NAME
Evelyn Camon
POSITION
GOA Project Coordinator
ADDRESS
EMBL Outstation - Hinxton,
European Bioinformatics Institute,
Wellcome Trust Genome Campus, Hinxton,
Cambridge, CB10 1SD, United Kingdom
Phone Work: +44 (0)1223 494 465
Fax: +44 (0)1223 494 468
Email
camon@ebi.ac.uk
Research Projects
GOA is a project run by the European Bioinformatics Institute that aims to provide assignments of
gene products to the Gene Ontology (GO) resource.
The goal of the Gene Ontology Consortium is to produce a dynamic controlled vocabulary that can
be applied to all organisms, even while knowledge of gene and protein roles in cells is still
accumulating and changing. In the GOA project, this vocabulary will be applied to a non-redundant
set of proteins described in the UniProt Resource (Swiss-Prot/TrEMBL/PIR-PSD) and Ensembl
databases that collectively provide complete proteomes for Homo sapiens and other organisms.
In the first stage of this project, GO assignments have been applied to a data set representing the
human proteome by a combination of electronic mappings and manual curation. Subsequently, GO
assignments for all complete and incomplete proteomes that exist in UniProt have been provided.
GOA will be updated monthly in accordance with the latest data released by the primary data
sources.
Recent Publications
Lee V., Camon E., Dimmer E., Barrell D., Apweiler R. (2005)
Who tangos with GOA? Use of Gene Ontology Annotation (GOA) for biological interpretation of ‘omics’ data and for validation of automatic annotation tools. In Silico Biol. 5: 0002 (2005).
Camon E., Barrell D., Lee V., Dimmer E., Apweiler R. (2004)
The Gene Ontology Annotation (GOA) Database - An integrated resource of GO annotations to the
UniProt Knowledgebase. In Silico Biology 4(1): 5-6 (2004).
Camon, E., Magrane, M., Barrell, D., Lee V., Dimmer, E., Maslen, J., Binns, D., Harte, N., Lopez,
R., Apweiler R. (2004)
The Gene Ontology Annotation (GOA) Database: sharing knowledge in Uniprot with Gene
Ontology. Nucleic Acids Research Jan 1 32(1): D262-D266 (2004).
Gene Ontology Consortium* (2004)
*Current members of the GO Consortium are: M. A. Harris, J. Clark, A. Ireland, J. Lomax (GO-EBI,
Hinxton, UK); M. Ashburner, R. Foulger (FlyBase, Department of Genetics, University of
Cambridge, Cambridge, UK); K. Eilbeck, S. Lewis, B. Marshall, C. Mungall, J. Richter, G. M. Rubin
(BDGP, UC-Berkeley, Berkeley, CA, USA), J. A. Blake, C. Bult, M. Dolan, H. Drabkin, J. T. Eppig,
D. P. Hill, L. Ni, M. Ringwald (MGI, Jackson Laboratory, Bar Harbor, ME, USA); R. Balakrishnan, J.
M. Cherry, K. R. Christie, M. C. Costanzo, S. S. Dwight, S. Engel, D. G. Fisk, J. E. Hirschman, E. L.
Hong, R. S. Nash, A. Sethuraman, C. L. Theesfeld (SGD, Department of Genetics, Stanford
University, Stanford, CA, USA); D. Botstein, K. Dolinski, B. Feierbach (Genomics Institute,
Princeton University, Princeton, NJ, USA); T. Berardini, S. Mundodi, S. Y. Rhee (TAIR, Carnegie
Institution, Department of Plant Biology, Stanford, CA, USA); R. Apweiler, D. Barrell, E. Camon, E.
Dimmer, V. Lee (GOA database, UniProt, EBI, Hinxton, UK); R. Chisholm, P. Gaudet, W. Kibbe
(DictyBase, Northwestern University, Chicago, IL, USA); R. Kishore, E. M. Schwarz, P. Sternberg
(WormBase, California Institute of Technology, Pasadena, CA, USA); M. Gwinn, L. Hannick, J.
Wortman (Institute for Genome Research, Rockville, MD, USA); M. Berriman, V. Wood (Wellcome
Trust Sanger Institute, Hinxton, UK); N. de la Cruz, P. Tonellato (RGD, Medical College of
Wisconsin, Milwaukee, WI, USA); P. Jaiswal (Gramene, Department of Plant Breeding, Cornell
University, Ithaca, NY, USA); T. Seigfried (Maize DB, Iowa State University, Ames, IA, USA); R.
White (Incyte Genomics, Palo Alto, CA, USA).
The Gene Ontology (GO) database and informatics resource. Nucl. Acids. Res. 2004 32: D258D261.
Camon E, Barrell D, Lee V, Dimmer E. and Apweiler R.
Gene Ontology Annotation Database - An integrated resource of GO annotations to UniProt
Knowledgebase. In Silico Biol., 4: 0002 (2003).
Brooksbank C, Camon E, Harris MA, Magrane M, Martin M, Mulder N, O'Donovan C, Parkinson H,
Tuli M, Apweiler R, Birney E, Brazma A, Henrick K, Lopez R, Stoesser G, Stoehr P, and Cameron
G.
The European Bioinformatics Institute's data resources. Nucleic Acids Research, 31: 43-50 (2003).
Camon E, Barrell D, Brooksbank C, Magrane M and Apweiler R.
The Gene Ontology Annotation (GOA) Project: Application of GO in SWISS-PROT, TrEMBL and
InterPro. Comp Funct Genom., 4: 71-74 (2003).
Camon E*, Magrane M*, Barrell D, Binns D, Fleischmann W, Kersey P, Mulder N, Oinn T, Maslen J,
Cox A and Apweiler R.
The Gene Ontology Annotation (GOA) project: implementation of GO in Swiss-Prot, TrEMBL and
InterPro. Genome Research Apr; 13 (4): 662-672 (2003).
Biswas M, O'Rourke J F, Camon E, Fraser G, Kanapin A, Karavidopoulou Y, Kersey P, Kriventseva
E, Mittard V, Mulder N, Phan I, Servant F, Apweiler R.
Applications of InterPro in protein annotation and genome analysis. Brief Bioinform. Sept; 3 (3):
285-295 (2002).
N.B. * denotes equal contribution.