The Health of the Grampian Population: A Review of Current and Future Health Challenges Original report prepared by Dr Lesley Wilkie and Dr Catriona Hughes October 2009 Updated by Dr Emmanuel Okpo 2010 Contents Foreward ................................................................................................................... 8 Childhood ................................................................................................................ 9 Children in Grampian ................................................................................................ 9 Births ....................................................................................................................... 10 Health of newborns and young children................................................................... 11 Life expectancy at birth ........................................................................................... 15 Ill health in childhood ............................................................................................... 17 Preventing illness in childhood ................................................................................ 21 Immunisation ........................................................................................................... 21 Dental health ........................................................................................................... 23 Lifestyle issues in later childhood ............................................................................ 24 Mortality in infants and childhood ............................................................................ 29 Working age population........................................................................................ 31 Mortality .................................................................................................................. 31 Morbidity ................................................................................................................. 34 Behavioural risk factors ........................................................................................... 36 Screening in adults .................................................................................................. 39 Infectious diseases .................................................................................................. 41 Elderly population .................................................................................................... 43 Mortality .................................................................................................................. 45 Morbidity ................................................................................................................. 45 Preventing ill health ................................................................................................. 48 Diseases of significant concern ........................................................................... 51 Cancer .................................................................................................................... 51 Coronary Heart Disease (CHD) ............................................................................... 52 Stroke...................................................................................................................... 56 Chronic Obstructive Pulmonary Disease (COPD) .................................................... 59 Chronic Kidney Disease (CKD) ............................................................................... 60 Diabetes .................................................................................................................. 61 Mental health........................................................................................................... 61 Protecting the health of the population ............................................................... 63 Outbreaks of gastrointestinal infections ................................................................... 65 Immunisation and vaccine preventable diseases..................................................... 65 Description of the UK immunisation programme ...................................................... 66 Vaccine update results - overview of 2009/2010 ..................................................... 66 Primary immunisation uptake rate by deprivation .................................................... 67 Uptake of HPV vaccine ........................................................................................... 68 Tuberculosis (TB) .................................................................................................... 71 Pandemic influenza ................................................................................................. 71 References ............................................................................................................. 72 2 List of Figures and Tables Figure 1: percentage of children aged between 0-14 years in Grampian by local council area (based on mid 2008 population estimates) .......................... 9 Figure 2: Projected percentage change in population aged 0-15 (2006 based), by Grampian Council Areas 2006-2031 ......................................................... 10 Figure 3: Number of live births per year by council area4 .............................. 11 Figure 4: Smoking at Booking Grampian 2000-2006 ..................................... 12 Figure 5: Trends in percentage of women smoking during pregnancy in Grampian 1995-2008 ..................................................................................... 12 Figure 6: Percentage of mothers smoking during pregnancy by CHP 19952008 ............................................................................................................... 13 Table 1: Proportion of mothers in Grampian breastfeeding at 6 weeks 2006/2007. ..................................................................................................... 13 Table 2: Percentage low weight live births weight Babies in Grampian & CHPs (Singleton Births) 3 year averages 2005/06–2007/08. ................................... 14 Figure 7: Average BMI by gender and year15................................................. 14 Figure 8: Life expectancy in Grampian compared to Scotland (1981-2007) .. 16 Figure 9: Life expectancy at birth for Aberdeen City, Aberdeenshire and Moray (1981-2007) ................................................................................................... 16 Table 3: Life expectancy at birth (2005-2007)10 ............................................. 17 Figure 10: Causes of elective admissions in children in Grampian 2007/08 7. 18 Figure 11: Causes of emergency admission in children in Grampian 2007/08 7 ....................................................................................................................... 19 Table 4: Rates of unintentional injuries in the home, 3 year average crude rate 2004-200617 ................................................................................................... 19 Table 5: Emergency hospital admissions as a result of an unintentional injury in Children aged under 15 in Grampian NHS Community Health Partnership, and Scotland year ending 31 March 2009 ..................................................... 20 Table 6: Unintentional injury in children, 2007/087 ......................................... 20 Table 7: Uptake rates-Percentage completing primary course by 24 months of age (1 April 2009 to 31 Marcn 2010) in Grampian, Grampian CHP areas and Scotland ......................................................................................................... 21 3 Table 8: Percentage completing primary course by 5 years of age (1 April 2009 to 31 March 2010) in Grampian, Grampian CHP areas and Scotland .. 22 Figure 12: Percentage of Primary 1 children with no decay. .......................... 23 Figure 13: Percentage of school-aged children who have ever had a proper alcoholic drink in Grampian 2006 compared with 2002 .................................. 24 Figure 14: Percentage of school-aged children who are regular smokers in Grampian 2006 compared with 2002 ............................................................. 25 Figure 15: Percentage of school-aged children who have used drugs in the month prior to the survey ............................................................................... 26 Figure 16: Teenage Pregnancy rates per 1000 women in Grampian and Scotland 1994-2007 ....................................................................................... 27 Figure 17: Teenage pregnancy in Grampian by age group and deprivation quintile, 2007.................................................................................................. 27 Table 9: Stillbirth and infant mortality rates per 1000 live births 3 year averages 2006-20085 ..................................................................................... 29 Figure 18: Deaths in children under 15 years of age by SIMD14 .................... 30 Table 10: Projected percentage changes in population (2006-based), by council areas and Grampian selected years .................................................. 31 Figure 19: Main causes of death in all age groups in Grampian, 2008. ......... 32 Table 11: Most frequent causes of death in Scotland by age group .............. 33 Figure 20: Main causes of premature death in Grampian, 2008. ................... 33 Table 12: Percentage of population reporting limiting long-term illness, 2001 census17 ......................................................................................................... 34 Table 13: Incidence rates of long term condition discharges from hospital per 100,000 Population, Grampian and Scotland 2008/2009 ............................... 34 Table 14: Incidences rates of main diagnosis discharges from hospital per 100,000 population by Financial Year in Grampian (all ages) ........................ 35 Table 15: QOF prevalence data per 100 registered patients31....................... 36 Figure 21: Percentage of population smoking by SIMD quintile, Scotland 200734. ........................................................................................................... 37 Table 16: Estimated percentage of smokers in the adult population by age and sex, 2003/0433................................................................................................ 37 4 Figure 22: Estimated levels of harmful drinking in the adult Scottish population by type of harmful drinking36. ......................................................................... 38 Figure 23: Percentage of selected Grampian population groups taking the recommended level of physical activity per week. ......................................... 39 Figure 24: Persons in Grampian reported to be hepatitis C antibody positive 1999 to 31 March 200943 ............................................................................... 41 Figure 25: HIV incidence rate by year, Grampian and Scotland44.................. 42 Figure 26: Elderly population of the North east hospital region (1959-2008) . 43 Table 17: Projected population aged 65 and over (persons) 2006-2031 in thousands ...................................................................................................... 44 Figure 27: Population projections for the 75 and over age group in Grampian 2 ....................................................................................................................... 44 Figure 28: Self-perception of health by age group46 ...................................... 45 Figure 29: Trend of Admission Rates per 100,000 Population of All Emergency Admissions for Patients Aged 65+ by Financial Year, Scotland, Grampian and CHP........................................................................................ 46 Figure 30: Admission Rates per 100,000 Population of All Emergency Admissions for Patients Aged 65+ by 5 year age group Grampian 2008/2009 ....................................................................................................................... 47 Table 18: NHS Grampian Staphylococcus aureus bacteraemia rates January 2006-June 2009 ............................................................................................. 48 Table 19: Numbers of cases and rates of CDAD in patients 65 years and older 51 .................................................................................................................... 49 Figure 31: Deaths associated with CDAD in Grampian by year52 .................. 49 Table 20: Projected number of cases of cancer in Grampian54...................... 51 Figure 32: Projected cases per 5 year period by ICD code for Grampian 54 ... 51 Figure 33: European age-standardised incidence (2001-2005) and mortality (2003-2007) rates for cancer in Scotland, by SIMD 2006 deprivation quintile 57. ....................................................................................................................... 52 Figure 34: CHD mortality rates among under 75 year olds in the most deprived 15% areas (SIMD 2006); rate per 100,000 European agestandardised (EASR) 3 year rolling averages 1998-2008 .............................. 53 Figure 35: Incidence of CHD (from first hospital admission) .......................... 54 5 Figure 36: Trend, Age-sex standardised incidence rate from CHD (Standard European population) per 100, 000 population. CHP, Grampian and Scotland 2000-2009 (all age groups) ............................................................................ 54 Figure 37: Trend, Age-Sex standardised mortality rate from CHD (Standard European Population) per 100, 000 population. CHP, Grampian and Scotland 1999-2008 (all age groups) ............................................................................ 55 Figure 38: Trend, Age-Sex Standardised Incidence rate of cerebrovascular disease (by first hospital admission) Grampian, CHP area and Scotland 20002009 66............................................................................................................ 56 Figure 39: Trend, Age-sex standardised mortality rates from stroke per 100,000 population (Grampian, CHP, Scotland) 2000-2009. ......................... 57 Figure 40: Standardised rates (%) of patients surviving for 30 days after an emergency admission for Stroke in NHS Grampian Hospitals 1998-200765 .. 58 Figure 41: Age-sex standardised mortality rates (under 75) from stroke per 100,000 population in Grampian 2000-2009: Progress against targets ......... 58 Table 21: QOF Prevalence Estimates of COPD in Grampian and CHP ........ 59 Table 22 : Episodes of Care as a Consequence of COPD & Bronchiectasis Grampian Residents ...................................................................................... 60 Figure 42: Rates of neurotic disorder by subcategory71 ................................. 62 Table 23: Admissions to mental illness specialities in Grampian hospitals by type of admission 2007/2008 ......................................................................... 62 Figure 43: E Coli o157 2005 to 2010 ............................................................ 63 Table 24: Number of cases of reported and notified communicable disease in Grampian in 2005-2009 ................................................................................. 64 Table 25: Number of outbreaks of gastrointestinal infection by date reported to Health Protection Scotland 2005-2009 .......................................................... 65 Table 26: Location of outbreaks of Norovirus infection reported by NHS Grampian ....................................................................................................... 65 Table 27: Uptake of Diphtheria, Tetanus, Pertussis, Polio and Hib by 12 months of age in Grampian 1 April 2009 to 31 March 2010 ........................... 66 Table 28: Uptake of Diphtheria, Tetanus, Pertussis, Polio and Hib by 24 months of age in Grampian by CHP area, 1 April 2009 to 31 March 2010 .... 