Medical Diagnosis Decision-Support System: Optimizing Pattern Recognition of Medical Data Dr. W. Art Chaovalitwongse Assistant Professor, Department of Industrial and Systems Engineering Rutgers University Faculty Fellow, Center for Supply Chain Management, Rutgers Business School Faculty Member, Center for Advanced Infrastructure & Transportation (CAIT) Member, Center for Discrete Mathematics & Theoretical Computer Science (DIMACS) Abstract: In this presentation, I will discuss some recent advances in optimization and data mining used to develop a new pattern recognition framework. This work relates to medical data signal processing apparatus and computational framework, where optimization and data mining techniques are employed to analyze medical data as advanced medical decision-support systems. The ultimate goal of this research is to improve the current medical diagnosis and prognosis by assisting the physicians in recognizing (data-mining) abnormality patterns in medical data, which are usually encrypted spatially and temporally. The diagnosis of epilepsy and brain disorders is a case point in this study. We have developed several optimization approaches in attempt to predict seizures and localize the abnormal brain area initiating the seizures as well as identify if the patients have epilepsy or other brain disorders. If time permits, I will discuss other applications of this framework. Bio: Dr. Wanpracha Art Chaovalitwongse is an Assistant Professor of Industrial and Systems Engineering at Rutgers University where he has been on the faculty since 2005. He received M.S. and Ph.D. degrees in Industrial and Systems Engineering from University of Florida in 2000 and 2003. He previously worked as a Post-Doctoral Associate in the NIH-funded Brain Dynamics Laboratory, Brain Institute and in the departments of Neuroscience and Industrial and Systems Engineering at University of Florida. Before joining Rutgers, he worked for one year at the Corporate Strategic Research, ExxonMobil Research & Engineering, where he managed research in developing efficient mathematical models and novel statistical data analyses for upstream and downstream business operations. His research interests include optimization, data mining, and decision making models with applications in brain diagnosis, computational biology, information retrieval, network routing, supply chain and logistics. His research has been supported by the National Science Foundation, Cisco, ExxonMobil, Rutgers Academic Excellence Fund, Rutgers Computing Coordination Council, and NJ Schools Development Authority. His academic honors include 2006 National Science Foundation (NSF) CAREER Award, 2008 & 2004 William Pierskalla Best Paper Award for research excellence in Operations Research and Health Care applications by INFORMS (Institute for Operations Research and the Management Sciences), 2007 Notable Alumni of King Mongut’s Institute Technology at Ladkrabang, and 2003 Annual Award for Excellence in Research by the Industrial and Systems Engineering Department, University of Florida. He holds one US patent and one international patent in new seizure prediction algorithms.