
163.
Bekheit,S., McDonald, N., Jain, A., Assadi, M., Stofchek, D., El-Sherif, N.: Assessment of mitral valve
function by Doppler echocardiography post myocardial infarction. Chest Vol. 94, No. 1, 58S, 1988.
164.
Fontaine, J., Klonis, D., Perri, C., El-Sherif, N.: Differential effects of rate responsive pacing in patients
with normal and ischemic heart disease. Pace 11 (6): 850, 1988.
165.
El-Sherif, N., Boutjdir, Henkin, R.: Role of purkinje and muscle fibers in a new model of Torsades de
Pointes due to early afterdepolarizations. Circulation 78 (4) II-158, 1988.
166.
Craelius, W., El-Sherif, N., Adler S., Kurtz, I., Golchin, K., Palant, C.: Stretch-activated ion channels in
mesangial cells. Circulation 78(4) II-233, 1988.
50
167.
Ursell, S., Bekheit, S., Ibrahim, B., Turitto, G., Fontaine, J., Henkin, R., Lannon, M. Caref, E., El-Sherif,
N.: The predictive accuracy of the signal averaged ECG in the post-infarction patient depends on the time
of recording. Circulation 78 (4)II-302, 1988.
168.
Boutjdir, M., Gough, WB., El-Sherif,N.: Effects of low and high concentration of caffeine in normal and
one day old ischemic endocardium of the dog. Circulation 78 (4) II-460, 1988.
169.
Turitto, G., Fontaine, J., Caref, E., Bekheit, S., El-Sherif, N.: Role of programmed stimulation and the
signal averaged ECG in the management of patients with organic heart disease and nonsustained
ventricular tachycardia. Circulation 78 (4) II-628, 1988.
170.
Craelius W., El-Sherif, N., Kurtz J, Palant C: Ionic currrents induced by stretch in cultured mesangial
cells. American Journal of Nephrology. In press.
171.
Caref EB, Turitto G, El-Sherif N: Enhancing prediction of induced ventricular tachycardia in patients with
non-sustained runs by the signal averaged electrocardiogram. J Am Coll Cardiol 13(2):34A, 1989.
172.
El-Sherif N, Restivo M, Williams C, Henkin R, Gough WB: Sustained reentrant activation orients around
arcs of abrupt functional conduction block in the canine post infarction heart. J Am Coll Cardiol
13(2):128A, 1989.
173.
Bekheit S, Restivo M, Henkin R, Boutjdir M, Gooyandeh K, Jean-Bart R, Williams C, Gough WB, ElSherif N: Effects of Glyburide on ischemia-induced changes in extracellular potassium and local
myocardial activation: A novel antiarrhythmic mechanism. J Am Coll Cardiol 13(2):142A, 1989.
174.
Amitzur G, Gough WB, El-Sherif N: Electrophysiologic effects of a chemical defibrillatory
agent:Dibenzepin. J Am Coll Cardiol 13(2):250A, 1989.
175.
Henkin R, Kelen G, Lannon M, El-Sherif N: Late potential analysis from three channel holter tapes; a
comparison with real-time recordings. Pace 12(1):690, 1989.
176.
Schoels W, Gough WB, Zaim B, El-Sherif N: Circus movement atrial flutter in the canine sterile
pericarditis model. Epicardial activation during initiation and termination of single loop reentry in vivo.
Circulation (Supp II): II-94, 1989.
177.
Boutjdir M, Gough WB, El-Sherif N: xi-adrenoreceptor modudlation of delayed afterdepolarizations and
triggered activity. Circulation (Supp II):II-201, 1989.
178.
Fontaine JM, Ursell S, Henkin R, Garcia L, Perri C, El-Sherif N: Assessment of differences in signalaveraged electrocardiogram parameters in patients with right and left bundle branch block. J Amer Coll
Cardiol 15 (Supp A): 100A, 1990.
179.
Habbab M, Reddy CVR, El-Sherif N: TU alternans, long QTU and Torsade de Pointes. Clinical and
experimental observations. J Amer Coll Cardiol 15 (Supp A):112A, 1990.
