Format and content of an example case report abstract Oral mucosal neuroma presenting in a patient with Clove syndrome E. A. AKBARI & H. ZAITOUN Paediatric Dentistry, Charles Clifford Dental Hospital, Sheffield, UK Introduction: CLOVE syndrome is a disorder comprising congenital lipomatous overgrowth, vascular malformations and epidermal nevi. It is a recently defined syndrome following reclassification of Proteus syndrome, which is a progressive disease, in contrast to the non-progressive nature of CLOVE. Vascular malformations in CLOVE are typically truncal and there is disregulated adipose tissue deposition, scoliosis and enlarged bony structures. We describe a female with features of CLOVE syndrome and mucosal neuroma of the tongue, not previously described in association with CLOVE syndrome. Case reports: A 14-year-old girl was referred for management of dental trauma, crowding and a 7-month history of three asymptomatic dorsal tongue lesions. Clinical examination revealed skeletal and dental asymmetry with midline shift to the left, enlargement of the maxilla with right-sided macroglosia. There was an enamel-dentine fracture 11, and 23 was buccally displaced and causing soft tissue trauma. There were three soft tissue lesions on the dorsum of the tongue measuring 5 mm in diameter with no ulceration or erythema. Comprehensive dental care under general anaesthesia was undertaken including excisional biopsy of the hyperplastic tongue tissue. Histopathology confirmed mucosal neuroma. Mucosal neuromas have not been previously reported in CLOVE syndrome and may be a new finding or an indication the patient has Multiple Endocrine Neoplasia type 2B for which investigations are currently under way. Comments: Dentists may be the first clinicians to detect oral lesions which present as part of a systemic condition. Further investigation is required to determine the aetiology of mucosal neuroma in this patient. [Extract taken from Int J Paed Dent 2013; Vol 23. Issue Supplement s1: 89]