药学院 2009 年 10 月共发表 SCI 论文 9 篇
1、
标题：Convenient and versatile synthesis of formyl-substituted benzoxaboroles
作者: Ye L (Ye, Long)1, Ding DZ (Ding, Dazhong)1, Feng YQ (Feng, Yiqing)1, Xie DS (Xie,
Dongsheng)1, Wu PH (Wu, Puhua)1, Guo H (Guo, Hui)1, Meng QQ (Meng, Qingqing)1,
Zhou HC (Zhou, Huchen)1
来源出版物: TETRAHEDRON
卷: 65
期: 42 页: 8738-8744 出版年: OCT 17 2009
被引频次: 0
参考文献: 19
摘要: Despite of the medicinal significance of benzoxaboroles, with the newly discovered clinical
compound AN2690 as an example, the synthetic method for rapid diversification of this
novel scaffold is lacking. To this end, a versatile and scalable synthesis of
formyl-substituted benzoxaboroles is described here. A key step is the mono-oxidation of
the two hydroxyls in compound 4 by taking advantage of the stable oxaborole ring in
non-coordinating solvents, which was devised based on the study of the intramolecular
coordination and exchange properties. (C) 2009 Elsevier Ltd. All rights reserved.
文献类型: Article
语言: English
KeyWords Plus: PINCER COMPLEXES; ANTIFUNGAL AGENT; ACID; DISCOVERY;
DESIGN
通讯作者地址: Zhou, HC (通讯作者), Shanghai Jiao Tong Univ, Sch Pharm, 800 Dong Chuan
Rd, Shanghai 200240, Peoples R China
地址:
1. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
电子邮件地址: hczhou@sjtu.edu.cn
基金资助致谢:
基金资助机构 授权号
National Natural Science Foundation of China 20702031
Shanghai Municipal Education Commission 07SG15
Science and Technology Commission of Shanghai Municipality 07pj14095
Ministry of Science and Technology of China 2009CB918404
Anacor Pharmaceuticals
出版商: PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE,
KIDLINGTON, OXFORD OX5 1GB, ENGLAND
学科类别: Chemistry, Organic
IDS 号: 504JE
ISSN: 0040-4020
DOI: 10.1016/j.tet.2009.08.026
2、
标题：SYNTHESIS OF PYRROL[2,3-d]PYRIMIDINE ANALOGUES: "PYRIDINE RING"
ANALOGUES OF PEMETREXED
作者: Xu Y (Xu, Yun)1, Yu MF (Yu, Mingfeng)1, Long Y (Long, Yan)1, Wu H (Wu, Han)1, Mao
ZM (Mao, Zhenmin)1
来源出版物: HETEROCYCLES
卷: 78
期: 9
页: 2353-2360
出版年: SEP 1
2009
被引频次: 0
参考文献: 19
摘要: Two analogues of pemetrexed with its phenyl ring replaced with pyridine ring as novel
anticancer agents were synthesized. Preliminary in vitro evaluation indicated that replacement of
the phenyl moiety of pemetrexed by the pyridine ring with the 6-5 bicyclic ring system showed
low cytotoxicity, that departs from the findings with antifolates bearing 6-6 bicyclic ring system.
文献类型: Article
语言: English
作者关键词: Pemetrexed; Pyridine Ring; Synthesis; Michael Addition; Net Reaction
KeyWords Plus: THYMIDYLATE SYNTHASE INHIBITORS; ANTICANCER AGENTS;
LY231514 MTA; ANTIFOLATE; PYRIDO<2,3-D>PYRIMIDINES; METHOTREXATE;
TNP-351; ACID
通讯作者地址: Xu, Y (通讯作者), Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240,
Peoples R China
地址:
1. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
电子邮件地址: zmmao@sjtu.edu.cn
基金资助致谢:
基金资助机构 授权号
Shanghai Science and Technology Committee 042319231
出版商: PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE,
KIDLINGTON, OXFORD OX5 1GB, ENGLAND
学科类别: Chemistry, Organic
IDS 号: 504TF
ISSN: 0385-5414
DOI: 10.3978/COM-09-11725
3、
标题：A New Chalcone Glycoside, a New Tetrahydrofuranoid Lignan, and Anti-oxidative
Constituents from the Stems and Leaves of Viburnum propinquum
作者: Wang XY (Wang, Xiao-Yu)1, Shi HM (Shi, Hai-Ming)1, Zhang L (Zhang, Li)2, Li XB (Li,
Xiao-Bo)1
来源出版物: PLANTA MEDICA
卷: 75
期: 11
页: 1262-1265
出版年: SEP
2009
被引频次: 0
参考文献: 14
摘要: A new chalcone glycoside (2) and a new tetrahydrofuranoid lignan (3), along with 12 known
compounds, were isolated from the stems and leaves of Viburnum propinquum Hemsl. The
structures of all isolated compounds were deduced using spectroscopic and chemical methods.