180.
Schoels W, Restivo M, El-Sherif N: Epicardial activation during entrainment and termination of singleloop reentry in vivo. J Amer Coll Cardiol 15 (Suppl A):123A, 1990.
181.
Craelius W, Restivo M, El-Sherif N: Slowly-inactivating sodium current as a source of early
afterdepolarizations in isolated ventricular myocytes. J Amer Coll Cardiol 15 (Suppl A):144A, 1990.
182.
Habbab M, Ursell S, Fontaine JM, Bekheit SS, El-Sherif N: Burst pacing versus programmed premature
stimulation for the initiation of reentrant ventricular tachycardia. Recordings from the slow zone of
reentry. J Amer Coll Cardiol 15 (Suppl A):253A, 1990.
51
183.
Restivo M, Kowtha V, Boutjdir M, Craelius W, El-Sherif N: Mechanism of earlyafterdepolarization
formation by delayed sodium inactivation. J Mol Cell Cardiol 27(Suppl I):S-13, 1990.
184.
Schoels W, Gough WB, El-Sherif N: Circus movement atrial flutter in the canine sterile pericarditis
model: Differential effects of procainamide on the components of the reentry pathway. PACE 13:513,
1990.
185.
Boutjdir M, Assadi M, Amitzur G, Torre P, Gough WB, El-Sherif N: Effects of cocaine on sustained
rhythmic activity in ischemic Purkinje fibers one day post infarction. PACE:13:521, 1990.
186.
Ibrahim BB, Caref EB, Kelen GJ, El-Sherif N: Spectral turbulence analysis versus late potentials analysis
of the signal averaged ECG in anterior versus inferior wall myocardial infaraction. Circulation (Suppl
III), III-355, 1990.
187.
Turitto G, Caref EB, El-Sherif N: Does transient myocardial ischemia create a substrate for late
potentials? Circulation (Suppl III) III-355, 1990.
188.
El-Sherif N, Gough WB, Restivo M: Short memory of ischemic myocardium. The mechanism by which
a short-long-short cardiac sequence facilitates induction of reentry. Circulation (Suppl III) III-452, 1990.
189.
Schoels W, Gough WB, Yang H, El-Sherif N: The slow zone in circus movement atrial flutter: Primary
target for antiarrhythmic drug action? Circulation (Suppl III) III-644, 1990.
190.
Schoels W, Yang H, Gough WB, El-Sherif N: Modulation of reentrant activation by structural
complexities of the right atrium. Circulation (Suppl III) III-648, 1990.
191.
Kelen GJ, Henkin R, Caref EB, Starr AM, Bloomfield D, El-Sherif N: Spectral turbulence analysis of the
high resolution ECG: A new concept and technique with higher predictive accuracy for inducible
sustained monmorphic ventricular tachycardia than detection of late potentials. Circulation (Suppl III) III740, 1990.
192.
Assadi MA, Bekheit S, DeSoto F, Farschian A, El-Sherif N: Eosinophilic syndrome mimicking
myocardial infarction. Clin Res 38(2):496A, 1990
193.
Butrous GS, Gough WB, Restivo M, Yang H, El-Sherif N: Adrenergic modulation of reentrant ventricular
arrhythmias in canine subacute myocardial infarction. European Heart J 12:42, 1991.
194.
Schoels W, Gough WB, El-Sherif N: A unified functional/anatomical substrate for circus movement atrial
flutter. Europen Heart J 12:368, 1991.
195.
El-Sherif N, Fozzard HA, Hanck DA: Voltage and dose-dependent modulation of cardiac sodium channel
by the sea anemone toxin ATXII. Circulation 84(Suppl) II-173, 1991.
196.
Gough WB, Restivo M, Yang H, El-Sherif N: The slow zone in circus movement atrial flutter: the
critical epicardial substrate. Circulation 84(Suppl) II-503, 1991.
197.
