Torsades de pointes tachycardia induced by common cold compound medication containing chlorpheniramine.
Nia AM, Fuhr U, Gassanov N, Erdmann E, Er F.
Eur J Clin Pharmacol. 2010 Nov;66(11):1173-5. Epub 2010 Jul 31. No abstract available.
PMID: 20676621 [PubMed - indexed for MEDLINE]
[Elderly patient with acquired long QT syndrome secondary to Levetiracetam.]
Rojano Martín B, Maroto Rubio M, Bilbao Ornazabal N, Martín-Sánchez FJ.
Neurologia. 2010 Nov 26. [Epub ahead of print] Spanish. No abstract available.
PMID: 21163209 [PubMed - as supplied by publisher] Free Article
Acquired long QT interval in a recurrent septic female patient with polymorphic ventricular tachycardia due to primary acute adrenal insufficiency.
Soutodeh R, Götz J, Tebbe U, Cuneo A.
Clin Res Cardiol. 2010 Dec 14. [Epub ahead of print] No abstract available.
PMID: 21161542 [PubMed - as supplied by publisher]
Acquired Long QT from Stress Cardiomyopathy is Associated with Ventricular Arrhythmias and Torsades de
Pointes.
Madias C, Fitzgibbons TP, Alsheikh-Ali AA, Bouchard JL, Kalsmith B, Garlitski AC, Tighe DA, Estes NA 3rd,
Aurigemma GP, Link MS.
Heart Rhythm. 2010 Dec 9. [Epub ahead of print]
PMID: 21146632 [PubMed - as supplied by publisher]
Oxidative inactivation of the lipid phosphatase 'phosphatase and tensin homolog on chromosome ten' (PTEN) as a novel mechanism of acquired long QT syndrome.
Wan X, Dennis AT, Obejero-Paz C, Overholt JL, Heredia-Moya J, Kirk KL, Ficker E.
J Biol Chem. 2010 Nov 20. [Epub ahead of print]
PMID: 21097842 [PubMed - as supplied by publisher] Free Article
Drug-induced long QT syndrome.
Kannankeril P, Roden DM, Darbar D.
Pharmacol Rev. 2010 Dec;62(4):760-81.
PMID: 21079043 [PubMed - in process]
Genesis of Phase-3 Early Afterdepolarizations and Triggered Activity in Acquired Long QT Syndrome.
Maruyama M, Lin SF, Xie Y, Chua SK, Joung B, Han S, Shinohara T, Shen MJ, Qu Z, Weiss JN, Chen PS.
Circ Arrhythm Electrophysiol. 2010 Nov 15. [Epub ahead of print]
PMID: 21078812 [PubMed - as supplied by publisher]
Fragmented QRS is associated with torsades de pointes in patients with acquired long QT syndrome.
Haraoka K, Morita H, Saito Y, Toh N, Miyoshi T, Nishii N, Nagase S, Nakamura K, Kohno K, Kusano KF,
Kawaguchi K, Ohe T, Ito H.
Heart Rhythm. 2010 Dec;7(12):1808-14. Epub 2010 Sep 15.
PMID: 20837161 [PubMed - in process]
Calcium oscillations and T-wave lability precede ventricular arrhythmias in acquired long QT type 2.
Němec J, Kim JJ, Gabris B, Salama G.
Heart Rhythm. 2010 Nov;7(11):1686-94. Epub 2010 Jul 3.
PMID: 20599524 [PubMed - in process]
Supporting Families. Saving Lives.
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Cardiac arrhythmia and thyroid dysfunction: a novel genetic link.
Purtell K, Roepke TK, Abbott GW.
Int J Biochem Cell Biol. 2010 Nov;42(11):1767-70. Epub 2010 Aug 3.
PMID: 20688187 [PubMed - in process]
Clinical and mechanistic issues in early repolarization of normal variants and lethal arrhythmia syndromes.
Benito B, Guasch E, Rivard L, Nattel S.