67 Table 29: Uptake of Diphtheria, Tetanus, Pertussis, Polio and Hib by 5 years of age in Grampian by CHP area, 1 April 2009 to 31 March 2010 ................. 67 6 Figure 44: Uptake of immunisation by deprivation ......................................... 68 Figure 45: Uptake of HPV Immunisation for Girls in S2 in Grampian by CHP Year 1 (2008/2009) ........................................................................................ 69 Table 30: Uptake of HPV Immunisation in Girls eligible for catch-up vaccination in Grampian (year 1) ................................................................... 69 Figure 46: Uptake of HPV Immunisation in Girls eligible for the catch-up vaccination in year 1 (2008/09) in Grampian by CHP area ............................ 70 Figure 47: Uptake of HPV Immunisation for Girls in S2 in Grampian by CHP Year 2 (2009/2010) ........................................................................................ 71 7 Foreword The Health of the Grampian Population brings together a range of information regarding the health status of the population and was produced to inform the NHS Grampian Health Plan. A life course approach has been taken in order to highlight the range of needs which require to be addressed across the population, an approach which appears particularly appropriate given the changes in the population structure which are predicted in the coming years. Whilst topics have been placed within this structure it is acknowledged that many aspects of health and disease are of importance throughout the life course, and that health and disease do not necessarily follow the traditional boundaries of young, middle and “old" age. The majority of information presented in this report is routinely available and has largely been sourced from the websites of Information Services Division (ISD), General Register Office for Scotland (GROS) and Scottish Public Health Observatory (ScotPHO). Local data that is not available from these sources has been provided by Fred Nimmo, Health Intelligence at NHS Grampian or from documents produced for NHS Grampian. 8 Childhood Children in Grampian Improving the health outcome for children and young people is a key priority for NHS Grampian and its partners. The Children’s Services (Scotland) Bill 2006; ‘Getting it right for every child’, gives clear authority and responsibility to agencies, professionals, children, families and local communities, to work together in a way that brings practicality and reality to the vision for Scotland's children. Fundamental to the transition from childhood to adulthood is good health, and NHS Grampian has made it clear that raising the health status of children and young people in Grampian is one of its main challenges. The most recent data about the population of Grampian is the mid -2008 population estimates. It is estimated that there are around 88,466 children aged between 0-14 years of age in Grampian. This accounts for around 18% of the Grampian population1. Out of which 48.7% are in Aberdeenshire, 34.9% in Aberdeen city and 16.4% in Moray (figure 1). Figure 1 below shows the percentage of children aged between 0-14 years in each of the local council area in Grampian based on the 2008 population estimates. Figure 1: percentage of children aged between 0-14 years in Grampian by local council area (based on mid 2008 population estimates) Moray, 16.4 Aberdeen city, 34.9 Aberdeenshire, 48.7 Source: GROS, 2008 It is predicted that this population would decrease from levels estimated in 2006 by approximately 12% by the year 20312. This predicted change in population would vary within Grampian. However, Aberdeenshire would see a small increase in the number of children aged 15 years and under by approximately 0.1%2. In contrast, it is projected that this population 9 would fall by about 20% and 25% respectively in Moray and Aberdeen City2 (figure 2). Figure 2: Projected percentage change in population aged 0-15 (2006 based), by Grampian Council Areas 2006-2031 Projected percentage change in population 5 0 % change -5 -10 -15 -20 -25 % Change Sco tland Grampian A berdeen City A berdeenshire M o ray -6.9 -12 -24.6 0.1 -19.9 Source: GRO 2008 Births In recent years the number of births registered in Scotland each year has been steadily increasing since 2002, with 2008 seeing the highest number of births since 19953. The number of births in Grampian follows a similar trend as can be seen in figure 3 below. In 2008, there were 6,060 live births in Grampian compared to 5,027 live births in 2002. This figure excludes deliveries at home and births at non-NHS hospitals. General fertility rates across each council area have risen in keeping with this. In 2008, Moray had a live birth rate of 63 per 1000 women aged 15-44 years compared to Aberdeenshire (61.9 per 1000) and Aberdeen City (56 per 1000). These rates are higher than the Scottish average of 57.2 per 1000 except for Aberdeen City where the rate is lower than the Scottish average4. 10 Figure 3: Number of live births per year by council area4 Source: GRO 2008 The proportion of live births to mothers of UK origin has decreased in recent years in Grampian. Births to mothers of UK origin accounted for 85% of all births in 20062008 compared with 92% of all births in 2001-2003. The proportion of births to mothers of European origin, excluding the UK and Ireland, has increased from 2% to 6% during this period, with births to mothers from all other countries increasing by about 2% to an average of 9%4. This increase in the proportion of births to mothers of non UK origin has significant implications for healthcare provision in Grampian especially in the way that a wide range of services e.g. maternity and child health services are provided. Health of newborns and young children There are a number of specific factors including lifestyle and health behaviour during pregnancy which can influence the health and wellbeing of newborns and children. Smoking in pregnancy Smoking in pregnancy is a serious health hazard for both the mother and the unborn child. The effect of smoking in pregnancy continues to affect the infant even long after birth. There is conclusive evidence that a pregnant women who smokes is more likely to have a baby with a low or very low birth weight. In Grampian the number of women who currently smoke at their first antenatal booking visit is comparable with that of other mainland boards. In 2007, 20.3% of women in Grampian were current smokers at their first antenatal booking visit compared to 24.2% in 2003. Average figures for all of Scotland during the same period were 20.8% and 25.3% respectively. 11 Figure 4: Smoking at Booking Grampian 2000-2006 Smoking at Booking 100% Percentage 80% Never % 60% Former % Not Known % 40% Current % 20% 0% 2000 2001 2002 2003 2004 2005 2006 2007 2008 r p Year end March Source: ISD 2009 In Scotland, rates of smoking in the most deprived groups are much higher despite improvements in rates across all deprivation quintiles. Similar trends are seen in Grampian and across the three local council areas. In 2007/08 only 10% of Grampian mothers in the most affluent quintile smoked during pregnancy whilst 42% of mothers in the most deprived quintile were recorded as smoking (figure 5)7 Figure 5: Trends in percentage of women during pregnancy in Figure smoking 7 Grampian 1995-2008 Trend in Percentage of Mothers Smoking During Pregnancy in Grampian (1995/2008) 60 50 % Smoking 40 30 20 10 0 1995/96 1996/97 1997/98 1998/99 1999/00 2000/01 2001/02 2002/03 2003/04 2004/05 2005/06 2006/07 2007/08 Quintile 5 49.9 51.32 51.53 48.84 49.1 53.76 50.58 56.05 54.91 49.39 53.6 41.45 42.39 Quintile 4 39.12 42.84 46.35 40.86 39.3 43.86 39.89 44.85 46.46 35.31 39.68 35.58 34.82 Quintile 3 31.1 29.32 31.46 32.51 30.26 30.17 30.3 34.78 29.8 27.05 26.18 25.18 24.5 Quintile2 20.66 20.19 19.83 19.89 18.52 20.18 18.35 19.72 21.96 19.56 18.4 17.66 16.17 Quintile 1 12.7 12.74 13.22 10.63 12.18 10.95 10.28 13.93 13.2 11.54 11.43 11.21 10.1 Year Quintile 5 Quintile 4 Quintile 3 Quintile2 Quintile 1 12 Similar trend are seen across the 3 CHPs in Grampian (figure 6). Figure 8 Figure 6: Percentage mothers smoking during by pregnancy by CHP 1995-2008 Percentage of of Mothers Smoking During Pregnancy CHP (1995/2008) 30 25 % Smoking 20 15 10 5 0 1995/96 1996/97 1997/98 1998/99 1999/00 2000/01 2001/02 2002/03 2003/04 2004/05 2005/06 2006/07 2007/08 Year Aberdeen Aberdeenshire Moray Breastfeeding19 Breast feeding has important health benefits for both mother and baby and it plays a major role in reducing health inequalities. Breastfeeding helps to protect babies against gastroenteritis, childhood asthma diabetes, obesity and ear and skin infections. In mothers breastfeeding helps to protect the mother against osteoporosis, breast and ovarian cancers. In Grampian, breast feeding rates vary widely across the 3 local authority areas. Since the introduction of the UNICEF Baby Friendly Breastfeeding Initiative the rates of breastfeeding (exclusive or combination) and exclusive breastfeeding in Grampian has been increasing. In 2007, the rate of exclusive breastfeeding in Grampian was above the HEAT target of 33.3%. However there are still some areas in Grampian where breastfeeding rates are very low. In Aberdeen City 33.7% of new mums were exclusively breastfeeding at 6 weeks; however rates were as low as 14.8% in some practices. Similarly, whilst rates of 42.9% were seen in Aberdeenshire Central, in Aberdeenshire North only 25.4% of new mums were exclusively breastfeeding. Table 1: Proportion of mothers in Grampian breastfeeding at 6 weeks 2006/2007. Exclusive breastfeeding Breastfeeding (exclusive or combination) 2007 34.6% 2006 33.6% 47.5% 47.0% Source: Grampian Breast feeding Audit, June 2009 13 Low birth weight (LBW) Low birth weight is a key child health indicator6. It is associated with infant morbidity and mortality. Babies born weighing less than 2500 grams (LBW) are more likely to die in the first year of life and have more health and educational problems at age of seven years. LBW is linked with a variety of social and environmental factors such as maternal smoking, maternal age, deprivation and drug and alcohol use. In Scotland, mothers living in a highly deprived area are twice as likely to have a LBW baby (baby weighing less than 2500 grams at birth) compared to mothers living in a less deprived areaa. As can be seen in table 2, levels of low weight live births in Grampian are comparable with Scottish figures7. In 2007, around 5.7% of singleton births in Grampian were of low birth weight7. Across the CHPs, Aberdeen City had the highest low birth weight rate. Table 2: Percentage low weight live births weight Babies in Grampian & CHPs (Singleton Births) 3 year averages 2005/06–2007/08. 2005/06 2006/07 2007/08 2008/09 Aberdeen City 7.0 6.1 6.3 6.5 Aberdeenshire 5.2 4.6 4.4 4.7 Moray 5.6 5.4 5.7 5.6 Grampian 6.2 5.4 5.5 5.7 Scotland 4.9 6.1 5.5 5.8 Source: ISD Scotland 2009 Obesity A steady increase in the body weight of high school children, as measured by BMI, has been seen over the last 12 years in Grampian in keeping with national trends. Since 2001, although there has been little change in weight in boys there has been some continued increase in weight of girls15. Figure 7: Average BMI by gender and year15 Ave rage BM I by Ge nde r 1995, 1998, 2001 and 2007 21 20.5 20 BMI 19.5 19 Males Females 18.5 18 17.5 17 16.5 1995 1998 2001 2007 Males 18.1 19.9 20.4 20.3 Females 18.2 19.9 19.9 20.6 Ye ar Source: Grampian Youth Lifestyle Survey, 2007 a ISD 2009, Births in Scottish hospitals, financial year 2007/2008 http://www.isdscotland.org/isd/6026.html 14 National data (data from 10 health boards not including Grampian) for 2007/08 demonstrate that around 20% of Primary 1 children are overweight, 7.9% obese and 3.9% severely obese20. The levels of high BMI are now similar to that of 2000/01 having decreased slightly in the last 2 years after the gradual increases seen between 2000/01 and 2005/0620. Exercise15 Exercise holds many health benefits as well as influencing levels of obesity. In the Grampian Youth Lifestyle Survey only 57% of boys and 34% of girls aged 16 years or less met the national recommendations on physical activity. Alcohol There is currently limited data available on the use of alcohol during pregnancy. Drug use Data on drug use in pregnancy is incomplete, however provisional results for 2006/07 show that of all maternities (pregnancies resulting in a live or still birth) in Grampian 3.3 per 1000 recorded drug misuse8. Rates vary significantly from year to year due to the small numbers involved8. Life expectancy at Birth Life expectancy at birth is used as the measure of the progress being made in tackling health inequalities. It is frequently misinterpreted as the number of years a child born in a particular area can, on average, expect to live. Life expectancy in a given time period is actually an estimate of the average number of years a person would survive if he or she experienced a particular area’s age-specific mortality rates for that time period throughout the rest of his or her life. The figure reflects mortality among those living in the area in each time period, rather than mortality among those born in each area. It is therefore not the number of years a person in the area could actually expect to live, as both the death rates of the area and place of residence of an individual are likely to change in the future. Over the last 20 years life expectancy at birth has been increasing for both men and women in the Scottish population generally9. Trends during the same period for Grampian population is shown in figure 8 below9. Life expectancy at birth for both male and females in Grampian has continued to increase and is significantly above the Scottish figure. 15 Figure 8: Life expectancy in Grampian compared to Scotland (1981-2007) 83 81 79 Life Years at Birth 77 75 73 71 69 67 2005-07 2004-06 2003-05 2002-04 2001-03 2000-02 1999-01 1998-00 1997-99 1996-98 1995-97 1994-96 1993-95 1992-94 1991-93 1990-92 1989-91 1988-90 1987-89 1986-88 1985-87 1984-86 1983-85 1982-84 1981-83 65 Base Year Grampian - Female Grampian - Male Scotland - Female Scotland - Male Over the same period, life expectancy across the 3 different local council areas in Grampian has also been increasing (figure 9). Figure 9: Life expectancy at birth for Aberdeen City, Aberdeenshire and Moray (1981-2007) 84 82 80 76 74 72 70 68 66 Base Year Aberdeen - Male Aberdeen - Female Shire - Male Shire - Female Moray - Male Moray - Female 16 2005-07 2004-06 2003-05 2002-04 2001-03 2000-02 1999-01 1998-00 1997-99 1996-98 1995-97 1994-96 1993-95 1992-94 1991-93 1990-92 1989-91 1988-90 1987-89 1986-88 1985-87 1984-86 1983-85 1982-84 64 1981-83 Life Years at Birth 78 In 2005-2007, the life expectancy at birth for men born in Aberdeen city (75.2), Aberdeenshire (77.5) and Moray (75.9) were significantly higher than that of the Scottish population (74.8)9. Aberdeenshire men had a significantly higher life expectancy at birth than men born in the other council areas10. Table 3: Life expectancy at birth (2005-2007)10 Scotland Aberdeen City Aberdeenshire Moray Life expectancy at birth (years) 2005-2007 Males Females 74.8 79.7 75.2 80.2 77.5 81.3 75.9 80.2 Source: GRO Scotland 2008 Life expectancy of Scottish population reaching the age of 65 has increased up to16.2 years in men and 18.8 years in women (2006-2008)10. Similar to the trends seen for life expectancy at birth, Grampian residents, and particularly Aberdeenshire residents, have a higher life expectancy at age 65 than the Scottish population generally10. Healthy life expectancy, which is an estimate of how many years a person may expect to live in good health, has increased with increasing life expectancy. However, whilst the proportion of life spent in good health does not appear to have changed this does mean that the number of years spent in poor health has increased with the populations increasing life expectancy11. In 2007 it was estimated that at birth men may expect 67.9 years and women 70.2 years of healthy life11. Although life expectancy is improving there still remains a significant difference according to level of deprivation at birth. Life expectancy at birth for those born in the 10% least deprived areas (2004-2006) in Scotland is around 13.1 years longer for men and 8.6 years longer for women than those born in the most deprived areas at this time9. Within Grampian the life expectancy at birth of those born in Aberdeen City (2003-2007) was 75 years and 80 years respectively for men and women. For the most deprived 15% of this population the life expectancy was significantly lower at 69.6 years and 75.9 years respectively10. Ill Health in Childhood Whilst the majority of children have good health there are significant numbers who have chronic health problems although of variable severity. 