Schoels W, Brachmann J, El-Sherif N: Circus movement atrial flutter in the sterile pericarditis model:
correlation of surface ECG and activation map. Circulation 84(Suppl) II-504, 1991.
198.
Bekheit S, Isber N, Hani H, Boutjdir M, Butrous G, Gough WB, El-Sherif N: Protective
electrophysiological effects of glucose-insulin during acute ischemia. Circulation 84(Suppl) II-550, 1991.
52
199.
Boutjdir M, Restivo M, Wei Y, El-Sherif N: Sea anemone toxin induces early afterdepolarizations in
cardiac myocytes. Biophysical J. A303, 1992.
200.
El-Sherif N: Afterdepolarizations and triggered arrhythmias. J Moll Cell Cardiol 24(Suppl I) : 521, 1992.
201.
El-Sherif N: Ventricular tachycardia in coronary artery disease. Eur J Cardiac Pacing and
Electrophysiology 2: 2(Suppl A), A 129, 1992.
202.
Schoels W, El-Sherif N, Brachman J, Kubler W: Circus movement atrial flutter in the sterile pericarditis
model. location of reentrant circuits in relation to surface ECG characteristics. Eur J Cardiac Pacing and
Electrophysiology 2: (Suppl A). A 139, 1992.
203.
El-Sherif N: High resolution electrocariography. Technical and clinical status report. Eur J Cardiac
Pacing and Electrophysiology 2: 2(Suppl A), A 155, 1992.
204.
Turitto G, El-Sherif N: The signal averaged ECG and ventricular tachycardia. Eru J Cardiac Pacing and
Electrophysiology 2: 2(Suppl A), A158, 1992.
205.
Yang W, Gough WB, Schoels W, El-Sherif N, Restivo M: Natural anatomical obstacles and anisotropy
modulate functional conduction block during atrial flutter. Am Coll Cardiol 19:186A, 1992.
206.
Das C, Bekheit S, Turitto G, Caref EB, El-Sherif N: Significance of ejection fraction versus
noninducibility in nonsustained ventricular tachycardia and coronary artery disease. Circulation 86(4)I394, 1992.
207.
El-Sherif N, Denes P, Katz R, Capone R, Wyse G, Carlson M, Reynolds-Haertle R: Defining the best
prediction criteria of time-domain signal averaged electrocardiogram for serious arrhythmic events in the
post-infarction period. Circulation 86(4)I-525, 1992.
208.
Ahuja R, Ibrahim B, Caref EB, El-Sherif N: Combined time-and frequency-domain analysis of the
signal-averaged electrocardiogram improves its predictive accuracy in post-infarction patient. Circulation
(4) I-526, 1992.
209.
Isber N, Restivo M, Yang H, Caref EB, Gough WB, El-Sherif N: Activation patterns during termination
of clockwise and counterclockwise circus movement atrial flutter by cryothermal technique in dogs with
sterile pericarditis. J Am Coll Cardiol 21(Suppl A): 183A, 1993.
210.
Boutjdir M, Restivo M, Wei Y, El-Sherif N: Early afterdepolarizations formatioN: Correlation between
phase plane trajectory, action potential, and membrane currents in cardiac myocytes. J Am Coll Cardiol
21(Suppl A) 248A, 1993.
211.
Denes P, El-Sherif N, Katz R, Capone R, Wyse R, Reynolds-Haertle R: Prognostic significance of
SAECG after thrombolysis in acute myocardial infarction (CAST Substudy). J Am Coll Cardiol
21(SupplA):273A, 1993.
212.
Quin D, Caref EB, El-Sherif N: Modal gating kinetics of cardiac Na channel induced by Anthopleurin-A.
Biophys J 64:A90,1993.
213.
Kowtha V, Boutjdir M, Caref EB, El-Sherif N, Restivo M: Complex and chaotic dynamics of early
afterdepolarizations in simulated Purkinje fibers. Biophys J 64:A206, 1993.
214.