J Am Coll Cardiol. 2010 Oct 5;56(15):1177-86. Review.
PMID: 20883924 [PubMed - indexed for MEDLINE]
The Electro-Mechanical window: a risk marker for Torsade de Pointes in a canine model of drug induced arrhythmias. van der Linde HJ, Van Deuren B, Somers Y, Loenders B, Towart R, Gallacher DJ.
Br J Pharmacol. 2010 Dec;161(7):1444-54. doi: 10.1111/j.1476-5381.2010.00934.x.
PMID: 21054337 [PubMed - in process]
Early afterdepolarizations and cardiac arrhythmias.
Weiss JN, Garfinkel A, Karagueuzian HS, Chen PS, Qu Z.
Heart Rhythm. 2010 Dec;7(12):1891-9. Epub 2010 Sep 22.
PMID: 20868774 [PubMed - in process]
Imaging phenotype vs genotype in nonhypertrophic heritable cardiomyopathies: dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy.
Raman SV, Basso C, Tandri H, Taylor MR.
Circ Cardiovasc Imaging. 2010 Nov 1;3(6):753-65. Review. No abstract available.
PMID: 21081743 [PubMed - indexed for MEDLINE]
Epsilon waves during ventricular tachycardia in a case of arrhythmogenic right ventricular dysplasia.
Menon SM, Healey JS, Morillo CA.
Circulation. 2010 Oct 26;122(17):1752-5. No abstract available.
PMID: 20975011 [PubMed - indexed for MEDLINE]
'Stack of coins' indicative of arrhythmogenic right-ventricular dysplasia.
Ramcharitar S, Foley PW, Manghat NE.
Heart. 2010 Nov;96(21):1743. Epub 2010 Aug 23. No abstract available.
PMID: 20736194 [PubMed - indexed for MEDLINE]
Risk of sudden death in asymptomatic Brugada syndrome: not as high as we thought and not as low as we wished…but the contrary.
Viskin S, Rosso R.
J Am Coll Cardiol. 2010 Nov 2;56(19):1585-8. No abstract available.
PMID: 21029875 [PubMed - indexed for MEDLINE]
The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization.
Wilde AA, Postema PG, Di Diego JM, Viskin S, Morita H, Fish JM, Antzelevitch C.
J Mol Cell Cardiol. 2010 Oct;49(4):543-53. Epub 2010 Jul 24.
PMID: 20659475 [PubMed - indexed for MEDLINE]
Role of family history of sudden death in risk stratification and prevention of sudden death with implantable defibrillators in hypertrophic cardiomyopathy.
Bos JM, Maron BJ, Ackerman MJ, Haas TS, Sorajja P, Nishimura RA, Gersh BJ, Ommen SR.
Am J Cardiol. 2010 Nov 15;106(10):1481-6.
PMID: 21059440 [PubMed - indexed for MEDLINE]
SADS Quarterly Research Literature Review 2010 – Q4. Page 2

Lead extraction in pediatric and congenital heart disease patients.
Cecchin F, Atallah J, Walsh EP, Triedman JK, Alexander ME, Berul CI.
Circ Arrhythm Electrophysiol. 2010 Oct 1;3(5):437-44. Epub 2010 Aug 20.
PMID: 20729392 [PubMed - indexed for MEDLINE]
Prevalence and persistence of depression in patients with implantable cardioverter defibrillator: a 2-year longitudinal study.
Suzuki T, Shiga T, Kuwahara K, Kobayashi S, Suzuki S, Nishimura K, Suzuki A, Ejima K, Manaka T, Shoda M,
Ishigooka J, Kasanuki H, Hagiwara N.
Pacing Clin Electrophysiol. 2010 Dec;33(12):1455-61. doi: 10.1111/j.1540-8159.2010.02887.x. Epub 2010 Oct 14.
PMID: 20946285 [PubMed - in process]
Implantable cardioverter defibrillator therapy for congenital long QT syndrome: a single-center experience.
