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Cell Communication and Signaling
Cell Communication and Signaling main menu
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Featured series: Short linear motifs - the unexplored frontier
of the eukaryotic proteome
Short linear motifs (SLiMs) guide the life of proteins from translation to destruction,
directing their interactions, modification state, localisation and stability. The human proteome
has been estimated to contain more than a hundred thousand – possibly up to a million – SLiM
instances. Yet, to date, only a small fraction of the complete motif repertoire has been
characterised and we still know relatively little about these elegantly simple protein interaction
modules.
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1. Research
Feedback activation of neurofibromin terminates growth factor-induced
Ras activation
Anne Hennig, Robby Markwart, Katharina Wolff, Katja Schubert, Yan Cui, Ian A. Prior,
Manuel A. Esparza-Franco, Graham Ladds and Ignacio Rubio
Published on: 9 February 2016
2. Research
Cisplatin-induced mesenchymal stromal cells-mediated mechanism
contributing to decreased antitumor effect in breast cancer cells
Svetlana Skolekova, Miroslava Matuskova, Martin Bohac, Lenka Toro, Lucia Demkova,
Jan Gursky and Lucia Kucerova
Published on: 12 January 2016
3. Methodology
MSC surface markers (CD44, CD73, and CD90) can identify human MSCderived extracellular vesicles by conventional flow cytometry
Teresa L. Ramos, Luis Ignacio Sánchez-Abarca, Sandra Muntión, Silvia Preciado, Noemí
Puig, Guillermo López-Ruano, Ángel Hernández-Hernández, Alba Redondo, Rebeca
Ortega, Concepción Rodríguez, Fermín Sánchez-Guijo and Consuelo del Cañizo
Published on: 12 January 2016
4. Review
GPR91: expanding the frontiers of Krebs cycle intermediates
Matheus de Castro Fonseca, Carla J. Aguiar, Joao Antônio da Rocha Franco, Rafael N.
Gingold and M. Fatima Leite
Published on: 12 January 2016
5. Review
Phase separation in biology; functional organization of a higher order
Diana M. Mitrea and Richard W. Kriwacki
Published on: 5 January 2016
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Most accessed articles
Most accessed articles RSS
1. Research
MicroRNA-188 suppresses G1/S transition by targeting multiple
cyclin/CDK complexes
Jiangbin Wu, Qing Lv, Jie He, Haoxiang Zhang, Xueshuang Mei, Kai Cui, Nunu Huang,
Weidong Xie, Naihan Xu and Yaou Zhang
Published on: 11 October 2014
2. Review
Different populations and sources of human mesenchymal stem cells
(MSC): A comparison of adult and neonatal tissue-derived MSC
Ralf Hass, Cornelia Kasper, Stefanie Böhm and Roland Jacobs
Published on: 14 May 2011
3. Review
Interaction of tumor cells with the microenvironment
Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert and Ralf Hass
Published on: 13 September 2011
4. Research
Slit2N and Robo4 regulate lymphangiogenesis through the VEGFC/VEGFR-3 pathway
Jinlong Yu, Xuefeng Zhang, Paula M Kuzontkoski, Shuxian Jiang, Weiquan Zhu, Dean
Y Li and Jerome E Groopman
Published on: 7 April 2014
5. Research
Exosomes are natural carriers of exogenous siRNA to human cells in vitro
Tatyana A Shtam, Roman A Kovalev, Elena Yu Varfolomeeva, Evgeny M Makarov,
Yury V Kil and Michael V Filatov
Published on: 18 November 2013
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Editor's profile
Stephan Feller, Editor-in-Chief
Stephan Feller holds a professorship in Tumor Biology at the Institute of Molecular Medicine of
the Martin-Luther-University Halle-Wittenberg, Germany. Prior to this appointment, he was a
Principal Investigator at the Weatherall Instuitute of Molecular Medicine (WIMM) in Oxford
and a Lecturer at the University of Oxford for over a decade.
Stephan graduated in 1989 with a Diploma in Biology after studying at Kaiserlautern and
Heidelberg. In 1994 he obtained a PhD in biochemistry and cell biology from The Rockefeller
University, New York. He then stayed on for another year as a postdoctoral fellow, again in the
laboratory of renowned cancer virologist Hidesaburo Hanafusa, before moving to Würzburg
University, where he established an independent junior research group. Starting with his doctoral
research, Stephan has been interested in the molecular signaling mechanisms that allow cancer
cells to develop and persist.
In 2001 he moved to Oxford to continue and extend his cancer cell research into structural
biology and other biophysical studies. In Oxford he also started to dissect the molecular
differences that underlie the development of individual human cancers, with a focus on protein
kinases and related signaling proteins. For this, the research team analyses large panels of tumor
cell lines derived from colorectal cancers and head and neck squamous cell carcinomas.
His most recent work aims to understand the molecular architecture of signaling protein
complexes and networks. He has put forward the N-terminal folding nucleation (NFN)
hypothesis, which would seem to explain how complex signals are molecularly computed in a
highly coordinated manner within multi-protein complexes assembled on intrinsically disordered
proteins.
Aims and scope
Cell Communication and Signaling is an open access journal that encompasses all basic and
translational aspects of cellular communications and signaling pathways in normal and
pathological conditions.
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Article collections
Review series
Bacterial pathogen - host cell interactions
Edited by Silja Wessler
Review series
Systems Biology and Medicine
Edited by Stephan Feller and Fred Schaper
Thematic series
Interaction of Helicobacter pylori with its host cell
Edited by Silja Wessler
View all article collections
STS/CCS Honorary Medal
In 2010 the Signal Transduction Society, together with Cell Communication and Signaling,
introduced the STS/CCS Honorary Medal that celebrates the accomplishments of world leaders
in cell signaling research.
Recipients of this Honorary Medal are so far:
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Mina Bissell (2015)
Jules A. Hoffmann (2014)
Klaus Rajewsky (2013)
Carl-Henrik (Calle) Heldin (2012)
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Anthony (Tony) R. Hunter (2011)
Anthony (Tony) J. Pawson (2010)
Lecture series sponsorship
Cell Communication and Signaling sponsors the International Lecture Series 'Disease Biology
and Molecular Medicine', which is organized by the Medical Faculty of the Martin-LutherUniversity Halle-Wittenberg with support from the City of Halle.
School sponsorship
Cell Communication and Signaling sponsors a primary school event promoting intercultural
understanding (September 2014, Grundschule Kröllwitz, Halle, Germany)
Cell Communication and Signaling fund matches the fundraising effort by the Christian-WolffSchool in Halle (Saale), Germany, to support teacher education for the Gaiatreeschool in India.
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Impact Factor: 3.378
ISSN:
1478-811X
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