18% of respondents to the Grampian Youth Lifestyle Survey (2007) of secondary school children reported long term illness or disability with 10% reporting a diagnosis of asthma15. Hospital admissions Children under the age of 15 years are more likely to be admitted as an emergency than an elective admission, with children under 5 years having the highest admission rates at 128.9 per 1,000 population (Scotland)16. 17 The most common cause of elective admission in children in 2007/08 in Grampian was disorders of the digestive tract7. In Scotland this primarily included disorders of the teeth, tongue and mouth, accounting for 21.8% of elective admissions in 2007/08. These admissions were largely attributable to dental caries16. Similarly, operations on the tooth accounted for 23.4 % of all elective procedures in this age group in 2007/08 in Scotland16. This does not include tooth extraction under sedation by general dental practitioner or within the community dental services16. Other common causes of elective admission are congenital anomalies, disorders/diseases of the eye and ear, and cancers16. Figure 10: Causes of elective admissions in children in Grampian 2007/087. Source: PH intelligence NHS Grampian, 2009 Of emergency admissions to hospital in children under 15 years in Grampian both ‘respiratory disorders’ and ‘symptoms and signs without definitive diagnosis’ accounted for 26% of admissions7. ‘Unintentional injury’ accounts for 17.7% of emergency admissions7. These findings are similar to those found in the Scottish population16. 18 Figure 11: Causes of emergency admission in children in Grampian 2007/087 Source: PH intelligence NHS Grampian, 2009 In children aged 15 years and below, unintentional injuries often are the result of road traffic accidents (RTAs), poisoning, falls, burns & scalds, drowning, choking, exposure to animate/inanimate mechanical forces, assault, non RTA transport accidents, over exertion and accidental exposure to unspecified factors. The importance of reducing injuries in children is highlighted by the prominence of accidents and injuries as both a cause of death and of hospital admission in children. Table 4 shows that the crude rate of unintentional injuries in the home in children under 15 years between 2004 and 2006. The rate was significantly higher in Aberdeen City and Aberdeenshire than in Scotland16. Table 4: Rates of unintentional injuries in the home, 3 year average crude rate 2004-200617 Unintentional injuries in the home <15 years (crude rate per 100,000 population) Scotland Aberdeen City Aberdeenshire Moray Source: NHS Grampian Health Intelligence, 2009 1,123.5 1,950.0 1,346.4 1,071.1 Similar findings come from looking at single year figures for the year ending 31 March 2008. Emergency admissions as a result of an unintentional injury in Grampian accounted for 13% of such admissions in Scotland. The higher than expected results for Grampian were most prominent within the younger age groups7 During the same period, the standardised discharge ratio also showed that Grampian as a whole and Aberdeen City CHP had significantly more emergency admissions in children under 15 years compared to Scotland17. The increased rates in Grampian could be due to admission practices at local hospitals, small numbers as well as an absolute level of injuries. Thus caution should be applied when interpreting the data. 19 Table 5: Emergency hospital admissions as a result of an unintentional injury in Children aged under 15 in Grampian, Community Health Partnerships, and Scotland year ending 31 March 2009 Standardised Discharge Rate SDR Scotland Grampian Aberdeen City Community Health Partnership Aberdeenshire Community Health Partnership Moray Community Health & Social Care Partnership 100.0 123.1 Confidence intervals Lower Upper 100.0 100.0 115.8 130.4 157.3 143.4 171.2 108.4 98.6 118.3 92.8 77.1 108.5 Trend data from the information service division ISD, Scotland shows that on the overall the incidence of unintentional injury discharges from hospital per 100,000 population in Grampian is falling. In 2008/09 the rate per 100,000 population in Grampian was 1,346 compared to 1709 per 100,000 population in 2004/05. Table 6: Unintentional injury in children, 2007/087 Number of children (Grampian) % of Scottish population in age group Admissions for unintentional injury (Grampian) % of Scottish emergency admission for unintentional injury Age <1 year 6,269 10.5% 84 Age 1-4 23,143 10.4% 247 21% 14% Source: NHS Grampian Health Intelligence, 2009 Death due to unintentional injury in children under 15 years is a very rare event. In the 5 year period between 2004 and 2008, there were a total of 117 deaths in children less than 15 years due to unintentional injury, 15 of these where in Grampian. During this period the Standardised Mortality Ratio (SMR) showed that death from unintentional injury in Grampian children was 24.3% (SMR 124.3 CI 61.4 -187.2) higher than the Scottish rate. This was however not statistically significant. SMRs reported across the Scottish health boards ranged from 154.2 in Western Isles to 62.9 in Orkney 192 in Fife to 71.9 in Ayrshire and Arran. It is important to point out that these are based on very small numbers and the ratios will fluctuate markedly from year to year 20 Preventing illness in childhood Immunisation Many infectious diseases which can cause morbidity in childhood are included within the childhood vaccination schedule. This has resulted in continued low levels of these infectious diseases. The World Health Organisation (WHO) recommends that at least 95% of children should receive three primary doses of diphtheria, tetanus, polio and pertussis in the first year of life; and at least 95% should receive a first dose of a measles, mumps and rubella (MMR) containing vaccine by 2 years of age. In addition, at least 90% should receive a booster dose of tetanus, diphtheria and polio between 13 to 18 years of age. Vaccination uptake rates in Grampian remain satisfactory and in line with rates seen in Scotland. In Grampian, between 1st April and June 2009, 95.2% and 92.3% of eligible 2 year olds and 5 year olds had received their MMR1 and MMR2 vaccines respectively (table 7 & 8)21. Table 7: Uptake rates-Percentage completing primary course by 24 months of age (1 April to 30 June 2009) in Grampian, Grampian CHP areas and Scotland Percentage completing primary course by 24 months of age Diphtheria Tetanus Pertussis Polio Hib MenC PCV MMR1 Aberdeen City CHP 98.6 98.6 98.6 98.6 98.2 94.8 95.7 95.8 Aberdeenshire CHP 98.1 98.1 98.1 98.1 97.8 96.7 97.2 94.8 Moray CH&SCP 99.2 99.2 99.2 99.2 99.2 98.5 98.5 94.6 Grampian 98.4 98.4 98.4 98.4 98.1 96.1 96.7 95.2 Scotland 98.4 98.4 98.3 98.3 98.1 96.3 96.4 93.3 Source ISD 2009 Similar trend are seen across the CHPs (table 6 and 7). However, there is increasing concerns across the UK and Scotland with increasing number of measles cases. Since the start of 2009, there have been 96 notifications of measles in Scotland with 16 of these cases laboratory-confirmed21. These figures include two children under 13 months old and none of the children had received MMR vaccination. Children less than 13 months of age are normally too young for MMR vaccination and generally rely on high levels of vaccination in the community (Herd immunity) to prevent circulation of the infection21. This highlights the need to maintain and improve current levels of vaccination uptake. 21 Table 8: Percentage completing primary course by 5 years of age (1 April to 30 June 2009) in Grampian, Grampian CHP areas and Scotland Percentage completed primary course by 5 years D T P Pol Hib MenC MMR1 Percentage completed booster course by 5 years D T P Pol MMR2 97.7 97.7 97.7 97.7 96.3 94.2 96.3 94.0 94.0 94.0 94.0 92.2 97.0 97.0 97.0 97.0 96.5 95.9 95.6 92.9 92.9 92.9 92.9 91.0 99.1 99.1 99.1 99.1 99.1 99.1 97.4 97.0 97.0 97.0 97.0 96.1 97.6 97.6 97.6 97.6 96.9 95.8 96.2 94.0 94.0 94.0 94.0 92.3 Scotland 98.3 Source: ISD 2009 98.3 98.3 98.2 97.3 97.6 96.2 89.6 89.6 89.5 89.5 87.5 Aberdeen City CHP Aberdeenshire CHP Moray CH&SCP Grampian Screening The aim of population screening programmes is to identify those who are at increased risk of having or developing a particular disease so that early diagnosis, prevention and treatment may be provided. This should then reduce the burden of deaths and ill health as a result of the disease. Screening in pregnancy Women are screened during pregnancy for the following infectious diseases: hepatitis B; rubella; syphilis; and HIV; All of these diseases can have significant implications for the child, for future pregnancies, as well as for the mother. In Grampian, the number of women engaging with these services is good with an uptake of over 95% in recent years22. Screening for Down’s syndrome and Neural Tube Defects, as well as Sickle Cell Disease and other foetal anomalies, is also offered during pregnancy. Work is underway in Grampian to implement the changes to the national screening programme for these conditions. Recent surveys indicate that more and more Grampian women are accepting to be screened. This increase in screening request and new developments in the screening programme means that more resources are required to maintain the current service workload. Screening in children Screening in the first days of life involves a physical examination and bloodspot testing. The bloodspot currently tests for three metabolic disorders including Cystic Fibrosis, Congenital Hypothyroidism and Phenylketonuria. This is currently being extended to detect Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) and Sickle Cell Disease, disorders in which an early diagnosis can offer considerable health advantages. Laboratory testing of bloodspots is undertaken at the Scottish Newborn Screening Laboratory in Glasgow, but investment is required within Grampian in order to ensure that staff and pregnant women understand the implications of changes to this screening test and can make informed choices. In addition, the follow-up of any abnormalities detected will impact on local resources. 22 Children in NHS Grampian are also invited for screening through the Universal Newborn Hearing Screening Programme and the Pre-school Orthoptic Vision Screening Programme. Dental health23 Dental health in Grampian has fluctuated over the years however the 2007/2008 survey of oral health in Primary 1 children showed the best results to date with 58.6% of children showing no signs of dental decay. This was close to the target of 60% to be achieved by 2010 and just above the Scottish level of 57.7%. Despite the improvements over 500 children started school with dental abscesses and/or gross disease in Grampian, many requiring urgent care. Significant discrepancies are seen between the community health partnerships, with Aberdeen City continuing to be well below the national target. 13.7% of children starting school in Aberdeen City in 2007/08 had gross disease. Figure 12: Percentage of Primary 1 children with no decay. Source: NHSGrampian National Inspection Programme, 2007/2008 Results vary significantly even within council areas. The largest variations are seen within Aberdeen City. In some schools over 90% of primary 1 children had no decay whilst in others less than 20% had no decay. Nationally there is a clear correlation between tooth decay and deprivation with the most deprived groups some way from reaching the target of 60%. 23 Lifestyle Issues in later childhood There are a number of behaviours influencing health that may be explored in later childhood including alcohol, smoking, drug use and sexual behaviour. Alcohol There was a significant decrease in the proportion of 13 and 15 year olds in Grampian who had ever had an alcoholic drink from 91% of 15 year olds and 71% of 13 year olds in 2002 to 87% and 60% in 2006 respectively. Similar declining trends in drinking prevalence of 15 and 13 year old school children although to a lesser degree were noticed across the three Grampian Local Authority Areas during the same period (figure 13).24 15 year olds Moray Aberdeenshire Aberdeen city Grampian Moray Aberdeenshire Aberdeen city 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Grampian Percentage Figure 13: Percentage of school-aged children who have ever had a proper alcoholic drink in Grampian 2006 compared with 2002 13 year olds 2002 2006 Source: Scottish Schools Adolescent Lifestyle and Substance Use Survey (SALSUS), 2008 In 2006, boys in Aberdeen city were significantly more likely to have an alcohol drink in the last week prior to the survey compared to girls. There was no significant difference in the proportion of boys and girls in Aberdeenshire and Moray who had had an alcoholic drink in the last week prior to the survey. The Grampian Youth Lifestyle Survey 2007 of secondary school pupils found that 45% of pupils reported consuming alcohol in the seven days prior to the survey, ranging from 28% of 1st year students to 94% of 6th year students15. Whilst there was a decrease in the number of young people drinking alcohol in comparison with 200115 consistent with the SALSUS 2008 survey24, the average number of units consumed by young people who did drink had increased15. Numbers of young people recorded to be drinking on 3 or more days per week has remained static since 199515. 24 Smoking The numbers of young school-aged children in Grampian reporting that they smoke regularly is decreasing. The 2006 Scottish Schools Adolescent Lifestyle and Substance Use Survey SALSUS showed similar decreasing trends across the 3 local council areas (Figure 14). There is no significant difference in the proportion of boys and girls who smoke regularly24. The same survey found that smoking in secondary school pupils had decreased overall to 12%15. Figure 14: Percentage of school-aged children who are regular smokers in Grampian 2006 compared with 2002 30% Percentage 25% 20% 15% 10% 5% 15 year olds Moray Aberdeenshire Aberdeen city Grampian Moray Aberdeenshire Aberdeen city Grampian 0% 13 year olds 2006 2002 Source: Scottish Schools Adolescent Lifestyle and Substance Use Survey (SALSUS), 2008 Drugs Both the Grampian Youth Lifestyle Survey 2007 and the SALSUS surveys have shown a decrease in the number of Grampian children (13 and 15 year olds) being offered drugs15,24. There has also been a decrease in the number of Grampian children reporting that they have ever used or taken drugs in 2006 compared with 2002. Similarly the was a decrease in the number of children in both age groups who reported that that they had used drugs in the month prior to the 2006 survey. However, across the three CHPS, there was a significant decrease in the proportion of 15 year olds and 13 years olds in Aberdeenshire who had ever used drugs in 2006 compared to 2002, whereas in Aberdeen city, this decrease was only seen in 15 year olds. In Moray there was no significant change in the proportion of children of both age groups who had ever used a drug in 2006 compared to 2002. In the one month prior to the 2006 survey compared to the 2002 survey, the was a significant decrease in the proportion of 13 and 15 year olds who reported that they had used drugs in Aberdeen City and Aberdeenshire. In Moray, the decrease was only seen in 15 year olds. In those who reported that they had used drugs, the average age when a pupil tried drugs was 12 years in Aberdeen City compared to 13 years in Aberdeenshire and Moray24. The Grampian Youth Lifestyle survey has also shown a decreasing trend in the use of drugs. The survey showed that 14% of pupils reporting trying drugs in the 2007 survey compared with 21% in 2001 and 30% in 199815. Cannabis 25 remains the most widely used drug. Of concern 14% of children who had tried drugs reported using cocaine and 19% had used gas/glue and other solvents15. Figure 15: Percentage of school-aged children who have used drugs in the month prior to the survey 45% 40% Percentage 35% 30% 25% 20% 15% 10% 5% 15 year olds Moray Aberdeenshire Aberdeen city Grampian Moray Aberdeenshire Aberdeen city Grampian 0% 13 year olds 2006 2002 Source: Scottish Schools Adolescent Lifestyle and Substance Use Survey (SALSUS), 2008 Sexual health25 Reducing unintended teenage pregnancy is a national target for the Scottish Government. Whilst for some young women this will be a positive life decision, in many cases the pregnancy will be unplanned, unwanted and an indication of unsafe sexual behaviours. Teenage pregnancy rates have been fairly steady across Grampian over the last 14 years (figure 16). From 2001 onwards, Grampian rates (all age groups) have been consistently lower than the Scottish average. Over the period 2005-2007 just over half of teenage pregnancies in those less than 18 years in Grampian resulted in abortions. 