Horner JM, Kinoshita M, Webster TL, Haglund CM, Friedman PA, Ackerman MJ.
Heart Rhythm. 2010 Nov;7(11):1616-22. Epub 2010 Sep 17.
PMID: 20816872 [PubMed - in process]
Opioid maintenance patients with QTc prolongation: congenital long QT syndrome mutation may be a contributing risk factor.
Anchersen K, Hansteen V, Gossop M, Clausen T, Waal H.
Drug Alcohol Depend. 2010 Dec 1;112(3):216-9. Epub 2010 Aug 10.
PMID: 20702049 [PubMed - in process]
Long QT syndrome with compound mutations is associated with a more severe phenotype: a Japanese multicenter study.
Itoh H, Shimizu W, Hayashi K, Yamagata K, Sakaguchi T, Ohno S, Makiyama T, Akao M, Ai T, Noda T, Miyazaki A,
Miyamoto Y, Yamagishi M, Kamakura S, Horie M.
Heart Rhythm. 2010 Oct;7(10):1411-8. Epub 2010 Jun 9.
PMID: 20541041 [PubMed - in process]
Fetal atrioventricular block and postpartum augmentative QT prolongation in a patient with long-QT syndrome with
KCNQ1 mutation.
Furushima H, Chinushi M, Sato A, Aizawa Y, Kikuchi A, Takakuwa K, Tanaka K.
J Cardiovasc Electrophysiol. 2010 Oct;21(10):1170-3. doi: 10.1111/j.1540-8167.2010.01758.x.
PMID: 20487114 [PubMed - in process]
Repolarization dynamics during exercise discriminate between LQT1 and LQT2 genotypes.
Sy RW, Chattha IS, Klein GJ, Gula LJ, Skanes AC, Yee R, Bennett MT, Krahn AD.
J Cardiovasc Electrophysiol. 2010 Nov;21(11):1242-6. doi: 10.1111/j.1540-8167.2010.01788.x.
PMID: 20455992 [PubMed - in process]
The prevalence and diagnostic/prognostic utility of sinus arrhythmia in the evaluation of congenital long QT syndrome.
Johnson JN, Ackerman MJ.
Heart Rhythm. 2010 Dec;7(12):1785-9. Epub 2010 Jul 29.
PMID: 20673812 [PubMed - in process]
Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2.
Cordeiro JM, Perez GJ, Schmitt N, Pfeiffer R, Nesterenko VV, Burashnikov E, Veltmann C, Borggrefe M, Wolpert
C, Schimpf R, Antzelevitch C.
Can J Physiol Pharmacol. 2010 Dec;88(12):1181-90.
PMID: 21164565 [PubMed - in process]
Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
Lian J, Huang N, Zhou J, Ge S, Huang X, Huo J, Liu L, Xu W, Zhang S, Yang X, Zhou J, Huang C.
Can J Cardiol. 2010 Oct;26(8):417-22.
PMID: 20931094 [PubMed - indexed for MEDLINE]
SADS Quarterly Research Literature Review 2010 – Q4. Page 3

Triggers for cardiac events in patients with type 2 long QT syndrome.
Darbar D.
Heart Rhythm. 2010 Dec;7(12):1806-7. Epub 2010 Sep 29. No abstract available.
PMID: 20887809 [PubMed - in process] Free PMC Article Free text
Heart rate-dependent variability of cardiac events in type 2 congenital long-QT syndrome.
Nagaoka I, Shimizu W, Mizusawa Y, Sakaguchi T, Itoh H, Ohno S, Makiyama T, Yamagata K, Makimoto H,
Miyamoto Y, Kamakura S, Horie M.
Europace. 2010 Nov;12(11):1623-9. Epub 2010 Sep 29.
PMID: 20880952 [PubMed - in process]
Prevalence and spectrum of large deletions or duplications in the major long QT syndrome-susceptibility genes and implications for long QT syndrome genetic testing.
