Tentative Scientific Programme
30th November 2010 (Tuesday)
Time
Venue
13:00
-
Registration
G/F Exhibition Hall
18:30
JHF Workshop on Alliance of Patient Advocates
Chair: Stephen Lam, Fernando Cheung
W 1.1 Christina Hellmann
How to raise and take care of a child with Orphan Disease
W 1.2 Kin-Ping Tsang
14:30
Medical Genetics and Patients’ Engagement
-
G/F Pao Yue Kong Auditorium
W 1.3 Min-Chieh Tseng
16:30
Advocacy and Services for the Patients in Taiwan: The Case of Taiwan Foundation for Rare Disorders
W 1.4 Stephen Ma
Mucopolysaccharidosis and Rare Disease Mutual Support Group
W 1.5 Ysbrand Poortman
Patient/parent/family organizations and their (potential) role in care and prevention of chronic/genetic conditions
16:30
Coffee Break
G/F Exhibition Hall
HKUCHM Workshop on Communication and Counselling “ Advice Giving in Genetic Counselling”
Chair: Angus Clarke, Chin-Peng Lee
W 2.1 Srikant Sarangi & Kristina Bennert
16:45
18:30
Warrants for Advice-giving in Genetic Counselling
W 2.2 Olga Zayts & Stephanie Schnurr
“You may know better than I do when it comes to medical thing”: Client’s Elicitation of Advice in Prenatal
Genetic Counselling in Hong Kong
W 2.3 Tina-Marie Wessels
“You to decide what is best for you” – Advice Giving during Decision-making in Intercultural Antenatal Genetic
G/F Pao Yue Kong Auditorium
Counselling Sessions
W 2.4 Angus Clarke
Discussion: Advice-giving in genetic counselling
Affymetrix Workshop
W 3.1 Brynn Levy
New Frontiers in Clinical Cytogenetic Diagnosis in Reproductive Medicine & Pediatrics – The Microarray Era
G/F Lim Por Yen Lecture Theatre
W 3.2 Robert Klein
Cancer Clinical Diagnostic Applications with Microarrays: Virtual Karyotyping with SNP Arrays
18:30
20:30
Welcome Reception
G/F Exhibition Hall
1st December 2010 ( Wednesday)
Time
Venue
7:30
-
Registration
G/F Exhibition Hall
18:00
Opening Ceremony
8:00
8:30
Stephen Lam – Chairman, Organizing Committee
Carmen Padilla – President, Asia Pacific Society of Human Genetics
1/F Run Run Shaw Hall
Ivan Lo – Chairman, Hong Kong Society of Medical Genetics
York Chow – Secretary for Food and Health
Plenary Session 1
Chair: Carmen Padilla, Tai-Fai Fok
PL 1.1 Richard Cotton
8:30
Progress in Human Variome Project
-
1/F Run Run Shaw Hall
PL 1.2 Huan-Ming Yang
10:15
Sequencing Technology and Medicine in the 21st Century
PL 1.3 Wai-Yee Chan
Epigenetic Regulation of Non – coding RNA in Health and Diseases
10:15
Coffee Break
G/F Exhibition Hall
Symposium 1 : Human Genome Variation
Chair: Richard Cotton, Larry Baum
S1.1 Ming Qi
Human Variome Project: China Database
10:45
S1.2 Zilfalil Alwi
-
1/F Run Run Shaw Hall
Malaysian Human Genome Variation Project: On the Move
12:30
S1.3 Wan-Ling Yang
Data Analysis in the Era of Genomic Studies and Next Generation Sequencing
S1.4 Larry Baum
Genome Wide Association Studies of Epilepsy
Symposium 2: New Technology and Impact
Chair: Richard Choy, Sumio Sugano
S2.1 Hannah Hong Xue
Inter-Alu next generation sequencing (IAN): a new method for genome-wide detection of hot-spot mutations
S2.2 Sumio Sugano
G/F Pao Yue Kong Auditorium
Human Transcriptome Analysis Using Second Generation Sequencer
S2.3 Richard Choy
Diagnosis of Chromosomal Abnormalities : The Application and Use of Microarray Technology
