Issue #5, July 2008 Editor, Ron Bose, M.D., Ph.D. Assistant Professor, Department of Medicine Washington University School of Medicine, St. Louis, MO Table of Contents -Nominations Sought for 2009 New Drugs on the Horizon -New Funding Opportunities -Upcoming Events -CICR Membership Editor’s Note --Ron Bose, M.D., Ph.D. This newsletter is published quarterly and contributions from any AACR member are welcome. Comments, submissions, or questions should be directed to me at rbose@im.wustl.edu and to Eileen K. Dougherty, our AACR Program Coordinator, at eileen.dougherty@aacr.org. NOMINATIONS SOUGHT FOR 2009 NEW DRUGS ON THE HORIZON Drs. Steve Davidsen (Abbott Laboratories) and Emma Lees (Schering-Plough Biopharma) have again agreed to serve as Co-Chairs for the Drugs on the Horizon Special Session at the AACR Annual Meeting 2009. If your organization has a nomination for a development compound/target for the 2009 symposium, please contact Dr. Davidsen at steve.k.davidsen@abbott.com. As a reminder, the symposium is geared toward the first disclosure of the chemistry and biology of new drug candidates which are either nearing clinical development or have entered clinical trials. All participants must agree to the disclosure of the chemical structure of the development compound. We look forward to your nominations. AACR HENRY SHEPARD BLADDER CANCER RESEARCH GRANTS The 2008 AACR Henry Shepard Bladder Cancer Research Grants represent a joint effort of the Henry H. Shepard Trust and the American Association for Cancer Research. These two-year Grants will provide up to $250,000 in total support for innovative cancer research projects designed to accelerate the discovery, development, and application of new agents to treat bladder cancer and/or for pre-clinical research with direct therapeutic intent. There are four grants available, and the application deadline is on Friday, July 25, 2008 at 12:00 noon, U.S. Eastern Time. Please submit your applications online via proposalCENTRAL. For more information on program guidelines and application instructions, please click here. UPCOMING EVENTS Chemical Insights into Biological Processes August 15-16, 2008, Hood College, Frederick, Maryland In conjunction with the launch of the Center for Cancer Research's Molecular Discovery Program and the new Chemical Biology Laboratory, the Center for Cancer Research is hosting a Symposium, entitled "Chemical Insights into Biological Processes." This Symposium will be a two-day event focused on emerging and state-of-the-art chemistry approaches to difficult biological problems, with special emphasis on cancer and HIV/AIDS. Registration is free, however pre-registration is required. The deadline for abstract submissions is Tuesday, July 1, and the registration deadline is Friday, August 1. For more information, please visit the Symposium website. Chemical and Biological Aspects of Inflammation and Cancer October 14-17, 2008, Ko Olina, Oahu, Hawaii Molecular Targets and Cancer Therapeutics October 21-24, 2008, Geneva Palexpo, Geneva, Switzerland This symposium, hosted by EORTC, NCI and AACR, will bring together academics and scientists and representatives from the pharmaceutical industry to discuss innovation in drug development, target selection and the impact of new discoveries in molecular and cell biology. Understanding the pathways and mechanisms which cause cancer and regulate the biological behavior of tumor cells has lead to the development of numerous new agents and innovative targets for clinical trials. This conference has been organized to reflect the many recent advances in the early development of promising new compounds, which are in different levels of preclinical and clinical development. It will bring together delegates from all over the world igniting a huge exchange of information and promoting and developing global partnerships in translational research. The conference has been developed to ensure the maximum amount of interaction and discussion. For more information, please visit the 2008 Symposium website. Targeting the PI3-Kinase Pathway in Cancer November 11-14, 2008, Cambridge, Massachusetts Tumor Immunology: New Perspectives December 2-5, 2008, Miami, Florida Infection and Cancer: Biology, Therapeutics, and Prevention December 5-7, 2008, Hong Kong SAR, China Chemistry in Cancer Research: A Vital Partnership in Cancer Drug Discovery and Development A joint meeting between the AACR and the American Chemical Society February 8-11, 2009, Westin Canal Place, New Orleans, Louisiana This conference was first presented in 2007 to address the importance of chemistry in cancer research. It was highly successful and featured lectures several key chemically oriented areas of cancer research. The next conference will continue to address the role of chemistry in cancer research, but will focus most specifically on cancer drug development. Topics will include target identification and validation, chemical libraries, chemoinformatics, drug targeting, and drug delivery, among others. The inclusion of short presentations from abstracts submitted by younger investigators is an essential part of the program, in order to energize younger chemical investigators and inform them of the many opportunities to apply the power of chemistry to important problems in cancer research. Please check the CICR website for further details as they become available. CICR MEMBERSHIP The AACR will automatically renew your membership to the CICR Working Group unless you inform the AACR that you no longer wish to be a member. Please encourage your colleagues to join! Questions about CICR membership may be sent to cicr@aacr.org. Please visit the CICR website. To be removed from this list please e-mail Program Coordinator Eileen K. Dougherty at eileen.dougherty@aacr.org. Click here to update your e-mail address or contact information. Click here if you forgot your account ID and password for eServices.