CURRICULUM VITAE/BIBLIOGRAPHY Brian A. Irving, Ph.D., M.S. PERSONAL INFORMATION Place of Birth: Fort Lauderdale, FL Citizenship: U.S.A. CONTACT INFORMATION Louisiana State University School of Kinesiology 85 Huey P. Long Fieldhouse Baton Rouge, LA 70806 Office: (225) 578-7179 brianairving@lsu.edu PRESENT ACADEMIC RANK AND POSITION 2015-Present Assistant Professor, Louisiana State University, School of Kinesiology EDUCATION 2001-2006 University of Virginia Charlottesville, VA Ph.D., Exercise Physiology GPA: 3.94 2001-2004 University of Virginia Charlottesville, VA M.S., Health Evaluation Science Major: Clinical & Patient-Oriented Research GPA: 3.94 1998-2000 Oregon State University Corvallis, OR B.S., Health and Human Performance Major: Exercise and Sports Science Graduated Summa Cum Laude GPA: 3.99 1996-1998 University of Miami Coral Gables; FL Major: Biochemistry GPA: 3.63 HONORS/AWARDS 1996-1997 1996-1997 1996-1997 1996-1998 1999-2000 1998-2000 1996-2000 2001-2002 2002-2003 2003-2004 2004 2006 2008 2012 E Martinis Scholarship (Bergan Brunswig) Alpha Lambda Delta National Academic Society for Freshmen (University of Miami) National Dean’s List (University of Miami) Jay F. W. Pearson Scholarship (University of Miami) Order of Omega Greek Honor Society (Oregon State University) Golden Key National Honor Society (Oregon State University) Academic Dean’s List (University of Miami and Oregon State University) Curry School of Education Foundation Award (University of Virginia) Dupont Fellowship-Education (University of Virginia) Graduate Fellowship in Education (University of Virginia) Michael Pollock Memorial Grant Finalist (ACSM) SEACSM Doctoral Student Research Award Charter Member of the Mayo Clinic Center for Translational Sciences Activities APS: Endocrinology and Metabolism Section’s New Investigator Award 2013 Power-O2k Laboratory: MiPNet Expert Team in High Resolution Respirometry PREVIOUS PROFESSIONAL POSITIONS AND MAJOR APPOINTMENTS 1996-1997 Biology Laboratory Work Study, Department of Biology, University of Miami, Coral Gables, FL 33124 Mentor: Dr. Dana Kremples, Ph.D. 1999 Undergraduate Research Assistant, Comparative Anatomy Laboratory, Department of Zoology, Oregon State University, Corvallis, OR 97331 Mentor: Dr. Thomas Roberts, Ph.D. 2000 Undergraduate Practicum Student, Human Performance Laboratory, Department of Exercise and Sports Science, Oregon State University, Corvallis, OR 97331, Mentor: Susan Fox, M.S. 2000 Undergraduate Exercise Physiology Intern, Division of Health Promotion & Sports Medicine, Human Performance Laboratory, Oregon Health Sciences University, Portland, OR 97201, Mentors: Dr. Kerry Kuehl, M.D., Kirsten Dulacki, B.S. 2000-2001 Research Assistant II, Division of Health Promotion & Sports Medicine, Oregon Health Sciences University, Portland, OR 97201 Mentors: Dr. Kerry Kuehl, M.D., Dr. Linn Goldberg, M.D., and Dr. Dianne Elliot, MD. 2001-2005 NIH Complementary and Alternative Medicine Predoctoral Fellow, Center for the Study of Complementary and Alternative Therapies, University of Virginia, Charlottesville, VA 22905 Mentors: Drs. Arthur Weltman, Ph.D., Glenn Gaesser, Ph.D., Eugene Barrett, M.D., Ph.D., Ann Gill Taylor, MSN, EdD 2002-2006 Graduate Teaching Assistant, Department of Human Services, Kinesiology Program, University of Virginia, Charlottesville, VA 22905 EDHS 441; Exercise Physiology (Fall 02, 03, 04, 05) EDHS 741; Graduate Exercise Physiology (Guest Lecturer) (Fall 04) EDHS 741L; Graduate Exercise Physiology Laboratory (Spring 03, 04,05, 06) 2002-2006 Memorial Gymnasium Exercise Physiology Laboratory Manager, Department of Human Services, Kinesiology, University of Virginia, Charlottesville, VA 22905 2005-2006 NCAA Certification Chief Report Writer, Department of Athletics, University of Virginia, Charlottesville, VA 22905 2006-2007 NIH Diabetes and Metabolism Postdoctoral Research Fellow Division of Endocrinology, Diabetes, Metabolism, and Nutrition Endocrine Research Unit Mayo Clinic College of Medicine, Rochester, MN 55905 Mentor: Dr. K. Sreekumaran Nair, MD, PhD 2007-2012 NIH Clinical Research Scholar (KL2) Center for Translational Science Activities (CTSA) Mayo Clinic College of Medicine, Rochester, MN 55905 Mentors: Dr. K. Sree Nair, MD, PhD and Dr. Robert Bergen III, PhD 2009-2012 Assistant Professor of Medicine Division of Endocrinology, Diabetes, Metabolism, and Nutrition Mayo Clinic College of Medicine, Rochester, MN 55905 2010-2012 Associate Consultant Division of Endocrinology, Diabetes, Metabolism, and Nutrition Mayo Clinic College of Medicine, Rochester, MN 55905 2012-Present Associate Researcher Division of Endocrinology, Diabetes, Metabolism, and Nutrition Mayo Clinic College of Medicine, Rochester, MN 55905 2012-2015 Clinical Research Scientist Geisinger Obesity Institute Geisinger Health System, Danville, PA 17822 2012-2015 Staff Scientist Weis Center for Research Geisinger Health System, Danville, PA 17822 PROFESSIONAL MEMBERSHIPS AND SOCIETIES (Extramural only) 2002-Present 2003-Present 2003-Present 2004-Present 2006-Present 2010-Present 2013-Present American College of Sports Medicine Obesity Society Researchers against Inactivity-related Disorders (RID) American Diabetes Association Endocrine Society American Physiological Society Mitochondrial Physiology Society AD HOC REVIEWER: Age and Ageing American Journal of Clinical Nutrition American Journal of Physiology: Endocrinology and Metabolism American Journal of Physiology: Regulatory, Integrative and Comparative Physiology Diabetes Diabetes Care Endocrinology Journal of Clinical Endocrinology and Metabolism Journal Nutrition Journal of Sport Rehabilitation Plos One Obesity EDUCATIONAL ACTIVITIES TEACHING: 2002-2006 Graduate Teaching Assistant, Department of Human Services, Kinesiology Program, University of Virginia, Charlottesville, VA 22905 EDHS 441: Exercise Physiology (Fall 02, 03, 04, 05) EDHS 741: Graduate Exercise Physiology (Guest Lecturer) (Fall 04) EDHS 741L: Graduate Exercise Physiology Laboratory (Spring 03, 04, 05, 06) 2007-2012 Invited Lecturer, Mayo Graduate School, Rochester, MN 55905 CTSC 5120: CRU Human Studies Methodologies Course Director: Dr. Nisha Charkoudian CORE 6700: Integrative Physiology Course Director: Dr. Nisha Charkoudian 2009 Group Leader, Mayo Graduate School, Rochester, MN 55905 CTSA Introduction to Clinical & Translational Research Course Director: Dr. Anthony Windebank 2012 Guest Lecturer, Bloomsburg University, Bloomsburg, PA EXERSCI556: Muscular Adaptations Course Director: Dr. Swapan Mookerjee 2013-Present Guest Lecturer, Penn State University, University Park, PA Kinesiology 567: Advanced Exercise Physiology Course Director: Dr. David Proctor 2015-Present Guest Lecturer, Penn State University, University Park, PA Kinesiology 455: Physiological Basis for Exercise as Medicine Course Director: Dr. David Proctor Invited Lectures / Seminars 1. Irving, BA, Brock DW. Obesity, Type 2 Diabetes, Metabolic Syndrome, and Lifestyle Intervention. GNUR 520: Complementary and Alternative Therapies for Health, Graduate School of Nursing, University of Virginia, September 10, 2003. 