S2.4 Gary Lu
On the way to detect High Risk Cytogenomic Markers in Plasma Cell Myeloma more accurately
Symposium 3: Epigenetics and Proteomics
Chair: Wai-Yee Chan, Brian Chung
S3.1 Chia-Lin Wei
Dynamic of Genome Organizations and Epigenetic Networks during Pluripotent Cells Differentiation
S3.2 Yi-Jun Ruan
G/F Lim Por Yen Lecture Theatre
Chromatin Interaction and Transcription Regulation
S3.3 Suet-Yi Leung
New Insight into Genetic and Epigenetic Mechanism Causing the Lynch Syndrome
S3.4 Benjamin Yung
Understanding of Molecules and/ or Biomarkers in Cancer
Free Paper Session 1: Reproductive Genetics
Chair: Mary Tang, Terence Lao
FP1.1 Bei Jia
Screening for Chromosomal Abnormalities in 1645 Infertile Couples Undergoing Assisted Reproductive
Technology
FP1.2 Hua Hu
Prenatal Diagnosis of a Pregnant Woman with Mosaics Karyotype
FP1.3 JM Wang
2/F Function Room
Proteolipid Protein 1 (PLP1) Gene Mutations in 33 Chinese Patients with Pelizaeus-Merzbacher Disease and
Prenatal Diagnosis of Five Fetuses in Three Families with PMD Probands
FP1.4 Li-Yan Li
Analysis of Prenatal Diagnosis Results of 206 Thalassemia Families
FP1.5 Shan-Wei Feng
Study on Actively Full Range Management and Service of Population Based Birth Defect Intervention Model
12:30
-
Industrial Lunch Symposium (Beijing Genomics Institute – Hong Kong Ltd.)
1/F Run Run Shaw Hall
13:30
13:30
Poster Session
1/F Foyer
Presidential Address
Chair: Pornswan Wasant
1/F Run Run Shaw Hall
Carmencita D. Padilla
14:00
Medical Genetics in Asia – Pioneering Efforts, Now and the Future
-
Plenary Session 2:
15:45
Chair: Xue Zhang
PL 2.1 Li Jin
1/F Run Run Shaw Hall
PL 2.2 Lin He
GWAS of Complex Disease in the Chinese Population
15:45
Coffee Break
G/F Exhibition Hall
Symposium 4: Genetics in Populations
Chair: Albert Lam, Kwang-Jen Hsiao
S4.1 Kwang-Jen Hsiao
16:15
Tetrahydrobiopterin Synthesis Deficient Hyperphenyl-alaninemia in East Asian
-
1/F Run Run Shaw Hall
S4.2 Hui-Jun Yuan
18:00
Realizing the Promise of the HGP - Identification of Genes Underlying Hereditary Hearing Loss among Chinese Population
S4.3 Nelson Tang
Genome-wide Genotypes Provide New Insights into Population Genetics and Disease Susceptibility
S4.4 Lee Schulman
The Role of CA-125 and Ultrasound in the Management of Women at Increased Risk for Epithelial Ovarian Cancer
Symposium 5 : Complex Diseases
Chair: Lin He, Juliana Chan
S5.1 Juliana Chan
Diabetes and Co-Morbidities - Using Genomics to Unravel Multicausality
S5.2 Maria Merce Garcia-Barcelo
G/F Pao Yue Kong Auditorium
Genetics of Congenital Anomalies
S5.3 Pak Sham
From GWAS to Risk Prediction
S5.4 Chris Lau
The Contrasting Roles of the Sex Chromosomes in Gender Disparity in HBV-associated Hepatocellular Carcinoma
Symposium 6: Thalassemia
Chair: Hai-Yang Law, Suthat Fucharoen
S6.1 Suthat Fucharoen
Thalassemia in Asia: An Overview
S6.2 Vivian Chan
G/F Lim Por Yen Lecture Theatre
Prevention and Control of Thalassemia
S6.3 Victor Boulyyankov
Thalassemia and other Haemoglobinopathies: Emphasizing WHO Approaches to their Prevention and Control
S6.4 Philippe Leboulch
Gene Therapy for Human β-Thalassemia
Free Paper Session 2: New Technologies and Impact
Chair: Shee-Ping Yip, Ronald Wong
FP2.1 Tiong-yan Tan
2/F Function Room