Tester DJ, Benton AJ, Train L, Deal B, Baudhuin LM, Ackerman MJ.
Am J Cardiol. 2010 Oct 15;106(8):1124-8.
PMID: 20920651 [PubMed - indexed for MEDLINE]
LQTS gene LOVD database.
Zhang T, Moss A, Cong P, Pan M, Chang B, Zheng L, Fang Q, Zareba W, Robinson J, Lin C, Li Z, Wei J, Zeng Q;
Long QT International Registry Investigators; HVP-China Investigators, Qi M.
Hum Mutat. 2010 Nov;31(11):E1801-10.
PMID: 20809527 [PubMed - indexed for MEDLINE]
Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen.
Peal DS, Mills RW, Lynch SN, Mosley JM, Lim E, Ellinor PT, January CT, Peterson RT, Milan DJ.
Circulation. 2011 Jan 4;123(1):23-30. Epub 2010 Nov 15.
PMID: 21098441 [PubMed - in process]
A novel mechanism for LQT3 with 2:1 block: a pore-lining mutation in Nav1.5 significantly affects voltagedependence of activation.
Horne AJ, Eldstrom J, Sanatani S, Fedida D.
Heart Rhythm. 2010 Dec 27. [Epub ahead of print]
PMID: 21193062 [PubMed - as supplied by publisher]
Sex-differences in sodium/calcium exchange expression is a determinant of the arrhythmia phenotype in prepubertal rabbit hearts with Long QT type 2.
Chen G, Yang X, Kerchner LJ, Salama NR, Alber S, Shusterman V, London B, Salama G.
Heart Rhythm. 2010 Dec 27. [Epub ahead of print]
PMID: 21193060 [PubMed - as supplied by publisher]
[The long QT syndrome].
Garweg C, D'Orio V, Mélon P, Lancellotti P, Piérard LA.
Rev Med Liege. 2010 Nov;65(11):628-33. French.
PMID: 21189529 [PubMed - in process]
Risk for Life-Threatening Cardiac Events in Patients With Genotype-Confirmed Long-QT Syndrome and Normal-
Range Corrected QT Intervals.
Goldenberg I, Horr S, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati
EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Platonov PG, Priori SG, Qi M, Schwartz PJ, Shimizu W,
Towbin JA, Vincent GM, Wilde AA, Zhang L.
J Am Coll Cardiol. 2010 Dec 28;57(1):51-9.
PMID: 21185501 [PubMed - in process]
DNA Structural Variants as Genetic Risk Factors for the Long QT Syndrome.
Rich SS, Hall IM.
J Am Coll Cardiol. 2010 Dec 28;57(1):48-50. No abstract available.
PMID: 21185500 [PubMed - in process]
Screening for Copy Number Variation in Genes Associated With the Long QT Syndrome Clinical Relevance.
Barc J, Briec F, Schmitt S, Kyndt F, Le Cunff M, Baron E, Vieyres C, Sacher F, Redon R, Le Caignec C, Le Marec
H, Probst V, Schott JJ.
J Am Coll Cardiol. 2010 Dec 28;57(1):40-7.
PMID: 21185499 [PubMed - in process]
SADS Quarterly Research Literature Review 2010 – Q4. Page 4

Reciprocal Control of hERG Stability by Hsp70 and Hsc70 With Implication for Restoration of LQT2 Mutant
Stability.
Li P, Ninomiya H, Kurata Y, Kato M, Miake J, Yamamoto Y, Igawa O, Nakai A, Higaki K, Toyoda F, Wu J, Horie M,
Matsuura H, Yoshida A, Shirayoshi Y, Hiraoka M, Hisatome I.
Circ Res. 2010 Dec 23. [Epub ahead of print]
PMID: 21183741 [PubMed - as supplied by publisher]
Changes in Ventricular Repolarization Duration During Typical Daily Emotion in Patients With Long QT Syndrome.