2. Irving, BA, Anderson, SM, Weltman, JY, Watson-Winfield, DD, Frick, KI, Evans, WS, Veldhuis, JD, Weltman, A. Time of Exercise Initiation Does Not Affect Metabolic and Performance Responses During Acute Exercise. Presented the Graduate Student Presentation Day and Slaughter Lecture, University of Virginia, April 21, 2004. 3. Irving, BA. Measurement and Evaluation: Athletic Performance. University of Virginia’s Strength and Conditioning Symposium (NSCA CME), Understanding Your Sports Medicine Team Member’s Role. University of Virginia, October 8, 2005. 4. Irving, BA, Brock, DW, Davis, CK, Patrie, J, Swift, DL, Barrett, EJ, Gaesser, GA, Weltman, A. Impact of Exercise Intensity on Abdominal Visceral Fat (AVF) and Risk Factors Associated with the Metabolic Syndrome. University of Virginia’s General Clinical Research Center Symposium, November 8, 2005. 5. Irving, BA. Impact of Exercise Intensity on Abdominal Visceral Fat (AVF) and Risk Factors Associated with the Metabolic Syndrome. Washington University, St. Louis, MO, January 24, 2006. 6. Irving, BA. Impact of Exercise Intensity on Abdominal Visceral Fat (AVF) and Risk Factors Associated with the Metabolic Syndrome. Rochester, MN, October 19-20, 2006. 7. Irving, BA. Does DHEA Enhance the Response to Exercise in Postmenopausal Women? Endocrine Research Seminar. Mayo Clinic College of Medicine, May 9, 2007. 8. Irving, BA. Muscle Physiology/Protein Kinetics. CTSC 5120: CRU Human Studies Methodologies. Mayo Clinic College of Medicine, June 6, 2007. 9. Irving, BA, Karakelides, H, Bigelow, M, Short, KR, Kahl, J, Nair, KS. Total and High Molecular Weight Adiponectin and Insulin Action-Impact of Age, Body Composition and Cardiorespiratory Fitness. MN Diabetes Research Day. Mayo Clinic College of Medicine, June 9, 2007. 10. Irving, BA. Effect of Insulin Deprivation on Mitochondrial Function. 13th Annual Mayo-Karolinska Diabetes and Metabolism Meeting. Nice, France, October 19-20, 2007 11. Irving, BA. Introduction to Respiration. CORE 6700: Integrative Physiology. Mayo Clinic College of Medicine, February 5, 2008. 12. Irving, BA. Cellular (Integrative) Metabolism. CORE 6700: Integrative Physiology. Mayo Clinic College of Medicine, February 21, 2008. 13. Irving, BA. Whole-Body and Cellular Bioenergetics. CORE 6700: Integrative Physiology. Mayo Clinic College of Medicine, February 17, 2009. 14. Irving, BA. Potential Counter Measures to Prevent and/or Delay Age-Related Skeletal Muscle Dysfunction. University of Florida’s Institute on Aging. Gainesville, FL, January 11, 2010. 15. Irving, BA. Potential Counter Measures to Prevent and/or Delay Age-Related Skeletal Muscle Dysfunction. University of Oregon. Eugene, OR, January 21, 2010. 16. Irving, BA. Skeletal Muscle Remodeling in Aging: Impact of Exercise Modality. Endocrine Research Seminar. Mayo Clinic. Rochester, MN, December 7, 2010. 17. Irving, BA. Skeletal Muscle Remodeling in Aging: Impact of Exercise Modality. Metabolism Interest Group. University of Utah. Salt Lake City, UT, January 13, 2011. 18. Irving, BA and Ravussin E. Adaptive Thermogenesis and Overfeeding. Role: Session Co-Chair. The Obesity Society Annual Meeting. Orlando, FL, October 3, 2011. 19. Irving, BA. Dose Exercise Training Modality Differential Affect Skeletal Muscle Adaptation in Young and Older Adults? Mayo-Karolinska Institute Research Meeting. December 1-3, 2011. 20. Irving, BA. Skeletal Muscle Remodeling in Aging: Impact of Exercise Training Modality. Penn State University – University Park. Noll Laboratory Research Seminar. September 7, 2012. 21. Irving, BA. Mitochondrial Dysfunction in Aging and its Impact on Fuel Selection. Bjorntorp Symposium. Maastricht, Netherlands. November 7-9, 2012. 22. Irving, BA. Skeletal Muscle Remodeling in Aging: Impact of Exercise Training Modality. Penn State University - Hershey. February 22, 2013. 23. Irving, BA. Shredder Applications in High-Resolution Respirometry. Oroboros O2K Flourometry Workshop – Oburgurgl, Austria. Sept 19 - 22, 2013. 24. Irving, BA. Impact of Exercise Training on Mitochondrial Bioenergetics and Protein Turnover. University of Georgia – Athens, GA. April 9, 2014. 25. Irving, BA. Shredder Applications in High-Resolution Respirometry. Oroboros O2K Flourometry Workshop – University of Pennsylvania, PA. June 2 - 3, 2014. MENTORING: Mrs. Martha Henley, M.Ed.: 2003 to 2004 (M.Ed. Student in Exercise Physiology, University of Virginia) Project: Effect of Single- and Multiple-Set Resistance Exercise on Postexercise Energy Expenditure (M.Ed. Thesis) Mr. Damon Swift, M.S., M.Ed.: 2003 to Present (M.Ed. and Ph.D. Student in Exercise Physiology, University of Virginia) Project: The association between Heart Rate Recovery and Endothelial Function in Abdominally Obese Women with the Metabolic Syndrome (M.Ed. Thesis) Project: The Effect of Aerobic Exercise Training on Endothelial Function in African American and Caucasian Women (Ph.D. Dissertation Project) Mr. Jason Blessinger, M.Ed.: 2005 to 2006 (M.Ed. Student in Exercise Physiology, University of Virginia) Project: Test-Retest Reliability of the Sensormedics VmaxST Portable Metabolic Measurement System (M.Ed. Thesis) Mr. Brandon Sawyer, M.Ed.: 2005 to 2006 (M.Ed. and Ph.D. Student in Exercise Physiology, University of Virginia) Project: Walking and Running Economy are Weakly Inversely Correlated to Maximal Oxygen Consumption in Healthy Males and Females (M.Ed. Thesis) Dr. Laura Tatpati M.D: 2006 to 2007 (clinical fellow from Reproductive Endocrinology) Project: The effect of branched