YPEL1 in Craniofacial Development and the Distal 22q11.2 Syndromes
FP2.2 Albert Lam
Subtelomeric Aberrations in Hong Kong
FP2.3 P Liu
Different Genomic Rearrangements can be Associated with Copy Number Variation of the PMP22 Gene in
CMT1A and HNPP
FP2.4 Xiong Li
Study on the Diagnosis of Chromosome Number Aberration by STR Using DHPLC Technology
FP2.5 Hong Jiang
Transglutaminase 6 Identified as a Novel Causative Gene of Spinocerebellar Ataxias Using Exome Sequencing
18:00
19:00
The Asia Pacific Society of Human Genetics (ASPHG) General Meeting
G/F Pao Yue Kong Auditorium
2nd December 2010 (Thursday)
Time
Venue
7:30
-
Registration
G/F Exhibition Hall
19:00
Plenary Session 3
Chair: Grace Tang, Meow-Keong Thong
PL 3.1 Dennis Lo
8:00
Noninvasive Fetal Genetics Analysis from Maternal Plasma
-
1/F Run Run Shaw Hall
PL 3.2 Edison Liu
9:45
Cancer Genome: What Can Be Learned
PL 3.3 Takeyori Saheki
Treatment for Citrin Deficiency Based on the Analysis of the Model Mice
9:45
Coffee Break
G/F Exhibition Hall
Symposium 7: Prenatal Diagnosis
Chair: Mary Tang, Tze-Kin Lau
S7.1 I.C. Verma
Prenatal Diagnosis in India - Current Status and Future Challenges
10:15
S7.2 Tze-Kin Lau
-
1/F Run Run Shaw Hall
Screening for Chromosomal Anomalies by First Trimester Biochemical and Ultrasound Markers
12:00
S7.3 Chin-Peng Lee
Prenatal Diagnosis and Treatment of Homozygous Alpha-Thalassemia in Hong Kong: Development and Challenges
S7.4 Yi-Bin Guo
The Prenatal Gene Diagnosis of 7 Kinds of Hereditary Bone Diseases
Symposium 8: Cancer Genomics
Chair: Lee Schulman, Samuel Kwok
S8.1 Judy WC Ho
Colorectal Cancer Screening – the Role of a Regional Registry
S8.2 Ava Kwong
G/F Pao Yue Kong Auditorium
Hereditary Breast and Ovarian Cancer: The Asia Experience
S8.3 Eva Cutiongco-de la Paz
Genetic Polymorphisms in CYP1A1, GSTM1, GSTP1, GSTT1, NAT1 and NAT2 and Oral Cavity Cancer Risk among Filipinos
S8.4 Kit-Fai Wong
The Promise and Peril of Blood Cancer Cytogenetics
Symposium 9: AASPP Symposium on Citrin Deficiency
Chair: Yoshiyuki Okano, Pik-To Cheung
S9.1 Keiko Kobayashi
SLC25A13 Mutations/ Variations in Citrin Deficiency: Frequency and Distribution
S9.2 Okano Yoshiyuki
A Dynamic Change of Clinical Manifestation by Age in Citrin Deficiency
S9.3 Yuan-Zong Song
Molecular, Cellular, Scientigraphic and Clinical Analysis of a Citrin -deficient Cohort: Experience in a Chinese Pediatric
Centre
S9.4 Masahide Yazaki
Therapeutic Approaches for Patients with Adult-onset Type II Citrullinemia (CTLN2)
S9.5 Paul Hwu
Newborn Screening for Citrin Deficiency
G/F Lim Por Yen Lecture Theatre
Free Paper Session 3: Diagnostics, Screening and Public Health Genetics
Chair: Albert Chan, Priscilla Poon
FP3.1 Teguh Haryo Sasongko
Novel Mutations in 21 Patients with Tuberous Sclerosis Complex and an Exon Skipping Induced by Intraexonic
Deletion of TSC2 Exon 16
FP3.2 Xue-Jiao Qin
Genetic Confirmation of Thiel-Behnke Corneal Dystrophy in Two Large Chinese Families and Suggestion of a
2/F Function Room
Founder Effect
FP3.3 Edgar Hau
Huntington Disease in Hong Kong – Genetics Perspectives
FP3.4 Li-Guang Ma
Research on Chinese Human Genetic Resources Information Management and Sharing
FP3.5 David Chan
Is Chromosome Study Needed in the Evaluation of Hypospadias?