Antioxidative activities of most phenolic compounds were evaluated. Compounds 1
(3,4,2',4'-tetrahydroxy-trans-chalcone),
2
(3,4,2',4'-tetrahydroxy-trans-chalcone-2'-O-beta-D-glucoside),
12
(quercetin),
13
((+)-dihydroquercetin), and 14 (eriodictyol) showed antioxidative capacities in the DPPH and
hydroxyl free-radical assays, with IC50 values of 3.80-6.12 mu g/mL, and 9.24-11.87 mu g/mL,
respectively. Compounds 1, 2, 12, 13, and 14 also exhibited inhibitory activities against lipid
peroxidation in rat liver homogenate, with an inhibitory rate of 10.8-39.9% at 20 mu g/mL,
38.8-57.2% at 100 mu g/mL, and 44.2-72.4% at 200 mu g/mL, respectively.
文献类型: Article
语言: English
作者关键词: Viburnum propinquum; Caprifoliaceae; chalcone glycosides; tetrahydrofuranoid
lignan; antioxidative activity
通讯作者地址: Li, XB (通讯作者), Shanghai Jiao Tong Univ, Sch Pharm, 800 Dongchuan Rd,
Shanghai 200240, Peoples R China
地址:
1. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
2. Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai Mass Spectrometry Ctr, Shanghai
200032, Peoples R China
电子邮件地址: xbli@sjtu.edu.cn
出 版 商 : GEORG THIEME VERLAG KG, RUDIGERSTR 14, D-70469 STUTTGART,
GERMANY
学科类别: Plant Sciences; Chemistry, Medicinal; Pharmacology & Pharmacy
IDS 号: 501SE
ISSN: 0032-0943
DOI: 10.1055/s-0029-1185523
4、
标题：Serum Metabolite Profiling of Human Colorectal Cancer Using GC-TOFMS and
UPLC-QTOFMS
作者: Qiu YP (Qiu, Yunping)3, Cai GX (Cai, Guoxiang)1,2, Su MM (Su, Mingming)4, Chen TL
(Chen, Tianlu)5,6, Zheng XJ (Zheng, Xiaojiao)5,6, Xu Y (Xu, Ye)1,2, Ni Y (Ni, Yan)5,6, Zhao AH
(Zhao, Aihua)5,6, Xu LX (Xu, Lisa X.)5,6, Cai SJ (Cai, Sanjun)1,2, Jia W (Jia, Wei)3,4
来源出版物: JOURNAL OF PROTEOME RESEARCH
卷: 8
期: 10
页: 4844-4850
出版年: OCT 2009
被引频次: 0
参考文献: 38
摘要: Colorectal carcinogenesis involves the overexpression of many immediate-early response
genes associated with growth and inflammation, which significantly alters downstream protein
synthesis and small-molecule metabolite production. We have performed a serum metabolic
analysis to test the hypothesis that the distinct metabolite profiles of malignant tumors are
reflected in biofluids. In this study, we have analyzed the serum metabolites from 64 colorectal
cancer (CRC) patients and 65 healthy controls using gas chromatography time-of-flight mass
spectrometry (GC-TOFMS) and Acquity ultraperformance liquid chromatography-quadrupole
time-of-flight mass spectrometry (Acquity UPLC-QTOFMS). Orthogonal partial least-squares
discriminate analysis (OPLS-DA) models generated from GC-TOFMS and UPLC-QTOFMS
metabolic profile data showed robust discrimination from CRC patients and healthy controls. A
total of 33 differential metabolites were identified using these two analytical platforms, five of
which were detected in both instruments. These metabolites potentially reveal perturbation of
glycolysis, arginine and proline metabolism, fatty acid metabolism and oleamide metabolism,
associated with CRC morbidity. These results suggest that serum metabolic profiling has great
potential in detecting CRC and helping to understand its underlying mechanisms.