chain amino acids on skeletal muscle mitochondrial function in skeletal muscle in aging adults Ms. Yiquan Sun: Jun 2011 to Aug 2011 (Summer Undergraduate Research Fellow) Project: The effect of modality on mixed muscle protein synthesis in young and elderly adults. Mr. Josh Fleming: May 2012 to Present (Exercise Physiology Graduate Assistant) Project: Lifestyle and Metabolic Predictors of Weight Regain following RYGB Ms. Meghan Fetterman: Jan 2013 to Aug 2013 (Exercise Physiology Graduate Intern) Project: Body composition assessment in Bariatric Patients Mr. Broc Wenrich: Jan 2013 to Present (Bucknell University Graduate Student) Project: NMR Spectroscopy-based Metabolomics and Type 2 Diabetes Mr. Matthew Miele: Sept 2013 to Present (Bucknell University Graduate Student) Project: NMR Spectroscopy-based Characterization of Human Serum ACADEMIC CAREER DEVELOPMENT: 1. University of Miami’s Leadership Summit; 1998 2. University of Virginia’s August Teaching Seminar; 2002 3. American College of Sports Medicine Teaching Symposium, 2003 4. NIH Grant Writing Workshop by David Morrison (Mayo Clinic), 2006 5. Biomedical Publications Workshop by David Morrison (Mayo Clinic), 2008 6. Leadership Principles in the 21st Century (Mayo Clinic), 2008 7. Annual Meeting for CTSA KL2, K12, and K30 Scholars (NIH), 2008 8. NIH Mock Study Section, 2008 9. Mitochondrial Molecular Biology and Pathology Workshop (NIH), 2008 10. Annual Midwest Consortium Meeting (Mayo Clinic), 2008 11. Presentation Skills Workshop (Mayo Clinic), 2008 12. Annual Meeting for ACRT/CTSA (NIH), 2009 13. Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis, 2010 14. Oroboros Oxygraph 2k High-Resolution Respirometry Training Workshop, 2012 15. Oroboros Oxygraph 2k Fluorometry Training Workshop, 2013 INSTITUTIONAL/DEPARTMENTAL ADMINISTRATIVE RESPONSIBILITIES, COMMITTEE MEMBERSHIPS, AND OTHER ACTIVITIES 2006-2012 2008-2012 Mayo Clinic Endocrine Research Unit; Ad hoc Reviewer Mayo Clinic Center for Translational Sciences Activities, Associate Member RESEARCH INTERESTS Integrative Physiology, Skeletal Muscle Metabolism, Skeletal Muscle Perfusion, Body Composition, Endocrine Response to Exercise, Aging, Obesity, Diabetes, and Sarcopenia RESEARCH GRANTS AWARDED CURRENT SUPPORT: Irving (PI) 9/15/2014-9/14/2015 1.2 months/year NIH/NIA Intramural Contract with Tamara Harris CHANGES IN OBJECTIVELY-MEASURED PHYSICAL ACTIVITY AND SEDENTARY BEHAVIOR AMONG BARIATRIC SURGERY PATENTS The aim of this study is to conduct a pilot study examining the practicality and validity of using accelerometers to capture physical activity and sedentary behavior among bariatric surgery patients in both a clinic-based setting and a free-living environment. Role: PI Not Assigned Still (PI) 1/1/2015-12/31/2020 Ethicon Impact of Bariatric Surgery on Total Joint Arthroplasty (Multi-Center Trial) 0.6 months/year The goals of this multicenter trial is to test the hypothesis that bariatric surgery prior to total joint arthroplasty will improve outcomes in patients with extreme obesity. We will compare long-term weight, physical function, mobility, indices of joint function, and quality of life in patients who receive bariatric surgery ~ 1 year before total joint arthroplasty vs. control subjects who receive total joint arthroplasty in the absence of pre-arthroplasty bariatric surgery. Role: CoI (Director of Physical Function Testing) SRC-L-37 Chang (PI) 10/01/2014-9/30/2015 0.4 months/year MORBID OBESITY, BARIATRIC SURGERY, AND KIDNEY FUNCTION: A PILOT STUDY The goals of the project are to identify and recruit a case-control cohort of morbidly obese patients to assess the effect of bariatric surgery on measured kidney function and kidney injury an to identify which filtration marker correlates bet with measured GFR in morbidly obese patients. Role: CoI 5P30DK072488-08 Shuldiner (PI) 9/1/2010-6/30/2015 0.6 months/year NIH/NIDDK MID-ATLANTIC NUTRITIONAL OBESITY RESEARCH CENTER (NORC): CLINICAL & TRANSLATIONAL RESEARCH (CTR) CORE CTR SATELLITE: GEISINGER MEDICAL CENTER, DANVILLE PA To foster multidisciplinary research approaches to understanding the impact of nutrition and obesity on risk for chronic disease and translating this knowledge into effective clinical treatments and prevention efforts. Role: Co-I SRC-L-15 Still (PI) 8/1/2013-7/31/2015 0.5 months/year Geisinger Clinical Research Fund THE COLLATERAL IMPACT OF BARIATRIC SURGERY ON FAMILIES This observational study will prospectively assess changes in bariatric surgery patients' cohabitating partners/spouses(N=40 dyads) pre and postoperatively (6 and 12 months) in: 1) weight (kg) and BMI; 2) dietary habits and eating behaviors;3) physical activity; 4) home food environments; 5) social support; 6) blood pressure and 7) serum lipoprotein levels. Changes in the weight and growth trajectories of patients' children will also be assessed. Role: Co-I 59-1950-9-963 Still (PI) 01/01/2014-12/31/2014 3.0 months/year USDA FEASIBILITY AND RELATIVE VALIDITY OF INTERNET-BASED DIETARY ASSESSMENT TOOLS AND THEIR RELATIONSHIP TO BODY COMPOSITION AND PHYSICAL FUNCTION IN RURAL PENNSYLVANIANS We propose a research project that compares a standard telephone 24-hour recall methodology collected using the Nutrition Data System for Research (NDSR) to an online Automated SelfAdministered 24-hour recall (ASA24). We also plan to administer an online version of our Diet Quality Screening Questionnaire (DQSQ). The proposed study will also provide assessment of the DQSQ based upon analysis of data collected using ASA24. We also plan to examine the relationships between our dietary assessment findings, and body composition and physical function. In addition, we intend to use this research as supporting preliminary data for a future effort to secure extramural funding to establish and follow a new (younger) GRAS-based cohort for dietary studies. Role: Co-I Not Assigned Irving (CoPI) 1/1/2015-12/31/2015 Bucknell-GHS Initiative NMR METABOLOMIC CHARACTERIZATION OF HUMAN SERUM 0.6 months/year The goals are to expand and complete method development to perform entire serum metabolic profiling onsite, including additional tests focusing on accuracy and precision, reproducibility, and statistical power and extend our model study of human diabetic states to build our expertise on realworld samples, to develop