Lane RD, Zareba W, Reis HT, Peterson DR, Moss AJ.
Psychosom Med. 2011 Jan;73(1):98-105. Epub 2010 Dec 23.
PMID: 21183717 [PubMed - in process]
Cost-Effectiveness of Genetic Testing in Family Members of Patients With Long-QT Syndrome.
Perez MV, Kumarasamy NA, Owens DK, Wang PJ, Hlatky MA.
Circ Cardiovasc Qual Outcomes. 2010 Dec 7. [Epub ahead of print]
PMID: 21139095 [PubMed - as supplied by publisher]
Comparison of QT peak and QT end interval responses to autonomic adaptation in asymptomatic LQT1 mutation carriers.
Haapalahti P, Viitasalo M, Perhonen M, Väänänen H, Mäkijärvi M, Swan H, Toivonen L.
Clin Physiol Funct Imaging. 2010 Dec 7. doi: 10.1111/j.1475-097X.2010.01002.x. [Epub ahead of print]
PMID: 21138517 [PubMed - as supplied by publisher]
Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits.
Bentzen BH, Bahrke S, Wu K, Larsen AP, Odening KE, Franke G, van S Gravesande KS, Biermann J, Peng X,
Koren G, Zehender M, Bode C, Grunnet M, Brunner M.
J Cardiovasc Pharmacol. 2010 Nov 26. [Epub ahead of print]
PMID: 21135701 [PubMed - as supplied by publisher]
Presentation and outcome of water-related events in children with long QT syndrome.
Albertella L, Crawford J, Skinner JR.
Arch Dis Child. 2010 Dec 3. [Epub ahead of print] No abstract available.
PMID: 21131640 [PubMed - as supplied by publisher]
Molecular screening of long-QT syndrome: risk is there or rare?
Aiba T, Shimizu W.
Heart Rhythm. 2010 Dec 2. [Epub ahead of print] No abstract available.
PMID: 21130900 [PubMed - as supplied by publisher]
Origin of the Swedish Long QT Syndrome Y111C/KCNQ1 founder mutation.
Winbo A, Diamant UB, Rydberg A, Persson J, Jensen SM, Stattin EL.
Heart Rhythm. 2010 Nov 30. [Epub ahead of print]
PMID: 21129503 [PubMed - as supplied by publisher]
Elevated serum gastrin levels in Jervell and Lange-Neilsen syndrome: a marker of severe KCNQ1 dysfunction?
Rice KS, Dickson G, Lane M, Crawford J, Chung SK, Rees MI, Shelling AN, Love DR, Skinner JR.
Heart Rhythm. 2010 Nov 30. [Epub ahead of print]
PMID: 21118729 [PubMed - as supplied by publisher]
Functional effects of a missense mutation in HERG associated with type 2 Long QT syndrome.
Amorós I, Jiménez-Jáimez J, Tercedor L, Barana A, Gómez R, de la Fuente MG, Dolz-Gaitón P, Alvarez M,
Martínez-Espín E, Lorente JA, Melgares R, Tamargo J, Delpón E, Caballero R.
Heart Rhythm. 2010 Nov 22. [Epub ahead of print]
PMID: 21109023 [PubMed - as supplied by publisher]
A Common SCN5A Polymorphism Modulates the Biophysical Defects of SCN5A Mutations.
Shinlapawittayatorn K, Du XX, Liu H, Ficker E, Kaufman ES, Deschênes I.
Heart Rhythm. 2010 Nov 22. [Epub ahead of print]
PMID: 21109022 [PubMed - as supplied by publisher]
SADS Quarterly Research Literature Review 2010 – Q4. Page 5

Gene mutations associated with atrioventricular block complicated by long QT syndrome.
Nishizaki M, Hiraoka M.
Circ J. 2010 Nov 25;74(12):2546-7. Epub 2010 Nov 13. No abstract available.