文献类型: Article
语言: English
作 者 关 键 词 : Colorectal cancer; metabonomics; gas chromatography time-of-flight mass
spectrometry; ultraperformance liquid chromatography quadrupole time-of-flight mass
spectrometry; serum
KeyWords Plus: DIABETES-MELLITUS PATIENTS; COLON-CANCER; IDENTIFYING
DIFFERENCES; CELL-PROLIFERATION; HEALTHY-VOLUNTEERS; L-ARGININE;
OLEAMIDE; GC/MS; CANNABINOIDS; EXPRESSION
通讯作者地址: Cai, SJ (通讯作者), Fudan Univ, Canc Hosp, Dept Colorectal Surg, 270 Dong Rd,
Shanghai 200032, Peoples R China
地址:
1. Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China
2. Fudan Univ, Shanghai Med Coll, Dept Colorectal Surg, Shanghai 200032, Peoples R China
3. Univ N Carolina Greensboro, Dept Nutr, Kannapolis, NC 28081 USA
4. David H Murdock Res Inst, Kannapolis, NC 28081 USA
5. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
6. Shanghai Jiao Tong Univ, Shanghai Ctr Syst Biomed, Shanghai 200240, Peoples R China
电子邮件地址: caisanjun@tom.com, w_jia@uncg.edu
基金资助致谢:
基金资助机构 授权号
National Basic Research Program of China 2007CB914700 ;2004CB518605
出版商: AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
学科类别: Biochemical Research Methods
IDS 号: 501BM
ISSN: 1535-3893
DOI: 10.1021/pr9004162
5、
标题：Characterization of Novel Quaternary Chitosan Derivative Nanoparticles Loaded with
Protein
作者: Wan A (Wan, Ajun)1, Sun Y (Sun, Yan)1, Li HL (Li, Huili)2
来源出版物: JOURNAL OF APPLIED POLYMER SCIENCE
卷: 114
期: 5
页:
2639-2647
出版年: DEC 5 2009
被引频次: 0
参考文献: 35
摘要: The objective of this work was to characterize a novel quaternary chitosan derivative
[O-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (O-HTCC)] nanoparticle system.
O-HTCC nanoparticles were prepared with a simple and mild ionic gelation method upon the
addition of a sodium tripolyphosphate solution to a low-molecular-weight O-HTCC solution.
Highly cationic chitosan nanoparticles were prepared. Bovine serum albumin (BSA), a model
protein drug, was incorporated into the nanoparticles. The physicochemical properties of the
nanoparticles were determined with transmission electron microscopy (TEM), scanning electron
microscopy (SEM), Fourier transform infrared analysis, differential scanning calorimetry, and
X-ray diffraction (XRD) patterns. The results showed that increasing the BSA concentration from
1.5 to 2.5 mg/mL promoted the BSA encapsulation efficiency from 57.3% to 87.5% and the
loading capacity from 70.2%, to 99.5%. Compared with the chitosan nanoparticles, the O-HTCC
nanoparticles had lower burst release. TEM revealed that the BSA-loaded O-HTCC nanoparticles
were smaller than the O-HTCC nanoparticles when the BSA concentration was 1.5 mg/mL; SEM
showed that the size of the BSA-loaded O-HTCC nanoparticles was mostly affected by the BSA
concentration, and the increase in size occurred with the concentration increasing. Thermograms
and XRD of the BSA-loaded nanoparticles suggested that polyelectrolyte-protein interactions
increased with the BSA concentration increasing and greater chain realignment in the BSA-loaded
nanoparticles. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 114: 2639-2647, 2009
文献类型: Article
语言: English
作者关键词: drug delivery systems; morphology; nanotechnology
KeyWords
Plus:
IN-VITRO
EVALUATION;
INTESTINAL-ABSORPTION;
DELIVERY-SYSTEMS;
DRUG;
CHLORIDE;
VACCINE;
MACROMOLECULES;
ENHANCEMENT; EPITHELIA; RELEASE
通讯作者地址: Wan, A (通讯作者), Shanghai Jiao Tong Univ, Sch Chem & Chem Technol,
Shanghai 200240, Peoples R China
地址:
1. Shanghai Jiao Tong Univ, Sch Chem & Chem Technol, Shanghai 200240, Peoples R China
2. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