in-house expertise on statistical modeling of real-world metabolomic data, and to build a larger data set of future data mining. Role: CoPI COMPLETED SUPPORT: Not Assigned Irving (PI) 12/1/2014-11/30/2015 0.4 months/year NIH/NIDDK (Mid-Atlantic NORC) P&F (Declined to Move to LSU) QUANTITATIVE METABOLOMICS, TYPE 2 DIABETES, AND BARIATRIC SURGERY This pilot study will lead to a better characterization of serum metabolome of preoperative bariatric surgery patients with and without type 2 diabetes (T2D). Moreover, it will provide novel insight in to whether bariatric surgery can normalize the serum metabolome of T2D patients. Our long-term goal is to utilize quantitative metabolomics to enhance the ability to predict T2D remission in response to bariatric surgery and to predict those at risk for relapse of their T2D. Role: PI KL2 RR024151 Irving (PI-Trainee) Exercise Training and Individual Skeletal Muscle Protein Synthesis Rates in Aging Adults NIH/NCRR Role: PI (2007-2012) R01 AG09531-(Administrative Supplement) Nair (PI) Mechanism of Muscle Wasting in Aging Man NIH/AG Role: Co-Investigator (2007-Present) T32 AT07352 Eberhardt (PI) NIH/ NIDDK Endocrinology and Metabolism Training Grant NIH/NIDDK Role: Postdoctoral Fellow (2006-2007) Provost Research Grant Weltman (PI) University of Virginia Role: Research Coordinator (2001-2005) T32 AT00052 Taylor (PI) NIH/NCCAM Training Grant NIH/NCCAM Role: Predoctoral Fellow (2001-2005) UNFUNDED SUPPORT: Dairy Research Institute Irving (PI) 01/01/2015-12/31/2018 DASH PLUS DAIRY FOR OPTIMAL WHOLE NUTRITION TO TREAT DYNAPENIA Role: PI 3.6 months/year American Diabetes Association Irving (PI) 01/01/2014-12/31/2016 3 months/year IMPACT OF BARIATRIC SURGERY ON HEPATIC GLUCOSE AND APOLIPOPROTEIN METABOLISM IN TYPE 2 DIABETES Role: PI R24 Nadeau (PI), Still (Site PI) 07/01/2014-06/30/2019 Collaborative Interdisciplinary Science Team (R24) NIH/NIDDK IMMUNITY AND NASH: MECHANISMS AND THERAPEUTICS Role: Staff Scientist 1.2 months/year No assignment # ROLSTON (PI) 7/1/2013-6/30/2015 0.6 months/year Clinic Research Fund INTESTINAL PERMEABILITY IN NORMAL BMI, OBESE AND EXTREMELY OBESE INDIVIDUALS Role: CoI SRC-L-31 IRVING (PI) 12/1/2013-6/30/2015 0.6 months/year Clinic Research Fund IMPACT OF ROUX-EN-Y GASTRIC BYPASS ON SUBCUTANEOUS FAT MITOCHONDRIAL PHYSIOLOGY Role: PI 1R01HL112889-01Irving (PI) NIH/ NHLBI Skeletal Muscle Mitochondria in Heart Failure with Preserved Ejection Fraction NIH/NHLBI Role: PI (2012-2017) Priority Score: 35 Percentile: 38 PRESENTATIONS AT REGIONAL, NATIONAL AND INTERNATIONAL MEETINGS 1. Irving, BA, Anderson, SM, Weltman, JY, Watson-Winfield, DD, Frick, KI, Evans, WS, Veldhuis, JD, Weltman, A. Time of Exercise Initiation Does Not Affect Metabolic and Performance Responses During Acute Exercise. Presented at the American College of Sports Medicine Annual Meeting. San Francisco, California, May 28-31, 2003. 2. Henley, MO, Irving, BA, Gaesser, GA. Effect of Single- and Multiple-Set Resistance Exercise on Postexercise Energy Expenditure. Presented at the American College of Sports Medicine Annual Meeting. Indianapolis, Indiana, June 2-6, 2004. 3. Irving, BA, Rutkowski, JR, Davis, CK, Brock, D, Gaesser, G, Weltman, A. Ratings of Perceived Exertion and the Blood Lactate Response to Exercise: Borg vs. Omni. Presented at the American College of Sports Medicine Annual Meeting. Nashville, Tennessee, May 28-31, 2005. 4. Irving, BA, Swift, DL, Brock, DW, Davis, CK, Barrett, EJ, Gaesser, GA, Weltman, A. Heart Rate Recovery from Maximal Exercise is an Indicator of Endothelial Function in Women with the Metabolic Syndrome. Presented at the North American Association for the Study of Obesity Annual Meeting. Vancouver, British Columbia, October 15-19, 2005. 5. Brock, DW, Davis, CK, Irving, BA, Barrett, EJ, Weltman, A, Gaesser, GA. Differential Impact of HighCarbohydrate vs. Low-Carbohydrate Meals on Endothelial Function in Subjects with the Metabolic Syndrome. Presented at the North American Association for the Study of Obesity Annual Meeting. Vancouver, British Columbia, October 15-19, 2005. 6. Irving, BA, Brock, DW, Davis, CK, Barrett, EJ, Gaesser, GA, Weltman, A. Relationship among Cardiorespiratory Fitness (CRF), Physical Activity (PA), Abdominal Visceral Fat (AVF), Endothelial Function and Associated Risk Factors in Women with the Metabolic Syndrome (MS). Presented at the Southeast American College of Sports Medicine Annual Meeting. Charlotte, North Carolina, February 9-11, 2006. 7. Brock, DW, Irving, BA, Davis, CK, Barrett, EJ, Gaesser, GA, Weltman, A. Differential Impact of Chronic High-Carbohydrate vs. Low-Carbohydrate Diets on Endothelial Function in Adults with the Metabolic Syndrome. Presented at the Southeast American College of Sports Medicine Annual Meeting. Charlotte, North Carolina, February 9-11, 2006 & at the American College of Sports Medicine Annual Meeting. Denver, Colorado, May 31 - June 3, 2006. 8. Blessinger, JR, Sawyer, BJ, Irving, BA, Davis, CK, Weltman, A, Gaesser, GA. Test-Retest Reliability of the Sensormedics VmaxST Portable Metabolic Measurement System. Presented at the Southeast American College of Sports Medicine Annual Meeting. Charlotte, North Carolina, February 9-11, 2006. 9. Sawyer, BJ, Blessinger, JR, Irving, BA, Davis, CK, Weltman, A, Gaesser, GA. Walking and Running Economy are Weakly Inversely Correlated to Maximal Oxygen Consumption in Healthy Males and Females. Presented at the Southeast American College of Sports Medicine Annual Meeting. Charlotte, North Carolina, February 9-11, 2006 & at the American College of Sports Medicine Annual Meeting. Denver, Colorado, May 31 - June 3, 2006. 10. Irving, BA, Brock, DW, Davis, CK, Swift, DL, Barrett, EJ, Gaesser, GA, Weltman, A. Relationship among Fitness, Activity, Visceral Fat, and Associated Risk Factors in Women with the Metabolic Syndrome (MS) Presented at the American College of Sports Medicine Annual Meeting. Denver, Colorado, May 31 - June 3, 2006. 11. Gaesser, GA, Clark, BR, Parker, BE, Olowin, AB, Richardson, NT, Blessinger, JR, Sawyer, BJ, Davis, CK, Welk, GJ, Irving, BA. Validation of an Integrated Heart Rate/Physical Activity Monitor. Presented at the Southeast American College of Sports Medicine Annual Meeting. Charlotte, North Carolina, February 9-11, 2006 & at the American College of Sports Medicine Annual Meeting. Denver, Colorado, May 31 - June 3, 2006. 