PMID: 21088333 [PubMed - in process] Free Article
Prospective, population-based long QT molecular autopsy study of post-mortem negative sudden death in 1-40 year olds.
Skinner JR, Crawford J, Smith W, Aitken A, Heaven D, Evans CA, Hayes I, Neas KR, Stables S, Koelmeyer T,
Denmark L, Vuletic J, Maxwell F, White K, Yang T, Roden DM, Leren TP, Shelling A, Love DR; Cardiac Inherited
Disease Group New Zealand.
Heart Rhythm. 2010 Nov 8. [Epub ahead of print]
PMID: 21070882 [PubMed - as supplied by publisher]
Multiple splicing defects caused by hERG splice site mutation 2592+1G>A associated with long QT syndrome.
Stump MR, Gong Q, Zhou Z.
Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H312-8. Epub 2010 Nov 5.
PMID: 21057041 [PubMed - in process]
Human cardiomyocytes with long-QT syndrome in dish.
Seifinejad A, Baharvand H.
Arch Iran Med. 2010 Nov;13(6):573-5. No abstract available.
PMID: 21039019 [PubMed - in process] Free Article
Inhibition of nonsense-mediated mRNA decay by antisense morpholino oligonucleotides restores functional expression of hERG nonsense and frameshift mutations in long-QT syndrome.
Gong Q, Stump MR, Zhou Z.
J Mol Cell Cardiol. 2010 Oct 28. [Epub ahead of print]
PMID: 21035456 [PubMed - as supplied by publisher]
Three Generations of Hereditary Long-QT Syndrome with Complete Penetrance Caused by the p.G316E KCNQ1
Mutation.
Viadero MT, Rubín E, Amigo T, González-Lamuño D.
Pediatr Cardiol. 2010 Oct 28. [Epub ahead of print]
PMID: 20981542 [PubMed - as supplied by publisher]
Torsades: adjacent and triggering electrocardiographic events.
Childers R.
J Electrocardiol. 2010 Nov-Dec;43(6):515-23. Epub 2010 Sep 15.
PMID: 20832817 [PubMed - in process]
Atrioventricular block-induced Torsades de Pointes with clinical and molecular backgrounds similar to congenital long QT syndrome.
Oka Y, Itoh H, Ding WG, Shimizu W, Makiyama T, Ohno S, Nishio Y, Sakaguchi T, Miyamoto A, Kawamura M,
Matsuura H, Horie M.
Circ J. 2010 Nov 25;74(12):2562-71. Epub 2010 Oct 21.
PMID: 20975234 [PubMed - in process] Free Article
Hereditary arrhythmia corner: learning from challenging patients. Family with suspect LQTS.
Goldenberg I, Huang DT, Balakrishnan S, Viskin S.
Ann Noninvasive Electrocardiol. 2010 Oct;15(4):384-6.
PMID: 20968108 [PubMed - in process]
Use of a Cardioselective Beta-Blocker for Pediatric Patients With Prolonged QT Syndrome.
Moltedo JM, Kim JJ, Friedman RA, Kertesz NJ, Cannon BC.
Pediatr Cardiol. 2010 Oct 20. [Epub ahead of print]
PMID: 20960185 [PubMed - as supplied by publisher]
Nicorandil normalizes prolonged repolarisation in the first transgenic rabbit model with Long-QT syndrome 1 both in vitro and in vivo.
Biermann J, Wu K, Odening KE, Asbach S, Koren G, Peng X, Zehender M, Bode C, Brunner M.
Eur J Pharmacol. 2011 Jan 10;650(1):309-16. Epub 2010 Oct 17.
PMID: 20959120 [PubMed - in process]
SADS Quarterly Research Literature Review 2010 – Q4. Page 6

Automated perioperative QT monitoring in a patient with long QT syndrome 2.
Anton D, Friederich P.
Br J Anaesth. 2010 Nov;105(5):701-2. No abstract available.