26 Figure 16: Teenage Pregnancy rates per 1000 women in Grampian and Scotland 1994-2007 70.0 Rates per 1,000 women 60.0 50.0 Scotland > 20 Grampian >20 40.0 Scotland >18 Grampian >18 30.0 Scotland >16 Grampian >16 20.0 10.0 19 94 19 95 19 96 19 97 19 98 19 99 20 00 20 01 20 02 20 03 20 04 20 05 20 06 20 07 - Year Source: ISD 2009, Teenage pregnancy data Teenage pregnancy is associated with deprivation and rates of teenage pregnancy in deprived areas are more than three times those of the least deprived areas (Figure 17). Figure 17: Teenage pregnancy in Grampian by age group and deprivation quintile, 2007 Source: ISD 2009, teenage pregnancy data However, within Grampian, Aberdeen City has rates above the national average whilst rates in Aberdeenshire and Moray are significantly lower. Rates of teenage pregnancy in the two most deprived quintiles were higher than equivalent communities in Scotland each year between 2003-2006, in 2007 this was only seen in SIMD 4. 27 Sexually transmitted infections (STIs) affect all age groups. Of concern are the increasing levels of these infections particularly among young people. Almost a quarter of all acute STI diagnoses, in GUM clinics in 2008, were in those aged less than 20 years26. The Grampian Youth Lifestyle Survey 2007 highlighted concern over knowledge of sexually transmitted infection amongst secondary school pupils. Knowledge of HIV amongst young people was found to have fallen since 200115. However, 74% of pupils reported never to have had sexual intercourse and of those who were sexually active an increased number reported using condoms (90%)15. Chlamydia27 There has been a 26% increase in Chlamydia between 2003 and 2007. Over 70% of diagnoses are in those less than 25 years, the majority aged 20-24. Rates of diagnoses in Grampian in 2007 were just below those of Scotland. Genital herpes27 Diagnoses have been increasing in Scotland. More than half are in women and most diagnoses were made in women aged 20-24 and men aged 25-34. Rates in women in Grampian are among the lowest at around 30 per 100,000, however rates in men are the second highest in Scotland at around 45 per 100,000. Syphilis27 Diagnoses have increased since the reemergence in 2000/2001. Between 2003 and 2007 there has been a three-fold increase in diagnoses. Increases have been primarily in men who have sex with men (MSM), however, between 2006 and 2007 the number of cases of heterosexually acquired syphilis increased by 28%, with the largest increases in those aged 20-24 and aged 35-44. Rates of diagnoses of syphilis in men in Grampian are below those for Scotland. Genital warts27 The annual number of new diagnoses in both men and women has increased by 35% over the past 10 years. In 2007 more than two thirds of new diagnoses in men were aged 20-34, with two thirds of female cases in those aged 15-24. The greatest increases in 2007 were among men aged 25-34 and in women aged 1519. Rates in Grampian are around the lowest in Scotland in 2007. 28 Mortality in infants and childhood Infant mortality (death rates in infants) is a useful indicator of the health of the overall population and the quality of health services. It is strongly associated with deprivation. Grampian stillbirth, perinatal, neonatal and infant death rates compare favourably with the Scottish rate5. Table 9: Stillbirth and infant mortality rates per 1000 live births 3 year averages 2006-20085 Scotland Aberdeen City Aberdeenshire Moray Stillbirths Infant deaths 5.4 6.0 4.3 5.5 4.5 4.6 3.1 3.5 . However, within the three local council areas in Grampian, variations in these rates can be seen5. Infant mortality rate (2006-2008) in Aberdeen city was 4.6 per 1000 live births compared to 3.1 and 3.5 per 1000 live births in Aberdeenshire and Moray respectively. The rate in Aberdeen City was higher than the corresponding figure for Grampian and the Scottish. Caution must however be exercised when interpreting these figures as death in infancy is a rare event and even one additional death, or life saved can make a large difference to the rates calculated as they are based on small numbers of deaths. Childhood mortality: The number of deaths that occur in childhood in Scotland is small in keeping with most developed countries. In Grampian there were only 26 deaths in children under the age of 15 years in 20087. Of those deaths that do occur, many are related to genetic diseases which cause death in early childhood. The small numbers of deaths involved make it appropriate to analyse trends at a Scottish level rather than within Grampian. Preliminary 2008 figures show that more than two thirds of the 356 deaths in childhood in Scotland occurred in children under the age of one with almost 50% occurring before the age of 4 weeks12. The major causes of death in children are perinatal conditions, such as disorders relating to prematurity and respiratory and cardiovascular disorders. Congenital anomalies are the second most common cause of death13. The main causes of death in childhood in Scotland between the age one and fourteen are external causes of death (29%) which include accidents, self harm or assault, or cancer (18%)12. 29 Figure 18: Deaths in children under 15 years of age by SIMD14 There is a clear association between rates of death in children and the environment into which they are born in terms of the levels of deprivation of their parents14. 30 Working age population The working age population accounts for 68% of the male population and 59% of the female population of Grampian1. Within Grampian, corresponding figures for working age group are for Aberdeen City (71% of male population and 62% of female population), Aberdeenshire (66% male and 58% female) and Moray (66% male and 55% female) Based on the 2006 mid year population estimates, it is projected that the population aged 15-64 years will decrease by 5 % in Grampian by 2031. Between 2011 and 2031, Aberdeen City and Moray will seen a year on year decrease in the population of those aged 15- 64 years, whereas, Aberdeenshire will see a slight increase in the working age during the same period (table 10). Table 10: Projected percentage changes in population (2006-based), by council areas and Grampian selected years 2011 Aberdeen City Aberdeenshire Moray Grampian 2016 0 4 1 2 2021 -3 7 1 2 2026 -7 8 -2 1 2031 -10 10 -4 0 -16 8 -10 -5 Source GRO, 2009 Mortality All ages The main causes of death in the Scottish population are ischaemic heart disease and malignancy and this is mirrored in the Grampian population. In 2008, there were 5322 deaths (all age groups) in Grampian compared to 5317 in 2007. Of the 5322 deaths in Grampian in 20087; 1479 deaths (28%) were due to cancer with 6% of all deaths due to cancer of the bronchus and lung and 2% due to cancer of the breast, 824 deaths (16%) were due to coronary heart disease, 675 deaths (13%) were due to diseases of the respiratory system, 505 deaths (10%) were due to cerebrovascular disease, 286 deaths (5%) were due to mental and behavioural disorders, 253 deaths (5%) were due to diseases of the digestive system, with 1% of all deaths due to chronic liver disease, 217 deaths (4%) were due to external causes including accidents (2% of all deaths), falls, poisoning, intentional self harm and assault. 31 Figure 19: Main causes of death in all age groups in Grampian, 2008. Others 26% Cancer 28% Injury etc 4% Digestive 5% Respiratory 13% CHD 15% Stroke 9% Source: NHS Grampian Public Health Intelligence 2009 Working age group Mortality in the working age population under 65 years of age is described as premature mortality. The main causes of death in all age groups in Scotland are somewhat similar to the most frequent causes of death in those aged 65 years and below except that in those aged 65 years and below, lifestyle risk factors such as alcohol and drug misuse contribute significantly to the main causes of death in this age group28. This difference can be seen in table 11 below. 32 Table 11: Most frequent causes of death in Scotland by age group Most frequent causes of death in Scotland, 2005-2007 All ages 1. Acute myocardial infarction 2. Cancer of the bronchus and lung 3. Chronic ischaemic heart disease 4. COPD 5. Pneumonia 6. Stroke 7. Dementia 8. Sequelae of cerebrovascular disease 9. Breast cancer 10. Alcoholic liver disease Those aged 65 years and below 1. Cancer of the bronchus and lung 2. Acute myocardial infarction 3. Chronic ischaemic heart disease 4. Alcoholic liver disease 5. Breast cancer 6. COPD 7. Intentional self-harm 8. Mental and behavioural disorders due to alcohol use 9. Mental and behavioural disorders due to opioid use 10. Oesophageal cancer Source Scottish Public Health Observatory, 2009 In Grampian in 2008 there were 1023 premature deaths7. Of these deaths (figure 20); 362 deaths (35%) were due to cancer, 140 deaths (14%) were due to external causes, 131 deaths (13%) were due to coronary heart disease, 79 deaths (8%) were due to diseases of the digestive system, 44 deaths (4%) were due to diseases of the respiratory system, 29 deaths (3%) were due to cerebrovascular disease. Figure 20: Main causes of premature death in Grampian, 2008. Others 23% Cancer 35% Injury 14% Digestive 8% Respiratory 4% CHD 13% Stroke 3% Source: NHS Grampian Public Health Intelligence 2009 33 Morbidity Long-term conditions contribute significantly to both mortality and morbidity within the population. Although long-term conditions can affect any age group, they are more common in the elderly population. The prevalence of long-term conditions is increasing because of the increasingly elderly population and medical advances that has allowed people to live longer with these conditions. These long-term conditions have significant impact on the individual patient, and their family and place an increasing strain on health services due to the need for ongoing medical care. In the 2001 census, around 20% of adults in Scotland reported having a limiting long-term illness17. Rates in each council area in Grampian were significantly below the Scottish rate17. Table 12: Percentage of population reporting limiting long-term illness, 2001 census17 Adults reporting limiting long term illness 17.5% 15.3% 16.7% 20.3% Aberdeen city Aberdeenshire Moray Scotland Source: Scottish Public Health Observatory, 2009 The prevalence of chronic, long-term conditions is associated with social deprivation. Whilst just over 10% of the least deprived population reported limiting long term illness over 20% of the most deprived population reported these problems17. Neuropsychiatric conditions, disorders of vision, hearing loss and alcohol use disorders are dominant as nonfatal but disabling conditions. It is estimated that neuropsychiatric disorders, including depression, alcohol use disorders, dementia and drug use disorders, cause around one third of the ‘years of life disabled’ in high income countries such as the UK. Other leading causes of disability are osteoarthritis, chronic obstructive pulmonary disease, diabetes mellitus and asthma29. Table 13: Incidence rates of long term condition discharges from hospital per 100,000 Population, Grampian and Scotland 2008/2009 Scotland Grampian Aberdeen City Aberdeenshi re Moray Diabete s Mellitus 42 33 Hypertensi ve Diseases 19 10 Angina Pectori s 109 62 Acute Myocardi al Infarction 151 155 Other Ischaemi c Heart Disease 137 167 Heart Failur e 92 79 COP D 126 95 Asthm a 71 55 33 8 64 168 160 63 104 67 28 51 14 6 49 96 140 172 160 213 86 104 78 127 47 51 Source ISD 2009 34 Hospital admissions30 The most common diagnoses resulting in hospital admission in the Grampian population in 2007/08 were diseases of the digestive system, followed by diseases of the circulatory system and neoplasm’s (table 14). Admissions due to ‘injury, poisoning and certain other consequences of external causes’ and diseases of the respiratory system also resulted in significant numbers of hospital admissions. Table 14: Incidences rates of main diagnosis discharges from hospital per 100,000 population by Financial Year in Grampian (all ages) Rates per 100,000 Population by Financial Year Diagnosis Description 2004/05 2005/06 2006/07 2007/08 2008/09 Certain infectious and parasitic diseases Neoplasms Diseases of the nervous system Diseases of the eye and adnexa Diseases of the circulatory system Diseases of the respiratory system Diseases of the digestive system Diseases of the skin and subcutaneous tissue Diseases of the musculoskeletal system and connective tissue Diseases of the genitourinary system Injury, poisoning and certain other consequences of external causes Source ISD 2009 235 793 228 786 225 768 239 772 249 844 261 264 250 233 244 169 189 222 223 300 1,277 1,242 1,293 1,250 1,267 913 950 1,012 1,032 1,029 1,909 1,955 1,960 2,115 2,341 277 275 282 275 285 846 997 1,013 999 1,084 903 910 918 905 1,017 1,508 1,502 1,453 1,494 1,477 GP consultations31 The table below demonstrates that for the selected clinical conditions which are part of the Quality and Outcome Framework, prevalence in Grampian is comparable to prevalence in the Scottish population. A number of these conditions will be examined in more detail later in the report. 35 Table 15: QOF prevalence data per 100 registered patients31 QOF prevalence data for Scotland and Grampian for 2007/08 Grampian Scotland Hypertension 12.09 12.88 Obesity 8.63 7.34 Depression 5.27 6.95 Asthma 5.60 5.51 Coronary Heart Disease 4.04 4.48 Hypothyroidism 3.98 3.25 Diabetes 3.49 3.70 Chronic Kidney Disease 3.27 2.71 Stroke and TIA 1.75 2.00 COPD 1.36 1.87 QOF prevalence data for Scotland and Grampian for 2007/08 (cont.) Grampian Scotland Cancer 0.92 1.09 Heart failure 0.81 0.86 Mental health 0.72 0.79 Epilepsy 0.66 0.70 Dementia 0.61 0.57 LVD 0.51 0.61 Learning disabilities 0.46 0.43 Behavioural risk factors Many of the conditions resulting in significant mortality and morbidity in the population are potentially preventable, particularly as a cause of premature mortality. On a global scale it is estimated that at least 80% of premature deaths from cardiovascular disease and strokes could be prevented through a healthy diet, regular physical activity and avoiding the use of tobacco32. Smoking In 2004 an estimated 24% of all deaths in Scotland, or 13,473 deaths, were attributed to smoking33. This figure does not include those who may have died due to passive smoking. Findings are similar in both men and women although there are signs that smoking attributable deaths in men are falling whilst little change has been seen in women33. In Grampian 21% of all deaths, or 5,418 deaths, between 2000-2004 were estimated to be attributable to smoking33. The proportion of individuals smoking generally decreases with age34. Although traditionally smoking rates were significantly higher amongst men there is now little difference between the sexes in the levels of smoking34. Higher proportions of individuals from the most deprived areas are smokers. The 2007 Scottish Household Survey shows that 42% of individuals in the 15% most deprived communities smoke in comparison to 23% in the rest of the population34. 