12. Davis, CK, Irving, BA, Brock, DW, Barrett, EJ, Gaesser, GA, Weltman, A. The Effects of Exercise Training on Microvascular Properties of Muscle Assessed by Contrast Ultrasound. Presented at the University of Virginia’s 18th Annual Children’s Hospital Research Symposium. Charlottesville, VA, May 11, 2006. 13. Irving, BA, Weltman, JY, Davis, CK, Swift, DL, Brock, DW, Barrett, EJ, Gaesser, GA, Weltman, A. Effects of Exercise Training Intensity on Abdominal Fat in Abdominally Obese Individuals with the Metabolic Syndrome. Presented at the American Diabetes Association Meeting. Washington, DC, June 8-13, 2006. 14. Irving, BA, Weltman, JY, Davis, CK, Swift, DL, Brock, DW, Patrie, J, Barrett, EJ, Gaesser, GA, Weltman, A. Effects of Exercise Training Intensity on Growth Hormone (GH) Secretion in Abdominally Obese Individuals with the Metabolic Syndrome (MS). Presented at the Endocrine Society Meeting. Boston, Massachusetts, June 24-27, 2006. 15. Weltman, J, Irving, B, Brock, D, Davis, C, Barrett, E, Gaesser, G, Weltman, A. Comparison of the NIH ImageJ and Slice-O-Matic Medical Imaging Software to Differentiate and Quantify Adipose and Skeletal Muscle Tissue from Computed Tomography (CT) Scans. Presented at the 10th International Congress of Obesity. Sydney, Australia, September 4-8, 2006. 16. Irving, B, Brock, D, Davis, C, Swift, D, Weltman, J, Patrie, J, Barrett, E, Gaesser, G, Weltman, A. Effects of Exercise Training Intensity on Markers of Inflammation in Abdominally Obese Individuals with the Metabolic Syndrome. Presented at the 10th International Congress of Obesity. Sydney, Australia, September 4-8, 2006. 17. Irving, BA, Brock, DW, Davis, CK, Swift, DL, Barrett, EJ, Gaesser, GA, Weltman, A. The Hypertriglyceridemic Waist (HTGW) Exacerbates Risk in Women with the Metabolic Syndrome. Presented at the North American Association for the Study of Obesity. Boston, Massachusetts, October 20-24, 2006. 18. Irving, BA, Swift, DL, Davis, CK, Barrett, EJ, Gaesser, GA, Weltman, A. Effects of Exercise Training Intensity on Cardiometabolic Risk in Women with the Metabolic Syndrome with or without Hypertension. Presented at the American College of Sports Medicine Meeting. New Orleans, LA, May 30 – June 2, 2007. 19. Davis, CK, Irving, BA, Brock, DW, Gaesser, GA, Barrett, EJ, Weltman, A. Exercise Training-Induced Changes in Skeletal Muscle Microvasculature Assessed by Contrast Enhanced Ultrasound. Presented at the American College of Sports Medicine Meeting. New Orleans, LA, May 30 – June 2, 2007. 20. Weltman, A., Irving, BA, Swift, DL, Davis, CK, Rodriguez, J, Frick, K, Barrett, EJ, Gaesser, GA. Exercise-Induced Weight Loss and Biological/Behavioral Compensation in Women with the Metabolic Syndrome (MS). Presented at the American College of Sports Medicine Meeting. New Orleans, LA, May 30 – June 2, 2007. 21. Tatpati, LL, Bigelow, M, Irving, BA, Kahl, J, Klaus, K, Short, KR, Nair, KS. Branched Chain Amino Acids Effect on Skeletal Muscle Mitochondrial ATP Production and Protein Metabolism - Interaction with Insulin and Age. Presented at the American Diabetes Association Meeting. Chicago, IL, June 22-26, 2007. 22. Raghavakaimal, S, Bigelow, M, Irving, BA, Chow, L, Asmann, Y, Kahl, J, Schimke, J, Nair, KS. Insulin Resistance and Altered Gene Transcript Levels in Asian Indians Compared to Americans of North European Origin. Presented at the American Diabetes Association Meeting. Chicago, IL, June 22-26, 2007. 23. Karakelides, H, Irving, BA, Bigelow, M, Short, KR, Kahl, J, Nair, KS. Adiponectin and Insulin Action Impact of Age, Body Composition, and Cardiorespiratory Fitness. Presented at the American Diabetes Association Meeting. Chicago, IL, June 22-26, 2007. 24. Irving, BA, Bigelow, M, Asmann, Y, Chow, L, Schimke, J, Raghavakaimal, S, Nair, KS. Investigation on Pathophysiology of Type 2 Diabetes Among Asian Indians. Presented at the Magnuson Congress for a Global Diabetes Alliance. Seattle, WA, October 22-23, 2007. 25. Srinivasan, M, Irving, B, Dhataryia, K, Klaus, K, Hartman, SJ, McConnell, JP, Nair, S. Effect of Dehydroepiandrosterone (DHEA) Replacement on Lipoprotein Profile in Hypoadrenal Women. American College of Cardiology. Chicago, IL, March 29-April 1, 2008. 26. Irving, BA, Bigelow, M, Asmann, Y, Chow, L, Coenen-Schimke, J, Klaus, KA, Guo, Z, Raghavakaimal, S, Nair, KS. Asian Indians have Enhanced Skeletal Muscle Mitochondrial Capacity to Produce ATP in Association with Severe Insulin-Resistance. Presented at the American Diabetes Association, San Francisco, CA, June 6-8, 2008. 27. Bhagra, S, Schimke, JM, Stump, C, Short, KR, Halvatsiotis, P, Irving, BA, Nair, KS. Insulin Modulates in vivo Myosin Heavy Chain (MHC) Isoform Transcription in Humans. Presented at the American Diabetes Association, San Francisco, CA, CA, June 6-8, 2008. 28. Jaleel, A, Karakelides, H, Klaus, K, Morse, D, Ward, L, Irving, B, Nair, KS. Alteration of Plasma Protein Synthesis by Insulin Treatment in Type 1 Diabetes. Presented at the American Diabetes Association, San Francisco, CA, June 6-8, 2008. 29. Sawyer, BJ, Blessinger, JR, Davis, SK, Irving, BA, Weltman, A, Gaesser, GA. The Slope of the VO2 Relationship During Walking and Running is Positively Correlate to VO2 Peak in Healthy Males and Females. To be Presented at the Southwest American College of Sports Medicine Annual Meeting, San Diego, CA, November 14-15, 2008. 30. Srinivasan, M, Irving, BA, Frye, RL, Brien, PO, Hartman, SJ, McConnell, JP, Nair, S. Impact of Long-Term Replacement with Dehydroepiandrosterone (DHEA) on Lipoprotein Profile in Elderly Males and Females. Presented at the Joint Conference of the 49th Cardiovascular Disease Epidemiology and Prevention-and-Nutrition, Physical Activity and Metabolism, Palm Harbor, FL, March 10-14, 2009. 31. Irving, BA, Rynders, CA, Angadi, SS, Weltman, NY, Gaesser, GA, Weltman, A. Abdominally Obese Women with the Metabolic Syndrome Have Higher Maximal Fat Oxidation Rates During Submaximal Treadmill Exercise Compared to Lean Women. Presented at the American College of Sports Medicine, Seattle, WA, May 27-May 31, 2009. 32. Irving, BA, Nair, KS, DHEA in Men and Women. Presented at the American Aging Association, Scottsdale, AZ, May 28-June 1, 2009. 