12:00
-
Industrial Lunch Symposium (Agilent Co. Ltd.)
Stephen Laderman
13:00
Advanced Genomics Measurement Technologies for Personalized Medicine
13:00
Poster Sessions
1/F Run Run Shaw Hall
1/F Foyer
Plenary Session 4
Chair: Ishwar Verma, Ivan Lo
PL 4.1 Angus Clarke
13:30
Developments in Understanding Rett Syndrome over 20 Years
-
1/F Run Run Shaw Hall
PL 4.2 Ole Doering
15:15
Ethics of Human Genetics in Society: the Challenge of Interaction and Ethical Governance
PL 4.3 Brad Therell
The World of Newborn Screening
15:15
Coffee Break
G/F Exhibition Hall
Symposium 10: Assisted Reproductive Technology
Chair: Clement Chan, Heston Kwong
S10.1 William Yeung
Preimplantation Genetic Diagnosis – an overview
S10.2 Yan-Wen Xu
1/F Run Run Shaw Hall
Preimplantation Genetic Diagnosis in China
S 10.3 Lee Schulman
Prenatal Diagnosis in Pregnancies evaluated by Preimplantation Genetic Diagnosis and Screening
S10.4 Heston Kwong
Regulation of Reproductive Technology in Hong Kong
Symposium 11: Diagnostics and Screening
Chair: Kin-Man Lui, Maureen Cleary
S11.1 Jin-Sung Lee
15:45
-
Molecular Characterization of the Disease Genes in Patients with Cornelia de Lange Syndrome
S11.2 Xue-Fan Gu
G/F Pao Yue Kong Auditorium
17:30
Current Situation of Newborn Screening in China
S11.3 Jian-Hui Jiang
Neonatal Screening and High Risk Screening for Inherited Inborn Errors of Metabolism in Guangzhou
S11.4 Yan-Ling Yang
The Diagnosis and Treatment of Chinese Patients with Organic Acidemias
Symposium 12: March of Dimes Symposium on Birth Defects in the Asia Pacific Region
Chair: Stephen Lam/ Christopher Howson
S12.1 Christopher Howson
Summary of the 2006 March of Dimes Global Report: Findings and Recommendations and 2010 WHO World
G/F Lim Por Yen Lecture Theatre
Health Assembly Initiative
S12.2 Stephen Lam
Overview of Current Status of Care and Prevention of Birth Defects in the Region
S12.3 Country Reports:
S12.3.1 Ishwar Verma
India
S12.3.2 Meow-Keong Thong
Malaysia
S12.3.3 Carmencita Padilla
Philippine Birth Defects Surveillance Project
S12.3.4 Pornswan Wasant
Thailand
Genzyme Workshop on Lysosomal Storage Disorders (LSO)
Chair: Karen Huen
W 4.1 David Sillence
Peri-Transplant Use of ERT in Lysosomal Disorders
G/F Pao Yue Kong Auditorium
W 4.2 Paul Hwu
17:30
19:00
Changing the natural history of a disease: Pompe Disease Model and Newborn Screening
W 4.3 Yung Chyung
Early Initiation of Enzyme Replacement Therapy in Mucopolysaccharidosis Type I and II
BioRad Workshop:
W 5.1 Stephen Okino
Quantitative Assessment of Chromatin Structure: Analysis of Epigenetically Regulated Gene Promoters
G/F Lim Por Yen Lecture Theatre
W 5.2 Yan Wang
Quantitative Assessment of Chromatin Structure: New Insights into Epigenetic Regulation
19:00
–
21:00
Conference Banquet
1/F Run Run Shaw Hall
3rd December 2010
Time
(Friday)
Venue
7:30
-
Registration
G/F Exhibition Hall
18:00