电子邮件地址: wanajun@sjtu.edu.cn, lihl@sjtu.edu.cn
基金资助致谢:
基金资助机构 授权号
National Natural Science Foundation of China 20376045 ;20676079
Nanometer Technology Program of the Science and Technology Committee of Shanghai
0452nm037
出版商: JOHN WILEY & SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA
学科类别: Polymer Science
IDS 号: 502YO
ISSN: 0021-8995
DOI: 10.1002/app.28792
6、
标题：Traditional Chinese Medicine: Balancing the Gut Ecosystem
作者: Li HK (Li, Houkai)1, Zhou MM (Zhou, Mingmei)2, Zhao AH (Zhao, Aihua)1, Jia W (Jia,
Wei)1,2
来源出版物: PHYTOTHERAPY RESEARCH
卷: 23
期: 9
页: 1332-1335
出版
年: SEP 2009
被引频次: 0
参考文献: 30
摘要: Gut microflora has become a topic of interest in life sciences in the context of global
systems biology, in which human biological system is viewed as 'superorganisms' involving an
internal ecosystem of diverse microbiome. We conceive that multi-pathway modulations of the
human gut microbial system exerted by traditional Chinese medicines (TCMs) to restore the
balance of the gut ecology may account for a large portion of their effectiveness in host during
treatment. Such a concept is evidenced by series of studies which have revealed an interactive
relationship between gut microflora and TCM, involving the two important aspects: gut
microflora-dependent drug metabolism in TCM and gut microflora-targeted modulation of
physiological conditions, both of which highlight the significance of gut microflora involvement
in the future TCM investigation. Copyright (c) 2009 John Wiley & Sons, Ltd.
文献类型: Article
语言: English
作者关键词: traditional Chinese medicine; gut microflora; herbal medicine; drug metabolism
KeyWords Plus: INTESTINAL MICROFLORA; METABOLISM; RATS; METAGENOMICS;
MICROBIOTA; MOUSE
通讯作者地址: Jia, W (通讯作者), Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240,
Peoples R China
地址:
1. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
2. Shanghai Univ Tradit Chinese Med, Shanghai 201203, Peoples R China
电子邮件地址: weijia@sjtu.edu.cn
出版商: JOHN WILEY & SONS LTD, THE ATRIUM, SOUTHERN GATE, CHICHESTER
PO19 8SQ, W SUSSEX, ENGLAND
学科类别: Chemistry, Medicinal; Pharmacology & Pharmacy
IDS 号: 498NY
ISSN: 0951-418X
DOI: 10.1002/ptr.2590
7、
标 题 ： Hollow Sodium Tungsten Bronze (Na0.15WO3) Nanospheres: Preparation,
Characterization, and Their Adsorption Properties
作者: Hou J (Hou, Jing)1,2, Zuo GK (Zuo, Guanke)3, Shen GX (Shen, Guangxia)1, Guo H (Guo,
He)3, Liu H (Liu, Hui)3, Cheng P (Cheng, Ping)1, Zhang JY (Zhang, Jingyan)3, Guo SW (Guo,
Shouwu)1
来源出版物: NANOSCALE RESEARCH LETTERS
卷: 4
期: 10
页: 1241-1246
出版年: OCT 2009
被引频次: 0
参考文献: 27
作者: Hou J (Hou, Jing)1,2, Zuo GK (Zuo, Guanke)3, Shen GX (Shen, Guangxia)1, Guo H (Guo,
He)3, Liu H (Liu, Hui)3, Cheng P (Cheng, Ping)1, Zhang JY (Zhang, Jingyan)3, Guo SW (Guo,
Shouwu)1
来源出版物: NANOSCALE RESEARCH LETTERS
卷: 4
期: 10
页: 1241-1246
出版年: OCT 2009
被引频次: 0
参考文献: 27
引证关系图
摘要: We report herein a facile method for the preparation of sodium tungsten bronzes hollow
nanospheres using hydrogen gas bubbles as reactant for chemical reduction of tungstate to
tungsten and as template for the formation of hollow nanospheres at the same time. The chemical
composition and the crystalline state of the as-prepared hollow Na0.15WO3 nanospheres were
characterized complementarily, and the hollow structure formation mechanism was proposed. The
hollow Na0.15WO3 nanospheres showed large Brunauer-Emment-Teller specific area (33.8 m(2)
g(-1)), strong resistance to acids, and excellent ability to remove organic molecules such as dye
and proteins from aqueous solutions. These illustrate that the hollow nanospheres of Na0.15WO3
should be a useful adsorbent.