Boutjdir M, Morgenstern D, Wei Y, Restivo M, El-Sherif N, Siddiqui MAQ: Sacrolemmal protein
changes in canine subacute myocardial infarction. Biophys J 64:A293, 1993.
53
215.
Assadi M, Menhaji S, Assadi M, Caref EB, Boutjdir M, El-Sherif N: Lack of correlation between
ventricular arrhythmia variability and the signal averaged electrocardiogram. Chest. In press.
216.
Turitto G, Ahuja R, Caref E. Bekheit S, Ibrahim B, El-Sherif N: Value of signal averaged ECG and
programmed stimulation for predicting sudden cardiac death in non-ischemic dilated cardiomyopathy.
Circulation 88:I-413, 1993.
217.
Ndrepepa G. Caref EB, Knudson L, Del Greco M. El-Sherif N: Significant effects of noise on spectral
turbulence analysis. Circulation 88: I-412, 1993.
218.
Turitto G, Mansoor S, Rao S, Caref EB, El-Sherif N: A comparative analysis of commercial software for
signal averaged electrocardiography. PACE 17:795,1994.
219.
Turitto G, Rao S, Salciccioli L, Abordo M, El-Sherif N: Electrocardiographic and echocardiographic
correlates of atrial flutter and fibrillation. Circulation 90:I-388, 1994.
220.
Restivo M, Hegazy M, Caref EB, El-Hamami M, Yin H, Brooks R, El-Sherif N: Termination and
prevention of circus movement atrial flutter in the sterile pericarditis model by a novel type III agent,
azimilide (NE-10064). Circulation 90:I-413, 1994.
221.
Rachko M, Boutjdir M, Cai L, El-Sherif N, Siddiqui MAQ: Identification of changes in gene expression
following canine subacute myocardial infarction by differential display of polymerase chain reaction.
Circulation 90:I-425, 1994.
222.
Boutjdir M, Zhang Z-H, Huang B, El-Sherif N: Modulation of transient K outward current by sea
anemone toxin III in cardiac cells. Circulation 90:I-526. 1994.
223.
Zhang Z-H, Boutjdir M, El-Sherif N: A novel slow kinetics 4-AP insensitive K current in rat ventricular
myocytes. Circulation 90:I-582, 1995.
224.
Estes NAM, Zipes DP, El-Sherif N, Venditti FJ, Rosenbaum DS: Electrical alternans during rest and
exercise as predictors of vulnerability to ventricular arrhythmias. J Amer Coll Cardiol 409A, 1995.
225.
Estes NAM, Zipes DP, El-Sherif N, Albrecht P, Wang PJ, Marlow M, Dzurak P, Cohen R: The value of
T-wave alternans and signal-averaged electrocardiogram as predictors of arrhythmia vulnerability. Pace
18:796, 1995.
226.
Caref EB, Nedrepepa G, Yin H, Levin R, El-Sherif N, Restivo M: Improved prediction of local from
distant activation in unipolar epicardial electrograms recorded in ischemic canine myocardium by
discriminant functional analysis. Pace 18:925, 1995.
227.
El-Sherif N, Restivo M, Caref EB, Piracha M: Electrophysiologic mechanisms of Torsade de Pointes
ventricular tachyarrhythmias: Tridimensional mapping of ventricular activation. Circulation 92:1-257,
1995.
228.
El-Sherif N. Yin H, Restivo M, Caref EB: Electrophysiologic mechanisms of spontaneous termination of
sustained reentrant monomorphic ventricular tachycardia in the canine post-infarction heart. Circulation
92:1-641, 1995.
229.
Qin D, Jain P, Boutjdir M, El-Sherif N: Expression of T-type calcium current in remodeled hypertrophied
left ventricle from adult rat following myocardial infarction. Circulation 92:1-587, 1995.
54
230.
Caref EB, Restivo M, Zhang S, Yin H, Piracha M, El-Sherif N: Marked spatial dispersion of
repolarization across the ventricular wall in a model of long QT syndrome and torsade de pointes.
Biophys J 1996:70(02):A277.
231.