Plenary Session 5
Chair: Ping-Yan Lam, Nelson Tang
8:00
-
PL 5.1 Srikant Sarangi
Inside the Blackbox of Genetic Counseling Communication
1/F Run Run Shaw Hall
9:45
PL 5.2 Hilary Burton
Genetics and Mainstream Medicine: Service development and integration
PL 5.3 Yuan-Tsong Chen
9:45
Coffee Break
G/F Exhibition Hall
Symposium 13: Genetic Counseling
Chair: Arnold Christianson, David Chan
S13.1 Meow-Keong Thong
Genetic Counseling in a Multi- ethnic Asian Population: Pitfalls and Challenges
S13.2 Arnold Christianson
Medical Genetic Counseling in Primary Health Care – A South Africa Experience
10:15
12:00
1/F Run Run Shaw Hall
S13.3 Wei Li
Online Genetic Counselling for Albinism in China
S13.4 Claire Penn
Intercultural Genetic Counselling: Factors Influencing our Services
Symposium 14: Public Health Genomics
Chair: Chao-Ming Lin, Edgar Hau
S14.1 Kaori Muto
Regulatory Policy Options towards Direct-to-consumer Genetic Testing in Several Countries
S14.2 Suli Sui
G/F Pao Yue Kong Auditorium
Social and Ethical Issues in Application of Genetic Testing in China
S14.3 Lock-Hock Ngu
Inborn Errors of Metabolism in Malaysia: Challenges and Opportunities
S14.4 Irma Nippert
Health Needs Assessment as a Pre-requisite for Evidence-based Service Development in Developing Countries
Symposium 15: Pharmacogenomics, Personalized Medicine and New Technology
Chair: Brian Tomlinson, Ching-Wan Lam
S15.1 Ching-Wan Lam
Genetic Testing and Personalized Medicine
S15.2 Vivian Lee
G/F Lim Por Yen Lecture Theatre
Personalized Medicine in Anti-platelet Therapy: What is the Clinical Impact?
S15.3 Sang-Seop Lee
Genetic and Epigenetic Variation Affecting Cytochrome P450 Expression
S15.4 Shea-Ping Yip
High Resolution Melting (HRM) Analysis – An Overview and Update
Free Paper Session 4: Epigenetics, Genetics in Population, Complex Disorders and Treatment
Chair: Chris Lau, Tony Tong
FP4.1 L Fu
Epigenetic Alteration of Organic Cation Transporter Gene SLC22A3 Confers Susceptibility to Esophageal
Cancer in the High-risk Northern Chinese
FP4.2 Brian Chung
Genome-wide Epigenetic Profiling Shows Evidence of Crosstalk Between Histone Modification and DNA
Methylation in Patients with Intellectural Disability Syndrome due to JARID1c Mutations
FP4.3 Nassiri Mohammadreza
Population Genetic Analysis of Iranian Gilak Ethnic Data Using 8 STR Markers
FP4.4 Xue-Mei Wang
No Association Between the Tumor Necrosis Factor Alpha (TNF-alpha) and Obsessive-compulsive Disorder in
Chinese Han Population
2/F Function Room
FP4.5 Betty But
Enzyme Replacement Therapy for Mucopolysaccharidosis VI (Maroteaux-Lamy) Syndrome: Experience in
Hong Kong
12:00
-
Industrial Lunch Symposium (Illumina Co. Ltd)
Alex Helm
13:00
Illumina’s GWAS Roadmap: Next-generation Genotyping Studies in the post 1,000 Genomes Era
13:00
Poster Sessions
1/F Run Run Shaw Hall
1/F Foyer
Plenary Session 6
Chair: Chok-Wan Chan, Jin-Sung Lee