文献类型: Article
语言: English
作者关键词: Sodium tungsten bronze; Hollow nanosphere; Adsorption property
KeyWords Plus: SPHERES; OXIDES; NANOSTRUCTURES; FABRICATION; ROUTE
通讯作者地址: Guo, SW (通讯作者), Shanghai Jiao Tong Univ, Natl Key Lab Nano Micro
Fabricat Technol, Key Lab Thin Film & Microfabricat, Minist Educ,Res Inst Micro Nano Sci &
Technol, Shanghai 200240, Peoples R China
地址:
1. Shanghai Jiao Tong Univ, Natl Key Lab Nano Micro Fabricat Technol, Key Lab Thin Film &
Microfabricat, Minist Educ,Res Inst Micro Nano Sci & Technol, Shanghai 200240, Peoples R
China
2. E China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai 200237, Peoples R China
3. E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
电子邮件地址: jyzhang@ecust.edu.cn, swguo@sjtu.edu.cn
基金资助致谢:
基金资助机构 授权号
National Basic Research Program (973 program) of China 2007CB936000
National High Technology Research and Development Program (863 program) of China
2006AA04Z309
Shanghai Pujiang Scholarship Program 06PJ14025 ;06PJ14030
出版商: SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA
学 科 类 别 : Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics,
Applied
IDS 号: 495HH
ISSN: 1931-7573
DOI: 10.1007/s11671-009-9383-x
8、
标题：Metabonomic characterization of aging and investigation on the anti-aging effects of
total flavones of Epimedium
作者: Yan SK (Yan, Shikai)3, Wu B (Wu, Bin)1, Lin ZY (Lin, Zhongying)2, Jin HZ (Jin, Huizi)3,
Huang JH (Huang, Jianhua)1, Yang Y (Yang, Yun)3, Zhang XM (Zhang, Xinmin)1, Shen ZY
(Shen, Ziyin)1, Zhang WD (Zhang, Weidong)2,3
来源出版物: MOLECULAR BIOSYSTEMS
卷: 5
期: 10
页: 1204-1213
出版
年: 2009
被引频次: 0
参考文献: 63
摘要: A liquid chromatography coupled with mass spectrometry (LC/MS) based metabonomics
approach was applied to characterize the aging of rats, and the anti-aging effect of total flavones of
Epimedium (TFE), a traditional Chinese medicine, has also been investigated. Serum samples
collected from 4, 10, 18 and 24 month-old rats and TFE-administered rats have been pro. led by
LC/MS. Thirty age-related endogenous metabolites were discovered by partial least squares (PLS)
and Hotelling's T-2 control chart, among which 25 metabolites were structurally identified by MSn
analysis and ten of them were further confirmed via authentic chemicals. All important age-related
metabolites, such as unsaturated fatty acids, saturated fatty acids, nucleotides, carnosine,
ergothioneine and amino acids, displayed age-related changes, and most of them were reset to a
younger level after TFE administration. This study indicated that aging could be characterized by
changes of lipid metabolisms and accumulation of free radicals. The anti-aging effects of TFE
might due to the intervention on lipid metabolism and its property of anti-oxidation.