33. Gaesser, GA, Angadi, S, Davis, C, Rodriguez, J, Irving, B, Patrie, J, Weltman, A, Barrett, EJ, Brock, D. Effects of a Low-Fat, High-Fiber Diet Compared with a Low-Carbohydrate Diet on Insulin Sensitivity and Endothelial Function in Adults with the Metabolic Syndrome. Presented at the American Dietetic Association, October 17-20, 2009. 34. Sawyer, BJ, Irving, BA, Patrie, JP, Angadi, S, Gaesser, GA. Percent Body Fat is Positively Correlated to Walking and Running Economy/Efficiency in Healthy Men and Women. Presented at the Southwest American College of Sports Medicine Annual Meeting, San Diego, CA, October 23-24, 2009. 35. Irving, BA. Skeletal Muscle Remodeling in Aging: Impact of Exercise Modality. International Symposium on Exercise. Mayo Clinic, Rochester, MN, Oct 14-15, 2010. 36. Lanza, IR, Irving, BA, Henderson, GC, Nair, KS. Mitochondrial Oxidative Capacity and Coupling: Effects of Aging and Exercise Training. Experimental Biology. Washington, DC, March 17, 2011. 37. Gaesser, G, Angadi, S, Weltman, N, Rodriguez, J, Patrie J, Barrett, E, Brock, D, Davis, C, Irving, B, Weltman, A. Impairment of Endothelial Function Despite Improvements in Traditional Lipid Markers in Low-Carbohydrate vs. High-Carbohydrate, High-Fiber Diet in Adults with Metabolic Syndrome. Washington, DC, March 17, 2011. 38. Irving, BA, Lanza, IR, Henderson, GC, Weymiller, A, Schimke, J, Morse, D, Nair, KS. Effect of Exercise Training Modality on Skeletal Muscle Mitochondrial Biogenesis in Young and Older Adults. Experimental Biology. Washington, DC, March 17, 2011. 39. Irving, BA, Lanza, IR, Henderson, GC, Weymiller, A, Schimke, J, Morse, D, Nair, KS. Effect of Exercise Training Modality on Skeletal Muscle mRNA Abundance in Young and Older Adults. American College of Sports Medicine. Denver, CO, Jun 1-4, 2011. 40. Sawyer, BJ, Irving, BA, Patrie, J, Angadi, S, Gaesser, GA. Percent Body Fat is Positively Correlated to Walking and Running Economy/Efficiency in Healthy Adults. American College of Sports Medicine. Denver, CO, Jun 1-4, 2011. 41. Weymiller, AJ, Irving, BA, Carter, RE, Persson, M, Tatpati, L, Bhagra, S, Soop, M, Nair, KS. Metformin and Pioglitazone Altered Plasma Amino Acid Metabolites – Potential Biological Markers of Insulin Sensitivity. American Diabetes Association. San Diego, CA, Jun 24-28, 2011. 42. Irving, BA, Weymiller, AJ, Syed, H, Karakelides, H, Soop, M, Carter, RE, Nair, KS. Amino Acid Metabolites and Insulin Resistance in Human. American Diabetes Association. San Diego, CA, Jun 24-28, 2011. 43. Irving, BA, Lanza, IR, Dalla Man, C, Henderson, GC, Nelson, R, Miles, J, Cobelli, C, Nair KS. Effect of Age, Sex, Mitochondrial Function, and Exercise Training on Insulin Sensitivity, Beta-Cell Responsivity, and Fatty Acids in Response to a Mixed-Meal. European Association for the Study of Diabetes. Lisbon, Portugal, Sept 12-16, 2011. 44. Almandoz, J, Howell, J, Grothe, K, Irving, B, ES, Nelson, R, Miles, J. Strategy for Weight Loss Through Multidisciplinary Lifestyle Approach Focusing on Calorie Deficit in Obese Patients with Type 2 Diabetes. To be presented at the American Association of Clinical Endocrinologist, Philadelphia, PA, May 23 – May 27, 2012. 45. Clasey, JL, Bradley, KD, Bradley, JW, Irving, BA, Crofford, LJ. A New BIA Equation Estimating the Body Composition of Young Non-Hispanic Black Women. American College of Sports Medicine, San Francisco, CA, May 29 – Jun 2, 2012. 46. Almandoz, J, ES, Irving, B, Nelson, R, Miles, J. Relationship between Body Fat Depots and Spillover of Fatty Acids from Chylomicrons in Subjects with Type 2 Diabetes: Effect of Weight Loss. American Diabetes Association, Philadelphia, PA, Jun 8 – May 12, 2012. 47. Clasey, JL, Bradley, KD, Bradley, JW, Irving, BA, Crofford, LJ. A Comparison of Body Composition Assessment Methods in Young Non-Hispanic Black Women. The Obesity Society, San Antonio, TX, Sept 20 – Sept 24, 2012. 48. Irving, BA, Roesch, S, Kane, C, Styer, A, Argyropoulos, A. AgRP Deficient Female Mice have Increased Body Weight and Hypothalamic Mitochondrial Oxidative Capacity. Bucknell Geisinger Research Initiative. Bucknell University, Lewisburg, PA. November 28, 2012. 49. Irving, BA, Roesch, S, Kane, C, Styer, A, Argyropoulos, A. AgRP Deficient Female Mice have Increased Body Weight and Hypothalamic Mitochondrial Oxidative Capacity. IOC72 O2k Workshop. Schroecken, Austria. December 5-10, 2012. 50. Irving, BA, Roesch, S, Kane, C, Styer, A, Argyropoulos, A. AgRP Deficient Female but not Male Mice have Hypothalamic Mitochondrial Oxidative Capacity. Endocrine Society Annual Meeting. San Francisco, Ca. Jun 15-18, 2013. 51. Irving, BA, Stahl, R, Kane, C, Chernousov, M, Argyropoulos, A, Carey, D. Sex Differences in Murine Mitochondrial Oxidative Capacity following 24 week High-Fat Diet. 9th Conference of Mitochondrial Physiology (MIP2013): Comparative Mitochondrial Physiology. Oborgurgl, Austria. Sept 23-27, 2013. 52. Clasey, JL, Bradley, KD, Bradley, JW, Irving, BA, Crofford, LJ. A New BIA Equation Estimating the Fat-Free Mass of Young Non-Hispanic Black Women. Obesity Week, Atlanta, GA, Nov 11 – Nov 16, 2013. 53. Fleming, JJ, Rawson, ES, Still, CS, Wood, GC, Benotti, PN, Seiler, JL, McConnel, TR, Irving, BA. Comparison of Methods for Estimating Resting Energy Expenditure in Post-Bariatric Surgery Patients. Mid-Atlantic American College of Sports Medicine. Harrisburg, PA. Nov 1-2, 2013. 54. Wenrich, BR, Irving, BA, Rovnyak, D. Investigation into NMR Metabolomic Characterization of Human Type II Diabetic States. Experimental Nuclear Magnetic Resonance Conference. Boston, MA. Mar 23-28, 2014. 55. Fleming, JJ, Rawson, ES, Still, CS, Wood, GC, Benotti, PN, Seiler, JL, McConnel, TR, Irving, BA. Comparison of Methods for Estimating Resting Energy Expenditure in Post-Bariatric Surgery Patients. American College of Sports Medicine. Orlando, FL. May 28-31, 2014. 56. Konopka, AR, Asante, A, Amols, MH, Lanza, IR, Johnson, ML, Robinson, MM, Irving, BA, Nair, KS. Aerobic Exercise Training Improves Insulin Sensitivity and Skeletal Muscle Mitochondrial Energetics in Women with Polysistyic Ovary Syndrome. American Diabetes Association. San Francisco, CA, Jun 13-17, 2014. 57. Alaparthi, R, Miele, M, Wenrich, B, Irving, B, Rovnayk, D. Method Validation of NMR Metabolite Measurements. Susquehanna Valley Undergraduate Research Symposium. Danville, PA. Aug 5, 2014. 