PMID: 20952434 [PubMed - indexed for MEDLINE]
A KCR1 variant implicated in susceptibility to the long QT syndrome.
Hayashi K, Fujino N, Ino H, Uchiyama K, Sakata K, Konno T, Masuta E, Funada A, Sakamoto Y, Tsubokawa T,
Hodatsu A, Yasuda T, Kanaya H, Kim MY, Kupershmidt S, Higashida H, Yamagishi M.
J Mol Cell Cardiol. 2010 Oct 13. [Epub ahead of print]
PMID: 20950623 [PubMed - as supplied by publisher]
Fragmented QRS: the new high-risk kid on the block in acquired long QT syndrome.
Moss AJ.
Heart Rhythm. 2010 Dec;7(12):1815-6. Epub 2010 Sep 22. No abstract available.
PMID: 20868773 [PubMed - in process]
Transmural differences in myocardial contraction in long-QT syndrome: mechanical consequences of ion channel dysfunction.
Haugaa KH, Amlie JP, Berge KE, Leren TP, Smiseth OA, Edvardsen T.
Circulation. 2010 Oct 5;122(14):1355-63. Epub 2010 Sep 20.
PMID: 20855658 [PubMed - indexed for MEDLINE]
Is long QT syndrome a disease of abnormal mechanical contraction?
Rosenbaum DS.
Circulation. 2010 Oct 5;122(14):1353-4. Epub 2010 Sep 20. No abstract available.
PMID: 20855657 [PubMed - indexed for MEDLINE]
Trigger-specific risk factors and response to therapy in long QT syndrome type 2.
Kim JA, Lopes CM, Moss AJ, McNitt S, Barsheshet A, Robinson JL, Zareba W, Ackerman MJ, Kaufman ES,
Towbin JA, Vincent M, Goldenberg I.
Heart Rhythm. 2010 Dec;7(12):1797-805. Epub 2010 Sep 17.
PMID: 20850565 [PubMed - in process]
Patient-specific induced pluripotent stem-cell models for long-QT syndrome.
Moretti A, Bellin M, Welling A, Jung CB, Lam JT, BottFlügel L, Dorn T, Goedel A, Höhnke C, Hofmann F, Seyfarth
M, Sinnecker D, Schömig A, Laugwitz KL.
N Engl J Med. 2010 Oct 7;363(15):1397-409.
PMID: 20660394 [PubMed - indexed for MEDLINE]
Repolarization variability and early afterdepolarizations in long QT syndrome type 2: is labile calcium the common denominator?
Antoons G, Thomsen MB.
Heart Rhythm. 2010 Nov;7(11):1695-6. Epub 2010 Aug 12. No abstract available.
PMID: 20624482 [PubMed - in process]
Long QT syndrome: a double hit hurts more.
Wilde AA.
Heart Rhythm. 2010 Oct;7(10):1419-20. Epub 2010 Jun 22. No abstract available.
PMID: 20601150 [PubMed - in process]
A novel SCN5A mutation associated with the linker between III and IV domains of Na(v)1.5 in a neonate with fatal long QT syndrome.
Yamamura K, Muneuchi J, Uike K, Ikeda K, Inoue H, Takahata Y, Shiokawa Y, Yoshikane Y, Makiyama T, Horie M,
Hara T.
Int J Cardiol. 2010 Nov 5;145(1):61-4. Epub 2009 May 6.
PMID: 19419784 [PubMed - in process]
SADS Quarterly Research Literature Review 2010 – Q4. Page 7

How the knowledge of genetic "makeup" and cellular data can affect the analysis of repolarization in surface electrocardiogram.
Shimizu W.
J Electrocardiol. 2010 Nov-Dec;43(6):583-7. Epub 2010 Jul 27.
PMID: 20667549 [PubMed - in process]
Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels.
Huang H, Priori SG, Napolitano C, O'Leary ME, Chahine M.
Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H288-99. Epub 2010 Nov 12.