36 Figure 21: Percentage of population smoking by SIMD quintile, Scotland 200734. The estimated percentage of smokers in the adult population by age and sex in 2003/04 is shown in the table below. Rates of smoking at this time were highest in Aberdeen City (26.5%) and lowest in Aberdeenshire (22.8%)30. Both the QOF prevalence figures31 and new survey results from the Scottish Health Survey 200734 suggest around 21% of the population are smokers. This would represent an improvement in levels of smoking in Grampian. Table 16: Estimated percentage of smokers in the adult population by age and sex, 2003/0433 Males Females All 16-24 28.2 29.6 28.9 25-34 31.6 27.6 29.6 35-44 26.9 25.1 26.0 45-54 26.1 25.5 25.8 55-64 22.8 22.7 22.8 65-74 16.5 17.3 16.9 75+ 9.9 10.4 10.2 16+ 25.2 23.5 24.4 Alcohol Alcohol intake in excess of recommended limits and binge drinking which, is defined as drinking over double the daily recommended limit both have health consequences. These consequences may be long term health problems or acute illness; and very often there are also associated significant social consequences. 1 in 20 deaths in Scotland are estimated to be attributable to alcohol whilst 1 in 20 of all patient discharges is related to alcohol35. In Grampian there were 97 deaths on average per year between 2005 and 200735. Deaths attributable to alcohol are proportionately higher in younger age groups and in men. One in four deaths in men aged 35-44 years old in Scotland in 2003 were attributable to alcohol consumption35. Whilst it is well recognised that diseases such as alcoholic liver disease are wholly attributable to alcohol therefore potentially avoidable, there are many illnesses not routinely recognised by the public to be related to alcohol use. For example approximately 20% of breast cancer mortality and morbidity in Scotland is estimated to be due to alcohol consumption35. It is estimated that around 22% of the adult population drink alcohol at hazardous or harmful levels with little variation in these figures seen across Scotland36. Around 5% 37 of the adult population is thought to have alcohol dependence36. Some estimates of the levels of harmful alcohol use in the population are shown in figure 22 below36. Figure 22: Estimated levels of harmful drinking in the adult Scottish population by type of harmful drinking36. There is little variation in the proportion drinking above recommended limits by age until age 65-74 when consumption starts to reduce36. However, the proportion of each age group consuming more than twice the recommended limits in the week preceding the survey decreases with age36. There is a mixed picture in regard to drinking patterns according to level of deprivation. Average consumption on the heaviest drinking day increases with increasing deprivation in men however there is little difference between women in the SIMD quintiles36. In contrast men and women in the most affluent quintile are more likely to exceed weekly limits36. Obesity Overweight and obesity are most commonly assessed using the body mass index (BMI) which is calculated according to weight and height. Obesity is defined as a BMI greater than 30 kg/m2 which is a level at which the risk of developing many diseases increases. There is limited data available on the prevalence of obesity in the population. Quality and Outcome Framework data estimates a prevalence of obesity in the Grampian population of 8.63 per 100 population31 but is likely to significantly underestimate the extent of the problem. Estimates from the 2003 Scottish Health Survey suggest that around 24.2% of the Scottish population are obese37. By both these measures, levels of overweight and obesity are similar in the Grampian population and in the Scottish population31,37. The mean BMI in men in Scotland is estimated as 27.0 kg/m2 and in women 27.2 kg/m2 37. The number of individuals who are overweight or obese tends to increase with age until age 74 before declining37. There is an association between obesity and increasing deprivation however the picture is mixed in regard to overweight. Men in the highest income households are more likely to be overweight whilst the women in these household are least likely to be overweight37. Exercise The recommended levels of physical activity for health are: Adults: 30 minutes of moderate intensity activity on 5 or more days per week Children: 60 minutes of moderate intensity activity on 5 or more days per week National survey data indicates that 44% of adult men and 33% of adult women meet the minimum recommended activity levels for health. Local data shows that only 57% 38 of boys and 34% of girls (aged 12-16 years) and 38% of male and 24% of females (aged 18-25 years) achieve the physical activity recommendations38. Figure 23: Percentage of selected Grampian population groups taking the recommended level of physical activity per week. Percentage (%) Percentage of population taking recommended levels of exercise per week 90 80 70 60 50 40 30 20 10 0 Target Male Female All Adults Young People (aged 18-25) Youths (aged 1216) Screening in adults A number of screening programmes are offered to the adult population with new programmes recently offered or likely in coming years. Screening for breast cancer is offered to all women aged 50 to 70 years of age. In contrast to screening for cervical cancer the uptake of breast cancer screening has remained consistently above the target of over 80% of eligible women attending for screening34. In Grampian the uptake of breast screening has risen to 83.1% of eligible women for the 3 year period 2005/06 – 2007/0839. This compares to a Scottish average of 76.2% and is one of the highest rates amongst the Scottish health boards39. Screening for cervical cancer is the longest running population screening programme. Through the detection of premalignant conditions, cervical screening has the ability to prevent the occurrence of cancer as well as detecting malignancy at an earlier stage. In recent years a consistent decline has been seen nationally in the uptake of cervical screening, especially in younger age groups, with uptake falling to 69.7% in Scotland in 2007/0840. A rise in uptake of 4% was seen in 2008/09 thought to be attributable to the publicity around the death of Jade Goody from cervical cancer and the HPV vaccination campaign40. Whilst this is promising uptake remains significantly below levels seen 1995 to 200540. Bowel cancer is the third most common cancer in the UK and the second leading cause of cancer death41. The screening programme aims to identify cancers at an early stage but also prevent some cancers by removing polyps before they develop any malignant changes. The programme is being rolled out across Scotland between 2007 and 2009 and involves men and women aged 50-74 years being screened every two years. Grampian was a pilot area for the programme and therefore among the first of the health boards to provide this service. Uptake in Grampian between June 2007 and May 2009 was 60.5%, above the target of 60% and the national figure of 56.8%41. Uptake in Grampian, as in Scotland, is lower amongst men (56.5%) than women (64.4%)41. More cancers were detected in men than in women41. Uptake is lower in deprived areas with an uptake of 64.8% in the 39 most affluent areas in Grampian compared with an uptake of only 42.2% in the most deprived areas41. The Diabetic Retinopathy Screening Programme in Grampian (2000) for ages 12 and over continues to experience a high volume of referrals for screening. This reflects the substantial and ongoing increase in the number of people in Grampian being diagnosed with diabetes22. Over the 5 years since the establishment of the service until 2006 the number of people diagnosed with diabetes in Grampian almost doubled22. Information from the 2005 Scottish Diabetes Survey suggested that 77.9% of people registered as having diabetes mellitus in Grampian had a record of having retinal screening within the previous 15 months. These rates were higher than the Scottish average of 67.7%22. Screening for Abdominal Aortic Aneurysm is also likely to be introduced in coming years for men over 65 years. The prevalence of this condition is high (5% in men aged 60-69) and increases with age22. It may remain asymptomatic for years however aneurysms over a certain size carry a high risk of rupture22. Mortality after rupture is high – approximately 80% in those who reach hospital and 50% in those undergoing emergency surgery22. Introduction of this new screening programme nationally will require investment in resources within Grampian and produce significantly increased activity within radiology and vascular surgical departments both during the screening process and in treating those identified. 40 Infectious diseases In developed countries infectious diseases no longer account for the majority of illness and death. However, there are a number of infectious diseases which are of concern currently. Hepatitis C42 Hepatitis C was first identified in 1989 and is a slowly progressive disease of the liver. It can lead to liver failure and/or liver cancer, however it is potentially treatable. In many cases it will cause no symptoms leaving infected individuals unaware that they may have the disease whilst complications are developing. There are estimates that around 1% of Scotland’s population has been infected with the great majority aged less than 50 years. As at 31 March 2009, approximately one in 240 of Scotland’s population had been diagnosed hepatitis C antibody-positive. Around 11% of those identified in Scotland are resident in Grampian. Since 1990, a total of 2928 cases of hepatitis C antibody positive cases have been diagnosed in Grampian. Figure 24 gives a break down of the number of cases of hepatitis C antibody positivity per year. It is estimated that the number of undiagnosed hepatitis C antibody-positive cases in Scotland still exceeds the number of diagnosed cases. Figure 24: Persons in Grampian reported to be hepatitis C antibody positive 1999 to 31 March 200943 350 300 Numbers 250 200 150 100 50 0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 290 259 245 204 198 167 Year 177 187 148 184 58 Source: HPS weekly surveillance report, July 2009 HIV27 New diagnoses of HIV have increased in recent years in Scotland and in Grampian. This may be in part attributable to the increasing trend to offer and recommend an HIV test to all genitourinary medicine clinic attendees suspected of having a sexually transmitted infection. Since 2000 more new HIV infections have been diagnosed in heterosexual individuals than in men who have sex with men (MSM). Around 76% of non-intravenous drug using heterosexual cases probably acquired their infection abroad, predominantly in African countries. 41 Figure 25: HIV incidence rate by year, Grampian and Scotland44 Source: Health Protection Unit NHS Grampian There has been a downward trend in AIDS diagnoses and AIDS related deaths since the introduction of effective therapies in 1996 – around three-fold and twelve-fold decreases respectively. In 2007, 2668 HIV-infected persons were receiving HIV specialist care in Scotland, 203 in Grampian. 42 Elderly population The population of people aged 65 years and over in Grampian has been increasing steadily over the last 40 years. The greatest rise has been in the over 85 year age group (figure 26). The 2008 mid-year population estimate shows that there are currently about 86,398 individuals aged 65 years and over in Grampian. This accounts for about 16% of the population of Grampian. Overall, this increase in the elderly population is significantly more in female (24%) than in the male (14%) population1. Figure 26: Elderly population of the North east hospital region (1959-2008) 20000 18000 16000 14000 Population 12000 10000 8000 6000 4000 2000 Year Males 75-84 Females 75-84 Males 85+ Females 85+ Source: GROS, 2009 Based on 2006 population estimate, it is projected that the population of those aged 65 years and over in Grampian will increase by 51% by 2031 making up 28% of the total Grampian population2. Within Grampian, the projected population of those of pensionable age by 2031 will be greatest in Aberdeenshire (75.9%) compared to Aberdeen City (27.5 %) and Moray (38.8%)2. 43 2007 2005 2003 2001 1999 1997 1995 1993 1991 1989 1987 1985 1983 1981 1979 1977 1975 1973 1971 1969 1967 1965 1963 1961 1959 0 Table 17: Projected population aged 65 and over (persons) 2006-2031 in thousands Age Group Aberdeen city Aberdeenshire 2006 2011 2016 2021 2026 2031 65-74 16.9 16.8 19.9 22.3 23.3 24.5 75+ 15.3 16.5 17.6 18.9 22.6 25.5 65-74 20.0 23.7 30.0 33.8 35.2 37.9 75+ 16.5 19.2 22.8 28.1 35.9 42.3 65-74 8.5 9.2 10.6 11.3 11.4 12.4 6.8 7.8 8.9 10.4 12.4 13.8 Moray 75+ Source: GROS, 2009 In those aged 75 year and over, the projected increase in the population in Grampian is 27.6% (49,304) by 20162. By 2031 the estimated increase in this section of the population Figure 27) is around 111% on 2006 values2. This projected increase is above the national projections of an 81% increase2. The projected increase in the Aberdeenshire population aged 75 and over is 156%, a change from around 16,500 to 42,3002. This is the greatest projected rise in Scotland2. Figure 27: Population projections for the 75 and over age group in Grampian2 Number of people aged 75+ Population projections for the 75 and over age group in Grampian 90,000 80,000 70,000 60,000 50,000 40,000 30,000 20,000 10,000 0 2006 2011 2016 2021 2026 2031 Source: GROS, 2009 This predicted rise in the population of older people has considerable implications for the provision of health and social care within Grampian. This is because older people have considerable needs for health services and are high users of health services. Furthermore, once admitted, patients in this age group typically have a longer length of stay in hospital compared to other age groups. In addition, the predicted decline in birth rate will shift the balance of the population of working age compared to the dependent population. Thus the proportion of people likely to be economically active in relation to the proportion of people more likely to be supported by the state will change. As with much of the UK, the dependency ratio (i.e. the number of people aged 16-64 per person aged over 65) across Grampian is likely to drop. This will 44 result in less people of working age being available to care for and support older people. It is estimated that almost 40% of health and social care spending across Scotland is on caring for people aged over 65 years old45. Mortality The causes of mortality in this age group are reflected in the most frequent causes of mortality figure (table 11). The majority of deaths occur in this age group12. Of the 5317 deaths in Grampian in 2008, 81% were in those aged 65 years and over with 62% of deaths in those 75 years and over7. As is reflected in these tables, deaths due to pneumonia, cerebrovascular disease and dementia are increasingly common in this age group7. Morbidity In Scotland, a significant proportion of individuals over the age of 65 have long term health condition with many individuals having multiple medical conditions. Individuals in this age group may increasingly have mobility problems or pain not captured in routinely collected data. However, the 2007/08 Scottish Household Survey data suggests that around 52% of women and 48% of men over 70 years in