Restivo M, Caref EB Choi BR, El-Sherif N, Salama G: Optical mapping of early afterdepolarization
formation in the epicardium of the Langendorff-perfused guinea pig heart. Biophys J 1996: 70(2):A277.
232.
Qin D, Zhang ZH, Jain P, Battula V, Boutjdir M, El-Sherif N: Potassium and calcium currents in
remodeled rat ventricular myocytes followng experimental myocardial infarction. Biophys J 1996
70(2)A275.
233.
El Sherif N, Zhang ZH, Qin D, Jain P: Prolongation of action potential duration and early
afterdepolarizations in single myocytes from post-infarction remodeled left ventricle in the rats. J ACC
1996.
234.
Restivo M, Hegazy M, El-Hamami M, Yin H, Caref EB, Assadi M, Levin R, Brooks RR, El-Sherif N:
Antiarrhythmic efficacy of azimilide dihydrochloride on functional circus movement atrial flutter in the
canine right atrial enlargement model. PACE 1996;19:664.
235.
El-Sherif N, Caref EB, Zhang ZH, Restivo M: Correlation of activation recovery intervals and effective
refractory periods in a model of long QT syndrome. Circulation 1996:94(8):1-642.
236
El-Sherif N, Caref EB, Yin H, Restivo M: The electrophysiologic mechanism of torsade de pointes
arrhythmias in the long QT syndrome. Upstream of genes. Circulation 1996: 94(8):1-203.
237.
Gidhi-Jain M, Huang B, Jain P, El-Sherif N: Alterations in potassiuim channel subunit expression in
experimental postinfarction left ventricular hypertrophied myocardium. Circulation 1996, 94(8):1-127.
238.
Boutjdir M, Chen L.Zhang ZH, Tseng C, DiDonato F, Rashbaum W, Morris W, El-Sherif N, Buyon J:
IgG and affinity purified anti-52kD SSA/Ro antibodies from mothers of children with congenital heart
block induce conduction defects and inhibit Ca Channels in the human fetal heart. Circulation 1996,
94(8):1-593.
239.
Boutjdir M, Chen L, Zhang ZH, Tseng C, DiDonato F, El-Sherif N, Buyon J: Arrhythmogenicity of IgG
from mothers of children with congenital heart block. Circulation 1996 94(9):1-714.
240.
G. Turitto, N. El-Sherif: Sudden Death risk assessment: late potentials (abstr). I Cardiovasc Diag Proc,
14:82, 1997.
241.
B. Bandarizadeh, M. Abordo, M. Pizzarelli, L. Salciccioli, N. El-sherif, G. Turitto: Electrocardigraphic
versus echocardiographic markers for recurrent atrial fibrillation and flutter (abstr). PACE, 20 (Suppl II):
1569, 1997.
242.
Boutjdir M, Miranda E, Tseng CE, Mayzel J, El-Sherif N: Role of B-isoform of 52-D-Ro in congenital
heart block. Circulation 96: I-9, 1997.
243.
Caref EB, Stoyanovsky V, Cohen RJ, El-Sherif N: Incidence of T-wave alternans in normal subjects and
effect of heart rate on onset. Circulation 96: I-582, 1997.
244.
Chen L, Al-Mussawir H, El-Sherif N, Boutjdir M: Reduced L-type current density in mouse heart with
autoimmune-associated AV-conduction abnormalities. Circulation 96: I-423, 1997.
55
245.
Chinushi M, Restivo M, Caref Eb, Nollo G, Stoyanovasky V, El-Sherif N: Relation of surface QT/T-wave
alternans to repolarization in the long QT syndrome (LQTS). Role of left ventricular M-cells. Circulation
96: I-325, 1997.
246.
G. Turitto, E.B. Caref, R. Pedalino, G. El-Attar, M. Helal, A. Mohamed, V. Stoyanovsky, N. El-Sherif:
Comparison of heart rate at onset of T-wave alternans in normals and in patients with ventricular
tachyarrhythmias. Circulation 98(Suppl I) I-647, 1998.
