Medical Prescriptions o Written order by doctor directing for drugs to be dispensed in stated forms for a particular patient Doctor, dentist o o o o o Used as evidence in the court of law In PI, illegal to prescribe regulated drugs without prescription Should be written plainly Simple or compound Simple - one ingredient - parasetimol Compound - combo of 2 antihistamines Chlorephenomine/ Official Approved by FDA Not drugs that are not registered by your country (fly by night) List of drugs that are official --Extemporaneous - put together a compound in doses suited to disease Cream or lotion by two ingredients Aka non official -- not usual way of prescribing it Doctors mix a lot of ingredients, but it's allowed; not harmful Anti-cough, congested --- more convenient for patient to take it Structure o o o o o Patient's name Age Will guide the pharmacist 5 year old boy given a capsule; pharmacist feels that boy can't take capsule; makes call to doctor and tells him the situation of the boy's age Address Pharmacist makes a mistake - don't give whole dosage that you paid for; address makes you look for patient Date Don't want to give another refill Important because you have to identify the name Helpful to patient, relatives Mom has 3 kids; need to know which med is for which kid Helpful to even the pharmacist --- who may have forgot who the medicine is for o Rx - superscription Symbol Recipe in latin; take though ---this is the medicine that the patient will be taking Rx pad aka prescription pad o Inscription Names - single, compound Amount of remedial agents prescribed And appropriate vehicle to be take by the patient Basis - drugs from which dr. expects true remedial effect Parasetimol -- lowers body temp (true effect) Main factor Adjuvant Inc or intensify the action; several drugs that synerge the parasetimol Corrective to those other drugs to minimize the undesirable effect of basis Flavoring agents Orange, banana flavors to disguise the unattractive tastes But some drugs just not palatable o Subscription Embodies the Dr's direction to pharmacist as to method and of preparation of drugs and amount of the drug Only preparation and number of pills dispensed Example --- in capsule SIS - Capsule can be in suspension (syrup) Too much to sell; should be in bottle depending on Two bottles of remedial agent Could be in cream, in solution, in lotion form, in powder form o Signature aka S If you look at prescription given, no signature given But some others like the one shown in manual has it Not dr's signature Direction of doctor to the patient; if child, direction to guardian, or if patient is hospitalized, direction to hospital personnel To save money, some nurses sent to the house ---sig. is given to the nurse Includes how the patient has to take it One time, with glass of water, time of administration, frequency Example - take 1 capsule every 8 hours for one week; get this when you have computed the medication that you will prescribe; have to justify these directions Not the certification by the physician - finally guar o Cert by Physician License number Official signature that you're certifying the Rx Different Kinds of Prescription in Philippines punishable by Law o Violative prescription Instead of generic name written, you write down the brand name Generic name not legible Brand name is indicated, but you add another word wherein dr. doesn't want pharmacist to change brand name ---- "no substitution please" Have to give patient or buyer chance to choose his own brand name o Erroneous prescription Where brand name receives the generic name Ex -- write a big Amoxil 50 mg; and a tiny little amoxycilin (tiny words) Generic name is in parenthesis More than one drug product is prescribed in order not to waste your space on the Rx paper Economical o Impossible prescription When only the generic name is written but NOT legible; pharmacist cannot read it (impossible to read); hence the term "chicken scratch" Generic name doesn't correspond to the brand name Amoxycillin (500 mg) and you put ventolin You know they don't coincide; doctor should be penalized When both generic and brand name are not legible They want you to buy in his drug store; only staff members can read it; others can't read it When drug prescribed that's not registered with the BFAD Even if the generic name is already approved by BFAD, but if there's no such thing as brand (not registered); whether brand name or generic name Impossible = it doesn't exist o How to differentiate generic vs. brand name Generic - true name of the remedial agent Brand name --- name given by drug company Example -- amoxycilin - generic; amoxyl - brand Amoxycilin - comes with dozens of brand names in some countries Some opinions that doctors use patients just to become rich; losing tenderness and warmth to them Correct Prescription o Name of patient o Age o Date o Address o o Superscription Inscription If you don't write brand name, it's still correct If you do, it should be smaller than generic and in parenthesis Can't be reversed (erroneous) o o Capsule - and amount Signature Direction to patient "one capsule every 8 hours for 1 week" Last Tuesday, Dr. Formalino gave also abbreviations; do not give abbreviations to patients ---- Prn (if necessary) - Read and know all abbreviations ----- P c4 PRN, STAT, OU Certification Usually prescriptions are copied; not required because you have your own index card for each patient -- own file --- contains diagnosis that only you know and understand o Some have blue, yellow copy -- - so that the drug company can reimburse you for how many drugs you prescribed o If dr. didn't indicate brand name, pharmacist can offer other brand names to the patient; pharmacist has privilege to offer it; patient not obligated to buy it though -- he wants a cheaper one o Not recommended to write more than one brand name Dr. tells patient to buy cheaper generic one for patient to choose written on a different Rx paper Ex combipack for TB or entepack -----all the same Practical o o Take a paper --A 20 year old man came to clinic due to fever and cough for 5 days duration; Adult patient - use empirical o Pedia patient example 8 year old boy came due to fever and cough for 5 days Diagnosis - bronchopneumonia Give amoxycillin and parasetimol 2 prescriptions Amoxycillin usually given btw range of 50-100 kg BW (whole of total dose you give each day) Preparation -- 250 mg/5ml or one teaspoon (suspension/syrup_ Bottle -- 60 ml 1 teaspoon = 5 ml 25 kg How many teaspoons per day if use 250 mg = 2500 g How many ml do you need a day? Computation Have 5 ml. how many do you need per day? 10 (5ml) or 10 teaspoons Formula 2,500ml/x = 250 ml/5 ml X = 50 ml or 10 teaspoons 1 teaspoon = 5 ml Can you give 3 teaspoons every 8 hours? 2 teaspoons every 8 hours? ----still in the range Parasetimol ----> Give 10-20 mg per kg per dose Usually given every 4 hours due to fever; for pain PRN (if necessary) In syrup ---at age 8 125 mg per teaspoon (5ml) 60 ml or 120 ml Also 250 mg per teaspoon (5ml) 250/5 = x/10 Higher volume, so cheaper Choose between the two Tablet --- 8 years 325 mg per tablet 500 mg per tablet Up to you what to us Computation Boy weighs 25 kg body weight Need 10 teaspoons a day; 7 days --- need 70 teaspoons o How to convert in bottles? o 12 teaspoons 6 bottles ----72 teaspoons o when you say 4 times a day, you tell the patient during times he's not sleepy Only awake hours 6 times, you assume patient is awake at all times Wake at 6, 12, 6, 12 midnight o Use every 6 hours Prescription Written E.R. Caangay, MD Emergency Medicine 6/29/06 Name Address Rx o Subscription i. amoxicillin o o 250 mg/5ml 60 ml bottles # 7 Signature 2 1/2 teaspoons every 6 hours for 7 days subscription Certification Parasetimol o Name, date, address o superscription o Subscription Paracetamol 250 mg/5m 120 ml bottlel o Sig Take 1 teaspoons every 4 hours as needed