Panel on Interdisciplinary Science (by way of a few examples) Like yesterday’s, today’s panel is also about interdisciplinary science. Edoard Brezan and the members of his panel ran the event with elegance and thoroughness. They made a number of broad and fascinating statements on interdisciplinary science, and addressed various technical and philosophical questions raised by the audience. The dominant theme was the interaction between biology, on the one hand, and physics, mathematics and computer science, on the other. We did not mention the word engineering and technology explicitly yesterday, presumably in part because of the tacit assumption that these areas are subsumed by physics, and in part for a different reason that I will mention momentarily. We particularly focused on the question: what have the disciplines of physics, mathematics and computer science done for biology, and how best to continue on this path. Incidentally, it was deemed that it is too early to ask the inverse question of what biology has done for the other branches of science (though one can say that it has reinforced the view of emergence in science). Today’s panel will build on its predecessor, though with some differences, as I shall explain. The most important characteristic of science is that it is built on external evidence, which can be replicated by independent agents, rather than rely on revealed texts or one’s subjective feelings. There are parts of science which are driven by perennial questions of the type: What is life? What is the ultimate constituent of matter? How was our universe created? Is there life elsewhere in the universe? Efforts emanating from such questions are the basis of fundamental sciences such as biology, physics, cosmology and astrobiology. These subjects march inexorably, if slowly, towards their chosen goals; they independently develop most of the tools needed for their inquiry; they create their own traditions, often seek elegance, generality and connectedness, even though, perhaps paradoxically, the path is often paved with speculative and tentative steps---as well as many missteps. The process is not particularly efficient. The situation is different from the pursuit of transient objectives (though by no means trivial), such as putting man on the moon, in which a team of scientists and engineers works in a multidisciplinary framework, efficiently adopting available knowledge by and large, and creatively filling the gaps with expedient but reliable empiricism. This realization may have been another reason why we stayed away yesterday from issues of technology and engineering. The general feeling was that we are concerned here with creating new knowledge, or “making discoveries”. One other comment may be useful. Scientific disciplines are organized both vertically and horizontally. For example, in physics, people organize themselves around certain scales in a vertical hierarchy: e.g., scales of human experience, atomic and molecular scales, the scale of quarks, and the scale of strings, etc; in biology, the organization would be around scales of molecules and proteins, cells, organs, etc. There are complementary views on how one level on these vertical scales is related to the next: the reductionist view and the emergent view. I will not get into that discussion, although we might return to it later, but it appears, in general, to be easier to make transitions across disciplines at the same horizontal level. For example, it is easier for a condensed matter physicist to enter molecular and cellular biology than it is for a string theorist. For setting the stage today and building continuity, allow me to summarize some salient points that came up yesterday. Clearly all statements have exceptions, so they are simply guidelines. 1. One should have a solid grounding in one discipline before one can hope to be particularly successful in another. A poor physicist cannot bring a new perspective on biology. His lack of grounding in physics need not prevent him from becoming a successful biologist, but, then, he will likely not be able to provide an added value. Thus, while broad education is attractive for successful interdisciplinary work, depth in one or two areas is essential. 2. The transition of physicists into biology has been hugely successful at the level of tools, less so at the fundamental level of discoveries. Some circumspection in making the transition is desirable. We know that asking the right question is most often more important than providing the solution. One merit of the making the transition when one has a perspective of one’s own is that one has a chance to ask an unusual question. 3. The tools that work successfully in one area may not work even in a seemingly similar area: for example, the renormalization group method, which was enormously successful in determining scaling exponents in critical phenomena, has had no success in turbulence. Quantum field theory has also not yielded much. So both humility and patience are needed in interdisciplinary work. It is not always the case that science progresses along boundaries. 4. The strength of physics training lies in its emphasis on problemsolving, drilled into students by requiring them to look at the world at several different levels, from continuum to quarks, nearly paralleling the history of the evolution of the subject itself, instead of jumping to the top of the heap immediately. Biology does not do this. 5. Scientific collaboration between two people who both know their fields and methods is the most successful way to produce good interdisciplinary work. There is, however, a dominant theme and a dominant partner. 6. Centres such as ICTS can be more successful at promoting interdisciplinary work than traditional departments, which, for good reasons, are organized along disciplinary lines. Our panel can no doubt shed further light on these and related issues. But the panel members are not sure that they can add something entirely different. In fact, all panels on interdisciplinary science touch upon similar issues. Therefore, they prefer to speak on one or two specific problems in which interdisciplinarity has played an important role in their own research. However, they agreed that I could make these general statements---and take all the flak for being vague and grandiose. Each of our panel members will speak for between 10 and 15 min on something concrete. Please hold off questions to the end until all panelists have spoken. I don’t like the arrangement myself but it will ensure that we have time for questions on the totality of issues. They will then discuss all questions you may wish to pose for them---whether on their own presentations or on general aspects of interdisciplinary science. It would be nice if you could abstract how interdisciplinarity has played a role in the work to be presented, and ask questions in that slightly more general way. The panelists today are Sriram Ramaswamy (from IISc, who is a condensed matter theorist), Subir Sachdev (from Harvard, a condensed matter theorist), and Eitan Tadmor (from the University of Maryland, an applied and computational mathematician) and Mukund Thattai (NCBS, biologist). I am myself primarily a fluid dynamicist.