247.
Vazquez R, Caref EB, Torres F, Reina M, El-Sherif N: Comparison of acceleration spectrum analysis with
other time- and frequency-domain analysis of the signal-averaged electrocardiogram in normal and in
myocardial infarction (abstr) Pace, 21:836, 1998.
248.
El-Sherif N, Chinushi M, Restivo R, Caref EB: Electrophysiologic basis of the arrhythmogenecity of
short-long cardiac sequences that precede ventricular tachyarrhythmias in the long QT syndrome. (abstr)
Pace, 21:852, 1998.
249.
Chinushi M, Restivo M, Caref EB, Nollo G, El-Sherif N: The electrophysiologic basis of
arrhythmogencity of QT/T alternans in the long QT syndrome (abstr) Pace, 21:854, 1998.
250.
Restivo M, Caref EB, Cho B-R, Kozhevnikov D, Chinushi M, El-Sherif N, Salama G: Repolarization
gradient reversal in the long QT syndrome. (abstr) Pace,21:856, 1998.
251.
Gidh-Jain M, Huang B, El-Sherif N: Alterations in ionic channel/connexin expression after myocardial
infarction: molecular basis of arrhythmogenesis (abstr): Pace, 21:877, 1998.
252.
El-Sherif N: QT prolongation/dispersion/alternans. Different aspects of similar pathophysiology. Arch.
Mal. Coeur-Vaissaux 91(III):114, 1998.
253.
El-Sherif N: Electrophysiologic basis of torsade de pointes. Arch. Mal. Coeur. Vassaux 91(III):26, 1998.
254.
El-Sherif N: Non-invasive electrophysiology. The new algorithm. An update. Arch. Mal. Coeur. Vassaux
91 (III):113, 1998.
255.
Chinushi M, Caref EB, Restivo M, El-Sherif N: QT/T alternans and arrhythmias in the long QT
syndrome. Circulation 98: I-10, 1998.
256.
Chen L, El-Sherif N, Mochly-Rosen D, Boutjdir M: V1-region-derived peptide of  PKC and C2 –regionderived peptide of  PKC regulate cardiac Ca channels. Circulation, 98: I-233, 1998.
257.
Gold M, Bloomfield DM, Anderson KP, Wilber DJ, El-Sherif N, Estes MM, Groh WJ, Kaufman ES,
Greenberg ML, Cohen RS: T-wave alternans predicts arrhythmia vulnerability in patients undergoing
electrophysiology study. Circulation 98: I-647, 1998.
258.
Huang B, Qin D, Gidh-Jain M, Boutjdir M, El-Sherif N: Spatial alterations of Kv channel and connexin
43 expression and K+ current density of post-infarction remodeled left ventricle. Circulation, 98: I-697,
1998.
259.
Huang B, Deng L, Qin D, Boutjdir M, El-Sherif N: Reexpression of T-type Ca2+ channel gene and current
in post-infarction remodeled rat left ventricle. Circulation, 98: I-840, 1998.
56
260.
El-Sherif N, Chinushi M, Caref EB, Restivo M: Electrophysiologic mechanism of the characteristic
electrocardiographic morphology of Torsade de Pointes tachyarrhythmias in the long QT syndrome.
Circulation 96: I-555, 1999.
261.
Hu K, El-Sherif N, Mochly-Rosen D, Boutjdir M. Evidence of functional regulation of cardiac Ca
channels by ePKC using specific peptides activator and inhibitor of ePKC. Circulation 1999; 100: (18)I.
262.
Chatpande A, Qu Y, El-Sherif N, Boutjdir M: IgG from mothers of infants with congenital heart block
immunoreact with sacrolemma of human fetal cardiac mypcytes. PACE. In press.
263.
Qu Y, Chatpandi A, El-Sherif N, Boutjdir M: Protein and RNA exression of Na/Ca exchanges in the
developing human fetal heart. PACE, In press.
264.