Scotland have a long-standing illness, health problem or disability46. Despite this the majority of this population report their health to be ‘fairly good’. This may reflect nonlimiting illness however it may also be a reflection of the expectation of poorer health with increasing age46. The proportion of those reporting ‘good’ health contrasts with the 16-44 year old population where between 65% and 68% report ‘good’ health46. Figure 28: Self-perception of health by age group46 Source: Scottish Household Survey 2007/2008 report The leading causes of disability in this age group include hearing loss, arthritis, disorders of vision and dementia. Ischaemic heart disease, chronic obstructive pulmonary disease and cerebrovascular disease are also significant causes of disability29. Hospital admissions In 2007/2008 there were 45,004 discharges from hospitals in Grampian for patients aged 65 and older47. This accounts for 40% of the 111,620 admissions within 45 Grampian47. The most common conditions resulting in admission were diseases of the circulatory system (18%) followed by neoplastic disease (14%) 47 and a significant number of these admissions were emergency admissions. In 2007/2008, there were about 18,725 emergency admissions in those aged 65 years and over. These admissions resulted in 301,660 emergency bed days, averaging 16 days per admission47. The emergency admission rate per 100,000 population for patients aged 65 years with 1 admission in a given year increased from 21,981 in 2007/08 to 22,187 in 2008/09. There has been a slight decrease in this rate to 4,091 in 2008/09. Rates of emergency admissions per 100,000 population were lower in Grampian, Aberdeenshire and Moray than Scotland47. The rate in Aberdeen City was higher than the Scottish and Grampian figures (Figure 29). Figure 29: Trend of Admission Rates per 100,000 Population of All Emergency Admissions for Patients Aged 65+ by Financial Year, Scotland, Grampian and CHP 30,000 Per 100,000 population 25,000 20,000 All Scottish Residents Grampian 15,000 Aberdeen City Aberdeenshire 10,000 Moray 5,000 19 99 /0 20 0 00 /0 20 1 01 /0 20 2 02 /0 20 3 03 /0 4 20 04 /0 20 5 05 /0 20 6 06 /0 20 7 07 /0 20 8 08 /0 9 0 Financial Year Source ISD Scotland, 2009 Among those aged 65 years and over, emergency admission rate increases steadily with increasing age. In 2008/09, the emergency admission rate per 100,000 population was 46,577 in those aged 85 years and over compared to 12, 332 in those aged 65-69 years (figure 30). 46 Figure 30: Admission Rates per 100,000 Population of All Emergency Admissions for Patients Aged 65+ by 5 year age group Grampian 2008/2009 50,000 45,000 per 100,000 population 40,000 35,000 30,000 25,000 20,000 15,000 10,000 5,000 0 65-69 70-74 75-79 80-84 85+ Age-Group Source ISD, 2009 Whilst many of these admissions are necessary on medical grounds there is recognition that increased support in the community and better management of chronic disease may prevent some of these admissions. In preventing these admissions pressure on hospital services may be reduced and there will also be significant benefits to our older residents in terms of less discomfort, improved quality of life and avoidance of hospital acquired infections. 47 Preventing ill health Hospital acquired infections Although hospital acquired infections can affect any age group, due to other health problems and the increased use of hospital services this population can be most vulnerable. The two hospital acquired infections which have become key problems are MRSA and clostridium difficile. Staphylococcus aureus is a bacteria that colonises about 30% of the healthy population generally with no adverse effects48. It can however cause serious infection. Both meticillin-sensitive (MSSA) and meticillin-resistant (MRSA) remain endemic in many UK hospitals and new and more virulent clones are arising in the community48. The annual number of S. aureus bacteraemia reported in Scotland has fallen by 5.9% per year since 2005/200648. The most recent report for the period April - June 2009, shows that the annual number of S.aureus bacteraemia in NHS Grampian has fallen by 5.7% per year since 2005/06. In the second quarter of 2009, the total number of S. aureus bacteraemia cases identified in Grampian was 47; of which 13 were MRSA bacteraemias (28 %) and 34 were MSSA bacteraemias (72 %) a decreased of about 4.1% compared with the same quarter in of 2008 where 49 S. aureus bacteraemia cases were recorded (table 18). Table 18: NHS Grampian Staphylococcus aureus bacteraemia rates January 2006-June 2009 Quarter Jan 06-Mar 06 Apr 06-Jun 06 Jul 06-Sep 06 Oct 06-Dec 06 Jan 07-Mar 07 Apr 07-Jun 07 Jul 07-Sep 07 Oct 07-Dec 07 Jan 08-Mar 08 Apr 08-Jun 08 Jul 08-Sep 08 Oct 08-Dec 08 Jan 09-Mar 09 Apr 09-Jun 09 S aureus bacteraemia (SAB) No Acute Bed Days Occupied AOBDs MRSA per 1000 AOBDs MSSA per 1000 AOBDs 153787 0.182 0.280 0.462 59 150314 0.146 0.246 0.393 51 67 148326 0.108 0.344 0.452 15 39 54 146061 0.103 0.267 0.370 22 36 58 148575 0.148 0.242 0.390 17 40 57 144291 0.118 0.277 0.395 16 36 52 142931 0.112 0.252 0.364 18 35 53 145936 0.123 0.240 0.363 23 30 53 151200 0.152 0.198 0.351 16 33 49 144968 0.110 0.228 0.338 16 36 52 139623 0.115 0.258 0.372 20 31 51 145633 0.137 0.213 0.350 10 38 48 148522 0.067 0.256 0.323 13 34 47 141424 0.092 0.240 0.332 MRSA No MSSA No 28 43 71 22 37 16 SAB per 1000 AOBDs Source: Health Protection Scotland 2009 In 2008, MRSA was an underlying cause of death or contributory factor to death in 214 deaths in Scotland in 2008, the first decrease in these figures since 1996 when 48 only 34 deaths were recorded49. Twenty three (23) of these deaths occurred in Grampian50. Clostridium difficile The main risk factors for clostridium difficile associated disease (CDAD) are prior treatment with antibiotics and increasing age. Around 20% of cases occur in the under 65 age group of which the majority occurred in those aged 50-64 years50. An incidence rate of 1.87 per 1000 acute occupied bed days (AOBD) in those aged 65 and over is compared with 0.85 per 1000 AOBDs in those below this age50. Recent reports have highlighted the need to do more to tackle CDAD in Grampian. The HEAT target, as a minimum, is to reduce the rate of CDAD among patients aged 65 and over by at least 30% by March 2011 from 2007/2008 levels. In contrast to the majority of boards NHS Grampian has not met its interim target51. Table 19: Numbers of cases and rates of CDAD in patients 65 years and older 51 Total cases Rates per 100 total OCBD (elderly) Jan 2009-Mar Jan 09-March 2008 (Oct 07-Sept 2009 09 08) Grampian 203 1.67 1.66 Scotland 1152 0.88 1.29 Source: Health Protection Scotland. CDAD can result in significant discomfort for patients and prolonged hospital stays and these effects should not be underestimated. In a minority of cases it can also cause death or contribute to the death of a frail individual. Clostridium difficile was recorded as either the underlying cause of death or as a contributory factor in 765 deaths in Scotland in 200852. This has increased substantially since 116 deaths were recorded in 200052. Eighty two (82) of these Scottish deaths occurred in Grampian in 2008. Although the increasing number of deaths being seen may be related to higher levels of infection there may also have been a change in the reporting of deaths where patients have evidence of CDAD52. Figure 31: Deaths associated with CDAD in Grampian by year52 Source: GROS, 2009 49 Seasonal influenza Although influenza is generally a mild illness some patients develop serious complication such as pneumonia. Whilst these complications can occur in any age the elderly, very young and those with chronic health problems are most at risk. 76.3% of the 65 and over age group in Scotland in 2008/09 took up the offer of the seasonal influenza vaccine, in excess of targets53. Uptake in Grampian is at a similar level. The uptake in those at risk in the under 65 age group is estimated to be around 48.5%, below the target of 60%53. 50 Diseases of significant concern The following section looks in more detail at some of the diseases which are of significant concern. These diseases are highlighted due to their high contribution to the burden of disease in our population. In some cases this relates to the increasing prevalence of these diseases and the implications for future health care. Cancer36 The number of patients diagnosed with cancer is anticipated to increase substantially over the coming decade. It is projected that during the period 2016 – 2020, there will be, on average, 3689 patients in Grampian diagnosed with cancer each year, an increase of 1106 patients per annum relative to each of the years during the period 2001 – 200554. As seen in the QOF prevalence figures, prevalence in Grampian is comparable to that of the Scottish population31 although there are some cancer types, such as colorectal cancer, for which incidence in our population is above what would be expected55. Table 20: Projected number of cases of cancer in Grampian54 Actual cases Projected number of cases Grampian 2001-2005 2006201120162010 2015 2020 Cases per 5 year period 12917 14841 16517 18443 (Average per annum) (2583) (2968) (3303) (3689) Source ISD 2009 The increase in the numbers of malignancies seen will vary significantly between different groups of cancers. As can be seen in the figure below, large increases are anticipated in some cancers whilst for other cancers the number of new presentations will remain unchanged or fall slightly54. Figure 32: Projected cases per 5 year period by ICD code for Grampian54 Projected cases per 5 year period by ICD code for Grampian Colorectal Breast Lung Prostate Bladder Non-Hodgkin lymphoma Head and Neck Oesophagus Melanoma skin Stomach Renal Ovary Pancreas Leukaemia Corpus Uteri Brain, meninges and CNS Cervix Testis Hodgkin disease Other and unspecified Projected cas es for 2006-10 Projected cas es for 2011-15 Projected cas es for 2016-20 - 500 1,000 1,500 2,000 2,500 3,000 3,500 Projected number of cas es Source ISD Scotland 2009 51 Many cancers are known to be potentially preventable. The World Cancer Research Fund (WCRF) estimates that 26% of all cancers in the UK are attributable to factors including diet, exercise, body fatness and alcohol consumption56. For some specific cancers, the proportion of cases that are potentially preventable within the UK is assessed as being much higher, for example breast cancer (42%), colorectal cancer (43%), stomach cancer (45%), endometrial cancer (56%)56. Furthermore, these estimates did not take smoking into account. Both the risk of cancer and mortality from cancer increases with increasing deprivation although this relationship is not seen for all individual cancer types. Cancers which show this relationship often have modifiable lifestyle risk factors which are more common in deprived communities. Figure 33: European age-standardised incidence (2001-2005) and mortality (2003-2007) rates for cancer in Scotland, by SIMD 2006 deprivation quintile57. All malignant neoplasms excluding non-melanoma skin cancer Age-standardised incidence and mortality rates by SIMD 2006 deprivation quintile, persons Rate per 100,000 500 400 300 Incidence 200 Mortality 100 0 1 (Least deprived) 2 3 4 5 (Most deprived) Deprivation quintile Source ISD Scotland 2009 There is a wide spectrum of care needs amongst those with cancer from those receiving their diagnosis and primary treatment, to those being treated for recurrent disease or those in the terminal stages of the disease. The number of patients surviving cancer in Scotland has improved significantly in recent years and services will increasingly have to meet the needs, both physical and psychological, of this group of patients. During the period 2000 – 2004, five-year relative survival among men and women in Scotland diagnosed with malignant disease (excluding nonmelanoma skin cancer) was 42% and 51% respectively58. This represents a 17% and 13% increase compared to the period 1980 – 198458. Coronary heart disease (CHD) Coronary heart disease encompasses a spectrum of illness from patients with occasional episodes of chest pain or shortness of breath, to those presenting with an acute myocardial infarction. It also includes a group of patients with chronic debilitating symptoms significantly affecting quality of life. Alongside aiming to prevent coronary heart disease from developing, steps can be taken at each stage to reduce symptoms, reduce the risk of progression and death, and improve the quality of life of patients. In Scotland it remains one of the leading causes of death. About 16% of premature deaths in Scotland in 2007 were as a result of coronary heart disease59. 52 Coronary heart disease is a preventable disease and the main risk factors are behavioural. As with many of the diseases which are currently of concern in our population, smoking, obesity, lack of physical activity and poor diet play a role in the risk of coronary heart disease59. Other health conditions which can be treated or prevented in many cases such as high blood cholesterol, high blood pressure and type 2 diabetes mellitus are also strong risk factors59. The proportion of coronary heart disease attributable to the five key modifiable risk factors is estimated to be59; High blood cholesterol (46%) Physical inactivity (37%) Smoking (19%) High blood pressure (13%) Obesity (6%) These estimates from the National Heart Forum reflect that people can have more than one risk factor and a combination of factors often act together to increase risk. Socioeconomic deprivation is also a well recognised risk factor for CHD60. Mortality rates from CHD in the most deprived areas in Scotland are almost double those of the least deprived areas60. For premature deaths the inequality gap is even greater with standardised mortality ratios for the most deprived groups around four times those of the least deprived (SIMD deciles, 2003-2007)60. similar trends are seen in Grampian (figure 34). Figure 34: CHD mortality rates among under 75 year olds in the most deprived 15% areas (SIMD 2006); rate per 100,000 European age-standardised (EASR) 3 year rolling averages 1998-2008 250.0 EASR per 100,000 200.0 150.0 100.0 50.0 0.0 19982000 19992001 Males Scotland 20002002 20012003 Males Grampian 20022004 20032005 Female Scotland 20042006 20052007 20062008 Female Grampian Source ISD Scotland 2009 53 The incidence of, and mortality from, coronary heart disease has been falling in Scotland in recent years although rates remain amongst the highest in western Europe60. Figure 35: Incidence of CHD (from first hospital admission) Source ISD Scotland 2009 Figure 35 and 36 show that the incidence of coronary heart disease has been falling in Grampian and across the CHP areas as has been the trend in Scotland, although this may not be occurring at the same rate60. This data includes only first incidences of hospital admission therefore patient management practices or a population with high turnover, as well as underlying disease incidence, may influence these findings. Figure 36: Trend, Age-sex standardised incidence rate from CHD (Standard European population) per 100, 000 population. CHP, Grampian and Scotland 2000-2009 (all age groups) Rate per 100,000 Population 600.0 500.0 400.0 300.0 200.0 100.