PL 6.1 Kwok-Yung Yuen
13:30
Novel Mechanism for Antiviral Treatment of Influenza
-
1/F Run Run Shaw Hall
PL 6.2 Qi Zhou
15:15
Pluripotent Stem Cells and the Potential Application in Regenerative Medicine
PL 6.3 Yoichi Matsubara
Towards Genomic Medicine: Challenges and Opportunities
15:15
Coffee Break
G/F Exhibition Hall
Symposium 16: Ethical, Legal and Social Issues
Chair: Edwin Hui, Suli-Sui
S16.1 Zifalil Alwi
Ethical Issues in Medical Genetics in the Muslim World
S16.2 Kaori Muto
15:45
-
1/F Run Run Shaw Hall
Ethical, Legal and Social Issues on Genetic and Genomic Research
S16.3 Pang-Chui Shaw
17:30
Teaching Bioethics in a Science Curriculum - A Personal Account
S16.4 Thu-Nhanh Nguyen
Metabolic Disorder and Hereditary Diseases in Vietnamese Children (Ethical, Legal and Social Issues)
Symposium 17: Treatment of Diseases
G/F Pao Yue Kong Auditorium
Chair: Poh-San Lai, Joannie Hui
S17.1 Zhang Cheng
Experimental and Clinical Research on DMD Therapy with Bone Marrow Stem Cell Transplantation. (A DMD boy with
bone marrow transplantation and 6 years follow up.)
S17.2 Poh-San Lai
Genetic Treatments for Duchenne Muscular Dystrophy
S17.3 Andy Chiu
The Art of Reprogramming Somatic Cells into Embryonic-like Stem Cells and its Potential Application
S17.4 Thao Phuong Bui
Outcome of Female Hormone and Growth Hormone Treatment in Turner Syndrome
Symposium 18: Genetic Services
Chair: Hing-Wing Liu, Bao-Quan Pang
S18.1 Joerg Schmidtke
To Test or Not to Test: The Eurogentest Clinical Utility Gene Cards
S18.2 Pornswan Wasant
Provision of Comprehensive Clinical Genetic Service in Thailand – Twenty Three Year Experience
G/F Lim Por Yen Lecture Theatre
S18.3 Arnold Christianson
Establishing Primary Health Care Services for the Care & Prevention of Birth Defects in Middle- & Low-income Nations
S18.4 Ulf Kristofferson
How to Build Sustainable Structures for Clinical Genetic Services – Experiences from EUROGENTEST
Free Paper Session 5: Genome Variation, Cancer Genomics, Pharmacogenomics and Screening
Chair: Vivian Lee, Albert Lam
FP5.1 Stepanov VA
Eurasian Genetic Landscape: Gene Geography in the Mirror of Genome-wide Variability
FP5.2 Ka-Pou Iong
Newborn Screening in Fragile X Syndrome: A Pilot Study
FP5.3 Ren-Sheng Lai
Practical Application of Using Predictive Biomarkers to Select Patient with Metastatic Colorectal Cancer for
Treatment with Cetuximab
2/F Function Room
FP5.4 Yu-Feng Wang
No Association of AhR554A/G and ARNT 189G/C with Endometriosis in Women of the Southern Han
FP5.5 R. Ankathil
Contribution of BCR-ABL Kinase Domain Mutations to Imatinib Mesylate Resistance in Ph Chromosome
Positive Malaysian Chronic Myeloid Leukemia Patients
17:30
18:00
Closing Ceremony
1/F Run Run Shaw Hall
4th December 2010
Time
8:00
13:00
Visit to Hong Kong Science and Technology Park
Visit to Beijing Genome Institute, Hong Kong
(Saturday)