PMID: 21076026 [PubMed - in process]
Ventricular remodeling and survival are more favorable for myocarditis than for idiopathic dilated cardiomyopathy in childhood: an outcomes study from the Pediatric Cardiomyopathy Registry.
Foerster SR, Canter CE, Cinar A, Sleeper LA, Webber SA, Pahl E, Kantor PF, Alvarez JA, Colan SD, Jefferies JL,
Lamour JM, Margossian R, Messere JE, Rusconi PG, Shaddy RE, Towbin JA, Wilkinson JD, Lipshultz SE.
Circ Heart Fail. 2010 Nov 1;3(6):689-97. Epub 2010 Sep 10.
PMID: 20833772 [PubMed - indexed for MEDLINE]
Voltage-Gated Sodium Channels: Mutations, Channelopathies and Targets.
Andavan GS, Lemmens-Gruber R.
Curr Med Chem. 2010 Dec 14. [Epub ahead of print]
PMID: 21143119 [PubMed - as supplied by publisher]
Arrhythmogenic hereditary syndromes: Brugada Syndrome, long QT syndrome, short QT syndrome and CPVT.
Schimpf R, Veltmann C, Wolpert C, Borggrefe M.
Minerva Cardioangiol. 2010 Dec;58(6):623-36.
PMID: 21135804 [PubMed - in process]
Fluconazole inhibits hERG K(+) channel by direct block and disruption of protein trafficking.
Han S, Zhang Y, Chen Q, Duan Y, Zheng T, Hu X, Zhang Z, Zhang L.
Eur J Pharmacol. 2011 Jan 10;650(1):138-44. Epub 2010 Oct 15.
PMID: 20951697 [PubMed - in process]
The stoichiometric relationship between KCNH-2 and KCNE-2 in I(Kr) channel formation.
Kim DG, Oh JH, Lee EH, Lee JH, Park HJ, Kim CY, Kwon MS, Yoon S.
Int J Cardiol. 2010 Nov 19;145(2):272-4. Epub 2009 Nov 13.
PMID: 19913309 [PubMed - in process]
Gender-related differences in ion-channel and transporter subunit expression in non-diseased human hearts.
Gaborit N, Varro A, Le Bouter S, Szuts V, Escande D, Nattel S, Demolombe S.
J Mol Cell Cardiol. 2010 Oct;49(4):639-46. Epub 2010 Jun 21.
PMID: 20600101 [PubMed - indexed for MEDLINE]
Cost and yield of adding EKG to history and physical in screening division I intercollegiate athletes: A five-year experience.
Malhotra R, West JJ, Dent J, Luna M, Kramer C, Mounsey JP, Battle R, Saliba E, Rose B, Mistry D, Macknight J,
Dimarco JP, Mahapatra S.
Heart Rhythm. 2010 Dec 16. [Epub ahead of print]
PMID: 21168529 [PubMed - as supplied by publisher]
Electrocardiogram screening of deaf children for long QT syndrome: are we following UK national guidelines?
Kang SL, Jackson C, Kelsall W.
J Laryngol Otol. 2010 Nov 17:1-3. [Epub ahead of print]
PMID: 21080985 [PubMed - as supplied by publisher]
SADS Quarterly Research Literature Review 2010 – Q4. Page 8

Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart
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Circulation. 2010 Nov 30;122(22):2335-48. No abstract available.
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Genetic predisposition to sudden cardiac death.
Crotti L.
Curr Opin Cardiol. 2010 Nov 19. [Epub ahead of print]
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Genetics of heart failure and sudden death.
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Heart Fail Clin. 2010 Oct;6(4):507-14, ix.
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Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: the experience of a tertiary referral center in The Netherlands. van der Werf C, Hofman N, Tan HL, van Dessel PF, Alders M, van der Wal AC, van Langen IM, Wilde AA.
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SADS Quarterly Research Literature Review 2010 – Q4. Page 9