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Year (ending 31st March) Aberdeen City Male Aberdeen City Female Aberdeenshire Male Aberdeenshire Female Moray Male Moray Female Scotland Male Scotland Female Grampian Male Grampian Female Source: ISD Scotland 54 Although the incident rate of CHD is falling, the prevalence is much higher, being influenced by both new cases and increasing number of people living with the disease. The crude prevalence of CHD per 100 population is closely related to age and it is highest in those aged 65 years and over. SMR1 data suggests that the crude prevalence rate of CHD per 100 population in Grampian is about 3.15 per 100 compared with the Scottish rate of 3.51 per 100 population. Corresponding estimates for Aberdeen City,, Aberdeenshire and Moray CHP areas are 3.14, 3.03 and 3.50 per 100 population respectively. QOF data suggest that around 4.04 per 100 registered population in Grampian have coronary heart disease, below the Scottish figure of 4.48 per 100 registered31. This is still likely to be an underestimate of the true prevalence of disease. It is estimated that around 8.2% of men and 6.5% of women are living with coronary heart disease in Scotland60. Recent trend show that the mortality rate of CHD is falling in all age groups across Scotland. Similar trends are seen in Grampian and across the three local Authority areas of Grampian. The fall in mortality from coronary heart disease can be attributed in part to improvements in emergency treatment and treatment of risk factors in those with the disease. It is suggested that improvements in these areas account for around 1/3 of the decreased deaths from coronary heart disease61,62. However, around 2/3 of the decreased deaths from coronary heart disease are likely to be due to preventing the disease61,62. The reductions in smoking in particular but also treatments for hypertension and cholesterol are felt to have had the biggest impact63,64. Rate per 1000,000 population Figure 37: Trend, Age-Sex standardised mortality rate from CHD (Standard European Population) per 100, 000 population. CHP, Grampian and Scotland 1999-2008 (all age groups) 350.0 300.0 250.0 200.0 150.0 100.0 50.0 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 Year of death registration Scotland Male Scotland Female Grampian Male Grampian Female Aberdeen City Male Aberdeen City Female Aberdeenshire Male Aberdeenshire Female Moray Male Moray Female Source ISD, Scotland 2009 The importance of preventing coronary heart disease is highlighted by the fact that around 70% of all deaths from acute myocardial infarction occur out of hospital61. Around 40% of those experiencing a first myocardial infarction will die before they reach the hospital61 and for many this will be the first manifestation of coronary heart disease62. Prognosis at 30 days following emergency admission is good with 86% of patients surviving a myocardial infarction and 98% surviving an admission with angina60. Age and sex standardised mortality rates show that rates outcomes in 55 Grampian remain comparable with those of Scotland65. However of those who are admitted to hospital around 30% die within 1 year of their first myocardial infarction61. The percentage of patients surviving for 30 days after an emergency admission for Acute Myocardial Infarction in NHS Grampian hospitals (Aberdeen Royal Infirmary, Dr Grays Hospital, Woodend general hospital) can be found at http://www.indicators.scot.nhs.uk/Trends_Jan_2009/AMI.html 65 Stroke Stroke is a major cause of death in Scotland with mortality rates amongst the highest in Western Europe and more than 5,000 people killed every year66. Stroke is also the largest single cause of severe disability in the Scottish population67. Stroke is predominantly a disease of elderly people with around 75% of first strokes each year being in those over 65 years old67. The single largest risk factor for stroke is age66. Whilst sex (incidence rates are higher for men), family history and race can contribute to the risk of stroke, there are key lifestyle factors and modifiable medical conditions which are also implicated. Smoking, alcohol consumption, poor diet and a lack of exercise all increase the risk of stroke, and high blood pressure and cholesterol are important risk factors66. There is also a clear association between premature mortality from stroke and higher levels of deprivation66. Both the incidence of and mortality from stroke has fallen over time in the Scottish population but the rates remain high compared to most other western European countries. Rates of premature mortality have also reduced by almost half between 1998 and 200766. Figure 38: Trend, Age-Sex Standardised Incidence rate of cerebrovascular disease (by first hospital admission) Grampian, CHP area and Scotland 20002009 66 Rate per 100,000 population 250.0 200.0 150.0 100.0 50.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Year (ending March 31st) Aberdeen City Aberdeenshire Moray Grampian Scotland Source ISD Scotland, 2009 56 As seen in figure 38, the incidence rate of cerebrovascular disease in Grampian and across the three CHP areas is lower than in the Scottish figure and has also fallen over the last 10 years66. Figure 39 shows that mortality rate from stoke has been on a downward trend in Grampian and across the CHP areas. This is in line with national trends. Figure 39: Trend, Age-sex standardised mortality rates from stroke per 100,000 population (Grampian, CHP, Scotland) 2000-2009. Rate per 100,000 population 60.0 50.0 40.0 30.0 20.0 10.0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 Year (ending March 31st) Aberdeen City Aberdeenshire Moray Grampian Scotland Source ISD, Scotland For patients with stroke admitted to hospital as an emergency prognosis at 30 days is improving with 81% of patients surviving66. As can be seen in the figure below 30 day survival in Grampian is comparable to results for Scotland65. One of the most important factors in improving the outcome after a stroke is admission to an organised hospital stroke unit where an 18% reduction in death, 20% reduction in death or insitutional care and 22% reduction in death or dependency can by seen in comparison with a general medical ward67. . 57 Figure 40: Standardised rates (%) of patients surviving for 30 days after an emergency admission for Stroke in NHS Grampian Hospitals 1998-200765 Standardised Rate 30 Days (%) 100 95 90 85 80 75 70 65 60 55 50 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 Year (ending 31st Dec) Standardised Rate 30 Days Upper Control Limit Upper Warning Limit Scotland Crude Rate 30 Days Lower Warning Limit Lower Control Limit The majority of patients will survive a stroke, however although around 30% of those who survive a stroke will be independent within three weeks and 50% by six months a significant proportion will be left with a severe limiting disability66. In the 1999 White Paper ‘Towards a Healthier Scotland', and the Coronary Heart Disease and Stroke Update of 2004, the Scottish government set a target for reductions in deaths from cerebrovascular disease in those aged under 75 year by 50% in the 15 years between 1995 and 2010. Figure 41 below shows progress to date against this target. Figure 41: Age-sex standardised mortality rates (under 75) from stroke per 100,000 population in Grampian 2000-2009: Progress against targets 40.0 Rate per 100,000 Population 35.0 30.0 25.0 20.0 15.0 10.0 5.0 0.0 1995 1996 1997 1998 1999 2000 2001 2002 Male European Age Standardised Rate of Mortality Female European Age Standardised Rate of Mortality Both Sexes European Age Standardised Rate of Mortality 2003 2004 2005 2006 2007 2008 2009 2010 Male Trend to Target Female Trend to Target Both Sexes Trend to Target Source ISD Scotland 2009 58 COPD68 Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease that affects breathing but also causes weight loss, nutritional disturbances and muscle problems. It produces chronic and limiting breathing problems but is also associated with acute exacerbations often related to the increased rate of respiratory infection associated with this disease. Some of these acute exacerbations will require hospitalisation. COPD is also frequently associated with and can contribute to numerous co-existing diseases such as heart disease. COPD is an important cause of morbidity and mortality in Scotland. By far the most significant risk factor for COPD is cigarette smoking. The population attributable risk of COPD from smoking ranges between 50 and 70%. Despite lower rates of smoking the prevalence of COPD and deaths from COPD are continuing to rise, particularly in women, as the rate of COPD may only fall many years after declines in smoking rates. Today’s young and middle age smokers are at high risk of developing COPD in later life unless they can be helped to stop smoking. COPD is primarily a chronic disease managed in primary care or by the patient themselves and the prevalence data from the QOF which, is derived from practice-based disease registers shows that in 2009 the prevalence of COPD in Grampian was estimated to be 1.38 per 100 registered patients compared to 1.8 per 100 registered patients in Scotland. Although this figure is less than the Scottish figure, it still equates to over 7000 patients and it is estimated that as many as two thirds of cases are undiagnosed. Table 21: QOF Prevalence Estimates of COPD in Grampian and CHP QOF COPD prevalence for the year 2007/2008 per 100 patients registered QOF COPD prevalence per 100 registered patients applied to the 2007 General Register Office for Scotland midyear population estimates Aberdeen City CHP 1.37 Individual practices within the CHP: 0.27 – 2.51 2888 Aberdeenshire CHP 1.36 Individual practices within the CHP: 0.70 – 3.29 3300 Moray CHP 1.48 Individual practices within the CHP: 0.89 – 2.56 1199 Grampian 1.38 7387 Scotland 1.8 - Source: ISD, Scotland 2009, NHS Grampian PH Intelligence Team 2009 Nevertheless, it produces a significant burden on secondary care. In 2008, there were over 1800 episodes of acute hospital care due to COPD among Grampian residents (table 22). Over the preceding 5 years from 2008, the number of episodes 59 of care due to COPD involving male patients has remained stable with a slight decline in trend compared with female patients where the number of episodes has remained relatively stable. The majority of these episodes of care due to COPD involve patients aged 65 – 85 years of age. In 2006, the annual number of emergency admissions in Scotland due to COPD was 14,653 and admissions with a principal diagnosis of COPD have risen more than 2.5-fold in the last 25 years. Estimates of bed occupancy levels for Aberdeenshire residents from March 2007 to May 2008 suggested that COPD patients accounted for 22% of occupied beds. Table 22 : Episodes of Care as a Consequence of COPD & Bronchiectasis Grampian Residents Recorded number of episodes of care (2008) Aberdeen City CHP 699 Aberdeenshire CHP 850 Moray CHP 263 Grampian 1812 Source: NHS Grampian PH intelligence Team, 2009 Comparison of UK COPD Audit Data with NHS Grampian data for 2003/04 suggested that readmission rates, 90 day mortality rates following admission and mortality rates on admission were worse than for the UK. A 90 day mortality of 23% was seen and a readmission rate of 47%. The early supported discharge service commenced in 2002/03 and has seen the average length of stay for respiratory wards fall by around 2 days (7 days to 5 days) from 2001./02 to 2005/06. Chronic Kidney Disease (CKD) 69 It is estimated that 5-11% of the population may have evidence of kidney impairment. In the past, very few of these people were identified as having CKD (<0.2% of the population). In Scotland, there are estimated to be in excess of 200,000 people who until recently were undiagnosed and unknown to services. People with CKD are at an increased risk of kidney failure (end stage kidney disease) requiring some sort of replacement therapy (dialysis) or transplant. As with individuals who have diabetes they are also at increased risk of other diseases, particularly cardiovascular disease and cardiovascular death. In population studies in Norway, >20% of people with evidence of stage 3 disease died of a cardiovascular event within 8 years. In England, screening for CKD is part of the vascular risk screening programme currently being discussed. In the last 5 years, a number of developments have led to greater awareness and diagnosis of CDK. In Grampian, the introduction of new national lab reporting methods coincided with a 50% increase in new referrals for CKD. Whilst these patients are being identified there is still much that we do not know about their management. A substantial, and as yet poorly defined, sub group of people labelled with CKD will experience no health consequences of their impaired kidney function. At what point the benefits of labelling and actively managing someone with CKD 60 outweigh the harms of investigations and treatments is a challenging clinical decision. Diabetes 70 The most recent Scottish Diabetes Survey (2008) estimated that around 4.3% of the Scottish population had a diagnosis of diabetes at the end of 2008, with prevalence ranging between 3.8% and 4.7% between NHS Boards. A prevalence of 4% of the population was found in Grampian. These estimates are somewhat higher than the QOF prevalence figures but both show prevalence in Grampian to be below that of Scotland. A clear majority of disease, 87%, was attributable to type 2 diabetes. Although the causes of both type 1 and type 2 diabetes are not fully understood it is clear that much type 2 disease is potentially preventable. Prevalence in Scotland is increasing rapidly as in many other countries. Although this is influenced by increased awareness of the disease, more complete recording, and an increasingly elderly population, poor diet and low physical activity are also contributing with overweight and obesity key risk factors. The Scottish Diabetes Survey found that 33% of patients with a recorded BMI were overweight, with 50% of patients obese. Prevalence of diabetes also rises with deprivation. The odds of having type 2 diabetes is 77% higher among the most deprived compared with the most affluent. Diabetes mellitus is an important cause of disability and is associated with increased risk of other key diseases, including coronary heart disease, cerebrovascular disease and renal failure. For example, the Scottish Diabetes Survey found that 9.5% of diabetes patients had had and survived a myocardial infarction. Whilst the disease itself can be prevented, good diabetic control, management of risk factors for associated disease, and early detection of complications such as diabetic eye disease is important in reducing disability and mortality. Mental Health Mental health problems Mental health problems occur at significant levels in our population often resulting in disability for individuals affected and an increasingly recognised burden to society. It is predicated that depression will be in second place as an international health burden by 2030 behind only HIV and AIDS. Capturing the extent of these problems with routinely collected data is difficult. Not only are the majority of mental health problems managed in the community, a significant proportion of illness will not present to the health service. Community surveys estimate that neurotic disorders including depression, anxiety disorders and obsessive compulsive disorder affect around 15% of the population, with prevalence higher in the female population71. It is estimated that 5.8% of men and 9.5% of women will experience a depressive episode in any given year 71. Prevalence of probable psychotic disorders is estimated at around 5 per 1,000 population aged 16-74 years71. 