Turitto G, Kim I, Alakhras M, Pedalino R, El-Attar G, El-sherif N: Same-day reproducibility of noninvasive assessment of T-wave alternans during bicycle exercise Test. PACE, In press.
265.
Restivo M, Caref EB, Salama G, El-Sherif N: Mechanism of discordant alternans in the guinea pig LQT3
model. PACE, In press
266.
Huang B, Deng L, Qin D, Boutjdir M, El-Sherif N. Time and region dependent stimulation of stressactivated miotogen-activated protein kinase subfamilies folowing myocaridal ischemia. Pace 2000
;23:621.
267.
Bloomfield DM, Gold MR, Anderson KP, Wilber D, El-Sherif N, Estes M, Groh WJ, Kauffman ES,
Greenbers ML,Rosenbaum DS, Dabbous OH, Cohen RJ. T wave alternans predicts independent events
independent of ejection fraction and etiology of heart disease in patients undergoing electrophysiologic
testing for evaluation of known or suspected ventricular arrhythmias. Pace 2000; 23: 593.
268.
Restivo M, Levere RO, Kozhevnikov DO, El-Sherif N, Boutjdir M, Kappas A. Optical mapping study of
the protective effect of the heme oxygenase inhibitor Sn-Mesoporphyrin in the ischemic rabbit heart.
Circulation 2000; 102: 11-339.
269.
Keli H, El-Sherif N, Boutjdir M. Ionic Basis for Sinus Bradycardia in Congenital Heart Block. Presented
at the 73rd Annual Meeting of the American Heart Association, New Orleans, Louisiana, November 611,2000.
270.
Chinushi M, Kozhevnikov D, Caref EB, Restivo M, El-Sherif N. Mechanism of the arrhythmogenecity of
discordant QT/A alternans. J Am Coll Cardiol 2001; 37: 91A.
271.
Yamamoto K, Kozhevnikov D, Robotis D, Restivo M, El-Sherif N. Mechanism of enhanced susceptibility
of hypertrophied heart to acquired torsade de pointes arrhythmias. J Am Coll Cardiol 2001; 37: 92A.
272.
Juratli NM, Tchou PJ, Chung MK, Sparker J, Pedalino RP, El-Sherif N, Turitto G. Implantable
cardiovertor defibrillator may not improve survival in patients with malignant ventricular
tachyarrhythmias and end-stage renal disease. Pace 2001; 24: 569.
273.
El-Sherif N. The JAK-STAT and Post-infarction remodeling. J Heart Failure, 2002; 7:4..
274.
Kozhevnikov D, Restivo M, El-Sherif N. Mechanism of enhanced arrhythmogenicity of acute ischemia
in the hypertrophied heart. Circulation 2002; 106, Suppl II: II-128.
275.
El-Adawi H, Deng L, Tramontano A, Smith S, Mascareno e, Gengul K, Castillo R, El-Sherif N. The
functional role of the JAK-STAT pathway in post-infarction remodeling. Circulation 2002, 106, Suppl II:
II-258.
57
276.
Tramontano AF, Deng L, Smith SJ, El-Adawi H, El-Sherif N. Inhibition of the JAK-STAT pathway
augments apoptosis in the ischemic myocardium. 10th Euro conference on Apoptosis “Charming to
Death”. Institute Pasteur, Paris, France, 2002, pp.
277.
Tramontano AF, Muniyappa R, Black AD, Lingam D, Deng L, Sowers JR, Cutaia M, El-Sherif N.
Recombinant human erythropoietin protects neonatal cardiac myocytes from hypoxia induced apoptosis.
Circulation 2003;108:IV-115.
278.
Lakireddy V, Baweja B, Baynham T, El-Sherif N. Ischemia/reperfusion induced intracellular calcium
oscillations in the intact heart:Relation to arrhythmogenesis. J Amer Coll Cardiol2004;43:128A.
279.
Turitto G, Houy S, Gupta R, Pedalino R, El-Sherif N. Right ventricular but not biventricular pacing
increases markers of ventricular electrical vulnerability. J Amer Coll Cardiol 2004;43:149A.
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