58. Wood, GC, Benotti, P, Argyropoulos, GA, Irving, BA, Rolston, DD, Still, CD, Gerhard, GS. A Combined Clinical and Genetic Classification Score for Nonalcoholic Fatty Liver Disease (NAFLD) in Patients with Morbid Obesity. Obesity Week. Boston, MA. November 3-7, 2014. 59. Rolston, DDK, Wood GC, Ellapan, B, Benotti, PN, Argyropoulos, GA, Deshpande, A, Irving, B, Gerhard, GS, Still, CD. Ion-dependent Transporter Expression in Human Jejunum is Influenced by Body Mass Index (BMI). Obesity Week. Boston, MA. November 3-7, 2014. 60. Fleming, J, Rawson, E, Irving, B, Benotti, P, McConnell, T, Seiler, J, Wood, GC, Still, CD. Physical Inactivity: A Potential Correlate of Weight Regain After Bariatric Surgery. Obesity Week. Boston, MA. November 3-7, 2014. BIBLIOGRAPHY REFEREED PUBLICATIONS: 1. Irving, BA, Patrie, JT, Anderson, SM, Watson-Winfield, DD, Frick, KI, Evans, WS, Veldhuis, JD, Weltman, A. The Effects of Time Following Growth Hormone (GH) Administration on Metabolic and Performance Measures During Acute Exercise. J Cli Endo Met. 89 (9): 4298-4305, SEP 2004. PMID: 15328062. 2. Irving, BA, Rutkowski, JR, Davis, CK, Brock, DW, Gaesser, GA, Weltman, A. Comparison of BorgOMNI RPE as Markers of the Blood Lactate Response to Exercise. Med Sci Sports Exerci. 38 (7): 1348-1352, JUL 2006. PMID: 16826034. 3. Irving BA, Davis, CK, Swift, D, Brock, DW, Barrett, EJ, Gaesser, GA, Weltman A. Effects Of Exercise Training Intensity on Abdominal Visceral Fat and the Cardiometabolic Risk Profile in Abdominally Obese Individuals with the Metabolic Syndrome. (Invited Paper) Physical Activity and Obesity (A.P. Hills, N.A. King, N.M. Byrne eds) Smith-Gordon Nishimura, London, 2006, 81-90. 4. Brock, DW, Davis, CK, Irving, BA, Rodriguez, J, Barrett, EJ, Weltman, A, Taylor, AG, Gaesser, GA. A High-Carbohydrate, High-Fiber Meal Improves Endothelial Function in Adults with the Metabolic Syndrome. Diabetes Care. 29 (10): 2313-2315, OCT 2006. PMID: 17003313. 5. Irving, BA, Weltman, JY, Brock, DW, Davis, CK, Barrett, EJ, Gaesser, GA, Weltman, A. NIH ImageJ and Slice-O-Matic Computed Tomography Imaging Software to Quantify Soft Tissue. Obesity.15 (2):370-376, FEB 2007. PMID: 17299110. 6. Irving BA, Davis, CK, Brock, DW, Weltman, JY, Swift, D, Barrett, EJ, Gaesser, GA, Weltman A. The Metabolic Syndrome, Hypertriglyceridimic Waist, and Cardiometabolic Risk Factor Profile in Obese Women. Obesity and Metabolism. 3 (2):50-57, JUN 2007. 7. Swift, DL, Irving, BA, Brock, DW, Davis, CK, Barrett, EJ, Gaesser, GA, Weltman, A. The association between Heart Rate Recovery and Endothelial Function in Abdominally Obese Women with the Metabolic Syndrome. Obesity and Metabolism. 3 (3):101-105, SEP 2007. 8. Irving, BA, Nair, KS. Aging and Diabetes: Mitochondrial Dysfunction. Curr Diab Rep. 7 (4):249-51, AUG 2007. PMID: 17686399. 9. Irving, BA*, Igwebuike, A*, Bigelow, ML, Short, KR, McConnell, Nair, KS. Lack of DHEA Effect on a Combined Endurance and Resistance Exercise Program in Postmenopausal Women. J Cli Endo Met. 93 (2):534-538, FEB 2008. PMID: 18029465 10. Nair, KS, Bigelow, ML, Asmann, YW, Chow, L, Coenen-Schimke, JM, Kahl, JC, Guo, ZK, Sreekumar, R, Irving, BA. Asian Indians have Enhanced Skeletal Muscle Mitochondrial Capacity to Produce ATP in Association with Severe Insulin-Resistance. Diabetes. 57 (9):1166-1175, MAY 2008. PMID: 18285554. 11. Irving BA, Davis, CK, Swift, D, Brock, DW, Barrett, EJ, Gaesser, GA, Weltman A. Effects Of Exercise Training Intensity on Abdominal Visceral Fat and Body Composition. Med Sci Sports Exerci. 40 (11): 1863-1872, NOV 2008. PMID: 18845966 12. Blessinger, JR, Sawyer, BJ, Davis, CK, Irving, BA, Weltman, A, Gaesser, GA. Reliability of the VmaxST Portable Metabolic Measurement System. Int J Sports Med. JAN 2009. PMID: 18651368. 13. Allmand, MC, Irving, BA, Asmann, YW, Klaus, KA, Tatpati, L, Coddington, CC, Nair, KS. The Effects of Testosterone on Insulin Stimulated IRS 1 Ser636/639 Phosphorylation in Rat Skeletal Muscle Primary Culture. PLos One. 4 (1): e4274. doi.1371/journal.pone.0004274. JAN 2009. PMID: 19169352. PMCID: 262543. 14. Srinivasan, M, Irving, BA, Dhataryia, K, Klaus, K, Hartman, SJ, McConnell, JP, Nair, S. Does Dehydroepiandrosterone Replacement have an effect on Lipoprotein Profile in Hypoadrenal Women? J Cli Endo Met. 2009 MAR 94 (3): 761-764. PMID: 19066301. PMCID 2681274 15. Irving BA, Weltman, JY, Patrie, JT, Davis, CK, Swift, D, Brock, DW, Barrett, EJ, Gaesser, GA, Weltman A. Effects Of Exercise Training Intensity on Nocturnal Growth Hormone Secretion in Obese Adults with the Metabolic Syndrome. J Cli Endo Met. 2009 Jun;94(6):1979-86. [Epub 2009 MAR 24]. PMID: 19318453. 16. Henderson, GC, Irving, BA, Nair, KS. Invited Editorial: Potential Application of Essential Amino Acid Supplementation to Treat Sarcopenia in Elderly People. J Cli Endo Met. 2009 MAY 94 (5):15241526. PMID: 1920276. 17. Jaleel, A, Klaus, KA, Morse, DM, Karakelides, H, Ward, LE, Irving, BA, Nair, KS. Differential Effects of Insulin Deprivation and Systemic Insulin Treatment on Plasma Protein Synthesis in Type 1 Diabetic People. Am J Physiol Endocrinol Metab. 2009 OCT 297 (4): E889-E897. [Epub 2009 Aug 4]. PMID: 19654285. 18. Karakelides, H, Irving, BA, Short, KR, O’Brien, P, Nair, KS. Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function. Diabetes. 2010 Jan;59(1):89-97. [Epub 2009 Oct 15]. PMID: 19833885. 19. Irving, BA*, Tatpati, LL*, Tom, A, Bigelow, ML, Klaus, K, Short, KR, Nair, KS. The Effect of Branched Chain Amino Acids on Skeletal Muscle Mitochondrial Function in Aging Adults. J Cli Endo Met. 2010 Feb;95(2):894-902. [Epub 2009 Dec 18]. PMID: 20022987. 20. Irving, BA*, Srinivasan, M*, Frye, RL, O’Brien, P, Hartmann, S, McConnell, JP, Nair, S. Impact of Long-Term Replacement with Dehydroepiandrosterone or Testosterone in Elderly Men and Dehydroepiandrosterone in Elderly Women on Lipoprotein Profile. J Cli Endo Met. 2010 Apr;95(4):1617-25. [Epub 2010 Feb 5.]. PMID: 20139233. 21. Sawyer, BJ, Blessinger, JR, Irving, BA, Weltman, A, Patrie, JP, Gaesser, GA. Walking and Running Economy: Inverse association with Peak Oxygen Uptake. Med Sci Sports Exerci. 2010 Nov;42(11):2122-7 [Epub 2010 Mar 25]. PMID: 20351592 22. Brock, DW, Irving, BA, Gower, B, Hunter, GR. Differences Emerge in Visceral Adipose Tissue Accumulation After Selection for Innate Cardiovascular Fitness. Int J Obes (Lond). 