文献类型: Article
语言: English
KeyWords Plus: COMPONENT ANALYSIS; SERUM-CHOLESTEROL; IN-VITRO;
METABOLITES; LONGEVITY; PROTEIN; RAT; PERFORMANCE; SENESCENCE;
OXIDATION
通讯作者地址: Shen, ZY (通讯作者), Fudan Univ, Huashan Hosp, Inst Integrat Chinese &
Western Med, Shanghai 200424, Peoples R China
地址:
1. Fudan Univ, Huashan Hosp, Inst Integrat Chinese & Western Med, Shanghai 200424, Peoples R
China
2. Mil Med Coll 2, Sch Pharm, Shanghai 200433, Peoples R China
3. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
电子邮件地址: ziyinshen@126.com, wdzhangy@hotmail.com
基金资助致谢:
基金资助机构 授权号
Changjiang Scholars and Innovative Research Team in University (PCSIRT)
NCET Foundation
NSFC 30600794 ;30725045
973 Program 2007CB507400
National 863 Program 2006AA02Z338
Shanghai Leading Academic Discipline Project B906
Scientific Foundation of Shanghai China 07DZ19728 ;06DZ19717 ;06DZ19005
出 版 商 : ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK,
MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
学科类别: Biochemistry & Molecular Biology
IDS 号: 494SF
ISSN: 1742-206X
DOI: 10.1039/b816407j
9、
标题：Purification and Characterization of a Radical Scavenging Peptide from Rapeseed
Protein Hydrolysates
作者: Zhang SB (Zhang, Shao Bing)1,2, Wang Z (Wang, Zhang)1, Xu SY (Xu, Shi Ying)1, Gao
XF (Gao, Xian Fu)3
来源出版物: JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
卷: 86
期:
10
页: 959-966
出版年: OCT 2009
被引频次: 0
参考文献: 33
摘要: We previously reported that crude rapeseed peptides (CRPs) and peptide fractions (RP25
and RP55) prepared from aqueous enzymatic extraction of rapeseed exhibited marked antioxidant
activities, among which RP55 showed the most potent effects. In the present study, RP55 was
further purified using consecutive chromatographic methods for identification of antioxidant
peptides. The alpha,alpha-diphenyl-beta-picrylhydrazyl (DPPH) radical scavenging effects of
peptides were measured at each purification step to evaluate the antioxidant activities. RP55 was
first fractionated by anion-exchange chromatography, and three fractions (E1, E2, and E3) were
obtained. All of them showed significantly lower scavenging activities compared to RP55, which
was very probably due to the remarkable loss of tannin during the separation. Next, the active
fraction E2 with higher protein content was sequentially purified by gel filtration chromatography
(GFC) and reversed-phase high performance liquid chromatography (RP-HPLC). The purified
peptide, of which the median effective dose (ED50) value for DPPH radical scavenging was 0.063
mg/mL, was identified to be Pro-Ala-Gly-Pro-Phe (487 Da) using electrospray ionization (ESI)
mass spectrometry. The unique amino acid composition and sequence in the peptide might play an
important role in expression of its antioxidant activity.
文献类型: Article
语言: English
作者关键词: Rapeseed peptides; Radical scavenger; alpha,alpha-diphenyl-beta-picrylhydrazyl
(DPPH); Purification; Electrospray ionization mass spectrometry
KeyWords Plus: AQUEOUS ENZYMATIC EXTRACTION; ANTIOXIDATIVE PEPTIDES;
SOYBEAN PROTEIN; EGG-YOLK; IDENTIFICATION; SKIN; OIL; DIGESTS; SYSTEM
通讯作者地址: Wang, Z (通讯作者), Jiangnan Univ, State Key Lab Food Sci & Technol, Sch
Food Sci & Technol, Wuxi 214122, Jiangsu Peoples R China
地址:
1. Jiangnan Univ, State Key Lab Food Sci & Technol, Sch Food Sci & Technol, Wuxi 214122,
Jiangsu Peoples R China
2. Henan Univ Technol, Sch Food Sci & Technol, Zhengzhou 450052, Henan Peoples R China
3. Shanghai Jiao Tong Univ, Sch Pharm, Shanghai 200240, Peoples R China
电子邮件地址: shoabing99@hotmail.com, zw@sytu.edu.cn
出版商: SPRINGER, 233 SPRING ST, NEW YORK, NY 10013 USA
学科类别: Chemistry, Applied; Food Science & Technology
IDS 号: 495HD
ISSN: 0003-021X
DOI: 10.1007/s11746-009-1404-5