Skip to main content Advertisement Menu Search Search Publisher main menu Journals Submissions Publishing services About My Account Follow BioMed Central Twitter Facebook Cell Communication and Signaling Cell Communication and Signaling main menu Home About Articles Featured series: Short linear motifs - the unexplored frontier of the eukaryotic proteome Short linear motifs (SLiMs) guide the life of proteins from translation to destruction, directing their interactions, modification state, localisation and stability. The human proteome has been estimated to contain more than a hundred thousand – possibly up to a million – SLiM instances. Yet, to date, only a small fraction of the complete motif repertoire has been characterised and we still know relatively little about these elegantly simple protein interaction modules. Read More Articles Recent Most accessed Recent articles Recent articles RSS 1. Research Feedback activation of neurofibromin terminates growth factor-induced Ras activation Anne Hennig, Robby Markwart, Katharina Wolff, Katja Schubert, Yan Cui, Ian A. Prior, Manuel A. Esparza-Franco, Graham Ladds and Ignacio Rubio Published on: 9 February 2016 2. Research Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells Svetlana Skolekova, Miroslava Matuskova, Martin Bohac, Lenka Toro, Lucia Demkova, Jan Gursky and Lucia Kucerova Published on: 12 January 2016 3. Methodology MSC surface markers (CD44, CD73, and CD90) can identify human MSCderived extracellular vesicles by conventional flow cytometry Teresa L. Ramos, Luis Ignacio Sánchez-Abarca, Sandra Muntión, Silvia Preciado, Noemí Puig, Guillermo López-Ruano, Ángel Hernández-Hernández, Alba Redondo, Rebeca Ortega, Concepción Rodríguez, Fermín Sánchez-Guijo and Consuelo del Cañizo Published on: 12 January 2016 4. Review GPR91: expanding the frontiers of Krebs cycle intermediates Matheus de Castro Fonseca, Carla J. Aguiar, Joao Antônio da Rocha Franco, Rafael N. Gingold and M. Fatima Leite Published on: 12 January 2016 5. Review Phase separation in biology; functional organization of a higher order Diana M. Mitrea and Richard W. Kriwacki Published on: 5 January 2016 View all articles Most accessed articles Most accessed articles RSS 1. Research MicroRNA-188 suppresses G1/S transition by targeting multiple cyclin/CDK complexes Jiangbin Wu, Qing Lv, Jie He, Haoxiang Zhang, Xueshuang Mei, Kai Cui, Nunu Huang, Weidong Xie, Naihan Xu and Yaou Zhang Published on: 11 October 2014 2. Review Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC Ralf Hass, Cornelia Kasper, Stefanie Böhm and Roland Jacobs Published on: 14 May 2011 3. Review Interaction of tumor cells with the microenvironment Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert and Ralf Hass Published on: 13 September 2011 4. Research Slit2N and Robo4 regulate lymphangiogenesis through the VEGFC/VEGFR-3 pathway Jinlong Yu, Xuefeng Zhang, Paula M Kuzontkoski, Shuxian Jiang, Weiquan Zhu, Dean Y Li and Jerome E Groopman Published on: 7 April 2014 5. Research Exosomes are natural carriers of exogenous siRNA to human cells in vitro Tatyana A Shtam, Roman A Kovalev, Elena Yu Varfolomeeva, Evgeny M Makarov, Yury V Kil and Michael V Filatov Published on: 18 November 2013 View all articles Editor's profile Stephan Feller, Editor-in-Chief Stephan Feller holds a professorship in Tumor Biology at the Institute of Molecular Medicine of the Martin-Luther-University Halle-Wittenberg, Germany. Prior to this appointment, he was a Principal Investigator at the Weatherall Instuitute of Molecular Medicine (WIMM) in Oxford and a Lecturer at the University of Oxford for over a decade. Stephan graduated in 1989 with a Diploma in Biology after studying at Kaiserlautern and Heidelberg. In 1994 he obtained a PhD in biochemistry and cell biology from The Rockefeller University, New York. He then stayed on for another year as a postdoctoral fellow, again in the laboratory of renowned cancer virologist Hidesaburo Hanafusa, before moving to Würzburg University, where he established an independent junior research group. Starting with his doctoral research, Stephan has been interested in the molecular signaling mechanisms that allow cancer cells to develop and persist. In 2001 he moved to Oxford to continue and extend his cancer cell research into structural biology and other biophysical studies. In Oxford he also started to dissect the molecular differences that underlie the development of individual human cancers, with a focus on protein kinases and related signaling proteins. For this, the research team analyses large panels of tumor cell lines derived from colorectal cancers and head and neck squamous cell carcinomas. His most recent work aims to understand the molecular architecture of signaling protein complexes and networks. He has put forward the N-terminal folding nucleation (NFN) hypothesis, which would seem to explain how complex signals are molecularly computed in a highly coordinated manner within multi-protein complexes assembled on intrinsically disordered proteins. Aims and scope Cell Communication and Signaling is an open access journal that encompasses all basic and translational aspects of cellular communications and signaling pathways in normal and pathological conditions. Read more Article collections Review series Bacterial pathogen - host cell interactions Edited by Silja Wessler Review series Systems Biology and Medicine Edited by Stephan Feller and Fred Schaper Thematic series Interaction of Helicobacter pylori with its host cell Edited by Silja Wessler View all article collections STS/CCS Honorary Medal In 2010 the Signal Transduction Society, together with Cell Communication and Signaling, introduced the STS/CCS Honorary Medal that celebrates the accomplishments of world leaders in cell signaling research. Recipients of this Honorary Medal are so far: Mina Bissell (2015) Jules A. Hoffmann (2014) Klaus Rajewsky (2013) Carl-Henrik (Calle) Heldin (2012) Anthony (Tony) R. Hunter (2011) Anthony (Tony) J. Pawson (2010) Lecture series sponsorship Cell Communication and Signaling sponsors the International Lecture Series 'Disease Biology and Molecular Medicine', which is organized by the Medical Faculty of the Martin-LutherUniversity Halle-Wittenberg with support from the City of Halle. School sponsorship Cell Communication and Signaling sponsors a primary school event promoting intercultural understanding (September 2014, Grundschule Kröllwitz, Halle, Germany) Cell Communication and Signaling fund matches the fundraising effort by the Christian-WolffSchool in Halle (Saale), Germany, to support teacher education for the Gaiatreeschool in India. 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