2011 Feb;35(2):309-12. [Epub 2010 Jul 20]. PMID: 20644556 23. Ranganath M, Irving, BA, Unni, US, Briggs, WM, Nair, KS, Quon, MJ, Kurpad, AV. Limited Predictive Ability of Surrogate Indices of Insulin Sensitivity/Resistance in Asian Indian Men. Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E1106-12. [Epub 2010 Oct 13]. PMID: 20943755 24. Rostambeigi, N, Lanza, IR, Dzeja, P, Deeds, MC, Irving, BA, Reddi, HC, Madde, P, Zhang, S, Asmann, YW, Anderson JM, Schimke, JM, Nair, KS, Eberhardt, NL, Kudva, YC. Unique Cellular and Mitochondrial Defects Mediate FK506-induced Islet β-cell Dysfunction. Transplantation. 2011 Mar 27;91(6):615-23. [Epub 2010 Dec 31]. PMID: 21200364 25. Irving, BA, Nair, KS, Srinivasan, M. Effects of Insulin Sensitivity, Body Composition, and Fitness on Lipoprotein Particle Sizes and Concentrations Determined by Nuclear Magnetic Resonance. J Cli Endo Met.. 2011 Apr;96(4):E713-8. [Epub 2011 Jan 26]. PMID: 21270325 26. Nair, KS, Irving, BA, Lanza, IR. Can Dietary Nitrates Enhance the Efficiency of Mitochondria? Cell Metab. 2011 Feb 2;13(2):117-8. PMID: 21284976 27. Irving, BA, Short, KR, Nair, KS. Stump, C. Nine Days of Aerobic Interval Training Improves Mitochondrial Function but not Insulin Action in Offspring of Type 2 Diabetics. J Clin Endo Met. Jul;96(7):E1137-41. [Epub 2011 Apr 20]. PMID: 21508128. 28. Irving, BA, Robinson, MM, Nair, KS. Age Effect on Myocellular Remodeling: Response to Exercise and Nutrition in Humans. Ageing Res Rev. 2012 Jul; 11 (3): 374089. [Epub 2011 Nov 7]. PMID 22085885. 29. Di Camillo, B, Irving, BA, Schimke, J, Sanavia, T, Toffolo, G, Cobelli, C, Nair, KS. Function-Based Discovery of Significant Transcriptional Temporal Patterns in Insulin Stimulated Muscle Cells. Plos One. 2012; 7(3):e32391. [Epub 2012 Mar 1]. PMID: 22396763. 30. Grubina, R, Irving, BA, Soop, M, Srinivasan, M, Tatpati, L, Chow, L, Weymiller, A, Carter, RE, Nair, KS. Insulin Sensitizer Therapy Improves Atherothrombotic and Inflammatory Profiles Associated with Insulin Resistance – A Randomized, Controlled Trial. Mayo Clinic Proceedings. Mayo Clinic Proc. 2012 Jun;87 (6): 561-70. PMID: 22677076. 31. Irving, BA*, Short, KR*, Basu, A, Johnson, M, Nair, KS. Basu, R. Effects of Type 2 Diabetes and Insulin on Whole Body, Splanchnic, and Leg Protein Metabolism. J Clin Endo Met. 2012 Dec;97(12):4733-41. doi: 10.1210/jc.2012-2533. Epub 2012 Oct 2. PMID: 23032060. 32. Ruas, JL, White, JP, Brannan, KT, Harrison, B, Greene, NP, Wu, J, Kleiner, S, Estall, JL, Irving, BA, Lanza, IR, Rasbach, KA, Okutsu, M, Nair, KS. Yan, Z, Leinwand, L, Spiegelman, BM. A Novel PGC1-α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy. Cell. 2012 Dec 7;151(6):1319-31. doi: 10.1016/j.cell.2012.10.050. PMID: 23217713. 33. Almandoz, JP, Singh, E, Howell, LA, Grothe, K, Vlanzy, DT, Smailovic, A. Irving, BA, Nelson, RH, Miles, JM. Spillover of Fatty Acids during Dietary Fat Storage in Type 2 Diabetes: Relationship to Body Fat Depots and Effects of Weight Loss. Diabetes. 2013 Jun;62(6):1897-903. doi: 10.2337/db12-1407. Epub 2013 Jan 24. 34. Still CD, Wood GC, Benotti P, Petrick AT, Gabrielsen J, Strodel WE, Ibele A, Seiler J, Irving BA, Celaya MP, Blackstone R, Gerhard GS, Argyropoulos G. 2013 Preoperative Prediction of Type 2 Diabetes Remission after Roux-en-Y Gastric Bypass surgery: a retrospective cohort study. The Lancet Diabetes & Endocrinology. 2014 Jan;2(1):38-45. 35. Irving, BA, Still CD, Argyropolous, GA. Does IRISIN have a BRITE future as human therapeutic agent in humans? Curr Obes Rep. 2014; 3: 235-241. 36. Hayes, S, Napolitano, M, Lent, MR, Wood, C, Gerhard GS, Irving, BA, Argyropolous, G, Foster, GD, Still, CD. The Effect of Insurance Status on Pre- and Post-operative Bariatric Surgery Outcomes. Obesity Surgery. 37. Johnson, ML, Irving, BA, Lanza, IR, Vendelbo, MH, Konopka, AR, Robinson, MM, Henderson, GC, Klaus, KA, Morse, DM, Heppelmann, C, Bergen, HB, 3rd,Dasari, S, Schimke, JM, Jakaitis, DR, Nair, KS. Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging. Journal of Gerontology: Biological Sciences. 38. Huseini, M, Wood, GC, Seiler, J, Arygyropoulos, G, Irving, BA, Gerhard, GS, Benotti, P, Still, S, Rolston, DDK. Gastrointestinal Symptoms in Morbid Obesity. Frontiers in MEDICINE: Gastroenterology. Online. 39. Irving, BA, Carter, RE, Soop, M, Weymiller, A, Syed, H, Karakelides, H, Bhagra, S. Short, KR, Tatpati, L, Barazzoni, R, Nair, KS. Effect of Insulin Sensitizer Therapy on Amino Acids and their Metabolites. Metabolism. 2015 Jan 22. pii: S0026-0495(15)00023-2. doi: 10.1016/j.metabol.2015.01.008. [Epub ahead of print] 40. Irving, BA, Lanza, IR, Henderson, GH, Spiegelman, B, Nair, KS. Combined Training Enhances Skeletal Muscle Mitochondrial Oxidative Capacity Independent of Age. J Cli Endo Met. Jan 19:jc20143081. [Epub ahead of print] 41. Konopka, AR, Asante, A, Lanza, IR, Robinson, MM, Johnson, ML, Dalla Man, C, Cobelli, C, Amols, MH, Irving, BA, Nair, KS. Defects in Mitochondrial Efficiency and H2O2 Emissions in Obese Women are Restored to a Lean Phenotype with Aerobic Exercise Training. Diabetes. 2015 Jan 20. pii: db141701. [Epub ahead of print] 42. Ford, GC, Hines, KM, Klaus, K, Irving, BA, Ford, BL, Johnson, KL, Lanza, IR, Nair, KS. Application of High-Resolution Mass Spectrometry to Measure Low Abundance Isotope Enrichment in Individual Muscle Proteins. Anal Bional Chem. OTHER PUBLICATIONS: 1. Parker, EB, Clark, BR, Richardson, NT, Olowin, AB, Gaesser, GA, Irving, BA. A Low-Cost, HighPerformance Physical Activity Monitor (PAM). Final Report. Department of Education, March 31, 2004. (Contract No. ED-01-CO-0123) 2. Irving, BA. Dissertation: Impact of Exercise Intensity on Abdominal Visceral Fat (AVF) and Risk Factors Associated with the Metabolic Syndrome. Advisors: Arthur Weltman, Glenn Gaesser, Eugene Barrett, Ann Gill Taylor. University of Virginia. March 2006. PUBLICATIONS IN REVIEW: PUBLICATIONS IN PREPARATION: 1. Irving, BA, Rolston, DDK, Wood GC, Ellapan, B, Benotti, PN, Argyropoulos, GA, Deshpande, A, Lent, MR, Gerhard, GS, Still, CD. Ion-dependent Transporter Expression in Human Jejunum in Relation to Body Mass Index in Bariatric Surgery. International Journal of Obesity. ANCILLARY PROJECTS: 1. McArdle, WD, Katch, FI, Katch, VL. Essentials of Exercise Physiology. PowerPoint Slide Show (Prepared by Irving, BA). June 1, 2005.