61 Figure 42: Rates of neurotic disorder by subcategory71 In 2007/08, there were a total of 23,377 psychiatric admissions in Scotland. Of this 1733 were in Grampian. Table 23 below shows the corresponding figures for the CHP areas during the same period. Table 23: Admissions to mental illness specialities in Grampian hospitals by type of admission 2007/2008 Total 819 Aberdeen City 638 Aberdeenshire 298 Moray 1 755 Grampian 23 377 Scotland Source ISD, Scotland 2009 1st admission 226 244 91 561 6 930 Readmission 512 345 178 1 035 13 542 transfer 76 47 27 150 2 252 others/not known 5 2 2 9 653 Suicide itself is a leading cause of mortality among young people72. Scotland’s suicide rate is higher than in other parts of the UK with 843 deaths from suicide in 200872. Suicide rates in men are around three times those seen in women72. Rates in Grampian are below those for the Scottish population, with rates in the female population significantly lower72. Suicide rates increase with increasing deprivation, almost doubling between the least and most deprived areas in Scotland72. Mental Wellbeing There is increased interest in the full spectrum of mental health including mental wellbeing, or positive mental health73. This captures features such as life satisfaction, purpose and positive relationships and is influenced by broader societal attributes as well as individual factors73. Good mental wellbeing is recognised as enabling people to realise their potential, fulfil social roles and in turn adds to societal welfare73. The Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS) and the life satisfaction score have been developed to assess this. In 2006 the mean WEMWBS score for the adult Scottish population was 51 (scale 14 to 70) with 14% of those surveyed having “good” mental health, 73% “average” mental health, and 14% “poor” mental health74. The mean life satisfaction score amongst adults in 2006 was 7.4 on a scale of 0 to 10, with 10 being extremely satisfied74. This has not changed significantly since 200274. There is some evidence from this survey that mental wellbeing is improved among those receiving a higher income, in those with good health and in those who have had no experience of psychiatric disorder74. 62 Protecting the health of the population Health Protection is now the accepted term to describe the work that encompasses the surveillance, investigation, control and prevention of communicable disease and environmental hazards to human health. NHS Grampian works closely with the three Local Authorities and other partner agencies to deliver services to protect the health of the Grampian population. We see some infections regularly, although the numbers do vary from year to year (see Table 24). Grampian continues to have one of the highest rates of gastrointestinal infections in Scotland i.e. infections caused by Campylobacter, Salmonella, Cryptosporidium and E coli O157. Some of these infections are the result of our lifestyles. For example, risky behaviours known to be associated with these and other bacteria are contact with animals, the use of untreated or poorly maintained private water supplies, poor hand washing after handling raw food and travel abroad. The higher number of cases of some gastrointestinal infections e.g. E coli O157 infection may be attributed to the increased exposure to animal faeces that may occur in a rural location with a large number of cattle and sheep combined with a large number of households on poorly treated and maintained private water supplies, especially in Aberdeenshire. Many of these infections show a seasonal pattern. For example we see an increase in reports of Salmonella and Campylobacter infections in the summer months possibly associated with travel abroad and outdoor living. The numbers of E coli O157 infections tend to increase in August and September, especially after heavy rain Figure 43 E Coli o157 2005 to 2010 Monthly EColi 0157 2005 to 2010 18 16 14 12 2005 2006 2007 2008 2009 2010 10 8 6 4 2 0 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 63 Table 24 Number of cases of reported and notified communicable disease in Grampian in 2005 - 2009 Disease Dysentery Botulism Campylobacter Chickenpox Diphtheria Erysipelas Food poisoning: Total Aeromonas* Cryptosporidium* E coli O157* Entamoeba histolytica * Giardia* Salmonella* Yersinia* Vibrio parahaemolyticus* Legionellosis Leptospirosis Lyme Disease# Malaria Measles Meningococcal infection Mumps Q Fever Rubella Scarlet fever TB respiratory TB non respiratory Typhoid Hepatitis A Hepatitis B (acute) Hepatitis B (chronic) Hepatitis C Whooping Cough 2005 2006 2007 2008 2009 23 0 668 1887 0 1 428 87 100 45 0 23 134 30 1 5 0 1 14 7 12 570 0 13 21 16 9 0 1 6 28 125 4 9 1 648 2016 0 0 397 73 83 54 4 17 138 20 0 1 2 12 7 14 13 271 1 14 23 25 13 1 1 4 29 130 9 13 0 664 2283 1 2 386 87 67 55 4 12 135 25 0 2 1 53 12 5 11 145 0 14 22 20 22 0 2 1 43 124 16 12 0 665 1464 0 0 398 91 79 56 6 17 127 21 0 1 0 65 12 4 12 37 0 5 19 17 22 0 2 1 63 136 20 6 0 801 1697 1 1 401 85 107 57 4 17 105 26 0 2 0 49 12 4 10 81 0 5 28 27 23 0 3 3 60 124 15 Notes * These infection are included in Food Poisoning figures # The apparent increase in Lyme disease reflects a change in reporting by the laboratory. Figures are based on clinical notifications and laboratory isolated organisms. 64 Outbreaks of gastrointestinal infections These figures are derived from the Health Protection Scotland (HPS) ObSurv surveillance system for general outbreaks of intestinal diseases in Scotland and are by date of report to HPS. Table 25 Number of outbreaks of gastrointestinal infection by date reported to Health Protection Scotland 2005-2009 Pathogen 2005 Campylobacter 0 C. perfringens 0 E.coli 2 Norovirus 25 Rotavirus 0 Salmonella 0 Scombrotoxin 0 Shigella sonnei 0 Staph. aureus 0 Unknown 4 Viral 1 Total 32 * 2009 data is still provisional 2006 0 1 2 34 1 1 0 0 0 2 0 41 2007 1 1 2 38 0 0 0 1 0 2 0 45 2008 0 1 1 41 0 0 1 0 0 1 0 45 2009* 0 0 1 47 0 0 0 0 1 0 0 49 Norovirus is the commonest cause outbreaks of gastrointestinal infections in Grampian - 85% (185/218) of all reported outbreaks. These outbreaks affected an estimated 4502 individuals between 2005 -2009 and Table 26 shows location of the outbreaks. Table 26 Location of outbreaks of Norovirus infection reported by NHS Grampian Location Hospital Residential Institution Hotel Restaurant School Armed services camp Other 2005 11 11 0 0 2 0 1 2006 7 18 2 1 1 0 5 2007 20 17 0 0 0 1 0 2008 20 11 3 1 4 0 2 2009 9 30 3 2 3 0 0 A total of 1780 (40%) cases were reported in residential institutions and 1874 (42%) cases were reported in hospitals. Immunisation and vaccine preventable diseases Immunisations are the most effective and economical way of reducing the burden of morbidity and mortality associated with serious infectious disease in children. Apart from its protective effect in an individual child, immunisation produces an indirect effect known as ‘herd immunity’. Herd immunity occurs when a high proportion of the population have been vaccinated. This reduces the opportunity for specific infections to circulate in the community, thereby protecting those children who remain unvaccinated. To ensure herd immunity 95% of the eligible population usually need to be immunised against each disease. 65 Description of the UK immunisation programme The programme is extensive and complex and comprises: Vaccination against 10 diseases (Diphtheria, Tetanus, Polio, Whooping Cough, Haemophilus influenzae type B (Hib), Meningococcal C (MenC) infection, Pneumococcal infection (PCV), Measles, Mumps, Rubella) to all children. Hepatitis B and BCG (TB) vaccination are offered to selected children based on risk assessment Human Papilloma Virus vaccination is offered to all teenage girls up to 18 years of age Pneumococcal and seasonal flu vaccination is offered to individuals aged less than 65 years who are at increased clinical risk and to all adults aged 65 years or more. Protection against each disease requires one or more doses of vaccine (given at specific intervals) to establish initial immunity, with some diseases requiring further booster doses of vaccine to maintain immunity throughout life. . Vaccine uptake results- Overview of 2009/2010 The uptake of childhood immunisation is the proportion of children who have received an appropriate vaccine for their age. Generally, uptake rates for all immunisation remains high in Grampian compared with the Scottish average. Summary uptake figures for children reaching ages 12 months, 24 months and five years in financial year ending 31 March 2010 in Grampian are shown in the tables and figures below. Table 27: Uptake of Diphtheria, Tetanus, Pertussis, Polio and Hib by 12 months of age in Grampian 1 April 2009 to 31 March 2010 Area Aberdeen City CHP Aberdeenshire CHP Diphtheria Tetanus Pertussis Polio Hib MenC PCV 97.1 97.1 97.1 97.0 96.9 95.4 95.9 98.6 98.6 98.6 98.6 98.5 97.9 98.1 Moray CHCP 97.6 97.6 97.6 97.5 97.6 97.1 96.9 Grampian 97.8 97.8 97.8 97.7 97.6 96.6 96.9 97.4 97.4 97.4 97.4 97.3 97 97.2 Scotland Source: ISD 66 Table 28: Uptake of Diphtheria, Tetanus, Pertussis, Polio and Hib by 24 months of age in Grampian by CHP area, 1 April 2009 to 31 March 2010 Primary course Booster course D T P Pol Hib Men C Aberdeen City CHP 98. 6 98. 6 98. 6 98. 6 98. 0 94.5 Aberdeenshire CHP 99. 1 97. 9 98. 7 98. 4 99. 1 97. 9 98. 7 98. 4 99. 1 97. 9 98. 7 98. 4 99. 0 97. 9 98. 7 98. 4 98. 8 97. 9 98. 3 98. 2 Moray CH&SCP Grampian Scotland Source: ISD, 2010 96.9 96.7 95.9 96.4 PC V 95. 4 MMR Hib/Me 1 nC 97. 3 96. 7 96. 4 96. 5 PCV B 95.5 93.9 94.3 95.0 95.5 95.1 95.4 95.3 95.7 95.2 94.8 94.8 93.7 94.0 94.2 Table 29: Uptake of Diphtheria, Tetanus, Pertussis, Polio and Hib by 5 years of age in Grampian by CHP area, 1 April 2009 to 31 March 2010 D Aberdeen City T Primary course P Pol Hib MenC D Booster course T P Pol 97.6 97.6 97.6 97.6 95.8 94.4 93.5 93.5 93.5 93.5 Aberdeenshire 98.5 98.5 98.3 98.4 97.8 97.4 94.9 94.9 94.9 94.9 Moray 98.1 98.1 98 98.1 97.7 97.4 95.9 95.9 95.9 95.9 Grampian 98.0 98.0 97.9 97.9 96.9 96.1 94.4 94.4 94.4 94.4 Scotland 98.4 98.4 98.4 98.3 97.4 Source ISD 2010 97.4 91.9 91.9 91.9 91.9 Primary Immunisation Uptake rate by Deprivation Across Scotland, there are noticeable differences in uptake as children age, and this appears to be closely related to deprivation. Children in more deprived areas appear to be vaccinated at a later age compared with children in the less deprived areas (ISD, 2010) However, whilst there remains significant variation between individual general practices in Grampian, data on uptake of vaccination by deprivation (January to December 2009) shows overall uptake of primary vaccinations by 12 months old to be highest in the most deprived areas in Grampian (SIMD 1). This reflects the effort 67 being made by health visitors and local general practices to encourage high uptake across all social groups. Figure 44: Uptake of Immunisation by Deprivation Diphtheria1,3 uptake by 12 m onths by SIMD category Evaluation period: January to Decem ber 2009 Grampian Scotland % Uptake 98.1 96.8 97.3 96.9 97.7 97.5 97.6 97.9 97.4 90 98.0 100 80 70 60 50 5 4 Le a s t de priv e d 3 SIMD Category 2 1 M o s t de priv e d Uptake of HPV vaccine In November 2007 the Scottish Government confirmed a universal HPV immunisation programme for girls aged 12-13 years would commence in September 2008. Alongside the school based programme, a 3 year phased catch-up programme for older girls aged 17-18 years was also commenced. The HPV vaccine is administered as a 3 dose schedule usually within 0-6months. To be fully immunised, girls must receive all 3 doses. HPV year 1 Available data show the uptake of HPV in Grampian schools has been generally high. For year 1 of the programme, 91.7% of all girls in S2 received 3 doses of the vaccine compared to 91.4% across Scotland. Similar high uptake rates were observed within the 3 CHP areas in Grampian (figure 45). This is higher than the 80% uptake rate required to make the programme cost effective. 68 Figure 45: Uptake of HPV Immunisation for Girls in S2 in Grampian by CHP Year 1 (2008/2009) 93.6 91.4 94.4 93.7 91.7 94.5 95.1 93.3 95.8 94.4 92.6 95.2 89.7 93.0 100 90 80 70 60 50 40 30 20 10 0 92.1 Percentage uptake HPV Immunisation Uptake rates for girls in second year of secondary school (S2) Year 1 (2008/2009) as at 15 February 2010 Aberdeen City CHP Aberdeenshire CHP Moray CH&SCP Grampian Scotland 1st dose 2nd dose 3rd dose ISD 2010 However, uptake rate for girls in the catch-up category, especially those who are out of school has been less successful. There are significant differences in uptake between girls in secondary school and those who have left school. Table 30 shows the uptake rate in all girls in the catch–up cohort, eligible for immunisation during year 1 of the programme. These are girls in S5, S6 during the school year 2008/09 and girls aged 16 to less than 18years on 1 September 2008 who have left school. Table 30: Uptake of HPV Immunisation in Girls eligible for catch-up vaccination in Grampian (year 1) Uptake of HPV Immunisation in Girls in the catch-up Cohort September 2008 – August 2009 (Year 1 of the catch-up). Completed doses of HPV vaccine Percentage of all girls eligible for catch-up vaccination in 2008/09 who have been vaccinated Percentage of girls in S5 who have been vaccinated Percentage of girls in S6 who have been vaccinated Grampian Grampian Grampian (Scotland) (Scotland) (Scotland) 68.1 (70.9) 94.4 (94.6) 92.6 (93.0) First dose 65.2 (67.7) 93.2 (93.5) 92.0 (91.8) Second dose 55 (59.7) 90.1 (89.9) 88.5 (86.6) Third dose ISD statistics for year 1 of the HPV programme (Sep 2008-Aug 2009) Percentage of girls out of school who have been vaccinated Grampian (Scotland) 43.5 (48.5) 38.6 (43.4) 21.9 (31.8) 69 As of 15 February 2010, uptake rate for all three doses in the catch-up cohort was generally low in Grampian (43.5%, 38.6% and 21.9% respectively) compared to Scottish average (48.5%, 43.4% and 31.8% respectively). Uptake for girls in the catch-up group in Grampian who had left school were significantly lower (21.9%) compared to uptake rates in girls in the catch-up cohort in S5 (90.1%) and S6 (88.5%). Similar low uptakes were recorded within the 3 CHP areas (table 46 and figure 47). Figure 46: Uptake of HPV Immunisation in Girls eligible for the catch-up vaccination in year 1 (2008/09) in Grampian by CHP area HPV Vaccine uptake in school leavers catch-up cohort by CHP Year 1 (2008/09) as at 15 Feb 2010 80 31.8 43.4 48.5 21.9 38.6 43.5 22.2 45.8 25.2 42.0 47.4 18.1 36.3 40 20 50.8 60 32.0 Percentage uptake 100 0 Aberdeen City CHP Aberdeenshire CHP Moray CH&SCP 1st dose 2nd dose Grampian Scotland 3rd dose ISD statistics for year 1 of the HPV programme (Sep 2008-Aug 2009) HPV year 2 Based on data recorded on the CHI system as at 30th June 2009 and SIRS system as at 15 February 2010, uptake of routine HPV immunisation in girls currently in S2 for the second year of the programme continues to remain exceptionally high in Grampian; 92.1% for the first dose and 89.2% for the second dose. Similar high uptake rates are observed within the 3 CHP areas in Grampian (figure 47). These uptake rates are likely to increase especially for the second dose as some girls may have started their course of the HPV vaccinations later in the school year. It is also possible that some vaccinations may have been given but have not yet been recorded on CHSP. 70 Figure 47: Uptake of HPV Immunisation for Girls in S2 in Grampian by CHP Year 2 (2009/2010) HPV Vaccine Uptake for Girls in S2 in Grampian by CHP Year 2 (2009/10) as at 15 Februrary 2010 85.8 91.9 89.2 92.1 88.1 90.7 89.6 93.0 89.4 90 80 70 60 50 40 30 20 91.7 Percentage uptake 100 10 0 Aberdeen City CHP Aberdeenshire CHP Moray CH&SCP 1st dose Grampian Scotland 2nd dose A more detailed report of the performance of immunisation services within Grampian will be available in November 2010. Tuberculosis (TB) Cases of Tuberculosis have continued their upward trend, rising from 24 in 2004 to 50 Grampian residents diagnosed with TB disease during 2009. Locally, over the last 3 years, 72% of cases occurring in Grampian have been in people with a non-UK country of origin. The majority of these individuals have developed symptoms of active TB disease some 2 -3 years (or more) following arrival in Grampian and it is likely this represents reactivation of long-standing latent infection. In response to this increase in TB incidence, a local initiative has been established to offer more accessible TB screening to new entrants coming from selected high TB incidence countries. During 2010, the Grampian Tuberculosis Policy has been revised to take account of Scottish Guidance on prevention and management of TB published in 2009. A Scottish TB Action Plan is being developed nationally with anticipated publication in 2011 and this will inform future local action. A more detailed report about TB in Grampian will be available in December 2010. 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